locus-tag	class	description
JAV55_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JAV55_00010	COG0592	DNA-directed DNA polymerase activity
JAV55_00015	COG2501	S4 domain
JAV55_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JAV55_00030	COG0187	DNA topoisomerase II activity
JAV55_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JAV55_00070	COG0516	GMP reductase activity
JAV55_00070	COG0517	IMP dehydrogenase activity
JAV55_00075	COG1686	Belongs to the peptidase S11 family
JAV55_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JAV55_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JAV55_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JAV55_00095	COG1929	Belongs to the glycerate kinase type-1 family
JAV55_00100	COG2610	gluconate transmembrane transporter activity
JAV55_00105	COG3835	regulator
JAV55_00120	COG1428	Deoxynucleoside kinase
JAV55_00125	COG1428	Deoxynucleoside kinase
JAV55_00130	COG3858	chitin binding
JAV55_00130	COG1388	LysM domain
JAV55_00135	COG1335	isochorismatase
JAV55_00140	COG0590	tRNA wobble adenosine to inosine editing
JAV55_00150	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JAV55_00155	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JAV55_00160	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JAV55_00205	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
JAV55_00210	COG3853	Toxic anion resistance protein (TelA)
JAV55_00215	COG1982	Orn Lys Arg decarboxylase major
JAV55_00220	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JAV55_00225	COG3870	Protein conserved in bacteria
JAV55_00230	COG1728	Protein conserved in bacteria
JAV55_00235	COG0470	DNA polymerase III
JAV55_00240	COG1774	PSP1 C-terminal conserved region
JAV55_00245	COG4467	Involved in initiation control of chromosome replication
JAV55_00250	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JAV55_00255	COG2827	Endonuclease containing a URI domain
JAV55_00260	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JAV55_00265	COG2002	toxin-antitoxin pair type II binding
JAV55_00270	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JAV55_00270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JAV55_00275	COG0084	hydrolase, TatD family'
JAV55_00280	COG3584	3D domain protein
JAV55_00280	COG3583	domain protein
JAV55_00285	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JAV55_00290	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JAV55_00300	COG4466	Protein conserved in bacteria
JAV55_00310	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JAV55_00315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JAV55_00320	COG0251	oxidation-reduction process
JAV55_00325	COG2088	sporulation resulting in formation of a cellular spore
JAV55_00330	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JAV55_00335	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JAV55_00340	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JAV55_00345	COG0193	aminoacyl-tRNA hydrolase activity
JAV55_00355	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JAV55_00360	COG2002	toxin-antitoxin pair type II binding
JAV55_00365	COG2244	polysaccharide biosynthetic process
JAV55_00370	COG3956	TIGRFAM MazG family protein
JAV55_00375	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JAV55_00390	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
JAV55_00395	COG1098	S1 RNA binding domain
JAV55_00410	COG2208	phosphoserine phosphatase activity
JAV55_00415	COG2304	oxidoreductase activity
JAV55_00420	COG0515	serine threonine protein kinase
JAV55_00425	COG0037	tRNA processing
JAV55_00430	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JAV55_00435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JAV55_00440	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JAV55_00445	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JAV55_00450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JAV55_00455	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JAV55_00460	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JAV55_00465	COG0512	Glutamine amidotransferase of anthranilate synthase
JAV55_00470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JAV55_00475	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JAV55_00480	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JAV55_00485	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JAV55_00490	COG1396	sequence-specific DNA binding
JAV55_00495	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JAV55_00500	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JAV55_00580	COG4463	regulation of RNA biosynthetic process
JAV55_00585	COG3880	PFAM UvrB UvrC protein
JAV55_00590	COG3869	Catalyzes the specific phosphorylation of arginine residues in
JAV55_00595	COG0542	response to heat
JAV55_00600	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JAV55_00605	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
JAV55_00610	COG4956	integral membrane protein (PIN domain superfamily)
JAV55_00615	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JAV55_00620	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JAV55_00625	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JAV55_00630	COG1045	serine acetyltransferase
JAV55_00635	COG0215	cysteine-tRNA ligase activity
JAV55_00640	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JAV55_00645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JAV55_00650	COG3688	RNA-binding protein containing a PIN domain
JAV55_00660	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JAV55_00670	COG0250	Participates in transcription elongation, termination and antitermination
JAV55_00675	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JAV55_00680	COG0081	regulation of translation
JAV55_00685	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JAV55_00690	COG0222	ribosome binding
JAV55_00695	COG2813	Specifically methylates the guanine in position
JAV55_00700	COG0085	RNA polymerase activity
JAV55_00705	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JAV55_00710	COG1358	cellular component organization or biogenesis
JAV55_00715	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JAV55_00720	COG0049	tRNA binding
JAV55_00725	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JAV55_00730	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JAV55_00740	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JAV55_00745	COG0088	Forms part of the polypeptide exit tunnel
JAV55_00750	COG0089	rRNA binding
JAV55_00755	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JAV55_00760	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JAV55_00765	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JAV55_00770	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JAV55_00775	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JAV55_00780	COG0255	Belongs to the universal ribosomal protein uL29 family
JAV55_00785	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JAV55_00790	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JAV55_00795	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JAV55_00800	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JAV55_00805	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JAV55_00810	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JAV55_00815	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JAV55_00820	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JAV55_00825	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JAV55_00830	COG1841	ribosomal large subunit assembly
JAV55_00835	COG0200	Binds to the 23S rRNA
JAV55_00840	COG0201	protein transport
JAV55_00845	COG0563	adenylate kinase activity
JAV55_00850	COG0024	Methionine aminopeptidase
JAV55_00855	COG2163	COG2163 Ribosomal protein L14E L6E L27E
JAV55_00860	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JAV55_00865	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JAV55_00870	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JAV55_00875	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JAV55_00880	COG0202	RNA polymerase activity
JAV55_00885	COG0203	ribosomal protein L17
JAV55_00890	COG1122	ATPase activity
JAV55_00895	COG1122	ATPase activity
JAV55_00900	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JAV55_00905	COG0101	tRNA pseudouridine synthase activity
JAV55_00910	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JAV55_00915	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JAV55_00920	COG2318	DinB family
JAV55_00930	COG0860	N-Acetylmuramoyl-L-alanine amidase
JAV55_00935	COG0489	protein tyrosine kinase activity
JAV55_00945	COG2194	sulfuric ester hydrolase activity
JAV55_00950	COG0726	polysaccharide deacetylase
JAV55_00980	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JAV55_00990	COG0385	Bile acid
JAV55_01005	COG3876	Protein conserved in bacteria
JAV55_01010	COG1472	Belongs to the glycosyl hydrolase 3 family
JAV55_01015	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JAV55_01020	COG1263	PTS System
JAV55_01020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JAV55_01025	COG1737	Transcriptional regulator
JAV55_01030	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JAV55_01035	COG1683	Conserved Protein
JAV55_01070	COG1595	DNA-templated transcription, initiation
JAV55_01075	COG5662	AntiSigma factor
JAV55_01080	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JAV55_01085	COG4856	YbbR-like protein
JAV55_01090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JAV55_01095	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JAV55_01115	COG1725	Transcriptional regulator
JAV55_01120	COG0640	Transcriptional regulator
JAV55_01125	COG2814	Major facilitator Superfamily
JAV55_01135	COG1132	(ABC) transporter
JAV55_01140	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JAV55_01165	COG1011	Hydrolase
JAV55_01170	COG1113	amino acid transport
JAV55_01175	COG2851	Citrate transporter
JAV55_01180	COG3181	Tripartite tricarboxylate transporter family receptor
JAV55_01185	COG4565	transcriptional regulatory protein
JAV55_01190	COG3290	protein histidine kinase activity
JAV55_01205	COG2211	Major facilitator Superfamily
JAV55_01225	COG1331	Highly conserved protein containing a thioredoxin domain
JAV55_01230	COG3677	Transposase
JAV55_01265	COG1331	Highly conserved protein containing a thioredoxin domain
JAV55_01270	COG0477	Major facilitator Superfamily
JAV55_01290	COG1283	sodium-dependent phosphate transmembrane transporter activity
JAV55_01295	COG4682	membrane
JAV55_01320	COG0697	spore germination
JAV55_01325	COG1917	Cupin 2, conserved barrel domain protein
JAV55_01325	COG2207	Transcriptional regulator
JAV55_01345	COG0371	Dehydrogenase
JAV55_01350	COG0840	transmembrane signaling receptor activity
JAV55_01355	COG4213	ABC transporter substrate-binding protein
JAV55_01370	COG4257	antibiotic catabolic process
JAV55_01380	COG0833	amino acid
JAV55_01385	COG2040	homocysteine
JAV55_01395	COG1263	PTS System
JAV55_01395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JAV55_01395	COG2190	(PTS) system
JAV55_01400	COG0789	Transcriptional regulator
JAV55_01405	COG2323	membrane
JAV55_01410	COG4451	ribulose bisphosphate carboxylase, small
JAV55_01410	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JAV55_01415	COG2205	protein histidine kinase activity
JAV55_01420	COG1115	amino acid carrier protein
JAV55_01425	COG2066	Belongs to the glutaminase family
JAV55_01430	COG4191	Histidine kinase
JAV55_01435	COG0784	Response regulator, receiver
JAV55_01460	COG3540	Alkaline phosphatase
JAV55_01465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JAV55_01470	COG0805	protein transport
JAV55_01475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JAV55_01480	COG1012	belongs to the aldehyde dehydrogenase family
JAV55_01485	COG2271	Major facilitator Superfamily
JAV55_01490	COG4948	Mandelate Racemase Muconate Lactonizing
JAV55_01495	COG2186	Transcriptional regulator
JAV55_01500	COG2721	sulfolactate sulfo-lyase activity
JAV55_01505	COG0745	RESPONSE REGULATOR receiver
JAV55_01510	COG2205	protein histidine kinase activity
JAV55_01515	COG1131	(ABC) transporter
JAV55_01540	COG3173	Aminoglycoside phosphotransferase
JAV55_01545	COG1846	Transcriptional regulator
JAV55_01550	COG0318	PFAM AMP-dependent synthetase and ligase
JAV55_01570	COG0789	Transcriptional regulator
JAV55_01595	COG0697	spore germination
JAV55_01600	COG1714	RDD family
JAV55_01605	COG1405	negative regulation of cell septum assembly
JAV55_01605	COG3012	SEC-C Motif Domain Protein
JAV55_01610	COG1131	(ABC) transporter
JAV55_01635	COG0583	DNA-binding transcription factor activity
JAV55_01640	COG1942	4-Oxalocrotonate Tautomerase
JAV55_01660	COG1288	antiporter activity
JAV55_01670	COG0456	acetyltransferase
JAV55_01680	COG1164	Oligoendopeptidase f
JAV55_01685	COG2261	transglycosylase associated protein
JAV55_01695	COG0247	lactate metabolic process
JAV55_01700	COG0277	FAD linked oxidase domain protein
JAV55_01705	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JAV55_01710	COG1447	Phosphotransferase system cellobiose-specific component IIA
JAV55_01715	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JAV55_01720	COG1486	melibiose metabolic process
JAV55_01725	COG2188	Transcriptional regulator
JAV55_01730	COG3394	polysaccharide catabolic process
JAV55_01745	COG3591	Belongs to the peptidase S1B family
JAV55_01750	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_01760	COG1595	DNA-templated transcription, initiation
JAV55_01770	COG3773	Cell wall hydrolase
JAV55_01775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JAV55_01780	COG0791	NLP P60 protein
JAV55_01780	COG3883	PFAM NLP P60 protein
JAV55_01790	COG1131	(ABC) transporter
JAV55_01795	COG1309	transcriptional regulator
JAV55_01815	COG2310	stress, protein
JAV55_01820	COG2310	stress, protein
JAV55_01825	COG2310	stress, protein
JAV55_01830	COG0861	Integral membrane protein TerC family
JAV55_01850	COG3853	Toxic anion resistance protein (TelA)
JAV55_01855	COG0785	Cytochrome C biogenesis protein
JAV55_01865	COG0789	Transcriptional regulator
JAV55_01870	COG2223	nitrite transmembrane transporter activity
JAV55_01875	COG0039	L-malate dehydrogenase activity
JAV55_01880	COG1620	l-lactate permease
JAV55_01885	COG1280	lysine exporter protein (LysE YggA)
JAV55_01890	COG1113	amino acid transport
JAV55_01895	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JAV55_01900	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JAV55_01905	COG3541	Predicted nucleotidyltransferase
JAV55_01910	COG0506	proline dehydrogenase activity
JAV55_01915	COG1012	belongs to the aldehyde dehydrogenase family
JAV55_01920	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JAV55_01925	COG2508	Transcriptional regulator
JAV55_01930	COG3689	TIGRFAM TIGR03943 family protein
JAV55_01935	COG0701	Predicted permease
JAV55_01940	COG3458	cephalosporin-C deacetylase activity
JAV55_01960	COG0765	amino acid transport
JAV55_01965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JAV55_01970	COG2249	NAD(P)H dehydrogenase (quinone) activity
JAV55_01980	COG2723	6-phospho-beta-galactosidase activity
JAV55_01990	COG3209	COG3209 Rhs family protein
JAV55_02000	COG3266	domain, Protein
JAV55_02000	COG0515	serine threonine protein kinase
JAV55_02010	COG5444	nuclease activity
JAV55_02035	COG1176	ABC-type spermidine putrescine transport system, permease component I
JAV55_02045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JAV55_02050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JAV55_02055	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JAV55_02060	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
JAV55_02065	COG0697	spore germination
JAV55_02070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JAV55_02080	COG2819	hydrolase of the alpha beta superfamily
JAV55_02090	COG2364	Membrane
JAV55_02100	COG1131	(ABC) transporter
JAV55_02130	COG1126	abc transporter atp-binding protein
JAV55_02135	COG0765	amino acid transport
JAV55_02140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JAV55_02145	COG3829	transcription factor binding
JAV55_02150	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JAV55_02155	COG0833	amino acid
JAV55_02160	COG0010	Belongs to the arginase family
JAV55_02165	COG0583	DNA-binding transcription factor activity
JAV55_02170	COG0163	prenyltransferase activity
JAV55_02175	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JAV55_02220	COG5444	nuclease activity
JAV55_02240	COG2972	Histidine kinase
JAV55_02245	COG2207	Transcriptional regulator
JAV55_02245	COG4753	response regulator
JAV55_02250	COG4213	ABC transporter substrate-binding protein
JAV55_02260	COG4214	carbohydrate transport
JAV55_02265	COG2271	Major facilitator Superfamily
JAV55_02270	COG0456	acetyltransferase
JAV55_02270	COG1846	Transcriptional regulator
JAV55_02275	COG1874	Beta-galactosidase
JAV55_02280	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
JAV55_02285	COG3104	oligopeptide transport
JAV55_02290	COG5434	Belongs to the glycosyl hydrolase 28 family
JAV55_02300	COG0697	spore germination
JAV55_02310	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JAV55_02320	COG1136	(ABC) transporter
JAV55_02325	COG0577	efflux transmembrane transporter activity
JAV55_02330	COG0745	RESPONSE REGULATOR receiver
JAV55_02335	COG3850	Histidine kinase
JAV55_02335	COG5002	protein histidine kinase activity
JAV55_02340	COG0840	transmembrane signaling receptor activity
JAV55_02345	COG0527	aspartate kinase activity
JAV55_02350	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JAV55_02355	COG4605	iron ion homeostasis
JAV55_02360	COG4604	ABC transporter, ATP-binding protein
JAV55_02365	COG4607	ABC-type enterochelin transport system periplasmic component
JAV55_02370	COG2814	Major facilitator Superfamily
JAV55_02375	COG1309	transcriptional regulator
JAV55_02385	COG0778	Nitroreductase
JAV55_02390	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
JAV55_02395	COG0640	Transcriptional regulator
JAV55_02400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JAV55_02405	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JAV55_02410	COG0531	amino acid
JAV55_02415	COG1012	belongs to the aldehyde dehydrogenase family
JAV55_02420	COG0697	spore germination
JAV55_02430	COG4549	nuclear export factor GLE1
JAV55_02435	COG2372	response to copper ion
JAV55_02435	COG1276	copper resistance
JAV55_02440	COG1349	DNA-binding transcription factor activity
JAV55_02445	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JAV55_02450	COG0243	molybdopterin cofactor binding
JAV55_02455	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JAV55_02460	COG2146	nitrite reductase [NAD(P)H] activity
JAV55_02465	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JAV55_02465	COG1587	Uroporphyrinogen-III synthase
JAV55_02470	COG1802	Transcriptional regulator
JAV55_02475	COG0471	metal ion transport
JAV55_02480	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JAV55_02485	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JAV55_02495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JAV55_02510	COG3959	Transketolase, thiamine diphosphate binding domain
JAV55_02515	COG3958	Transketolase
JAV55_02520	COG0561	phosphatase activity
JAV55_02525	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JAV55_02530	COG1914	H( )-stimulated, divalent metal cation uptake system
JAV55_02535	COG4336	lyase activity
JAV55_02540	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JAV55_02545	COG1984	allophanate hydrolase subunit 2
JAV55_02550	COG1414	Transcriptional regulator
JAV55_02555	COG2755	lipolytic protein G-D-S-L family
JAV55_02560	COG2213	PTS system mannitol-specific
JAV55_02565	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JAV55_02570	COG0246	Mannitol dehydrogenase
JAV55_02575	COG3711	transcriptional antiterminator
JAV55_02580	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_02585	COG1917	Cupin 2, conserved barrel domain protein
JAV55_02595	COG3871	stress protein (general stress protein 26)
JAV55_02610	COG2814	Major facilitator Superfamily
JAV55_02620	COG1522	sequence-specific DNA binding
JAV55_02625	COG0551	DNA topoisomerase type I activity
JAV55_02625	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JAV55_02630	COG0531	amino acid
JAV55_02635	COG0028	Belongs to the TPP enzyme family
JAV55_02640	COG3397	chitin binding
JAV55_02650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JAV55_02655	COG1914	H( )-stimulated, divalent metal cation uptake system
JAV55_02660	COG2261	transglycosylase associated protein
JAV55_02665	COG1027	Aspartate ammonia-lyase
JAV55_02670	COG1819	glycosyl
JAV55_02675	COG4876	unkown
JAV55_02680	COG2217	Heavy metal translocating P-type atpase
JAV55_02690	COG0662	Cupin 2, conserved barrel domain protein
JAV55_02695	COG3729	General stress protein
JAV55_02700	COG0628	permease
JAV55_02705	COG1301	dicarboxylic acid transport
JAV55_02710	COG1131	(ABC) transporter
JAV55_02715	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JAV55_02725	COG1960	acyl-CoA dehydrogenase activity
JAV55_02740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JAV55_02745	COG1181	Belongs to the D-alanine--D-alanine ligase family
JAV55_02750	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JAV55_02760	COG0513	Belongs to the DEAD box helicase family
JAV55_02765	COG3402	PFAM membrane-flanked domain
JAV55_02770	COG3428	Bacterial PH domain
JAV55_02775	COG0705	Rhomboid family
JAV55_02780	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
JAV55_02785	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JAV55_02790	COG0864	Transcriptional regulator
JAV55_02795	COG2337	Toxic component of a toxin-antitoxin (TA) module
JAV55_02800	COG1366	Belongs to the anti-sigma-factor antagonist family
JAV55_02805	COG1366	Belongs to the anti-sigma-factor antagonist family
JAV55_02810	COG2172	sigma factor antagonist activity
JAV55_02815	COG2208	phosphoserine phosphatase activity
JAV55_02825	COG2172	sigma factor antagonist activity
JAV55_02830	COG1191	sigma factor activity
JAV55_02835	COG2208	phosphoserine phosphatase activity
JAV55_02840	COG2183	response to ionizing radiation
JAV55_02845	COG1309	transcriptional regulator
JAV55_02850	COG1033	growth of symbiont in host cell
JAV55_02850	COG2409	Drug exporters of the RND superfamily
JAV55_02860	COG3091	SprT-like family
JAV55_02905	COG1476	TRANSCRIPTIONal
JAV55_02910	COG3239	Fatty acid desaturase
JAV55_02915	COG1278	Cold shock
JAV55_02920	COG1063	alcohol dehydrogenase
JAV55_02925	COG2364	Membrane
JAV55_02930	COG1846	Transcriptional regulator
JAV55_02935	COG0456	acetyltransferase
JAV55_02940	COG2808	Putative FMN-binding domain
JAV55_02950	COG1733	regulation of RNA biosynthetic process
JAV55_02955	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JAV55_02980	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
JAV55_02985	COG1113	amino acid transport
JAV55_03000	COG1595	DNA-templated transcription, initiation
JAV55_03010	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JAV55_03010	COG2755	lipolytic protein G-D-S-L family
JAV55_03015	COG2814	Major facilitator Superfamily
JAV55_03020	COG2972	Histidine kinase
JAV55_03020	COG0745	RESPONSE REGULATOR receiver
JAV55_03025	COG3279	Response regulator of the LytR AlgR family
JAV55_03035	COG3764	Sortase (surface protein transpeptidase)
JAV55_03040	COG2814	Major facilitator Superfamily
JAV55_03080	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JAV55_03085	COG0802	atpase or kinase
JAV55_03090	COG1214	PFAM Peptidase M22, glycoprotease
JAV55_03095	COG0456	acetyltransferase
JAV55_03100	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JAV55_03105	COG0488	(ABC) transporter
JAV55_03110	COG0315	cyclic pyranopterin monophosphate synthase activity
JAV55_03115	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JAV55_03120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JAV55_03125	COG0805	protein transport
JAV55_03135	COG1266	CAAX protease self-immunity
JAV55_03140	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JAV55_03145	COG0459	protein refolding
JAV55_03160	COG2720	vancomycin resistance protein
JAV55_03175	COG2135	peptidase activity
JAV55_03185	COG1309	transcriptional regulator
JAV55_03190	COG0574	Belongs to the PEP-utilizing enzyme family
JAV55_03190	COG3848	Pyruvate phosphate dikinase
JAV55_03200	COG3189	MarR family transcriptional regulator
JAV55_03205	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
JAV55_03210	COG2272	Belongs to the type-B carboxylesterase lipase family
JAV55_03215	COG2814	Major facilitator Superfamily
JAV55_03220	COG1842	Phage shock protein A
JAV55_03225	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JAV55_03230	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
JAV55_03235	COG4260	virion core protein, lumpy skin disease virus
JAV55_03245	COG1378	Sugar-specific transcriptional regulator TrmB
JAV55_03250	COG1280	lysine exporter protein (LysE YggA)
JAV55_03255	COG3339	Conserved Protein
JAV55_03260	COG0772	Belongs to the SEDS family
JAV55_03265	COG0772	Belongs to the SEDS family
JAV55_03285	COG0726	polysaccharide deacetylase
JAV55_03295	COG1609	Transcriptional regulator
JAV55_03300	COG0366	Alpha amylase catalytic
JAV55_03305	COG2182	Extracellular solute-binding protein
JAV55_03310	COG1175	transmembrane transport
JAV55_03315	COG3833	ABC-type maltose transport systems, permease component
JAV55_03320	COG5521	maltodextrose utilization protein MalA
JAV55_03325	COG1554	hydrolase, family 65, central catalytic
JAV55_03330	COG0366	Alpha amylase catalytic
JAV55_03335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JAV55_03340	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JAV55_03345	COG1846	Transcriptional regulator
JAV55_03360	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JAV55_03365	COG0823	Involved in the tonB-independent uptake of proteins
JAV55_03395	COG0702	epimerase
JAV55_03405	COG2132	Multicopper oxidase
JAV55_03420	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JAV55_03425	COG0714	Associated with various cellular activities
JAV55_03430	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
JAV55_03435	COG1305	Transglutaminase-like
JAV55_03440	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JAV55_03440	COG0519	Catalyzes the synthesis of GMP from XMP
JAV55_03445	COG2252	PERMEase
JAV55_03460	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
JAV55_03470	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JAV55_03475	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JAV55_03480	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JAV55_03485	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JAV55_03490	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JAV55_03495	COG0047	phosphoribosylformylglycinamidine synthase activity
JAV55_03500	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JAV55_03505	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JAV55_03510	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JAV55_03515	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JAV55_03520	COG0138	bifunctional purine biosynthesis protein purh
JAV55_03525	COG0151	Belongs to the GarS family
JAV55_03535	COG2124	cytochrome p450
JAV55_03555	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JAV55_03560	COG1470	cell adhesion involved in biofilm formation
JAV55_03565	COG4496	protein, YerC YecD
JAV55_03570	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
JAV55_03575	COG0210	DNA helicase
JAV55_03580	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JAV55_03585	COG4851	CamS sex pheromone cAM373 precursor
JAV55_03590	COG2188	Transcriptional regulator
JAV55_03610	COG1735	metal-dependent hydrolase with the TIM-barrel fold
JAV55_03615	COG0626	cystathionine gamma-synthase activity
JAV55_03620	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JAV55_03625	COG3457	Alanine racemase
JAV55_03630	COG0363	glucosamine-6-phosphate deaminase activity
JAV55_03635	COG1285	pathogenesis
JAV55_03640	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JAV55_03645	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JAV55_03650	COG0154	amidase activity
JAV55_03655	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JAV55_03670	COG4124	Belongs to the glycosyl hydrolase 26 family
JAV55_03675	COG1309	transcriptional regulator
JAV55_03680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JAV55_03690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JAV55_03695	COG1957	nucleoside hydrolase
JAV55_03700	COG1597	lipid kinase activity
JAV55_03705	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JAV55_03725	COG1263	PTS System
JAV55_03725	COG2190	(PTS) system
JAV55_03725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JAV55_03730	COG2723	6-phospho-beta-galactosidase activity
JAV55_03735	COG3711	transcriptional antiterminator
JAV55_03740	COG0457	Tetratricopeptide repeat
JAV55_03755	COG0217	transcriptional regulatory protein
JAV55_03770	COG1012	belongs to the aldehyde dehydrogenase family
JAV55_03775	COG0840	transmembrane signaling receptor activity
JAV55_03780	COG0471	metal ion transport
JAV55_03785	COG0488	(ABC) transporter
JAV55_03795	COG1469	GTP cyclohydrolase I activity
JAV55_03810	COG0523	cobalamin synthesis protein
JAV55_03815	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
JAV55_03820	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JAV55_03825	COG0156	8-amino-7-oxononanoate synthase activity
JAV55_03830	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JAV55_03835	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JAV55_03840	COG2124	cytochrome p450
JAV55_03850	COG0789	Transcriptional regulator
JAV55_03855	COG2814	Major facilitator Superfamily
JAV55_03860	COG0488	(ABC) transporter
JAV55_03865	COG0513	Belongs to the DEAD box helicase family
JAV55_03870	COG2130	NADP-dependent
JAV55_03885	COG0471	metal ion transport
JAV55_03905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JAV55_03915	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
JAV55_03920	COG5658	integral membrane protein
JAV55_03925	COG0640	Transcriptional regulator
JAV55_03930	COG1254	Belongs to the acylphosphatase family
JAV55_03935	COG2258	MOSC domain
JAV55_03950	COG0024	Methionine aminopeptidase
JAV55_03955	COG1368	sulfuric ester hydrolase activity
JAV55_03965	COG1115	amino acid carrier protein
JAV55_03970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JAV55_03970	COG1263	PTS System
JAV55_03975	COG0366	Alpha amylase catalytic
JAV55_03980	COG2188	Transcriptional regulator
JAV55_04005	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JAV55_04010	COG1045	serine acetyltransferase
JAV55_04015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JAV55_04025	COG1215	transferase activity, transferring glycosyl groups
JAV55_04030	COG0463	Glycosyl transferase, family 2
JAV55_04030	COG0457	Tetratricopeptide repeat
JAV55_04040	COG0673	inositol 2-dehydrogenase activity
JAV55_04050	COG0657	acetylesterase activity
JAV55_04055	COG1733	regulation of RNA biosynthetic process
JAV55_04060	COG0778	Nitroreductase
JAV55_04065	COG0737	Belongs to the 5'-nucleotidase family
JAV55_04070	COG0693	protein deglycase activity
JAV55_04075	COG4840	Belongs to the UPF0435 family
JAV55_04080	COG1115	amino acid carrier protein
JAV55_04085	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JAV55_04090	COG4980	gas vesicle protein
JAV55_04095	COG1295	ribonuclease BN
JAV55_04100	COG0477	Major facilitator Superfamily
JAV55_04110	COG0387	Pfam Sodium calcium exchanger
JAV55_04120	COG0535	radical SAM domain protein
JAV55_04130	COG0726	polysaccharide deacetylase
JAV55_04135	COG0371	Dehydrogenase
JAV55_04145	COG0598	Magnesium transport protein CorA
JAV55_04150	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JAV55_04155	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JAV55_04160	COG4637	Psort location Cytoplasmic, score
JAV55_04185	COG1819	glycosyl
JAV55_04195	COG0477	Major facilitator Superfamily
JAV55_04200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JAV55_04200	COG1263	PTS System
JAV55_04205	COG3711	transcriptional antiterminator
JAV55_04210	COG0288	reversible hydration of carbon dioxide
JAV55_04215	COG3002	Belongs to the UPF0753 family
JAV55_04220	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JAV55_04225	COG5609	conserved protein (DUF2294)
JAV55_04235	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JAV55_04240	COG0022	dehydrogenase e1 component
JAV55_04245	COG0508	dehydrogenase complex catalyzes the overall conversion of
JAV55_04250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JAV55_04255	COG3284	Transcriptional regulator
JAV55_04260	COG1742	UPF0060 membrane protein
JAV55_04265	COG1486	melibiose metabolic process
JAV55_04270	COG1737	Transcriptional regulator
JAV55_04275	COG1263	PTS System
JAV55_04275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JAV55_04290	COG1733	regulation of RNA biosynthetic process
JAV55_04295	COG2259	Doxx family
JAV55_04300	COG2514	catechol 2,3-dioxygenase activity
JAV55_04310	COG3507	Belongs to the glycosyl hydrolase 43 family
JAV55_04315	COG2207	Transcriptional regulator
JAV55_04315	COG1917	Cupin 2, conserved barrel domain protein
JAV55_04320	COG1653	transport
JAV55_04325	COG2249	NAD(P)H dehydrogenase (quinone) activity
JAV55_04330	COG1051	belongs to the nudix hydrolase family
JAV55_04340	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JAV55_04340	COG0392	lysyltransferase activity
JAV55_04345	COG0384	phenazine biosynthesis protein PhzF
JAV55_04350	COG0778	Nitroreductase
JAV55_04370	COG1090	epimerase
JAV55_04375	COG2137	regulation of response to DNA damage stimulus
JAV55_04400	COG0463	Glycosyl transferase, family 2
JAV55_04410	COG4485	Bacterial membrane protein, YfhO
JAV55_04415	COG1988	membrane-bound metal-dependent
JAV55_04420	COG1194	a g-specific adenine glycosylase
JAV55_04430	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_04445	COG3557	Belongs to the UPF0374 family
JAV55_04450	COG1132	(ABC) transporter
JAV55_04455	COG0444	Belongs to the ABC transporter superfamily
JAV55_04460	COG4608	Belongs to the ABC transporter superfamily
JAV55_04465	COG0747	negative chemotaxis
JAV55_04470	COG0601	transmembrane transport
JAV55_04475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JAV55_04480	COG4129	membrane
JAV55_04485	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JAV55_04490	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JAV55_04495	COG0735	belongs to the Fur family
JAV55_04605	COG0457	Tetratricopeptide repeat
JAV55_04630	COG5444	nuclease activity
JAV55_04635	COG0457	Tetratricopeptide repeat
JAV55_04640	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JAV55_04650	COG0710	3-dehydroquinate dehydratase activity
JAV55_04655	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JAV55_04660	COG1116	anion transmembrane transporter activity
JAV55_04665	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JAV55_04670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JAV55_04675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JAV55_04685	COG1476	TRANSCRIPTIONal
JAV55_04695	COG1131	(ABC) transporter
JAV55_04715	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JAV55_04725	COG3382	B3 4 domain protein
JAV55_04730	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JAV55_04740	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JAV55_04745	COG0789	Transcriptional regulator
JAV55_04750	COG1664	Polymer-forming cytoskeletal
JAV55_04760	COG2766	serine protein kinase
JAV55_04765	COG2718	Belongs to the UPF0229 family
JAV55_04770	COG1566	PFAM secretion protein HlyD family protein
JAV55_04775	COG2814	Major facilitator Superfamily
JAV55_04780	COG0655	NAD(P)H dehydrogenase (quinone) activity
JAV55_04790	COG1131	(ABC) transporter
JAV55_04795	COG1131	(ABC) transporter
JAV55_04800	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JAV55_04805	COG1278	Cold shock
JAV55_04810	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JAV55_04815	COG2011	ABC-type metal ion transport system permease component
JAV55_04820	COG1464	Belongs to the NlpA lipoprotein family
JAV55_04825	COG1823	symporter activity
JAV55_04850	COG5577	PFAM Coat F domain
JAV55_04855	COG5002	protein histidine kinase activity
JAV55_04860	COG0737	Belongs to the 5'-nucleotidase family
JAV55_04860	COG1525	nuclease
JAV55_04860	COG4085	toxin activity
JAV55_04865	COG3764	Sortase (surface protein transpeptidase)
JAV55_04870	COG0564	pseudouridine synthase activity
JAV55_04880	COG0517	IMP dehydrogenase activity
JAV55_04885	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JAV55_04890	COG3153	acetyltransferase
JAV55_04890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JAV55_04895	COG0488	(ABC) transporter
JAV55_04900	COG2116	formate transmembrane transporter activity
JAV55_04905	COG0679	Auxin Efflux Carrier
JAV55_04910	COG0604	alcohol dehydrogenase
JAV55_04915	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
JAV55_04920	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JAV55_04925	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JAV55_04930	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JAV55_04935	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JAV55_04950	COG2203	Gaf domain
JAV55_04950	COG4585	Histidine kinase
JAV55_04955	COG2197	response regulator
JAV55_04960	COG0431	NADPH-dependent FMN reductase
JAV55_04975	COG1959	2 iron, 2 sulfur cluster binding
JAV55_04980	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JAV55_04980	COG1017	nitric oxide dioxygenase activity
JAV55_04985	COG2719	SpoVR family
JAV55_04990	COG0791	NLP P60 protein
JAV55_04990	COG1388	LysM domain
JAV55_04995	COG0583	DNA-binding transcription factor activity
JAV55_05000	COG0372	Belongs to the citrate synthase family
JAV55_05005	COG2133	pyrroloquinoline quinone binding
JAV55_05010	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_05015	COG0733	neurotransmitter:sodium symporter activity
JAV55_05025	COG3708	Transcriptional regulator
JAV55_05025	COG2207	Transcriptional regulator
JAV55_05030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JAV55_05050	COG1595	DNA-templated transcription, initiation
JAV55_05055	COG0662	Cupin 2, conserved barrel domain protein
JAV55_05060	COG0204	Acyl-transferase
JAV55_05065	COG3152	Membrane
JAV55_05075	COG1309	transcriptional regulator
JAV55_05080	COG1253	flavin adenine dinucleotide binding
JAV55_05085	COG0789	Transcriptional regulator
JAV55_05090	COG1253	flavin adenine dinucleotide binding
JAV55_05110	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JAV55_05115	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JAV55_05120	COG0584	glycerophosphoryl diester phosphodiesterase
JAV55_05130	COG0668	transmembrane transport
JAV55_05135	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JAV55_05145	COG0726	polysaccharide deacetylase
JAV55_05155	COG1757	Na H antiporter
JAV55_05160	COG2017	converts alpha-aldose to the beta-anomer
JAV55_05185	COG0589	response to stress
JAV55_05190	COG1132	(ABC) transporter
JAV55_05195	COG1132	(ABC) transporter
JAV55_05220	COG3842	ATPase activity
JAV55_05225	COG2508	Transcriptional regulator
JAV55_05235	COG0189	ligase activity
JAV55_05240	COG0189	ligase activity
JAV55_05245	COG4399	Belongs to the UPF0754 family
JAV55_05250	COG3679	Belongs to the UPF0342 family
JAV55_05255	COG0561	phosphatase activity
JAV55_05260	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JAV55_05265	COG0475	glutathione-regulated potassium exporter activity
JAV55_05270	COG0490	domain, Protein
JAV55_05280	COG1024	Enoyl-CoA hydratase
JAV55_05285	COG0457	Tetratricopeptide repeat
JAV55_05305	COG4152	abc transporter atp-binding protein
JAV55_05310	COG1668	transmembrane transport
JAV55_05315	COG0420	3'-5' exonuclease activity
JAV55_05320	COG4717	serine-type aminopeptidase activity
JAV55_05325	COG3481	metal-dependent phosphohydrolase, HD sub domain
JAV55_05335	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JAV55_05365	COG1846	Transcriptional regulator
JAV55_05370	COG4980	gas vesicle protein
JAV55_05380	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JAV55_05385	COG0537	adenosine 5'-monophosphoramidase activity
JAV55_05390	COG1131	(ABC) transporter
JAV55_05395	COG4473	ABC transporter
JAV55_05405	COG1473	amidohydrolase
JAV55_05410	COG3069	C4-dicarboxylate transmembrane transporter activity
JAV55_05415	COG2329	Antibiotic biosynthesis monooxygenase
JAV55_05420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JAV55_05425	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JAV55_05430	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JAV55_05435	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JAV55_05440	COG1309	transcriptional regulator
JAV55_05445	COG1511	domain protein
JAV55_05450	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JAV55_05455	COG1363	Peptidase, m42
JAV55_05465	COG1301	dicarboxylic acid transport
JAV55_05475	COG1234	tRNA 3'-trailer cleavage
JAV55_05480	COG0095	Lipoate-protein ligase
JAV55_05485	COG0318	PFAM AMP-dependent synthetase and ligase
JAV55_05495	COG1396	sequence-specific DNA binding
JAV55_05510	COG0501	Belongs to the peptidase M48B family
JAV55_05520	COG0697	spore germination
JAV55_05525	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JAV55_05530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JAV55_05535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JAV55_05540	COG0406	alpha-ribazole phosphatase activity
JAV55_05545	COG0840	transmembrane signaling receptor activity
JAV55_05550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JAV55_05550	COG0723	plastoquinol--plastocyanin reductase activity
JAV55_05555	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_05565	COG4903	ComK protein
JAV55_05575	COG0398	Pfam SNARE associated Golgi protein
JAV55_05580	COG0681	Belongs to the peptidase S26 family
JAV55_05585	COG1404	Belongs to the peptidase S8 family
JAV55_05595	COG2508	Transcriptional regulator
JAV55_05605	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JAV55_05615	COG3257	ureidoglycine aminohydrolase activity
JAV55_05620	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
JAV55_05625	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
JAV55_05630	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JAV55_05635	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JAV55_05645	COG0549	Belongs to the carbamate kinase family
JAV55_05650	COG2814	Major facilitator Superfamily
JAV55_05660	COG0457	Tetratricopeptide repeat
JAV55_05675	COG1609	Transcriptional regulator
JAV55_05680	COG1653	transport
JAV55_05685	COG1175	transmembrane transport
JAV55_05690	COG0395	ABC-type sugar transport system, permease component
JAV55_05695	COG1486	melibiose metabolic process
JAV55_05700	COG3180	Ammonia monooxygenase
JAV55_05715	COG3546	catalase activity
JAV55_05720	COG0318	PFAM AMP-dependent synthetase and ligase
JAV55_05725	COG0477	Major facilitator Superfamily
JAV55_05725	COG2814	Major facilitator Superfamily
JAV55_05735	COG5002	protein histidine kinase activity
JAV55_05740	COG0745	RESPONSE REGULATOR receiver
JAV55_05745	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
JAV55_05750	COG0725	ABC transporter, periplasmic molybdate-binding protein
JAV55_05755	COG4149	molybdate abc transporter
JAV55_05760	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JAV55_05765	COG1074	ATP-dependent DNA helicase activity
JAV55_05770	COG0420	3'-5' exonuclease activity
JAV55_05775	COG0419	ATPase involved in DNA repair
JAV55_05830	COG0179	Fumarylacetoacetate (FAA) hydrolase
JAV55_05850	COG0367	asparagine synthase
JAV55_05855	COG0004	ammonium transporteR
JAV55_05865	COG0534	Mate efflux family protein
JAV55_05870	COG1917	Cupin 2, conserved barrel domain protein
JAV55_05870	COG2207	Transcriptional regulator
JAV55_05885	COG0673	inositol 2-dehydrogenase activity
JAV55_05905	COG1279	arginine transmembrane transporter activity
JAV55_05910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JAV55_05920	COG0076	glutamate decarboxylase activity
JAV55_05945	COG2153	protein acetylation
JAV55_05950	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_05955	COG2378	regulation of single-species biofilm formation
JAV55_05960	COG0646	methionine synthase
JAV55_05960	COG1410	methionine synthase
JAV55_05965	COG0646	methionine synthase
JAV55_05965	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JAV55_05970	COG1666	GTP binding
JAV55_05975	COG2996	Protein conserved in bacteria
JAV55_05990	COG1307	EDD domain protein, DegV family
JAV55_05995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JAV55_06005	COG0516	GMP reductase activity
JAV55_06020	COG0561	phosphatase activity
JAV55_06025	COG1073	alpha beta
JAV55_06030	COG2151	metal-sulfur cluster biosynthetic enzyme
JAV55_06035	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JAV55_06040	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JAV55_06045	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JAV55_06050	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JAV55_06055	COG0505	Belongs to the CarA family
JAV55_06060	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JAV55_06065	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JAV55_06070	COG1968	undecaprenyl-diphosphatase activity
JAV55_06085	COG2267	carboxylic ester hydrolase activity
JAV55_06095	COG1744	ABC transporter substrate-binding protein PnrA-like
JAV55_06110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JAV55_06115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JAV55_06120	COG5504	Zn-dependent protease
JAV55_06125	COG0444	Belongs to the ABC transporter superfamily
JAV55_06130	COG4608	Belongs to the ABC transporter superfamily
JAV55_06140	COG0601	transmembrane transport
JAV55_06145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JAV55_06170	COG0180	Tryptophanyl-tRNA synthetase
JAV55_06175	COG4166	transmembrane transport
JAV55_06180	COG0601	transmembrane transport
JAV55_06185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JAV55_06190	COG0444	Belongs to the ABC transporter superfamily
JAV55_06195	COG4608	Belongs to the ABC transporter superfamily
JAV55_06200	COG0456	acetyltransferase
JAV55_06205	COG1393	Belongs to the ArsC family
JAV55_06210	COG0861	Integral membrane protein TerC family
JAV55_06220	COG4862	establishment of competence for transformation
JAV55_06240	COG4565	transcriptional regulatory protein
JAV55_06245	COG3290	protein histidine kinase activity
JAV55_06250	COG4469	Competence protein
JAV55_06255	COG1164	Oligoendopeptidase f
JAV55_06260	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JAV55_06265	COG2346	COG2346, Truncated hemoglobins
JAV55_06270	COG0741	lytic transglycosylase activity
JAV55_06275	COG4116	CYTH
JAV55_06285	COG2357	RelA SpoT domain protein
JAV55_06290	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JAV55_06295	COG0564	pseudouridine synthase activity
JAV55_06300	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JAV55_06305	COG0475	glutathione-regulated potassium exporter activity
JAV55_06305	COG0569	domain protein
JAV55_06310	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JAV55_06315	COG0352	thiamine-phosphate diphosphorylase activity
JAV55_06325	COG2104	thiamine diphosphate biosynthetic process
JAV55_06330	COG2022	thiamine diphosphate biosynthetic process
JAV55_06335	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JAV55_06340	COG0351	phosphomethylpyrimidine kinase
JAV55_06345	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JAV55_06400	COG0210	DNA helicase
JAV55_06410	COG0586	Pfam SNARE associated Golgi protein
JAV55_06415	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JAV55_06420	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JAV55_06425	COG2246	polysaccharide biosynthetic process
JAV55_06430	COG2153	protein acetylation
JAV55_06435	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JAV55_06440	COG2382	esterase
JAV55_06455	COG0626	cystathionine gamma-synthase activity
JAV55_06460	COG0626	cystathionine gamma-synthase activity
JAV55_06465	COG5505	Protein of unknown function (DUF819)
JAV55_06485	COG3507	Belongs to the glycosyl hydrolase 43 family
JAV55_06490	COG0582	viral genome integration into host DNA
JAV55_06510	COG1476	TRANSCRIPTIONal
JAV55_06550	COG5377	YqaJ viral recombinase family
JAV55_06555	COG3723	Recombinational DNA repair protein, rece pathway
JAV55_06570	COG0305	Participates in initiation and elongation during chromosome replication
JAV55_06585	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
JAV55_06630	COG0457	Tetratricopeptide repeat
JAV55_06685	COG5518	Phage portal protein
JAV55_06690	COG2369	cell adhesion
JAV55_06700	COG0338	D12 class N6 adenine-specific DNA methyltransferase
JAV55_06705	COG4653	Phage capsid family
JAV55_06760	COG3953	SLT domain
JAV55_06760	COG5280	Phage tail tape measure protein TP901
JAV55_06760	COG3953	SLT domain
JAV55_06760	COG5280	Phage tail tape measure protein TP901
JAV55_06765	COG1652	LysM domain
JAV55_06770	COG4193	domain, Protein
JAV55_06780	COG3628	GPW Gp25 family protein
JAV55_06785	COG3299	homolog of phage Mu protein gp47
JAV55_06790	COG3778	Protein conserved in bacteria
JAV55_06840	COG2337	Toxic component of a toxin-antitoxin (TA) module
JAV55_06865	COG0110	maltose O-acetyltransferase activity
JAV55_06875	COG0583	DNA-binding transcription factor activity
JAV55_06880	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JAV55_06885	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JAV55_06890	COG0583	DNA-binding transcription factor activity
JAV55_06895	COG0697	spore germination
JAV55_06900	COG0346	lactoylglutathione lyase activity
JAV55_06910	COG3584	3D domain protein
JAV55_06910	COG1388	LysM domain
JAV55_06915	COG2814	Major facilitator Superfamily
JAV55_06920	COG1309	transcriptional regulator
JAV55_06940	COG5444	nuclease activity
JAV55_06945	COG4195	phage-related replication protein
JAV55_06950	COG2856	Zn peptidase
JAV55_06955	COG1396	sequence-specific DNA binding
JAV55_06970	COG1522	sequence-specific DNA binding
JAV55_06975	COG1484	DNA-dependent DNA replication
JAV55_06995	COG1595	DNA-templated transcription, initiation
JAV55_07000	COG5484	DNA packaging
JAV55_07000	COG3728	DNA packaging
JAV55_07005	COG1783	phage Terminase large subunit
JAV55_07010	COG5518	Phage portal protein
JAV55_07015	COG0338	D12 class N6 adenine-specific DNA methyltransferase
JAV55_07020	COG4653	Phage capsid family
JAV55_07075	COG1652	LysM domain
JAV55_07080	COG4193	domain, Protein
JAV55_07090	COG3628	GPW Gp25 family protein
JAV55_07095	COG3299	homolog of phage Mu protein gp47
JAV55_07100	COG3778	Protein conserved in bacteria
JAV55_07135	COG1802	Transcriptional regulator
JAV55_07140	COG1063	alcohol dehydrogenase
JAV55_07145	COG1312	Catalyzes the dehydration of D-mannonate
JAV55_07150	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_07155	COG1063	alcohol dehydrogenase
JAV55_07160	COG2271	Major facilitator Superfamily
JAV55_07175	COG0306	phosphate transporter
JAV55_07180	COG1392	Phosphate transport regulator
JAV55_07185	COG0405	Gamma-glutamyltransferase
JAV55_07190	COG5578	integral membrane protein
JAV55_07195	COG2972	Histidine kinase
JAV55_07200	COG2207	Transcriptional regulator
JAV55_07200	COG4753	response regulator
JAV55_07205	COG1653	transport
JAV55_07210	COG1175	transmembrane transport
JAV55_07215	COG0395	ABC-type sugar transport system, permease component
JAV55_07220	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
JAV55_07225	COG2207	Transcriptional regulator
JAV55_07230	COG2755	lipolytic protein G-D-S-L family
JAV55_07240	COG5578	integral membrane protein
JAV55_07245	COG3401	FG-GAP repeat protein
JAV55_07255	COG2755	lipolytic protein G-D-S-L family
JAV55_07260	COG3401	FG-GAP repeat protein
JAV55_07265	COG0667	Aldo Keto reductase
JAV55_07270	COG2755	lipolytic protein G-D-S-L family
JAV55_07275	COG1874	Beta-galactosidase
JAV55_07285	COG1653	transport
JAV55_07290	COG4209	transmembrane transport
JAV55_07295	COG0395	ABC-type sugar transport system, permease component
JAV55_07300	COG0531	amino acid
JAV55_07305	COG0346	lactoylglutathione lyase activity
JAV55_07315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JAV55_07320	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JAV55_07325	COG2362	D-Aminopeptidase
JAV55_07330	COG0601	transmembrane transport
JAV55_07335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JAV55_07340	COG0444	Belongs to the ABC transporter superfamily
JAV55_07345	COG4166	transmembrane transport
JAV55_07350	COG1619	proteins homologs of microcin C7 resistance protein MccF
JAV55_07355	COG4948	Mandelate Racemase Muconate Lactonizing
JAV55_07360	COG0791	NLP P60 protein
JAV55_07365	COG4608	Belongs to the ABC transporter superfamily
JAV55_07370	COG1834	amidinotransferase
JAV55_07375	COG1607	acyl-coa hydrolase
JAV55_07405	COG2318	DinB family
JAV55_07410	COG2076	Multidrug Resistance protein
JAV55_07415	COG2076	Multidrug Resistance protein
JAV55_07420	COG0788	formyltetrahydrofolate deformylase activity
JAV55_07425	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JAV55_07430	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JAV55_07435	COG1764	response to oxidative stress
JAV55_07440	COG1846	Transcriptional regulator
JAV55_07445	COG1764	response to oxidative stress
JAV55_07455	COG0590	tRNA wobble adenosine to inosine editing
JAV55_07460	COG0406	alpha-ribazole phosphatase activity
JAV55_07475	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JAV55_07480	COG1404	Belongs to the peptidase S8 family
JAV55_07490	COG2239	Acts as a magnesium transporter
JAV55_07500	COG0789	Transcriptional regulator
JAV55_07515	COG1846	Transcriptional regulator
JAV55_07520	COG1793	dna ligase
JAV55_07520	COG3285	dna ligase
JAV55_07525	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
JAV55_07530	COG5001	Diguanylate cyclase
JAV55_07530	COG3300	MHYT domain
JAV55_07535	COG0586	Pfam SNARE associated Golgi protein
JAV55_07540	COG0861	Integral membrane protein TerC family
JAV55_07545	COG1191	sigma factor activity
JAV55_07565	COG0501	Belongs to the peptidase M48B family
JAV55_07570	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JAV55_07575	COG0768	penicillin binding
JAV55_07590	COG3594	Acyltransferase
JAV55_07595	COG5002	protein histidine kinase activity
JAV55_07600	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JAV55_07605	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JAV55_07610	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
JAV55_07615	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JAV55_07620	COG0436	Aminotransferase
JAV55_07625	COG1850	ribulose-bisphosphate carboxylase activity
JAV55_07630	COG0235	Class ii aldolase
JAV55_07630	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
JAV55_07635	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
JAV55_07640	COG0346	lactoylglutathione lyase activity
JAV55_07645	COG3339	Conserved Protein
JAV55_07655	COG3852	Histidine kinase
JAV55_07660	COG1846	Transcriptional regulator
JAV55_07665	COG1360	Flagellar Motor Protein
JAV55_07670	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JAV55_07675	COG0542	response to heat
JAV55_07680	COG3949	Membrane
JAV55_07685	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JAV55_07690	COG0720	synthase
JAV55_07695	COG0602	queuosine metabolic process
JAV55_07700	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JAV55_07710	COG3739	integral membrane protein
JAV55_07715	COG3655	Transcriptional regulator
JAV55_07750	COG4873	Protein conserved in bacteria
JAV55_07760	COG3773	Cell wall hydrolase
JAV55_07765	COG2244	polysaccharide biosynthetic process
JAV55_07770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JAV55_07775	COG2217	Heavy metal translocating P-type atpase
JAV55_07780	COG0006	proline dipeptidase activity
JAV55_07790	COG1609	Transcriptional regulator
JAV55_07795	COG3711	transcriptional antiterminator
JAV55_07800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JAV55_07800	COG2190	(PTS) system
JAV55_07800	COG1263	PTS System
JAV55_07805	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JAV55_07810	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JAV55_07820	COG1533	DNA photolyase activity
JAV55_07825	COG0456	acetyltransferase
JAV55_07830	COG0840	transmembrane signaling receptor activity
JAV55_07835	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_07840	COG2084	Dehydrogenase
JAV55_07845	COG2340	Cysteine-rich secretory protein family
JAV55_07850	COG0768	penicillin binding
JAV55_07855	COG4191	Histidine kinase
JAV55_07860	COG0436	Aminotransferase
JAV55_07870	COG1714	RDD family
JAV55_07880	COG0835	chemotaxis
JAV55_07880	COG0784	Response regulator, receiver
JAV55_07890	COG2814	Major facilitator Superfamily
JAV55_07895	COG1376	ErfK ybiS ycfS ynhG family protein
JAV55_07900	COG1408	metallophosphoesterase
JAV55_07905	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_07910	COG2200	EAL domain
JAV55_07920	COG4703	Protein of unknown function (DUF1797)
JAV55_07930	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
JAV55_07940	COG0517	IMP dehydrogenase activity
JAV55_07945	COG0583	DNA-binding transcription factor activity
JAV55_07950	COG0716	FMN binding
JAV55_07960	COG0716	FMN binding
JAV55_07965	COG2171	N-acyltransferase activity
JAV55_07970	COG1473	amidohydrolase
JAV55_07980	COG0450	alkyl hydroperoxide reductase
JAV55_07985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JAV55_08000	COG0746	molybdenum cofactor guanylyltransferase activity
JAV55_08005	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JAV55_08010	COG0303	'Molybdopterin
JAV55_08015	COG1763	Mo-molybdopterin cofactor biosynthetic process
JAV55_08020	COG0314	molybdopterin synthase activity
JAV55_08025	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JAV55_08035	COG1132	(ABC) transporter
JAV55_08040	COG1132	(ABC) transporter
JAV55_08050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JAV55_08055	COG1136	(ABC) transporter
JAV55_08060	COG0577	efflux transmembrane transporter activity
JAV55_08065	COG1349	DNA-binding transcription factor activity
JAV55_08070	COG1105	Belongs to the carbohydrate kinase PfkB family
JAV55_08075	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JAV55_08075	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JAV55_08075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JAV55_08095	COG0488	(ABC) transporter
JAV55_08105	COG2309	aminopeptidase activity
JAV55_08115	COG1077	Cell shape determining protein MreB Mrl
JAV55_08120	COG2002	toxin-antitoxin pair type II binding
JAV55_08125	COG3852	Histidine kinase
JAV55_08130	COG0569	domain protein
JAV55_08135	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JAV55_08140	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JAV55_08145	COG5503	Protein of unknown function (DUF1447)
JAV55_08150	COG0561	phosphatase activity
JAV55_08160	COG0242	peptide deformylase activity
JAV55_08170	COG0497	DNA recombination
JAV55_08175	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JAV55_08180	COG0022	dehydrogenase e1 component
JAV55_08185	COG0508	dehydrogenase complex catalyzes the overall conversion of
JAV55_08190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JAV55_08195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JAV55_08205	COG1982	Orn Lys Arg decarboxylase major
JAV55_08210	COG4476	Belongs to the UPF0223 family
JAV55_08215	COG4493	Belongs to the UPF0637 family
JAV55_08225	COG0483	inositol monophosphate 1-phosphatase activity
JAV55_08245	COG1595	DNA-templated transcription, initiation
JAV55_08260	COG1217	gtp-binding protein TYPA
JAV55_08270	COG1846	Transcriptional regulator
JAV55_08275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JAV55_08280	COG4896	Protein conserved in bacteria
JAV55_08290	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JAV55_08295	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JAV55_08300	COG2066	Belongs to the glutaminase family
JAV55_08305	COG4838	Belongs to the UPF0358 family
JAV55_08310	COG0772	Belongs to the SEDS family
JAV55_08315	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JAV55_08320	COG1612	heme a metabolic process
JAV55_08325	COG0109	protoheme IX farnesyltransferase activity
JAV55_08330	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JAV55_08330	COG2010	Cytochrome c
JAV55_08335	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JAV55_08340	COG1845	cytochrome c oxidase, subunit III
JAV55_08345	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JAV55_08350	COG3336	cytochrome c oxidase
JAV55_08360	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
JAV55_08365	COG2340	Cysteine-rich secretory protein family
JAV55_08380	COG3679	Belongs to the UPF0342 family
JAV55_08385	COG4471	UPF0298 protein
JAV55_08390	COG0742	ribosomal rna small subunit methyltransferase
JAV55_08395	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JAV55_08400	COG3314	Sporulation integral membrane protein YlbJ
JAV55_08405	COG3480	Lon protease (S16) C-terminal proteolytic domain
JAV55_08410	COG1323	Belongs to the UPF0348 family
JAV55_08415	COG1399	metal-binding, possibly nucleic acid-binding protein
JAV55_08420	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JAV55_08430	COG0454	-acetyltransferase
JAV55_08435	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JAV55_08440	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
JAV55_08445	COG2001	Belongs to the MraZ family
JAV55_08450	COG0275	rRNA processing
JAV55_08455	COG4839	cell division protein FtsL
JAV55_08460	COG0768	penicillin binding
JAV55_08465	COG0768	penicillin binding
JAV55_08470	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JAV55_08475	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JAV55_08480	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JAV55_08485	COG0772	Belongs to the SEDS family
JAV55_08490	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JAV55_08495	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JAV55_08500	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JAV55_08505	COG3879	Bacterial protein of unknown function (DUF881)
JAV55_08510	COG3879	Bacterial protein of unknown function (DUF881)
JAV55_08515	COG3856	small basic protein
JAV55_08520	COG0849	cell division
JAV55_08525	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JAV55_08530	COG1404	Belongs to the peptidase S8 family
JAV55_08530	COG4412	M6 family metalloprotease domain protein
JAV55_08535	COG1404	Belongs to the peptidase S8 family
JAV55_08535	COG4412	M6 family metalloprotease domain protein
JAV55_08545	COG1191	sigma factor activity
JAV55_08550	COG1191	sigma factor activity
JAV55_08555	COG1119	ATPase activity
JAV55_08560	COG0500	methyltransferase
JAV55_08565	COG1873	PFAM PRC-barrel domain
JAV55_08570	COG1496	oxidoreductase activity
JAV55_08575	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JAV55_08580	COG1799	cell septum assembly
JAV55_08585	COG0762	integral membrane protein
JAV55_08590	COG2302	S4 RNA-binding domain
JAV55_08595	COG3599	regulation of cell shape
JAV55_08600	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JAV55_08605	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JAV55_08610	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JAV55_08615	COG0564	pseudouridine synthase activity
JAV55_08620	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JAV55_08625	COG2233	PERMEase
JAV55_08630	COG0540	Belongs to the ATCase OTCase family
JAV55_08635	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JAV55_08640	COG0505	Belongs to the CarA family
JAV55_08645	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JAV55_08650	COG0543	2 iron, 2 sulfur cluster binding
JAV55_08655	COG0167	dihydroorotate dehydrogenase activity
JAV55_08660	COG0284	orotidine-5'-phosphate decarboxylase activity
JAV55_08665	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JAV55_08675	COG0175	sulfate reduction
JAV55_08680	COG0306	phosphate transporter
JAV55_08685	COG2046	Belongs to the sulfate adenylyltransferase family
JAV55_08690	COG0529	Catalyzes the synthesis of activated sulfate
JAV55_08695	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JAV55_08700	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
JAV55_08705	COG1648	precorrin-2 dehydrogenase activity
JAV55_08715	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JAV55_08720	COG1561	YicC-like family, N-terminal region
JAV55_08725	COG2052	Domain of unknown function (DUF370)
JAV55_08730	COG0194	GDP metabolic process
JAV55_08735	COG1758	RNA polymerase activity
JAV55_08740	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JAV55_08745	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JAV55_08750	COG0242	peptide deformylase activity
JAV55_08755	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JAV55_08760	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JAV55_08760	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JAV55_08765	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JAV55_08770	COG0631	protein serine/threonine phosphatase activity
JAV55_08775	COG2815	serine threonine protein kinase
JAV55_08775	COG0515	serine threonine protein kinase
JAV55_08780	COG1162	GTPase activity
JAV55_08785	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JAV55_08790	COG1564	THIamine pyrophosphokinase
JAV55_08800	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JAV55_08805	COG1302	Protein conserved in bacteria
JAV55_08810	COG1461	Dihydroxyacetone kinase
JAV55_08815	COG1760	l-serine dehydratase
JAV55_08820	COG1760	l-serine dehydratase
JAV55_08825	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JAV55_08830	COG1349	DNA-binding transcription factor activity
JAV55_08835	COG0416	fatty acid biosynthetic process
JAV55_08840	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JAV55_08845	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_08850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JAV55_08855	COG0571	ribonuclease III activity
JAV55_08860	COG1196	nuclear chromosome segregation
JAV55_08865	COG0552	protein localization to endoplasmic reticulum
JAV55_08870	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JAV55_08875	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JAV55_08880	COG0228	four-way junction DNA binding
JAV55_08885	COG1837	Belongs to the UPF0109 family
JAV55_08895	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JAV55_08900	COG0336	Belongs to the RNA methyltransferase TrmD family
JAV55_08905	COG0335	large ribosomal subunit rRNA binding
JAV55_08910	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JAV55_08915	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JAV55_08925	COG2257	FlhB HrpN YscU SpaS Family
JAV55_08930	COG0045	succinate-CoA ligase (ADP-forming) activity
JAV55_08935	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JAV55_08940	COG0758	DNA mediated transformation
JAV55_08945	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JAV55_08950	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JAV55_08955	COG4974	Belongs to the 'phage' integrase family
JAV55_08960	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JAV55_08965	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JAV55_08970	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JAV55_08975	COG1815	bacterial-type flagellum-dependent cell motility
JAV55_08980	COG1558	bacterial-type flagellum-dependent cell motility
JAV55_08985	COG1677	Flagellar hook-basal body complex protein FliE
JAV55_08990	COG1766	The M ring may be actively involved in energy transduction
JAV55_08995	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JAV55_09000	COG1317	bacterial-type flagellum organization
JAV55_09005	COG1157	protein secretion by the type III secretion system
JAV55_09010	COG2882	bacterial-type flagellum organization
JAV55_09020	COG3144	bacterial-type flagellum assembly
JAV55_09025	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
JAV55_09030	COG4786	Flagellar basal body rod
JAV55_09035	COG1582	Flagellar protein (FlbD)
JAV55_09040	COG1580	Controls the rotational direction of flagella during chemotaxis
JAV55_09045	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JAV55_09050	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JAV55_09050	COG1776	CheC inhibitor of MCP methylation
JAV55_09055	COG2201	protein-glutamate methylesterase activity
JAV55_09060	COG3190	flagellar
JAV55_09065	COG1338	Plays a role in the flagellum-specific transport system
JAV55_09070	COG1987	bacterial-type flagellum assembly
JAV55_09075	COG1684	flagellar biosynthetic protein fliR
JAV55_09080	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JAV55_09085	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JAV55_09090	COG1419	protein localization to endoplasmic reticulum
JAV55_09095	COG0455	bacterial-type flagellum organization
JAV55_09100	COG2201	protein-glutamate methylesterase activity
JAV55_09105	COG0643	Histidine kinase
JAV55_09105	COG2198	Histidine kinase
JAV55_09110	COG0835	chemotaxis
JAV55_09115	COG1776	CheC inhibitor of MCP methylation
JAV55_09120	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
JAV55_09125	COG1191	sigma factor activity
JAV55_09135	COG0052	Belongs to the universal ribosomal protein uS2 family
JAV55_09140	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JAV55_09145	COG0528	UMP kinase activity
JAV55_09150	COG0233	cytoplasmic translational termination
JAV55_09155	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JAV55_09160	COG4589	Belongs to the CDS family
JAV55_09165	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JAV55_09170	COG0750	zinc metalloprotease
JAV55_09175	COG0442	prolyl-tRNA aminoacylation
JAV55_09180	COG2176	DNA-directed DNA polymerase activity
JAV55_09205	COG0779	Required for maturation of 30S ribosomal subunits
JAV55_09210	COG0195	Participates in both transcription termination and antitermination
JAV55_09215	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JAV55_09220	COG1358	cellular component organization or biogenesis
JAV55_09225	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JAV55_09230	COG1550	Protein conserved in bacteria
JAV55_09235	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JAV55_09240	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JAV55_09245	COG0196	riboflavin kinase activity
JAV55_09250	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JAV55_09255	COG1185	polyribonucleotide nucleotidyltransferase activity
JAV55_09260	COG0726	polysaccharide deacetylase
JAV55_09265	COG0612	Peptidase, M16
JAV55_09270	COG1873	PFAM PRC-barrel domain
JAV55_09275	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JAV55_09280	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JAV55_09285	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JAV55_09290	COG0527	aspartate kinase activity
JAV55_09300	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JAV55_09305	COG0740	serine-type endopeptidase activity
JAV55_09315	COG1674	ftsk spoiiie
JAV55_09315	COG4980	gas vesicle protein
JAV55_09320	COG2188	Transcriptional regulator
JAV55_09325	COG2814	Major facilitator Superfamily
JAV55_09330	COG0612	Peptidase, M16
JAV55_09335	COG0612	Peptidase, M16
JAV55_09340	COG0300	oxidoreductase activity
JAV55_09355	COG1426	Protein conserved in bacteria
JAV55_09360	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JAV55_09365	COG1546	Belongs to the CinA family
JAV55_09365	COG1058	Belongs to the CinA family
JAV55_09375	COG1418	mRNA catabolic process
JAV55_09380	COG1692	metallophosphoesterase
JAV55_09385	COG2359	stage V sporulation protein S
JAV55_09395	COG1063	alcohol dehydrogenase
JAV55_09400	COG0156	8-amino-7-oxononanoate synthase activity
JAV55_09405	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JAV55_09410	COG4550	Control of competence regulator ComK, YlbF/YmcA
JAV55_09420	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JAV55_09425	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JAV55_09430	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
JAV55_09435	COG5444	nuclease activity
JAV55_09450	COG0523	cobalamin synthesis protein
JAV55_09460	COG1247	-acetyltransferase
JAV55_09480	COG3619	membrane
JAV55_09485	COG3263	regulation of cellular component size
JAV55_09505	COG0393	Putative heavy-metal-binding
JAV55_09510	COG0398	Pfam SNARE associated Golgi protein
JAV55_09515	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JAV55_09520	COG1819	glycosyl
JAV55_09525	COG0531	amino acid
JAV55_09530	COG5577	PFAM Coat F domain
JAV55_09540	COG1388	LysM domain
JAV55_09540	COG3858	chitin binding
JAV55_09545	COG1309	transcriptional regulator
JAV55_09550	COG3631	Ketosteroid isomerase-related protein
JAV55_09555	COG0702	epimerase
JAV55_09565	COG1764	response to oxidative stress
JAV55_09570	COG2076	Multidrug Resistance protein
JAV55_09575	COG2076	Multidrug Resistance protein
JAV55_09590	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JAV55_09595	COG1923	regulation of RNA biosynthetic process
JAV55_09605	COG1780	Probably involved in ribonucleotide reductase function
JAV55_09610	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JAV55_09615	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JAV55_09620	COG4112	unkown
JAV55_09635	COG0735	belongs to the Fur family
JAV55_09640	COG1802	Transcriptional regulator
JAV55_09645	COG0697	spore germination
JAV55_09675	COG1309	transcriptional regulator
JAV55_09720	COG0464	growth
JAV55_09725	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JAV55_09730	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
JAV55_09735	COG0789	Transcriptional regulator
JAV55_09740	COG0174	glutamine synthetase
JAV55_09775	COG1073	alpha beta
JAV55_09820	COG1309	transcriptional regulator
JAV55_09825	COG2076	Multidrug Resistance protein
JAV55_09830	COG2076	Multidrug Resistance protein
JAV55_09835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JAV55_09855	COG3546	catalase activity
JAV55_09880	COG1846	Transcriptional regulator
JAV55_09885	COG0778	Nitroreductase
JAV55_09890	COG0346	lactoylglutathione lyase activity
JAV55_09895	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JAV55_09900	COG0655	NAD(P)H dehydrogenase (quinone) activity
JAV55_09925	COG3209	COG3209 Rhs family protein
JAV55_09930	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JAV55_09935	COG1388	LysM domain
JAV55_09940	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JAV55_09945	COG4224	UPF0291 protein
JAV55_09950	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JAV55_09960	COG3763	UPF0154 protein
JAV55_09970	COG0785	Cytochrome C biogenesis protein
JAV55_09975	COG2201	protein-glutamate methylesterase activity
JAV55_09980	COG4846	Membrane protein involved in cytochrome C biogenesis
JAV55_09990	COG0071	Belongs to the small heat shock protein (HSP20) family
JAV55_10005	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JAV55_10010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JAV55_10030	COG0824	Thioesterase
JAV55_10055	COG4841	protein insertion into membrane
JAV55_10060	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JAV55_10065	COG1832	CoA-binding protein
JAV55_10070	COG0187	DNA topoisomerase II activity
JAV55_10075	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JAV55_10080	COG1609	Transcriptional regulator
JAV55_10095	COG2160	L-arabinose isomerase activity
JAV55_10115	COG1115	amino acid carrier protein
JAV55_10125	COG2181	nitrate reductase activity
JAV55_10130	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
JAV55_10135	COG1140	nitrate reductase beta subunit
JAV55_10140	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JAV55_10155	COG0535	radical SAM domain protein
JAV55_10160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JAV55_10170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JAV55_10175	COG2223	nitrite transmembrane transporter activity
JAV55_10195	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
JAV55_10205	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JAV55_10215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JAV55_10230	COG3420	alginic acid biosynthetic process
JAV55_10235	COG1114	Component of the transport system for branched-chain amino acids
JAV55_10245	COG0789	Transcriptional regulator
JAV55_10270	COG1024	Enoyl-CoA hydratase
JAV55_10275	COG1012	belongs to the aldehyde dehydrogenase family
JAV55_10280	COG2084	Dehydrogenase
JAV55_10285	COG1960	acyl-CoA dehydrogenase activity
JAV55_10290	COG1482	cell wall glycoprotein biosynthetic process
JAV55_10295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JAV55_10295	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JAV55_10295	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JAV55_10315	COG3711	transcriptional antiterminator
JAV55_10315	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JAV55_10330	COG1725	Transcriptional regulator
JAV55_10335	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_10340	COG1312	Catalyzes the dehydration of D-mannonate
JAV55_10355	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
JAV55_10365	COG1609	Transcriptional regulator
JAV55_10370	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JAV55_10375	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JAV55_10380	COG0640	Transcriptional regulator
JAV55_10385	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
JAV55_10400	COG1649	PFAM Uncharacterised BCR, COG1649
JAV55_10405	COG2404	hydrolase activity, acting on ester bonds
JAV55_10410	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JAV55_10420	COG2027	D-alanyl-D-alanine carboxypeptidase
JAV55_10425	COG1252	NADH dehydrogenase
JAV55_10435	COG0166	Belongs to the GPI family
JAV55_10445	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JAV55_10450	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JAV55_10455	COG1024	Enoyl-CoA hydratase
JAV55_10460	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JAV55_10465	COG0511	ligase activity, forming carbon-carbon bonds
JAV55_10470	COG0439	Biotin carboxylase
JAV55_10475	COG0318	PFAM AMP-dependent synthetase and ligase
JAV55_10480	COG1960	acyl-CoA dehydrogenase activity
JAV55_10485	COG2249	NAD(P)H dehydrogenase (quinone) activity
JAV55_10490	COG1733	regulation of RNA biosynthetic process
JAV55_10495	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JAV55_10500	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JAV55_10510	COG2323	membrane
JAV55_10520	COG0306	phosphate transporter
JAV55_10525	COG0175	sulfate reduction
JAV55_10530	COG1809	phosphosulfolactate synthase activity
JAV55_10535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JAV55_10540	COG4948	Mandelate Racemase Muconate Lactonizing
JAV55_10545	COG2814	Major facilitator Superfamily
JAV55_10550	COG0463	Glycosyl transferase, family 2
JAV55_10560	COG0493	'glutamate synthase
JAV55_10565	COG0069	glutamate synthase activity
JAV55_10565	COG0067	glutamate synthase
JAV55_10565	COG0070	glutamate synthase
JAV55_10570	COG0583	DNA-binding transcription factor activity
JAV55_10590	COG1846	Transcriptional regulator
JAV55_10600	COG1132	(ABC) transporter
JAV55_10610	COG0300	oxidoreductase activity
JAV55_10615	COG0574	Belongs to the PEP-utilizing enzyme family
JAV55_10615	COG3848	Pyruvate phosphate dikinase
JAV55_10620	COG0477	Major facilitator Superfamily
JAV55_10625	COG0243	molybdopterin cofactor binding
JAV55_10630	COG1846	Transcriptional regulator
JAV55_10640	COG0531	amino acid
JAV55_10650	COG0531	amino acid
JAV55_10655	COG0531	amino acid
JAV55_10660	COG0697	spore germination
JAV55_10665	COG0488	(ABC) transporter
JAV55_10670	COG0840	transmembrane signaling receptor activity
JAV55_10675	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JAV55_10680	COG1404	Belongs to the peptidase S8 family
JAV55_10690	COG1309	transcriptional regulator
JAV55_10695	COG1846	Transcriptional regulator
JAV55_10725	COG1309	transcriptional regulator
JAV55_10735	COG3708	Transcriptional regulator
JAV55_10745	COG2378	regulation of single-species biofilm formation
JAV55_10755	COG0640	Transcriptional regulator
JAV55_10760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JAV55_10770	COG0531	amino acid
JAV55_10775	COG0741	lytic transglycosylase activity
JAV55_10780	COG1086	Polysaccharide biosynthesis protein
JAV55_10800	COG2322	membrane
JAV55_10815	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JAV55_10820	COG3584	3D domain protein
JAV55_10820	COG1388	LysM domain
JAV55_10825	COG0514	ATP-dependent DNA helicase (RecQ)
JAV55_10860	COG2427	Protein of unknown function (DUF1641)
JAV55_10865	COG3383	formate dehydrogenase (NAD+) activity
JAV55_10880	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
JAV55_10920	COG0402	S-adenosylhomocysteine deaminase activity
JAV55_10935	COG2267	carboxylic ester hydrolase activity
JAV55_10950	COG1280	lysine exporter protein (LysE YggA)
JAV55_10955	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JAV55_10965	COG3848	Pyruvate phosphate dikinase
JAV55_10965	COG0574	Belongs to the PEP-utilizing enzyme family
JAV55_10970	COG1309	transcriptional regulator
JAV55_10985	COG2318	DinB family
JAV55_10990	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JAV55_10995	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JAV55_11010	COG1012	belongs to the aldehyde dehydrogenase family
JAV55_11015	COG2814	Major facilitator Superfamily
JAV55_11030	COG1657	PFAM Prenyltransferase squalene oxidase
JAV55_11035	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JAV55_11045	COG0733	neurotransmitter:sodium symporter activity
JAV55_11050	COG0385	Bile acid
JAV55_11055	COG0508	dehydrogenase complex catalyzes the overall conversion of
JAV55_11060	COG0567	Dehydrogenase, E1 component
JAV55_11065	COG4548	von Willebrand factor, type A
JAV55_11070	COG0714	Associated with various cellular activities
JAV55_11075	COG2032	superoxide dismutase activity
JAV55_11080	COG0791	NLP P60 protein
JAV55_11080	COG1388	LysM domain
JAV55_11085	COG0534	Mate efflux family protein
JAV55_11090	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JAV55_11095	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JAV55_11105	COG2962	Rard protein
JAV55_11115	COG4305	rare lipoprotein A
JAV55_11130	COG1733	regulation of RNA biosynthetic process
JAV55_11135	COG0778	Nitroreductase
JAV55_11140	COG0400	carboxylic ester hydrolase activity
JAV55_11150	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JAV55_11155	COG0793	Belongs to the peptidase S41A family
JAV55_11155	COG3409	Peptidoglycan-binding domain 1 protein
JAV55_11160	COG2226	methyltransferase
JAV55_11170	COG1876	peptidase activity
JAV55_11175	COG0813	purine-nucleoside phosphorylase activity
JAV55_11180	COG0701	Predicted permease
JAV55_11200	COG0671	phosphoesterase, PA-phosphatase related
JAV55_11215	COG4479	Belongs to the UPF0346 family
JAV55_11225	COG1509	lysine 2,3-aminomutase activity
JAV55_11230	COG0456	acetyltransferase
JAV55_11235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JAV55_11240	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JAV55_11245	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JAV55_11250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JAV55_11265	COG0456	acetyltransferase
JAV55_11270	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JAV55_11275	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JAV55_11280	COG1846	Transcriptional regulator
JAV55_11290	COG3706	GGDEF domain
JAV55_11295	COG0534	Mate efflux family protein
JAV55_11310	COG4698	Protein conserved in bacteria
JAV55_11315	COG2755	lipolytic protein G-D-S-L family
JAV55_11320	COG1999	signal sequence binding
JAV55_11335	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JAV55_11340	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JAV55_11345	COG1272	protein, Hemolysin III
JAV55_11350	COG0204	Acyl-transferase
JAV55_11355	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JAV55_11360	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JAV55_11370	COG2521	methyltransferase
JAV55_11370	COG2136	Putative SAM-dependent methyltransferase
JAV55_11380	COG0129	dihydroxy-acid dehydratase activity
JAV55_11385	COG1413	lyase activity
JAV55_11390	COG1418	mRNA catabolic process
JAV55_11395	COG0386	Belongs to the glutathione peroxidase family
JAV55_11400	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JAV55_11405	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
JAV55_11410	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JAV55_11420	COG1278	Cold shock
JAV55_11440	COG0328	RNA-DNA hybrid ribonuclease activity
JAV55_11445	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JAV55_11450	COG0328	RNA-DNA hybrid ribonuclease activity
JAV55_11460	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JAV55_11475	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JAV55_11485	COG1755	Isoprenylcysteine carboxyl methyltransferase
JAV55_11490	COG3424	synthase
JAV55_11495	COG0456	acetyltransferase
JAV55_11500	COG2233	PERMEase
JAV55_11505	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JAV55_11510	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JAV55_11515	COG1199	ATP-dependent helicase activity
JAV55_11530	COG0116	Belongs to the methyltransferase superfamily
JAV55_11540	COG3599	regulation of cell shape
JAV55_11545	COG4474	Belongs to the UPF0398 family
JAV55_11555	COG3359	exonuclease
JAV55_11560	COG1205	dead DEAH box helicase
JAV55_11560	COG1111	helicase
JAV55_11565	COG2190	(PTS) system
JAV55_11570	COG0071	Belongs to the small heat shock protein (HSP20) family
JAV55_11605	COG3331	DNA recombination
JAV55_11610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JAV55_11610	COG4499	WXG100 protein secretion system (Wss), protein YukC
JAV55_11620	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JAV55_11625	COG3935	DnaD domain protein
JAV55_11630	COG0017	Asparaginyl-tRNA synthetase
JAV55_11635	COG0436	Aminotransferase
JAV55_11640	COG5353	protein conserved in bacteria
JAV55_11650	COG1199	ATP-dependent helicase activity
JAV55_11650	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JAV55_11655	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JAV55_11660	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JAV55_11665	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JAV55_11675	COG0617	tRNA 3'-terminal CCA addition
JAV55_11680	COG0438	transferase activity, transferring glycosyl groups
JAV55_11685	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JAV55_11690	COG1803	Methylglyoxal synthase
JAV55_11695	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JAV55_11700	COG1694	Mazg nucleotide pyrophosphohydrolase
JAV55_11705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JAV55_11715	COG4347	Protein of unknown function (DUF1405)
JAV55_11725	COG2010	Cytochrome c
JAV55_11725	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JAV55_11730	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JAV55_11735	COG0723	plastoquinol--plastocyanin reductase activity
JAV55_11745	COG5582	Belongs to the UPF0302 family
JAV55_11750	COG0457	Tetratricopeptide repeat
JAV55_11755	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JAV55_11760	COG0287	Prephenate dehydrogenase
JAV55_11765	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JAV55_11770	COG0159	tryptophan synthase activity
JAV55_11775	COG0133	tryptophan synthase activity
JAV55_11780	COG0135	phosphoribosylanthranilate isomerase activity
JAV55_11785	COG0134	indole-3-glycerol-phosphate synthase activity
JAV55_11790	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JAV55_11795	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JAV55_11800	COG4401	Chorismate mutase type I
JAV55_11805	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JAV55_11810	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JAV55_11815	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JAV55_11820	COG0105	UTP biosynthetic process
JAV55_11825	COG0142	geranyltranstransferase activity
JAV55_11830	COG2226	methyltransferase
JAV55_11835	COG0142	geranyltranstransferase activity
JAV55_11850	COG0776	regulation of translation
JAV55_11855	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JAV55_11870	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JAV55_11875	COG1160	GTP binding
JAV55_11900	COG1304	FMN binding
JAV55_11905	COG0539	negative regulation of cytoplasmic translation
JAV55_11910	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JAV55_11920	COG2959	enzyme of heme biosynthesis
JAV55_11925	COG3773	Cell wall hydrolase
JAV55_11925	COG3409	Peptidoglycan-binding domain 1 protein
JAV55_11930	COG2339	peptidase activity
JAV55_11940	COG0492	ferredoxin-NADP+ reductase activity
JAV55_11945	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JAV55_11980	COG4955	Helix-turn-helix domain
JAV55_11985	COG1141	Ferredoxin
JAV55_11990	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JAV55_12000	COG0739	heme binding
JAV55_12010	COG1595	DNA-templated transcription, initiation
JAV55_12030	COG5002	protein histidine kinase activity
JAV55_12035	COG0745	RESPONSE REGULATOR receiver
JAV55_12040	COG5002	protein histidine kinase activity
JAV55_12045	COG0745	RESPONSE REGULATOR receiver
JAV55_12050	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JAV55_12055	COG1333	cytochrome c biogenesis protein
JAV55_12060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JAV55_12065	COG1187	pseudouridine synthase activity
JAV55_12070	COG0700	Nucleoside recognition
JAV55_12075	COG2715	membrane protein required for spore maturation
JAV55_12080	COG1686	Belongs to the peptidase S11 family
JAV55_12090	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JAV55_12095	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JAV55_12105	COG1547	Domain of unknown function (DUF309)
JAV55_12110	COG0456	acetyltransferase
JAV55_12115	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JAV55_12120	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JAV55_12120	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JAV55_12125	COG0307	riboflavin synthase, alpha
JAV55_12130	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JAV55_12130	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JAV55_12155	COG0457	Tetratricopeptide repeat
JAV55_12160	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JAV55_12165	COG4086	secreted protein
JAV55_12170	COG4195	phage-related replication protein
JAV55_12175	COG0019	diaminopimelate decarboxylase activity
JAV55_12190	COG0697	spore germination
JAV55_12205	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JAV55_12240	COG1686	Belongs to the peptidase S11 family
JAV55_12245	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JAV55_12250	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JAV55_12255	COG4974	Belongs to the 'phage' integrase family
JAV55_12265	COG0735	belongs to the Fur family
JAV55_12270	COG1300	Membrane
JAV55_12275	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JAV55_12295	COG2153	protein acetylation
JAV55_12300	COG1379	DNA repair
JAV55_12305	COG0494	nUDIX hydrolase
JAV55_12315	COG1309	transcriptional regulator
JAV55_12325	COG0667	Aldo Keto reductase
JAV55_12335	COG1073	alpha beta
JAV55_12345	COG4918	Iron-sulphur cluster biosynthesis
JAV55_12360	COG2329	Antibiotic biosynthesis monooxygenase
JAV55_12365	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
JAV55_12375	COG0747	negative chemotaxis
JAV55_12380	COG0601	transmembrane transport
JAV55_12390	COG0444	Belongs to the ABC transporter superfamily
JAV55_12400	COG0534	Mate efflux family protein
JAV55_12415	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JAV55_12425	COG2211	Major facilitator Superfamily
JAV55_12430	COG0346	lactoylglutathione lyase activity
JAV55_12435	COG1072	(Pantothenic acid kinase))
JAV55_12445	COG1131	(ABC) transporter
JAV55_12465	COG4195	phage-related replication protein
JAV55_12470	COG0300	oxidoreductase activity
JAV55_12475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JAV55_12480	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JAV55_12485	COG4187	Peptidase family M20/M25/M40
JAV55_12490	COG1902	pentaerythritol trinitrate reductase activity
JAV55_12495	COG0596	Alpha beta hydrolase
JAV55_12500	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JAV55_12505	COG1234	tRNA 3'-trailer cleavage
JAV55_12510	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JAV55_12525	COG2358	TRAP transporter, solute receptor (TAXI family
JAV55_12530	COG2188	Transcriptional regulator
JAV55_12535	COG2723	6-phospho-beta-galactosidase activity
JAV55_12540	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JAV55_12545	COG1447	Phosphotransferase system cellobiose-specific component IIA
JAV55_12550	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JAV55_12555	COG1785	Belongs to the alkaline phosphatase family
JAV55_12560	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_12565	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JAV55_12570	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JAV55_12580	COG0706	membrane insertase activity
JAV55_12585	COG2195	Cleaves the N-terminal amino acid of tripeptides
JAV55_12590	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JAV55_12600	COG4129	membrane
JAV55_12605	COG1126	abc transporter atp-binding protein
JAV55_12610	COG0765	amino acid transport
JAV55_12615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JAV55_12630	COG1597	lipid kinase activity
JAV55_12635	COG0508	dehydrogenase complex catalyzes the overall conversion of
JAV55_12640	COG0022	dehydrogenase e1 component
JAV55_12645	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JAV55_12650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JAV55_12655	COG3426	butyrate kinase activity
JAV55_12665	COG0280	phosphate acetyltransferase
JAV55_12670	COG3290	protein histidine kinase activity
JAV55_12670	COG3829	transcription factor binding
JAV55_12680	COG0584	glycerophosphoryl diester phosphodiesterase
JAV55_12685	COG0860	N-Acetylmuramoyl-L-alanine amidase
JAV55_12700	COG1045	serine acetyltransferase
JAV55_12710	COG0745	RESPONSE REGULATOR receiver
JAV55_12715	COG0750	zinc metalloprotease
JAV55_12720	COG0497	DNA recombination
JAV55_12725	COG1438	arginine binding
JAV55_12730	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
JAV55_12735	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JAV55_12740	COG0142	geranyltranstransferase activity
JAV55_12745	COG1722	exodeoxyribonuclease VII activity
JAV55_12750	COG1570	exodeoxyribonuclease VII activity
JAV55_12755	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JAV55_12760	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JAV55_12765	COG1302	Protein conserved in bacteria
JAV55_12770	COG0439	Biotin carboxylase
JAV55_12775	COG0511	ligase activity, forming carbon-carbon bonds
JAV55_12815	COG3854	ATPases associated with a variety of cellular activities
JAV55_12825	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JAV55_12830	COG0006	proline dipeptidase activity
JAV55_12835	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JAV55_12845	COG3872	metal-dependent enzyme
JAV55_12855	COG1752	Esterase of the alpha-beta hydrolase superfamily
JAV55_12860	COG1321	iron dependent repressor
JAV55_12865	COG0095	Lipoate-protein ligase
JAV55_12870	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JAV55_12875	COG2113	Glycine betaine
JAV55_12880	COG4176	ABC-type proline glycine betaine transport system permease component
JAV55_12885	COG4175	Glycine betaine
JAV55_12885	COG0517	IMP dehydrogenase activity
JAV55_12890	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JAV55_12895	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JAV55_12900	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JAV55_12905	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JAV55_12930	COG0681	Belongs to the peptidase S26 family
JAV55_12955	COG4940	Competence protein ComGF
JAV55_12965	COG4970	Tfp pilus assembly protein FimT
JAV55_12970	COG4537	Required for transformation and DNA binding
JAV55_12975	COG1459	type II secretion system
JAV55_12980	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JAV55_12985	COG1366	Belongs to the anti-sigma-factor antagonist family
JAV55_12995	COG1393	Belongs to the ArsC family
JAV55_13005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JAV55_13015	COG0011	TIGRFAM Protein of
JAV55_13025	COG2866	Carboxypeptidase
JAV55_13030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JAV55_13040	COG1368	sulfuric ester hydrolase activity
JAV55_13045	COG1940	carbohydrate kinase activity
JAV55_13050	COG4483	Protein conserved in bacteria
JAV55_13055	COG0697	spore germination
JAV55_13060	COG0705	Rhomboid family
JAV55_13060	COG0457	Tetratricopeptide repeat
JAV55_13070	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JAV55_13075	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JAV55_13080	COG0438	transferase activity, transferring glycosyl groups
JAV55_13095	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JAV55_13100	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JAV55_13105	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JAV55_13110	COG0581	inorganic phosphate transmembrane transporter activity
JAV55_13115	COG0573	inorganic phosphate transmembrane transporter activity
JAV55_13120	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JAV55_13125	COG0768	penicillin binding
JAV55_13130	COG0477	Major facilitator Superfamily
JAV55_13135	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JAV55_13140	COG2839	Protein conserved in bacteria
JAV55_13145	COG5521	maltodextrose utilization protein MalA
JAV55_13150	COG1388	LysM domain
JAV55_13155	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JAV55_13160	COG4709	membrane
JAV55_13165	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
JAV55_13170	COG0735	belongs to the Fur family
JAV55_13175	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JAV55_13180	COG1121	(ABC) transporter
JAV55_13185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JAV55_13195	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JAV55_13200	COG0513	Belongs to the DEAD box helicase family
JAV55_13210	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JAV55_13215	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JAV55_13220	COG2384	SAM-dependent methyltransferase
JAV55_13265	COG5444	nuclease activity
JAV55_13280	COG2010	Cytochrome c
JAV55_13285	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JAV55_13290	COG0358	DNA primase activity
JAV55_13295	COG1671	Belongs to the UPF0178 family
JAV55_13300	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JAV55_13305	COG0517	IMP dehydrogenase activity
JAV55_13310	COG0751	glycine-tRNA ligase activity
JAV55_13315	COG0752	glycyl-tRNA synthetase alpha subunit
JAV55_13320	COG1381	Involved in DNA repair and RecF pathway recombination
JAV55_13330	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JAV55_13335	COG0295	cytidine deaminase activity
JAV55_13340	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JAV55_13345	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JAV55_13350	COG1480	7TM receptor with intracellular HD hydrolase
JAV55_13355	COG1702	phosphate starvation-inducible protein PhoH
JAV55_13360	COG0561	phosphatase activity
JAV55_13375	COG4864	UPF0365 protein
JAV55_13380	COG1030	water channel activity
JAV55_13385	COG1610	YqeY-like protein
JAV55_13390	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JAV55_13395	COG1283	sodium-dependent phosphate transmembrane transporter activity
JAV55_13400	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JAV55_13405	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JAV55_13410	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JAV55_13415	COG2264	protein methyltransferase activity
JAV55_13420	COG0484	heat shock protein binding
JAV55_13425	COG0443	Heat shock 70 kDa protein
JAV55_13430	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JAV55_13435	COG1420	regulation of RNA biosynthetic process
JAV55_13440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JAV55_13445	COG0481	GTPase activity
JAV55_13455	COG0860	N-Acetylmuramoyl-L-alanine amidase
JAV55_13460	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
JAV55_13465	COG0268	Binds directly to 16S ribosomal RNA
JAV55_13470	COG1466	dna polymerase III delta subunit
JAV55_13480	COG2333	competence protein COMEC
JAV55_13480	COG0658	competence protein
JAV55_13485	COG2131	deaminase
JAV55_13490	COG1555	photosystem II stabilization
JAV55_13490	COG1596	polysaccharide export
JAV55_13495	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JAV55_13500	COG2226	methyltransferase
JAV55_13505	COG0799	negative regulation of ribosome biogenesis
JAV55_13510	COG1713	HD superfamily hydrolase involved in NAD metabolism
JAV55_13515	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JAV55_13520	COG1534	Rna-binding protein
JAV55_13525	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JAV55_13530	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JAV55_13535	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JAV55_13550	COG2755	lipolytic protein G-D-S-L family
JAV55_13555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JAV55_13560	COG5609	conserved protein (DUF2294)
JAV55_13565	COG3383	formate dehydrogenase (NAD+) activity
JAV55_13570	COG2427	Protein of unknown function (DUF1641)
JAV55_13600	COG0860	N-Acetylmuramoyl-L-alanine amidase
JAV55_13665	COG2197	response regulator
JAV55_13670	COG4585	Histidine kinase
JAV55_13675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JAV55_13680	COG0730	response to heat
JAV55_13685	COG0425	Belongs to the sulfur carrier protein TusA family
JAV55_13690	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JAV55_13690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JAV55_13695	COG0425	Belongs to the sulfur carrier protein TusA family
JAV55_13695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JAV55_13700	COG2210	Belongs to the sulfur carrier protein TusA family
JAV55_13705	COG1937	Protein conserved in bacteria
JAV55_13750	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JAV55_13755	COG0113	porphobilinogen synthase activity
JAV55_13760	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JAV55_13765	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
JAV55_13770	COG1733	regulation of RNA biosynthetic process
JAV55_13775	COG3239	Fatty acid desaturase
JAV55_13780	COG4585	Histidine kinase
JAV55_13785	COG2197	response regulator
JAV55_13790	COG0492	ferredoxin-NADP+ reductase activity
JAV55_13795	COG0747	negative chemotaxis
JAV55_13800	COG0601	transmembrane transport
JAV55_13805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JAV55_13810	COG0444	Belongs to the ABC transporter superfamily
JAV55_13815	COG4608	Belongs to the ABC transporter superfamily
JAV55_13835	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_13850	COG2124	cytochrome p450
JAV55_13855	COG0730	response to heat
JAV55_13865	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_13870	COG1621	beta-fructofuranosidase activity
JAV55_13875	COG3716	PTS system mannose fructose sorbose family IID component
JAV55_13880	COG3715	PTS system
JAV55_13885	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JAV55_13890	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
JAV55_13895	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JAV55_13895	COG3933	PFAM sigma-54 factor interaction domain-containing protein
JAV55_13920	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JAV55_13925	COG0656	L-ascorbic acid biosynthetic process
JAV55_13930	COG2814	Major facilitator Superfamily
JAV55_13935	COG1733	regulation of RNA biosynthetic process
JAV55_13940	COG3340	Belongs to the peptidase S51 family
JAV55_13945	COG1587	Uroporphyrinogen-III synthase
JAV55_13955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JAV55_13960	COG0583	DNA-binding transcription factor activity
JAV55_13965	COG2814	Major facilitator Superfamily
JAV55_13975	COG2124	cytochrome p450
JAV55_13975	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JAV55_13980	COG1309	transcriptional regulator
JAV55_13985	COG1404	Belongs to the peptidase S8 family
JAV55_13990	COG2226	methyltransferase
JAV55_14015	COG0626	cystathionine gamma-synthase activity
JAV55_14020	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JAV55_14025	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JAV55_14030	COG2226	methyltransferase
JAV55_14045	COG0768	penicillin binding
JAV55_14050	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JAV55_14055	COG0572	uridine kinase
JAV55_14060	COG0826	peptidase U32
JAV55_14065	COG0826	peptidase U32
JAV55_14070	COG4122	O-methyltransferase activity
JAV55_14075	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JAV55_14080	COG3906	Belongs to the UPF0473 family
JAV55_14085	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JAV55_14090	COG4472	Bacterial protein of unknown function (DUF965)
JAV55_14095	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JAV55_14100	COG0628	permease
JAV55_14115	COG3881	PFAM PRC-barrel domain
JAV55_14120	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JAV55_14125	COG0457	Tetratricopeptide repeat
JAV55_14130	COG0482	sulfurtransferase activity
JAV55_14135	COG1104	cysteine desulfurase activity
JAV55_14140	COG1959	2 iron, 2 sulfur cluster binding
JAV55_14145	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JAV55_14150	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JAV55_14160	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JAV55_14165	COG0124	histidyl-tRNA synthetase
JAV55_14175	COG0860	N-Acetylmuramoyl-L-alanine amidase
JAV55_14175	COG4991	sh3 domain protein
JAV55_14175	COG3103	Sh3 type 3 domain protein
JAV55_14180	COG1490	D-aminoacyl-tRNA deacylase activity
JAV55_14185	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JAV55_14190	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JAV55_14195	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JAV55_14195	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JAV55_14200	COG5416	Lipopolysaccharide assembly protein A domain
JAV55_14205	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JAV55_14205	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JAV55_14215	COG2244	polysaccharide biosynthetic process
JAV55_14220	COG2323	membrane
JAV55_14230	COG1862	Preprotein translocase
JAV55_14235	COG0343	queuine tRNA-ribosyltransferase activity
JAV55_14240	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JAV55_14250	COG2255	four-way junction helicase activity
JAV55_14255	COG0632	four-way junction helicase activity
JAV55_14265	COG2112	serine threonine protein kinase
JAV55_14275	COG2318	DinB family
JAV55_14280	COG4195	phage-related replication protein
JAV55_14295	COG0217	transcriptional regulatory protein
JAV55_14305	COG1388	LysM domain
JAV55_14310	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JAV55_14315	COG0157	Belongs to the NadC ModD family
JAV55_14320	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JAV55_14325	COG1104	cysteine desulfurase activity
JAV55_14330	COG1827	regulation of RNA biosynthetic process
JAV55_14335	COG0077	Prephenate dehydratase
JAV55_14340	COG4492	Belongs to the UPF0735 family
JAV55_14345	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JAV55_14350	COG3290	protein histidine kinase activity
JAV55_14355	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JAV55_14360	COG2868	ribosomal protein
JAV55_14365	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JAV55_14370	COG1994	Peptidase M50
JAV55_14375	COG0739	heme binding
JAV55_14380	COG3832	glyoxalase III activity
JAV55_14385	COG0640	Transcriptional regulator
JAV55_14390	COG2894	cell division
JAV55_14395	COG0850	regulation of cytokinetic process
JAV55_14400	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
JAV55_14410	COG1077	Cell shape determining protein MreB Mrl
JAV55_14415	COG2003	Belongs to the UPF0758 family
JAV55_14420	COG0424	maF-like protein
JAV55_14430	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JAV55_14435	COG0285	dihydrofolate synthase activity
JAV55_14440	COG0525	valine-tRNA ligase activity
JAV55_14450	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JAV55_14455	COG1388	LysM domain
JAV55_14460	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JAV55_14465	COG0113	porphobilinogen synthase activity
JAV55_14470	COG1587	Uroporphyrinogen-III synthase
JAV55_14475	COG0181	hydroxymethylbilane synthase activity
JAV55_14480	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JAV55_14485	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JAV55_14495	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JAV55_14500	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JAV55_14505	COG0470	DNA polymerase III
JAV55_14505	COG1067	ATP-dependent peptidase activity
JAV55_14510	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JAV55_14515	COG0544	peptidyl-prolyl cis-trans isomerase activity
JAV55_14520	COG1477	protein flavinylation
JAV55_14520	COG0457	Tetratricopeptide repeat
JAV55_14525	COG0066	3-isopropylmalate dehydratase activity
JAV55_14530	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JAV55_14535	COG0473	3-isopropylmalate dehydrogenase activity
JAV55_14540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JAV55_14545	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JAV55_14550	COG0440	acetolactate synthase activity
JAV55_14555	COG0028	Belongs to the TPP enzyme family
JAV55_14560	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JAV55_14570	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JAV55_14625	COG5444	nuclease activity
JAV55_14630	COG0457	Tetratricopeptide repeat
JAV55_14655	COG0622	Phosphoesterase
JAV55_14660	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JAV55_14665	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JAV55_14670	COG5401	PFAM Sporulation and spore germination
JAV55_14675	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JAV55_14680	COG1846	Transcriptional regulator
JAV55_14685	COG2197	response regulator
JAV55_14690	COG4221	oxidoreductase activity
JAV55_14695	COG0824	Thioesterase
JAV55_14700	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JAV55_14705	COG1053	succinate dehydrogenase
JAV55_14710	COG2009	succinate dehydrogenase
JAV55_14715	COG1719	4-vinyl reductase, 4VR
JAV55_14720	COG0527	aspartate kinase activity
JAV55_14725	COG0322	excinuclease ABC activity
JAV55_14730	COG3118	belongs to the thioredoxin family
JAV55_14735	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JAV55_14740	COG2086	electron transfer activity
JAV55_14745	COG1024	Enoyl-CoA hydratase
JAV55_14750	COG1309	transcriptional regulator
JAV55_14755	COG0318	PFAM AMP-dependent synthetase and ligase
JAV55_14760	COG3766	membrane
JAV55_14765	COG1193	negative regulation of DNA recombination
JAV55_14770	COG1796	DNA polymerase
JAV55_14770	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JAV55_14775	COG1286	toxin biosynthetic process
JAV55_14780	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JAV55_14785	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JAV55_14805	COG1137	ATPase activity
JAV55_14820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JAV55_14820	COG0072	phenylalanine-tRNA ligase activity
JAV55_14825	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JAV55_14830	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JAV55_14840	COG1966	Carbon starvation protein
JAV55_14850	COG0395	ABC-type sugar transport system, permease component
JAV55_14855	COG1175	transmembrane transport
JAV55_14860	COG1653	transport
JAV55_14865	COG0371	Dehydrogenase
JAV55_14870	COG0235	Class ii aldolase
JAV55_14875	COG1069	ribulokinase activity
JAV55_14880	COG2160	L-arabinose isomerase activity
JAV55_14885	COG3507	Belongs to the glycosyl hydrolase 43 family
JAV55_14890	COG1363	Peptidase, m42
JAV55_14900	COG3326	Membrane
JAV55_14905	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JAV55_14910	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JAV55_14915	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JAV55_14920	COG1346	cytolysis
JAV55_14930	COG3540	Alkaline phosphatase
JAV55_14935	COG3279	Response regulator of the LytR AlgR family
JAV55_14940	COG3275	phosphorelay sensor kinase activity
JAV55_14950	COG1011	Hydrolase
JAV55_14955	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JAV55_14965	COG0398	Pfam SNARE associated Golgi protein
JAV55_14970	COG1484	DNA-dependent DNA replication
JAV55_14975	COG3611	Membrane attachment protein
JAV55_14980	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JAV55_14990	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JAV55_14995	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JAV55_15000	COG3866	Pectate lyase
JAV55_15005	COG0237	dephospho-CoA kinase activity
JAV55_15010	COG1971	Probably functions as a manganese efflux pump
JAV55_15015	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JAV55_15020	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JAV55_15020	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JAV55_15025	COG5002	protein histidine kinase activity
JAV55_15030	COG0745	RESPONSE REGULATOR receiver
JAV55_15035	COG0039	L-malate dehydrogenase activity
JAV55_15040	COG0538	isocitrate dehydrogenase activity
JAV55_15045	COG0372	Belongs to the citrate synthase family
JAV55_15050	COG2707	UPF0756 membrane protein
JAV55_15055	COG0628	permease
JAV55_15060	COG3030	protein affecting phage T7 exclusion by the F plasmid
JAV55_15070	COG0205	6-phosphofructokinase activity
JAV55_15075	COG0825	malonyl-CoA metabolic process
JAV55_15080	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JAV55_15085	COG0281	malic enzyme
JAV55_15090	COG0587	DNA-directed DNA polymerase activity
JAV55_15110	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JAV55_15120	COG4109	DRTGG domain
JAV55_15125	COG1695	Transcriptional regulator
JAV55_15130	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JAV55_15135	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_15145	COG0165	Argininosuccinate lyase
JAV55_15150	COG0137	argininosuccinate synthase activity
JAV55_15155	COG0521	Mo-molybdopterin cofactor biosynthetic process
JAV55_15160	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JAV55_15165	COG0827	DNA restriction-modification system
JAV55_15170	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JAV55_15175	COG3874	Sporulation protein YtfJ
JAV55_15185	COG1714	RDD family
JAV55_15190	COG0616	signal peptide processing
JAV55_15195	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JAV55_15200	COG1566	PFAM secretion protein HlyD family protein
JAV55_15205	COG0477	Major facilitator Superfamily
JAV55_15215	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JAV55_15225	COG0301	tRNA thio-modification
JAV55_15230	COG1104	cysteine desulfurase activity
JAV55_15235	COG1114	Component of the transport system for branched-chain amino acids
JAV55_15240	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JAV55_15245	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JAV55_15250	COG1309	transcriptional regulator
JAV55_15255	COG1956	GAF domain-containing protein
JAV55_15260	COG2203	Gaf domain
JAV55_15260	COG2199	diguanylate cyclase activity
JAV55_15265	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JAV55_15275	COG3152	Membrane
JAV55_15280	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JAV55_15285	COG1522	sequence-specific DNA binding
JAV55_15295	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JAV55_15300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JAV55_15305	COG0454	-acetyltransferase
JAV55_15310	COG0517	IMP dehydrogenase activity
JAV55_15315	COG0123	including yeast histone deacetylase and acetoin utilization protein
JAV55_15320	COG1360	Flagellar Motor Protein
JAV55_15325	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JAV55_15330	COG1609	Transcriptional regulator
JAV55_15335	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JAV55_15335	COG1605	Chorismate mutase
JAV55_15345	COG3118	belongs to the thioredoxin family
JAV55_15350	COG4980	gas vesicle protein
JAV55_15355	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JAV55_15360	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JAV55_15365	COG1674	ftsk spoiiie
JAV55_15370	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JAV55_15375	COG4848	Belongs to the UPF0354 family
JAV55_15380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JAV55_15390	COG1363	Peptidase, m42
JAV55_15395	COG5584	Small secreted protein
JAV55_15400	COG0281	malic enzyme
JAV55_15405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JAV55_15410	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JAV55_15420	COG0510	thiamine kinase activity
JAV55_15425	COG1523	belongs to the glycosyl hydrolase 13 family
JAV55_15430	COG1597	lipid kinase activity
JAV55_15440	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JAV55_15445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JAV55_15460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JAV55_15465	COG2252	PERMEase
JAV55_15470	COG1349	DNA-binding transcription factor activity
JAV55_15475	COG1187	pseudouridine synthase activity
JAV55_15480	COG2244	polysaccharide biosynthetic process
JAV55_15485	COG2081	HI0933 family
JAV55_15490	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JAV55_15500	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JAV55_15515	COG5578	integral membrane protein
JAV55_15520	COG0673	inositol 2-dehydrogenase activity
JAV55_15525	COG1653	transport
JAV55_15530	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
JAV55_15535	COG4209	transmembrane transport
JAV55_15540	COG2207	Transcriptional regulator
JAV55_15545	COG1653	transport
JAV55_15550	COG0395	ABC-type sugar transport system, permease component
JAV55_15555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JAV55_15560	COG1073	alpha beta
JAV55_15570	COG0583	DNA-binding transcription factor activity
JAV55_15575	COG0346	lactoylglutathione lyase activity
JAV55_15580	COG0495	leucyl-tRNA aminoacylation
JAV55_15590	COG2814	Major facilitator Superfamily
JAV55_15600	COG2433	Pfam Transposase IS66
JAV55_15605	COG0577	efflux transmembrane transporter activity
JAV55_15610	COG1136	(ABC) transporter
JAV55_15620	COG1131	(ABC) transporter
JAV55_15625	COG1725	Transcriptional regulator
JAV55_15635	COG1242	4 iron, 4 sulfur cluster binding
JAV55_15640	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JAV55_15645	COG1301	dicarboxylic acid transport
JAV55_15655	COG2267	carboxylic ester hydrolase activity
JAV55_15660	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JAV55_15665	COG0671	phosphoesterase, PA-phosphatase related
JAV55_15670	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JAV55_15670	COG0438	transferase activity, transferring glycosyl groups
JAV55_15675	COG0367	asparagine synthase
JAV55_15680	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JAV55_15685	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JAV55_15700	COG1506	peptidase
JAV55_15705	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JAV55_15710	COG1116	anion transmembrane transporter activity
JAV55_15715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JAV55_15720	COG0494	nUDIX hydrolase
JAV55_15730	COG4824	toxin secretion phage lysis holin
JAV55_15735	COG0783	Belongs to the Dps family
JAV55_15750	COG1854	S-ribosylhomocysteine lyase activity
JAV55_15755	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JAV55_15760	COG0288	reversible hydration of carbon dioxide
JAV55_15765	COG0523	cobalamin synthesis protein
JAV55_15770	COG0803	Belongs to the bacterial solute-binding protein 9 family
JAV55_15775	COG0254	rRNA binding
JAV55_15780	COG1271	oxidase subunit
JAV55_15785	COG1294	oxidase, subunit
JAV55_15800	COG4948	Mandelate Racemase Muconate Lactonizing
JAV55_15805	COG0318	PFAM AMP-dependent synthetase and ligase
JAV55_15810	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JAV55_15815	COG0596	Alpha beta hydrolase
JAV55_15820	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JAV55_15825	COG1169	isochorismate synthase
JAV55_15830	COG1575	Belongs to the MenA family. Type 1 subfamily
JAV55_15835	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JAV55_15840	COG0058	SHG alpha-glucan phosphorylase activity
JAV55_15845	COG0297	glycogen (starch) synthase activity
JAV55_15850	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JAV55_15855	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JAV55_15985	COG1609	Transcriptional regulator
JAV55_15990	COG3859	Proton-coupled thiamine transporter YuaJ
JAV55_15995	COG3764	Sortase (surface protein transpeptidase)
JAV55_16010	COG0457	Tetratricopeptide repeat
JAV55_16015	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JAV55_16020	COG0569	domain protein
JAV55_16025	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JAV55_16035	COG2318	DinB family
JAV55_16045	COG1454	alcohol dehydrogenase
JAV55_16050	COG1012	belongs to the aldehyde dehydrogenase family
JAV55_16055	COG1510	regulation of RNA biosynthetic process
JAV55_16065	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JAV55_16070	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JAV55_16075	COG2140	Oxalate decarboxylase
JAV55_16110	COG1397	ADP-ribosylglycohydrolase
JAV55_16145	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
JAV55_16160	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JAV55_16165	COG0726	polysaccharide deacetylase
JAV55_16170	COG1408	metallophosphoesterase
JAV55_16175	COG1968	undecaprenyl-diphosphatase activity
JAV55_16180	COG0628	permease
JAV55_16185	COG0673	inositol 2-dehydrogenase activity
JAV55_16190	COG0693	protein deglycase activity
JAV55_16195	COG0840	transmembrane signaling receptor activity
JAV55_16200	COG0840	transmembrane signaling receptor activity
JAV55_16205	COG0840	transmembrane signaling receptor activity
JAV55_16215	COG2070	2-Nitropropane dioxygenase
JAV55_16220	COG0432	Pfam Uncharacterised protein family UPF0047
JAV55_16225	COG0366	Alpha amylase catalytic
JAV55_16240	COG5297	Belongs to the glycosyl hydrolase family 6
JAV55_16245	COG1253	flavin adenine dinucleotide binding
JAV55_16250	COG2738	Putative neutral zinc metallopeptidase
JAV55_16265	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JAV55_16280	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
JAV55_16290	COG0166	Belongs to the GPI family
JAV55_16295	COG1979	alcohol dehydrogenase
JAV55_16300	COG2155	Conserved Protein
JAV55_16305	COG1098	S1 RNA binding domain
JAV55_16310	COG0436	Aminotransferase
JAV55_16315	COG1522	sequence-specific DNA binding
JAV55_16320	COG2267	carboxylic ester hydrolase activity
JAV55_16335	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JAV55_16350	COG5018	Exonuclease
JAV55_16355	COG2814	Major facilitator Superfamily
JAV55_16360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JAV55_16365	COG3011	Protein conserved in bacteria
JAV55_16375	COG3290	protein histidine kinase activity
JAV55_16380	COG4565	transcriptional regulatory protein
JAV55_16390	COG1183	phosphatidylcholine synthase activity
JAV55_16395	COG0586	Pfam SNARE associated Golgi protein
JAV55_16400	COG0688	phosphatidylethanolamine metabolic process
JAV55_16405	COG3493	citrate carrier protein
JAV55_16415	COG2111	Na H antiporter
JAV55_16415	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JAV55_16420	COG2111	Na H antiporter
JAV55_16425	COG1006	Multisubunit Na H antiporter MnhC subunit
JAV55_16430	COG0651	ATP synthesis coupled electron transport
JAV55_16435	COG1863	multisubunit Na H antiporter MnhE subunit
JAV55_16440	COG2212	antiporter activity
JAV55_16445	COG1320	monovalent cation:proton antiporter activity
JAV55_16450	COG2050	protein possibly involved in aromatic compounds catabolism
JAV55_16455	COG2197	response regulator
JAV55_16460	COG4585	Histidine kinase
JAV55_16470	COG0142	geranyltranstransferase activity
JAV55_16485	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JAV55_16490	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JAV55_16495	COG1335	isochorismatase
JAV55_16500	COG5506	Protein of unknown function (DUF1694)
JAV55_16515	COG0628	permease
JAV55_16520	COG1959	2 iron, 2 sulfur cluster binding
JAV55_16525	COG0657	acetylesterase activity
JAV55_16535	COG1418	mRNA catabolic process
JAV55_16540	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_16550	COG1511	domain protein
JAV55_16555	COG0433	COG0433 Predicted ATPase
JAV55_16555	COG1674	ftsk spoiiie
JAV55_16560	COG4499	WXG100 protein secretion system (Wss), protein YukC
JAV55_16565	COG5417	Belongs to the EsaB family
JAV55_16570	COG4842	Belongs to the WXG100 family
JAV55_16575	COG1115	amino acid carrier protein
JAV55_16580	COG2508	Transcriptional regulator
JAV55_16580	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JAV55_16585	COG0686	Belongs to the AlaDH PNT family
JAV55_16595	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JAV55_16600	COG1268	BioY protein
JAV55_16605	COG2056	Na+-H+ antiporter family
JAV55_16610	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JAV55_16615	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
JAV55_16620	COG3584	3D domain protein
JAV55_16635	COG1252	NADH dehydrogenase
JAV55_16640	COG0492	ferredoxin-NADP+ reductase activity
JAV55_16655	COG0456	acetyltransferase
JAV55_16660	COG0316	Belongs to the HesB IscA family
JAV55_16665	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JAV55_16670	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JAV55_16675	COG4844	belongs to the
JAV55_16680	COG1252	NADH dehydrogenase
JAV55_16685	COG5646	InterPro IPR014922
JAV55_16695	COG0457	Tetratricopeptide repeat
JAV55_16700	COG3479	Phenolic acid decarboxylase
JAV55_16710	COG4837	Protein of unknown function (DUF1462)
JAV55_16715	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JAV55_16720	COG4946	Tricorn protease homolog
JAV55_16720	COG1506	peptidase
JAV55_16720	COG0823	Involved in the tonB-independent uptake of proteins
JAV55_16725	COG0083	homoserine kinase activity
JAV55_16730	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JAV55_16735	COG0460	homoserine dehydrogenase
JAV55_16745	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JAV55_16750	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JAV55_16755	COG0647	UMP catabolic process
JAV55_16760	COG2445	Protein of unknown function DUF86
JAV55_16765	COG4470	Protein conserved in bacteria
JAV55_16780	COG0739	heme binding
JAV55_16790	COG0733	neurotransmitter:sodium symporter activity
JAV55_16800	COG3377	Domain of unknown function (DUF1805)
JAV55_16805	COG0737	Belongs to the 5'-nucleotidase family
JAV55_16810	COG0730	response to heat
JAV55_16815	COG1801	Protein of unknown function DUF72
JAV55_16825	COG3226	Transcriptional regulator
JAV55_16835	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JAV55_16840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JAV55_16845	COG2508	Transcriptional regulator
JAV55_16850	COG2814	Major facilitator Superfamily
JAV55_16855	COG1288	antiporter activity
JAV55_16860	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JAV55_16865	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JAV55_16870	COG2356	endonuclease I
JAV55_16880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JAV55_16895	COG0457	Tetratricopeptide repeat
JAV55_16900	COG0719	Fe-S assembly protein
JAV55_16905	COG0822	iron-sulfur transferase activity
JAV55_16910	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JAV55_16915	COG0719	Fe-S assembly protein
JAV55_16920	COG0396	ATPase activity
JAV55_16930	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JAV55_16935	COG1464	Belongs to the NlpA lipoprotein family
JAV55_16940	COG2011	ABC-type metal ion transport system permease component
JAV55_16945	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JAV55_16955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JAV55_16960	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JAV55_16970	COG0509	glycine decarboxylation via glycine cleavage system
JAV55_16975	COG1393	Belongs to the ArsC family
JAV55_16980	COG1960	acyl-CoA dehydrogenase activity
JAV55_16985	COG0183	Belongs to the thiolase family
JAV55_16990	COG1250	3-hydroxyacyl-CoA dehydrogenase
JAV55_16990	COG1024	Enoyl-CoA hydratase
JAV55_17005	COG5577	PFAM Coat F domain
JAV55_17020	COG1120	ATPase activity
JAV55_17025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JAV55_17030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JAV55_17035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JAV55_17050	COG1686	Belongs to the peptidase S11 family
JAV55_17055	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_17060	COG0783	Belongs to the Dps family
JAV55_17065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JAV55_17070	COG0745	RESPONSE REGULATOR receiver
JAV55_17075	COG2770	Histidine kinase
JAV55_17075	COG2205	protein histidine kinase activity
JAV55_17085	COG1309	transcriptional regulator
JAV55_17090	COG0114	fumarate hydratase activity
JAV55_17100	COG0697	spore germination
JAV55_17105	COG0814	amino acid
JAV55_17120	COG2197	response regulator
JAV55_17125	COG4585	Histidine kinase
JAV55_17130	COG4758	membrane
JAV55_17140	COG1842	Phage shock protein A
JAV55_17145	COG4758	membrane
JAV55_17150	COG4677	pectinesterase activity
JAV55_17155	COG2096	Adenosyltransferase
JAV55_17160	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_17175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JAV55_17180	COG1120	ATPase activity
JAV55_17185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JAV55_17190	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JAV55_17195	COG1802	Transcriptional regulator
JAV55_17200	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_17205	COG2258	MOSC domain
JAV55_17210	COG0583	DNA-binding transcription factor activity
JAV55_17220	COG2721	sulfolactate sulfo-lyase activity
JAV55_17225	COG0246	Mannitol dehydrogenase
JAV55_17230	COG1609	Transcriptional regulator
JAV55_17235	COG2211	Major facilitator Superfamily
JAV55_17240	COG1904	glucuronate isomerase
JAV55_17245	COG2205	protein histidine kinase activity
JAV55_17250	COG0745	RESPONSE REGULATOR receiver
JAV55_17255	COG1120	ATPase activity
JAV55_17260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JAV55_17265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JAV55_17270	COG0531	amino acid
JAV55_17280	COG1988	membrane-bound metal-dependent
JAV55_17285	COG1368	sulfuric ester hydrolase activity
JAV55_17290	COG2814	Major facilitator Superfamily
JAV55_17295	COG0656	L-ascorbic acid biosynthetic process
JAV55_17300	COG1940	carbohydrate kinase activity
JAV55_17305	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JAV55_17315	COG3973	AAA domain
JAV55_17320	COG2860	membrane
JAV55_17325	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JAV55_17325	COG0456	acetyltransferase
JAV55_17330	COG0456	acetyltransferase
JAV55_17335	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
JAV55_17340	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JAV55_17345	COG2217	Heavy metal translocating P-type atpase
JAV55_17355	COG1175	transmembrane transport
JAV55_17360	COG0395	ABC-type sugar transport system, permease component
JAV55_17365	COG1501	Belongs to the glycosyl hydrolase 31 family
JAV55_17370	COG1472	Belongs to the glycosyl hydrolase 3 family
JAV55_17375	COG1121	(ABC) transporter
JAV55_17380	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JAV55_17385	COG0803	Belongs to the bacterial solute-binding protein 9 family
JAV55_17400	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JAV55_17400	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
JAV55_17405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JAV55_17405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JAV55_17405	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JAV55_17425	COG2217	Heavy metal translocating P-type atpase
JAV55_17430	COG2608	mercury ion transmembrane transporter activity
JAV55_17435	COG1937	Protein conserved in bacteria
JAV55_17440	COG0693	protein deglycase activity
JAV55_17445	COG1349	DNA-binding transcription factor activity
JAV55_17450	COG1070	Carbohydrate kinase
JAV55_17455	COG4952	isomerase
JAV55_17465	COG3347	Dehydrogenase
JAV55_17465	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_17470	COG2814	Major facilitator Superfamily
JAV55_17475	COG2814	Major facilitator Superfamily
JAV55_17485	COG2124	cytochrome p450
JAV55_17495	COG1846	Transcriptional regulator
JAV55_17505	COG0673	inositol 2-dehydrogenase activity
JAV55_17510	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JAV55_17515	COG1054	Belongs to the UPF0176 family
JAV55_17525	COG1191	sigma factor activity
JAV55_17535	COG2140	Oxalate decarboxylase
JAV55_17565	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JAV55_17655	COG1705	Flagellar rod assembly protein muramidase FlgJ
JAV55_17665	COG3953	SLT domain
JAV55_17665	COG5280	Phage tail tape measure protein TP901
JAV55_17725	COG1802	Transcriptional regulator
JAV55_17725	COG4626	Terminase
JAV55_17870	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JAV55_17875	COG0557	exoribonuclease II activity
JAV55_17880	COG1647	Serine aminopeptidase, S33
JAV55_17885	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JAV55_17890	COG2002	toxin-antitoxin pair type II binding
JAV55_17895	COG1476	TRANSCRIPTIONal
JAV55_17900	COG1396	sequence-specific DNA binding
JAV55_17905	COG1396	sequence-specific DNA binding
JAV55_17910	COG1174	glycine betaine transport
JAV55_17915	COG1732	Glycine betaine
JAV55_17920	COG1174	glycine betaine transport
JAV55_17925	COG1125	glycine betaine transport
JAV55_17925	COG0517	IMP dehydrogenase activity
JAV55_17930	COG1510	regulation of RNA biosynthetic process
JAV55_17935	COG2095	MarC family integral membrane protein
JAV55_17950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JAV55_17960	COG0693	protein deglycase activity
JAV55_17965	COG0148	phosphopyruvate hydratase activity
JAV55_17970	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JAV55_17975	COG0149	triose-phosphate isomerase activity
JAV55_17980	COG0126	phosphoglycerate kinase activity
JAV55_17985	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JAV55_17990	COG2390	Transcriptional regulator
JAV55_17995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JAV55_18000	COG1113	amino acid transport
JAV55_18020	COG1556	Lactate utilization protein
JAV55_18025	COG1139	Iron-sulfur cluster binding protein
JAV55_18030	COG0247	lactate metabolic process
JAV55_18035	COG2186	Transcriptional regulator
JAV55_18040	COG1620	l-lactate permease
JAV55_18045	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
JAV55_18055	COG5039	Polysaccharide pyruvyl transferase
JAV55_18060	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JAV55_18065	COG0110	maltose O-acetyltransferase activity
JAV55_18070	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JAV55_18075	COG2244	polysaccharide biosynthetic process
JAV55_18080	COG1216	Glycosyl transferase, family 2
JAV55_18085	COG5039	Polysaccharide pyruvyl transferase
JAV55_18090	COG1216	Glycosyl transferase, family 2
JAV55_18100	COG0438	transferase activity, transferring glycosyl groups
JAV55_18105	COG1215	transferase activity, transferring glycosyl groups
JAV55_18110	COG0438	transferase activity, transferring glycosyl groups
JAV55_18115	COG1086	Polysaccharide biosynthesis protein
JAV55_18120	COG0489	protein tyrosine kinase activity
JAV55_18125	COG3944	biosynthesis protein
JAV55_18130	COG1396	sequence-specific DNA binding
JAV55_18140	COG2249	NAD(P)H dehydrogenase (quinone) activity
JAV55_18145	COG2271	Major facilitator Superfamily
JAV55_18155	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
JAV55_18170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JAV55_18180	COG1733	regulation of RNA biosynthetic process
JAV55_18185	COG1902	pentaerythritol trinitrate reductase activity
JAV55_18190	COG1621	beta-fructofuranosidase activity
JAV55_18195	COG1621	beta-fructofuranosidase activity
JAV55_18210	COG0740	serine-type endopeptidase activity
JAV55_18215	COG1611	Belongs to the LOG family
JAV55_18220	COG1694	Mazg nucleotide pyrophosphohydrolase
JAV55_18225	COG1078	dGTPase activity
JAV55_18230	COG0659	secondary active sulfate transmembrane transporter activity
JAV55_18235	COG0288	reversible hydration of carbon dioxide
JAV55_18240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JAV55_18245	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JAV55_18250	COG0640	Transcriptional regulator
JAV55_18260	COG2732	(Barnase) inhibitor
JAV55_18265	COG2162	N-hydroxyarylamine O-acetyltransferase activity
JAV55_18270	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JAV55_18275	COG1481	regulation of sporulation
JAV55_18280	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JAV55_18285	COG1660	Displays ATPase and GTPase activities
JAV55_18290	COG1051	belongs to the nudix hydrolase family
JAV55_18295	COG0492	ferredoxin-NADP+ reductase activity
JAV55_18300	COG0457	Tetratricopeptide repeat
JAV55_18305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JAV55_18310	COG0140	phosphoribosyl-ATP diphosphatase activity
JAV55_18310	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JAV55_18315	COG0107	imidazoleglycerol-phosphate synthase activity
JAV55_18320	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JAV55_18325	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JAV55_18330	COG0131	Imidazoleglycerol-phosphate dehydratase
JAV55_18335	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JAV55_18340	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JAV55_18345	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JAV55_18350	COG4990	cell redox homeostasis
JAV55_18355	COG5297	Belongs to the glycosyl hydrolase family 6
JAV55_18360	COG0110	maltose O-acetyltransferase activity
JAV55_18365	COG0546	phosphoglycolate phosphatase activity
JAV55_18370	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
JAV55_18375	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JAV55_18380	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JAV55_18385	COG1846	Transcriptional regulator
JAV55_18390	COG2814	Major facilitator Superfamily
JAV55_18395	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JAV55_18400	COG1950	PFAM Membrane protein of
JAV55_18405	COG1983	PspC domain protein
JAV55_18410	COG3595	metallopeptidase activity
JAV55_18430	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JAV55_18435	COG0556	nucleotide-excision repair
JAV55_18440	COG4897	Protein conserved in bacteria
JAV55_18450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JAV55_18460	COG3409	Peptidoglycan-binding domain 1 protein
JAV55_18460	COG0793	Belongs to the peptidase S41A family
JAV55_18465	COG0473	3-isopropylmalate dehydrogenase activity
JAV55_18470	COG0791	NLP P60 protein
JAV55_18470	COG3883	PFAM NLP P60 protein
JAV55_18475	COG2177	Part of the ABC transporter FtsEX involved in
JAV55_18480	COG2884	Cell division ATP-binding protein ftsE
JAV55_18485	COG2010	Cytochrome c
JAV55_18490	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JAV55_18500	COG0653	protein targeting
JAV55_18505	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JAV55_18520	COG1516	flagellar protein fliS
JAV55_18525	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JAV55_18530	COG1334	flagellar protein FlaG
JAV55_18535	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JAV55_18540	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
JAV55_18545	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
JAV55_18555	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JAV55_18560	COG1256	bacterial-type flagellum assembly
JAV55_18560	COG4786	Flagellar basal body rod
JAV55_18565	COG3418	PFAM FlgN family protein
JAV55_18570	COG2747	anti-sigma28 factor FlgM
JAV55_18580	COG1040	competence protein
JAV55_18590	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JAV55_18595	COG1307	EDD domain protein, DegV family
JAV55_18600	COG2197	response regulator
JAV55_18605	COG4585	Histidine kinase
JAV55_18610	COG1739	Uncharacterized protein family UPF0029
JAV55_18615	COG1316	TRANSCRIPTIONal
JAV55_18625	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JAV55_18630	COG0438	transferase activity, transferring glycosyl groups
JAV55_18635	COG1215	transferase activity, transferring glycosyl groups
JAV55_18640	COG3206	protein involved in exopolysaccharide biosynthesis
JAV55_18645	COG3307	-O-antigen
JAV55_18650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JAV55_18655	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JAV55_18660	COG0297	glycogen (starch) synthase activity
JAV55_18660	COG0438	transferase activity, transferring glycosyl groups
JAV55_18665	COG2244	polysaccharide biosynthetic process
JAV55_18675	COG0860	N-Acetylmuramoyl-L-alanine amidase
JAV55_18675	COG2247	cell wall binding repeat
JAV55_18680	COG2385	sporulation resulting in formation of a cellular spore
JAV55_18680	COG2247	cell wall binding repeat
JAV55_18690	COG1316	TRANSCRIPTIONal
JAV55_18695	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JAV55_18705	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JAV55_18710	COG1134	teichoic acid transport
JAV55_18715	COG1682	transport, permease protein
JAV55_18720	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JAV55_18720	COG0463	Glycosyl transferase, family 2
JAV55_18725	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JAV55_18730	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JAV55_18735	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
JAV55_18740	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JAV55_18745	COG4193	domain, Protein
JAV55_18750	COG1482	cell wall glycoprotein biosynthetic process
JAV55_18770	COG0800	Aldolase
JAV55_18775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JAV55_18780	COG1609	Transcriptional regulator
JAV55_18785	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
JAV55_18790	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_18795	COG1063	alcohol dehydrogenase
JAV55_18805	COG2814	Major facilitator Superfamily
JAV55_18810	COG1316	TRANSCRIPTIONal
JAV55_18815	COG0561	phosphatase activity
JAV55_18820	COG0791	NLP P60 protein
JAV55_18830	COG2843	Capsule synthesis protein
JAV55_18840	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JAV55_18845	COG1609	Transcriptional regulator
JAV55_18850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JAV55_18855	COG1869	D-ribose catabolic process
JAV55_18860	COG1129	ABC transporter
JAV55_18865	COG1172	Belongs to the binding-protein-dependent transport system permease family
JAV55_18870	COG1879	ABC-type sugar transport system periplasmic component
JAV55_18875	COG3527	Alpha-acetolactate decarboxylase
JAV55_18880	COG0028	Belongs to the TPP enzyme family
JAV55_18885	COG0583	DNA-binding transcription factor activity
JAV55_18890	COG0405	Gamma-glutamyltransferase
JAV55_18895	COG1522	sequence-specific DNA binding
JAV55_18900	COG2059	Chromate
JAV55_18905	COG2059	Chromate
JAV55_18910	COG4464	protein tyrosine phosphatase activity
JAV55_18915	COG3944	biosynthesis protein
JAV55_18925	COG4715	Zinc finger, swim domain protein
JAV55_18930	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JAV55_18935	COG0561	phosphatase activity
JAV55_18940	COG1349	DNA-binding transcription factor activity
JAV55_18950	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_18960	COG3732	PTS system glucitol sorbitol-specific
JAV55_18980	COG0629	single-stranded DNA binding
JAV55_18995	COG1970	mechanosensitive ion channel activity
JAV55_19000	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JAV55_19005	COG4786	Flagellar basal body rod
JAV55_19010	COG4786	Flagellar basal body rod
JAV55_19015	COG1077	Cell shape determining protein MreB Mrl
JAV55_19020	COG1609	Transcriptional regulator
JAV55_19025	COG1846	Transcriptional regulator
JAV55_19030	COG2814	Major facilitator Superfamily
JAV55_19035	COG0671	phosphoesterase, PA-phosphatase related
JAV55_19040	COG1227	inorganic diphosphatase activity
JAV55_19045	COG3546	catalase activity
JAV55_19050	COG3361	conserved protein (COG2071)
JAV55_19055	COG0517	IMP dehydrogenase activity
JAV55_19060	COG0598	Magnesium transport protein CorA
JAV55_19065	COG1253	flavin adenine dinucleotide binding
JAV55_19070	COG0004	ammonium transporteR
JAV55_19075	COG0347	Belongs to the P(II) protein family
JAV55_19080	COG0740	serine-type endopeptidase activity
JAV55_19090	COG0739	heme binding
JAV55_19095	COG1247	-acetyltransferase
JAV55_19105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JAV55_19115	COG0477	Major facilitator Superfamily
JAV55_19120	COG3251	PFAM MbtH domain protein
JAV55_19125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JAV55_19130	COG1535	isochorismatase
JAV55_19130	COG3433	isochorismatase activity
JAV55_19135	COG1021	2,3-dihydroxybenzoate-AMP ligase
JAV55_19140	COG1169	isochorismate synthase
JAV55_19145	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_19150	COG2819	hydrolase of the alpha beta superfamily
JAV55_19155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JAV55_19160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JAV55_19165	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JAV55_19170	COG2207	Transcriptional regulator
JAV55_19170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JAV55_19180	COG2910	NAD(P)H-binding
JAV55_19185	COG1959	2 iron, 2 sulfur cluster binding
JAV55_19195	COG1994	Peptidase M50
JAV55_19200	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JAV55_19205	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JAV55_19210	COG2223	nitrite transmembrane transporter activity
JAV55_19215	COG0243	molybdopterin cofactor binding
JAV55_19220	COG2304	oxidoreductase activity
JAV55_19225	COG2304	oxidoreductase activity
JAV55_19230	COG2385	sporulation resulting in formation of a cellular spore
JAV55_19235	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JAV55_19245	COG4836	Membrane
JAV55_19250	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JAV55_19255	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JAV55_19260	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JAV55_19265	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JAV55_19270	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JAV55_19275	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JAV55_19280	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JAV55_19295	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JAV55_19300	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JAV55_19305	COG4475	Protein of unknown function (DUF436)
JAV55_19310	COG0698	ribose 5-phosphate isomerase
JAV55_19315	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JAV55_19320	COG1971	Probably functions as a manganese efflux pump
JAV55_19325	COG0009	L-threonylcarbamoyladenylate synthase
JAV55_19330	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JAV55_19340	COG0738	Major facilitator superfamily
JAV55_19345	COG0673	inositol 2-dehydrogenase activity
JAV55_19350	COG0561	phosphatase activity
JAV55_19355	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JAV55_19360	COG1609	Transcriptional regulator
JAV55_19365	COG2890	protein-(glutamine-N5) methyltransferase activity
JAV55_19370	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JAV55_19375	COG0346	lactoylglutathione lyase activity
JAV55_19380	COG0789	Transcriptional regulator
JAV55_19385	COG0679	Auxin Efflux Carrier
JAV55_19390	COG0281	malic enzyme
JAV55_19395	COG1435	thymidine kinase activity
JAV55_19400	COG0254	rRNA binding
JAV55_19405	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JAV55_19410	COG1494	fructose-1,6-bisphosphatase
JAV55_19415	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JAV55_19420	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JAV55_19425	COG0191	fructose-bisphosphate aldolase activity
JAV55_19430	COG2204	response regulator
JAV55_19435	COG4821	SIS domain
JAV55_19440	COG0504	CTP synthase activity
JAV55_19445	COG3343	RNA polymerase activity
JAV55_19455	COG1960	acyl-CoA dehydrogenase activity
JAV55_19460	COG1960	acyl-CoA dehydrogenase activity
JAV55_19465	COG1250	3-hydroxyacyl-CoA dehydrogenase
JAV55_19470	COG0183	Belongs to the thiolase family
JAV55_19475	COG0247	lactate metabolic process
JAV55_19475	COG2181	nitrate reductase activity
JAV55_19480	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JAV55_19490	COG0018	arginyl-trna synthetase
JAV55_19495	COG4506	Protein conserved in bacteria
JAV55_19500	COG0010	Belongs to the arginase family
JAV55_19505	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JAV55_19520	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JAV55_19530	COG1994	Peptidase M50
JAV55_19535	COG1942	4-Oxalocrotonate Tautomerase
JAV55_19545	COG3465	dGTPase activity
JAV55_19550	COG1078	dGTPase activity
JAV55_19555	COG4844	belongs to the
JAV55_19580	COG2814	Major facilitator Superfamily
JAV55_19605	COG1414	Transcriptional regulator
JAV55_19615	COG0280	phosphate acetyltransferase
JAV55_19620	COG3253	May function as heme-dependent peroxidase
JAV55_19630	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JAV55_19650	COG1131	(ABC) transporter
JAV55_19665	COG2363	Small membrane protein
JAV55_19670	COG2233	PERMEase
JAV55_19680	COG1012	belongs to the aldehyde dehydrogenase family
JAV55_19685	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JAV55_19690	COG1216	Glycosyl transferase, family 2
JAV55_19695	COG0351	phosphomethylpyrimidine kinase
JAV55_19705	COG1621	beta-fructofuranosidase activity
JAV55_19710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JAV55_19710	COG1263	PTS System
JAV55_19715	COG3711	transcriptional antiterminator
JAV55_19725	COG1404	Belongs to the peptidase S8 family
JAV55_19735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JAV55_19740	COG0778	Nitroreductase
JAV55_19745	COG1473	amidohydrolase
JAV55_19750	COG0772	Belongs to the SEDS family
JAV55_19755	COG0772	Belongs to the SEDS family
JAV55_19760	COG3314	Sporulation integral membrane protein YlbJ
JAV55_19775	COG0456	acetyltransferase
JAV55_19810	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JAV55_19820	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JAV55_19825	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JAV55_19830	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JAV55_19845	COG3162	membrane
JAV55_19850	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JAV55_19855	COG1070	Carbohydrate kinase
JAV55_19860	COG2115	Belongs to the xylose isomerase family
JAV55_19870	COG0352	thiamine-phosphate diphosphorylase activity
JAV55_19875	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JAV55_19880	COG0583	DNA-binding transcription factor activity
JAV55_19895	COG1380	Effector of murein hydrolase LrgA
JAV55_19900	COG1346	cytolysis
JAV55_19910	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JAV55_19915	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JAV55_19920	COG0346	lactoylglutathione lyase activity
JAV55_19925	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JAV55_19930	COG1442	glycosyl transferase family 8
JAV55_19940	COG4585	Histidine kinase
JAV55_19945	COG2197	response regulator
JAV55_19950	COG2409	Drug exporters of the RND superfamily
JAV55_19955	COG5522	Integral membrane protein (intg_mem_TP0381)
JAV55_19960	COG2271	Major facilitator Superfamily
JAV55_19965	COG4948	Mandelate Racemase Muconate Lactonizing
JAV55_19970	COG0800	Aldolase
JAV55_19975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JAV55_19985	COG2234	aminopeptidase activity
JAV55_19990	COG0477	Major facilitator Superfamily
JAV55_20000	COG2357	RelA SpoT domain protein
JAV55_20015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JAV55_20020	COG1696	Membrane protein involved in D-alanine export
JAV55_20025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JAV55_20030	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JAV55_20035	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JAV55_20040	COG2814	Major facilitator Superfamily
JAV55_20045	COG1486	melibiose metabolic process
JAV55_20050	COG1447	Phosphotransferase system cellobiose-specific component IIA
JAV55_20055	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JAV55_20060	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JAV55_20065	COG3711	transcriptional antiterminator
JAV55_20065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JAV55_20070	COG2094	Belongs to the DNA glycosylase MPG family
JAV55_20080	COG0372	Belongs to the citrate synthase family
JAV55_20085	COG2079	MmgE PrpD family protein
JAV55_20090	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JAV55_20105	COG1132	(ABC) transporter
JAV55_20110	COG2755	lipolytic protein G-D-S-L family
JAV55_20125	COG2814	Major facilitator Superfamily
JAV55_20130	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JAV55_20135	COG1131	(ABC) transporter
JAV55_20155	COG1595	DNA-templated transcription, initiation
JAV55_20160	COG2814	Major facilitator Superfamily
JAV55_20165	COG0753	catalase activity
JAV55_20170	COG0753	catalase activity
JAV55_20175	COG0735	belongs to the Fur family
JAV55_20180	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JAV55_20185	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JAV55_20190	COG1131	(ABC) transporter
JAV55_20205	COG1131	(ABC) transporter
JAV55_20260	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JAV55_20265	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JAV55_20270	COG4988	ABC transporter
JAV55_20275	COG1294	oxidase, subunit
JAV55_20280	COG1271	oxidase subunit
JAV55_20285	COG2116	formate transmembrane transporter activity
JAV55_20295	COG0281	malic enzyme
JAV55_20300	COG1757	Na H antiporter
JAV55_20305	COG1027	Aspartate ammonia-lyase
JAV55_20310	COG0252	asparaginase activity
JAV55_20315	COG1396	sequence-specific DNA binding
JAV55_20320	COG2706	6-phosphogluconolactonase activity
JAV55_20325	COG0745	RESPONSE REGULATOR receiver
JAV55_20330	COG2205	protein histidine kinase activity
JAV55_20335	COG1136	(ABC) transporter
JAV55_20345	COG5294	Protein conserved in bacteria
JAV55_20360	COG0726	polysaccharide deacetylase
JAV55_20365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JAV55_20370	COG1215	transferase activity, transferring glycosyl groups
JAV55_20375	COG3493	citrate carrier protein
JAV55_20380	COG0584	glycerophosphoryl diester phosphodiesterase
JAV55_20395	COG1368	sulfuric ester hydrolase activity
JAV55_20405	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JAV55_20415	COG2235	arginine
JAV55_20420	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JAV55_20430	COG0549	Belongs to the carbamate kinase family
JAV55_20445	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JAV55_20455	COG1595	DNA-templated transcription, initiation
JAV55_20470	COG2195	Cleaves the N-terminal amino acid of tripeptides
JAV55_20475	COG1621	beta-fructofuranosidase activity
JAV55_20480	COG2223	nitrite transmembrane transporter activity
JAV55_20485	COG1609	Transcriptional regulator
JAV55_20500	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JAV55_20505	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JAV55_20510	COG0463	Glycosyl transferase, family 2
JAV55_20515	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JAV55_20540	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JAV55_20545	COG0693	protein deglycase activity
JAV55_20545	COG0753	catalase activity
JAV55_20555	COG2723	6-phospho-beta-galactosidase activity
JAV55_20560	COG1263	PTS System
JAV55_20560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JAV55_20560	COG2190	(PTS) system
JAV55_20570	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JAV55_20575	COG1122	ATPase activity
JAV55_20580	COG4721	ABC-type cobalt transport system, permease component
JAV55_20585	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JAV55_20595	COG2224	Isocitrate lyase
JAV55_20600	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JAV55_20610	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JAV55_20615	COG0577	efflux transmembrane transporter activity
JAV55_20620	COG1136	(ABC) transporter
JAV55_20625	COG2205	protein histidine kinase activity
JAV55_20630	COG0745	RESPONSE REGULATOR receiver
JAV55_20635	COG2723	6-phospho-beta-galactosidase activity
JAV55_20640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JAV55_20640	COG1263	PTS System
JAV55_20640	COG2190	(PTS) system
JAV55_20650	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
JAV55_20665	COG3507	Belongs to the glycosyl hydrolase 43 family
JAV55_20670	COG0513	Belongs to the DEAD box helicase family
JAV55_20700	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
JAV55_20705	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JAV55_20710	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JAV55_20715	COG2390	Transcriptional regulator
JAV55_20725	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
JAV55_20730	COG3706	GGDEF domain
JAV55_20735	COG5298	Protein conserved in bacteria
JAV55_20740	COG1215	transferase activity, transferring glycosyl groups
JAV55_20750	COG3977	Valine--pyruvate aminotransferase
JAV55_20765	COG1181	Belongs to the D-alanine--D-alanine ligase family
JAV55_20775	COG0191	fructose-bisphosphate aldolase activity
JAV55_20780	COG1082	Xylose isomerase domain protein TIM barrel
JAV55_20785	COG1082	Xylose isomerase domain protein TIM barrel
JAV55_20790	COG0673	inositol 2-dehydrogenase activity
JAV55_20795	COG2814	Major facilitator Superfamily
JAV55_20800	COG1082	Xylose isomerase domain protein TIM barrel
JAV55_20805	COG3962	Belongs to the TPP enzyme family
JAV55_20810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JAV55_20815	COG3718	enzyme involved in inositol metabolism
JAV55_20820	COG1012	belongs to the aldehyde dehydrogenase family
JAV55_20825	COG1349	DNA-binding transcription factor activity
JAV55_20830	COG0667	Aldo Keto reductase
JAV55_20835	COG0584	glycerophosphoryl diester phosphodiesterase
JAV55_20840	COG2271	Major facilitator Superfamily
JAV55_20845	COG0326	Molecular chaperone. Has ATPase activity
JAV55_20850	COG0488	(ABC) transporter
JAV55_20855	COG0561	phosphatase activity
JAV55_20875	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JAV55_20905	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
JAV55_20910	COG0577	efflux transmembrane transporter activity
JAV55_20915	COG1136	(ABC) transporter
JAV55_20920	COG2205	protein histidine kinase activity
JAV55_20925	COG0745	RESPONSE REGULATOR receiver
JAV55_20935	COG0840	transmembrane signaling receptor activity
JAV55_20935	COG5278	phosphoserine phosphatase activity
JAV55_20940	COG1115	amino acid carrier protein
JAV55_20945	COG0686	Belongs to the AlaDH PNT family
JAV55_20950	COG3867	Arabinogalactan endo-beta-1,4-galactanase
JAV55_20955	COG1874	Beta-galactosidase
JAV55_20960	COG3833	ABC-type maltose transport systems, permease component
JAV55_20965	COG1175	transmembrane transport
JAV55_20970	COG2182	Extracellular solute-binding protein
JAV55_20975	COG1609	Transcriptional regulator
JAV55_20985	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JAV55_20990	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
JAV55_20995	COG1940	carbohydrate kinase activity
JAV55_21020	COG1454	alcohol dehydrogenase
JAV55_21020	COG1012	belongs to the aldehyde dehydrogenase family
JAV55_21025	COG0450	alkyl hydroperoxide reductase
JAV55_21030	COG3634	alkyl hydroperoxide reductase activity
JAV55_21055	COG1131	(ABC) transporter
JAV55_21060	COG0842	Transport permease protein
JAV55_21065	COG4585	Histidine kinase
JAV55_21070	COG2197	response regulator
JAV55_21100	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JAV55_21115	COG0456	acetyltransferase
JAV55_21130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JAV55_21135	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JAV55_21140	COG4853	Protein conserved in bacteria
JAV55_21145	COG4863	YycH protein
JAV55_21150	COG5002	protein histidine kinase activity
JAV55_21155	COG0745	RESPONSE REGULATOR receiver
JAV55_21180	COG1051	belongs to the nudix hydrolase family
JAV55_21185	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JAV55_21195	COG0305	Participates in initiation and elongation during chromosome replication
JAV55_21210	COG3093	addiction module antidote protein HigA
JAV55_21215	COG2807	transmembrane transport
JAV55_21220	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JAV55_21225	COG0363	glucosamine-6-phosphate deaminase activity
JAV55_21230	COG2188	Transcriptional regulator
JAV55_21235	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JAV55_21240	COG1263	PTS System
JAV55_21240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JAV55_21245	COG0359	binds to the 23S rRNA
JAV55_21250	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
JAV55_21255	COG4241	membrane
JAV55_21265	COG5577	PFAM Coat F domain
JAV55_21270	COG0589	response to stress
JAV55_21275	COG0659	secondary active sulfate transmembrane transporter activity
JAV55_21280	COG2271	Major facilitator Superfamily
JAV55_21285	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JAV55_21290	COG0629	single-stranded DNA binding
JAV55_21295	COG0360	Binds together with S18 to 16S ribosomal RNA
JAV55_21300	COG0012	GTP binding
JAV55_21305	COG4481	Protein conserved in bacteria
JAV55_21310	COG3949	Membrane
JAV55_21320	COG1475	DNA binding
JAV55_21325	COG1192	Involved in chromosome partitioning
JAV55_21330	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JAV55_21340	COG1475	DNA binding
JAV55_21345	COG0357	Ribosomal RNA small subunit methyltransferase G
JAV55_21350	COG0445	tRNA wobble uridine modification
JAV55_21355	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JAV55_21360	COG1847	R3H domain protein
JAV55_21365	COG0706	membrane insertase activity
JAV55_21370	COG0594	ribonuclease P activity