locus-tag	class	description
G6536_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G6536_00010	COG0592	DNA-directed DNA polymerase activity
G6536_00015	COG2501	S4 domain
G6536_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G6536_00030	COG0187	DNA topoisomerase II activity
G6536_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G6536_00070	COG0516	GMP reductase activity
G6536_00070	COG0517	IMP dehydrogenase activity
G6536_00075	COG1686	Belongs to the peptidase S11 family
G6536_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
G6536_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
G6536_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G6536_00100	COG1929	Belongs to the glycerate kinase type-1 family
G6536_00105	COG2610	gluconate transmembrane transporter activity
G6536_00110	COG3835	regulator
G6536_00125	COG1428	Deoxynucleoside kinase
G6536_00130	COG1428	Deoxynucleoside kinase
G6536_00135	COG1388	LysM domain
G6536_00135	COG3858	chitin binding
G6536_00140	COG1335	isochorismatase
G6536_00145	COG0590	tRNA wobble adenosine to inosine editing
G6536_00155	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G6536_00160	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
G6536_00165	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G6536_00210	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
G6536_00215	COG3853	Toxic anion resistance protein (TelA)
G6536_00220	COG1982	Orn Lys Arg decarboxylase major
G6536_00225	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
G6536_00230	COG3870	Protein conserved in bacteria
G6536_00235	COG1728	Protein conserved in bacteria
G6536_00240	COG0470	DNA polymerase III
G6536_00245	COG1774	PSP1 C-terminal conserved region
G6536_00250	COG4467	Involved in initiation control of chromosome replication
G6536_00255	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
G6536_00260	COG2827	Endonuclease containing a URI domain
G6536_00265	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
G6536_00270	COG2002	toxin-antitoxin pair type II binding
G6536_00275	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G6536_00275	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G6536_00280	COG0084	hydrolase, TatD family'
G6536_00285	COG3583	domain protein
G6536_00285	COG3584	3D domain protein
G6536_00290	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
G6536_00295	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G6536_00305	COG4466	Protein conserved in bacteria
G6536_00315	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
G6536_00320	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G6536_00325	COG0251	oxidation-reduction process
G6536_00330	COG2088	sporulation resulting in formation of a cellular spore
G6536_00335	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G6536_00340	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G6536_00345	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
G6536_00350	COG0193	aminoacyl-tRNA hydrolase activity
G6536_00360	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G6536_00365	COG2002	toxin-antitoxin pair type II binding
G6536_00370	COG2244	polysaccharide biosynthetic process
G6536_00375	COG3956	TIGRFAM MazG family protein
G6536_00380	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
G6536_00395	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
G6536_00400	COG1098	S1 RNA binding domain
G6536_00415	COG2208	phosphoserine phosphatase activity
G6536_00420	COG2304	oxidoreductase activity
G6536_00425	COG0515	serine threonine protein kinase
G6536_00430	COG0037	tRNA processing
G6536_00435	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
G6536_00440	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G6536_00445	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
G6536_00450	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
G6536_00455	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G6536_00460	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G6536_00470	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G6536_00475	COG0512	Glutamine amidotransferase of anthranilate synthase
G6536_00480	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G6536_00485	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G6536_00490	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G6536_00495	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G6536_00500	COG1396	sequence-specific DNA binding
G6536_00505	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G6536_00510	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G6536_00590	COG4463	regulation of RNA biosynthetic process
G6536_00595	COG3880	PFAM UvrB UvrC protein
G6536_00600	COG3869	Catalyzes the specific phosphorylation of arginine residues in
G6536_00605	COG0542	response to heat
G6536_00610	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
G6536_00615	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
G6536_00620	COG4956	integral membrane protein (PIN domain superfamily)
G6536_00625	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G6536_00630	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
G6536_00635	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G6536_00640	COG1045	serine acetyltransferase
G6536_00645	COG0215	cysteine-tRNA ligase activity
G6536_00650	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
G6536_00655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G6536_00660	COG3688	RNA-binding protein containing a PIN domain
G6536_00670	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G6536_00680	COG0250	Participates in transcription elongation, termination and antitermination
G6536_00685	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
G6536_00690	COG0081	regulation of translation
G6536_00695	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G6536_00700	COG0222	ribosome binding
G6536_00705	COG2813	Specifically methylates the guanine in position
G6536_00710	COG0085	RNA polymerase activity
G6536_00715	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G6536_00720	COG1358	cellular component organization or biogenesis
G6536_00725	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G6536_00730	COG0049	tRNA binding
G6536_00735	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G6536_00740	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G6536_00750	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G6536_00755	COG0088	Forms part of the polypeptide exit tunnel
G6536_00760	COG0089	rRNA binding
G6536_00765	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G6536_00770	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G6536_00775	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G6536_00780	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
G6536_00785	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
G6536_00790	COG0255	Belongs to the universal ribosomal protein uL29 family
G6536_00795	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G6536_00800	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G6536_00805	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
G6536_00810	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G6536_00815	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G6536_00820	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G6536_00825	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G6536_00830	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
G6536_00835	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G6536_00840	COG1841	ribosomal large subunit assembly
G6536_00845	COG0200	Binds to the 23S rRNA
G6536_00850	COG0201	protein transport
G6536_00855	COG0563	adenylate kinase activity
G6536_00860	COG0024	Methionine aminopeptidase
G6536_00865	COG2163	COG2163 Ribosomal protein L14E L6E L27E
G6536_00870	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G6536_00875	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G6536_00880	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G6536_00885	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
G6536_00890	COG0202	RNA polymerase activity
G6536_00895	COG0203	ribosomal protein L17
G6536_00900	COG1122	ATPase activity
G6536_00905	COG1122	ATPase activity
G6536_00910	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
G6536_00915	COG0101	tRNA pseudouridine synthase activity
G6536_00920	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G6536_00925	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G6536_00930	COG2318	DinB family
G6536_00940	COG0860	N-Acetylmuramoyl-L-alanine amidase
G6536_00945	COG0489	protein tyrosine kinase activity
G6536_00955	COG2194	sulfuric ester hydrolase activity
G6536_00960	COG0726	polysaccharide deacetylase
G6536_00995	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G6536_01005	COG0385	Bile acid
G6536_01020	COG3876	Protein conserved in bacteria
G6536_01025	COG1472	Belongs to the glycosyl hydrolase 3 family
G6536_01030	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G6536_01035	COG1263	PTS System
G6536_01035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G6536_01040	COG1737	Transcriptional regulator
G6536_01045	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
G6536_01050	COG1683	Conserved Protein
G6536_01085	COG1595	DNA-templated transcription, initiation
G6536_01090	COG5662	AntiSigma factor
G6536_01095	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
G6536_01100	COG4856	YbbR-like protein
G6536_01105	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G6536_01110	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G6536_01130	COG1725	Transcriptional regulator
G6536_01135	COG0640	Transcriptional regulator
G6536_01140	COG2814	Major facilitator Superfamily
G6536_01150	COG1132	(ABC) transporter
G6536_01155	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G6536_01180	COG1011	Hydrolase
G6536_01185	COG1113	amino acid transport
G6536_01190	COG2851	Citrate transporter
G6536_01195	COG3181	Tripartite tricarboxylate transporter family receptor
G6536_01200	COG4565	transcriptional regulatory protein
G6536_01205	COG3290	protein histidine kinase activity
G6536_01220	COG2211	Major facilitator Superfamily
G6536_01240	COG1331	Highly conserved protein containing a thioredoxin domain
G6536_01245	COG3677	Transposase
G6536_01280	COG1331	Highly conserved protein containing a thioredoxin domain
G6536_01290	COG0477	Major facilitator Superfamily
G6536_01310	COG1283	sodium-dependent phosphate transmembrane transporter activity
G6536_01315	COG4682	membrane
G6536_01340	COG0697	spore germination
G6536_01345	COG2207	Transcriptional regulator
G6536_01345	COG1917	Cupin 2, conserved barrel domain protein
G6536_01365	COG0371	Dehydrogenase
G6536_01370	COG0840	transmembrane signaling receptor activity
G6536_01375	COG4213	ABC transporter substrate-binding protein
G6536_01390	COG4257	antibiotic catabolic process
G6536_01400	COG0833	amino acid
G6536_01405	COG2040	homocysteine
G6536_01415	COG2190	(PTS) system
G6536_01415	COG1263	PTS System
G6536_01415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G6536_01420	COG0789	Transcriptional regulator
G6536_01425	COG2323	membrane
G6536_01430	COG4451	ribulose bisphosphate carboxylase, small
G6536_01430	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
G6536_01440	COG2205	protein histidine kinase activity
G6536_01445	COG1115	amino acid carrier protein
G6536_01450	COG2066	Belongs to the glutaminase family
G6536_01455	COG4191	Histidine kinase
G6536_01460	COG0784	Response regulator, receiver
G6536_01485	COG3540	Alkaline phosphatase
G6536_01490	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G6536_01495	COG0805	protein transport
G6536_01500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6536_01505	COG1012	belongs to the aldehyde dehydrogenase family
G6536_01510	COG2271	Major facilitator Superfamily
G6536_01515	COG4948	Mandelate Racemase Muconate Lactonizing
G6536_01520	COG2186	Transcriptional regulator
G6536_01525	COG2721	sulfolactate sulfo-lyase activity
G6536_01530	COG0745	RESPONSE REGULATOR receiver
G6536_01535	COG2205	protein histidine kinase activity
G6536_01540	COG1131	(ABC) transporter
G6536_01565	COG3173	Aminoglycoside phosphotransferase
G6536_01570	COG1846	Transcriptional regulator
G6536_01575	COG0318	PFAM AMP-dependent synthetase and ligase
G6536_01600	COG0789	Transcriptional regulator
G6536_01625	COG0697	spore germination
G6536_01630	COG1714	RDD family
G6536_01635	COG3012	SEC-C Motif Domain Protein
G6536_01635	COG1405	negative regulation of cell septum assembly
G6536_01640	COG1131	(ABC) transporter
G6536_01665	COG0583	DNA-binding transcription factor activity
G6536_01670	COG1942	4-Oxalocrotonate Tautomerase
G6536_01675	COG1028	Short-chain dehydrogenase reductase Sdr
G6536_01690	COG1288	antiporter activity
G6536_01700	COG0456	acetyltransferase
G6536_01710	COG1164	Oligoendopeptidase f
G6536_01715	COG2261	transglycosylase associated protein
G6536_01725	COG0247	lactate metabolic process
G6536_01730	COG0277	FAD linked oxidase domain protein
G6536_01735	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G6536_01740	COG1447	Phosphotransferase system cellobiose-specific component IIA
G6536_01745	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G6536_01750	COG1486	melibiose metabolic process
G6536_01755	COG2188	Transcriptional regulator
G6536_01760	COG3394	polysaccharide catabolic process
G6536_01775	COG3591	Belongs to the peptidase S1B family
G6536_01780	COG1028	Short-chain dehydrogenase reductase Sdr
G6536_01790	COG1595	DNA-templated transcription, initiation
G6536_01800	COG3773	Cell wall hydrolase
G6536_01805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6536_01810	COG0791	NLP P60 protein
G6536_01810	COG3883	PFAM NLP P60 protein
G6536_01820	COG1131	(ABC) transporter
G6536_01825	COG1309	transcriptional regulator
G6536_01845	COG2310	stress, protein
G6536_01850	COG2310	stress, protein
G6536_01855	COG2310	stress, protein
G6536_01860	COG0861	Integral membrane protein TerC family
G6536_01880	COG3853	Toxic anion resistance protein (TelA)
G6536_01885	COG0785	Cytochrome C biogenesis protein
G6536_01895	COG0789	Transcriptional regulator
G6536_01900	COG2223	nitrite transmembrane transporter activity
G6536_01905	COG0039	L-malate dehydrogenase activity
G6536_01910	COG1620	l-lactate permease
G6536_01915	COG1280	lysine exporter protein (LysE YggA)
G6536_01920	COG1113	amino acid transport
G6536_01925	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G6536_01930	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G6536_01935	COG3541	Predicted nucleotidyltransferase
G6536_01940	COG0506	proline dehydrogenase activity
G6536_01945	COG1012	belongs to the aldehyde dehydrogenase family
G6536_01950	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G6536_01955	COG2508	Transcriptional regulator
G6536_01960	COG3689	TIGRFAM TIGR03943 family protein
G6536_01965	COG0701	Predicted permease
G6536_01970	COG3458	cephalosporin-C deacetylase activity
G6536_01990	COG0765	amino acid transport
G6536_01995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G6536_02000	COG2249	NAD(P)H dehydrogenase (quinone) activity
G6536_02010	COG2723	6-phospho-beta-galactosidase activity
G6536_02020	COG3209	COG3209 Rhs family protein
G6536_02030	COG3266	domain, Protein
G6536_02030	COG0515	serine threonine protein kinase
G6536_02040	COG5444	nuclease activity
G6536_02065	COG1176	ABC-type spermidine putrescine transport system, permease component I
G6536_02070	COG1177	transmembrane transport
G6536_02075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6536_02080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6536_02085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6536_02090	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
G6536_02095	COG0697	spore germination
G6536_02100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G6536_02110	COG2819	hydrolase of the alpha beta superfamily
G6536_02120	COG2364	Membrane
G6536_02130	COG1131	(ABC) transporter
G6536_02160	COG1126	abc transporter atp-binding protein
G6536_02165	COG0765	amino acid transport
G6536_02170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G6536_02175	COG3829	transcription factor binding
G6536_02180	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G6536_02185	COG0833	amino acid
G6536_02190	COG0010	Belongs to the arginase family
G6536_02195	COG0583	DNA-binding transcription factor activity
G6536_02200	COG0163	prenyltransferase activity
G6536_02205	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
G6536_02255	COG5444	nuclease activity
G6536_02275	COG2972	Histidine kinase
G6536_02280	COG4753	response regulator
G6536_02280	COG2207	Transcriptional regulator
G6536_02285	COG4213	ABC transporter substrate-binding protein
G6536_02295	COG4214	carbohydrate transport
G6536_02300	COG2271	Major facilitator Superfamily
G6536_02305	COG0456	acetyltransferase
G6536_02305	COG1846	Transcriptional regulator
G6536_02310	COG1874	Beta-galactosidase
G6536_02315	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
G6536_02320	COG3104	oligopeptide transport
G6536_02325	COG5434	Belongs to the glycosyl hydrolase 28 family
G6536_02335	COG0697	spore germination
G6536_02345	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
G6536_02350	COG0789	Transcriptional regulator
G6536_02355	COG1136	(ABC) transporter
G6536_02360	COG0577	efflux transmembrane transporter activity
G6536_02365	COG0745	RESPONSE REGULATOR receiver
G6536_02370	COG3850	Histidine kinase
G6536_02370	COG5002	protein histidine kinase activity
G6536_02380	COG0527	aspartate kinase activity
G6536_02385	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G6536_02390	COG4605	iron ion homeostasis
G6536_02395	COG4604	ABC transporter, ATP-binding protein
G6536_02400	COG4607	ABC-type enterochelin transport system periplasmic component
G6536_02405	COG2814	Major facilitator Superfamily
G6536_02410	COG1309	transcriptional regulator
G6536_02420	COG0778	Nitroreductase
G6536_02425	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
G6536_02430	COG0640	Transcriptional regulator
G6536_02435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G6536_02440	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G6536_02445	COG0531	amino acid
G6536_02450	COG1012	belongs to the aldehyde dehydrogenase family
G6536_02465	COG4549	nuclear export factor GLE1
G6536_02470	COG1276	copper resistance
G6536_02470	COG2372	response to copper ion
G6536_02475	COG1349	DNA-binding transcription factor activity
G6536_02480	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G6536_02485	COG0243	molybdopterin cofactor binding
G6536_02490	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G6536_02495	COG2146	nitrite reductase [NAD(P)H] activity
G6536_02500	COG1587	Uroporphyrinogen-III synthase
G6536_02500	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G6536_02505	COG1802	Transcriptional regulator
G6536_02510	COG0471	metal ion transport
G6536_02515	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G6536_02530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G6536_02545	COG3959	Transketolase, thiamine diphosphate binding domain
G6536_02550	COG3958	Transketolase
G6536_02555	COG0561	phosphatase activity
G6536_02560	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
G6536_02565	COG1914	H( )-stimulated, divalent metal cation uptake system
G6536_02570	COG4336	lyase activity
G6536_02575	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
G6536_02580	COG1984	allophanate hydrolase subunit 2
G6536_02585	COG1414	Transcriptional regulator
G6536_02590	COG2755	lipolytic protein G-D-S-L family
G6536_02595	COG2213	PTS system mannitol-specific
G6536_02600	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
G6536_02605	COG0246	Mannitol dehydrogenase
G6536_02610	COG3711	transcriptional antiterminator
G6536_02615	COG1028	Short-chain dehydrogenase reductase Sdr
G6536_02620	COG1917	Cupin 2, conserved barrel domain protein
G6536_02630	COG3871	stress protein (general stress protein 26)
G6536_02645	COG2814	Major facilitator Superfamily
G6536_02655	COG1522	sequence-specific DNA binding
G6536_02660	COG0551	DNA topoisomerase type I activity
G6536_02660	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G6536_02665	COG0531	amino acid
G6536_02670	COG0028	Belongs to the TPP enzyme family
G6536_02675	COG3397	chitin binding
G6536_02685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G6536_02690	COG1914	H( )-stimulated, divalent metal cation uptake system
G6536_02695	COG2261	transglycosylase associated protein
G6536_02700	COG1027	Aspartate ammonia-lyase
G6536_02705	COG1819	glycosyl
G6536_02710	COG4876	unkown
G6536_02715	COG2217	Heavy metal translocating P-type atpase
G6536_02725	COG0662	Cupin 2, conserved barrel domain protein
G6536_02730	COG3729	General stress protein
G6536_02735	COG0628	permease
G6536_02740	COG1301	dicarboxylic acid transport
G6536_02745	COG1131	(ABC) transporter
G6536_02750	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
G6536_02760	COG1960	acyl-CoA dehydrogenase activity
G6536_02775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G6536_02780	COG1181	Belongs to the D-alanine--D-alanine ligase family
G6536_02785	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G6536_02795	COG0513	Belongs to the DEAD box helicase family
G6536_02800	COG3402	PFAM membrane-flanked domain
G6536_02805	COG3428	Bacterial PH domain
G6536_02810	COG0705	Rhomboid family
G6536_02815	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
G6536_02820	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G6536_02825	COG0864	Transcriptional regulator
G6536_02830	COG2337	Toxic component of a toxin-antitoxin (TA) module
G6536_02835	COG1366	Belongs to the anti-sigma-factor antagonist family
G6536_02840	COG1366	Belongs to the anti-sigma-factor antagonist family
G6536_02845	COG2172	sigma factor antagonist activity
G6536_02850	COG2208	phosphoserine phosphatase activity
G6536_02860	COG2172	sigma factor antagonist activity
G6536_02865	COG1191	sigma factor activity
G6536_02870	COG2208	phosphoserine phosphatase activity
G6536_02875	COG2183	response to ionizing radiation
G6536_02880	COG1309	transcriptional regulator
G6536_02885	COG2409	Drug exporters of the RND superfamily
G6536_02885	COG1033	growth of symbiont in host cell
G6536_02895	COG3091	SprT-like family
G6536_02940	COG1476	TRANSCRIPTIONal
G6536_02945	COG3239	Fatty acid desaturase
G6536_02950	COG1278	Cold shock
G6536_02965	COG2364	Membrane
G6536_02970	COG1846	Transcriptional regulator
G6536_02975	COG0456	acetyltransferase
G6536_02980	COG2808	Putative FMN-binding domain
G6536_02990	COG1733	regulation of RNA biosynthetic process
G6536_02995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G6536_03005	COG0583	DNA-binding transcription factor activity
G6536_03025	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
G6536_03030	COG1113	amino acid transport
G6536_03045	COG1595	DNA-templated transcription, initiation
G6536_03055	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G6536_03055	COG2755	lipolytic protein G-D-S-L family
G6536_03060	COG2814	Major facilitator Superfamily
G6536_03070	COG3279	Response regulator of the LytR AlgR family
G6536_03080	COG3764	Sortase (surface protein transpeptidase)
G6536_03085	COG2814	Major facilitator Superfamily
G6536_03125	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
G6536_03130	COG0802	atpase or kinase
G6536_03135	COG1214	PFAM Peptidase M22, glycoprotease
G6536_03140	COG0456	acetyltransferase
G6536_03145	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G6536_03150	COG0488	(ABC) transporter
G6536_03155	COG0315	cyclic pyranopterin monophosphate synthase activity
G6536_03160	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
G6536_03165	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G6536_03170	COG0805	protein transport
G6536_03180	COG1266	CAAX protease self-immunity
G6536_03185	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
G6536_03190	COG0459	protein refolding
G6536_03220	COG2720	vancomycin resistance protein
G6536_03235	COG2135	peptidase activity
G6536_03245	COG1309	transcriptional regulator
G6536_03250	COG3848	Pyruvate phosphate dikinase
G6536_03250	COG0574	Belongs to the PEP-utilizing enzyme family
G6536_03260	COG3189	MarR family transcriptional regulator
G6536_03265	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
G6536_03270	COG2272	Belongs to the type-B carboxylesterase lipase family
G6536_03275	COG2814	Major facilitator Superfamily
G6536_03280	COG1842	Phage shock protein A
G6536_03285	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G6536_03290	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
G6536_03295	COG4260	virion core protein, lumpy skin disease virus
G6536_03305	COG1378	Sugar-specific transcriptional regulator TrmB
G6536_03310	COG1280	lysine exporter protein (LysE YggA)
G6536_03315	COG3339	Conserved Protein
G6536_03320	COG0772	Belongs to the SEDS family
G6536_03325	COG0772	Belongs to the SEDS family
G6536_03350	COG0726	polysaccharide deacetylase
G6536_03360	COG1609	Transcriptional regulator
G6536_03365	COG0366	Alpha amylase catalytic
G6536_03370	COG2182	Extracellular solute-binding protein
G6536_03375	COG1175	transmembrane transport
G6536_03380	COG3833	ABC-type maltose transport systems, permease component
G6536_03385	COG5521	maltodextrose utilization protein MalA
G6536_03390	COG1554	hydrolase, family 65, central catalytic
G6536_03395	COG0366	Alpha amylase catalytic
G6536_03400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G6536_03405	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G6536_03410	COG1846	Transcriptional regulator
G6536_03425	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G6536_03430	COG0823	Involved in the tonB-independent uptake of proteins
G6536_03465	COG0702	epimerase
G6536_03475	COG2132	Multicopper oxidase
G6536_03490	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
G6536_03495	COG0714	Associated with various cellular activities
G6536_03500	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
G6536_03505	COG1305	Transglutaminase-like
G6536_03510	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G6536_03510	COG0519	Catalyzes the synthesis of GMP from XMP
G6536_03520	COG2252	PERMEase
G6536_03535	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
G6536_03545	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
G6536_03550	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G6536_03555	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G6536_03560	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G6536_03565	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G6536_03570	COG0047	phosphoribosylformylglycinamidine synthase activity
G6536_03575	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G6536_03580	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
G6536_03585	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G6536_03590	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G6536_03595	COG0138	bifunctional purine biosynthesis protein purh
G6536_03600	COG0151	Belongs to the GarS family
G6536_03610	COG2124	cytochrome p450
G6536_03630	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
G6536_03635	COG1470	cell adhesion involved in biofilm formation
G6536_03640	COG4496	protein, YerC YecD
G6536_03645	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
G6536_03650	COG0210	DNA helicase
G6536_03655	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G6536_03660	COG4851	CamS sex pheromone cAM373 precursor
G6536_03665	COG2188	Transcriptional regulator
G6536_03685	COG1735	metal-dependent hydrolase with the TIM-barrel fold
G6536_03690	COG0626	cystathionine gamma-synthase activity
G6536_03695	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
G6536_03700	COG3457	Alanine racemase
G6536_03705	COG0363	glucosamine-6-phosphate deaminase activity
G6536_03710	COG1285	pathogenesis
G6536_03715	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G6536_03725	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G6536_03730	COG0154	amidase activity
G6536_03735	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G6536_03750	COG4124	Belongs to the glycosyl hydrolase 26 family
G6536_03755	COG1309	transcriptional regulator
G6536_03760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G6536_03770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G6536_03775	COG1957	nucleoside hydrolase
G6536_03780	COG1597	lipid kinase activity
G6536_03785	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G6536_03795	COG1263	PTS System
G6536_03795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G6536_03795	COG2190	(PTS) system
G6536_03800	COG2723	6-phospho-beta-galactosidase activity
G6536_03805	COG3711	transcriptional antiterminator
G6536_03810	COG0457	Tetratricopeptide repeat
G6536_03825	COG0217	transcriptional regulatory protein
G6536_03840	COG1012	belongs to the aldehyde dehydrogenase family
G6536_03845	COG0840	transmembrane signaling receptor activity
G6536_03850	COG0471	metal ion transport
G6536_03855	COG0488	(ABC) transporter
G6536_03865	COG1469	GTP cyclohydrolase I activity
G6536_03880	COG0523	cobalamin synthesis protein
G6536_03885	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
G6536_03890	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G6536_03895	COG0156	8-amino-7-oxononanoate synthase activity
G6536_03900	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
G6536_03905	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
G6536_03910	COG2124	cytochrome p450
G6536_03920	COG0789	Transcriptional regulator
G6536_03925	COG2814	Major facilitator Superfamily
G6536_03930	COG0488	(ABC) transporter
G6536_03935	COG0513	Belongs to the DEAD box helicase family
G6536_03940	COG2130	NADP-dependent
G6536_03955	COG0471	metal ion transport
G6536_03970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6536_03980	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
G6536_03985	COG5658	integral membrane protein
G6536_03990	COG0640	Transcriptional regulator
G6536_03995	COG1254	Belongs to the acylphosphatase family
G6536_04000	COG2258	MOSC domain
G6536_04015	COG0024	Methionine aminopeptidase
G6536_04020	COG1368	sulfuric ester hydrolase activity
G6536_04035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G6536_04035	COG1263	PTS System
G6536_04040	COG0366	Alpha amylase catalytic
G6536_04045	COG2188	Transcriptional regulator
G6536_04070	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G6536_04075	COG1045	serine acetyltransferase
G6536_04080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G6536_04090	COG1215	transferase activity, transferring glycosyl groups
G6536_04095	COG0463	Glycosyl transferase, family 2
G6536_04095	COG0457	Tetratricopeptide repeat
G6536_04105	COG0673	inositol 2-dehydrogenase activity
G6536_04115	COG0657	acetylesterase activity
G6536_04120	COG1733	regulation of RNA biosynthetic process
G6536_04125	COG0778	Nitroreductase
G6536_04130	COG0737	Belongs to the 5'-nucleotidase family
G6536_04135	COG0693	protein deglycase activity
G6536_04140	COG4840	Belongs to the UPF0435 family
G6536_04145	COG1115	amino acid carrier protein
G6536_04150	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G6536_04155	COG4980	gas vesicle protein
G6536_04160	COG1295	ribonuclease BN
G6536_04165	COG0477	Major facilitator Superfamily
G6536_04175	COG0387	Pfam Sodium calcium exchanger
G6536_04185	COG0535	radical SAM domain protein
G6536_04195	COG0726	polysaccharide deacetylase
G6536_04200	COG0371	Dehydrogenase
G6536_04210	COG0598	Magnesium transport protein CorA
G6536_04215	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
G6536_04220	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G6536_04225	COG4637	Psort location Cytoplasmic, score
G6536_04250	COG1819	glycosyl
G6536_04260	COG0477	Major facilitator Superfamily
G6536_04265	COG1263	PTS System
G6536_04265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G6536_04270	COG3711	transcriptional antiterminator
G6536_04275	COG0288	reversible hydration of carbon dioxide
G6536_04280	COG3002	Belongs to the UPF0753 family
G6536_04285	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G6536_04290	COG5609	conserved protein (DUF2294)
G6536_04300	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G6536_04305	COG0022	dehydrogenase e1 component
G6536_04310	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6536_04315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G6536_04325	COG1742	UPF0060 membrane protein
G6536_04330	COG1486	melibiose metabolic process
G6536_04335	COG1737	Transcriptional regulator
G6536_04340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G6536_04340	COG1263	PTS System
G6536_04355	COG1733	regulation of RNA biosynthetic process
G6536_04360	COG2259	Doxx family
G6536_04365	COG2514	catechol 2,3-dioxygenase activity
G6536_04375	COG3507	Belongs to the glycosyl hydrolase 43 family
G6536_04380	COG1917	Cupin 2, conserved barrel domain protein
G6536_04380	COG2207	Transcriptional regulator
G6536_04385	COG1653	transport
G6536_04390	COG2249	NAD(P)H dehydrogenase (quinone) activity
G6536_04395	COG1051	belongs to the nudix hydrolase family
G6536_04405	COG0392	lysyltransferase activity
G6536_04405	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
G6536_04410	COG0384	phenazine biosynthesis protein PhzF
G6536_04415	COG0778	Nitroreductase
G6536_04435	COG1090	epimerase
G6536_04440	COG2137	regulation of response to DNA damage stimulus
G6536_04470	COG0463	Glycosyl transferase, family 2
G6536_04480	COG4485	Bacterial membrane protein, YfhO
G6536_04485	COG1988	membrane-bound metal-dependent
G6536_04490	COG1194	a g-specific adenine glycosylase
G6536_04500	COG1028	Short-chain dehydrogenase reductase Sdr
G6536_04515	COG3557	Belongs to the UPF0374 family
G6536_04520	COG1132	(ABC) transporter
G6536_04525	COG0444	Belongs to the ABC transporter superfamily
G6536_04530	COG4608	Belongs to the ABC transporter superfamily
G6536_04535	COG0747	negative chemotaxis
G6536_04540	COG0601	transmembrane transport
G6536_04545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6536_04550	COG4129	membrane
G6536_04555	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G6536_04560	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G6536_04565	COG0735	belongs to the Fur family
G6536_04790	COG0582	viral genome integration into host DNA
G6536_04825	COG1802	Transcriptional regulator
G6536_04825	COG4626	Terminase
G6536_04885	COG5280	Phage tail tape measure protein TP901
G6536_04885	COG3953	SLT domain
G6536_04895	COG1705	Flagellar rod assembly protein muramidase FlgJ
G6536_04900	COG5434	Belongs to the glycosyl hydrolase 28 family
G6536_04940	COG5444	nuclease activity
G6536_04945	COG0457	Tetratricopeptide repeat
G6536_04960	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G6536_04970	COG0457	Tetratricopeptide repeat
G6536_05010	COG5444	nuclease activity
G6536_05015	COG0457	Tetratricopeptide repeat
G6536_05030	COG0710	3-dehydroquinate dehydratase activity
G6536_05035	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
G6536_05040	COG1116	anion transmembrane transporter activity
G6536_05045	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G6536_05050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6536_05055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6536_05065	COG1476	TRANSCRIPTIONal
G6536_05075	COG1131	(ABC) transporter
G6536_05095	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G6536_05105	COG3382	B3 4 domain protein
G6536_05110	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
G6536_05120	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G6536_05125	COG0789	Transcriptional regulator
G6536_05130	COG1664	Polymer-forming cytoskeletal
G6536_05140	COG2766	serine protein kinase
G6536_05145	COG2718	Belongs to the UPF0229 family
G6536_05150	COG1566	PFAM secretion protein HlyD family protein
G6536_05155	COG2814	Major facilitator Superfamily
G6536_05160	COG0655	NAD(P)H dehydrogenase (quinone) activity
G6536_05180	COG1131	(ABC) transporter
G6536_05185	COG1131	(ABC) transporter
G6536_05190	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
G6536_05195	COG1278	Cold shock
G6536_05200	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G6536_05205	COG2011	ABC-type metal ion transport system permease component
G6536_05210	COG1464	Belongs to the NlpA lipoprotein family
G6536_05215	COG1823	symporter activity
G6536_05240	COG5577	PFAM Coat F domain
G6536_05245	COG5002	protein histidine kinase activity
G6536_05250	COG0737	Belongs to the 5'-nucleotidase family
G6536_05250	COG1525	nuclease
G6536_05250	COG4085	toxin activity
G6536_05255	COG3764	Sortase (surface protein transpeptidase)
G6536_05260	COG0564	pseudouridine synthase activity
G6536_05270	COG0517	IMP dehydrogenase activity
G6536_05275	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G6536_05280	COG3153	acetyltransferase
G6536_05280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G6536_05290	COG0488	(ABC) transporter
G6536_05295	COG2116	formate transmembrane transporter activity
G6536_05300	COG0679	Auxin Efflux Carrier
G6536_05305	COG0604	alcohol dehydrogenase
G6536_05310	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
G6536_05315	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G6536_05320	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G6536_05325	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G6536_05330	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G6536_05345	COG2203	Gaf domain
G6536_05345	COG4585	Histidine kinase
G6536_05350	COG2197	response regulator
G6536_05355	COG0431	NADPH-dependent FMN reductase
G6536_05370	COG1959	2 iron, 2 sulfur cluster binding
G6536_05375	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G6536_05375	COG1017	nitric oxide dioxygenase activity
G6536_05380	COG2719	SpoVR family
G6536_05385	COG1388	LysM domain
G6536_05385	COG0791	NLP P60 protein
G6536_05390	COG0583	DNA-binding transcription factor activity
G6536_05395	COG0372	Belongs to the citrate synthase family
G6536_05400	COG2133	pyrroloquinoline quinone binding
G6536_05405	COG1028	Short-chain dehydrogenase reductase Sdr
G6536_05410	COG0733	neurotransmitter:sodium symporter activity
G6536_05420	COG2207	Transcriptional regulator
G6536_05420	COG3708	Transcriptional regulator
G6536_05445	COG1595	DNA-templated transcription, initiation
G6536_05450	COG0662	Cupin 2, conserved barrel domain protein
G6536_05460	COG0204	Acyl-transferase
G6536_05465	COG3152	Membrane
G6536_05475	COG1309	transcriptional regulator
G6536_05480	COG1253	flavin adenine dinucleotide binding
G6536_05485	COG0789	Transcriptional regulator
G6536_05490	COG1253	flavin adenine dinucleotide binding
G6536_05510	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G6536_05515	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G6536_05520	COG0584	glycerophosphoryl diester phosphodiesterase
G6536_05530	COG0668	transmembrane transport
G6536_05535	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G6536_05545	COG0726	polysaccharide deacetylase
G6536_05555	COG1757	Na H antiporter
G6536_05560	COG2017	converts alpha-aldose to the beta-anomer
G6536_05585	COG0589	response to stress
G6536_05590	COG1132	(ABC) transporter
G6536_05595	COG1132	(ABC) transporter
G6536_05600	COG0702	epimerase
G6536_05620	COG3842	ATPase activity
G6536_05625	COG2508	Transcriptional regulator
G6536_05635	COG0189	ligase activity
G6536_05640	COG0189	ligase activity
G6536_05645	COG4399	Belongs to the UPF0754 family
G6536_05650	COG3679	Belongs to the UPF0342 family
G6536_05660	COG0561	phosphatase activity
G6536_05665	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G6536_05670	COG0475	glutathione-regulated potassium exporter activity
G6536_05675	COG0490	domain, Protein
G6536_05685	COG1024	Enoyl-CoA hydratase
G6536_05690	COG0457	Tetratricopeptide repeat
G6536_05710	COG4152	abc transporter atp-binding protein
G6536_05715	COG1668	transmembrane transport
G6536_05720	COG0420	3'-5' exonuclease activity
G6536_05725	COG4717	serine-type aminopeptidase activity
G6536_05730	COG3481	metal-dependent phosphohydrolase, HD sub domain
G6536_05740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G6536_05770	COG1846	Transcriptional regulator
G6536_05775	COG4980	gas vesicle protein
G6536_05790	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
G6536_05795	COG0537	adenosine 5'-monophosphoramidase activity
G6536_05800	COG1131	(ABC) transporter
G6536_05805	COG4473	ABC transporter
G6536_05815	COG1473	amidohydrolase
G6536_05825	COG2329	Antibiotic biosynthesis monooxygenase
G6536_05830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G6536_05835	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G6536_05840	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
G6536_05845	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
G6536_05850	COG1309	transcriptional regulator
G6536_05855	COG1511	domain protein
G6536_05860	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G6536_05865	COG1363	Peptidase, m42
G6536_05875	COG1301	dicarboxylic acid transport
G6536_05885	COG1234	tRNA 3'-trailer cleavage
G6536_05890	COG0095	Lipoate-protein ligase
G6536_05895	COG0318	PFAM AMP-dependent synthetase and ligase
G6536_05905	COG1396	sequence-specific DNA binding
G6536_05920	COG0501	Belongs to the peptidase M48B family
G6536_05930	COG0697	spore germination
G6536_05935	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
G6536_05940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G6536_05945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G6536_05950	COG0406	alpha-ribazole phosphatase activity
G6536_05955	COG0840	transmembrane signaling receptor activity
G6536_05960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6536_05960	COG0723	plastoquinol--plastocyanin reductase activity
G6536_05965	COG1028	Short-chain dehydrogenase reductase Sdr
G6536_05975	COG4903	ComK protein
G6536_05985	COG0398	Pfam SNARE associated Golgi protein
G6536_05990	COG0681	Belongs to the peptidase S26 family
G6536_05995	COG1404	Belongs to the peptidase S8 family
G6536_06000	COG2003	Belongs to the UPF0758 family
G6536_06005	COG2189	Belongs to the N(4) N(6)-methyltransferase family
G6536_06010	COG3421	Type III restriction
G6536_06025	COG2508	Transcriptional regulator
G6536_06035	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G6536_06045	COG3257	ureidoglycine aminohydrolase activity
G6536_06050	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
G6536_06055	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
G6536_06060	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
G6536_06065	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
G6536_06075	COG0549	Belongs to the carbamate kinase family
G6536_06080	COG2814	Major facilitator Superfamily
G6536_06090	COG0457	Tetratricopeptide repeat
G6536_06100	COG1609	Transcriptional regulator
G6536_06105	COG1653	transport
G6536_06110	COG1175	transmembrane transport
G6536_06115	COG0395	ABC-type sugar transport system, permease component
G6536_06120	COG1486	melibiose metabolic process
G6536_06125	COG3180	Ammonia monooxygenase
G6536_06140	COG3546	catalase activity
G6536_06145	COG0318	PFAM AMP-dependent synthetase and ligase
G6536_06150	COG0477	Major facilitator Superfamily
G6536_06150	COG2814	Major facilitator Superfamily
G6536_06155	COG4533	DNA binding
G6536_06165	COG5002	protein histidine kinase activity
G6536_06170	COG0745	RESPONSE REGULATOR receiver
G6536_06175	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
G6536_06180	COG0725	ABC transporter, periplasmic molybdate-binding protein
G6536_06185	COG4149	molybdate abc transporter
G6536_06190	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
G6536_06195	COG1074	ATP-dependent DNA helicase activity
G6536_06200	COG0420	3'-5' exonuclease activity
G6536_06205	COG0419	ATPase involved in DNA repair
G6536_06250	COG5337	Spore coat protein CotH
G6536_06260	COG0179	Fumarylacetoacetate (FAA) hydrolase
G6536_06280	COG0367	asparagine synthase
G6536_06285	COG0004	ammonium transporteR
G6536_06295	COG0534	Mate efflux family protein
G6536_06300	COG2207	Transcriptional regulator
G6536_06300	COG1917	Cupin 2, conserved barrel domain protein
G6536_06310	COG1609	Transcriptional regulator
G6536_06315	COG0673	inositol 2-dehydrogenase activity
G6536_06320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G6536_06330	COG0076	glutamate decarboxylase activity
G6536_06355	COG2153	protein acetylation
G6536_06360	COG1028	Short-chain dehydrogenase reductase Sdr
G6536_06365	COG2378	regulation of single-species biofilm formation
G6536_06370	COG0646	methionine synthase
G6536_06370	COG1410	methionine synthase
G6536_06375	COG0646	methionine synthase
G6536_06375	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
G6536_06380	COG1666	GTP binding
G6536_06385	COG2996	Protein conserved in bacteria
G6536_06400	COG1307	EDD domain protein, DegV family
G6536_06405	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G6536_06415	COG0516	GMP reductase activity
G6536_06430	COG0561	phosphatase activity
G6536_06435	COG1073	alpha beta
G6536_06440	COG2151	metal-sulfur cluster biosynthetic enzyme
G6536_06455	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G6536_06460	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
G6536_06465	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G6536_06470	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G6536_06475	COG0505	Belongs to the CarA family
G6536_06480	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G6536_06485	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G6536_06490	COG1968	undecaprenyl-diphosphatase activity
G6536_06505	COG2267	carboxylic ester hydrolase activity
G6536_06515	COG1744	ABC transporter substrate-binding protein PnrA-like
G6536_06530	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G6536_06535	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G6536_06540	COG5504	Zn-dependent protease
G6536_06545	COG0444	Belongs to the ABC transporter superfamily
G6536_06550	COG4608	Belongs to the ABC transporter superfamily
G6536_06560	COG0601	transmembrane transport
G6536_06565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6536_06580	COG0180	Tryptophanyl-tRNA synthetase
G6536_06585	COG4166	transmembrane transport
G6536_06590	COG0601	transmembrane transport
G6536_06595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6536_06600	COG0444	Belongs to the ABC transporter superfamily
G6536_06605	COG4608	Belongs to the ABC transporter superfamily
G6536_06610	COG0456	acetyltransferase
G6536_06615	COG1393	Belongs to the ArsC family
G6536_06620	COG0861	Integral membrane protein TerC family
G6536_06630	COG4862	establishment of competence for transformation
G6536_06650	COG4565	transcriptional regulatory protein
G6536_06655	COG3290	protein histidine kinase activity
G6536_06660	COG4469	Competence protein
G6536_06665	COG1164	Oligoendopeptidase f
G6536_06670	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G6536_06675	COG2346	COG2346, Truncated hemoglobins
G6536_06685	COG4116	CYTH
G6536_06695	COG2357	RelA SpoT domain protein
G6536_06700	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G6536_06705	COG0564	pseudouridine synthase activity
G6536_06710	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G6536_06720	COG0475	glutathione-regulated potassium exporter activity
G6536_06720	COG0569	domain protein
G6536_06725	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
G6536_06730	COG0352	thiamine-phosphate diphosphorylase activity
G6536_06740	COG2104	thiamine diphosphate biosynthetic process
G6536_06745	COG2022	thiamine diphosphate biosynthetic process
G6536_06750	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G6536_06755	COG0351	phosphomethylpyrimidine kinase
G6536_06760	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G6536_06815	COG0210	DNA helicase
G6536_06825	COG0586	Pfam SNARE associated Golgi protein
G6536_06830	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G6536_06835	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G6536_06840	COG2246	polysaccharide biosynthetic process
G6536_06845	COG2153	protein acetylation
G6536_06850	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
G6536_06855	COG2382	esterase
G6536_06875	COG0626	cystathionine gamma-synthase activity
G6536_06880	COG0626	cystathionine gamma-synthase activity
G6536_06885	COG5505	Protein of unknown function (DUF819)
G6536_06905	COG3507	Belongs to the glycosyl hydrolase 43 family
G6536_06925	COG0110	maltose O-acetyltransferase activity
G6536_06935	COG0583	DNA-binding transcription factor activity
G6536_06940	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G6536_06945	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G6536_06950	COG0583	DNA-binding transcription factor activity
G6536_06955	COG0697	spore germination
G6536_06960	COG0346	lactoylglutathione lyase activity
G6536_06970	COG3584	3D domain protein
G6536_06970	COG1388	LysM domain
G6536_06975	COG2814	Major facilitator Superfamily
G6536_06980	COG1309	transcriptional regulator
G6536_07000	COG5444	nuclease activity
G6536_07005	COG4195	phage-related replication protein
G6536_07010	COG2856	Zn peptidase
G6536_07015	COG1396	sequence-specific DNA binding
G6536_07030	COG1522	sequence-specific DNA binding
G6536_07035	COG1484	DNA-dependent DNA replication
G6536_07055	COG1595	DNA-templated transcription, initiation
G6536_07060	COG5484	DNA packaging
G6536_07060	COG3728	DNA packaging
G6536_07065	COG1783	phage Terminase large subunit
G6536_07070	COG5518	Phage portal protein
G6536_07075	COG0338	D12 class N6 adenine-specific DNA methyltransferase
G6536_07080	COG4653	Phage capsid family
G6536_07130	COG5412	phage tail tape measure protein
G6536_07130	COG3953	SLT domain
G6536_07135	COG1652	LysM domain
G6536_07140	COG4193	domain, Protein
G6536_07150	COG3628	GPW Gp25 family protein
G6536_07155	COG3299	homolog of phage Mu protein gp47
G6536_07160	COG3778	Protein conserved in bacteria
G6536_07200	COG1802	Transcriptional regulator
G6536_07205	COG1063	alcohol dehydrogenase
G6536_07210	COG1312	Catalyzes the dehydration of D-mannonate
G6536_07215	COG1028	Short-chain dehydrogenase reductase Sdr
G6536_07220	COG1063	alcohol dehydrogenase
G6536_07225	COG2271	Major facilitator Superfamily
G6536_07240	COG0306	phosphate transporter
G6536_07245	COG1392	Phosphate transport regulator
G6536_07250	COG0405	Gamma-glutamyltransferase
G6536_07255	COG5578	integral membrane protein
G6536_07260	COG2972	Histidine kinase
G6536_07265	COG4753	response regulator
G6536_07265	COG2207	Transcriptional regulator
G6536_07270	COG1653	transport
G6536_07275	COG1175	transmembrane transport
G6536_07280	COG0395	ABC-type sugar transport system, permease component
G6536_07285	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
G6536_07290	COG2207	Transcriptional regulator
G6536_07295	COG2755	lipolytic protein G-D-S-L family
G6536_07305	COG5578	integral membrane protein
G6536_07310	COG3401	FG-GAP repeat protein
G6536_07320	COG2755	lipolytic protein G-D-S-L family
G6536_07325	COG3401	FG-GAP repeat protein
G6536_07330	COG0667	Aldo Keto reductase
G6536_07335	COG2755	lipolytic protein G-D-S-L family
G6536_07340	COG1874	Beta-galactosidase
G6536_07350	COG1653	transport
G6536_07355	COG4209	transmembrane transport
G6536_07360	COG0395	ABC-type sugar transport system, permease component
G6536_07365	COG0531	amino acid
G6536_07370	COG0346	lactoylglutathione lyase activity
G6536_07380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6536_07385	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G6536_07390	COG2362	D-Aminopeptidase
G6536_07395	COG0601	transmembrane transport
G6536_07400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6536_07405	COG0444	Belongs to the ABC transporter superfamily
G6536_07410	COG4166	transmembrane transport
G6536_07415	COG1619	proteins homologs of microcin C7 resistance protein MccF
G6536_07420	COG4948	Mandelate Racemase Muconate Lactonizing
G6536_07425	COG0791	NLP P60 protein
G6536_07430	COG4608	Belongs to the ABC transporter superfamily
G6536_07435	COG1834	amidinotransferase
G6536_07440	COG1607	acyl-coa hydrolase
G6536_07450	COG2323	membrane
G6536_07475	COG2318	DinB family
G6536_07480	COG2076	Multidrug Resistance protein
G6536_07485	COG2076	Multidrug Resistance protein
G6536_07490	COG0788	formyltetrahydrofolate deformylase activity
G6536_07495	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G6536_07500	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G6536_07505	COG1764	response to oxidative stress
G6536_07510	COG1846	Transcriptional regulator
G6536_07515	COG1764	response to oxidative stress
G6536_07525	COG0590	tRNA wobble adenosine to inosine editing
G6536_07530	COG0406	alpha-ribazole phosphatase activity
G6536_07545	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G6536_07550	COG1404	Belongs to the peptidase S8 family
G6536_07560	COG2239	Acts as a magnesium transporter
G6536_07570	COG0789	Transcriptional regulator
G6536_07585	COG1846	Transcriptional regulator
G6536_07590	COG3285	dna ligase
G6536_07590	COG1793	dna ligase
G6536_07595	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
G6536_07600	COG5001	Diguanylate cyclase
G6536_07600	COG3300	MHYT domain
G6536_07605	COG0586	Pfam SNARE associated Golgi protein
G6536_07610	COG0861	Integral membrane protein TerC family
G6536_07615	COG1191	sigma factor activity
G6536_07635	COG0501	Belongs to the peptidase M48B family
G6536_07640	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G6536_07645	COG0768	penicillin binding
G6536_07660	COG3594	Acyltransferase
G6536_07665	COG5002	protein histidine kinase activity
G6536_07670	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G6536_07675	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
G6536_07680	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
G6536_07685	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G6536_07690	COG0436	Aminotransferase
G6536_07695	COG1850	ribulose-bisphosphate carboxylase activity
G6536_07700	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
G6536_07700	COG0235	Class ii aldolase
G6536_07705	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
G6536_07710	COG0346	lactoylglutathione lyase activity
G6536_07715	COG3339	Conserved Protein
G6536_07725	COG3852	Histidine kinase
G6536_07730	COG1846	Transcriptional regulator
G6536_07735	COG1360	Flagellar Motor Protein
G6536_07740	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G6536_07745	COG0542	response to heat
G6536_07750	COG3949	Membrane
G6536_07755	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
G6536_07760	COG0720	synthase
G6536_07765	COG0602	queuosine metabolic process
G6536_07770	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G6536_07775	COG4974	Belongs to the 'phage' integrase family
G6536_07780	COG4974	Belongs to the 'phage' integrase family
G6536_07810	COG1793	dna ligase
G6536_07845	COG5444	nuclease activity
G6536_07930	COG0582	viral genome integration into host DNA
G6536_08055	COG5632	N-Acetylmuramoyl-L-alanine amidase
G6536_08055	COG3409	Peptidoglycan-binding domain 1 protein
G6536_08055	COG1388	LysM domain
G6536_08080	COG0582	viral genome integration into host DNA
G6536_08095	COG3739	integral membrane protein
G6536_08100	COG3655	Transcriptional regulator
G6536_08140	COG4873	Protein conserved in bacteria
G6536_08150	COG3773	Cell wall hydrolase
G6536_08155	COG2244	polysaccharide biosynthetic process
G6536_08160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G6536_08165	COG2217	Heavy metal translocating P-type atpase
G6536_08170	COG0006	proline dipeptidase activity
G6536_08180	COG1609	Transcriptional regulator
G6536_08185	COG3711	transcriptional antiterminator
G6536_08190	COG1263	PTS System
G6536_08190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G6536_08190	COG2190	(PTS) system
G6536_08195	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G6536_08200	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G6536_08210	COG1533	DNA photolyase activity
G6536_08215	COG0456	acetyltransferase
G6536_08220	COG0840	transmembrane signaling receptor activity
G6536_08225	COG1028	Short-chain dehydrogenase reductase Sdr
G6536_08230	COG2084	Dehydrogenase
G6536_08235	COG2340	Cysteine-rich secretory protein family
G6536_08240	COG0768	penicillin binding
G6536_08245	COG4191	Histidine kinase
G6536_08250	COG0436	Aminotransferase
G6536_08260	COG1714	RDD family
G6536_08270	COG0784	Response regulator, receiver
G6536_08270	COG0835	chemotaxis
G6536_08280	COG2814	Major facilitator Superfamily
G6536_08285	COG1376	ErfK ybiS ycfS ynhG family protein
G6536_08290	COG1408	metallophosphoesterase
G6536_08295	COG1028	Short-chain dehydrogenase reductase Sdr
G6536_08300	COG2200	EAL domain
G6536_08310	COG4703	Protein of unknown function (DUF1797)
G6536_08320	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
G6536_08330	COG0517	IMP dehydrogenase activity
G6536_08335	COG0583	DNA-binding transcription factor activity
G6536_08340	COG0716	FMN binding
G6536_08350	COG0716	FMN binding
G6536_08355	COG2171	N-acyltransferase activity
G6536_08360	COG1473	amidohydrolase
G6536_08370	COG0450	alkyl hydroperoxide reductase
G6536_08375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G6536_08390	COG0746	molybdenum cofactor guanylyltransferase activity
G6536_08395	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G6536_08400	COG0303	'Molybdopterin
G6536_08405	COG1763	Mo-molybdopterin cofactor biosynthetic process
G6536_08410	COG0314	molybdopterin synthase activity
G6536_08415	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
G6536_08425	COG1132	(ABC) transporter
G6536_08430	COG1132	(ABC) transporter
G6536_08440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G6536_08445	COG1136	(ABC) transporter
G6536_08450	COG0577	efflux transmembrane transporter activity
G6536_08455	COG1349	DNA-binding transcription factor activity
G6536_08460	COG1105	Belongs to the carbohydrate kinase PfkB family
G6536_08465	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G6536_08465	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G6536_08465	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G6536_08485	COG0488	(ABC) transporter
G6536_08495	COG2309	aminopeptidase activity
G6536_08505	COG1077	Cell shape determining protein MreB Mrl
G6536_08510	COG2002	toxin-antitoxin pair type II binding
G6536_08515	COG3852	Histidine kinase
G6536_08520	COG0569	domain protein
G6536_08525	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
G6536_08530	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
G6536_08535	COG5503	Protein of unknown function (DUF1447)
G6536_08540	COG0561	phosphatase activity
G6536_08545	COG0242	peptide deformylase activity
G6536_08555	COG0497	DNA recombination
G6536_08560	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G6536_08565	COG0022	dehydrogenase e1 component
G6536_08570	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6536_08575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G6536_08580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G6536_08590	COG1982	Orn Lys Arg decarboxylase major
G6536_08595	COG4476	Belongs to the UPF0223 family
G6536_08600	COG4493	Belongs to the UPF0637 family
G6536_08610	COG0483	inositol monophosphate 1-phosphatase activity
G6536_08630	COG1595	DNA-templated transcription, initiation
G6536_08645	COG1217	gtp-binding protein TYPA
G6536_08655	COG1846	Transcriptional regulator
G6536_08660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6536_08665	COG4896	Protein conserved in bacteria
G6536_08675	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G6536_08680	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G6536_08685	COG2066	Belongs to the glutaminase family
G6536_08690	COG4838	Belongs to the UPF0358 family
G6536_08695	COG0772	Belongs to the SEDS family
G6536_08700	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
G6536_08705	COG1612	heme a metabolic process
G6536_08710	COG0109	protoheme IX farnesyltransferase activity
G6536_08715	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G6536_08715	COG2010	Cytochrome c
G6536_08720	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G6536_08725	COG1845	cytochrome c oxidase, subunit III
G6536_08730	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
G6536_08735	COG3336	cytochrome c oxidase
G6536_08745	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
G6536_08750	COG2340	Cysteine-rich secretory protein family
G6536_08765	COG3679	Belongs to the UPF0342 family
G6536_08770	COG4471	UPF0298 protein
G6536_08775	COG0742	ribosomal rna small subunit methyltransferase
G6536_08780	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G6536_08785	COG3314	Sporulation integral membrane protein YlbJ
G6536_08790	COG3480	Lon protease (S16) C-terminal proteolytic domain
G6536_08795	COG1323	Belongs to the UPF0348 family
G6536_08800	COG1399	metal-binding, possibly nucleic acid-binding protein
G6536_08805	COG0333	Belongs to the bacterial ribosomal protein bL32 family
G6536_08815	COG0454	-acetyltransferase
G6536_08820	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G6536_08825	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
G6536_08830	COG2001	Belongs to the MraZ family
G6536_08835	COG0275	rRNA processing
G6536_08840	COG4839	cell division protein FtsL
G6536_08845	COG0768	penicillin binding
G6536_08850	COG0768	penicillin binding
G6536_08855	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G6536_08860	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G6536_08865	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G6536_08870	COG0772	Belongs to the SEDS family
G6536_08875	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G6536_08880	COG0812	UDP-N-acetylmuramate dehydrogenase activity
G6536_08885	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G6536_08890	COG3879	Bacterial protein of unknown function (DUF881)
G6536_08895	COG3879	Bacterial protein of unknown function (DUF881)
G6536_08900	COG3856	small basic protein
G6536_08905	COG0849	cell division
G6536_08910	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G6536_08915	COG1404	Belongs to the peptidase S8 family
G6536_08915	COG4412	M6 family metalloprotease domain protein
G6536_08920	COG1404	Belongs to the peptidase S8 family
G6536_08920	COG4412	M6 family metalloprotease domain protein
G6536_08930	COG1191	sigma factor activity
G6536_08935	COG1191	sigma factor activity
G6536_08940	COG1119	ATPase activity
G6536_08945	COG0500	methyltransferase
G6536_08950	COG1873	PFAM PRC-barrel domain
G6536_08955	COG1496	oxidoreductase activity
G6536_08960	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
G6536_08965	COG1799	cell septum assembly
G6536_08970	COG0762	integral membrane protein
G6536_08975	COG2302	S4 RNA-binding domain
G6536_08980	COG3599	regulation of cell shape
G6536_08985	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G6536_08990	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G6536_08995	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
G6536_09000	COG0564	pseudouridine synthase activity
G6536_09005	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
G6536_09010	COG2233	PERMEase
G6536_09015	COG0540	Belongs to the ATCase OTCase family
G6536_09020	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G6536_09025	COG0505	Belongs to the CarA family
G6536_09030	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G6536_09035	COG0543	2 iron, 2 sulfur cluster binding
G6536_09040	COG0167	dihydroorotate dehydrogenase activity
G6536_09045	COG0284	orotidine-5'-phosphate decarboxylase activity
G6536_09050	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G6536_09060	COG0175	sulfate reduction
G6536_09065	COG0306	phosphate transporter
G6536_09070	COG2046	Belongs to the sulfate adenylyltransferase family
G6536_09075	COG0529	Catalyzes the synthesis of activated sulfate
G6536_09080	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G6536_09085	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
G6536_09090	COG1648	precorrin-2 dehydrogenase activity
G6536_09100	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
G6536_09105	COG1561	YicC-like family, N-terminal region
G6536_09110	COG2052	Domain of unknown function (DUF370)
G6536_09115	COG0194	GDP metabolic process
G6536_09120	COG1758	RNA polymerase activity
G6536_09125	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G6536_09130	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G6536_09135	COG0242	peptide deformylase activity
G6536_09140	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G6536_09145	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G6536_09145	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G6536_09150	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G6536_09155	COG0631	protein serine/threonine phosphatase activity
G6536_09160	COG2815	serine threonine protein kinase
G6536_09160	COG0515	serine threonine protein kinase
G6536_09165	COG1162	GTPase activity
G6536_09170	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G6536_09175	COG1564	THIamine pyrophosphokinase
G6536_09185	COG0227	Belongs to the bacterial ribosomal protein bL28 family
G6536_09190	COG1302	Protein conserved in bacteria
G6536_09195	COG1461	Dihydroxyacetone kinase
G6536_09200	COG1760	l-serine dehydratase
G6536_09205	COG1760	l-serine dehydratase
G6536_09210	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G6536_09215	COG1349	DNA-binding transcription factor activity
G6536_09220	COG0416	fatty acid biosynthetic process
G6536_09225	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
G6536_09230	COG1028	Short-chain dehydrogenase reductase Sdr
G6536_09235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G6536_09240	COG0571	ribonuclease III activity
G6536_09245	COG1196	nuclear chromosome segregation
G6536_09250	COG0552	protein localization to endoplasmic reticulum
G6536_09255	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
G6536_09260	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G6536_09265	COG0228	four-way junction DNA binding
G6536_09270	COG1837	Belongs to the UPF0109 family
G6536_09280	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G6536_09285	COG0336	Belongs to the RNA methyltransferase TrmD family
G6536_09290	COG0335	large ribosomal subunit rRNA binding
G6536_09295	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
G6536_09300	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G6536_09310	COG2257	FlhB HrpN YscU SpaS Family
G6536_09315	COG0045	succinate-CoA ligase (ADP-forming) activity
G6536_09320	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
G6536_09325	COG0758	DNA mediated transformation
G6536_09330	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G6536_09335	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
G6536_09340	COG4974	Belongs to the 'phage' integrase family
G6536_09345	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
G6536_09350	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
G6536_09355	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
G6536_09360	COG1815	bacterial-type flagellum-dependent cell motility
G6536_09365	COG1558	bacterial-type flagellum-dependent cell motility
G6536_09370	COG1677	Flagellar hook-basal body complex protein FliE
G6536_09375	COG1766	The M ring may be actively involved in energy transduction
G6536_09380	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G6536_09385	COG1317	bacterial-type flagellum organization
G6536_09390	COG1157	protein secretion by the type III secretion system
G6536_09395	COG2882	bacterial-type flagellum organization
G6536_09405	COG3144	bacterial-type flagellum assembly
G6536_09410	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
G6536_09415	COG4786	Flagellar basal body rod
G6536_09420	COG1582	Flagellar protein (FlbD)
G6536_09425	COG1580	Controls the rotational direction of flagella during chemotaxis
G6536_09430	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G6536_09435	COG1776	CheC inhibitor of MCP methylation
G6536_09435	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G6536_09440	COG2201	protein-glutamate methylesterase activity
G6536_09445	COG3190	flagellar
G6536_09450	COG1338	Plays a role in the flagellum-specific transport system
G6536_09455	COG1987	bacterial-type flagellum assembly
G6536_09460	COG1684	flagellar biosynthetic protein fliR
G6536_09465	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G6536_09470	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G6536_09475	COG1419	protein localization to endoplasmic reticulum
G6536_09480	COG0455	bacterial-type flagellum organization
G6536_09490	COG0643	Histidine kinase
G6536_09490	COG2198	Histidine kinase
G6536_09495	COG0835	chemotaxis
G6536_09500	COG1776	CheC inhibitor of MCP methylation
G6536_09505	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
G6536_09510	COG1191	sigma factor activity
G6536_09520	COG0052	Belongs to the universal ribosomal protein uS2 family
G6536_09525	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G6536_09530	COG0528	UMP kinase activity
G6536_09535	COG0233	cytoplasmic translational termination
G6536_09540	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G6536_09545	COG4589	Belongs to the CDS family
G6536_09550	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
G6536_09555	COG0750	zinc metalloprotease
G6536_09560	COG0442	prolyl-tRNA aminoacylation
G6536_09565	COG2176	DNA-directed DNA polymerase activity
G6536_09595	COG0779	Required for maturation of 30S ribosomal subunits
G6536_09600	COG0195	Participates in both transcription termination and antitermination
G6536_09605	COG2740	Nucleic-acid-binding protein implicated in transcription termination
G6536_09610	COG1358	cellular component organization or biogenesis
G6536_09615	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
G6536_09620	COG1550	Protein conserved in bacteria
G6536_09625	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G6536_09630	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G6536_09635	COG0196	riboflavin kinase activity
G6536_09640	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G6536_09645	COG1185	polyribonucleotide nucleotidyltransferase activity
G6536_09650	COG0726	polysaccharide deacetylase
G6536_09655	COG0612	Peptidase, M16
G6536_09660	COG1873	PFAM PRC-barrel domain
G6536_09665	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G6536_09670	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G6536_09675	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G6536_09680	COG0527	aspartate kinase activity
G6536_09690	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
G6536_09695	COG0740	serine-type endopeptidase activity
G6536_09705	COG1674	ftsk spoiiie
G6536_09705	COG4980	gas vesicle protein
G6536_09710	COG2188	Transcriptional regulator
G6536_09715	COG2814	Major facilitator Superfamily
G6536_09720	COG0612	Peptidase, M16
G6536_09725	COG0612	Peptidase, M16
G6536_09730	COG0300	oxidoreductase activity
G6536_09745	COG1426	Protein conserved in bacteria
G6536_09750	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G6536_09755	COG1058	Belongs to the CinA family
G6536_09755	COG1546	Belongs to the CinA family
G6536_09765	COG1418	mRNA catabolic process
G6536_09770	COG1692	metallophosphoesterase
G6536_09775	COG2359	stage V sporulation protein S
G6536_09785	COG1063	alcohol dehydrogenase
G6536_09790	COG0156	8-amino-7-oxononanoate synthase activity
G6536_09795	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G6536_09800	COG4550	Control of competence regulator ComK, YlbF/YmcA
G6536_09810	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
G6536_09815	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G6536_09820	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
G6536_09825	COG5444	nuclease activity
G6536_09840	COG0523	cobalamin synthesis protein
G6536_09850	COG1247	-acetyltransferase
G6536_09870	COG3619	membrane
G6536_09875	COG3263	regulation of cellular component size
G6536_09895	COG0393	Putative heavy-metal-binding
G6536_09900	COG0398	Pfam SNARE associated Golgi protein
G6536_09905	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G6536_09910	COG1819	glycosyl
G6536_09915	COG0531	amino acid
G6536_09920	COG5577	PFAM Coat F domain
G6536_09930	COG1388	LysM domain
G6536_09930	COG3858	chitin binding
G6536_09935	COG1309	transcriptional regulator
G6536_09940	COG3631	Ketosteroid isomerase-related protein
G6536_09945	COG0702	epimerase
G6536_09955	COG1764	response to oxidative stress
G6536_09960	COG2076	Multidrug Resistance protein
G6536_09965	COG2076	Multidrug Resistance protein
G6536_09980	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G6536_09985	COG1923	regulation of RNA biosynthetic process
G6536_10000	COG1780	Probably involved in ribonucleotide reductase function
G6536_10005	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G6536_10010	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G6536_10015	COG4112	unkown
G6536_10030	COG0735	belongs to the Fur family
G6536_10035	COG1802	Transcriptional regulator
G6536_10040	COG0697	spore germination
G6536_10080	COG1309	transcriptional regulator
G6536_10130	COG0464	growth
G6536_10135	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G6536_10140	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
G6536_10145	COG0789	Transcriptional regulator
G6536_10150	COG0174	glutamine synthetase
G6536_10190	COG1073	alpha beta
G6536_10235	COG1309	transcriptional regulator
G6536_10240	COG2076	Multidrug Resistance protein
G6536_10245	COG2076	Multidrug Resistance protein
G6536_10250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G6536_10270	COG3546	catalase activity
G6536_10295	COG1846	Transcriptional regulator
G6536_10300	COG0778	Nitroreductase
G6536_10310	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G6536_10315	COG0655	NAD(P)H dehydrogenase (quinone) activity
G6536_10340	COG3209	COG3209 Rhs family protein
G6536_10345	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G6536_10350	COG1388	LysM domain
G6536_10355	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G6536_10360	COG4224	UPF0291 protein
G6536_10365	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G6536_10375	COG3763	UPF0154 protein
G6536_10385	COG0785	Cytochrome C biogenesis protein
G6536_10390	COG2201	protein-glutamate methylesterase activity
G6536_10395	COG4846	Membrane protein involved in cytochrome C biogenesis
G6536_10405	COG0071	Belongs to the small heat shock protein (HSP20) family
G6536_10420	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
G6536_10425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G6536_10445	COG0824	Thioesterase
G6536_10470	COG4841	protein insertion into membrane
G6536_10475	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
G6536_10480	COG1832	CoA-binding protein
G6536_10485	COG0187	DNA topoisomerase II activity
G6536_10490	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G6536_10495	COG1609	Transcriptional regulator
G6536_10510	COG2160	L-arabinose isomerase activity
G6536_10530	COG1115	amino acid carrier protein
G6536_10540	COG2181	nitrate reductase activity
G6536_10545	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
G6536_10550	COG1140	nitrate reductase beta subunit
G6536_10555	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
G6536_10570	COG0535	radical SAM domain protein
G6536_10575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G6536_10585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G6536_10590	COG2223	nitrite transmembrane transporter activity
G6536_10610	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
G6536_10620	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
G6536_10630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G6536_10640	COG0492	ferredoxin-NADP+ reductase activity
G6536_10655	COG3420	alginic acid biosynthetic process
G6536_10660	COG1114	Component of the transport system for branched-chain amino acids
G6536_10665	COG1064	alcohol dehydrogenase
G6536_10670	COG0789	Transcriptional regulator
G6536_10695	COG1024	Enoyl-CoA hydratase
G6536_10700	COG1012	belongs to the aldehyde dehydrogenase family
G6536_10705	COG2084	Dehydrogenase
G6536_10710	COG1960	acyl-CoA dehydrogenase activity
G6536_10715	COG1482	cell wall glycoprotein biosynthetic process
G6536_10720	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G6536_10720	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G6536_10720	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G6536_10740	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G6536_10740	COG3711	transcriptional antiterminator
G6536_10755	COG1725	Transcriptional regulator
G6536_10760	COG1028	Short-chain dehydrogenase reductase Sdr
G6536_10765	COG1312	Catalyzes the dehydration of D-mannonate
G6536_10780	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
G6536_10790	COG1609	Transcriptional regulator
G6536_10795	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G6536_10800	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
G6536_10805	COG0640	Transcriptional regulator
G6536_10810	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
G6536_10825	COG1649	PFAM Uncharacterised BCR, COG1649
G6536_10830	COG2404	hydrolase activity, acting on ester bonds
G6536_10835	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
G6536_10845	COG2027	D-alanyl-D-alanine carboxypeptidase
G6536_10850	COG1252	NADH dehydrogenase
G6536_10865	COG0166	Belongs to the GPI family
G6536_10875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G6536_10880	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6536_10885	COG1024	Enoyl-CoA hydratase
G6536_10890	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G6536_10895	COG0511	ligase activity, forming carbon-carbon bonds
G6536_10900	COG0439	Biotin carboxylase
G6536_10905	COG0318	PFAM AMP-dependent synthetase and ligase
G6536_10910	COG1960	acyl-CoA dehydrogenase activity
G6536_10915	COG2249	NAD(P)H dehydrogenase (quinone) activity
G6536_10920	COG1733	regulation of RNA biosynthetic process
G6536_10925	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G6536_10930	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G6536_10940	COG2323	membrane
G6536_10950	COG0306	phosphate transporter
G6536_10955	COG0175	sulfate reduction
G6536_10960	COG1809	phosphosulfolactate synthase activity
G6536_10965	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G6536_10970	COG4948	Mandelate Racemase Muconate Lactonizing
G6536_10975	COG2814	Major facilitator Superfamily
G6536_10980	COG0463	Glycosyl transferase, family 2
G6536_10995	COG0493	'glutamate synthase
G6536_11000	COG0067	glutamate synthase
G6536_11000	COG0070	glutamate synthase
G6536_11000	COG0069	glutamate synthase activity
G6536_11005	COG0583	DNA-binding transcription factor activity
G6536_11025	COG1846	Transcriptional regulator
G6536_11035	COG1132	(ABC) transporter
G6536_11045	COG0300	oxidoreductase activity
G6536_11050	COG0574	Belongs to the PEP-utilizing enzyme family
G6536_11050	COG3848	Pyruvate phosphate dikinase
G6536_11055	COG0477	Major facilitator Superfamily
G6536_11060	COG0243	molybdopterin cofactor binding
G6536_11065	COG1846	Transcriptional regulator
G6536_11075	COG0531	amino acid
G6536_11085	COG0531	amino acid
G6536_11090	COG0531	amino acid
G6536_11095	COG0697	spore germination
G6536_11100	COG0488	(ABC) transporter
G6536_11105	COG0840	transmembrane signaling receptor activity
G6536_11110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G6536_11115	COG1404	Belongs to the peptidase S8 family
G6536_11125	COG1309	transcriptional regulator
G6536_11130	COG1846	Transcriptional regulator
G6536_11160	COG1309	transcriptional regulator
G6536_11165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6536_11170	COG3708	Transcriptional regulator
G6536_11180	COG2378	regulation of single-species biofilm formation
G6536_11190	COG0640	Transcriptional regulator
G6536_11195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6536_11205	COG0531	amino acid
G6536_11210	COG0741	lytic transglycosylase activity
G6536_11215	COG1086	Polysaccharide biosynthesis protein
G6536_11235	COG2322	membrane
G6536_11250	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G6536_11255	COG3584	3D domain protein
G6536_11255	COG1388	LysM domain
G6536_11260	COG0514	ATP-dependent DNA helicase (RecQ)
G6536_11280	COG2315	Protein conserved in bacteria
G6536_11300	COG2427	Protein of unknown function (DUF1641)
G6536_11325	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
G6536_11375	COG0402	S-adenosylhomocysteine deaminase activity
G6536_11390	COG2267	carboxylic ester hydrolase activity
G6536_11405	COG1280	lysine exporter protein (LysE YggA)
G6536_11410	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G6536_11420	COG0574	Belongs to the PEP-utilizing enzyme family
G6536_11420	COG3848	Pyruvate phosphate dikinase
G6536_11425	COG1309	transcriptional regulator
G6536_11440	COG2318	DinB family
G6536_11445	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G6536_11450	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G6536_11465	COG1012	belongs to the aldehyde dehydrogenase family
G6536_11470	COG2814	Major facilitator Superfamily
G6536_11485	COG1657	PFAM Prenyltransferase squalene oxidase
G6536_11490	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G6536_11500	COG0733	neurotransmitter:sodium symporter activity
G6536_11510	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6536_11515	COG0567	Dehydrogenase, E1 component
G6536_11520	COG4548	von Willebrand factor, type A
G6536_11525	COG0714	Associated with various cellular activities
G6536_11530	COG2032	superoxide dismutase activity
G6536_11535	COG0791	NLP P60 protein
G6536_11535	COG1388	LysM domain
G6536_11545	COG0534	Mate efflux family protein
G6536_11550	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G6536_11555	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G6536_11565	COG2962	Rard protein
G6536_11575	COG4305	rare lipoprotein A
G6536_11585	COG1028	Short-chain dehydrogenase reductase Sdr
G6536_11590	COG1733	regulation of RNA biosynthetic process
G6536_11595	COG0778	Nitroreductase
G6536_11600	COG0400	carboxylic ester hydrolase activity
G6536_11610	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G6536_11615	COG3409	Peptidoglycan-binding domain 1 protein
G6536_11615	COG0793	Belongs to the peptidase S41A family
G6536_11620	COG2226	methyltransferase
G6536_11630	COG1876	peptidase activity
G6536_11635	COG0813	purine-nucleoside phosphorylase activity
G6536_11640	COG0701	Predicted permease
G6536_11660	COG0671	phosphoesterase, PA-phosphatase related
G6536_11675	COG4479	Belongs to the UPF0346 family
G6536_11685	COG1509	lysine 2,3-aminomutase activity
G6536_11690	COG0456	acetyltransferase
G6536_11695	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G6536_11700	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G6536_11705	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G6536_11710	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G6536_11730	COG0456	acetyltransferase
G6536_11735	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G6536_11740	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G6536_11745	COG1846	Transcriptional regulator
G6536_11755	COG3706	GGDEF domain
G6536_11760	COG0534	Mate efflux family protein
G6536_11775	COG4698	Protein conserved in bacteria
G6536_11780	COG2755	lipolytic protein G-D-S-L family
G6536_11785	COG1999	signal sequence binding
G6536_11800	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G6536_11805	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
G6536_11810	COG1272	protein, Hemolysin III
G6536_11815	COG0204	Acyl-transferase
G6536_11820	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
G6536_11830	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
G6536_11840	COG2136	Putative SAM-dependent methyltransferase
G6536_11840	COG2521	methyltransferase
G6536_11850	COG0129	dihydroxy-acid dehydratase activity
G6536_11855	COG1413	lyase activity
G6536_11860	COG1418	mRNA catabolic process
G6536_11865	COG0386	Belongs to the glutathione peroxidase family
G6536_11870	COG2759	Belongs to the formate--tetrahydrofolate ligase family
G6536_11875	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
G6536_11880	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G6536_11890	COG1278	Cold shock
G6536_11910	COG0328	RNA-DNA hybrid ribonuclease activity
G6536_11915	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
G6536_11920	COG0328	RNA-DNA hybrid ribonuclease activity
G6536_11930	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G6536_11945	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
G6536_11955	COG1755	Isoprenylcysteine carboxyl methyltransferase
G6536_11960	COG3424	synthase
G6536_11965	COG0456	acetyltransferase
G6536_11970	COG2233	PERMEase
G6536_11975	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G6536_11980	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
G6536_11985	COG1199	ATP-dependent helicase activity
G6536_12000	COG0116	Belongs to the methyltransferase superfamily
G6536_12010	COG3599	regulation of cell shape
G6536_12015	COG4474	Belongs to the UPF0398 family
G6536_12025	COG3359	exonuclease
G6536_12030	COG1111	helicase
G6536_12030	COG1205	dead DEAH box helicase
G6536_12035	COG2190	(PTS) system
G6536_12040	COG0071	Belongs to the small heat shock protein (HSP20) family
G6536_12075	COG3331	DNA recombination
G6536_12080	COG4499	WXG100 protein secretion system (Wss), protein YukC
G6536_12080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G6536_12090	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G6536_12095	COG3935	DnaD domain protein
G6536_12100	COG0017	Asparaginyl-tRNA synthetase
G6536_12105	COG0436	Aminotransferase
G6536_12110	COG5353	protein conserved in bacteria
G6536_12120	COG1199	ATP-dependent helicase activity
G6536_12120	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G6536_12125	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
G6536_12130	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G6536_12135	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
G6536_12150	COG0617	tRNA 3'-terminal CCA addition
G6536_12155	COG0438	transferase activity, transferring glycosyl groups
G6536_12160	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G6536_12165	COG1803	Methylglyoxal synthase
G6536_12170	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G6536_12175	COG1694	Mazg nucleotide pyrophosphohydrolase
G6536_12180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G6536_12190	COG4347	Protein of unknown function (DUF1405)
G6536_12200	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G6536_12200	COG2010	Cytochrome c
G6536_12205	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G6536_12210	COG0723	plastoquinol--plastocyanin reductase activity
G6536_12220	COG5582	Belongs to the UPF0302 family
G6536_12225	COG0457	Tetratricopeptide repeat
G6536_12230	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G6536_12235	COG0287	Prephenate dehydrogenase
G6536_12240	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G6536_12245	COG0159	tryptophan synthase activity
G6536_12250	COG0133	tryptophan synthase activity
G6536_12255	COG0135	phosphoribosylanthranilate isomerase activity
G6536_12260	COG0134	indole-3-glycerol-phosphate synthase activity
G6536_12265	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G6536_12270	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G6536_12275	COG4401	Chorismate mutase type I
G6536_12280	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
G6536_12285	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
G6536_12290	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
G6536_12295	COG0105	UTP biosynthetic process
G6536_12300	COG0142	geranyltranstransferase activity
G6536_12305	COG2226	methyltransferase
G6536_12310	COG0142	geranyltranstransferase activity
G6536_12325	COG0776	regulation of translation
G6536_12330	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
G6536_12350	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
G6536_12355	COG1160	GTP binding
G6536_12380	COG1304	FMN binding
G6536_12385	COG0539	negative regulation of cytoplasmic translation
G6536_12390	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
G6536_12400	COG2959	enzyme of heme biosynthesis
G6536_12405	COG3409	Peptidoglycan-binding domain 1 protein
G6536_12405	COG3773	Cell wall hydrolase
G6536_12410	COG2339	peptidase activity
G6536_12420	COG0492	ferredoxin-NADP+ reductase activity
G6536_12425	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G6536_12430	COG4862	establishment of competence for transformation
G6536_12435	COG1408	metallophosphoesterase
G6536_12445	COG1388	LysM domain
G6536_12450	COG1266	CAAX protease self-immunity
G6536_12455	COG0514	ATP-dependent DNA helicase (RecQ)
G6536_12460	COG4955	Helix-turn-helix domain
G6536_12465	COG1141	Ferredoxin
G6536_12470	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
G6536_12475	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G6536_12480	COG0739	heme binding
G6536_12490	COG1595	DNA-templated transcription, initiation
G6536_12495	COG1316	TRANSCRIPTIONal
G6536_12510	COG5002	protein histidine kinase activity
G6536_12515	COG0745	RESPONSE REGULATOR receiver
G6536_12520	COG5002	protein histidine kinase activity
G6536_12525	COG0745	RESPONSE REGULATOR receiver
G6536_12530	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G6536_12535	COG1333	cytochrome c biogenesis protein
G6536_12540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G6536_12545	COG1187	pseudouridine synthase activity
G6536_12550	COG0700	Nucleoside recognition
G6536_12555	COG2715	membrane protein required for spore maturation
G6536_12560	COG1686	Belongs to the peptidase S11 family
G6536_12570	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G6536_12575	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
G6536_12585	COG1547	Domain of unknown function (DUF309)
G6536_12590	COG0456	acetyltransferase
G6536_12595	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G6536_12600	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G6536_12600	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G6536_12605	COG0307	riboflavin synthase, alpha
G6536_12610	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G6536_12610	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G6536_12635	COG0457	Tetratricopeptide repeat
G6536_12640	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G6536_12645	COG4086	secreted protein
G6536_12650	COG4195	phage-related replication protein
G6536_12655	COG0019	diaminopimelate decarboxylase activity
G6536_12665	COG0697	spore germination
G6536_12680	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G6536_12715	COG1686	Belongs to the peptidase S11 family
G6536_12720	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
G6536_12725	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
G6536_12730	COG4974	Belongs to the 'phage' integrase family
G6536_12740	COG0735	belongs to the Fur family
G6536_12745	COG1300	Membrane
G6536_12750	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G6536_12770	COG2153	protein acetylation
G6536_12775	COG1379	DNA repair
G6536_12780	COG0494	nUDIX hydrolase
G6536_12790	COG1309	transcriptional regulator
G6536_12800	COG0667	Aldo Keto reductase
G6536_12810	COG1073	alpha beta
G6536_12820	COG4918	Iron-sulphur cluster biosynthesis
G6536_12830	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
G6536_12830	COG0456	acetyltransferase
G6536_12835	COG2329	Antibiotic biosynthesis monooxygenase
G6536_12840	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
G6536_12850	COG0747	negative chemotaxis
G6536_12855	COG0601	transmembrane transport
G6536_12860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6536_12865	COG0444	Belongs to the ABC transporter superfamily
G6536_12875	COG0534	Mate efflux family protein
G6536_12890	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G6536_12900	COG2211	Major facilitator Superfamily
G6536_12905	COG0346	lactoylglutathione lyase activity
G6536_12910	COG1072	(Pantothenic acid kinase))
G6536_12925	COG1131	(ABC) transporter
G6536_12945	COG4195	phage-related replication protein
G6536_12955	COG0300	oxidoreductase activity
G6536_12960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6536_12965	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G6536_12970	COG4187	Peptidase family M20/M25/M40
G6536_12975	COG1902	pentaerythritol trinitrate reductase activity
G6536_12985	COG0596	Alpha beta hydrolase
G6536_12990	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G6536_12995	COG1234	tRNA 3'-trailer cleavage
G6536_13000	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
G6536_13015	COG2358	TRAP transporter, solute receptor (TAXI family
G6536_13020	COG2188	Transcriptional regulator
G6536_13025	COG2723	6-phospho-beta-galactosidase activity
G6536_13030	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G6536_13035	COG1447	Phosphotransferase system cellobiose-specific component IIA
G6536_13040	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G6536_13045	COG1785	Belongs to the alkaline phosphatase family
G6536_13050	COG1028	Short-chain dehydrogenase reductase Sdr
G6536_13055	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
G6536_13060	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G6536_13070	COG0706	membrane insertase activity
G6536_13075	COG2195	Cleaves the N-terminal amino acid of tripeptides
G6536_13080	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6536_13090	COG4129	membrane
G6536_13095	COG1126	abc transporter atp-binding protein
G6536_13100	COG0765	amino acid transport
G6536_13105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G6536_13120	COG1597	lipid kinase activity
G6536_13125	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6536_13130	COG0022	dehydrogenase e1 component
G6536_13135	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G6536_13140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G6536_13145	COG3426	butyrate kinase activity
G6536_13155	COG0280	phosphate acetyltransferase
G6536_13160	COG3829	transcription factor binding
G6536_13160	COG3290	protein histidine kinase activity
G6536_13170	COG0584	glycerophosphoryl diester phosphodiesterase
G6536_13175	COG0860	N-Acetylmuramoyl-L-alanine amidase
G6536_13190	COG1045	serine acetyltransferase
G6536_13200	COG0745	RESPONSE REGULATOR receiver
G6536_13205	COG0750	zinc metalloprotease
G6536_13210	COG0497	DNA recombination
G6536_13215	COG1438	arginine binding
G6536_13220	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
G6536_13225	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
G6536_13230	COG0142	geranyltranstransferase activity
G6536_13235	COG1722	exodeoxyribonuclease VII activity
G6536_13240	COG1570	exodeoxyribonuclease VII activity
G6536_13245	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G6536_13250	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G6536_13255	COG1302	Protein conserved in bacteria
G6536_13260	COG0439	Biotin carboxylase
G6536_13265	COG0511	ligase activity, forming carbon-carbon bonds
G6536_13305	COG3854	ATPases associated with a variety of cellular activities
G6536_13315	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G6536_13320	COG0006	proline dipeptidase activity
G6536_13325	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G6536_13335	COG3872	metal-dependent enzyme
G6536_13345	COG1752	Esterase of the alpha-beta hydrolase superfamily
G6536_13350	COG1321	iron dependent repressor
G6536_13355	COG0095	Lipoate-protein ligase
G6536_13360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G6536_13365	COG2113	Glycine betaine
G6536_13370	COG4176	ABC-type proline glycine betaine transport system permease component
G6536_13375	COG0517	IMP dehydrogenase activity
G6536_13375	COG4175	Glycine betaine
G6536_13380	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G6536_13385	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G6536_13390	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G6536_13395	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G6536_13420	COG0681	Belongs to the peptidase S26 family
G6536_13445	COG4940	Competence protein ComGF
G6536_13455	COG4970	Tfp pilus assembly protein FimT
G6536_13460	COG4537	Required for transformation and DNA binding
G6536_13465	COG1459	type II secretion system
G6536_13470	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G6536_13475	COG1366	Belongs to the anti-sigma-factor antagonist family
G6536_13485	COG1393	Belongs to the ArsC family
G6536_13495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6536_13505	COG0011	TIGRFAM Protein of
G6536_13515	COG2866	Carboxypeptidase
G6536_13520	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G6536_13530	COG1368	sulfuric ester hydrolase activity
G6536_13535	COG1940	carbohydrate kinase activity
G6536_13540	COG4483	Protein conserved in bacteria
G6536_13545	COG0697	spore germination
G6536_13550	COG0457	Tetratricopeptide repeat
G6536_13550	COG0705	Rhomboid family
G6536_13560	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G6536_13565	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G6536_13570	COG0438	transferase activity, transferring glycosyl groups
G6536_13585	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G6536_13590	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G6536_13595	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G6536_13600	COG0581	inorganic phosphate transmembrane transporter activity
G6536_13605	COG0573	inorganic phosphate transmembrane transporter activity
G6536_13610	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G6536_13615	COG0768	penicillin binding
G6536_13620	COG0477	Major facilitator Superfamily
G6536_13625	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G6536_13630	COG2839	Protein conserved in bacteria
G6536_13635	COG5521	maltodextrose utilization protein MalA
G6536_13640	COG1388	LysM domain
G6536_13645	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
G6536_13650	COG4709	membrane
G6536_13655	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
G6536_13660	COG0735	belongs to the Fur family
G6536_13665	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G6536_13670	COG1121	(ABC) transporter
G6536_13675	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G6536_13685	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
G6536_13690	COG0513	Belongs to the DEAD box helicase family
G6536_13700	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
G6536_13705	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G6536_13710	COG2384	SAM-dependent methyltransferase
G6536_13775	COG2010	Cytochrome c
G6536_13780	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G6536_13785	COG0358	DNA primase activity
G6536_13790	COG1671	Belongs to the UPF0178 family
G6536_13795	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
G6536_13800	COG0517	IMP dehydrogenase activity
G6536_13805	COG0751	glycine-tRNA ligase activity
G6536_13810	COG0752	glycyl-tRNA synthetase alpha subunit
G6536_13815	COG1381	Involved in DNA repair and RecF pathway recombination
G6536_13825	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G6536_13830	COG0295	cytidine deaminase activity
G6536_13835	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
G6536_13840	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G6536_13845	COG1480	7TM receptor with intracellular HD hydrolase
G6536_13850	COG1702	phosphate starvation-inducible protein PhoH
G6536_13855	COG0561	phosphatase activity
G6536_13870	COG4864	UPF0365 protein
G6536_13875	COG1030	water channel activity
G6536_13880	COG1610	YqeY-like protein
G6536_13885	COG0828	Belongs to the bacterial ribosomal protein bS21 family
G6536_13890	COG1283	sodium-dependent phosphate transmembrane transporter activity
G6536_13895	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
G6536_13900	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G6536_13905	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G6536_13910	COG2264	protein methyltransferase activity
G6536_13915	COG0484	heat shock protein binding
G6536_13920	COG0443	Heat shock 70 kDa protein
G6536_13925	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G6536_13930	COG1420	regulation of RNA biosynthetic process
G6536_13935	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G6536_13940	COG0481	GTPase activity
G6536_13950	COG0860	N-Acetylmuramoyl-L-alanine amidase
G6536_13960	COG0268	Binds directly to 16S ribosomal RNA
G6536_13965	COG1466	dna polymerase III delta subunit
G6536_13975	COG0658	competence protein
G6536_13975	COG2333	competence protein COMEC
G6536_13980	COG2131	deaminase
G6536_13985	COG1555	photosystem II stabilization
G6536_13985	COG1596	polysaccharide export
G6536_13990	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G6536_13995	COG2226	methyltransferase
G6536_14000	COG0799	negative regulation of ribosome biogenesis
G6536_14005	COG1713	HD superfamily hydrolase involved in NAD metabolism
G6536_14010	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G6536_14015	COG1534	Rna-binding protein
G6536_14020	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G6536_14025	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
G6536_14030	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
G6536_14045	COG2755	lipolytic protein G-D-S-L family
G6536_14050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G6536_14055	COG5609	conserved protein (DUF2294)
G6536_14060	COG3383	formate dehydrogenase (NAD+) activity
G6536_14065	COG2427	Protein of unknown function (DUF1641)
G6536_14085	COG0457	Tetratricopeptide repeat
G6536_14090	COG5444	nuclease activity
G6536_14120	COG1793	dna ligase
G6536_14215	COG0629	single-stranded DNA binding
G6536_14260	COG0739	heme binding
G6536_14385	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
G6536_14485	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G6536_14520	COG0300	oxidoreductase activity
G6536_14525	COG1902	pentaerythritol trinitrate reductase activity
G6536_14530	COG0596	Alpha beta hydrolase
G6536_14530	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6536_14535	COG1309	transcriptional regulator
G6536_14545	COG1063	alcohol dehydrogenase
G6536_14580	COG0860	N-Acetylmuramoyl-L-alanine amidase
G6536_14640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G6536_14640	COG0425	Belongs to the sulfur carrier protein TusA family
G6536_14650	COG2197	response regulator
G6536_14655	COG4585	Histidine kinase
G6536_14660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G6536_14665	COG0730	response to heat
G6536_14670	COG0425	Belongs to the sulfur carrier protein TusA family
G6536_14675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6536_14675	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G6536_14680	COG0425	Belongs to the sulfur carrier protein TusA family
G6536_14680	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G6536_14685	COG2210	Belongs to the sulfur carrier protein TusA family
G6536_14690	COG1937	Protein conserved in bacteria
G6536_14735	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G6536_14740	COG0113	porphobilinogen synthase activity
G6536_14745	COG0803	Belongs to the bacterial solute-binding protein 9 family
G6536_14750	COG1121	(ABC) transporter
G6536_14755	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G6536_14770	COG1942	4-Oxalocrotonate Tautomerase
G6536_14780	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
G6536_14790	COG1733	regulation of RNA biosynthetic process
G6536_14795	COG3239	Fatty acid desaturase
G6536_14800	COG4585	Histidine kinase
G6536_14805	COG2197	response regulator
G6536_14810	COG0492	ferredoxin-NADP+ reductase activity
G6536_14815	COG0747	negative chemotaxis
G6536_14820	COG0601	transmembrane transport
G6536_14825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6536_14830	COG0444	Belongs to the ABC transporter superfamily
G6536_14835	COG4608	Belongs to the ABC transporter superfamily
G6536_14855	COG1028	Short-chain dehydrogenase reductase Sdr
G6536_14870	COG2124	cytochrome p450
G6536_14875	COG0730	response to heat
G6536_14890	COG1028	Short-chain dehydrogenase reductase Sdr
G6536_14895	COG1621	beta-fructofuranosidase activity
G6536_14900	COG3716	PTS system mannose fructose sorbose family IID component
G6536_14905	COG3715	PTS system
G6536_14910	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G6536_14915	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
G6536_14920	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
G6536_14920	COG3933	PFAM sigma-54 factor interaction domain-containing protein
G6536_14940	COG2169	Transcriptional regulator
G6536_14945	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G6536_14950	COG0656	L-ascorbic acid biosynthetic process
G6536_14955	COG2814	Major facilitator Superfamily
G6536_14960	COG1733	regulation of RNA biosynthetic process
G6536_14965	COG3340	Belongs to the peptidase S51 family
G6536_14970	COG1587	Uroporphyrinogen-III synthase
G6536_14980	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G6536_14985	COG0583	DNA-binding transcription factor activity
G6536_14990	COG2814	Major facilitator Superfamily
G6536_15000	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G6536_15000	COG2124	cytochrome p450
G6536_15005	COG1309	transcriptional regulator
G6536_15010	COG1404	Belongs to the peptidase S8 family
G6536_15015	COG2226	methyltransferase
G6536_15040	COG0626	cystathionine gamma-synthase activity
G6536_15045	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G6536_15050	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
G6536_15055	COG2226	methyltransferase
G6536_15070	COG0768	penicillin binding
G6536_15075	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G6536_15080	COG0572	uridine kinase
G6536_15085	COG0826	peptidase U32
G6536_15090	COG0826	peptidase U32
G6536_15095	COG4122	O-methyltransferase activity
G6536_15100	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G6536_15105	COG3906	Belongs to the UPF0473 family
G6536_15110	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G6536_15115	COG4472	Bacterial protein of unknown function (DUF965)
G6536_15120	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G6536_15125	COG0628	permease
G6536_15140	COG3881	PFAM PRC-barrel domain
G6536_15145	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G6536_15150	COG0457	Tetratricopeptide repeat
G6536_15155	COG0482	sulfurtransferase activity
G6536_15160	COG1104	cysteine desulfurase activity
G6536_15165	COG1959	2 iron, 2 sulfur cluster binding
G6536_15170	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G6536_15175	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
G6536_15185	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G6536_15190	COG0124	histidyl-tRNA synthetase
G6536_15200	COG3103	Sh3 type 3 domain protein
G6536_15200	COG4991	sh3 domain protein
G6536_15200	COG0860	N-Acetylmuramoyl-L-alanine amidase
G6536_15205	COG1490	D-aminoacyl-tRNA deacylase activity
G6536_15210	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G6536_15215	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G6536_15220	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
G6536_15220	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G6536_15225	COG5416	Lipopolysaccharide assembly protein A domain
G6536_15230	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G6536_15230	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G6536_15240	COG2244	polysaccharide biosynthetic process
G6536_15245	COG2323	membrane
G6536_15255	COG1862	Preprotein translocase
G6536_15260	COG0343	queuine tRNA-ribosyltransferase activity
G6536_15265	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
G6536_15275	COG2255	four-way junction helicase activity
G6536_15280	COG0632	four-way junction helicase activity
G6536_15290	COG2112	serine threonine protein kinase
G6536_15300	COG2318	DinB family
G6536_15305	COG4195	phage-related replication protein
G6536_15320	COG0217	transcriptional regulatory protein
G6536_15330	COG1388	LysM domain
G6536_15335	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
G6536_15340	COG0157	Belongs to the NadC ModD family
G6536_15345	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
G6536_15350	COG1104	cysteine desulfurase activity
G6536_15355	COG1827	regulation of RNA biosynthetic process
G6536_15360	COG0077	Prephenate dehydratase
G6536_15365	COG4492	Belongs to the UPF0735 family
G6536_15370	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G6536_15375	COG3290	protein histidine kinase activity
G6536_15380	COG0211	Belongs to the bacterial ribosomal protein bL27 family
G6536_15385	COG2868	ribosomal protein
G6536_15390	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G6536_15395	COG1994	Peptidase M50
G6536_15400	COG0739	heme binding
G6536_15405	COG3832	glyoxalase III activity
G6536_15410	COG0640	Transcriptional regulator
G6536_15415	COG2894	cell division
G6536_15420	COG0850	regulation of cytokinetic process
G6536_15425	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
G6536_15435	COG1077	Cell shape determining protein MreB Mrl
G6536_15440	COG2003	Belongs to the UPF0758 family
G6536_15445	COG0424	maF-like protein
G6536_15455	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
G6536_15460	COG0285	dihydrofolate synthase activity
G6536_15465	COG0525	valine-tRNA ligase activity
G6536_15475	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G6536_15480	COG1388	LysM domain
G6536_15485	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G6536_15490	COG0113	porphobilinogen synthase activity
G6536_15495	COG1587	Uroporphyrinogen-III synthase
G6536_15500	COG0181	hydroxymethylbilane synthase activity
G6536_15505	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G6536_15510	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
G6536_15520	COG0218	Necessary for normal cell division and for the maintenance of normal septation
G6536_15525	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G6536_15530	COG0470	DNA polymerase III
G6536_15530	COG1067	ATP-dependent peptidase activity
G6536_15535	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G6536_15540	COG0544	peptidyl-prolyl cis-trans isomerase activity
G6536_15545	COG0457	Tetratricopeptide repeat
G6536_15545	COG1477	protein flavinylation
G6536_15550	COG0066	3-isopropylmalate dehydratase activity
G6536_15555	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G6536_15560	COG0473	3-isopropylmalate dehydrogenase activity
G6536_15565	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G6536_15570	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G6536_15575	COG0440	acetolactate synthase activity
G6536_15580	COG0028	Belongs to the TPP enzyme family
G6536_15585	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G6536_15615	COG5518	Phage portal protein
G6536_15655	COG5444	nuclease activity
G6536_15660	COG0457	Tetratricopeptide repeat
G6536_15685	COG0622	Phosphoesterase
G6536_15690	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G6536_15695	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
G6536_15700	COG5401	PFAM Sporulation and spore germination
G6536_15705	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G6536_15710	COG1846	Transcriptional regulator
G6536_15715	COG2197	response regulator
G6536_15720	COG4221	oxidoreductase activity
G6536_15725	COG0824	Thioesterase
G6536_15730	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G6536_15735	COG1053	succinate dehydrogenase
G6536_15740	COG2009	succinate dehydrogenase
G6536_15745	COG1719	4-vinyl reductase, 4VR
G6536_15750	COG0527	aspartate kinase activity
G6536_15755	COG0322	excinuclease ABC activity
G6536_15760	COG3118	belongs to the thioredoxin family
G6536_15765	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
G6536_15770	COG2086	electron transfer activity
G6536_15775	COG1024	Enoyl-CoA hydratase
G6536_15780	COG1309	transcriptional regulator
G6536_15785	COG0318	PFAM AMP-dependent synthetase and ligase
G6536_15790	COG3766	membrane
G6536_15795	COG1193	negative regulation of DNA recombination
G6536_15800	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
G6536_15800	COG1796	DNA polymerase
G6536_15805	COG1286	toxin biosynthetic process
G6536_15810	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
G6536_15815	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G6536_15825	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G6536_15825	COG0072	phenylalanine-tRNA ligase activity
G6536_15840	COG1137	ATPase activity
G6536_15855	COG0072	phenylalanine-tRNA ligase activity
G6536_15855	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G6536_15860	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G6536_15865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G6536_15875	COG1966	Carbon starvation protein
G6536_15890	COG0395	ABC-type sugar transport system, permease component
G6536_15895	COG1175	transmembrane transport
G6536_15900	COG1653	transport
G6536_15905	COG0371	Dehydrogenase
G6536_15910	COG0235	Class ii aldolase
G6536_15915	COG1069	ribulokinase activity
G6536_15920	COG2160	L-arabinose isomerase activity
G6536_15925	COG3507	Belongs to the glycosyl hydrolase 43 family
G6536_15930	COG1363	Peptidase, m42
G6536_15940	COG3326	Membrane
G6536_15945	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G6536_15950	COG0291	Belongs to the bacterial ribosomal protein bL35 family
G6536_15955	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
G6536_15960	COG1346	cytolysis
G6536_15970	COG3540	Alkaline phosphatase
G6536_15975	COG3279	Response regulator of the LytR AlgR family
G6536_15980	COG3275	phosphorelay sensor kinase activity
G6536_15990	COG1011	Hydrolase
G6536_15995	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G6536_16005	COG0398	Pfam SNARE associated Golgi protein
G6536_16010	COG1484	DNA-dependent DNA replication
G6536_16015	COG3611	Membrane attachment protein
G6536_16020	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G6536_16035	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
G6536_16040	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G6536_16045	COG3866	Pectate lyase
G6536_16050	COG0237	dephospho-CoA kinase activity
G6536_16055	COG1971	Probably functions as a manganese efflux pump
G6536_16060	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G6536_16065	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G6536_16065	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G6536_16070	COG5002	protein histidine kinase activity
G6536_16075	COG0745	RESPONSE REGULATOR receiver
G6536_16080	COG0039	L-malate dehydrogenase activity
G6536_16085	COG0538	isocitrate dehydrogenase activity
G6536_16090	COG0372	Belongs to the citrate synthase family
G6536_16095	COG2707	UPF0756 membrane protein
G6536_16100	COG0628	permease
G6536_16105	COG3030	protein affecting phage T7 exclusion by the F plasmid
G6536_16115	COG0205	6-phosphofructokinase activity
G6536_16120	COG0825	malonyl-CoA metabolic process
G6536_16125	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G6536_16130	COG0281	malic enzyme
G6536_16135	COG0587	DNA-directed DNA polymerase activity
G6536_16155	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G6536_16165	COG4109	DRTGG domain
G6536_16170	COG1695	Transcriptional regulator
G6536_16175	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
G6536_16180	COG1028	Short-chain dehydrogenase reductase Sdr
G6536_16190	COG0165	Argininosuccinate lyase
G6536_16195	COG0137	argininosuccinate synthase activity
G6536_16200	COG0521	Mo-molybdopterin cofactor biosynthetic process
G6536_16205	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G6536_16210	COG0827	DNA restriction-modification system
G6536_16215	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
G6536_16220	COG3874	Sporulation protein YtfJ
G6536_16230	COG1714	RDD family
G6536_16235	COG0616	signal peptide processing
G6536_16240	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G6536_16245	COG1566	PFAM secretion protein HlyD family protein
G6536_16260	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G6536_16270	COG0301	tRNA thio-modification
G6536_16275	COG1104	cysteine desulfurase activity
G6536_16280	COG1114	Component of the transport system for branched-chain amino acids
G6536_16290	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
G6536_16295	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
G6536_16300	COG1309	transcriptional regulator
G6536_16305	COG1956	GAF domain-containing protein
G6536_16310	COG2199	diguanylate cyclase activity
G6536_16310	COG2203	Gaf domain
G6536_16315	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G6536_16330	COG3152	Membrane
G6536_16335	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
G6536_16340	COG1522	sequence-specific DNA binding
G6536_16350	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G6536_16355	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G6536_16360	COG0454	-acetyltransferase
G6536_16365	COG0517	IMP dehydrogenase activity
G6536_16370	COG0123	including yeast histone deacetylase and acetoin utilization protein
G6536_16375	COG1360	Flagellar Motor Protein
G6536_16380	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G6536_16385	COG1609	Transcriptional regulator
G6536_16390	COG1605	Chorismate mutase
G6536_16390	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
G6536_16400	COG3118	belongs to the thioredoxin family
G6536_16405	COG4980	gas vesicle protein
G6536_16410	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
G6536_16415	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G6536_16420	COG1674	ftsk spoiiie
G6536_16425	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G6536_16430	COG4848	Belongs to the UPF0354 family
G6536_16435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G6536_16445	COG1363	Peptidase, m42
G6536_16450	COG5584	Small secreted protein
G6536_16455	COG0281	malic enzyme
G6536_16460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6536_16470	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G6536_16480	COG0510	thiamine kinase activity
G6536_16485	COG1523	belongs to the glycosyl hydrolase 13 family
G6536_16490	COG1597	lipid kinase activity
G6536_16500	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
G6536_16505	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G6536_16520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G6536_16525	COG2252	PERMEase
G6536_16530	COG1349	DNA-binding transcription factor activity
G6536_16535	COG1187	pseudouridine synthase activity
G6536_16540	COG2244	polysaccharide biosynthetic process
G6536_16545	COG2081	HI0933 family
G6536_16550	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G6536_16560	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G6536_16575	COG5578	integral membrane protein
G6536_16580	COG0673	inositol 2-dehydrogenase activity
G6536_16585	COG1653	transport
G6536_16590	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
G6536_16595	COG4209	transmembrane transport
G6536_16600	COG2207	Transcriptional regulator
G6536_16605	COG1653	transport
G6536_16610	COG0395	ABC-type sugar transport system, permease component
G6536_16615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G6536_16620	COG1073	alpha beta
G6536_16630	COG0583	DNA-binding transcription factor activity
G6536_16635	COG0346	lactoylglutathione lyase activity
G6536_16640	COG0495	leucyl-tRNA aminoacylation
G6536_16650	COG2814	Major facilitator Superfamily
G6536_16660	COG2433	Pfam Transposase IS66
G6536_16665	COG0577	efflux transmembrane transporter activity
G6536_16670	COG1136	(ABC) transporter
G6536_16680	COG1131	(ABC) transporter
G6536_16685	COG1725	Transcriptional regulator
G6536_16695	COG1242	4 iron, 4 sulfur cluster binding
G6536_16700	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
G6536_16705	COG1301	dicarboxylic acid transport
G6536_16715	COG2267	carboxylic ester hydrolase activity
G6536_16720	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
G6536_16725	COG0671	phosphoesterase, PA-phosphatase related
G6536_16730	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G6536_16730	COG0438	transferase activity, transferring glycosyl groups
G6536_16735	COG0367	asparagine synthase
G6536_16740	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G6536_16745	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
G6536_16750	COG1301	dicarboxylic acid transport
G6536_16760	COG1506	peptidase
G6536_16765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G6536_16770	COG1116	anion transmembrane transporter activity
G6536_16775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6536_16780	COG0494	nUDIX hydrolase
G6536_16790	COG4824	toxin secretion phage lysis holin
G6536_16795	COG0783	Belongs to the Dps family
G6536_16810	COG1854	S-ribosylhomocysteine lyase activity
G6536_16815	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G6536_16820	COG0288	reversible hydration of carbon dioxide
G6536_16825	COG0523	cobalamin synthesis protein
G6536_16830	COG0803	Belongs to the bacterial solute-binding protein 9 family
G6536_16835	COG0254	rRNA binding
G6536_16840	COG1271	oxidase subunit
G6536_16845	COG1294	oxidase, subunit
G6536_16860	COG4948	Mandelate Racemase Muconate Lactonizing
G6536_16865	COG0318	PFAM AMP-dependent synthetase and ligase
G6536_16870	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G6536_16875	COG0596	Alpha beta hydrolase
G6536_16880	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
G6536_16885	COG1169	isochorismate synthase
G6536_16890	COG1575	Belongs to the MenA family. Type 1 subfamily
G6536_16895	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G6536_16900	COG0058	SHG alpha-glucan phosphorylase activity
G6536_16905	COG0297	glycogen (starch) synthase activity
G6536_16910	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G6536_16915	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G6536_16920	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G6536_17045	COG1609	Transcriptional regulator
G6536_17050	COG3859	Proton-coupled thiamine transporter YuaJ
G6536_17055	COG3764	Sortase (surface protein transpeptidase)
G6536_17070	COG0457	Tetratricopeptide repeat
G6536_17075	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
G6536_17080	COG0569	domain protein
G6536_17085	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G6536_17095	COG2318	DinB family
G6536_17105	COG1454	alcohol dehydrogenase
G6536_17110	COG1012	belongs to the aldehyde dehydrogenase family
G6536_17115	COG1510	regulation of RNA biosynthetic process
G6536_17125	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6536_17130	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G6536_17135	COG2140	Oxalate decarboxylase
G6536_17145	COG1397	ADP-ribosylglycohydrolase
G6536_17180	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
G6536_17195	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G6536_17200	COG0726	polysaccharide deacetylase
G6536_17205	COG1408	metallophosphoesterase
G6536_17210	COG1968	undecaprenyl-diphosphatase activity
G6536_17215	COG0628	permease
G6536_17220	COG0673	inositol 2-dehydrogenase activity
G6536_17225	COG0693	protein deglycase activity
G6536_17230	COG0840	transmembrane signaling receptor activity
G6536_17235	COG0840	transmembrane signaling receptor activity
G6536_17240	COG0840	transmembrane signaling receptor activity
G6536_17250	COG2070	2-Nitropropane dioxygenase
G6536_17255	COG0432	Pfam Uncharacterised protein family UPF0047
G6536_17260	COG0366	Alpha amylase catalytic
G6536_17275	COG5297	Belongs to the glycosyl hydrolase family 6
G6536_17280	COG1253	flavin adenine dinucleotide binding
G6536_17285	COG2738	Putative neutral zinc metallopeptidase
G6536_17300	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G6536_17310	COG2323	membrane
G6536_17315	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
G6536_17325	COG0166	Belongs to the GPI family
G6536_17330	COG1979	alcohol dehydrogenase
G6536_17335	COG2155	Conserved Protein
G6536_17340	COG1098	S1 RNA binding domain
G6536_17345	COG0436	Aminotransferase
G6536_17350	COG1522	sequence-specific DNA binding
G6536_17355	COG2267	carboxylic ester hydrolase activity
G6536_17370	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
G6536_17385	COG5018	Exonuclease
G6536_17390	COG2814	Major facilitator Superfamily
G6536_17395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G6536_17400	COG3011	Protein conserved in bacteria
G6536_17410	COG3290	protein histidine kinase activity
G6536_17415	COG4565	transcriptional regulatory protein
G6536_17425	COG1183	phosphatidylcholine synthase activity
G6536_17430	COG0586	Pfam SNARE associated Golgi protein
G6536_17435	COG0688	phosphatidylethanolamine metabolic process
G6536_17440	COG3493	citrate carrier protein
G6536_17450	COG2111	Na H antiporter
G6536_17450	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G6536_17455	COG2111	Na H antiporter
G6536_17460	COG1006	Multisubunit Na H antiporter MnhC subunit
G6536_17465	COG0651	ATP synthesis coupled electron transport
G6536_17470	COG1863	multisubunit Na H antiporter MnhE subunit
G6536_17475	COG2212	antiporter activity
G6536_17480	COG1320	monovalent cation:proton antiporter activity
G6536_17485	COG2050	protein possibly involved in aromatic compounds catabolism
G6536_17490	COG2197	response regulator
G6536_17495	COG4585	Histidine kinase
G6536_17525	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
G6536_17530	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
G6536_17535	COG1335	isochorismatase
G6536_17540	COG5506	Protein of unknown function (DUF1694)
G6536_17555	COG0628	permease
G6536_17560	COG1959	2 iron, 2 sulfur cluster binding
G6536_17565	COG0657	acetylesterase activity
G6536_17575	COG1418	mRNA catabolic process
G6536_17580	COG1028	Short-chain dehydrogenase reductase Sdr
G6536_17590	COG1511	domain protein
G6536_17595	COG0433	COG0433 Predicted ATPase
G6536_17595	COG1674	ftsk spoiiie
G6536_17600	COG4499	WXG100 protein secretion system (Wss), protein YukC
G6536_17605	COG5417	Belongs to the EsaB family
G6536_17610	COG4842	Belongs to the WXG100 family
G6536_17615	COG1115	amino acid carrier protein
G6536_17620	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
G6536_17620	COG2508	Transcriptional regulator
G6536_17625	COG0686	Belongs to the AlaDH PNT family
G6536_17635	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G6536_17640	COG1268	BioY protein
G6536_17645	COG2056	Na+-H+ antiporter family
G6536_17650	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G6536_17655	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
G6536_17660	COG3584	3D domain protein
G6536_17675	COG1252	NADH dehydrogenase
G6536_17680	COG0492	ferredoxin-NADP+ reductase activity
G6536_17695	COG0456	acetyltransferase
G6536_17700	COG0316	Belongs to the HesB IscA family
G6536_17705	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
G6536_17710	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G6536_17715	COG4844	belongs to the
G6536_17720	COG1252	NADH dehydrogenase
G6536_17725	COG5646	InterPro IPR014922
G6536_17735	COG0457	Tetratricopeptide repeat
G6536_17740	COG3479	Phenolic acid decarboxylase
G6536_17750	COG4837	Protein of unknown function (DUF1462)
G6536_17755	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
G6536_17760	COG0823	Involved in the tonB-independent uptake of proteins
G6536_17760	COG4946	Tricorn protease homolog
G6536_17760	COG1506	peptidase
G6536_17765	COG0083	homoserine kinase activity
G6536_17770	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G6536_17775	COG0460	homoserine dehydrogenase
G6536_17785	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G6536_17790	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
G6536_17800	COG0647	UMP catabolic process
G6536_17805	COG2445	Protein of unknown function DUF86
G6536_17810	COG4470	Protein conserved in bacteria
G6536_17825	COG0739	heme binding
G6536_17835	COG0733	neurotransmitter:sodium symporter activity
G6536_17845	COG3377	Domain of unknown function (DUF1805)
G6536_17850	COG0737	Belongs to the 5'-nucleotidase family
G6536_17855	COG0730	response to heat
G6536_17860	COG1801	Protein of unknown function DUF72
G6536_17870	COG3226	Transcriptional regulator
G6536_17880	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
G6536_17885	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G6536_17890	COG2508	Transcriptional regulator
G6536_17895	COG2814	Major facilitator Superfamily
G6536_17900	COG1288	antiporter activity
G6536_17910	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G6536_17915	COG2356	endonuclease I
G6536_17925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6536_17940	COG0457	Tetratricopeptide repeat
G6536_17945	COG0719	Fe-S assembly protein
G6536_17950	COG0822	iron-sulfur transferase activity
G6536_17955	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G6536_17960	COG0719	Fe-S assembly protein
G6536_17965	COG0396	ATPase activity
G6536_17975	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G6536_17980	COG1464	Belongs to the NlpA lipoprotein family
G6536_17985	COG2011	ABC-type metal ion transport system permease component
G6536_17990	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G6536_18000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G6536_18005	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
G6536_18015	COG0509	glycine decarboxylation via glycine cleavage system
G6536_18020	COG1393	Belongs to the ArsC family
G6536_18025	COG1960	acyl-CoA dehydrogenase activity
G6536_18030	COG0183	Belongs to the thiolase family
G6536_18035	COG1024	Enoyl-CoA hydratase
G6536_18035	COG1250	3-hydroxyacyl-CoA dehydrogenase
G6536_18050	COG5577	PFAM Coat F domain
G6536_18065	COG1120	ATPase activity
G6536_18070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G6536_18075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G6536_18080	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G6536_18095	COG1686	Belongs to the peptidase S11 family
G6536_18100	COG1028	Short-chain dehydrogenase reductase Sdr
G6536_18105	COG0783	Belongs to the Dps family
G6536_18110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6536_18115	COG0745	RESPONSE REGULATOR receiver
G6536_18120	COG2205	protein histidine kinase activity
G6536_18120	COG2770	Histidine kinase
G6536_18130	COG1309	transcriptional regulator
G6536_18135	COG0114	fumarate hydratase activity
G6536_18145	COG0697	spore germination
G6536_18150	COG0814	amino acid
G6536_18165	COG2197	response regulator
G6536_18170	COG4585	Histidine kinase
G6536_18175	COG4758	membrane
G6536_18185	COG1842	Phage shock protein A
G6536_18190	COG4758	membrane
G6536_18195	COG4677	pectinesterase activity
G6536_18200	COG2096	Adenosyltransferase
G6536_18205	COG1028	Short-chain dehydrogenase reductase Sdr
G6536_18215	COG1454	alcohol dehydrogenase
G6536_18220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6536_18225	COG1120	ATPase activity
G6536_18230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G6536_18235	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G6536_18240	COG1802	Transcriptional regulator
G6536_18245	COG1028	Short-chain dehydrogenase reductase Sdr
G6536_18250	COG2258	MOSC domain
G6536_18255	COG0583	DNA-binding transcription factor activity
G6536_18265	COG2721	sulfolactate sulfo-lyase activity
G6536_18270	COG0246	Mannitol dehydrogenase
G6536_18275	COG1609	Transcriptional regulator
G6536_18280	COG2211	Major facilitator Superfamily
G6536_18285	COG1904	glucuronate isomerase
G6536_18290	COG2205	protein histidine kinase activity
G6536_18295	COG0745	RESPONSE REGULATOR receiver
G6536_18300	COG1120	ATPase activity
G6536_18305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G6536_18310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G6536_18315	COG0531	amino acid
G6536_18325	COG1988	membrane-bound metal-dependent
G6536_18330	COG1368	sulfuric ester hydrolase activity
G6536_18335	COG2814	Major facilitator Superfamily
G6536_18340	COG0656	L-ascorbic acid biosynthetic process
G6536_18345	COG1940	carbohydrate kinase activity
G6536_18360	COG3973	AAA domain
G6536_18365	COG2860	membrane
G6536_18370	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
G6536_18370	COG0456	acetyltransferase
G6536_18375	COG0456	acetyltransferase
G6536_18380	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
G6536_18385	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G6536_18390	COG2217	Heavy metal translocating P-type atpase
G6536_18395	COG1653	transport
G6536_18400	COG1175	transmembrane transport
G6536_18405	COG0395	ABC-type sugar transport system, permease component
G6536_18415	COG1472	Belongs to the glycosyl hydrolase 3 family
G6536_18420	COG1121	(ABC) transporter
G6536_18425	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G6536_18430	COG0803	Belongs to the bacterial solute-binding protein 9 family
G6536_18450	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
G6536_18450	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
G6536_18455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G6536_18455	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G6536_18455	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G6536_18475	COG2217	Heavy metal translocating P-type atpase
G6536_18480	COG2608	mercury ion transmembrane transporter activity
G6536_18485	COG1937	Protein conserved in bacteria
G6536_18490	COG0693	protein deglycase activity
G6536_18495	COG1349	DNA-binding transcription factor activity
G6536_18500	COG1070	Carbohydrate kinase
G6536_18505	COG4952	isomerase
G6536_18515	COG1028	Short-chain dehydrogenase reductase Sdr
G6536_18515	COG3347	Dehydrogenase
G6536_18525	COG2814	Major facilitator Superfamily
G6536_18535	COG2124	cytochrome p450
G6536_18545	COG1846	Transcriptional regulator
G6536_18555	COG0673	inositol 2-dehydrogenase activity
G6536_18560	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G6536_18565	COG1054	Belongs to the UPF0176 family
G6536_18575	COG1191	sigma factor activity
G6536_18585	COG2140	Oxalate decarboxylase
G6536_18615	COG5444	nuclease activity
G6536_18645	COG2323	membrane
G6536_18650	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
G6536_18655	COG0662	Cupin 2, conserved barrel domain protein
G6536_18695	COG1705	Flagellar rod assembly protein muramidase FlgJ
G6536_18705	COG3953	SLT domain
G6536_18705	COG5280	Phage tail tape measure protein TP901
G6536_18765	COG1802	Transcriptional regulator
G6536_18765	COG4626	Terminase
G6536_18905	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G6536_18910	COG0557	exoribonuclease II activity
G6536_18915	COG1647	Serine aminopeptidase, S33
G6536_18920	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G6536_18925	COG2002	toxin-antitoxin pair type II binding
G6536_18930	COG1476	TRANSCRIPTIONal
G6536_18935	COG1396	sequence-specific DNA binding
G6536_18940	COG1396	sequence-specific DNA binding
G6536_18945	COG1174	glycine betaine transport
G6536_18950	COG1732	Glycine betaine
G6536_18955	COG1174	glycine betaine transport
G6536_18960	COG0517	IMP dehydrogenase activity
G6536_18960	COG1125	glycine betaine transport
G6536_18965	COG1510	regulation of RNA biosynthetic process
G6536_18970	COG2095	MarC family integral membrane protein
G6536_18975	COG3064	Membrane
G6536_18985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G6536_19005	COG0148	phosphopyruvate hydratase activity
G6536_19010	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
G6536_19015	COG0149	triose-phosphate isomerase activity
G6536_19020	COG0126	phosphoglycerate kinase activity
G6536_19025	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G6536_19030	COG2390	Transcriptional regulator
G6536_19035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6536_19040	COG1113	amino acid transport
G6536_19060	COG1556	Lactate utilization protein
G6536_19065	COG1139	Iron-sulfur cluster binding protein
G6536_19070	COG0247	lactate metabolic process
G6536_19075	COG2186	Transcriptional regulator
G6536_19080	COG1620	l-lactate permease
G6536_19085	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
G6536_19095	COG5039	Polysaccharide pyruvyl transferase
G6536_19100	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G6536_19105	COG0110	maltose O-acetyltransferase activity
G6536_19110	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G6536_19115	COG2244	polysaccharide biosynthetic process
G6536_19120	COG1216	Glycosyl transferase, family 2
G6536_19125	COG5039	Polysaccharide pyruvyl transferase
G6536_19130	COG1216	Glycosyl transferase, family 2
G6536_19140	COG0438	transferase activity, transferring glycosyl groups
G6536_19145	COG1215	transferase activity, transferring glycosyl groups
G6536_19150	COG0438	transferase activity, transferring glycosyl groups
G6536_19155	COG1086	Polysaccharide biosynthesis protein
G6536_19160	COG0489	protein tyrosine kinase activity
G6536_19165	COG3944	biosynthesis protein
G6536_19170	COG1396	sequence-specific DNA binding
G6536_19180	COG2249	NAD(P)H dehydrogenase (quinone) activity
G6536_19185	COG2271	Major facilitator Superfamily
G6536_19195	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
G6536_19210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6536_19220	COG1733	regulation of RNA biosynthetic process
G6536_19225	COG1902	pentaerythritol trinitrate reductase activity
G6536_19230	COG1621	beta-fructofuranosidase activity
G6536_19235	COG1621	beta-fructofuranosidase activity
G6536_19250	COG0740	serine-type endopeptidase activity
G6536_19255	COG1611	Belongs to the LOG family
G6536_19260	COG1694	Mazg nucleotide pyrophosphohydrolase
G6536_19265	COG1078	dGTPase activity
G6536_19270	COG0659	secondary active sulfate transmembrane transporter activity
G6536_19275	COG0288	reversible hydration of carbon dioxide
G6536_19280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G6536_19285	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G6536_19290	COG0640	Transcriptional regulator
G6536_19300	COG2732	(Barnase) inhibitor
G6536_19305	COG2162	N-hydroxyarylamine O-acetyltransferase activity
G6536_19310	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G6536_19315	COG1481	regulation of sporulation
G6536_19320	COG0391	Required for morphogenesis under gluconeogenic growth conditions
G6536_19325	COG1660	Displays ATPase and GTPase activities
G6536_19330	COG1051	belongs to the nudix hydrolase family
G6536_19340	COG0492	ferredoxin-NADP+ reductase activity
G6536_19345	COG0457	Tetratricopeptide repeat
G6536_19350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G6536_19355	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G6536_19355	COG0140	phosphoribosyl-ATP diphosphatase activity
G6536_19360	COG0107	imidazoleglycerol-phosphate synthase activity
G6536_19365	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G6536_19370	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G6536_19375	COG0131	Imidazoleglycerol-phosphate dehydratase
G6536_19380	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G6536_19385	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G6536_19390	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
G6536_19395	COG4990	cell redox homeostasis
G6536_19400	COG5297	Belongs to the glycosyl hydrolase family 6
G6536_19405	COG0110	maltose O-acetyltransferase activity
G6536_19410	COG0546	phosphoglycolate phosphatase activity
G6536_19415	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
G6536_19420	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
G6536_19425	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
G6536_19430	COG1846	Transcriptional regulator
G6536_19435	COG2814	Major facilitator Superfamily
G6536_19440	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
G6536_19445	COG1950	PFAM Membrane protein of
G6536_19450	COG1983	PspC domain protein
G6536_19455	COG3595	metallopeptidase activity
G6536_19480	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G6536_19485	COG0556	nucleotide-excision repair
G6536_19490	COG4897	Protein conserved in bacteria
G6536_19500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6536_19510	COG3409	Peptidoglycan-binding domain 1 protein
G6536_19510	COG0793	Belongs to the peptidase S41A family
G6536_19515	COG0473	3-isopropylmalate dehydrogenase activity
G6536_19520	COG3883	PFAM NLP P60 protein
G6536_19520	COG0791	NLP P60 protein
G6536_19525	COG2177	Part of the ABC transporter FtsEX involved in
G6536_19530	COG2884	Cell division ATP-binding protein ftsE
G6536_19535	COG2010	Cytochrome c
G6536_19540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G6536_19550	COG0653	protein targeting
G6536_19555	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G6536_19570	COG1516	flagellar protein fliS
G6536_19575	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
G6536_19580	COG1334	flagellar protein FlaG
G6536_19585	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G6536_19590	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
G6536_19595	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
G6536_19605	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G6536_19610	COG1256	bacterial-type flagellum assembly
G6536_19610	COG4786	Flagellar basal body rod
G6536_19615	COG3418	PFAM FlgN family protein
G6536_19620	COG2747	anti-sigma28 factor FlgM
G6536_19630	COG1040	competence protein
G6536_19640	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
G6536_19645	COG1307	EDD domain protein, DegV family
G6536_19650	COG2197	response regulator
G6536_19655	COG4585	Histidine kinase
G6536_19660	COG1739	Uncharacterized protein family UPF0029
G6536_19665	COG1316	TRANSCRIPTIONal
G6536_19675	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G6536_19680	COG0438	transferase activity, transferring glycosyl groups
G6536_19685	COG1215	transferase activity, transferring glycosyl groups
G6536_19690	COG3206	protein involved in exopolysaccharide biosynthesis
G6536_19695	COG3307	-O-antigen
G6536_19700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G6536_19705	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G6536_19710	COG0297	glycogen (starch) synthase activity
G6536_19710	COG0438	transferase activity, transferring glycosyl groups
G6536_19715	COG2244	polysaccharide biosynthetic process
G6536_19725	COG0860	N-Acetylmuramoyl-L-alanine amidase
G6536_19725	COG2247	cell wall binding repeat
G6536_19730	COG2385	sporulation resulting in formation of a cellular spore
G6536_19730	COG2247	cell wall binding repeat
G6536_19740	COG1316	TRANSCRIPTIONal
G6536_19745	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
G6536_19750	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G6536_19755	COG1134	teichoic acid transport
G6536_19760	COG1682	transport, permease protein
G6536_19775	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
G6536_19800	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
G6536_19805	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
G6536_19810	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
G6536_19815	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
G6536_19820	COG4193	domain, Protein
G6536_19825	COG1482	cell wall glycoprotein biosynthetic process
G6536_19845	COG0800	Aldolase
G6536_19850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6536_19855	COG1609	Transcriptional regulator
G6536_19860	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
G6536_19865	COG1028	Short-chain dehydrogenase reductase Sdr
G6536_19870	COG1063	alcohol dehydrogenase
G6536_19875	COG2814	Major facilitator Superfamily
G6536_19880	COG1316	TRANSCRIPTIONal
G6536_19885	COG0561	phosphatase activity
G6536_19890	COG0791	NLP P60 protein
G6536_19900	COG2843	Capsule synthesis protein
G6536_19910	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G6536_19915	COG1609	Transcriptional regulator
G6536_19920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6536_19925	COG1869	D-ribose catabolic process
G6536_19930	COG1129	ABC transporter
G6536_19935	COG1172	Belongs to the binding-protein-dependent transport system permease family
G6536_19940	COG1879	ABC-type sugar transport system periplasmic component
G6536_19950	COG3527	Alpha-acetolactate decarboxylase
G6536_19955	COG0028	Belongs to the TPP enzyme family
G6536_19960	COG0583	DNA-binding transcription factor activity
G6536_19965	COG0405	Gamma-glutamyltransferase
G6536_19970	COG1522	sequence-specific DNA binding
G6536_19975	COG2059	Chromate
G6536_19980	COG2059	Chromate
G6536_19985	COG4464	protein tyrosine phosphatase activity
G6536_19990	COG3944	biosynthesis protein
G6536_20000	COG4715	Zinc finger, swim domain protein
G6536_20005	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G6536_20010	COG0561	phosphatase activity
G6536_20015	COG1349	DNA-binding transcription factor activity
G6536_20025	COG1028	Short-chain dehydrogenase reductase Sdr
G6536_20035	COG3732	PTS system glucitol sorbitol-specific
G6536_20055	COG0629	single-stranded DNA binding
G6536_20070	COG1970	mechanosensitive ion channel activity
G6536_20075	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G6536_20080	COG4786	Flagellar basal body rod
G6536_20085	COG4786	Flagellar basal body rod
G6536_20090	COG1077	Cell shape determining protein MreB Mrl
G6536_20095	COG1609	Transcriptional regulator
G6536_20105	COG1846	Transcriptional regulator
G6536_20110	COG2814	Major facilitator Superfamily
G6536_20115	COG0671	phosphoesterase, PA-phosphatase related
G6536_20120	COG1227	inorganic diphosphatase activity
G6536_20125	COG3546	catalase activity
G6536_20130	COG3361	conserved protein (COG2071)
G6536_20135	COG0517	IMP dehydrogenase activity
G6536_20140	COG0598	Magnesium transport protein CorA
G6536_20145	COG1253	flavin adenine dinucleotide binding
G6536_20150	COG0004	ammonium transporteR
G6536_20155	COG0347	Belongs to the P(II) protein family
G6536_20160	COG0740	serine-type endopeptidase activity
G6536_20170	COG0739	heme binding
G6536_20175	COG1247	-acetyltransferase
G6536_20185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G6536_20190	COG0477	Major facilitator Superfamily
G6536_20195	COG3251	PFAM MbtH domain protein
G6536_20200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6536_20205	COG1535	isochorismatase
G6536_20205	COG3433	isochorismatase activity
G6536_20210	COG1021	2,3-dihydroxybenzoate-AMP ligase
G6536_20215	COG1169	isochorismate synthase
G6536_20220	COG1028	Short-chain dehydrogenase reductase Sdr
G6536_20225	COG2819	hydrolase of the alpha beta superfamily
G6536_20230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G6536_20235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G6536_20240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G6536_20245	COG2207	Transcriptional regulator
G6536_20245	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G6536_20255	COG2910	NAD(P)H-binding
G6536_20260	COG1959	2 iron, 2 sulfur cluster binding
G6536_20270	COG1994	Peptidase M50
G6536_20275	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G6536_20280	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G6536_20285	COG2223	nitrite transmembrane transporter activity
G6536_20290	COG3383	formate dehydrogenase (NAD+) activity
G6536_20295	COG2304	oxidoreductase activity
G6536_20300	COG2304	oxidoreductase activity
G6536_20305	COG2385	sporulation resulting in formation of a cellular spore
G6536_20310	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G6536_20320	COG4836	Membrane
G6536_20330	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G6536_20335	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G6536_20340	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G6536_20345	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G6536_20350	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G6536_20355	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G6536_20375	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
G6536_20380	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G6536_20385	COG4475	Protein of unknown function (DUF436)
G6536_20390	COG0698	ribose 5-phosphate isomerase
G6536_20395	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G6536_20400	COG1971	Probably functions as a manganese efflux pump
G6536_20405	COG0009	L-threonylcarbamoyladenylate synthase
G6536_20410	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G6536_20420	COG0738	Major facilitator superfamily
G6536_20430	COG0561	phosphatase activity
G6536_20435	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G6536_20440	COG1609	Transcriptional regulator
G6536_20445	COG2890	protein-(glutamine-N5) methyltransferase activity
G6536_20450	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G6536_20455	COG0346	lactoylglutathione lyase activity
G6536_20460	COG0789	Transcriptional regulator
G6536_20465	COG0679	Auxin Efflux Carrier
G6536_20470	COG0281	malic enzyme
G6536_20475	COG1435	thymidine kinase activity
G6536_20480	COG0254	rRNA binding
G6536_20485	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
G6536_20490	COG1494	fructose-1,6-bisphosphatase
G6536_20495	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G6536_20500	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G6536_20505	COG0191	fructose-bisphosphate aldolase activity
G6536_20510	COG2204	response regulator
G6536_20515	COG4821	SIS domain
G6536_20520	COG0504	CTP synthase activity
G6536_20525	COG3343	RNA polymerase activity
G6536_20535	COG1960	acyl-CoA dehydrogenase activity
G6536_20540	COG1960	acyl-CoA dehydrogenase activity
G6536_20545	COG1250	3-hydroxyacyl-CoA dehydrogenase
G6536_20550	COG0183	Belongs to the thiolase family
G6536_20555	COG2181	nitrate reductase activity
G6536_20555	COG0247	lactate metabolic process
G6536_20560	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G6536_20570	COG0018	arginyl-trna synthetase
G6536_20575	COG4506	Protein conserved in bacteria
G6536_20580	COG0010	Belongs to the arginase family
G6536_20585	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
G6536_20610	COG1994	Peptidase M50
G6536_20615	COG1942	4-Oxalocrotonate Tautomerase
G6536_20625	COG3465	dGTPase activity
G6536_20630	COG1078	dGTPase activity
G6536_20635	COG4844	belongs to the
G6536_20660	COG2814	Major facilitator Superfamily
G6536_20685	COG1414	Transcriptional regulator
G6536_20695	COG0280	phosphate acetyltransferase
G6536_20700	COG3253	May function as heme-dependent peroxidase
G6536_20715	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G6536_20735	COG1131	(ABC) transporter
G6536_20750	COG2363	Small membrane protein
G6536_20755	COG2233	PERMEase
G6536_20765	COG1012	belongs to the aldehyde dehydrogenase family
G6536_20770	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G6536_20775	COG1216	Glycosyl transferase, family 2
G6536_20780	COG0351	phosphomethylpyrimidine kinase
G6536_20790	COG1621	beta-fructofuranosidase activity
G6536_20795	COG1263	PTS System
G6536_20795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G6536_20800	COG3711	transcriptional antiterminator
G6536_20810	COG1404	Belongs to the peptidase S8 family
G6536_20820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6536_20825	COG0778	Nitroreductase
G6536_20830	COG1473	amidohydrolase
G6536_20835	COG0772	Belongs to the SEDS family
G6536_20840	COG0772	Belongs to the SEDS family
G6536_20845	COG3314	Sporulation integral membrane protein YlbJ
G6536_20865	COG0456	acetyltransferase
G6536_20900	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
G6536_20910	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G6536_20915	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G6536_20920	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G6536_20940	COG3162	membrane
G6536_20945	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G6536_20950	COG1070	Carbohydrate kinase
G6536_20955	COG2115	Belongs to the xylose isomerase family
G6536_20965	COG0352	thiamine-phosphate diphosphorylase activity
G6536_20970	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
G6536_20975	COG0583	DNA-binding transcription factor activity
G6536_20990	COG1380	Effector of murein hydrolase LrgA
G6536_20995	COG1346	cytolysis
G6536_21005	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G6536_21010	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G6536_21015	COG0346	lactoylglutathione lyase activity
G6536_21020	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G6536_21025	COG1442	glycosyl transferase family 8
G6536_21035	COG4585	Histidine kinase
G6536_21040	COG2197	response regulator
G6536_21050	COG5522	Integral membrane protein (intg_mem_TP0381)
G6536_21055	COG2271	Major facilitator Superfamily
G6536_21060	COG4948	Mandelate Racemase Muconate Lactonizing
G6536_21065	COG0800	Aldolase
G6536_21070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6536_21080	COG2234	aminopeptidase activity
G6536_21085	COG0477	Major facilitator Superfamily
G6536_21095	COG2357	RelA SpoT domain protein
G6536_21110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6536_21115	COG1696	Membrane protein involved in D-alanine export
G6536_21120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G6536_21125	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
G6536_21130	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G6536_21135	COG2814	Major facilitator Superfamily
G6536_21140	COG1486	melibiose metabolic process
G6536_21145	COG1447	Phosphotransferase system cellobiose-specific component IIA
G6536_21150	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G6536_21155	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G6536_21160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G6536_21160	COG3711	transcriptional antiterminator
G6536_21165	COG2094	Belongs to the DNA glycosylase MPG family
G6536_21175	COG0372	Belongs to the citrate synthase family
G6536_21180	COG2079	MmgE PrpD family protein
G6536_21185	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
G6536_21200	COG1132	(ABC) transporter
G6536_21205	COG2755	lipolytic protein G-D-S-L family
G6536_21220	COG2814	Major facilitator Superfamily
G6536_21225	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
G6536_21230	COG1131	(ABC) transporter
G6536_21250	COG1595	DNA-templated transcription, initiation
G6536_21255	COG2814	Major facilitator Superfamily
G6536_21260	COG0753	catalase activity
G6536_21265	COG0753	catalase activity
G6536_21270	COG0735	belongs to the Fur family
G6536_21275	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
G6536_21280	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
G6536_21285	COG1131	(ABC) transporter
G6536_21300	COG1131	(ABC) transporter
G6536_21355	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G6536_21360	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
G6536_21365	COG4988	ABC transporter
G6536_21370	COG1294	oxidase, subunit
G6536_21375	COG1271	oxidase subunit
G6536_21385	COG2116	formate transmembrane transporter activity
G6536_21395	COG0281	malic enzyme
G6536_21400	COG1757	Na H antiporter
G6536_21405	COG1027	Aspartate ammonia-lyase
G6536_21410	COG0252	asparaginase activity
G6536_21415	COG1396	sequence-specific DNA binding
G6536_21420	COG2706	6-phosphogluconolactonase activity
G6536_21425	COG0745	RESPONSE REGULATOR receiver
G6536_21430	COG2205	protein histidine kinase activity
G6536_21440	COG1136	(ABC) transporter
G6536_21445	COG0577	efflux transmembrane transporter activity
G6536_21450	COG5294	Protein conserved in bacteria
G6536_21470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G6536_21475	COG1215	transferase activity, transferring glycosyl groups
G6536_21480	COG3493	citrate carrier protein
G6536_21485	COG0584	glycerophosphoryl diester phosphodiesterase
G6536_21500	COG1368	sulfuric ester hydrolase activity
G6536_21510	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G6536_21525	COG2235	arginine
G6536_21530	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G6536_21540	COG0549	Belongs to the carbamate kinase family
G6536_21550	COG2723	6-phospho-beta-galactosidase activity
G6536_21555	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G6536_21565	COG1595	DNA-templated transcription, initiation
G6536_21575	COG2195	Cleaves the N-terminal amino acid of tripeptides
G6536_21585	COG1621	beta-fructofuranosidase activity
G6536_21590	COG2223	nitrite transmembrane transporter activity
G6536_21595	COG1609	Transcriptional regulator
G6536_21610	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G6536_21615	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G6536_21620	COG0463	Glycosyl transferase, family 2
G6536_21625	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G6536_21635	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G6536_21640	COG0693	protein deglycase activity
G6536_21640	COG0753	catalase activity
G6536_21650	COG2723	6-phospho-beta-galactosidase activity
G6536_21655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G6536_21655	COG2190	(PTS) system
G6536_21655	COG1263	PTS System
G6536_21660	COG3711	transcriptional antiterminator
G6536_21670	COG1122	ATPase activity
G6536_21675	COG4721	ABC-type cobalt transport system, permease component
G6536_21680	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
G6536_21690	COG2224	Isocitrate lyase
G6536_21695	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
G6536_21705	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G6536_21710	COG0577	efflux transmembrane transporter activity
G6536_21715	COG1136	(ABC) transporter
G6536_21720	COG2205	protein histidine kinase activity
G6536_21725	COG0745	RESPONSE REGULATOR receiver
G6536_21730	COG2723	6-phospho-beta-galactosidase activity
G6536_21735	COG2190	(PTS) system
G6536_21735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G6536_21735	COG1263	PTS System
G6536_21745	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
G6536_21760	COG3507	Belongs to the glycosyl hydrolase 43 family
G6536_21765	COG0513	Belongs to the DEAD box helicase family
G6536_21795	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
G6536_21800	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G6536_21805	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
G6536_21810	COG2390	Transcriptional regulator
G6536_21820	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
G6536_21825	COG3706	GGDEF domain
G6536_21830	COG5298	Protein conserved in bacteria
G6536_21845	COG3977	Valine--pyruvate aminotransferase
G6536_21860	COG1181	Belongs to the D-alanine--D-alanine ligase family
G6536_21870	COG0191	fructose-bisphosphate aldolase activity
G6536_21875	COG1082	Xylose isomerase domain protein TIM barrel
G6536_21880	COG1082	Xylose isomerase domain protein TIM barrel
G6536_21885	COG0673	inositol 2-dehydrogenase activity
G6536_21890	COG2814	Major facilitator Superfamily
G6536_21895	COG1082	Xylose isomerase domain protein TIM barrel
G6536_21900	COG3962	Belongs to the TPP enzyme family
G6536_21905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6536_21910	COG3718	enzyme involved in inositol metabolism
G6536_21915	COG1012	belongs to the aldehyde dehydrogenase family
G6536_21920	COG1349	DNA-binding transcription factor activity
G6536_21925	COG0667	Aldo Keto reductase
G6536_21930	COG0584	glycerophosphoryl diester phosphodiesterase
G6536_21935	COG2271	Major facilitator Superfamily
G6536_21940	COG0326	Molecular chaperone. Has ATPase activity
G6536_21945	COG0488	(ABC) transporter
G6536_21950	COG0561	phosphatase activity
G6536_21970	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G6536_22000	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
G6536_22005	COG0577	efflux transmembrane transporter activity
G6536_22010	COG1136	(ABC) transporter
G6536_22015	COG2205	protein histidine kinase activity
G6536_22020	COG0745	RESPONSE REGULATOR receiver
G6536_22030	COG0840	transmembrane signaling receptor activity
G6536_22030	COG5278	phosphoserine phosphatase activity
G6536_22035	COG1115	amino acid carrier protein
G6536_22040	COG0686	Belongs to the AlaDH PNT family
G6536_22045	COG3867	Arabinogalactan endo-beta-1,4-galactanase
G6536_22050	COG1874	Beta-galactosidase
G6536_22055	COG3833	ABC-type maltose transport systems, permease component
G6536_22060	COG1175	transmembrane transport
G6536_22065	COG2182	Extracellular solute-binding protein
G6536_22070	COG1609	Transcriptional regulator
G6536_22080	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G6536_22085	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
G6536_22090	COG1940	carbohydrate kinase activity
G6536_22115	COG1454	alcohol dehydrogenase
G6536_22115	COG1012	belongs to the aldehyde dehydrogenase family
G6536_22120	COG0450	alkyl hydroperoxide reductase
G6536_22125	COG3634	alkyl hydroperoxide reductase activity
G6536_22150	COG1131	(ABC) transporter
G6536_22155	COG0842	Transport permease protein
G6536_22165	COG2197	response regulator
G6536_22195	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
G6536_22210	COG0456	acetyltransferase
G6536_22225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6536_22230	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
G6536_22235	COG4853	Protein conserved in bacteria
G6536_22240	COG4863	YycH protein
G6536_22245	COG5002	protein histidine kinase activity
G6536_22250	COG0745	RESPONSE REGULATOR receiver
G6536_22275	COG1051	belongs to the nudix hydrolase family
G6536_22280	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G6536_22290	COG0305	Participates in initiation and elongation during chromosome replication
G6536_22305	COG3093	addiction module antidote protein HigA
G6536_22310	COG2807	transmembrane transport
G6536_22315	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
G6536_22320	COG0363	glucosamine-6-phosphate deaminase activity
G6536_22325	COG2188	Transcriptional regulator
G6536_22330	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
G6536_22335	COG1263	PTS System
G6536_22335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G6536_22340	COG0359	binds to the 23S rRNA
G6536_22345	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
G6536_22350	COG4241	membrane
G6536_22360	COG5577	PFAM Coat F domain
G6536_22365	COG0589	response to stress
G6536_22370	COG0659	secondary active sulfate transmembrane transporter activity
G6536_22375	COG2271	Major facilitator Superfamily
G6536_22380	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G6536_22385	COG0629	single-stranded DNA binding
G6536_22390	COG0360	Binds together with S18 to 16S ribosomal RNA
G6536_22395	COG0012	GTP binding
G6536_22405	COG4481	Protein conserved in bacteria
G6536_22410	COG3949	Membrane
G6536_22420	COG1475	DNA binding
G6536_22425	COG1192	Involved in chromosome partitioning
G6536_22430	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G6536_22440	COG1475	DNA binding
G6536_22445	COG0357	Ribosomal RNA small subunit methyltransferase G
G6536_22450	COG0445	tRNA wobble uridine modification
G6536_22455	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
G6536_22460	COG1847	R3H domain protein
G6536_22465	COG0706	membrane insertase activity
G6536_22470	COG0594	ribonuclease P activity