locus-tag	class	description
BLi00001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BLi00002	COG0592	DNA-directed DNA polymerase activity
BLi00003	COG2501	S4 domain
BLi00004	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BLi00006	COG0187	DNA topoisomerase II activity
BLi00007	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BLi00014	COG0517	IMP dehydrogenase activity
BLi00014	COG0516	GMP reductase activity
BLi00015	COG1686	Belongs to the peptidase S11 family
BLi00016	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BLi00017	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BLi00018	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BLi00019	COG2610	gluconate transmembrane transporter activity
BLi00020	COG3835	regulator
BLi00023	COG1428	Deoxynucleoside kinase
BLi00024	COG1428	Deoxynucleoside kinase
BLi00025	COG3858	chitin binding
BLi00025	COG1388	LysM domain
BLi00026	COG1335	isochorismatase
BLi00027	COG0590	tRNA wobble adenosine to inosine editing
BLi00028	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BLi00029	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BLi00030	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BLi00038	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
BLi00039	COG3853	Toxic anion resistance protein (TelA)
BLi00040	COG1982	Orn Lys Arg decarboxylase major
BLi00041	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BLi00042	COG3870	Protein conserved in bacteria
BLi00043	COG1728	Protein conserved in bacteria
BLi00044	COG0470	DNA polymerase III
BLi00045	COG1774	PSP1 C-terminal conserved region
BLi00046	COG4467	Involved in initiation control of chromosome replication
BLi00047	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BLi00048	COG2827	Endonuclease containing a URI domain
BLi00049	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BLi00050	COG2002	toxin-antitoxin pair type II binding
BLi00051	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BLi00051	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BLi00052	COG0084	hydrolase, TatD family'
BLi00053	COG3584	3D domain protein
BLi00053	COG3583	domain protein
BLi00054	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BLi00055	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BLi00057	COG4466	Protein conserved in bacteria
BLi00059	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BLi00060	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BLi00061	COG0251	oxidation-reduction process
BLi00062	COG2088	sporulation resulting in formation of a cellular spore
BLi00063	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BLi00064	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BLi00065	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BLi00066	COG0193	aminoacyl-tRNA hydrolase activity
BLi00068	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BLi00069	COG2002	toxin-antitoxin pair type II binding
BLi00070	COG2244	polysaccharide biosynthetic process
BLi00071	COG3956	TIGRFAM MazG family protein
BLi00072	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BLi00075	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BLi00076	COG1098	S1 RNA binding domain
BLi00080	COG2208	phosphoserine phosphatase activity
BLi00081	COG2304	oxidoreductase activity
BLi00082	COG0515	serine threonine protein kinase
BLi00083	COG0037	tRNA processing
BLi00085	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BLi00086	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BLi00087	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BLi00088	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BLi00089	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BLi00090	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BLi00091	COG0512	Glutamine amidotransferase of anthranilate synthase
BLi00092	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BLi00093	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BLi00094	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BLi00095	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BLi00096	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BLi00097	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BLi00101	COG4463	regulation of RNA biosynthetic process
BLi00102	COG3880	PFAM UvrB UvrC protein
BLi00103	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BLi00104	COG0542	response to heat
BLi00105	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BLi00106	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BLi00107	COG4956	integral membrane protein (PIN domain superfamily)
BLi00108	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BLi00109	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BLi00110	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BLi00111	COG1045	serine acetyltransferase
BLi00112	COG0215	cysteine-tRNA ligase activity
BLi00113	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BLi00114	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BLi00115	COG3688	RNA-binding protein containing a PIN domain
BLi00117	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BLi00119	COG0250	Participates in transcription elongation, termination and antitermination
BLi00120	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BLi00121	COG0081	regulation of translation
BLi00122	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BLi00123	COG0222	ribosome binding
BLi00124	COG2813	Specifically methylates the guanine in position
BLi00125	COG0085	RNA polymerase activity
BLi00126	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BLi00127	COG1358	cellular component organization or biogenesis
BLi00128	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BLi00129	COG0049	tRNA binding
BLi00130	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BLi00131	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BLi00132	COG0051	transcription antitermination factor activity, RNA binding
BLi00133	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BLi00134	COG0088	Forms part of the polypeptide exit tunnel
BLi00135	COG0089	rRNA binding
BLi00136	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BLi00137	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BLi00138	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BLi00139	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BLi00140	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BLi00141	COG0255	Belongs to the universal ribosomal protein uL29 family
BLi00142	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BLi00143	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BLi00144	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BLi00145	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BLi00146	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BLi00147	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BLi00148	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BLi00149	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BLi00150	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BLi00151	COG1841	ribosomal large subunit assembly
BLi00152	COG0200	Binds to the 23S rRNA
BLi00153	COG0201	protein transport
BLi00154	COG0563	adenylate kinase activity
BLi00155	COG0024	Methionine aminopeptidase
BLi00156	COG2163	COG2163 Ribosomal protein L14E L6E L27E
BLi00157	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BLi00158	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BLi00159	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BLi00160	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BLi00161	COG0202	RNA polymerase activity
BLi00162	COG0203	ribosomal protein L17
BLi00163	COG1122	ATPase activity
BLi00164	COG1122	ATPase activity
BLi00165	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BLi00166	COG0101	tRNA pseudouridine synthase activity
BLi00167	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BLi00168	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BLi00169	COG2318	DinB family
BLi00171	COG0860	N-Acetylmuramoyl-L-alanine amidase
BLi00172	COG0489	protein tyrosine kinase activity
BLi00174	COG2194	sulfuric ester hydrolase activity
BLi00175	COG0726	polysaccharide deacetylase
BLi00181	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BLi00183	COG0385	Bile acid
BLi00186	COG3876	Protein conserved in bacteria
BLi00187	COG1472	Belongs to the glycosyl hydrolase 3 family
BLi00188	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BLi00189	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLi00189	COG1263	PTS System
BLi00190	COG1737	Transcriptional regulator
BLi00191	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BLi00192	COG1683	Conserved Protein
BLi00199	COG1595	DNA-templated transcription, initiation
BLi00200	COG5662	AntiSigma factor
BLi00201	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BLi00202	COG4856	YbbR-like protein
BLi00203	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BLi00204	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BLi00208	COG1725	Transcriptional regulator
BLi00209	COG0640	Transcriptional regulator
BLi00210	COG2814	Major facilitator Superfamily
BLi00213	COG1132	(ABC) transporter
BLi00214	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BLi00219	COG1011	Hydrolase
BLi00220	COG1113	amino acid transport
BLi00221	COG2851	Citrate transporter
BLi00223	COG3181	Tripartite tricarboxylate transporter family receptor
BLi00224	COG4565	transcriptional regulatory protein
BLi00225	COG3290	protein histidine kinase activity
BLi00227	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BLi00228	COG2211	Major facilitator Superfamily
BLi00234	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BLi00237	COG3220	belongs to the UPF0276 family
BLi00238	COG1253	flavin adenine dinucleotide binding
BLi00239	COG1253	flavin adenine dinucleotide binding
BLi00241	COG0477	Major facilitator Superfamily
BLi00245	COG1283	sodium-dependent phosphate transmembrane transporter activity
BLi00246	COG4682	membrane
BLi00251	COG0697	spore germination
BLi00258	COG0371	Dehydrogenase
BLi00259	COG0840	transmembrane signaling receptor activity
BLi00260	COG4213	ABC transporter substrate-binding protein
BLi00263	COG4257	antibiotic catabolic process
BLi00265	COG0833	amino acid
BLi00266	COG2040	homocysteine
BLi00268	COG1263	PTS System
BLi00268	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLi00268	COG2190	(PTS) system
BLi00269	COG0789	Transcriptional regulator
BLi00270	COG2323	membrane
BLi00273	COG2205	protein histidine kinase activity
BLi00274	COG2066	Belongs to the glutaminase family
BLi00275	COG4191	Histidine kinase
BLi00276	COG0784	Response regulator, receiver
BLi00281	COG3540	Alkaline phosphatase
BLi00282	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BLi00283	COG0805	protein transport
BLi00284	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BLi00285	COG1012	belongs to the aldehyde dehydrogenase family
BLi00286	COG2271	Major facilitator Superfamily
BLi00287	COG4948	Mandelate Racemase Muconate Lactonizing
BLi00288	COG2186	Transcriptional regulator
BLi00289	COG2721	sulfolactate sulfo-lyase activity
BLi00292	COG2205	protein histidine kinase activity
BLi00293	COG1131	(ABC) transporter
BLi00298	COG3173	Aminoglycoside phosphotransferase
BLi00299	COG1846	Transcriptional regulator
BLi00300	COG0318	PFAM AMP-dependent synthetase and ligase
BLi00304	COG0789	Transcriptional regulator
BLi00309	COG0697	spore germination
BLi00310	COG1714	RDD family
BLi00311	COG3012	SEC-C Motif Domain Protein
BLi00311	COG1405	negative regulation of cell septum assembly
BLi00317	COG0583	DNA-binding transcription factor activity
BLi00318	COG1942	4-Oxalocrotonate Tautomerase
BLi00319	COG1028	Short-chain dehydrogenase reductase Sdr
BLi00322	COG1288	antiporter activity
BLi00324	COG0456	acetyltransferase
BLi00326	COG1164	Oligoendopeptidase f
BLi00327	COG2261	transglycosylase associated protein
BLi00329	COG0247	lactate metabolic process
BLi00330	COG0277	FAD linked oxidase domain protein
BLi00332	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BLi00333	COG1447	Phosphotransferase system cellobiose-specific component IIA
BLi00334	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BLi00335	COG1486	melibiose metabolic process
BLi00337	COG3394	polysaccharide catabolic process
BLi00340	COG3591	Belongs to the peptidase S1B family
BLi00341	COG1028	Short-chain dehydrogenase reductase Sdr
BLi00343	COG1595	DNA-templated transcription, initiation
BLi00345	COG3773	Cell wall hydrolase
BLi00346	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BLi00347	COG0791	NLP P60 protein
BLi00347	COG3883	PFAM NLP P60 protein
BLi00349	COG1131	(ABC) transporter
BLi00350	COG1309	transcriptional regulator
BLi00354	COG2310	stress, protein
BLi00355	COG2310	stress, protein
BLi00356	COG2310	stress, protein
BLi00357	COG0861	Integral membrane protein TerC family
BLi00361	COG3853	Toxic anion resistance protein (TelA)
BLi00362	COG0785	Cytochrome C biogenesis protein
BLi00364	COG0789	Transcriptional regulator
BLi00365	COG2223	nitrite transmembrane transporter activity
BLi00366	COG0039	L-malate dehydrogenase activity
BLi00367	COG1620	l-lactate permease
BLi00368	COG1280	lysine exporter protein (LysE YggA)
BLi00369	COG1113	amino acid transport
BLi00370	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BLi00371	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BLi00372	COG3541	Predicted nucleotidyltransferase
BLi00373	COG0506	proline dehydrogenase activity
BLi00374	COG1012	belongs to the aldehyde dehydrogenase family
BLi00375	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BLi00376	COG2508	Transcriptional regulator
BLi00377	COG3689	TIGRFAM TIGR03943 family protein
BLi00378	COG0701	Predicted permease
BLi00379	COG3458	cephalosporin-C deacetylase activity
BLi00383	COG0765	amino acid transport
BLi00384	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BLi00385	COG2249	NAD(P)H dehydrogenase (quinone) activity
BLi00387	COG2723	6-phospho-beta-galactosidase activity
BLi00389	COG3209	COG3209 Rhs family protein
BLi00391	COG0515	serine threonine protein kinase
BLi00391	COG3266	domain, Protein
BLi00394	COG5444	nuclease activity
BLi00399	COG1176	ABC-type spermidine putrescine transport system, permease component I
BLi00400	COG1177	transmembrane transport
BLi00401	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BLi00402	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BLi00403	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BLi00404	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BLi00405	COG0697	spore germination
BLi00406	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BLi00408	COG2819	hydrolase of the alpha beta superfamily
BLi00409	COG2207	Transcriptional regulator
BLi00409	COG3708	Transcriptional regulator
BLi00410	COG2364	Membrane
BLi00412	COG1131	(ABC) transporter
BLi00418	COG1126	abc transporter atp-binding protein
BLi00419	COG0765	amino acid transport
BLi00420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BLi00421	COG3829	transcription factor binding
BLi00422	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BLi00423	COG0833	amino acid
BLi00424	COG0010	Belongs to the arginase family
BLi00425	COG0583	DNA-binding transcription factor activity
BLi00426	COG0163	prenyltransferase activity
BLi00427	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BLi00436	COG5444	nuclease activity
BLi00440	COG2972	Histidine kinase
BLi00441	COG4753	response regulator
BLi00441	COG2207	Transcriptional regulator
BLi00442	COG4213	ABC transporter substrate-binding protein
BLi00444	COG4214	carbohydrate transport
BLi00445	COG2271	Major facilitator Superfamily
BLi00446	COG1846	Transcriptional regulator
BLi00446	COG0456	acetyltransferase
BLi00447	COG1874	Beta-galactosidase
BLi00448	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
BLi00449	COG3104	oligopeptide transport
BLi00451	COG5434	Belongs to the glycosyl hydrolase 28 family
BLi00453	COG0697	spore germination
BLi00455	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BLi00456	COG0789	Transcriptional regulator
BLi00457	COG1136	(ABC) transporter
BLi00458	COG0577	efflux transmembrane transporter activity
BLi00459	COG0745	RESPONSE REGULATOR receiver
BLi00460	COG5002	protein histidine kinase activity
BLi00460	COG3850	Histidine kinase
BLi00461	COG0840	transmembrane signaling receptor activity
BLi00462	COG0527	aspartate kinase activity
BLi00463	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLi00464	COG4605	iron ion homeostasis
BLi00465	COG4604	ABC transporter, ATP-binding protein
BLi00466	COG4607	ABC-type enterochelin transport system periplasmic component
BLi00467	COG2814	Major facilitator Superfamily
BLi00468	COG1309	transcriptional regulator
BLi00470	COG0778	Nitroreductase
BLi00471	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BLi00472	COG0640	Transcriptional regulator
BLi00473	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BLi00474	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BLi00475	COG0531	amino acid
BLi00476	COG1012	belongs to the aldehyde dehydrogenase family
BLi00477	COG0697	spore germination
BLi00479	COG4549	nuclear export factor GLE1
BLi00480	COG1276	copper resistance
BLi00480	COG2372	response to copper ion
BLi00481	COG1349	DNA-binding transcription factor activity
BLi00482	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BLi00483	COG0243	molybdopterin cofactor binding
BLi00484	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BLi00485	COG2146	nitrite reductase [NAD(P)H] activity
BLi00486	COG1587	Uroporphyrinogen-III synthase
BLi00486	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BLi00487	COG1802	Transcriptional regulator
BLi00488	COG0471	metal ion transport
BLi00489	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BLi00490	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BLi00492	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLi00495	COG3959	Transketolase, thiamine diphosphate binding domain
BLi00496	COG3958	Transketolase
BLi00497	COG0561	phosphatase activity
BLi00498	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BLi00499	COG1914	H( )-stimulated, divalent metal cation uptake system
BLi00500	COG4336	lyase activity
BLi00501	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BLi00502	COG1984	allophanate hydrolase subunit 2
BLi00503	COG1414	Transcriptional regulator
BLi00504	COG2755	lipolytic protein G-D-S-L family
BLi00505	COG2213	PTS system mannitol-specific
BLi00506	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLi00507	COG0246	Mannitol dehydrogenase
BLi00508	COG3711	transcriptional antiterminator
BLi00509	COG1028	Short-chain dehydrogenase reductase Sdr
BLi00510	COG1917	Cupin 2, conserved barrel domain protein
BLi00512	COG3871	stress protein (general stress protein 26)
BLi00514	COG1316	TRANSCRIPTIONal
BLi00515	COG2814	Major facilitator Superfamily
BLi00517	COG1522	sequence-specific DNA binding
BLi00518	COG0551	DNA topoisomerase type I activity
BLi00518	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BLi00519	COG0531	amino acid
BLi00520	COG0028	Belongs to the TPP enzyme family
BLi00521	COG3397	chitin binding
BLi00522	COG2801	Transposase and inactivated derivatives
BLi00525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BLi00526	COG1914	H( )-stimulated, divalent metal cation uptake system
BLi00527	COG2261	transglycosylase associated protein
BLi00528	COG1027	Aspartate ammonia-lyase
BLi00529	COG1819	glycosyl
BLi00530	COG4876	unkown
BLi00531	COG2217	Heavy metal translocating P-type atpase
BLi00533	COG0662	Cupin 2, conserved barrel domain protein
BLi00534	COG3729	General stress protein
BLi00535	COG0628	permease
BLi00536	COG1301	dicarboxylic acid transport
BLi00537	COG1131	(ABC) transporter
BLi00538	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BLi00540	COG1960	acyl-CoA dehydrogenase activity
BLi00542	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLi00543	COG1181	Belongs to the D-alanine--D-alanine ligase family
BLi00544	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BLi00546	COG0513	Belongs to the DEAD box helicase family
BLi00547	COG3402	PFAM membrane-flanked domain
BLi00548	COG3428	Bacterial PH domain
BLi00549	COG0705	Rhomboid family
BLi00550	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BLi00551	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BLi00552	COG0864	Transcriptional regulator
BLi00553	COG2337	Toxic component of a toxin-antitoxin (TA) module
BLi00554	COG1366	Belongs to the anti-sigma-factor antagonist family
BLi00555	COG1366	Belongs to the anti-sigma-factor antagonist family
BLi00556	COG2172	sigma factor antagonist activity
BLi00557	COG2208	phosphoserine phosphatase activity
BLi00559	COG2172	sigma factor antagonist activity
BLi00560	COG1191	sigma factor activity
BLi00561	COG2208	phosphoserine phosphatase activity
BLi00562	COG2183	response to ionizing radiation
BLi00563	COG1309	transcriptional regulator
BLi00564	COG2409	Drug exporters of the RND superfamily
BLi00564	COG1033	growth of symbiont in host cell
BLi00565	COG3091	SprT-like family
BLi00573	COG0697	spore germination
BLi00575	COG1476	TRANSCRIPTIONal
BLi00576	COG3239	Fatty acid desaturase
BLi00578	COG1278	Cold shock
BLi00579	COG1063	alcohol dehydrogenase
BLi00580	COG2364	Membrane
BLi00581	COG1846	Transcriptional regulator
BLi00582	COG0456	acetyltransferase
BLi00583	COG2808	Putative FMN-binding domain
BLi00585	COG1733	regulation of RNA biosynthetic process
BLi00586	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BLi00588	COG0583	DNA-binding transcription factor activity
BLi00591	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BLi00592	COG1113	amino acid transport
BLi00595	COG1595	DNA-templated transcription, initiation
BLi00597	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BLi00597	COG2755	lipolytic protein G-D-S-L family
BLi00598	COG2814	Major facilitator Superfamily
BLi00599	COG0745	RESPONSE REGULATOR receiver
BLi00599	COG2972	Histidine kinase
BLi00600	COG3279	Response regulator of the LytR AlgR family
BLi00602	COG3764	Sortase (surface protein transpeptidase)
BLi00603	COG2814	Major facilitator Superfamily
BLi00611	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BLi00612	COG0802	atpase or kinase
BLi00613	COG1214	PFAM Peptidase M22, glycoprotease
BLi00614	COG0456	acetyltransferase
BLi00615	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BLi00616	COG0488	(ABC) transporter
BLi00617	COG0315	cyclic pyranopterin monophosphate synthase activity
BLi00618	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BLi00619	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BLi00620	COG0805	protein transport
BLi00622	COG1266	CAAX protease self-immunity
BLi00623	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BLi00624	COG0459	protein refolding
BLi00628	COG2720	vancomycin resistance protein
BLi00631	COG2135	peptidase activity
BLi00633	COG1309	transcriptional regulator
BLi00634	COG3848	Pyruvate phosphate dikinase
BLi00634	COG0574	Belongs to the PEP-utilizing enzyme family
BLi00636	COG3189	MarR family transcriptional regulator
BLi00637	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BLi00638	COG2272	Belongs to the type-B carboxylesterase lipase family
BLi00639	COG2814	Major facilitator Superfamily
BLi00640	COG1842	Phage shock protein A
BLi00641	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BLi00642	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BLi00643	COG4260	virion core protein, lumpy skin disease virus
BLi00645	COG1378	Sugar-specific transcriptional regulator TrmB
BLi00646	COG1280	lysine exporter protein (LysE YggA)
BLi00647	COG3339	Conserved Protein
BLi00648	COG0772	Belongs to the SEDS family
BLi00649	COG0772	Belongs to the SEDS family
BLi00655	COG0726	polysaccharide deacetylase
BLi00657	COG1609	Transcriptional regulator
BLi00658	COG0366	Alpha amylase catalytic
BLi00659	COG2182	Extracellular solute-binding protein
BLi00660	COG1175	transmembrane transport
BLi00661	COG3833	ABC-type maltose transport systems, permease component
BLi00662	COG5521	maltodextrose utilization protein MalA
BLi00663	COG1554	hydrolase, family 65, central catalytic
BLi00664	COG0366	Alpha amylase catalytic
BLi00665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BLi00666	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BLi00667	COG1846	Transcriptional regulator
BLi00670	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BLi00671	COG0823	Involved in the tonB-independent uptake of proteins
BLi00677	COG0702	epimerase
BLi00679	COG2132	Multicopper oxidase
BLi00682	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BLi00683	COG0714	Associated with various cellular activities
BLi00684	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BLi00685	COG1305	Transglutaminase-like
BLi00686	COG0519	Catalyzes the synthesis of GMP from XMP
BLi00686	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BLi00688	COG2252	PERMEase
BLi00691	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BLi00693	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BLi00694	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BLi00695	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BLi00696	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BLi00697	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BLi00698	COG0047	phosphoribosylformylglycinamidine synthase activity
BLi00699	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BLi00700	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BLi00701	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BLi00702	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BLi00703	COG0138	bifunctional purine biosynthesis protein purh
BLi00704	COG0151	Belongs to the GarS family
BLi00706	COG2124	cytochrome p450
BLi00711	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BLi00712	COG1470	cell adhesion involved in biofilm formation
BLi00713	COG4496	protein, YerC YecD
BLi00714	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BLi00715	COG0210	DNA helicase
BLi00716	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BLi00717	COG4851	CamS sex pheromone cAM373 precursor
BLi00718	COG2188	Transcriptional regulator
BLi00722	COG1735	metal-dependent hydrolase with the TIM-barrel fold
BLi00723	COG0626	cystathionine gamma-synthase activity
BLi00724	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BLi00725	COG3457	Alanine racemase
BLi00726	COG0363	glucosamine-6-phosphate deaminase activity
BLi00727	COG1285	pathogenesis
BLi00728	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BLi00730	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BLi00731	COG0154	amidase activity
BLi00732	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BLi00735	COG4124	Belongs to the glycosyl hydrolase 26 family
BLi00736	COG1309	transcriptional regulator
BLi00737	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BLi00739	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BLi00740	COG1957	nucleoside hydrolase
BLi00741	COG1597	lipid kinase activity
BLi00742	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BLi00746	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BLi00748	COG2190	(PTS) system
BLi00748	COG1263	PTS System
BLi00748	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLi00749	COG2723	6-phospho-beta-galactosidase activity
BLi00750	COG3711	transcriptional antiterminator
BLi00751	COG0457	Tetratricopeptide repeat
BLi00754	COG0217	transcriptional regulatory protein
BLi00757	COG1012	belongs to the aldehyde dehydrogenase family
BLi00758	COG0840	transmembrane signaling receptor activity
BLi00759	COG0471	metal ion transport
BLi00760	COG0488	(ABC) transporter
BLi00762	COG1469	GTP cyclohydrolase I activity
BLi00765	COG0523	cobalamin synthesis protein
BLi00766	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
BLi00767	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BLi00768	COG0156	8-amino-7-oxononanoate synthase activity
BLi00769	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BLi00770	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BLi00771	COG2124	cytochrome p450
BLi00773	COG0789	Transcriptional regulator
BLi00774	COG2814	Major facilitator Superfamily
BLi00775	COG0488	(ABC) transporter
BLi00776	COG0513	Belongs to the DEAD box helicase family
BLi00777	COG2130	NADP-dependent
BLi00780	COG0471	metal ion transport
BLi00783	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BLi00785	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BLi00786	COG5658	integral membrane protein
BLi00787	COG0640	Transcriptional regulator
BLi00788	COG1254	Belongs to the acylphosphatase family
BLi00789	COG2258	MOSC domain
BLi00792	COG0024	Methionine aminopeptidase
BLi00793	COG1368	sulfuric ester hydrolase activity
BLi00795	COG1115	amino acid carrier protein
BLi00796	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLi00796	COG1263	PTS System
BLi00797	COG0366	Alpha amylase catalytic
BLi00798	COG2188	Transcriptional regulator
BLi00802	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BLi00803	COG1045	serine acetyltransferase
BLi00804	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BLi00806	COG1215	transferase activity, transferring glycosyl groups
BLi00807	COG0463	Glycosyl transferase, family 2
BLi00807	COG0457	Tetratricopeptide repeat
BLi00809	COG0673	inositol 2-dehydrogenase activity
BLi00812	COG1733	regulation of RNA biosynthetic process
BLi00813	COG0778	Nitroreductase
BLi00814	COG0737	Belongs to the 5'-nucleotidase family
BLi00815	COG0693	protein deglycase activity
BLi00816	COG4840	Belongs to the UPF0435 family
BLi00817	COG1115	amino acid carrier protein
BLi00818	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BLi00819	COG4980	gas vesicle protein
BLi00820	COG1295	ribonuclease BN
BLi00821	COG0477	Major facilitator Superfamily
BLi00823	COG0387	Pfam Sodium calcium exchanger
BLi00825	COG0535	radical SAM domain protein
BLi00827	COG0726	polysaccharide deacetylase
BLi00828	COG0371	Dehydrogenase
BLi00830	COG0598	Magnesium transport protein CorA
BLi00831	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BLi00832	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BLi00833	COG4637	Psort location Cytoplasmic, score
BLi00839	COG1819	glycosyl
BLi00841	COG0477	Major facilitator Superfamily
BLi00842	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLi00842	COG1263	PTS System
BLi00843	COG3711	transcriptional antiterminator
BLi00844	COG0288	reversible hydration of carbon dioxide
BLi00845	COG3002	Belongs to the UPF0753 family
BLi00846	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BLi00847	COG5609	conserved protein (DUF2294)
BLi00849	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BLi00850	COG0022	dehydrogenase e1 component
BLi00851	COG0508	dehydrogenase complex catalyzes the overall conversion of
BLi00852	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BLi00853	COG3284	Transcriptional regulator
BLi00854	COG1742	UPF0060 membrane protein
BLi00855	COG1486	melibiose metabolic process
BLi00856	COG1737	Transcriptional regulator
BLi00857	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLi00857	COG1263	PTS System
BLi00860	COG1733	regulation of RNA biosynthetic process
BLi00861	COG2259	Doxx family
BLi00862	COG2514	catechol 2,3-dioxygenase activity
BLi00864	COG3507	Belongs to the glycosyl hydrolase 43 family
BLi00865	COG1917	Cupin 2, conserved barrel domain protein
BLi00865	COG2207	Transcriptional regulator
BLi00866	COG1653	transport
BLi00867	COG2249	NAD(P)H dehydrogenase (quinone) activity
BLi00868	COG1051	belongs to the nudix hydrolase family
BLi00871	COG0392	lysyltransferase activity
BLi00871	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BLi00872	COG0384	phenazine biosynthesis protein PhzF
BLi00873	COG0778	Nitroreductase
BLi00876	COG1090	epimerase
BLi00877	COG2137	regulation of response to DNA damage stimulus
BLi00881	COG0463	Glycosyl transferase, family 2
BLi00883	COG4485	Bacterial membrane protein, YfhO
BLi00884	COG1988	membrane-bound metal-dependent
BLi00885	COG1194	a g-specific adenine glycosylase
BLi00887	COG1028	Short-chain dehydrogenase reductase Sdr
BLi00890	COG3557	Belongs to the UPF0374 family
BLi00891	COG1132	(ABC) transporter
BLi00892	COG0444	Belongs to the ABC transporter superfamily
BLi00893	COG4608	Belongs to the ABC transporter superfamily
BLi00894	COG0747	negative chemotaxis
BLi00897	COG4129	membrane
BLi00898	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BLi00899	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BLi00900	COG0735	belongs to the Fur family
BLi00922	COG0457	Tetratricopeptide repeat
BLi00933	COG5444	nuclease activity
BLi00935	COG5444	nuclease activity
BLi00936	COG0457	Tetratricopeptide repeat
BLi00937	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BLi00939	COG0710	3-dehydroquinate dehydratase activity
BLi00940	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BLi00941	COG1116	anion transmembrane transporter activity
BLi00942	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BLi00943	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BLi00944	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BLi00946	COG1476	TRANSCRIPTIONal
BLi00948	COG1131	(ABC) transporter
BLi00952	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BLi00954	COG3382	B3 4 domain protein
BLi00955	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BLi00957	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BLi00958	COG0789	Transcriptional regulator
BLi00959	COG1664	Polymer-forming cytoskeletal
BLi00962	COG2766	serine protein kinase
BLi00963	COG2718	Belongs to the UPF0229 family
BLi00964	COG1566	PFAM secretion protein HlyD family protein
BLi00965	COG2814	Major facilitator Superfamily
BLi00966	COG0655	NAD(P)H dehydrogenase (quinone) activity
BLi00969	COG1131	(ABC) transporter
BLi00970	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BLi00971	COG1278	Cold shock
BLi00972	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BLi00973	COG2011	ABC-type metal ion transport system permease component
BLi00974	COG1464	Belongs to the NlpA lipoprotein family
BLi00975	COG1823	symporter activity
BLi00980	COG5577	PFAM Coat F domain
BLi00981	COG5002	protein histidine kinase activity
BLi00982	COG1525	nuclease
BLi00982	COG0737	Belongs to the 5'-nucleotidase family
BLi00982	COG4085	toxin activity
BLi00983	COG3764	Sortase (surface protein transpeptidase)
BLi00984	COG0564	pseudouridine synthase activity
BLi00986	COG0517	IMP dehydrogenase activity
BLi00987	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BLi00988	COG3153	acetyltransferase
BLi00988	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BLi00989	COG0488	(ABC) transporter
BLi00990	COG2116	formate transmembrane transporter activity
BLi00991	COG0679	Auxin Efflux Carrier
BLi00992	COG0604	alcohol dehydrogenase
BLi00993	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BLi00994	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BLi00995	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BLi00996	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BLi00997	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BLi01000	COG4585	Histidine kinase
BLi01000	COG2203	Gaf domain
BLi01001	COG2197	response regulator
BLi01002	COG0431	NADPH-dependent FMN reductase
BLi01005	COG1959	2 iron, 2 sulfur cluster binding
BLi01006	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BLi01006	COG1017	nitric oxide dioxygenase activity
BLi01007	COG2719	SpoVR family
BLi01008	COG0791	NLP P60 protein
BLi01008	COG1388	LysM domain
BLi01009	COG0583	DNA-binding transcription factor activity
BLi01010	COG0372	Belongs to the citrate synthase family
BLi01011	COG2133	pyrroloquinoline quinone binding
BLi01012	COG1028	Short-chain dehydrogenase reductase Sdr
BLi01013	COG0733	neurotransmitter:sodium symporter activity
BLi01015	COG3708	Transcriptional regulator
BLi01015	COG2207	Transcriptional regulator
BLi01016	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BLi01020	COG1595	DNA-templated transcription, initiation
BLi01021	COG0662	Cupin 2, conserved barrel domain protein
BLi01022	COG0204	Acyl-transferase
BLi01023	COG3152	Membrane
BLi01025	COG1309	transcriptional regulator
BLi01026	COG1253	flavin adenine dinucleotide binding
BLi01027	COG0789	Transcriptional regulator
BLi01028	COG1253	flavin adenine dinucleotide binding
BLi01032	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BLi01033	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BLi01034	COG0584	glycerophosphoryl diester phosphodiesterase
BLi01036	COG0668	transmembrane transport
BLi01037	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BLi01039	COG0726	polysaccharide deacetylase
BLi01041	COG1757	Na H antiporter
BLi01042	COG2017	converts alpha-aldose to the beta-anomer
BLi01046	COG0589	response to stress
BLi01047	COG1132	(ABC) transporter
BLi01048	COG1132	(ABC) transporter
BLi01049	COG0702	epimerase
BLi01052	COG3842	ATPase activity
BLi01053	COG2508	Transcriptional regulator
BLi01055	COG0189	ligase activity
BLi01056	COG0189	ligase activity
BLi01057	COG4399	Belongs to the UPF0754 family
BLi01058	COG3679	Belongs to the UPF0342 family
BLi01060	COG0561	phosphatase activity
BLi01061	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BLi01062	COG1024	Enoyl-CoA hydratase
BLi01063	COG0457	Tetratricopeptide repeat
BLi01066	COG4152	abc transporter atp-binding protein
BLi01067	COG1668	transmembrane transport
BLi01068	COG0420	3'-5' exonuclease activity
BLi01069	COG4717	serine-type aminopeptidase activity
BLi01070	COG3481	metal-dependent phosphohydrolase, HD sub domain
BLi01072	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BLi01078	COG1846	Transcriptional regulator
BLi01079	COG4980	gas vesicle protein
BLi01082	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BLi01083	COG0537	adenosine 5'-monophosphoramidase activity
BLi01085	COG1131	(ABC) transporter
BLi01086	COG4473	ABC transporter
BLi01088	COG1473	amidohydrolase
BLi01089	COG3069	C4-dicarboxylate transmembrane transporter activity
BLi01090	COG2329	Antibiotic biosynthesis monooxygenase
BLi01091	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BLi01092	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BLi01095	COG1309	transcriptional regulator
BLi01096	COG1511	domain protein
BLi01097	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BLi01098	COG1363	Peptidase, m42
BLi01100	COG1301	dicarboxylic acid transport
BLi01101	COG1234	tRNA 3'-trailer cleavage
BLi01102	COG0095	Lipoate-protein ligase
BLi01103	COG0318	PFAM AMP-dependent synthetase and ligase
BLi01105	COG1396	sequence-specific DNA binding
BLi01108	COG0501	Belongs to the peptidase M48B family
BLi01110	COG0697	spore germination
BLi01111	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BLi01112	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLi01113	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLi01114	COG0406	alpha-ribazole phosphatase activity
BLi01115	COG0840	transmembrane signaling receptor activity
BLi01116	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BLi01116	COG0723	plastoquinol--plastocyanin reductase activity
BLi01117	COG1028	Short-chain dehydrogenase reductase Sdr
BLi01119	COG4903	ComK protein
BLi01121	COG0398	Pfam SNARE associated Golgi protein
BLi01122	COG0681	Belongs to the peptidase S26 family
BLi01123	COG1404	Belongs to the peptidase S8 family
BLi01125	COG2508	Transcriptional regulator
BLi01126	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BLi01127	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BLi01128	COG3257	ureidoglycine aminohydrolase activity
BLi01129	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BLi01130	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BLi01131	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BLi01132	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BLi01134	COG0549	Belongs to the carbamate kinase family
BLi01135	COG2814	Major facilitator Superfamily
BLi01137	COG0457	Tetratricopeptide repeat
BLi01143	COG1486	melibiose metabolic process
BLi01144	COG3180	Ammonia monooxygenase
BLi01147	COG3546	catalase activity
BLi01148	COG0318	PFAM AMP-dependent synthetase and ligase
BLi01149	COG0477	Major facilitator Superfamily
BLi01149	COG2814	Major facilitator Superfamily
BLi01151	COG5002	protein histidine kinase activity
BLi01152	COG0745	RESPONSE REGULATOR receiver
BLi01153	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BLi01154	COG0725	ABC transporter, periplasmic molybdate-binding protein
BLi01155	COG4149	molybdate abc transporter
BLi01156	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BLi01157	COG1074	ATP-dependent DNA helicase activity
BLi01158	COG0420	3'-5' exonuclease activity
BLi01159	COG0419	ATPase involved in DNA repair
BLi01168	COG5337	Spore coat protein CotH
BLi01170	COG0179	Fumarylacetoacetate (FAA) hydrolase
BLi01174	COG0367	asparagine synthase
BLi01175	COG0004	ammonium transporteR
BLi01176	COG0347	Belongs to the P(II) protein family
BLi01177	COG0534	Mate efflux family protein
BLi01178	COG2207	Transcriptional regulator
BLi01178	COG1917	Cupin 2, conserved barrel domain protein
BLi01180	COG1609	Transcriptional regulator
BLi01181	COG0673	inositol 2-dehydrogenase activity
BLi01182	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BLi01184	COG0076	glutamate decarboxylase activity
BLi01189	COG2153	protein acetylation
BLi01190	COG1028	Short-chain dehydrogenase reductase Sdr
BLi01191	COG2378	regulation of single-species biofilm formation
BLi01192	COG0646	methionine synthase
BLi01192	COG1410	methionine synthase
BLi01193	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BLi01193	COG0646	methionine synthase
BLi01194	COG1666	GTP binding
BLi01195	COG2996	Protein conserved in bacteria
BLi01197	COG1307	EDD domain protein, DegV family
BLi01198	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BLi01200	COG0516	GMP reductase activity
BLi01203	COG0561	phosphatase activity
BLi01204	COG1073	alpha beta
BLi01205	COG2151	metal-sulfur cluster biosynthetic enzyme
BLi01206	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BLi01207	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BLi01208	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BLi01209	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BLi01210	COG0505	Belongs to the CarA family
BLi01211	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BLi01212	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BLi01213	COG1968	undecaprenyl-diphosphatase activity
BLi01216	COG2267	carboxylic ester hydrolase activity
BLi01218	COG1744	ABC transporter substrate-binding protein PnrA-like
BLi01221	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BLi01222	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BLi01223	COG5504	Zn-dependent protease
BLi01224	COG0444	Belongs to the ABC transporter superfamily
BLi01225	COG4608	Belongs to the ABC transporter superfamily
BLi01227	COG0601	transmembrane transport
BLi01228	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BLi01231	COG0180	Tryptophanyl-tRNA synthetase
BLi01232	COG4166	transmembrane transport
BLi01233	COG0601	transmembrane transport
BLi01234	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BLi01235	COG0444	Belongs to the ABC transporter superfamily
BLi01236	COG4608	Belongs to the ABC transporter superfamily
BLi01237	COG0456	acetyltransferase
BLi01238	COG1393	Belongs to the ArsC family
BLi01240	COG4862	establishment of competence for transformation
BLi01244	COG4565	transcriptional regulatory protein
BLi01245	COG3290	protein histidine kinase activity
BLi01246	COG4469	Competence protein
BLi01247	COG1164	Oligoendopeptidase f
BLi01250	COG2346	COG2346, Truncated hemoglobins
BLi01251	COG0741	lytic transglycosylase activity
BLi01252	COG4116	CYTH
BLi01254	COG2357	RelA SpoT domain protein
BLi01255	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BLi01256	COG0564	pseudouridine synthase activity
BLi01257	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BLi01258	COG0569	domain protein
BLi01258	COG0475	glutathione-regulated potassium exporter activity
BLi01259	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BLi01260	COG0352	thiamine-phosphate diphosphorylase activity
BLi01262	COG2104	thiamine diphosphate biosynthetic process
BLi01263	COG2022	thiamine diphosphate biosynthetic process
BLi01264	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BLi01265	COG0351	phosphomethylpyrimidine kinase
BLi01266	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BLi01277	COG0210	DNA helicase
BLi01279	COG0586	Pfam SNARE associated Golgi protein
BLi01280	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BLi01281	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BLi01282	COG2246	polysaccharide biosynthetic process
BLi01283	COG2153	protein acetylation
BLi01284	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BLi01285	COG2382	esterase
BLi01289	COG0626	cystathionine gamma-synthase activity
BLi01290	COG0626	cystathionine gamma-synthase activity
BLi01291	COG5505	Protein of unknown function (DUF819)
BLi01294	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BLi01295	COG3507	Belongs to the glycosyl hydrolase 43 family
BLi01298	COG0110	maltose O-acetyltransferase activity
BLi01300	COG0583	DNA-binding transcription factor activity
BLi01302	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BLi01303	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BLi01306	COG0697	spore germination
BLi01307	COG0346	lactoylglutathione lyase activity
BLi01309	COG3584	3D domain protein
BLi01309	COG1388	LysM domain
BLi01310	COG2814	Major facilitator Superfamily
BLi01311	COG1309	transcriptional regulator
BLi01315	COG5444	nuclease activity
BLi01316	COG4195	phage-related replication protein
BLi01317	COG2856	Zn peptidase
BLi01318	COG1396	sequence-specific DNA binding
BLi01321	COG1522	sequence-specific DNA binding
BLi01322	COG1484	DNA-dependent DNA replication
BLi01326	COG1595	DNA-templated transcription, initiation
BLi01327	COG3728	DNA packaging
BLi01327	COG5484	DNA packaging
BLi01328	COG1783	phage Terminase large subunit
BLi01329	COG5518	Phage portal protein
BLi01330	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BLi01331	COG4653	Phage capsid family
BLi01341	COG5412	phage tail tape measure protein
BLi01341	COG3953	SLT domain
BLi01342	COG1652	LysM domain
BLi01343	COG4193	domain, Protein
BLi01345	COG3628	GPW Gp25 family protein
BLi01346	COG3299	homolog of phage Mu protein gp47
BLi01347	COG3778	Protein conserved in bacteria
BLi01354	COG1802	Transcriptional regulator
BLi01355	COG1063	alcohol dehydrogenase
BLi01356	COG1312	Catalyzes the dehydration of D-mannonate
BLi01357	COG1028	Short-chain dehydrogenase reductase Sdr
BLi01358	COG1063	alcohol dehydrogenase
BLi01359	COG2271	Major facilitator Superfamily
BLi01362	COG0306	phosphate transporter
BLi01363	COG1392	Phosphate transport regulator
BLi01364	COG0405	Gamma-glutamyltransferase
BLi01365	COG5578	integral membrane protein
BLi01366	COG2972	Histidine kinase
BLi01367	COG4753	response regulator
BLi01367	COG2207	Transcriptional regulator
BLi01368	COG1653	transport
BLi01369	COG1175	transmembrane transport
BLi01370	COG0395	ABC-type sugar transport system, permease component
BLi01371	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BLi01372	COG2207	Transcriptional regulator
BLi01373	COG2755	lipolytic protein G-D-S-L family
BLi01375	COG5578	integral membrane protein
BLi01376	COG3401	FG-GAP repeat protein
BLi01378	COG2755	lipolytic protein G-D-S-L family
BLi01379	COG3401	FG-GAP repeat protein
BLi01380	COG0667	Aldo Keto reductase
BLi01381	COG2755	lipolytic protein G-D-S-L family
BLi01382	COG1874	Beta-galactosidase
BLi01384	COG1653	transport
BLi01385	COG4209	transmembrane transport
BLi01386	COG0395	ABC-type sugar transport system, permease component
BLi01387	COG0531	amino acid
BLi01388	COG0346	lactoylglutathione lyase activity
BLi01390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BLi01391	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BLi01392	COG2362	D-Aminopeptidase
BLi01393	COG0601	transmembrane transport
BLi01394	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BLi01395	COG0444	Belongs to the ABC transporter superfamily
BLi01396	COG4166	transmembrane transport
BLi01397	COG1619	proteins homologs of microcin C7 resistance protein MccF
BLi01398	COG4948	Mandelate Racemase Muconate Lactonizing
BLi01399	COG0791	NLP P60 protein
BLi01400	COG4608	Belongs to the ABC transporter superfamily
BLi01401	COG1834	amidinotransferase
BLi01402	COG1607	acyl-coa hydrolase
BLi01403	COG2323	membrane
BLi01404	COG3866	Pectate lyase
BLi01408	COG2318	DinB family
BLi01409	COG2076	Multidrug Resistance protein
BLi01410	COG2076	Multidrug Resistance protein
BLi01411	COG0788	formyltetrahydrofolate deformylase activity
BLi01412	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BLi01413	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BLi01414	COG1764	response to oxidative stress
BLi01415	COG1846	Transcriptional regulator
BLi01416	COG1764	response to oxidative stress
BLi01418	COG0590	tRNA wobble adenosine to inosine editing
BLi01419	COG0406	alpha-ribazole phosphatase activity
BLi01422	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BLi01423	COG1404	Belongs to the peptidase S8 family
BLi01426	COG2239	Acts as a magnesium transporter
BLi01428	COG0582	viral genome integration into host DNA
BLi01429	COG2856	Zn peptidase
BLi01433	COG3620	sequence-specific DNA binding
BLi01440	COG5377	YqaJ viral recombinase family
BLi01441	COG3723	Recombinational DNA repair protein, rece pathway
BLi01442	COG3935	DnaD domain protein
BLi01443	COG1484	DNA-dependent DNA replication
BLi01452	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
BLi01453	COG0629	single-stranded DNA binding
BLi01460	COG3677	Transposase
BLi01463	COG5484	DNA packaging
BLi01464	COG1783	phage Terminase large subunit
BLi01487	COG0662	Cupin 2, conserved barrel domain protein
BLi01488	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BLi01489	COG2323	membrane
BLi01490	COG0789	Transcriptional regulator
BLi01493	COG1846	Transcriptional regulator
BLi01494	COG3285	dna ligase
BLi01494	COG1793	dna ligase
BLi01495	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BLi01496	COG3300	MHYT domain
BLi01496	COG5001	Diguanylate cyclase
BLi01497	COG0586	Pfam SNARE associated Golgi protein
BLi01498	COG0861	Integral membrane protein TerC family
BLi01499	COG1191	sigma factor activity
BLi01503	COG0501	Belongs to the peptidase M48B family
BLi01504	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BLi01505	COG0768	penicillin binding
BLi01508	COG3594	Acyltransferase
BLi01509	COG5002	protein histidine kinase activity
BLi01510	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BLi01511	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BLi01512	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BLi01513	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BLi01514	COG0436	Aminotransferase
BLi01515	COG1850	ribulose-bisphosphate carboxylase activity
BLi01516	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BLi01516	COG0235	Class ii aldolase
BLi01517	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BLi01518	COG0346	lactoylglutathione lyase activity
BLi01519	COG3339	Conserved Protein
BLi01521	COG3852	Histidine kinase
BLi01522	COG1846	Transcriptional regulator
BLi01523	COG1360	Flagellar Motor Protein
BLi01524	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BLi01525	COG0542	response to heat
BLi01526	COG3949	Membrane
BLi01527	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BLi01528	COG0720	synthase
BLi01529	COG0602	queuosine metabolic process
BLi01530	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BLi01531	COG4974	Belongs to the 'phage' integrase family
BLi01532	COG4974	Belongs to the 'phage' integrase family
BLi01538	COG1793	dna ligase
BLi01550	COG0740	serine-type endopeptidase activity
BLi01559	COG3953	SLT domain
BLi01559	COG5280	Phage tail tape measure protein TP901
BLi01566	COG0584	glycerophosphoryl diester phosphodiesterase
BLi01568	COG1388	LysM domain
BLi01568	COG5632	N-Acetylmuramoyl-L-alanine amidase
BLi01568	COG3409	Peptidoglycan-binding domain 1 protein
BLi01574	COG0582	viral genome integration into host DNA
BLi01577	COG0457	Tetratricopeptide repeat
BLi01578	COG0457	Tetratricopeptide repeat
BLi01579	COG3739	integral membrane protein
BLi01580	COG3655	Transcriptional regulator
BLi01588	COG4873	Protein conserved in bacteria
BLi01590	COG3773	Cell wall hydrolase
BLi01591	COG2244	polysaccharide biosynthetic process
BLi01592	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLi01593	COG2217	Heavy metal translocating P-type atpase
BLi01594	COG0006	proline dipeptidase activity
BLi01596	COG1609	Transcriptional regulator
BLi01597	COG3711	transcriptional antiterminator
BLi01598	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLi01598	COG1263	PTS System
BLi01598	COG2190	(PTS) system
BLi01599	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLi01600	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BLi01602	COG1533	DNA photolyase activity
BLi01603	COG0456	acetyltransferase
BLi01604	COG0840	transmembrane signaling receptor activity
BLi01605	COG1028	Short-chain dehydrogenase reductase Sdr
BLi01606	COG2084	Dehydrogenase
BLi01607	COG2340	Cysteine-rich secretory protein family
BLi01608	COG0768	penicillin binding
BLi01609	COG4191	Histidine kinase
BLi01610	COG0436	Aminotransferase
BLi01612	COG1714	RDD family
BLi01614	COG0835	chemotaxis
BLi01614	COG0784	Response regulator, receiver
BLi01616	COG2814	Major facilitator Superfamily
BLi01617	COG1376	ErfK ybiS ycfS ynhG family protein
BLi01619	COG1408	metallophosphoesterase
BLi01620	COG1028	Short-chain dehydrogenase reductase Sdr
BLi01621	COG2200	EAL domain
BLi01624	COG4703	Protein of unknown function (DUF1797)
BLi01625	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BLi01627	COG0517	IMP dehydrogenase activity
BLi01628	COG0583	DNA-binding transcription factor activity
BLi01629	COG0716	FMN binding
BLi01631	COG0716	FMN binding
BLi01632	COG2171	N-acyltransferase activity
BLi01633	COG1473	amidohydrolase
BLi01635	COG0450	alkyl hydroperoxide reductase
BLi01636	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLi01639	COG0746	molybdenum cofactor guanylyltransferase activity
BLi01640	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BLi01641	COG0303	'Molybdopterin
BLi01642	COG1763	Mo-molybdopterin cofactor biosynthetic process
BLi01643	COG0314	molybdopterin synthase activity
BLi01644	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BLi01646	COG1132	(ABC) transporter
BLi01647	COG1132	(ABC) transporter
BLi01649	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BLi01650	COG1136	(ABC) transporter
BLi01651	COG0577	efflux transmembrane transporter activity
BLi01652	COG1349	DNA-binding transcription factor activity
BLi01653	COG1105	Belongs to the carbohydrate kinase PfkB family
BLi01654	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BLi01654	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLi01654	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BLi01658	COG0488	(ABC) transporter
BLi01660	COG2309	aminopeptidase activity
BLi01662	COG1077	Cell shape determining protein MreB Mrl
BLi01664	COG2002	toxin-antitoxin pair type II binding
BLi01665	COG3852	Histidine kinase
BLi01666	COG0569	domain protein
BLi01667	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BLi01668	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BLi01670	COG0561	phosphatase activity
BLi01671	COG0242	peptide deformylase activity
BLi01673	COG0497	DNA recombination
BLi01674	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BLi01675	COG0022	dehydrogenase e1 component
BLi01676	COG0508	dehydrogenase complex catalyzes the overall conversion of
BLi01677	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BLi01678	COG2801	Transposase and inactivated derivatives
BLi01680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLi01681	COG1982	Orn Lys Arg decarboxylase major
BLi01682	COG4476	Belongs to the UPF0223 family
BLi01683	COG4493	Belongs to the UPF0637 family
BLi01685	COG0483	inositol monophosphate 1-phosphatase activity
BLi01689	COG1595	DNA-templated transcription, initiation
BLi01694	COG1846	Transcriptional regulator
BLi01695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BLi01696	COG4896	Protein conserved in bacteria
BLi01698	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BLi01699	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BLi01700	COG2066	Belongs to the glutaminase family
BLi01701	COG4838	Belongs to the UPF0358 family
BLi01702	COG0772	Belongs to the SEDS family
BLi01703	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BLi01704	COG1612	heme a metabolic process
BLi01705	COG0109	protoheme IX farnesyltransferase activity
BLi01706	COG2010	Cytochrome c
BLi01706	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BLi01707	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BLi01708	COG1845	cytochrome c oxidase, subunit III
BLi01709	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BLi01710	COG3336	cytochrome c oxidase
BLi01712	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BLi01713	COG2340	Cysteine-rich secretory protein family
BLi01716	COG3679	Belongs to the UPF0342 family
BLi01717	COG4471	UPF0298 protein
BLi01718	COG0742	ribosomal rna small subunit methyltransferase
BLi01719	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BLi01720	COG3314	Sporulation integral membrane protein YlbJ
BLi01722	COG3480	Lon protease (S16) C-terminal proteolytic domain
BLi01723	COG1323	Belongs to the UPF0348 family
BLi01724	COG1399	metal-binding, possibly nucleic acid-binding protein
BLi01725	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BLi01727	COG0454	-acetyltransferase
BLi01728	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BLi01729	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BLi01730	COG2001	Belongs to the MraZ family
BLi01731	COG0275	rRNA processing
BLi01732	COG4839	cell division protein FtsL
BLi01734	COG0768	penicillin binding
BLi01735	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BLi01736	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BLi01737	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BLi01738	COG0772	Belongs to the SEDS family
BLi01739	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BLi01740	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BLi01741	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BLi01742	COG3879	Bacterial protein of unknown function (DUF881)
BLi01743	COG3879	Bacterial protein of unknown function (DUF881)
BLi01744	COG3856	small basic protein
BLi01745	COG0849	cell division
BLi01746	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BLi01748	COG4412	M6 family metalloprotease domain protein
BLi01748	COG1404	Belongs to the peptidase S8 family
BLi01750	COG1191	sigma factor activity
BLi01751	COG1191	sigma factor activity
BLi01752	COG1119	ATPase activity
BLi01754	COG0500	methyltransferase
BLi01755	COG1873	PFAM PRC-barrel domain
BLi01757	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BLi01758	COG1799	cell septum assembly
BLi01759	COG0762	integral membrane protein
BLi01760	COG2302	S4 RNA-binding domain
BLi01761	COG3599	regulation of cell shape
BLi01762	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BLi01763	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BLi01765	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BLi01766	COG0564	pseudouridine synthase activity
BLi01767	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BLi01768	COG2233	PERMEase
BLi01769	COG0540	Belongs to the ATCase OTCase family
BLi01770	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BLi01771	COG0505	Belongs to the CarA family
BLi01772	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BLi01773	COG0543	2 iron, 2 sulfur cluster binding
BLi01774	COG0167	dihydroorotate dehydrogenase activity
BLi01775	COG0284	orotidine-5'-phosphate decarboxylase activity
BLi01776	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BLi01778	COG0175	sulfate reduction
BLi01779	COG0306	phosphate transporter
BLi01780	COG2046	Belongs to the sulfate adenylyltransferase family
BLi01781	COG0529	Catalyzes the synthesis of activated sulfate
BLi01782	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BLi01783	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
BLi01784	COG1648	precorrin-2 dehydrogenase activity
BLi01786	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BLi01787	COG1561	YicC-like family, N-terminal region
BLi01788	COG2052	Domain of unknown function (DUF370)
BLi01789	COG0194	GDP metabolic process
BLi01790	COG1758	RNA polymerase activity
BLi01791	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BLi01792	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BLi01793	COG0242	peptide deformylase activity
BLi01794	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BLi01795	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BLi01795	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BLi01796	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BLi01797	COG0631	protein serine/threonine phosphatase activity
BLi01798	COG2815	serine threonine protein kinase
BLi01798	COG0515	serine threonine protein kinase
BLi01799	COG1162	GTPase activity
BLi01800	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BLi01801	COG1564	THIamine pyrophosphokinase
BLi01803	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BLi01804	COG1302	Protein conserved in bacteria
BLi01805	COG1461	Dihydroxyacetone kinase
BLi01806	COG1760	l-serine dehydratase
BLi01807	COG1760	l-serine dehydratase
BLi01808	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BLi01809	COG1349	DNA-binding transcription factor activity
BLi01810	COG0416	fatty acid biosynthetic process
BLi01811	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BLi01812	COG1028	Short-chain dehydrogenase reductase Sdr
BLi01813	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BLi01814	COG0571	ribonuclease III activity
BLi01815	COG1196	nuclear chromosome segregation
BLi01816	COG0552	protein localization to endoplasmic reticulum
BLi01817	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BLi01818	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BLi01819	COG0228	four-way junction DNA binding
BLi01820	COG1837	Belongs to the UPF0109 family
BLi01822	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BLi01823	COG0336	Belongs to the RNA methyltransferase TrmD family
BLi01824	COG0335	large ribosomal subunit rRNA binding
BLi01825	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BLi01826	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BLi01828	COG2257	FlhB HrpN YscU SpaS Family
BLi01829	COG0045	succinate-CoA ligase (ADP-forming) activity
BLi01830	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BLi01831	COG0758	DNA mediated transformation
BLi01832	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BLi01833	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BLi01834	COG4974	Belongs to the 'phage' integrase family
BLi01835	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BLi01836	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BLi01837	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BLi01838	COG1815	bacterial-type flagellum-dependent cell motility
BLi01839	COG1558	bacterial-type flagellum-dependent cell motility
BLi01840	COG1677	Flagellar hook-basal body complex protein FliE
BLi01841	COG1766	The M ring may be actively involved in energy transduction
BLi01842	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BLi01843	COG1317	bacterial-type flagellum organization
BLi01844	COG1157	protein secretion by the type III secretion system
BLi01845	COG2882	bacterial-type flagellum organization
BLi01847	COG3144	bacterial-type flagellum assembly
BLi01848	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BLi01849	COG4786	Flagellar basal body rod
BLi01850	COG1582	Flagellar protein (FlbD)
BLi01851	COG1580	Controls the rotational direction of flagella during chemotaxis
BLi01852	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BLi01853	COG1776	CheC inhibitor of MCP methylation
BLi01853	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BLi01854	COG2201	protein-glutamate methylesterase activity
BLi01855	COG3190	flagellar
BLi01856	COG1338	Plays a role in the flagellum-specific transport system
BLi01857	COG1987	bacterial-type flagellum assembly
BLi01858	COG1684	flagellar biosynthetic protein fliR
BLi01859	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BLi01860	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BLi01861	COG1419	protein localization to endoplasmic reticulum
BLi01862	COG0455	bacterial-type flagellum organization
BLi01863	COG2201	protein-glutamate methylesterase activity
BLi01864	COG0643	Histidine kinase
BLi01864	COG2198	Histidine kinase
BLi01865	COG0835	chemotaxis
BLi01866	COG1776	CheC inhibitor of MCP methylation
BLi01867	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BLi01868	COG1191	sigma factor activity
BLi01870	COG0052	Belongs to the universal ribosomal protein uS2 family
BLi01871	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BLi01872	COG0528	UMP kinase activity
BLi01873	COG0233	cytoplasmic translational termination
BLi01874	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BLi01875	COG4589	Belongs to the CDS family
BLi01876	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BLi01877	COG0750	zinc metalloprotease
BLi01878	COG0442	prolyl-tRNA aminoacylation
BLi01879	COG2176	DNA-directed DNA polymerase activity
BLi01884	COG0779	Required for maturation of 30S ribosomal subunits
BLi01885	COG0195	Participates in both transcription termination and antitermination
BLi01886	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BLi01887	COG1358	cellular component organization or biogenesis
BLi01888	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BLi01889	COG1550	Protein conserved in bacteria
BLi01890	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BLi01891	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BLi01892	COG0196	riboflavin kinase activity
BLi01893	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BLi01894	COG1185	polyribonucleotide nucleotidyltransferase activity
BLi01895	COG0726	polysaccharide deacetylase
BLi01896	COG0612	Peptidase, M16
BLi01897	COG1873	PFAM PRC-barrel domain
BLi01898	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BLi01899	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BLi01900	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BLi01901	COG0527	aspartate kinase activity
BLi01903	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BLi01904	COG0740	serine-type endopeptidase activity
BLi01906	COG1674	ftsk spoiiie
BLi01906	COG4980	gas vesicle protein
BLi01907	COG2188	Transcriptional regulator
BLi01908	COG2814	Major facilitator Superfamily
BLi01909	COG0612	Peptidase, M16
BLi01910	COG0612	Peptidase, M16
BLi01911	COG0300	oxidoreductase activity
BLi01915	COG1426	Protein conserved in bacteria
BLi01916	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BLi01917	COG1546	Belongs to the CinA family
BLi01917	COG1058	Belongs to the CinA family
BLi01918	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BLi01919	COG1418	mRNA catabolic process
BLi01920	COG1692	metallophosphoesterase
BLi01921	COG2359	stage V sporulation protein S
BLi01923	COG1063	alcohol dehydrogenase
BLi01924	COG0156	8-amino-7-oxononanoate synthase activity
BLi01925	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BLi01926	COG4550	Control of competence regulator ComK, YlbF/YmcA
BLi01928	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BLi01929	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BLi01930	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BLi01931	COG5444	nuclease activity
BLi01933	COG0523	cobalamin synthesis protein
BLi01935	COG1247	-acetyltransferase
BLi01939	COG3619	membrane
BLi01940	COG3263	regulation of cellular component size
BLi01943	COG2267	carboxylic ester hydrolase activity
BLi01944	COG2267	carboxylic ester hydrolase activity
BLi01945	COG0393	Putative heavy-metal-binding
BLi01946	COG0398	Pfam SNARE associated Golgi protein
BLi01947	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BLi01948	COG1819	glycosyl
BLi01949	COG0531	amino acid
BLi01950	COG5577	PFAM Coat F domain
BLi01952	COG3858	chitin binding
BLi01952	COG1388	LysM domain
BLi01953	COG1309	transcriptional regulator
BLi01954	COG3631	Ketosteroid isomerase-related protein
BLi01955	COG0702	epimerase
BLi01957	COG1764	response to oxidative stress
BLi01958	COG2076	Multidrug Resistance protein
BLi01959	COG2076	Multidrug Resistance protein
BLi01961	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BLi01962	COG1923	regulation of RNA biosynthetic process
BLi01965	COG1780	Probably involved in ribonucleotide reductase function
BLi01966	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BLi01967	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BLi01968	COG4112	unkown
BLi01971	COG0735	belongs to the Fur family
BLi01972	COG1802	Transcriptional regulator
BLi01973	COG0697	spore germination
BLi01979	COG1309	transcriptional regulator
BLi01989	COG0464	growth
BLi01990	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BLi01991	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BLi01992	COG0789	Transcriptional regulator
BLi01993	COG0174	glutamine synthetase
BLi02000	COG1073	alpha beta
BLi02009	COG1309	transcriptional regulator
BLi02010	COG2076	Multidrug Resistance protein
BLi02011	COG2076	Multidrug Resistance protein
BLi02012	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BLi02016	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLi02017	COG3546	catalase activity
BLi02022	COG1846	Transcriptional regulator
BLi02023	COG0778	Nitroreductase
BLi02024	COG0346	lactoylglutathione lyase activity
BLi02025	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BLi02026	COG0655	NAD(P)H dehydrogenase (quinone) activity
BLi02029	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BLi02030	COG3209	COG3209 Rhs family protein
BLi02032	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BLi02033	COG1388	LysM domain
BLi02034	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BLi02035	COG4224	UPF0291 protein
BLi02036	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BLi02038	COG3763	UPF0154 protein
BLi02040	COG0785	Cytochrome C biogenesis protein
BLi02041	COG2201	protein-glutamate methylesterase activity
BLi02042	COG4846	Membrane protein involved in cytochrome C biogenesis
BLi02044	COG0071	Belongs to the small heat shock protein (HSP20) family
BLi02047	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BLi02048	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLi02052	COG0824	Thioesterase
BLi02056	COG4841	protein insertion into membrane
BLi02057	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BLi02058	COG1832	CoA-binding protein
BLi02059	COG0187	DNA topoisomerase II activity
BLi02060	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BLi02061	COG1609	Transcriptional regulator
BLi02064	COG2160	L-arabinose isomerase activity
BLi02069	COG1115	amino acid carrier protein
BLi02071	COG2181	nitrate reductase activity
BLi02072	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BLi02073	COG1140	nitrate reductase beta subunit
BLi02074	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BLi02078	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BLi02080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BLi02081	COG2223	nitrite transmembrane transporter activity
BLi02085	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BLi02088	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BLi02090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BLi02092	COG0492	ferredoxin-NADP+ reductase activity
BLi02095	COG3420	alginic acid biosynthetic process
BLi02096	COG1114	Component of the transport system for branched-chain amino acids
BLi02097	COG1064	alcohol dehydrogenase
BLi02098	COG0789	Transcriptional regulator
BLi02103	COG1024	Enoyl-CoA hydratase
BLi02104	COG1012	belongs to the aldehyde dehydrogenase family
BLi02105	COG2084	Dehydrogenase
BLi02106	COG1960	acyl-CoA dehydrogenase activity
BLi02107	COG1482	cell wall glycoprotein biosynthetic process
BLi02108	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BLi02108	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLi02108	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BLi02111	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLi02111	COG3711	transcriptional antiterminator
BLi02114	COG1725	Transcriptional regulator
BLi02115	COG1028	Short-chain dehydrogenase reductase Sdr
BLi02116	COG1312	Catalyzes the dehydration of D-mannonate
BLi02119	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BLi02121	COG1609	Transcriptional regulator
BLi02122	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BLi02123	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BLi02124	COG0640	Transcriptional regulator
BLi02126	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BLi02129	COG1649	PFAM Uncharacterised BCR, COG1649
BLi02130	COG2404	hydrolase activity, acting on ester bonds
BLi02131	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BLi02133	COG2027	D-alanyl-D-alanine carboxypeptidase
BLi02134	COG1252	NADH dehydrogenase
BLi02136	COG0166	Belongs to the GPI family
BLi02138	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BLi02139	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BLi02140	COG1024	Enoyl-CoA hydratase
BLi02141	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BLi02142	COG0511	ligase activity, forming carbon-carbon bonds
BLi02143	COG0439	Biotin carboxylase
BLi02144	COG0318	PFAM AMP-dependent synthetase and ligase
BLi02145	COG1960	acyl-CoA dehydrogenase activity
BLi02146	COG2249	NAD(P)H dehydrogenase (quinone) activity
BLi02147	COG1733	regulation of RNA biosynthetic process
BLi02148	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BLi02149	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BLi02151	COG2323	membrane
BLi02153	COG0306	phosphate transporter
BLi02154	COG0175	sulfate reduction
BLi02155	COG1809	phosphosulfolactate synthase activity
BLi02156	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BLi02157	COG4948	Mandelate Racemase Muconate Lactonizing
BLi02158	COG2814	Major facilitator Superfamily
BLi02159	COG0463	Glycosyl transferase, family 2
BLi02161	COG0493	'glutamate synthase
BLi02162	COG0069	glutamate synthase activity
BLi02162	COG0067	glutamate synthase
BLi02162	COG0070	glutamate synthase
BLi02163	COG0583	DNA-binding transcription factor activity
BLi02167	COG1846	Transcriptional regulator
BLi02169	COG1132	(ABC) transporter
BLi02171	COG0300	oxidoreductase activity
BLi02172	COG3848	Pyruvate phosphate dikinase
BLi02172	COG0574	Belongs to the PEP-utilizing enzyme family
BLi02173	COG0477	Major facilitator Superfamily
BLi02174	COG0243	molybdopterin cofactor binding
BLi02175	COG1846	Transcriptional regulator
BLi02176	COG2814	Major facilitator Superfamily
BLi02177	COG0531	amino acid
BLi02179	COG0531	amino acid
BLi02180	COG0531	amino acid
BLi02181	COG0697	spore germination
BLi02183	COG0840	transmembrane signaling receptor activity
BLi02184	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BLi02185	COG1404	Belongs to the peptidase S8 family
BLi02187	COG1309	transcriptional regulator
BLi02188	COG1846	Transcriptional regulator
BLi02194	COG1309	transcriptional regulator
BLi02195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BLi02196	COG3708	Transcriptional regulator
BLi02199	COG2378	regulation of single-species biofilm formation
BLi02201	COG0640	Transcriptional regulator
BLi02202	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BLi02203	COG0531	amino acid
BLi02204	COG0741	lytic transglycosylase activity
BLi02205	COG1086	Polysaccharide biosynthesis protein
BLi02209	COG2322	membrane
BLi02212	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BLi02213	COG1388	LysM domain
BLi02213	COG3584	3D domain protein
BLi02214	COG0514	ATP-dependent DNA helicase (RecQ)
BLi02218	COG2315	Protein conserved in bacteria
BLi02221	COG2427	Protein of unknown function (DUF1641)
BLi02222	COG3383	formate dehydrogenase (NAD+) activity
BLi02226	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BLi02233	COG0402	S-adenosylhomocysteine deaminase activity
BLi02236	COG2267	carboxylic ester hydrolase activity
BLi02238	COG1280	lysine exporter protein (LysE YggA)
BLi02239	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BLi02241	COG0574	Belongs to the PEP-utilizing enzyme family
BLi02241	COG3848	Pyruvate phosphate dikinase
BLi02242	COG1309	transcriptional regulator
BLi02244	COG2318	DinB family
BLi02245	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BLi02246	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BLi02249	COG1012	belongs to the aldehyde dehydrogenase family
BLi02250	COG2814	Major facilitator Superfamily
BLi02253	COG1657	PFAM Prenyltransferase squalene oxidase
BLi02254	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BLi02256	COG0733	neurotransmitter:sodium symporter activity
BLi02258	COG0385	Bile acid
BLi02259	COG0508	dehydrogenase complex catalyzes the overall conversion of
BLi02260	COG0567	Dehydrogenase, E1 component
BLi02261	COG4548	von Willebrand factor, type A
BLi02262	COG0714	Associated with various cellular activities
BLi02263	COG2032	superoxide dismutase activity
BLi02264	COG1388	LysM domain
BLi02264	COG0791	NLP P60 protein
BLi02265	COG0534	Mate efflux family protein
BLi02266	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BLi02267	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BLi02269	COG2962	Rard protein
BLi02271	COG4305	rare lipoprotein A
BLi02273	COG1028	Short-chain dehydrogenase reductase Sdr
BLi02274	COG1733	regulation of RNA biosynthetic process
BLi02275	COG0778	Nitroreductase
BLi02276	COG0400	carboxylic ester hydrolase activity
BLi02278	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BLi02280	COG2801	Transposase and inactivated derivatives
BLi02281	COG3409	Peptidoglycan-binding domain 1 protein
BLi02281	COG0793	Belongs to the peptidase S41A family
BLi02282	COG2226	methyltransferase
BLi02284	COG1876	peptidase activity
BLi02285	COG0813	purine-nucleoside phosphorylase activity
BLi02286	COG0701	Predicted permease
BLi02289	COG0671	phosphoesterase, PA-phosphatase related
BLi02292	COG4479	Belongs to the UPF0346 family
BLi02294	COG1509	lysine 2,3-aminomutase activity
BLi02295	COG0456	acetyltransferase
BLi02296	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BLi02297	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BLi02298	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BLi02299	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BLi02301	COG0456	acetyltransferase
BLi02302	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BLi02303	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BLi02304	COG1846	Transcriptional regulator
BLi02306	COG3706	GGDEF domain
BLi02307	COG0534	Mate efflux family protein
BLi02310	COG4698	Protein conserved in bacteria
BLi02311	COG2755	lipolytic protein G-D-S-L family
BLi02312	COG1999	signal sequence binding
BLi02315	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BLi02316	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BLi02317	COG1272	protein, Hemolysin III
BLi02318	COG0204	Acyl-transferase
BLi02319	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BLi02320	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BLi02322	COG2136	Putative SAM-dependent methyltransferase
BLi02322	COG2521	methyltransferase
BLi02324	COG0129	dihydroxy-acid dehydratase activity
BLi02325	COG1413	lyase activity
BLi02326	COG1418	mRNA catabolic process
BLi02327	COG0386	Belongs to the glutathione peroxidase family
BLi02328	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BLi02329	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BLi02330	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BLi02332	COG1278	Cold shock
BLi02336	COG0328	RNA-DNA hybrid ribonuclease activity
BLi02337	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BLi02338	COG0328	RNA-DNA hybrid ribonuclease activity
BLi02340	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BLi02343	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BLi02344	COG1755	Isoprenylcysteine carboxyl methyltransferase
BLi02345	COG3424	synthase
BLi02346	COG0456	acetyltransferase
BLi02347	COG2233	PERMEase
BLi02348	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BLi02349	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BLi02350	COG1199	ATP-dependent helicase activity
BLi02353	COG0116	Belongs to the methyltransferase superfamily
BLi02354	COG3599	regulation of cell shape
BLi02355	COG4474	Belongs to the UPF0398 family
BLi02357	COG3359	exonuclease
BLi02358	COG1205	dead DEAH box helicase
BLi02358	COG1111	helicase
BLi02359	COG2190	(PTS) system
BLi02360	COG0071	Belongs to the small heat shock protein (HSP20) family
BLi02366	COG3331	DNA recombination
BLi02367	COG4499	WXG100 protein secretion system (Wss), protein YukC
BLi02367	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BLi02369	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BLi02370	COG3935	DnaD domain protein
BLi02371	COG0017	Asparaginyl-tRNA synthetase
BLi02372	COG0436	Aminotransferase
BLi02373	COG5353	protein conserved in bacteria
BLi02375	COG1199	ATP-dependent helicase activity
BLi02375	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BLi02376	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BLi02377	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BLi02378	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BLi02380	COG0617	tRNA 3'-terminal CCA addition
BLi02381	COG0438	transferase activity, transferring glycosyl groups
BLi02382	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BLi02383	COG1803	Methylglyoxal synthase
BLi02384	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BLi02385	COG1694	Mazg nucleotide pyrophosphohydrolase
BLi02386	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BLi02388	COG4347	Protein of unknown function (DUF1405)
BLi02389	COG2010	Cytochrome c
BLi02389	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BLi02390	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BLi02391	COG0723	plastoquinol--plastocyanin reductase activity
BLi02393	COG5582	Belongs to the UPF0302 family
BLi02394	COG0457	Tetratricopeptide repeat
BLi02395	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BLi02396	COG0287	Prephenate dehydrogenase
BLi02397	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BLi02398	COG0159	tryptophan synthase activity
BLi02399	COG0133	tryptophan synthase activity
BLi02400	COG0135	phosphoribosylanthranilate isomerase activity
BLi02401	COG0134	indole-3-glycerol-phosphate synthase activity
BLi02402	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BLi02403	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BLi02404	COG4401	Chorismate mutase type I
BLi02405	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BLi02406	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BLi02407	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BLi02408	COG0105	UTP biosynthetic process
BLi02409	COG0142	geranyltranstransferase activity
BLi02410	COG2226	methyltransferase
BLi02411	COG0142	geranyltranstransferase activity
BLi02414	COG0776	regulation of translation
BLi02416	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BLi02420	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BLi02421	COG1160	GTP binding
BLi02426	COG1304	FMN binding
BLi02427	COG0539	negative regulation of cytoplasmic translation
BLi02428	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BLi02430	COG2959	enzyme of heme biosynthesis
BLi02431	COG3409	Peptidoglycan-binding domain 1 protein
BLi02431	COG3773	Cell wall hydrolase
BLi02432	COG2339	peptidase activity
BLi02434	COG0492	ferredoxin-NADP+ reductase activity
BLi02435	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BLi02436	COG4862	establishment of competence for transformation
BLi02437	COG1408	metallophosphoesterase
BLi02439	COG1388	LysM domain
BLi02440	COG1266	CAAX protease self-immunity
BLi02441	COG0514	ATP-dependent DNA helicase (RecQ)
BLi02442	COG4955	Helix-turn-helix domain
BLi02443	COG1141	Ferredoxin
BLi02444	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BLi02446	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BLi02449	COG1595	DNA-templated transcription, initiation
BLi02454	COG5002	protein histidine kinase activity
BLi02455	COG0745	RESPONSE REGULATOR receiver
BLi02456	COG5002	protein histidine kinase activity
BLi02458	COG0745	RESPONSE REGULATOR receiver
BLi02459	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BLi02460	COG1333	cytochrome c biogenesis protein
BLi02461	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLi02462	COG1187	pseudouridine synthase activity
BLi02463	COG0700	Nucleoside recognition
BLi02464	COG2715	membrane protein required for spore maturation
BLi02465	COG1686	Belongs to the peptidase S11 family
BLi02467	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BLi02468	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BLi02470	COG1547	Domain of unknown function (DUF309)
BLi02471	COG0456	acetyltransferase
BLi02472	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BLi02473	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BLi02473	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BLi02474	COG0307	riboflavin synthase, alpha
BLi02475	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BLi02475	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BLi02480	COG0457	Tetratricopeptide repeat
BLi02481	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BLi02482	COG4086	secreted protein
BLi02484	COG2801	Transposase and inactivated derivatives
BLi02485	COG4195	phage-related replication protein
BLi02486	COG0019	diaminopimelate decarboxylase activity
BLi02488	COG0697	spore germination
BLi02491	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BLi02496	COG2172	sigma factor antagonist activity
BLi02498	COG1686	Belongs to the peptidase S11 family
BLi02499	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BLi02500	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BLi02501	COG4974	Belongs to the 'phage' integrase family
BLi02503	COG0735	belongs to the Fur family
BLi02504	COG1300	Membrane
BLi02505	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BLi02510	COG2153	protein acetylation
BLi02511	COG1379	DNA repair
BLi02512	COG0494	nUDIX hydrolase
BLi02514	COG1309	transcriptional regulator
BLi02516	COG0667	Aldo Keto reductase
BLi02519	COG1073	alpha beta
BLi02521	COG4918	Iron-sulphur cluster biosynthesis
BLi02523	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BLi02523	COG0456	acetyltransferase
BLi02524	COG2329	Antibiotic biosynthesis monooxygenase
BLi02525	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BLi02527	COG0747	negative chemotaxis
BLi02528	COG0601	transmembrane transport
BLi02529	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BLi02530	COG0444	Belongs to the ABC transporter superfamily
BLi02532	COG0534	Mate efflux family protein
BLi02536	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BLi02538	COG2211	Major facilitator Superfamily
BLi02539	COG0346	lactoylglutathione lyase activity
BLi02540	COG1072	(Pantothenic acid kinase))
BLi02546	COG4195	phage-related replication protein
BLi02547	COG0300	oxidoreductase activity
BLi02548	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BLi02549	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BLi02550	COG4187	Peptidase family M20/M25/M40
BLi02551	COG1902	pentaerythritol trinitrate reductase activity
BLi02552	COG0596	Alpha beta hydrolase
BLi02553	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BLi02554	COG1234	tRNA 3'-trailer cleavage
BLi02555	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BLi02559	COG2188	Transcriptional regulator
BLi02560	COG2723	6-phospho-beta-galactosidase activity
BLi02563	COG1447	Phosphotransferase system cellobiose-specific component IIA
BLi02564	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BLi02565	COG1785	Belongs to the alkaline phosphatase family
BLi02566	COG1028	Short-chain dehydrogenase reductase Sdr
BLi02567	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BLi02568	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BLi02570	COG0706	membrane insertase activity
BLi02571	COG2195	Cleaves the N-terminal amino acid of tripeptides
BLi02572	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BLi02573	COG4129	membrane
BLi02574	COG1126	abc transporter atp-binding protein
BLi02575	COG0765	amino acid transport
BLi02579	COG1597	lipid kinase activity
BLi02580	COG0508	dehydrogenase complex catalyzes the overall conversion of
BLi02581	COG0022	dehydrogenase e1 component
BLi02582	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BLi02583	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BLi02584	COG3426	butyrate kinase activity
BLi02586	COG0280	phosphate acetyltransferase
BLi02587	COG3290	protein histidine kinase activity
BLi02587	COG3829	transcription factor binding
BLi02589	COG0584	glycerophosphoryl diester phosphodiesterase
BLi02590	COG0860	N-Acetylmuramoyl-L-alanine amidase
BLi02592	COG1045	serine acetyltransferase
BLi02593	COG0745	RESPONSE REGULATOR receiver
BLi02594	COG0750	zinc metalloprotease
BLi02595	COG0497	DNA recombination
BLi02596	COG1438	arginine binding
BLi02597	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BLi02598	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BLi02599	COG0142	geranyltranstransferase activity
BLi02600	COG1722	exodeoxyribonuclease VII activity
BLi02601	COG1570	exodeoxyribonuclease VII activity
BLi02602	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BLi02603	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BLi02604	COG1302	Protein conserved in bacteria
BLi02605	COG0439	Biotin carboxylase
BLi02606	COG0511	ligase activity, forming carbon-carbon bonds
BLi02614	COG3854	ATPases associated with a variety of cellular activities
BLi02616	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BLi02617	COG0006	proline dipeptidase activity
BLi02618	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BLi02620	COG3872	metal-dependent enzyme
BLi02622	COG1752	Esterase of the alpha-beta hydrolase superfamily
BLi02623	COG1321	iron dependent repressor
BLi02624	COG0095	Lipoate-protein ligase
BLi02625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BLi02626	COG2113	Glycine betaine
BLi02627	COG4176	ABC-type proline glycine betaine transport system permease component
BLi02628	COG0517	IMP dehydrogenase activity
BLi02628	COG4175	Glycine betaine
BLi02629	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BLi02630	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BLi02631	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BLi02633	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BLi02638	COG0681	Belongs to the peptidase S26 family
BLi02643	COG4940	Competence protein ComGF
BLi02645	COG4970	Tfp pilus assembly protein FimT
BLi02646	COG4537	Required for transformation and DNA binding
BLi02647	COG1459	type II secretion system
BLi02648	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BLi02649	COG1366	Belongs to the anti-sigma-factor antagonist family
BLi02651	COG1393	Belongs to the ArsC family
BLi02653	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BLi02655	COG0011	TIGRFAM Protein of
BLi02657	COG2866	Carboxypeptidase
BLi02658	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BLi02659	COG1368	sulfuric ester hydrolase activity
BLi02660	COG1940	carbohydrate kinase activity
BLi02661	COG4483	Protein conserved in bacteria
BLi02663	COG0697	spore germination
BLi02664	COG0705	Rhomboid family
BLi02664	COG0457	Tetratricopeptide repeat
BLi02666	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BLi02667	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BLi02668	COG0438	transferase activity, transferring glycosyl groups
BLi02671	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BLi02672	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BLi02673	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BLi02674	COG0581	inorganic phosphate transmembrane transporter activity
BLi02675	COG0573	inorganic phosphate transmembrane transporter activity
BLi02676	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BLi02678	COG0477	Major facilitator Superfamily
BLi02679	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BLi02680	COG2839	Protein conserved in bacteria
BLi02681	COG5521	maltodextrose utilization protein MalA
BLi02682	COG1388	LysM domain
BLi02683	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BLi02684	COG4709	membrane
BLi02685	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BLi02686	COG0735	belongs to the Fur family
BLi02687	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BLi02688	COG1121	(ABC) transporter
BLi02690	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BLi02692	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BLi02693	COG0513	Belongs to the DEAD box helicase family
BLi02695	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BLi02696	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BLi02697	COG2384	SAM-dependent methyltransferase
BLi02707	COG5444	nuclease activity
BLi02710	COG2010	Cytochrome c
BLi02712	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BLi02713	COG0358	DNA primase activity
BLi02714	COG1671	Belongs to the UPF0178 family
BLi02715	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BLi02716	COG0517	IMP dehydrogenase activity
BLi02717	COG0751	glycine-tRNA ligase activity
BLi02718	COG0752	glycyl-tRNA synthetase alpha subunit
BLi02719	COG1381	Involved in DNA repair and RecF pathway recombination
BLi02720	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BLi02721	COG0295	cytidine deaminase activity
BLi02722	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BLi02723	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BLi02724	COG1480	7TM receptor with intracellular HD hydrolase
BLi02725	COG1702	phosphate starvation-inducible protein PhoH
BLi02726	COG0561	phosphatase activity
BLi02729	COG4864	UPF0365 protein
BLi02730	COG1030	water channel activity
BLi02731	COG1610	YqeY-like protein
BLi02732	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BLi02733	COG1283	sodium-dependent phosphate transmembrane transporter activity
BLi02734	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BLi02735	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BLi02736	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BLi02737	COG2264	protein methyltransferase activity
BLi02738	COG0484	heat shock protein binding
BLi02739	COG0443	Heat shock 70 kDa protein
BLi02740	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BLi02741	COG1420	regulation of RNA biosynthetic process
BLi02742	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BLi02743	COG0481	GTPase activity
BLi02745	COG0860	N-Acetylmuramoyl-L-alanine amidase
BLi02746	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BLi02747	COG0268	Binds directly to 16S ribosomal RNA
BLi02748	COG1466	dna polymerase III delta subunit
BLi02750	COG2333	competence protein COMEC
BLi02750	COG0658	competence protein
BLi02751	COG2131	deaminase
BLi02752	COG1596	polysaccharide export
BLi02752	COG1555	photosystem II stabilization
BLi02753	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BLi02754	COG2226	methyltransferase
BLi02755	COG0799	negative regulation of ribosome biogenesis
BLi02756	COG1713	HD superfamily hydrolase involved in NAD metabolism
BLi02757	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BLi02758	COG1534	Rna-binding protein
BLi02759	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BLi02760	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BLi02761	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BLi02763	COG2755	lipolytic protein G-D-S-L family
BLi02764	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BLi02765	COG5609	conserved protein (DUF2294)
BLi02766	COG3383	formate dehydrogenase (NAD+) activity
BLi02767	COG2427	Protein of unknown function (DUF1641)
BLi02771	COG1247	-acetyltransferase
BLi02774	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BLi02776	COG0251	oxidation-reduction process
BLi02779	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BLi02780	COG0251	oxidation-reduction process
BLi02784	COG4978	Transcriptional regulator
BLi02784	COG0789	Transcriptional regulator
BLi02787	COG2197	response regulator
BLi02788	COG4585	Histidine kinase
BLi02789	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLi02790	COG0730	response to heat
BLi02791	COG0425	Belongs to the sulfur carrier protein TusA family
BLi02792	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BLi02792	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BLi02793	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BLi02793	COG0425	Belongs to the sulfur carrier protein TusA family
BLi02794	COG2210	Belongs to the sulfur carrier protein TusA family
BLi02795	COG1937	Protein conserved in bacteria
BLi02802	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BLi02803	COG0113	porphobilinogen synthase activity
BLi02804	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BLi02805	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BLi02806	COG1733	regulation of RNA biosynthetic process
BLi02807	COG3239	Fatty acid desaturase
BLi02808	COG4585	Histidine kinase
BLi02809	COG2197	response regulator
BLi02810	COG0492	ferredoxin-NADP+ reductase activity
BLi02811	COG0747	negative chemotaxis
BLi02812	COG0601	transmembrane transport
BLi02814	COG0444	Belongs to the ABC transporter superfamily
BLi02815	COG4608	Belongs to the ABC transporter superfamily
BLi02819	COG1028	Short-chain dehydrogenase reductase Sdr
BLi02822	COG2124	cytochrome p450
BLi02823	COG0730	response to heat
BLi02826	COG1028	Short-chain dehydrogenase reductase Sdr
BLi02827	COG1621	beta-fructofuranosidase activity
BLi02828	COG3716	PTS system mannose fructose sorbose family IID component
BLi02829	COG3715	PTS system
BLi02830	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLi02831	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLi02832	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BLi02832	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BLi02836	COG2169	Transcriptional regulator
BLi02837	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BLi02838	COG0656	L-ascorbic acid biosynthetic process
BLi02839	COG2814	Major facilitator Superfamily
BLi02840	COG1733	regulation of RNA biosynthetic process
BLi02841	COG3340	Belongs to the peptidase S51 family
BLi02842	COG1587	Uroporphyrinogen-III synthase
BLi02844	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BLi02845	COG0583	DNA-binding transcription factor activity
BLi02846	COG2814	Major facilitator Superfamily
BLi02848	COG2124	cytochrome p450
BLi02848	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BLi02849	COG1309	transcriptional regulator
BLi02850	COG1404	Belongs to the peptidase S8 family
BLi02851	COG2226	methyltransferase
BLi02853	COG0626	cystathionine gamma-synthase activity
BLi02854	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BLi02855	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BLi02856	COG2226	methyltransferase
BLi02859	COG0768	penicillin binding
BLi02860	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BLi02861	COG0572	uridine kinase
BLi02865	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BLi02866	COG3906	Belongs to the UPF0473 family
BLi02867	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BLi02868	COG4472	Bacterial protein of unknown function (DUF965)
BLi02869	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BLi02870	COG0628	permease
BLi02872	COG3881	PFAM PRC-barrel domain
BLi02873	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BLi02874	COG0457	Tetratricopeptide repeat
BLi02875	COG0482	sulfurtransferase activity
BLi02876	COG1104	cysteine desulfurase activity
BLi02877	COG1959	2 iron, 2 sulfur cluster binding
BLi02878	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BLi02879	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BLi02881	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BLi02882	COG0124	histidyl-tRNA synthetase
BLi02884	COG3103	Sh3 type 3 domain protein
BLi02884	COG4991	sh3 domain protein
BLi02884	COG0860	N-Acetylmuramoyl-L-alanine amidase
BLi02886	COG1490	D-aminoacyl-tRNA deacylase activity
BLi02887	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BLi02888	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BLi02889	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BLi02889	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BLi02890	COG5416	Lipopolysaccharide assembly protein A domain
BLi02891	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BLi02891	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BLi02893	COG2244	polysaccharide biosynthetic process
BLi02894	COG2323	membrane
BLi02896	COG1862	Preprotein translocase
BLi02897	COG0343	queuine tRNA-ribosyltransferase activity
BLi02898	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BLi02900	COG2255	four-way junction helicase activity
BLi02901	COG0632	four-way junction helicase activity
BLi02903	COG2112	serine threonine protein kinase
BLi02905	COG2318	DinB family
BLi02906	COG4195	phage-related replication protein
BLi02909	COG0217	transcriptional regulatory protein
BLi02911	COG1388	LysM domain
BLi02912	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BLi02913	COG0157	Belongs to the NadC ModD family
BLi02914	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BLi02915	COG1104	cysteine desulfurase activity
BLi02916	COG1827	regulation of RNA biosynthetic process
BLi02917	COG0077	Prephenate dehydratase
BLi02918	COG4492	Belongs to the UPF0735 family
BLi02919	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BLi02920	COG3290	protein histidine kinase activity
BLi02921	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BLi02922	COG2868	ribosomal protein
BLi02923	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BLi02924	COG1994	Peptidase M50
BLi02925	COG0739	heme binding
BLi02926	COG3832	glyoxalase III activity
BLi02927	COG0640	Transcriptional regulator
BLi02928	COG2894	cell division
BLi02929	COG0850	regulation of cytokinetic process
BLi02930	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BLi02931	COG1792	Involved in formation and maintenance of cell shape
BLi02932	COG1077	Cell shape determining protein MreB Mrl
BLi02933	COG2003	Belongs to the UPF0758 family
BLi02934	COG0424	maF-like protein
BLi02936	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BLi02937	COG0285	dihydrofolate synthase activity
BLi02938	COG0525	valine-tRNA ligase activity
BLi02940	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BLi02941	COG1388	LysM domain
BLi02942	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BLi02943	COG0113	porphobilinogen synthase activity
BLi02944	COG1587	Uroporphyrinogen-III synthase
BLi02945	COG0181	hydroxymethylbilane synthase activity
BLi02946	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BLi02947	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BLi02949	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BLi02950	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BLi02951	COG1067	ATP-dependent peptidase activity
BLi02951	COG0470	DNA polymerase III
BLi02952	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BLi02953	COG0544	peptidyl-prolyl cis-trans isomerase activity
BLi02954	COG0457	Tetratricopeptide repeat
BLi02954	COG1477	protein flavinylation
BLi02955	COG0066	3-isopropylmalate dehydratase activity
BLi02956	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BLi02957	COG0473	3-isopropylmalate dehydrogenase activity
BLi02958	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BLi02959	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BLi02960	COG0440	acetolactate synthase activity
BLi02961	COG0028	Belongs to the TPP enzyme family
BLi02962	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BLi02967	COG5518	Phage portal protein
BLi02968	COG1783	phage Terminase large subunit
BLi02977	COG5444	nuclease activity
BLi02978	COG0457	Tetratricopeptide repeat
BLi02983	COG0622	Phosphoesterase
BLi02984	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BLi02985	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BLi02986	COG5401	PFAM Sporulation and spore germination
BLi02987	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BLi02988	COG1846	Transcriptional regulator
BLi02989	COG2197	response regulator
BLi02990	COG4221	oxidoreductase activity
BLi02991	COG0824	Thioesterase
BLi02992	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BLi02993	COG1053	succinate dehydrogenase
BLi02994	COG2009	succinate dehydrogenase
BLi02995	COG1719	4-vinyl reductase, 4VR
BLi02996	COG0527	aspartate kinase activity
BLi02997	COG0322	excinuclease ABC activity
BLi02998	COG3118	belongs to the thioredoxin family
BLi02999	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BLi03000	COG2086	electron transfer activity
BLi03001	COG1024	Enoyl-CoA hydratase
BLi03002	COG1309	transcriptional regulator
BLi03003	COG0318	PFAM AMP-dependent synthetase and ligase
BLi03004	COG3766	membrane
BLi03005	COG1193	negative regulation of DNA recombination
BLi03006	COG1796	DNA polymerase
BLi03006	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BLi03007	COG1286	toxin biosynthetic process
BLi03008	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BLi03009	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BLi03013	COG1137	ATPase activity
BLi03015	COG0072	phenylalanine-tRNA ligase activity
BLi03015	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BLi03016	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BLi03017	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BLi03019	COG1966	Carbon starvation protein
BLi03022	COG0395	ABC-type sugar transport system, permease component
BLi03023	COG1175	transmembrane transport
BLi03024	COG1653	transport
BLi03025	COG0371	Dehydrogenase
BLi03026	COG0235	Class ii aldolase
BLi03027	COG1069	ribulokinase activity
BLi03028	COG2160	L-arabinose isomerase activity
BLi03029	COG3507	Belongs to the glycosyl hydrolase 43 family
BLi03030	COG1363	Peptidase, m42
BLi03032	COG3326	Membrane
BLi03033	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BLi03034	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BLi03035	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BLi03036	COG1346	cytolysis
BLi03038	COG3540	Alkaline phosphatase
BLi03039	COG3279	Response regulator of the LytR AlgR family
BLi03040	COG3275	phosphorelay sensor kinase activity
BLi03043	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BLi03045	COG0398	Pfam SNARE associated Golgi protein
BLi03046	COG1484	DNA-dependent DNA replication
BLi03047	COG3611	Membrane attachment protein
BLi03048	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BLi03051	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BLi03052	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BLi03053	COG3866	Pectate lyase
BLi03054	COG0237	dephospho-CoA kinase activity
BLi03055	COG1971	Probably functions as a manganese efflux pump
BLi03056	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BLi03057	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BLi03057	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BLi03058	COG5002	protein histidine kinase activity
BLi03059	COG0745	RESPONSE REGULATOR receiver
BLi03060	COG0039	L-malate dehydrogenase activity
BLi03061	COG0538	isocitrate dehydrogenase activity
BLi03062	COG0372	Belongs to the citrate synthase family
BLi03063	COG2707	UPF0756 membrane protein
BLi03064	COG0628	permease
BLi03065	COG3030	protein affecting phage T7 exclusion by the F plasmid
BLi03068	COG0205	6-phosphofructokinase activity
BLi03069	COG0825	malonyl-CoA metabolic process
BLi03070	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BLi03071	COG0281	malic enzyme
BLi03072	COG0587	DNA-directed DNA polymerase activity
BLi03076	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BLi03078	COG4109	DRTGG domain
BLi03079	COG1695	Transcriptional regulator
BLi03080	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BLi03081	COG1028	Short-chain dehydrogenase reductase Sdr
BLi03083	COG0165	Argininosuccinate lyase
BLi03084	COG0137	argininosuccinate synthase activity
BLi03085	COG0521	Mo-molybdopterin cofactor biosynthetic process
BLi03086	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BLi03087	COG0827	DNA restriction-modification system
BLi03088	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BLi03089	COG3874	Sporulation protein YtfJ
BLi03091	COG1714	RDD family
BLi03092	COG0616	signal peptide processing
BLi03093	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BLi03095	COG1566	PFAM secretion protein HlyD family protein
BLi03096	COG0477	Major facilitator Superfamily
BLi03098	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BLi03100	COG0301	tRNA thio-modification
BLi03101	COG1104	cysteine desulfurase activity
BLi03102	COG1114	Component of the transport system for branched-chain amino acids
BLi03104	COG2801	Transposase and inactivated derivatives
BLi03105	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BLi03106	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BLi03107	COG1309	transcriptional regulator
BLi03108	COG1956	GAF domain-containing protein
BLi03109	COG2199	diguanylate cyclase activity
BLi03109	COG2203	Gaf domain
BLi03111	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BLi03114	COG3152	Membrane
BLi03115	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BLi03116	COG1522	sequence-specific DNA binding
BLi03118	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BLi03119	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BLi03120	COG0454	-acetyltransferase
BLi03121	COG0517	IMP dehydrogenase activity
BLi03122	COG0123	including yeast histone deacetylase and acetoin utilization protein
BLi03123	COG1360	Flagellar Motor Protein
BLi03124	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BLi03125	COG1609	Transcriptional regulator
BLi03126	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BLi03126	COG1605	Chorismate mutase
BLi03128	COG3118	belongs to the thioredoxin family
BLi03129	COG4980	gas vesicle protein
BLi03130	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BLi03131	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BLi03132	COG1674	ftsk spoiiie
BLi03133	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BLi03134	COG4848	Belongs to the UPF0354 family
BLi03135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLi03137	COG1363	Peptidase, m42
BLi03138	COG5584	Small secreted protein
BLi03139	COG0281	malic enzyme
BLi03140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BLi03141	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BLi03143	COG0510	thiamine kinase activity
BLi03144	COG1523	belongs to the glycosyl hydrolase 13 family
BLi03145	COG1597	lipid kinase activity
BLi03147	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BLi03148	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BLi03151	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BLi03152	COG2252	PERMEase
BLi03153	COG1349	DNA-binding transcription factor activity
BLi03154	COG1187	pseudouridine synthase activity
BLi03155	COG2244	polysaccharide biosynthetic process
BLi03156	COG2081	HI0933 family
BLi03157	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BLi03159	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BLi03160	COG0457	Tetratricopeptide repeat
BLi03162	COG5578	integral membrane protein
BLi03163	COG0673	inositol 2-dehydrogenase activity
BLi03164	COG1653	transport
BLi03165	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BLi03166	COG4209	transmembrane transport
BLi03167	COG2207	Transcriptional regulator
BLi03168	COG1653	transport
BLi03169	COG0395	ABC-type sugar transport system, permease component
BLi03170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BLi03171	COG1073	alpha beta
BLi03173	COG0583	DNA-binding transcription factor activity
BLi03174	COG0346	lactoylglutathione lyase activity
BLi03175	COG0495	leucyl-tRNA aminoacylation
BLi03177	COG2814	Major facilitator Superfamily
BLi03179	COG2433	Pfam Transposase IS66
BLi03181	COG0577	efflux transmembrane transporter activity
BLi03182	COG1136	(ABC) transporter
BLi03184	COG1131	(ABC) transporter
BLi03185	COG1725	Transcriptional regulator
BLi03187	COG1242	4 iron, 4 sulfur cluster binding
BLi03188	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BLi03189	COG1301	dicarboxylic acid transport
BLi03191	COG2267	carboxylic ester hydrolase activity
BLi03192	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BLi03193	COG0671	phosphoesterase, PA-phosphatase related
BLi03194	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BLi03194	COG0438	transferase activity, transferring glycosyl groups
BLi03195	COG0367	asparagine synthase
BLi03196	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BLi03197	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BLi03200	COG1506	peptidase
BLi03201	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BLi03202	COG1116	anion transmembrane transporter activity
BLi03203	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BLi03204	COG0494	nUDIX hydrolase
BLi03206	COG4824	toxin secretion phage lysis holin
BLi03207	COG0783	Belongs to the Dps family
BLi03209	COG1854	S-ribosylhomocysteine lyase activity
BLi03210	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BLi03211	COG0288	reversible hydration of carbon dioxide
BLi03212	COG0523	cobalamin synthesis protein
BLi03213	COG0803	Belongs to the bacterial solute-binding protein 9 family
BLi03214	COG0254	rRNA binding
BLi03215	COG1271	oxidase subunit
BLi03216	COG1294	oxidase, subunit
BLi03218	COG4948	Mandelate Racemase Muconate Lactonizing
BLi03219	COG0318	PFAM AMP-dependent synthetase and ligase
BLi03220	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BLi03221	COG0596	Alpha beta hydrolase
BLi03222	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BLi03223	COG1169	isochorismate synthase
BLi03224	COG1575	Belongs to the MenA family. Type 1 subfamily
BLi03225	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BLi03226	COG0058	SHG alpha-glucan phosphorylase activity
BLi03227	COG0297	glycogen (starch) synthase activity
BLi03228	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BLi03229	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BLi03230	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BLi03256	COG1609	Transcriptional regulator
BLi03258	COG3859	Proton-coupled thiamine transporter YuaJ
BLi03259	COG3764	Sortase (surface protein transpeptidase)
BLi03261	COG0457	Tetratricopeptide repeat
BLi03263	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BLi03264	COG0569	domain protein
BLi03265	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BLi03267	COG2318	DinB family
BLi03269	COG1454	alcohol dehydrogenase
BLi03271	COG1510	regulation of RNA biosynthetic process
BLi03273	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BLi03274	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BLi03285	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
BLi03287	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BLi03288	COG0726	polysaccharide deacetylase
BLi03289	COG1408	metallophosphoesterase
BLi03290	COG1968	undecaprenyl-diphosphatase activity
BLi03291	COG0628	permease
BLi03293	COG0673	inositol 2-dehydrogenase activity
BLi03294	COG0693	protein deglycase activity
BLi03295	COG0840	transmembrane signaling receptor activity
BLi03296	COG0840	transmembrane signaling receptor activity
BLi03297	COG0840	transmembrane signaling receptor activity
BLi03299	COG2070	2-Nitropropane dioxygenase
BLi03300	COG0432	Pfam Uncharacterised protein family UPF0047
BLi03301	COG0366	Alpha amylase catalytic
BLi03304	COG5297	Belongs to the glycosyl hydrolase family 6
BLi03305	COG1253	flavin adenine dinucleotide binding
BLi03306	COG2738	Putative neutral zinc metallopeptidase
BLi03309	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BLi03311	COG2323	membrane
BLi03312	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BLi03314	COG0166	Belongs to the GPI family
BLi03317	COG1979	alcohol dehydrogenase
BLi03318	COG2155	Conserved Protein
BLi03319	COG1098	S1 RNA binding domain
BLi03320	COG0436	Aminotransferase
BLi03321	COG1522	sequence-specific DNA binding
BLi03322	COG2267	carboxylic ester hydrolase activity
BLi03326	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BLi03329	COG5018	Exonuclease
BLi03330	COG2814	Major facilitator Superfamily
BLi03331	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BLi03332	COG3011	Protein conserved in bacteria
BLi03334	COG3290	protein histidine kinase activity
BLi03335	COG4565	transcriptional regulatory protein
BLi03337	COG1183	phosphatidylcholine synthase activity
BLi03338	COG0586	Pfam SNARE associated Golgi protein
BLi03339	COG0688	phosphatidylethanolamine metabolic process
BLi03340	COG2801	Transposase and inactivated derivatives
BLi03342	COG3493	citrate carrier protein
BLi03345	COG2111	Na H antiporter
BLi03345	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BLi03346	COG2111	Na H antiporter
BLi03347	COG1006	Multisubunit Na H antiporter MnhC subunit
BLi03348	COG0651	ATP synthesis coupled electron transport
BLi03349	COG1863	multisubunit Na H antiporter MnhE subunit
BLi03350	COG2212	antiporter activity
BLi03351	COG1320	monovalent cation:proton antiporter activity
BLi03352	COG2050	protein possibly involved in aromatic compounds catabolism
BLi03353	COG2197	response regulator
BLi03355	COG2801	Transposase and inactivated derivatives
BLi03362	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BLi03363	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BLi03364	COG1335	isochorismatase
BLi03365	COG5506	Protein of unknown function (DUF1694)
BLi03368	COG0628	permease
BLi03369	COG1959	2 iron, 2 sulfur cluster binding
BLi03372	COG1418	mRNA catabolic process
BLi03373	COG1028	Short-chain dehydrogenase reductase Sdr
BLi03375	COG1511	domain protein
BLi03376	COG0433	COG0433 Predicted ATPase
BLi03376	COG1674	ftsk spoiiie
BLi03377	COG4499	WXG100 protein secretion system (Wss), protein YukC
BLi03378	COG5417	Belongs to the EsaB family
BLi03379	COG4842	Belongs to the WXG100 family
BLi03380	COG1115	amino acid carrier protein
BLi03381	COG2508	Transcriptional regulator
BLi03381	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BLi03382	COG0686	Belongs to the AlaDH PNT family
BLi03384	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BLi03385	COG1268	BioY protein
BLi03386	COG2056	Na+-H+ antiporter family
BLi03387	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BLi03388	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BLi03389	COG3584	3D domain protein
BLi03392	COG1252	NADH dehydrogenase
BLi03393	COG0492	ferredoxin-NADP+ reductase activity
BLi03397	COG0456	acetyltransferase
BLi03398	COG0316	Belongs to the HesB IscA family
BLi03399	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BLi03400	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BLi03401	COG4844	belongs to the
BLi03402	COG1252	NADH dehydrogenase
BLi03403	COG5646	InterPro IPR014922
BLi03406	COG0457	Tetratricopeptide repeat
BLi03407	COG3479	Phenolic acid decarboxylase
BLi03409	COG4837	Protein of unknown function (DUF1462)
BLi03410	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BLi03411	COG0823	Involved in the tonB-independent uptake of proteins
BLi03411	COG1506	peptidase
BLi03411	COG4946	Tricorn protease homolog
BLi03412	COG0083	homoserine kinase activity
BLi03413	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BLi03414	COG0460	homoserine dehydrogenase
BLi03416	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BLi03417	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BLi03418	COG0647	UMP catabolic process
BLi03419	COG2445	Protein of unknown function DUF86
BLi03420	COG4470	Protein conserved in bacteria
BLi03423	COG0739	heme binding
BLi03425	COG0733	neurotransmitter:sodium symporter activity
BLi03427	COG3377	Domain of unknown function (DUF1805)
BLi03428	COG0737	Belongs to the 5'-nucleotidase family
BLi03429	COG0730	response to heat
BLi03430	COG1801	Protein of unknown function DUF72
BLi03432	COG3226	Transcriptional regulator
BLi03434	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BLi03435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BLi03436	COG2508	Transcriptional regulator
BLi03437	COG2814	Major facilitator Superfamily
BLi03438	COG1288	antiporter activity
BLi03439	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BLi03440	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BLi03441	COG2356	endonuclease I
BLi03443	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BLi03446	COG0457	Tetratricopeptide repeat
BLi03447	COG0719	Fe-S assembly protein
BLi03448	COG0822	iron-sulfur transferase activity
BLi03449	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BLi03450	COG0719	Fe-S assembly protein
BLi03451	COG0396	ATPase activity
BLi03454	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BLi03455	COG1464	Belongs to the NlpA lipoprotein family
BLi03456	COG2011	ABC-type metal ion transport system permease component
BLi03457	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BLi03459	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLi03460	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BLi03462	COG0509	glycine decarboxylation via glycine cleavage system
BLi03463	COG1393	Belongs to the ArsC family
BLi03464	COG1960	acyl-CoA dehydrogenase activity
BLi03465	COG0183	Belongs to the thiolase family
BLi03466	COG1250	3-hydroxyacyl-CoA dehydrogenase
BLi03466	COG1024	Enoyl-CoA hydratase
BLi03469	COG5577	PFAM Coat F domain
BLi03472	COG1120	ATPase activity
BLi03473	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLi03474	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLi03475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BLi03478	COG1686	Belongs to the peptidase S11 family
BLi03479	COG1028	Short-chain dehydrogenase reductase Sdr
BLi03480	COG0783	Belongs to the Dps family
BLi03481	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BLi03482	COG0745	RESPONSE REGULATOR receiver
BLi03483	COG2205	protein histidine kinase activity
BLi03483	COG2770	Histidine kinase
BLi03485	COG1309	transcriptional regulator
BLi03486	COG0114	fumarate hydratase activity
BLi03488	COG0697	spore germination
BLi03489	COG0814	amino acid
BLi03492	COG2197	response regulator
BLi03493	COG4585	Histidine kinase
BLi03494	COG4758	membrane
BLi03496	COG1842	Phage shock protein A
BLi03497	COG4758	membrane
BLi03498	COG4677	pectinesterase activity
BLi03499	COG2096	Adenosyltransferase
BLi03500	COG1028	Short-chain dehydrogenase reductase Sdr
BLi03501	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BLi03502	COG1454	alcohol dehydrogenase
BLi03503	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BLi03504	COG1120	ATPase activity
BLi03505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLi03506	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BLi03507	COG1802	Transcriptional regulator
BLi03508	COG1028	Short-chain dehydrogenase reductase Sdr
BLi03509	COG2258	MOSC domain
BLi03510	COG0583	DNA-binding transcription factor activity
BLi03512	COG2721	sulfolactate sulfo-lyase activity
BLi03513	COG0246	Mannitol dehydrogenase
BLi03514	COG1609	Transcriptional regulator
BLi03515	COG2211	Major facilitator Superfamily
BLi03516	COG1904	glucuronate isomerase
BLi03517	COG2205	protein histidine kinase activity
BLi03518	COG0745	RESPONSE REGULATOR receiver
BLi03519	COG1120	ATPase activity
BLi03520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLi03521	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLi03522	COG0531	amino acid
BLi03525	COG1988	membrane-bound metal-dependent
BLi03526	COG1368	sulfuric ester hydrolase activity
BLi03527	COG2814	Major facilitator Superfamily
BLi03528	COG0656	L-ascorbic acid biosynthetic process
BLi03529	COG1940	carbohydrate kinase activity
BLi03531	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BLi03533	COG3973	AAA domain
BLi03534	COG2860	membrane
BLi03535	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BLi03535	COG0456	acetyltransferase
BLi03536	COG0456	acetyltransferase
BLi03537	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BLi03538	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BLi03539	COG2217	Heavy metal translocating P-type atpase
BLi03540	COG1653	transport
BLi03541	COG1175	transmembrane transport
BLi03542	COG0395	ABC-type sugar transport system, permease component
BLi03543	COG1501	Belongs to the glycosyl hydrolase 31 family
BLi03544	COG1472	Belongs to the glycosyl hydrolase 3 family
BLi03545	COG1121	(ABC) transporter
BLi03546	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BLi03547	COG0803	Belongs to the bacterial solute-binding protein 9 family
BLi03550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLi03550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BLi03550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BLi03553	COG2217	Heavy metal translocating P-type atpase
BLi03554	COG2608	mercury ion transmembrane transporter activity
BLi03555	COG1937	Protein conserved in bacteria
BLi03556	COG0693	protein deglycase activity
BLi03557	COG1349	DNA-binding transcription factor activity
BLi03558	COG1070	Carbohydrate kinase
BLi03559	COG4952	isomerase
BLi03561	COG1028	Short-chain dehydrogenase reductase Sdr
BLi03561	COG3347	Dehydrogenase
BLi03562	COG2814	Major facilitator Superfamily
BLi03565	COG2814	Major facilitator Superfamily
BLi03567	COG2124	cytochrome p450
BLi03569	COG1846	Transcriptional regulator
BLi03572	COG0673	inositol 2-dehydrogenase activity
BLi03573	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BLi03577	COG1191	sigma factor activity
BLi03580	COG2140	Oxalate decarboxylase
BLi03590	COG2801	Transposase and inactivated derivatives
BLi03592	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BLi03596	COG5444	nuclease activity
BLi03604	COG1705	Flagellar rod assembly protein muramidase FlgJ
BLi03606	COG5280	Phage tail tape measure protein TP901
BLi03606	COG3953	SLT domain
BLi03618	COG4626	Terminase
BLi03618	COG1802	Transcriptional regulator
BLi03640	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BLi03641	COG0557	exoribonuclease II activity
BLi03642	COG1647	Serine aminopeptidase, S33
BLi03643	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BLi03644	COG2002	toxin-antitoxin pair type II binding
BLi03645	COG1476	TRANSCRIPTIONal
BLi03646	COG1396	sequence-specific DNA binding
BLi03647	COG1396	sequence-specific DNA binding
BLi03648	COG1174	glycine betaine transport
BLi03649	COG1732	Glycine betaine
BLi03650	COG1174	glycine betaine transport
BLi03651	COG1125	glycine betaine transport
BLi03651	COG0517	IMP dehydrogenase activity
BLi03652	COG1510	regulation of RNA biosynthetic process
BLi03653	COG2095	MarC family integral membrane protein
BLi03654	COG3064	Membrane
BLi03657	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BLi03661	COG0148	phosphopyruvate hydratase activity
BLi03662	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BLi03663	COG0149	triose-phosphate isomerase activity
BLi03664	COG0126	phosphoglycerate kinase activity
BLi03665	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BLi03666	COG2390	Transcriptional regulator
BLi03668	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BLi03669	COG1113	amino acid transport
BLi03673	COG1556	Lactate utilization protein
BLi03674	COG1139	Iron-sulfur cluster binding protein
BLi03675	COG0247	lactate metabolic process
BLi03676	COG2186	Transcriptional regulator
BLi03677	COG1620	l-lactate permease
BLi03678	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BLi03680	COG5039	Polysaccharide pyruvyl transferase
BLi03681	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BLi03682	COG0110	maltose O-acetyltransferase activity
BLi03683	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BLi03684	COG2244	polysaccharide biosynthetic process
BLi03685	COG1216	Glycosyl transferase, family 2
BLi03686	COG5039	Polysaccharide pyruvyl transferase
BLi03687	COG1216	Glycosyl transferase, family 2
BLi03689	COG0438	transferase activity, transferring glycosyl groups
BLi03690	COG1215	transferase activity, transferring glycosyl groups
BLi03691	COG0438	transferase activity, transferring glycosyl groups
BLi03692	COG1086	Polysaccharide biosynthesis protein
BLi03693	COG0489	protein tyrosine kinase activity
BLi03694	COG3944	biosynthesis protein
BLi03695	COG1396	sequence-specific DNA binding
BLi03696	COG2249	NAD(P)H dehydrogenase (quinone) activity
BLi03697	COG2271	Major facilitator Superfamily
BLi03699	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BLi03702	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BLi03704	COG1733	regulation of RNA biosynthetic process
BLi03705	COG1902	pentaerythritol trinitrate reductase activity
BLi03706	COG1621	beta-fructofuranosidase activity
BLi03707	COG1621	beta-fructofuranosidase activity
BLi03710	COG0740	serine-type endopeptidase activity
BLi03711	COG1611	Belongs to the LOG family
BLi03712	COG1694	Mazg nucleotide pyrophosphohydrolase
BLi03713	COG1078	dGTPase activity
BLi03714	COG0659	secondary active sulfate transmembrane transporter activity
BLi03715	COG0288	reversible hydration of carbon dioxide
BLi03716	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BLi03717	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BLi03718	COG0640	Transcriptional regulator
BLi03720	COG2732	(Barnase) inhibitor
BLi03721	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BLi03722	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLi03723	COG1481	regulation of sporulation
BLi03724	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BLi03725	COG1660	Displays ATPase and GTPase activities
BLi03726	COG1051	belongs to the nudix hydrolase family
BLi03728	COG0492	ferredoxin-NADP+ reductase activity
BLi03729	COG0457	Tetratricopeptide repeat
BLi03730	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BLi03731	COG0140	phosphoribosyl-ATP diphosphatase activity
BLi03731	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BLi03732	COG0107	imidazoleglycerol-phosphate synthase activity
BLi03733	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BLi03734	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BLi03735	COG0131	Imidazoleglycerol-phosphate dehydratase
BLi03736	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BLi03737	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BLi03738	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BLi03739	COG4990	cell redox homeostasis
BLi03741	COG5297	Belongs to the glycosyl hydrolase family 6
BLi03742	COG0110	maltose O-acetyltransferase activity
BLi03743	COG0546	phosphoglycolate phosphatase activity
BLi03744	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BLi03745	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BLi03746	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BLi03747	COG1846	Transcriptional regulator
BLi03748	COG2814	Major facilitator Superfamily
BLi03749	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BLi03750	COG1950	PFAM Membrane protein of
BLi03751	COG1983	PspC domain protein
BLi03752	COG3595	metallopeptidase activity
BLi03758	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BLi03759	COG0556	nucleotide-excision repair
BLi03760	COG4897	Protein conserved in bacteria
BLi03762	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BLi03765	COG3409	Peptidoglycan-binding domain 1 protein
BLi03765	COG0793	Belongs to the peptidase S41A family
BLi03766	COG0473	3-isopropylmalate dehydrogenase activity
BLi03767	COG0791	NLP P60 protein
BLi03767	COG3883	PFAM NLP P60 protein
BLi03768	COG2177	Part of the ABC transporter FtsEX involved in
BLi03769	COG2884	Cell division ATP-binding protein ftsE
BLi03770	COG2010	Cytochrome c
BLi03771	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BLi03772	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BLi03773	COG0653	protein targeting
BLi03774	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BLi03777	COG1516	flagellar protein fliS
BLi03778	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BLi03779	COG1334	flagellar protein FlaG
BLi03780	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BLi03781	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BLi03782	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BLi03784	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BLi03785	COG4786	Flagellar basal body rod
BLi03785	COG1256	bacterial-type flagellum assembly
BLi03786	COG3418	PFAM FlgN family protein
BLi03787	COG2747	anti-sigma28 factor FlgM
BLi03789	COG1040	competence protein
BLi03791	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BLi03792	COG1307	EDD domain protein, DegV family
BLi03793	COG2197	response regulator
BLi03794	COG4585	Histidine kinase
BLi03795	COG1739	Uncharacterized protein family UPF0029
BLi03796	COG1316	TRANSCRIPTIONal
BLi03798	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BLi03799	COG0438	transferase activity, transferring glycosyl groups
BLi03800	COG1215	transferase activity, transferring glycosyl groups
BLi03801	COG3206	protein involved in exopolysaccharide biosynthesis
BLi03802	COG3307	-O-antigen
BLi03803	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BLi03804	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BLi03805	COG0438	transferase activity, transferring glycosyl groups
BLi03805	COG0297	glycogen (starch) synthase activity
BLi03806	COG2244	polysaccharide biosynthetic process
BLi03808	COG2247	cell wall binding repeat
BLi03808	COG0860	N-Acetylmuramoyl-L-alanine amidase
BLi03809	COG2247	cell wall binding repeat
BLi03809	COG2385	sporulation resulting in formation of a cellular spore
BLi03811	COG1316	TRANSCRIPTIONal
BLi03812	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BLi03813	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BLi03814	COG1134	teichoic acid transport
BLi03815	COG1682	transport, permease protein
BLi03816	COG0463	Glycosyl transferase, family 2
BLi03816	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BLi03817	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BLi03818	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BLi03819	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BLi03820	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BLi03821	COG4193	domain, Protein
BLi03822	COG1482	cell wall glycoprotein biosynthetic process
BLi03826	COG0800	Aldolase
BLi03827	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BLi03828	COG1609	Transcriptional regulator
BLi03829	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BLi03830	COG1028	Short-chain dehydrogenase reductase Sdr
BLi03831	COG1063	alcohol dehydrogenase
BLi03832	COG2814	Major facilitator Superfamily
BLi03833	COG1316	TRANSCRIPTIONal
BLi03834	COG0561	phosphatase activity
BLi03835	COG0791	NLP P60 protein
BLi03837	COG2843	Capsule synthesis protein
BLi03839	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BLi03840	COG1609	Transcriptional regulator
BLi03841	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BLi03842	COG1869	D-ribose catabolic process
BLi03843	COG1129	ABC transporter
BLi03844	COG1172	Belongs to the binding-protein-dependent transport system permease family
BLi03845	COG1879	ABC-type sugar transport system periplasmic component
BLi03847	COG3527	Alpha-acetolactate decarboxylase
BLi03848	COG0028	Belongs to the TPP enzyme family
BLi03849	COG0583	DNA-binding transcription factor activity
BLi03850	COG0405	Gamma-glutamyltransferase
BLi03851	COG1522	sequence-specific DNA binding
BLi03852	COG2059	Chromate
BLi03853	COG2059	Chromate
BLi03854	COG4464	protein tyrosine phosphatase activity
BLi03855	COG3944	biosynthesis protein
BLi03857	COG4715	Zinc finger, swim domain protein
BLi03858	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BLi03860	COG0561	phosphatase activity
BLi03861	COG1349	DNA-binding transcription factor activity
BLi03863	COG1028	Short-chain dehydrogenase reductase Sdr
BLi03865	COG3732	PTS system glucitol sorbitol-specific
BLi03869	COG0629	single-stranded DNA binding
BLi03872	COG1970	mechanosensitive ion channel activity
BLi03873	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BLi03874	COG4786	Flagellar basal body rod
BLi03875	COG4786	Flagellar basal body rod
BLi03876	COG1077	Cell shape determining protein MreB Mrl
BLi03878	COG1609	Transcriptional regulator
BLi03879	COG1846	Transcriptional regulator
BLi03880	COG2814	Major facilitator Superfamily
BLi03881	COG0671	phosphoesterase, PA-phosphatase related
BLi03882	COG1227	inorganic diphosphatase activity
BLi03883	COG3546	catalase activity
BLi03884	COG3361	conserved protein (COG2071)
BLi03885	COG0517	IMP dehydrogenase activity
BLi03886	COG0598	Magnesium transport protein CorA
BLi03887	COG1253	flavin adenine dinucleotide binding
BLi03888	COG0004	ammonium transporteR
BLi03889	COG0347	Belongs to the P(II) protein family
BLi03890	COG0740	serine-type endopeptidase activity
BLi03892	COG0739	heme binding
BLi03893	COG1247	-acetyltransferase
BLi03895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BLi03896	COG0477	Major facilitator Superfamily
BLi03897	COG3251	PFAM MbtH domain protein
BLi03898	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BLi03899	COG1535	isochorismatase
BLi03899	COG3433	isochorismatase activity
BLi03900	COG1021	2,3-dihydroxybenzoate-AMP ligase
BLi03901	COG1169	isochorismate synthase
BLi03902	COG1028	Short-chain dehydrogenase reductase Sdr
BLi03903	COG2819	hydrolase of the alpha beta superfamily
BLi03904	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLi03905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLi03906	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BLi03907	COG2207	Transcriptional regulator
BLi03907	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BLi03909	COG2801	Transposase and inactivated derivatives
BLi03911	COG2910	NAD(P)H-binding
BLi03912	COG1959	2 iron, 2 sulfur cluster binding
BLi03914	COG1994	Peptidase M50
BLi03915	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BLi03916	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BLi03918	COG3383	formate dehydrogenase (NAD+) activity
BLi03919	COG2304	oxidoreductase activity
BLi03920	COG2304	oxidoreductase activity
BLi03921	COG2385	sporulation resulting in formation of a cellular spore
BLi03922	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BLi03924	COG4836	Membrane
BLi03925	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BLi03926	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BLi03927	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BLi03928	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BLi03929	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BLi03930	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BLi03931	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BLi03934	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BLi03935	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BLi03936	COG4475	Protein of unknown function (DUF436)
BLi03937	COG0698	ribose 5-phosphate isomerase
BLi03938	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BLi03939	COG1971	Probably functions as a manganese efflux pump
BLi03940	COG0009	L-threonylcarbamoyladenylate synthase
BLi03941	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BLi03943	COG0738	Major facilitator superfamily
BLi03944	COG0673	inositol 2-dehydrogenase activity
BLi03945	COG0561	phosphatase activity
BLi03946	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BLi03947	COG1609	Transcriptional regulator
BLi03948	COG2890	protein-(glutamine-N5) methyltransferase activity
BLi03949	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BLi03950	COG0346	lactoylglutathione lyase activity
BLi03951	COG0789	Transcriptional regulator
BLi03952	COG0679	Auxin Efflux Carrier
BLi03953	COG0281	malic enzyme
BLi03954	COG1435	thymidine kinase activity
BLi03955	COG0254	rRNA binding
BLi03956	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BLi03957	COG1494	fructose-1,6-bisphosphatase
BLi03958	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BLi03959	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BLi03960	COG0191	fructose-bisphosphate aldolase activity
BLi03961	COG2204	response regulator
BLi03962	COG4821	SIS domain
BLi03963	COG0504	CTP synthase activity
BLi03964	COG3343	RNA polymerase activity
BLi03965	COG1960	acyl-CoA dehydrogenase activity
BLi03966	COG1960	acyl-CoA dehydrogenase activity
BLi03967	COG1250	3-hydroxyacyl-CoA dehydrogenase
BLi03968	COG0183	Belongs to the thiolase family
BLi03969	COG0247	lactate metabolic process
BLi03969	COG2181	nitrate reductase activity
BLi03970	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BLi03971	COG0018	arginyl-trna synthetase
BLi03972	COG4506	Protein conserved in bacteria
BLi03973	COG0010	Belongs to the arginase family
BLi03974	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BLi03977	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BLi03979	COG1994	Peptidase M50
BLi03980	COG1942	4-Oxalocrotonate Tautomerase
BLi03982	COG3465	dGTPase activity
BLi03983	COG1078	dGTPase activity
BLi03984	COG4844	belongs to the
BLi03990	COG2814	Major facilitator Superfamily
BLi03995	COG1414	Transcriptional regulator
BLi03997	COG0280	phosphate acetyltransferase
BLi04001	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BLi04005	COG1131	(ABC) transporter
BLi04008	COG2363	Small membrane protein
BLi04009	COG2233	PERMEase
BLi04011	COG1012	belongs to the aldehyde dehydrogenase family
BLi04012	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BLi04013	COG1216	Glycosyl transferase, family 2
BLi04014	COG0351	phosphomethylpyrimidine kinase
BLi04016	COG1621	beta-fructofuranosidase activity
BLi04017	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLi04017	COG1263	PTS System
BLi04018	COG3711	transcriptional antiterminator
BLi04019	COG1404	Belongs to the peptidase S8 family
BLi04021	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BLi04022	COG0778	Nitroreductase
BLi04023	COG1473	amidohydrolase
BLi04024	COG0772	Belongs to the SEDS family
BLi04025	COG0772	Belongs to the SEDS family
BLi04030	COG0456	acetyltransferase
BLi04037	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BLi04039	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BLi04040	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BLi04041	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BLi04045	COG3162	membrane
BLi04046	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BLi04047	COG1070	Carbohydrate kinase
BLi04048	COG2115	Belongs to the xylose isomerase family
BLi04051	COG0352	thiamine-phosphate diphosphorylase activity
BLi04052	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BLi04057	COG1380	Effector of murein hydrolase LrgA
BLi04058	COG1346	cytolysis
BLi04059	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BLi04060	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BLi04061	COG0346	lactoylglutathione lyase activity
BLi04064	COG1442	glycosyl transferase family 8
BLi04065	COG4585	Histidine kinase
BLi04066	COG2197	response regulator
BLi04067	COG2409	Drug exporters of the RND superfamily
BLi04068	COG5522	Integral membrane protein (intg_mem_TP0381)
BLi04069	COG2271	Major facilitator Superfamily
BLi04070	COG4948	Mandelate Racemase Muconate Lactonizing
BLi04071	COG0800	Aldolase
BLi04072	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BLi04074	COG2234	aminopeptidase activity
BLi04075	COG0477	Major facilitator Superfamily
BLi04078	COG2357	RelA SpoT domain protein
BLi04080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BLi04081	COG1696	Membrane protein involved in D-alanine export
BLi04082	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BLi04083	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BLi04084	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BLi04085	COG2814	Major facilitator Superfamily
BLi04086	COG1486	melibiose metabolic process
BLi04087	COG1447	Phosphotransferase system cellobiose-specific component IIA
BLi04088	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BLi04089	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BLi04090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLi04090	COG3711	transcriptional antiterminator
BLi04092	COG2094	Belongs to the DNA glycosylase MPG family
BLi04094	COG0372	Belongs to the citrate synthase family
BLi04095	COG2079	MmgE PrpD family protein
BLi04096	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BLi04099	COG1132	(ABC) transporter
BLi04100	COG2755	lipolytic protein G-D-S-L family
BLi04103	COG2814	Major facilitator Superfamily
BLi04104	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BLi04105	COG1131	(ABC) transporter
BLi04109	COG1595	DNA-templated transcription, initiation
BLi04110	COG2814	Major facilitator Superfamily
BLi04111	COG0753	catalase activity
BLi04113	COG0753	catalase activity
BLi04114	COG0735	belongs to the Fur family
BLi04116	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BLi04117	COG1131	(ABC) transporter
BLi04120	COG1131	(ABC) transporter
BLi04129	COG3866	Pectate lyase
BLi04130	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BLi04131	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BLi04132	COG4988	ABC transporter
BLi04133	COG1294	oxidase, subunit
BLi04134	COG1271	oxidase subunit
BLi04135	COG2116	formate transmembrane transporter activity
BLi04137	COG0281	malic enzyme
BLi04138	COG1757	Na H antiporter
BLi04139	COG1027	Aspartate ammonia-lyase
BLi04140	COG0252	asparaginase activity
BLi04141	COG1396	sequence-specific DNA binding
BLi04142	COG2706	6-phosphogluconolactonase activity
BLi04145	COG2205	protein histidine kinase activity
BLi04146	COG1136	(ABC) transporter
BLi04147	COG0577	efflux transmembrane transporter activity
BLi04148	COG5294	Protein conserved in bacteria
BLi04151	COG0726	polysaccharide deacetylase
BLi04154	COG1215	transferase activity, transferring glycosyl groups
BLi04155	COG3493	citrate carrier protein
BLi04156	COG0584	glycerophosphoryl diester phosphodiesterase
BLi04159	COG1368	sulfuric ester hydrolase activity
BLi04161	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BLi04163	COG2235	arginine
BLi04164	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BLi04166	COG0549	Belongs to the carbamate kinase family
BLi04168	COG2723	6-phospho-beta-galactosidase activity
BLi04169	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BLi04171	COG1595	DNA-templated transcription, initiation
BLi04176	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BLi04177	COG2195	Cleaves the N-terminal amino acid of tripeptides
BLi04178	COG1621	beta-fructofuranosidase activity
BLi04179	COG2223	nitrite transmembrane transporter activity
BLi04180	COG0395	ABC-type sugar transport system, permease component
BLi04181	COG1175	transmembrane transport
BLi04183	COG1609	Transcriptional regulator
BLi04187	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BLi04188	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BLi04189	COG0463	Glycosyl transferase, family 2
BLi04190	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BLi04195	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BLi04199	COG2723	6-phospho-beta-galactosidase activity
BLi04200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLi04200	COG1263	PTS System
BLi04200	COG2190	(PTS) system
BLi04201	COG3711	transcriptional antiterminator
BLi04202	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BLi04203	COG1122	ATPase activity
BLi04204	COG4721	ABC-type cobalt transport system, permease component
BLi04205	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BLi04207	COG2224	Isocitrate lyase
BLi04208	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BLi04209	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BLi04210	COG0577	efflux transmembrane transporter activity
BLi04211	COG1136	(ABC) transporter
BLi04212	COG2205	protein histidine kinase activity
BLi04213	COG0745	RESPONSE REGULATOR receiver
BLi04214	COG2723	6-phospho-beta-galactosidase activity
BLi04215	COG1263	PTS System
BLi04215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLi04215	COG2190	(PTS) system
BLi04217	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BLi04220	COG3507	Belongs to the glycosyl hydrolase 43 family
BLi04221	COG0513	Belongs to the DEAD box helicase family
BLi04227	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BLi04228	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BLi04229	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BLi04230	COG2390	Transcriptional regulator
BLi04232	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BLi04233	COG3706	GGDEF domain
BLi04234	COG5298	Protein conserved in bacteria
BLi04235	COG1215	transferase activity, transferring glycosyl groups
BLi04237	COG3977	Valine--pyruvate aminotransferase
BLi04240	COG1181	Belongs to the D-alanine--D-alanine ligase family
BLi04242	COG0191	fructose-bisphosphate aldolase activity
BLi04243	COG1082	Xylose isomerase domain protein TIM barrel
BLi04244	COG1082	Xylose isomerase domain protein TIM barrel
BLi04245	COG0673	inositol 2-dehydrogenase activity
BLi04246	COG2814	Major facilitator Superfamily
BLi04247	COG1082	Xylose isomerase domain protein TIM barrel
BLi04248	COG3962	Belongs to the TPP enzyme family
BLi04249	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BLi04250	COG3718	enzyme involved in inositol metabolism
BLi04251	COG1012	belongs to the aldehyde dehydrogenase family
BLi04252	COG1349	DNA-binding transcription factor activity
BLi04253	COG0667	Aldo Keto reductase
BLi04254	COG0584	glycerophosphoryl diester phosphodiesterase
BLi04255	COG2271	Major facilitator Superfamily
BLi04256	COG0326	Molecular chaperone. Has ATPase activity
BLi04257	COG0488	(ABC) transporter
BLi04258	COG0561	phosphatase activity
BLi04262	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BLi04267	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
BLi04268	COG0577	efflux transmembrane transporter activity
BLi04269	COG1136	(ABC) transporter
BLi04270	COG2205	protein histidine kinase activity
BLi04271	COG0745	RESPONSE REGULATOR receiver
BLi04273	COG0840	transmembrane signaling receptor activity
BLi04273	COG5278	phosphoserine phosphatase activity
BLi04274	COG1115	amino acid carrier protein
BLi04275	COG0686	Belongs to the AlaDH PNT family
BLi04276	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BLi04277	COG1874	Beta-galactosidase
BLi04278	COG3833	ABC-type maltose transport systems, permease component
BLi04279	COG1175	transmembrane transport
BLi04280	COG2182	Extracellular solute-binding protein
BLi04281	COG1609	Transcriptional regulator
BLi04283	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BLi04284	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BLi04285	COG1940	carbohydrate kinase activity
BLi04290	COG1012	belongs to the aldehyde dehydrogenase family
BLi04290	COG1454	alcohol dehydrogenase
BLi04291	COG0450	alkyl hydroperoxide reductase
BLi04292	COG3634	alkyl hydroperoxide reductase activity
BLi04298	COG1131	(ABC) transporter
BLi04302	COG4585	Histidine kinase
BLi04303	COG4585	Histidine kinase
BLi04304	COG2197	response regulator
BLi04315	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BLi04323	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BLi04324	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BLi04327	COG0456	acetyltransferase
BLi04330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BLi04331	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BLi04332	COG4853	Protein conserved in bacteria
BLi04333	COG4863	YycH protein
BLi04334	COG5002	protein histidine kinase activity
BLi04335	COG0745	RESPONSE REGULATOR receiver
BLi04340	COG1051	belongs to the nudix hydrolase family
BLi04341	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BLi04343	COG0305	Participates in initiation and elongation during chromosome replication
BLi04346	COG3093	addiction module antidote protein HigA
BLi04347	COG2807	transmembrane transport
BLi04348	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BLi04349	COG0363	glucosamine-6-phosphate deaminase activity
BLi04351	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BLi04352	COG1263	PTS System
BLi04352	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLi04353	COG0359	binds to the 23S rRNA
BLi04354	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BLi04355	COG4241	membrane
BLi04357	COG5577	PFAM Coat F domain
BLi04358	COG0589	response to stress
BLi04359	COG0659	secondary active sulfate transmembrane transporter activity
BLi04360	COG2271	Major facilitator Superfamily
BLi04361	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BLi04362	COG0629	single-stranded DNA binding
BLi04363	COG0360	Binds together with S18 to 16S ribosomal RNA
BLi04364	COG0012	GTP binding
BLi04365	COG4481	Protein conserved in bacteria
BLi04366	COG3949	Membrane
BLi04368	COG1475	DNA binding
BLi04369	COG1192	Involved in chromosome partitioning
BLi04370	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BLi04372	COG1475	DNA binding
BLi04373	COG0357	Ribosomal RNA small subunit methyltransferase G
BLi04374	COG0445	tRNA wobble uridine modification
BLi04375	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BLi04376	COG1847	R3H domain protein
BLi04377	COG0706	membrane insertase activity
BLi04378	COG0594	ribonuclease P activity
BLi04379	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BLi05000	COG1929	Belongs to the glycerate kinase type-1 family
BLi05002	COG1331	Highly conserved protein containing a thioredoxin domain
BLi05003	COG1115	amino acid carrier protein
BLi05013	COG0861	Integral membrane protein TerC family