locus-tag	class	description
B34_00002	COG1077	Cell shape determining protein MreB Mrl
B34_00003	COG2002	toxin-antitoxin pair type II binding
B34_00004	COG3852	Histidine kinase
B34_00005	COG0569	domain protein
B34_00006	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
B34_00007	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B34_00009	COG0561	phosphatase activity
B34_00010	COG0242	peptide deformylase activity
B34_00012	COG0497	DNA recombination
B34_00013	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B34_00014	COG0022	dehydrogenase e1 component
B34_00015	COG0508	dehydrogenase complex catalyzes the overall conversion of
B34_00016	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B34_00018	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B34_00020	COG1982	Orn Lys Arg decarboxylase major
B34_00021	COG4476	Belongs to the UPF0223 family
B34_00022	COG4493	Belongs to the UPF0637 family
B34_00024	COG0483	inositol monophosphate 1-phosphatase activity
B34_00028	COG1595	DNA-templated transcription, initiation
B34_00033	COG1846	Transcriptional regulator
B34_00034	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B34_00035	COG4896	Protein conserved in bacteria
B34_00037	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
B34_00038	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B34_00039	COG2066	Belongs to the glutaminase family
B34_00040	COG4838	Belongs to the UPF0358 family
B34_00041	COG0772	Belongs to the SEDS family
B34_00042	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
B34_00043	COG1612	heme a metabolic process
B34_00044	COG0109	protoheme IX farnesyltransferase activity
B34_00045	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B34_00045	COG2010	Cytochrome c
B34_00046	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B34_00047	COG1845	cytochrome c oxidase, subunit III
B34_00048	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B34_00049	COG3336	cytochrome c oxidase
B34_00051	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
B34_00052	COG2340	Cysteine-rich secretory protein family
B34_00055	COG3679	Belongs to the UPF0342 family
B34_00056	COG4471	UPF0298 protein
B34_00058	COG0742	ribosomal rna small subunit methyltransferase
B34_00059	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
B34_00060	COG3314	Sporulation integral membrane protein YlbJ
B34_00061	COG3480	Lon protease (S16) C-terminal proteolytic domain
B34_00062	COG1323	Belongs to the UPF0348 family
B34_00063	COG1399	metal-binding, possibly nucleic acid-binding protein
B34_00064	COG0333	Belongs to the bacterial ribosomal protein bL32 family
B34_00066	COG0454	-acetyltransferase
B34_00067	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B34_00068	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
B34_00069	COG2001	Belongs to the MraZ family
B34_00070	COG0275	rRNA processing
B34_00071	COG4839	cell division protein FtsL
B34_00073	COG0768	penicillin binding
B34_00075	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B34_00076	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B34_00077	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B34_00078	COG0772	Belongs to the SEDS family
B34_00079	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B34_00080	COG0812	UDP-N-acetylmuramate dehydrogenase activity
B34_00081	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B34_00082	COG3879	Bacterial protein of unknown function (DUF881)
B34_00083	COG3879	Bacterial protein of unknown function (DUF881)
B34_00084	COG3856	small basic protein
B34_00085	COG0849	cell division
B34_00086	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B34_00087	COG4412	M6 family metalloprotease domain protein
B34_00087	COG1404	Belongs to the peptidase S8 family
B34_00088	COG4412	M6 family metalloprotease domain protein
B34_00088	COG1404	Belongs to the peptidase S8 family
B34_00089	COG4412	M6 family metalloprotease domain protein
B34_00089	COG1404	Belongs to the peptidase S8 family
B34_00091	COG1191	sigma factor activity
B34_00092	COG1191	sigma factor activity
B34_00093	COG1119	ATPase activity
B34_00094	COG0500	methyltransferase
B34_00095	COG1873	PFAM PRC-barrel domain
B34_00097	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B34_00098	COG1799	cell septum assembly
B34_00099	COG0762	integral membrane protein
B34_00100	COG2302	S4 RNA-binding domain
B34_00101	COG3599	regulation of cell shape
B34_00102	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B34_00103	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B34_00104	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
B34_00105	COG0564	pseudouridine synthase activity
B34_00106	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
B34_00107	COG2233	PERMEase
B34_00108	COG0540	Belongs to the ATCase OTCase family
B34_00109	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B34_00110	COG0505	Belongs to the CarA family
B34_00111	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B34_00112	COG0543	2 iron, 2 sulfur cluster binding
B34_00113	COG0167	dihydroorotate dehydrogenase activity
B34_00114	COG0284	orotidine-5'-phosphate decarboxylase activity
B34_00115	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
B34_00117	COG0175	sulfate reduction
B34_00118	COG0306	phosphate transporter
B34_00119	COG2046	Belongs to the sulfate adenylyltransferase family
B34_00120	COG0529	Catalyzes the synthesis of activated sulfate
B34_00121	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B34_00122	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
B34_00123	COG1648	precorrin-2 dehydrogenase activity
B34_00125	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B34_00126	COG1561	YicC-like family, N-terminal region
B34_00127	COG2052	Domain of unknown function (DUF370)
B34_00128	COG0194	GDP metabolic process
B34_00129	COG1758	RNA polymerase activity
B34_00130	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B34_00131	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B34_00132	COG0242	peptide deformylase activity
B34_00133	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B34_00134	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B34_00134	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B34_00135	COG0820	rRNA (adenine-C2-)-methyltransferase activity
B34_00136	COG0631	protein serine/threonine phosphatase activity
B34_00137	COG0515	serine threonine protein kinase
B34_00137	COG2815	serine threonine protein kinase
B34_00138	COG1162	GTPase activity
B34_00139	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B34_00140	COG1564	THIamine pyrophosphokinase
B34_00141	COG0227	Belongs to the bacterial ribosomal protein bL28 family
B34_00142	COG1302	Protein conserved in bacteria
B34_00143	COG1461	Dihydroxyacetone kinase
B34_00144	COG1760	l-serine dehydratase
B34_00145	COG1760	l-serine dehydratase
B34_00146	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B34_00147	COG1349	DNA-binding transcription factor activity
B34_00148	COG0416	fatty acid biosynthetic process
B34_00149	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B34_00150	COG1028	Short-chain dehydrogenase reductase Sdr
B34_00151	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B34_00152	COG0571	ribonuclease III activity
B34_00153	COG1196	nuclear chromosome segregation
B34_00154	COG0552	protein localization to endoplasmic reticulum
B34_00155	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
B34_00156	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B34_00157	COG0228	four-way junction DNA binding
B34_00158	COG1837	Belongs to the UPF0109 family
B34_00160	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B34_00161	COG0336	Belongs to the RNA methyltransferase TrmD family
B34_00162	COG0335	large ribosomal subunit rRNA binding
B34_00163	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
B34_00164	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B34_00166	COG2257	FlhB HrpN YscU SpaS Family
B34_00167	COG0045	succinate-CoA ligase (ADP-forming) activity
B34_00168	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B34_00169	COG0758	DNA mediated transformation
B34_00170	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B34_00171	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
B34_00172	COG4974	Belongs to the 'phage' integrase family
B34_00173	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
B34_00174	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
B34_00175	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
B34_00177	COG1815	bacterial-type flagellum-dependent cell motility
B34_00178	COG1558	bacterial-type flagellum-dependent cell motility
B34_00179	COG1677	Flagellar hook-basal body complex protein FliE
B34_00180	COG1766	The M ring may be actively involved in energy transduction
B34_00181	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B34_00182	COG1317	bacterial-type flagellum organization
B34_00183	COG1157	protein secretion by the type III secretion system
B34_00184	COG2882	bacterial-type flagellum organization
B34_00186	COG3144	bacterial-type flagellum assembly
B34_00187	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
B34_00188	COG4786	Flagellar basal body rod
B34_00189	COG1580	Controls the rotational direction of flagella during chemotaxis
B34_00190	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B34_00191	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B34_00191	COG1776	CheC inhibitor of MCP methylation
B34_00192	COG2201	protein-glutamate methylesterase activity
B34_00193	COG3190	flagellar
B34_00194	COG1338	Plays a role in the flagellum-specific transport system
B34_00195	COG1987	bacterial-type flagellum assembly
B34_00196	COG1684	flagellar biosynthetic protein fliR
B34_00197	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B34_00198	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B34_00199	COG1419	protein localization to endoplasmic reticulum
B34_00200	COG0455	bacterial-type flagellum organization
B34_00201	COG2201	protein-glutamate methylesterase activity
B34_00202	COG0643	Histidine kinase
B34_00202	COG2198	Histidine kinase
B34_00203	COG0835	chemotaxis
B34_00204	COG1776	CheC inhibitor of MCP methylation
B34_00205	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
B34_00206	COG1191	sigma factor activity
B34_00208	COG0052	Belongs to the universal ribosomal protein uS2 family
B34_00209	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
B34_00210	COG0528	UMP kinase activity
B34_00211	COG0233	cytoplasmic translational termination
B34_00212	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B34_00213	COG4589	Belongs to the CDS family
B34_00214	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
B34_00215	COG0750	zinc metalloprotease
B34_00216	COG0442	prolyl-tRNA aminoacylation
B34_00217	COG2176	DNA-directed DNA polymerase activity
B34_00223	COG0779	Required for maturation of 30S ribosomal subunits
B34_00224	COG0195	Participates in both transcription termination and antitermination
B34_00225	COG2740	Nucleic-acid-binding protein implicated in transcription termination
B34_00226	COG1358	cellular component organization or biogenesis
B34_00227	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
B34_00228	COG1550	Protein conserved in bacteria
B34_00229	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
B34_00230	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
B34_00231	COG0196	riboflavin kinase activity
B34_00232	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
B34_00233	COG1185	polyribonucleotide nucleotidyltransferase activity
B34_00234	COG0726	polysaccharide deacetylase
B34_00235	COG0612	Peptidase, M16
B34_00236	COG1873	PFAM PRC-barrel domain
B34_00237	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B34_00238	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B34_00239	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B34_00240	COG0527	aspartate kinase activity
B34_00242	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B34_00243	COG0740	serine-type endopeptidase activity
B34_00245	COG1674	ftsk spoiiie
B34_00245	COG4980	gas vesicle protein
B34_00246	COG2188	Transcriptional regulator
B34_00247	COG2814	Major facilitator Superfamily
B34_00248	COG0612	Peptidase, M16
B34_00249	COG0612	Peptidase, M16
B34_00250	COG0300	oxidoreductase activity
B34_00253	COG1426	Protein conserved in bacteria
B34_00254	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B34_00255	COG1058	Belongs to the CinA family
B34_00255	COG1546	Belongs to the CinA family
B34_00256	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
B34_00257	COG1418	mRNA catabolic process
B34_00258	COG1692	metallophosphoesterase
B34_00259	COG2359	stage V sporulation protein S
B34_00261	COG1063	alcohol dehydrogenase
B34_00262	COG0156	8-amino-7-oxononanoate synthase activity
B34_00263	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B34_00264	COG4550	Control of competence regulator ComK, YlbF/YmcA
B34_00266	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
B34_00267	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
B34_00268	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
B34_00269	COG5444	nuclease activity
B34_00272	COG0523	cobalamin synthesis protein
B34_00274	COG1247	-acetyltransferase
B34_00277	COG1231	oxidoreductase activity
B34_00278	COG3619	membrane
B34_00279	COG3263	regulation of cellular component size
B34_00280	COG2814	Major facilitator Superfamily
B34_00281	COG2814	Major facilitator Superfamily
B34_00282	COG2267	carboxylic ester hydrolase activity
B34_00283	COG0393	Putative heavy-metal-binding
B34_00284	COG0398	Pfam SNARE associated Golgi protein
B34_00285	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B34_00286	COG1819	glycosyl
B34_00287	COG0531	amino acid
B34_00288	COG5577	PFAM Coat F domain
B34_00290	COG1388	LysM domain
B34_00290	COG3858	chitin binding
B34_00291	COG3858	chitin binding
B34_00291	COG1388	LysM domain
B34_00292	COG1309	transcriptional regulator
B34_00293	COG3631	Ketosteroid isomerase-related protein
B34_00294	COG0702	epimerase
B34_00296	COG1764	response to oxidative stress
B34_00297	COG2076	Multidrug Resistance protein
B34_00298	COG2076	Multidrug Resistance protein
B34_00301	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
B34_00302	COG1923	regulation of RNA biosynthetic process
B34_00304	COG1780	Probably involved in ribonucleotide reductase function
B34_00305	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B34_00306	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B34_00307	COG4112	unkown
B34_00310	COG0822	iron-sulfur transferase activity
B34_00311	COG0735	belongs to the Fur family
B34_00312	COG1802	Transcriptional regulator
B34_00313	COG0697	spore germination
B34_00319	COG1309	transcriptional regulator
B34_00327	COG4282	regulation of fungal-type cell wall biogenesis
B34_00328	COG5444	nuclease activity
B34_00332	COG0464	growth
B34_00334	COG0840	transmembrane signaling receptor activity
B34_00335	COG2002	toxin-antitoxin pair type II binding
B34_00336	COG1028	Short-chain dehydrogenase reductase Sdr
B34_00337	COG5444	nuclease activity
B34_00344	COG2814	Major facilitator Superfamily
B34_00345	COG0457	Tetratricopeptide repeat
B34_00350	COG5632	N-Acetylmuramoyl-L-alanine amidase
B34_00352	COG5434	Belongs to the glycosyl hydrolase 28 family
B34_00354	COG2433	Pfam Transposase IS66
B34_00356	COG0741	lytic transglycosylase activity
B34_00356	COG1196	nuclear chromosome segregation
B34_00356	COG0739	heme binding
B34_00357	COG0739	heme binding
B34_00357	COG0741	lytic transglycosylase activity
B34_00357	COG1196	nuclear chromosome segregation
B34_00371	COG0582	viral genome integration into host DNA
B34_00390	COG4373	Mu-like prophage FluMu protein gp28
B34_00397	COG0776	regulation of translation
B34_00403	COG1404	Belongs to the peptidase S8 family
B34_00420	COG3655	Transcriptional regulator
B34_00444	COG0582	viral genome integration into host DNA
B34_00450	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B34_00461	COG1793	dna ligase
B34_00477	COG2887	Belongs to the helicase family. UvrD subfamily
B34_00479	COG0305	Participates in initiation and elongation during chromosome replication
B34_00480	COG0358	DNA primase activity
B34_00481	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B34_00482	COG0587	DNA-directed DNA polymerase activity
B34_00484	COG0587	DNA-directed DNA polymerase activity
B34_00486	COG0587	DNA-directed DNA polymerase activity
B34_00487	COG3584	3D domain protein
B34_00501	COG1780	Probably involved in ribonucleotide reductase function
B34_00502	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B34_00503	COG1372	Participates in initiation and elongation during chromosome replication
B34_00503	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B34_00506	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B34_00508	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B34_00512	COG0756	dUTP diphosphatase activity
B34_00520	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
B34_00524	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B34_00529	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
B34_00531	COG3331	DNA recombination
B34_00534	COG0464	growth
B34_00535	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B34_00536	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
B34_00537	COG0789	Transcriptional regulator
B34_00538	COG0174	glutamine synthetase
B34_00546	COG1073	alpha beta
B34_00555	COG1309	transcriptional regulator
B34_00556	COG2076	Multidrug Resistance protein
B34_00557	COG2076	Multidrug Resistance protein
B34_00559	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B34_00562	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B34_00563	COG3546	catalase activity
B34_00568	COG1846	Transcriptional regulator
B34_00569	COG0778	Nitroreductase
B34_00570	COG0346	lactoylglutathione lyase activity
B34_00571	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B34_00572	COG0655	NAD(P)H dehydrogenase (quinone) activity
B34_00575	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
B34_00576	COG3209	COG3209 Rhs family protein
B34_00577	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B34_00578	COG1388	LysM domain
B34_00579	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
B34_00580	COG4224	UPF0291 protein
B34_00581	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B34_00583	COG3763	UPF0154 protein
B34_00585	COG0785	Cytochrome C biogenesis protein
B34_00586	COG2201	protein-glutamate methylesterase activity
B34_00587	COG4846	Membrane protein involved in cytochrome C biogenesis
B34_00589	COG0071	Belongs to the small heat shock protein (HSP20) family
B34_00590	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B34_00591	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B34_00595	COG0824	Thioesterase
B34_00599	COG4841	protein insertion into membrane
B34_00600	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
B34_00601	COG1832	CoA-binding protein
B34_00602	COG0187	DNA topoisomerase II activity
B34_00603	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B34_00604	COG1609	Transcriptional regulator
B34_00607	COG2160	L-arabinose isomerase activity
B34_00612	COG1115	amino acid carrier protein
B34_00614	COG2181	nitrate reductase activity
B34_00615	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
B34_00616	COG1140	nitrate reductase beta subunit
B34_00617	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
B34_00621	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B34_00623	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B34_00624	COG2223	nitrite transmembrane transporter activity
B34_00626	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B34_00628	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
B34_00630	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
B34_00632	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B34_00634	COG0477	Major facilitator Superfamily
B34_00635	COG3420	alginic acid biosynthetic process
B34_00636	COG1114	Component of the transport system for branched-chain amino acids
B34_00637	COG1064	alcohol dehydrogenase
B34_00638	COG0789	Transcriptional regulator
B34_00643	COG1024	Enoyl-CoA hydratase
B34_00644	COG1012	belongs to the aldehyde dehydrogenase family
B34_00645	COG2084	Dehydrogenase
B34_00646	COG1960	acyl-CoA dehydrogenase activity
B34_00647	COG1482	cell wall glycoprotein biosynthetic process
B34_00648	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B34_00648	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B34_00648	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B34_00652	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B34_00652	COG3711	transcriptional antiterminator
B34_00655	COG1725	Transcriptional regulator
B34_00656	COG1028	Short-chain dehydrogenase reductase Sdr
B34_00657	COG1312	Catalyzes the dehydration of D-mannonate
B34_00660	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B34_00662	COG1609	Transcriptional regulator
B34_00663	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B34_00664	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B34_00665	COG0640	Transcriptional regulator
B34_00666	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
B34_00669	COG1649	PFAM Uncharacterised BCR, COG1649
B34_00670	COG2404	hydrolase activity, acting on ester bonds
B34_00671	COG2404	hydrolase activity, acting on ester bonds
B34_00672	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B34_00674	COG2027	D-alanyl-D-alanine carboxypeptidase
B34_00675	COG2323	membrane
B34_00676	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B34_00678	COG2323	membrane
B34_00681	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B34_00685	COG3546	catalase activity
B34_00689	COG0860	N-Acetylmuramoyl-L-alanine amidase
B34_00693	COG1252	NADH dehydrogenase
B34_00696	COG0166	Belongs to the GPI family
B34_00698	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B34_00699	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B34_00700	COG1024	Enoyl-CoA hydratase
B34_00701	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B34_00702	COG0511	ligase activity, forming carbon-carbon bonds
B34_00703	COG0439	Biotin carboxylase
B34_00704	COG0318	PFAM AMP-dependent synthetase and ligase
B34_00705	COG1960	acyl-CoA dehydrogenase activity
B34_00706	COG2249	NAD(P)H dehydrogenase (quinone) activity
B34_00707	COG1733	regulation of RNA biosynthetic process
B34_00708	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
B34_00709	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
B34_00712	COG2323	membrane
B34_00713	COG0306	phosphate transporter
B34_00714	COG0175	sulfate reduction
B34_00715	COG1809	phosphosulfolactate synthase activity
B34_00716	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B34_00717	COG4948	Mandelate Racemase Muconate Lactonizing
B34_00718	COG4948	Mandelate Racemase Muconate Lactonizing
B34_00719	COG2814	Major facilitator Superfamily
B34_00720	COG0463	Glycosyl transferase, family 2
B34_00723	COG0493	'glutamate synthase
B34_00724	COG0070	glutamate synthase
B34_00724	COG0069	glutamate synthase activity
B34_00724	COG0067	glutamate synthase
B34_00725	COG0583	DNA-binding transcription factor activity
B34_00729	COG1846	Transcriptional regulator
B34_00731	COG1132	(ABC) transporter
B34_00733	COG0300	oxidoreductase activity
B34_00734	COG3848	Pyruvate phosphate dikinase
B34_00734	COG0574	Belongs to the PEP-utilizing enzyme family
B34_00735	COG0477	Major facilitator Superfamily
B34_00736	COG0243	molybdopterin cofactor binding
B34_00737	COG1846	Transcriptional regulator
B34_00738	COG2814	Major facilitator Superfamily
B34_00739	COG0531	amino acid
B34_00741	COG0531	amino acid
B34_00742	COG0531	amino acid
B34_00743	COG0697	spore germination
B34_00745	COG0840	transmembrane signaling receptor activity
B34_00746	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B34_00747	COG1404	Belongs to the peptidase S8 family
B34_00749	COG1309	transcriptional regulator
B34_00750	COG1846	Transcriptional regulator
B34_00756	COG1309	transcriptional regulator
B34_00757	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B34_00758	COG3708	Transcriptional regulator
B34_00760	COG2378	regulation of single-species biofilm formation
B34_00762	COG0640	Transcriptional regulator
B34_00763	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B34_00765	COG0531	amino acid
B34_00766	COG0741	lytic transglycosylase activity
B34_00767	COG1086	Polysaccharide biosynthesis protein
B34_00771	COG2801	Transposase and inactivated derivatives
B34_00773	COG2322	membrane
B34_00776	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B34_00777	COG3584	3D domain protein
B34_00777	COG1388	LysM domain
B34_00778	COG0514	ATP-dependent DNA helicase (RecQ)
B34_00783	COG2315	Protein conserved in bacteria
B34_00786	COG2427	Protein of unknown function (DUF1641)
B34_00787	COG3383	formate dehydrogenase (NAD+) activity
B34_00790	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
B34_00800	COG0402	S-adenosylhomocysteine deaminase activity
B34_00803	COG2267	carboxylic ester hydrolase activity
B34_00806	COG1280	lysine exporter protein (LysE YggA)
B34_00807	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B34_00809	COG3848	Pyruvate phosphate dikinase
B34_00809	COG0574	Belongs to the PEP-utilizing enzyme family
B34_00810	COG1309	transcriptional regulator
B34_00813	COG2318	DinB family
B34_00814	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B34_00815	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B34_00818	COG1012	belongs to the aldehyde dehydrogenase family
B34_00819	COG2814	Major facilitator Superfamily
B34_00822	COG1657	PFAM Prenyltransferase squalene oxidase
B34_00823	COG1657	PFAM Prenyltransferase squalene oxidase
B34_00824	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B34_00826	COG0733	neurotransmitter:sodium symporter activity
B34_00827	COG0385	Bile acid
B34_00828	COG0508	dehydrogenase complex catalyzes the overall conversion of
B34_00829	COG0567	Dehydrogenase, E1 component
B34_00830	COG4548	von Willebrand factor, type A
B34_00831	COG0714	Associated with various cellular activities
B34_00832	COG2032	superoxide dismutase activity
B34_00833	COG1388	LysM domain
B34_00833	COG0791	NLP P60 protein
B34_00834	COG0534	Mate efflux family protein
B34_00835	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B34_00836	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B34_00838	COG2962	Rard protein
B34_00841	COG4305	rare lipoprotein A
B34_00843	COG1028	Short-chain dehydrogenase reductase Sdr
B34_00844	COG1733	regulation of RNA biosynthetic process
B34_00845	COG0778	Nitroreductase
B34_00846	COG0400	carboxylic ester hydrolase activity
B34_00848	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B34_00849	COG3409	Peptidoglycan-binding domain 1 protein
B34_00849	COG0793	Belongs to the peptidase S41A family
B34_00850	COG2226	methyltransferase
B34_00852	COG1876	peptidase activity
B34_00853	COG0813	purine-nucleoside phosphorylase activity
B34_00854	COG0701	Predicted permease
B34_00858	COG0671	phosphoesterase, PA-phosphatase related
B34_00862	COG4479	Belongs to the UPF0346 family
B34_00864	COG1509	lysine 2,3-aminomutase activity
B34_00865	COG0456	acetyltransferase
B34_00866	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B34_00867	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B34_00868	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B34_00869	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B34_00871	COG0456	acetyltransferase
B34_00872	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B34_00873	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B34_00874	COG1846	Transcriptional regulator
B34_00876	COG3706	GGDEF domain
B34_00877	COG0534	Mate efflux family protein
B34_00880	COG4698	Protein conserved in bacteria
B34_00881	COG2755	lipolytic protein G-D-S-L family
B34_00882	COG1999	signal sequence binding
B34_00885	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B34_00886	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
B34_00887	COG1272	protein, Hemolysin III
B34_00888	COG0204	Acyl-transferase
B34_00889	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B34_00890	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B34_00893	COG2136	Putative SAM-dependent methyltransferase
B34_00893	COG2521	methyltransferase
B34_00895	COG0129	dihydroxy-acid dehydratase activity
B34_00896	COG1413	lyase activity
B34_00897	COG1418	mRNA catabolic process
B34_00898	COG0386	Belongs to the glutathione peroxidase family
B34_00899	COG2759	Belongs to the formate--tetrahydrofolate ligase family
B34_00900	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
B34_00901	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B34_00903	COG1278	Cold shock
B34_00907	COG0328	RNA-DNA hybrid ribonuclease activity
B34_00908	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
B34_00909	COG0328	RNA-DNA hybrid ribonuclease activity
B34_00910	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B34_00913	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
B34_00914	COG1755	Isoprenylcysteine carboxyl methyltransferase
B34_00915	COG3424	synthase
B34_00916	COG0456	acetyltransferase
B34_00917	COG2233	PERMEase
B34_00918	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B34_00919	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
B34_00920	COG1199	ATP-dependent helicase activity
B34_00923	COG0116	Belongs to the methyltransferase superfamily
B34_00924	COG3599	regulation of cell shape
B34_00925	COG4474	Belongs to the UPF0398 family
B34_00928	COG3359	exonuclease
B34_00929	COG1111	helicase
B34_00929	COG1205	dead DEAH box helicase
B34_00930	COG2190	(PTS) system
B34_00931	COG0071	Belongs to the small heat shock protein (HSP20) family
B34_00937	COG3331	DNA recombination
B34_00938	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B34_00938	COG4499	WXG100 protein secretion system (Wss), protein YukC
B34_00940	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B34_00941	COG3935	DnaD domain protein
B34_00942	COG0017	Asparaginyl-tRNA synthetase
B34_00943	COG0436	Aminotransferase
B34_00944	COG5353	protein conserved in bacteria
B34_00946	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B34_00946	COG1199	ATP-dependent helicase activity
B34_00947	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
B34_00948	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
B34_00949	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
B34_00951	COG0617	tRNA 3'-terminal CCA addition
B34_00952	COG0438	transferase activity, transferring glycosyl groups
B34_00953	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B34_00954	COG1803	Methylglyoxal synthase
B34_00955	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
B34_00956	COG1694	Mazg nucleotide pyrophosphohydrolase
B34_00957	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B34_00959	COG4347	Protein of unknown function (DUF1405)
B34_00960	COG2010	Cytochrome c
B34_00960	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B34_00961	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B34_00962	COG0723	plastoquinol--plastocyanin reductase activity
B34_00964	COG5582	Belongs to the UPF0302 family
B34_00965	COG0457	Tetratricopeptide repeat
B34_00966	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B34_00967	COG0287	Prephenate dehydrogenase
B34_00968	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B34_00969	COG0159	tryptophan synthase activity
B34_00970	COG0133	tryptophan synthase activity
B34_00971	COG0135	phosphoribosylanthranilate isomerase activity
B34_00972	COG0134	indole-3-glycerol-phosphate synthase activity
B34_00973	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B34_00974	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B34_00975	COG4401	Chorismate mutase type I
B34_00976	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B34_00977	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
B34_00978	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B34_00979	COG0105	UTP biosynthetic process
B34_00980	COG0142	geranyltranstransferase activity
B34_00981	COG2226	methyltransferase
B34_00982	COG0142	geranyltranstransferase activity
B34_00985	COG0776	regulation of translation
B34_00986	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
B34_00990	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
B34_00991	COG1160	GTP binding
B34_00996	COG1304	FMN binding
B34_00997	COG0539	negative regulation of cytoplasmic translation
B34_00998	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
B34_01000	COG2959	enzyme of heme biosynthesis
B34_01001	COG3409	Peptidoglycan-binding domain 1 protein
B34_01001	COG3773	Cell wall hydrolase
B34_01002	COG2339	peptidase activity
B34_01004	COG0492	ferredoxin-NADP+ reductase activity
B34_01005	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B34_01006	COG4862	establishment of competence for transformation
B34_01007	COG1408	metallophosphoesterase
B34_01009	COG1388	LysM domain
B34_01010	COG1266	CAAX protease self-immunity
B34_01011	COG0514	ATP-dependent DNA helicase (RecQ)
B34_01012	COG4955	Helix-turn-helix domain
B34_01013	COG1141	Ferredoxin
B34_01014	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
B34_01015	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B34_01016	COG0739	heme binding
B34_01018	COG1595	DNA-templated transcription, initiation
B34_01022	COG5002	protein histidine kinase activity
B34_01023	COG0745	RESPONSE REGULATOR receiver
B34_01024	COG5002	protein histidine kinase activity
B34_01025	COG0745	RESPONSE REGULATOR receiver
B34_01026	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B34_01027	COG1333	cytochrome c biogenesis protein
B34_01028	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B34_01029	COG1187	pseudouridine synthase activity
B34_01030	COG0700	Nucleoside recognition
B34_01031	COG2715	membrane protein required for spore maturation
B34_01032	COG1686	Belongs to the peptidase S11 family
B34_01034	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B34_01035	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
B34_01037	COG1547	Domain of unknown function (DUF309)
B34_01038	COG0456	acetyltransferase
B34_01039	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
B34_01040	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B34_01040	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B34_01041	COG0307	riboflavin synthase, alpha
B34_01042	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B34_01042	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B34_01047	COG0457	Tetratricopeptide repeat
B34_01048	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B34_01049	COG4086	secreted protein
B34_01050	COG4195	phage-related replication protein
B34_01051	COG0019	diaminopimelate decarboxylase activity
B34_01053	COG0697	spore germination
B34_01056	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B34_01061	COG2172	sigma factor antagonist activity
B34_01063	COG1686	Belongs to the peptidase S11 family
B34_01064	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
B34_01065	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
B34_01066	COG4974	Belongs to the 'phage' integrase family
B34_01068	COG0735	belongs to the Fur family
B34_01069	COG1300	Membrane
B34_01070	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B34_01072	COG1953	Uracil, thiamine, allantoin
B34_01073	COG1953	Uracil, thiamine, allantoin
B34_01076	COG2153	protein acetylation
B34_01077	COG1379	DNA repair
B34_01078	COG0494	nUDIX hydrolase
B34_01080	COG1309	transcriptional regulator
B34_01082	COG0667	Aldo Keto reductase
B34_01084	COG1073	alpha beta
B34_01086	COG4918	Iron-sulphur cluster biosynthesis
B34_01088	COG0456	acetyltransferase
B34_01088	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
B34_01089	COG2329	Antibiotic biosynthesis monooxygenase
B34_01090	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
B34_01092	COG0747	negative chemotaxis
B34_01093	COG0601	transmembrane transport
B34_01094	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B34_01095	COG0444	Belongs to the ABC transporter superfamily
B34_01096	COG0534	Mate efflux family protein
B34_01100	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B34_01102	COG2211	Major facilitator Superfamily
B34_01103	COG0346	lactoylglutathione lyase activity
B34_01104	COG1072	(Pantothenic acid kinase))
B34_01110	COG4195	phage-related replication protein
B34_01111	COG0300	oxidoreductase activity
B34_01112	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B34_01113	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B34_01114	COG4187	Peptidase family M20/M25/M40
B34_01115	COG1902	pentaerythritol trinitrate reductase activity
B34_01116	COG0596	Alpha beta hydrolase
B34_01117	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B34_01118	COG1234	tRNA 3'-trailer cleavage
B34_01119	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
B34_01123	COG2188	Transcriptional regulator
B34_01124	COG2723	6-phospho-beta-galactosidase activity
B34_01125	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B34_01126	COG1447	Phosphotransferase system cellobiose-specific component IIA
B34_01127	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B34_01129	COG1785	Belongs to the alkaline phosphatase family
B34_01130	COG1028	Short-chain dehydrogenase reductase Sdr
B34_01131	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
B34_01132	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B34_01134	COG0706	membrane insertase activity
B34_01135	COG2195	Cleaves the N-terminal amino acid of tripeptides
B34_01136	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B34_01137	COG4129	membrane
B34_01138	COG1126	abc transporter atp-binding protein
B34_01139	COG0765	amino acid transport
B34_01140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B34_01143	COG1597	lipid kinase activity
B34_01144	COG0508	dehydrogenase complex catalyzes the overall conversion of
B34_01145	COG0022	dehydrogenase e1 component
B34_01146	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B34_01147	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B34_01148	COG3426	butyrate kinase activity
B34_01150	COG0280	phosphate acetyltransferase
B34_01151	COG3829	transcription factor binding
B34_01151	COG3290	protein histidine kinase activity
B34_01153	COG0584	glycerophosphoryl diester phosphodiesterase
B34_01154	COG0860	N-Acetylmuramoyl-L-alanine amidase
B34_01156	COG1045	serine acetyltransferase
B34_01158	COG0745	RESPONSE REGULATOR receiver
B34_01159	COG0750	zinc metalloprotease
B34_01160	COG0497	DNA recombination
B34_01161	COG1438	arginine binding
B34_01162	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
B34_01163	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B34_01164	COG0142	geranyltranstransferase activity
B34_01165	COG1722	exodeoxyribonuclease VII activity
B34_01166	COG1570	exodeoxyribonuclease VII activity
B34_01167	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B34_01168	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B34_01169	COG1302	Protein conserved in bacteria
B34_01170	COG0439	Biotin carboxylase
B34_01171	COG0511	ligase activity, forming carbon-carbon bonds
B34_01179	COG3854	ATPases associated with a variety of cellular activities
B34_01181	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B34_01182	COG0006	proline dipeptidase activity
B34_01183	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
B34_01185	COG3872	metal-dependent enzyme
B34_01187	COG1752	Esterase of the alpha-beta hydrolase superfamily
B34_01188	COG1321	iron dependent repressor
B34_01189	COG0095	Lipoate-protein ligase
B34_01190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B34_01191	COG2113	Glycine betaine
B34_01192	COG4176	ABC-type proline glycine betaine transport system permease component
B34_01193	COG4175	Glycine betaine
B34_01193	COG0517	IMP dehydrogenase activity
B34_01194	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B34_01195	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B34_01196	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B34_01197	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B34_01202	COG0681	Belongs to the peptidase S26 family
B34_01207	COG4940	Competence protein ComGF
B34_01208	COG4970	Tfp pilus assembly protein FimT
B34_01209	COG4537	Required for transformation and DNA binding
B34_01224	COG3778	Protein conserved in bacteria
B34_01225	COG3299	homolog of phage Mu protein gp47
B34_01226	COG3628	GPW Gp25 family protein
B34_01228	COG4193	domain, Protein
B34_01229	COG1652	LysM domain
B34_01230	COG5280	Phage tail tape measure protein TP901
B34_01230	COG3953	SLT domain
B34_01230	COG5280	Phage tail tape measure protein TP901
B34_01230	COG3953	SLT domain
B34_01241	COG4653	Phage capsid family
B34_01242	COG0338	D12 class N6 adenine-specific DNA methyltransferase
B34_01244	COG2369	cell adhesion
B34_01245	COG5518	Phage portal protein
B34_01246	COG1783	phage Terminase large subunit
B34_01252	COG5444	nuclease activity
B34_01253	COG0457	Tetratricopeptide repeat
B34_01260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B34_01265	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
B34_01269	COG0305	Participates in initiation and elongation during chromosome replication
B34_01273	COG3723	Recombinational DNA repair protein, rece pathway
B34_01274	COG5377	YqaJ viral recombinase family
B34_01283	COG1396	sequence-specific DNA binding
B34_01284	COG2856	Zn peptidase
B34_01287	COG1459	type II secretion system
B34_01288	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B34_01289	COG1366	Belongs to the anti-sigma-factor antagonist family
B34_01291	COG1393	Belongs to the ArsC family
B34_01293	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B34_01295	COG0011	TIGRFAM Protein of
B34_01297	COG2866	Carboxypeptidase
B34_01298	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B34_01300	COG1368	sulfuric ester hydrolase activity
B34_01301	COG1940	carbohydrate kinase activity
B34_01302	COG0697	spore germination
B34_01303	COG0457	Tetratricopeptide repeat
B34_01303	COG0705	Rhomboid family
B34_01305	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B34_01306	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B34_01307	COG0438	transferase activity, transferring glycosyl groups
B34_01310	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B34_01311	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B34_01312	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B34_01313	COG0581	inorganic phosphate transmembrane transporter activity
B34_01314	COG0573	inorganic phosphate transmembrane transporter activity
B34_01315	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B34_01317	COG0477	Major facilitator Superfamily
B34_01318	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B34_01319	COG2839	Protein conserved in bacteria
B34_01320	COG5521	maltodextrose utilization protein MalA
B34_01321	COG1388	LysM domain
B34_01322	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
B34_01323	COG4709	membrane
B34_01324	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
B34_01325	COG0735	belongs to the Fur family
B34_01326	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B34_01327	COG1121	(ABC) transporter
B34_01328	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B34_01330	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
B34_01331	COG0513	Belongs to the DEAD box helicase family
B34_01333	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
B34_01334	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B34_01335	COG2384	SAM-dependent methyltransferase
B34_01346	COG5444	nuclease activity
B34_01349	COG2010	Cytochrome c
B34_01350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B34_01351	COG0358	DNA primase activity
B34_01352	COG1671	Belongs to the UPF0178 family
B34_01353	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
B34_01354	COG0517	IMP dehydrogenase activity
B34_01355	COG0751	glycine-tRNA ligase activity
B34_01356	COG0752	glycyl-tRNA synthetase alpha subunit
B34_01357	COG1381	Involved in DNA repair and RecF pathway recombination
B34_01359	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
B34_01360	COG0295	cytidine deaminase activity
B34_01361	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
B34_01362	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
B34_01363	COG1480	7TM receptor with intracellular HD hydrolase
B34_01364	COG1702	phosphate starvation-inducible protein PhoH
B34_01365	COG0561	phosphatase activity
B34_01368	COG4864	UPF0365 protein
B34_01369	COG1030	water channel activity
B34_01370	COG1610	YqeY-like protein
B34_01371	COG0828	Belongs to the bacterial ribosomal protein bS21 family
B34_01372	COG1283	sodium-dependent phosphate transmembrane transporter activity
B34_01373	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
B34_01374	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B34_01375	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B34_01376	COG2264	protein methyltransferase activity
B34_01377	COG0484	heat shock protein binding
B34_01378	COG0443	Heat shock 70 kDa protein
B34_01379	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B34_01380	COG1420	regulation of RNA biosynthetic process
B34_01381	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B34_01382	COG0481	GTPase activity
B34_01384	COG0860	N-Acetylmuramoyl-L-alanine amidase
B34_01385	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
B34_01386	COG0268	Binds directly to 16S ribosomal RNA
B34_01387	COG1466	dna polymerase III delta subunit
B34_01389	COG0658	competence protein
B34_01389	COG2333	competence protein COMEC
B34_01390	COG2131	deaminase
B34_01391	COG1596	polysaccharide export
B34_01391	COG1555	photosystem II stabilization
B34_01392	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B34_01393	COG2226	methyltransferase
B34_01394	COG0799	negative regulation of ribosome biogenesis
B34_01395	COG1713	HD superfamily hydrolase involved in NAD metabolism
B34_01396	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
B34_01397	COG1534	Rna-binding protein
B34_01398	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B34_01399	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
B34_01400	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
B34_01402	COG2755	lipolytic protein G-D-S-L family
B34_01403	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B34_01404	COG5609	conserved protein (DUF2294)
B34_01405	COG3383	formate dehydrogenase (NAD+) activity
B34_01406	COG2427	Protein of unknown function (DUF1641)
B34_01413	COG0860	N-Acetylmuramoyl-L-alanine amidase
B34_01424	COG2197	response regulator
B34_01425	COG4585	Histidine kinase
B34_01426	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B34_01427	COG0730	response to heat
B34_01428	COG0425	Belongs to the sulfur carrier protein TusA family
B34_01429	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B34_01429	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B34_01430	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B34_01430	COG0425	Belongs to the sulfur carrier protein TusA family
B34_01431	COG2210	Belongs to the sulfur carrier protein TusA family
B34_01432	COG1937	Protein conserved in bacteria
B34_01436	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
B34_01438	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
B34_01439	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
B34_01440	COG1733	regulation of RNA biosynthetic process
B34_01441	COG3239	Fatty acid desaturase
B34_01442	COG4585	Histidine kinase
B34_01443	COG2197	response regulator
B34_01444	COG0492	ferredoxin-NADP+ reductase activity
B34_01445	COG0747	negative chemotaxis
B34_01446	COG0747	negative chemotaxis
B34_01447	COG0601	transmembrane transport
B34_01449	COG0444	Belongs to the ABC transporter superfamily
B34_01450	COG4608	Belongs to the ABC transporter superfamily
B34_01455	COG1028	Short-chain dehydrogenase reductase Sdr
B34_01458	COG2124	cytochrome p450
B34_01459	COG0730	response to heat
B34_01461	COG1028	Short-chain dehydrogenase reductase Sdr
B34_01462	COG1621	beta-fructofuranosidase activity
B34_01463	COG3716	PTS system mannose fructose sorbose family IID component
B34_01464	COG3715	PTS system
B34_01465	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B34_01466	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
B34_01467	COG3933	PFAM sigma-54 factor interaction domain-containing protein
B34_01467	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
B34_01470	COG2169	Transcriptional regulator
B34_01471	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B34_01472	COG0656	L-ascorbic acid biosynthetic process
B34_01473	COG2814	Major facilitator Superfamily
B34_01474	COG1733	regulation of RNA biosynthetic process
B34_01475	COG3340	Belongs to the peptidase S51 family
B34_01476	COG1587	Uroporphyrinogen-III synthase
B34_01478	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B34_01479	COG0583	DNA-binding transcription factor activity
B34_01480	COG2814	Major facilitator Superfamily
B34_01482	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B34_01482	COG2124	cytochrome p450
B34_01483	COG1309	transcriptional regulator
B34_01484	COG1404	Belongs to the peptidase S8 family
B34_01485	COG2226	methyltransferase
B34_01489	COG0626	cystathionine gamma-synthase activity
B34_01490	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B34_01491	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B34_01492	COG2226	methyltransferase
B34_01495	COG0768	penicillin binding
B34_01496	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B34_01497	COG0572	uridine kinase
B34_01501	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B34_01502	COG3906	Belongs to the UPF0473 family
B34_01503	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
B34_01504	COG4472	Bacterial protein of unknown function (DUF965)
B34_01505	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B34_01506	COG0628	permease
B34_01508	COG3881	PFAM PRC-barrel domain
B34_01509	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B34_01510	COG0457	Tetratricopeptide repeat
B34_01511	COG0482	sulfurtransferase activity
B34_01512	COG1104	cysteine desulfurase activity
B34_01513	COG1959	2 iron, 2 sulfur cluster binding
B34_01514	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B34_01515	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
B34_01516	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
B34_01517	COG0124	histidyl-tRNA synthetase
B34_01519	COG0860	N-Acetylmuramoyl-L-alanine amidase
B34_01519	COG3103	Sh3 type 3 domain protein
B34_01519	COG4991	sh3 domain protein
B34_01520	COG1490	D-aminoacyl-tRNA deacylase activity
B34_01521	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B34_01522	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B34_01523	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
B34_01523	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B34_01524	COG5416	Lipopolysaccharide assembly protein A domain
B34_01525	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B34_01525	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B34_01527	COG2244	polysaccharide biosynthetic process
B34_01528	COG2323	membrane
B34_01530	COG1862	Preprotein translocase
B34_01531	COG0343	queuine tRNA-ribosyltransferase activity
B34_01532	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
B34_01534	COG2255	four-way junction helicase activity
B34_01535	COG0632	four-way junction helicase activity
B34_01537	COG2112	serine threonine protein kinase
B34_01540	COG2318	DinB family
B34_01541	COG4195	phage-related replication protein
B34_01544	COG0217	transcriptional regulatory protein
B34_01546	COG1388	LysM domain
B34_01547	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
B34_01548	COG0157	Belongs to the NadC ModD family
B34_01549	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
B34_01550	COG1104	cysteine desulfurase activity
B34_01551	COG1827	regulation of RNA biosynthetic process
B34_01552	COG0077	Prephenate dehydratase
B34_01553	COG4492	Belongs to the UPF0735 family
B34_01554	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B34_01555	COG3290	protein histidine kinase activity
B34_01556	COG0211	Belongs to the bacterial ribosomal protein bL27 family
B34_01557	COG2868	ribosomal protein
B34_01558	COG0261	This protein binds to 23S rRNA in the presence of protein L20
B34_01559	COG1994	Peptidase M50
B34_01560	COG0739	heme binding
B34_01561	COG3832	glyoxalase III activity
B34_01562	COG0640	Transcriptional regulator
B34_01563	COG2894	cell division
B34_01564	COG0850	regulation of cytokinetic process
B34_01565	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
B34_01566	COG1792	Involved in formation and maintenance of cell shape
B34_01567	COG1077	Cell shape determining protein MreB Mrl
B34_01568	COG2003	Belongs to the UPF0758 family
B34_01569	COG0424	maF-like protein
B34_01571	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
B34_01572	COG0285	dihydrofolate synthase activity
B34_01573	COG0525	valine-tRNA ligase activity
B34_01575	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B34_01576	COG1388	LysM domain
B34_01577	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B34_01578	COG0113	porphobilinogen synthase activity
B34_01579	COG1587	Uroporphyrinogen-III synthase
B34_01580	COG0181	hydroxymethylbilane synthase activity
B34_01581	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B34_01582	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
B34_01584	COG0218	Necessary for normal cell division and for the maintenance of normal septation
B34_01585	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B34_01586	COG0470	DNA polymerase III
B34_01586	COG1067	ATP-dependent peptidase activity
B34_01587	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
B34_01588	COG0544	peptidyl-prolyl cis-trans isomerase activity
B34_01589	COG1477	protein flavinylation
B34_01589	COG0457	Tetratricopeptide repeat
B34_01590	COG0066	3-isopropylmalate dehydratase activity
B34_01591	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
B34_01592	COG0473	3-isopropylmalate dehydrogenase activity
B34_01593	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B34_01594	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
B34_01595	COG0440	acetolactate synthase activity
B34_01596	COG0028	Belongs to the TPP enzyme family
B34_01597	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B34_01602	COG5518	Phage portal protein
B34_01603	COG1783	phage Terminase large subunit
B34_01610	COG5444	nuclease activity
B34_01611	COG0457	Tetratricopeptide repeat
B34_01616	COG0622	Phosphoesterase
B34_01617	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
B34_01618	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
B34_01619	COG5401	PFAM Sporulation and spore germination
B34_01620	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B34_01621	COG1846	Transcriptional regulator
B34_01622	COG2197	response regulator
B34_01623	COG4221	oxidoreductase activity
B34_01624	COG0824	Thioesterase
B34_01625	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B34_01626	COG1053	succinate dehydrogenase
B34_01627	COG2009	succinate dehydrogenase
B34_01628	COG1719	4-vinyl reductase, 4VR
B34_01629	COG0527	aspartate kinase activity
B34_01630	COG0322	excinuclease ABC activity
B34_01631	COG3118	belongs to the thioredoxin family
B34_01632	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B34_01633	COG2086	electron transfer activity
B34_01634	COG1024	Enoyl-CoA hydratase
B34_01635	COG1309	transcriptional regulator
B34_01636	COG0318	PFAM AMP-dependent synthetase and ligase
B34_01637	COG3766	membrane
B34_01638	COG1193	negative regulation of DNA recombination
B34_01639	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
B34_01639	COG1796	DNA polymerase
B34_01640	COG1286	toxin biosynthetic process
B34_01641	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
B34_01642	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B34_01646	COG1137	ATPase activity
B34_01649	COG0072	phenylalanine-tRNA ligase activity
B34_01649	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B34_01650	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
B34_01651	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B34_01653	COG1966	Carbon starvation protein
B34_01656	COG0395	ABC-type sugar transport system, permease component
B34_01657	COG1175	transmembrane transport
B34_01658	COG1653	transport
B34_01659	COG0371	Dehydrogenase
B34_01660	COG0235	Class ii aldolase
B34_01661	COG1069	ribulokinase activity
B34_01662	COG2160	L-arabinose isomerase activity
B34_01663	COG2160	L-arabinose isomerase activity
B34_01664	COG3507	Belongs to the glycosyl hydrolase 43 family
B34_01665	COG1363	Peptidase, m42
B34_01667	COG3326	Membrane
B34_01668	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
B34_01669	COG0291	Belongs to the bacterial ribosomal protein bL35 family
B34_01670	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
B34_01671	COG1346	cytolysis
B34_01673	COG3540	Alkaline phosphatase
B34_01674	COG3279	Response regulator of the LytR AlgR family
B34_01675	COG3275	phosphorelay sensor kinase activity
B34_01678	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B34_01680	COG0398	Pfam SNARE associated Golgi protein
B34_01681	COG1484	DNA-dependent DNA replication
B34_01682	COG3611	Membrane attachment protein
B34_01683	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B34_01685	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
B34_01686	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B34_01687	COG3866	Pectate lyase
B34_01688	COG0237	dephospho-CoA kinase activity
B34_01689	COG1971	Probably functions as a manganese efflux pump
B34_01690	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B34_01691	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B34_01691	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B34_01692	COG5002	protein histidine kinase activity
B34_01693	COG0745	RESPONSE REGULATOR receiver
B34_01694	COG0039	L-malate dehydrogenase activity
B34_01695	COG0538	isocitrate dehydrogenase activity
B34_01696	COG0372	Belongs to the citrate synthase family
B34_01697	COG2707	UPF0756 membrane protein
B34_01698	COG0628	permease
B34_01699	COG3030	protein affecting phage T7 exclusion by the F plasmid
B34_01701	COG0205	6-phosphofructokinase activity
B34_01702	COG0825	malonyl-CoA metabolic process
B34_01703	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
B34_01704	COG0281	malic enzyme
B34_01705	COG0587	DNA-directed DNA polymerase activity
B34_01709	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
B34_01711	COG4109	DRTGG domain
B34_01712	COG1695	Transcriptional regulator
B34_01713	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B34_01714	COG1028	Short-chain dehydrogenase reductase Sdr
B34_01716	COG0165	Argininosuccinate lyase
B34_01717	COG0137	argininosuccinate synthase activity
B34_01718	COG0521	Mo-molybdopterin cofactor biosynthetic process
B34_01719	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B34_01720	COG0827	DNA restriction-modification system
B34_01721	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
B34_01722	COG3874	Sporulation protein YtfJ
B34_01724	COG1714	RDD family
B34_01725	COG0616	signal peptide processing
B34_01726	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B34_01727	COG1566	PFAM secretion protein HlyD family protein
B34_01729	COG0477	Major facilitator Superfamily
B34_01731	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B34_01733	COG0301	tRNA thio-modification
B34_01734	COG1104	cysteine desulfurase activity
B34_01735	COG1114	Component of the transport system for branched-chain amino acids
B34_01737	COG2801	Transposase and inactivated derivatives
B34_01738	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
B34_01739	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
B34_01740	COG1309	transcriptional regulator
B34_01741	COG1956	GAF domain-containing protein
B34_01742	COG2199	diguanylate cyclase activity
B34_01742	COG2203	Gaf domain
B34_01743	COG2199	diguanylate cyclase activity
B34_01743	COG2203	Gaf domain
B34_01744	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
B34_01747	COG3152	Membrane
B34_01748	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B34_01749	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B34_01750	COG1522	sequence-specific DNA binding
B34_01752	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B34_01753	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B34_01754	COG0454	-acetyltransferase
B34_01755	COG0517	IMP dehydrogenase activity
B34_01756	COG0123	including yeast histone deacetylase and acetoin utilization protein
B34_01757	COG1360	Flagellar Motor Protein
B34_01758	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
B34_01759	COG1609	Transcriptional regulator
B34_01760	COG1605	Chorismate mutase
B34_01760	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
B34_01763	COG3118	belongs to the thioredoxin family
B34_01764	COG4980	gas vesicle protein
B34_01765	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
B34_01766	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B34_01767	COG1674	ftsk spoiiie
B34_01768	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B34_01769	COG4848	Belongs to the UPF0354 family
B34_01770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B34_01772	COG1363	Peptidase, m42
B34_01773	COG5584	Small secreted protein
B34_01774	COG0281	malic enzyme
B34_01775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B34_01776	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B34_01778	COG0510	thiamine kinase activity
B34_01779	COG1523	belongs to the glycosyl hydrolase 13 family
B34_01780	COG1523	belongs to the glycosyl hydrolase 13 family
B34_01781	COG1597	lipid kinase activity
B34_01783	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
B34_01784	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B34_01786	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B34_01787	COG2252	PERMEase
B34_01788	COG1349	DNA-binding transcription factor activity
B34_01789	COG1187	pseudouridine synthase activity
B34_01790	COG2244	polysaccharide biosynthetic process
B34_01791	COG2081	HI0933 family
B34_01792	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B34_01794	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B34_01796	COG0457	Tetratricopeptide repeat
B34_01798	COG5578	integral membrane protein
B34_01799	COG0673	inositol 2-dehydrogenase activity
B34_01800	COG1653	transport
B34_01801	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
B34_01802	COG4209	transmembrane transport
B34_01803	COG2207	Transcriptional regulator
B34_01804	COG1653	transport
B34_01805	COG0395	ABC-type sugar transport system, permease component
B34_01806	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B34_01807	COG1073	alpha beta
B34_01809	COG0583	DNA-binding transcription factor activity
B34_01810	COG0346	lactoylglutathione lyase activity
B34_01811	COG0495	leucyl-tRNA aminoacylation
B34_01813	COG2814	Major facilitator Superfamily
B34_01815	COG2433	Pfam Transposase IS66
B34_01816	COG0577	efflux transmembrane transporter activity
B34_01817	COG1136	(ABC) transporter
B34_01819	COG1131	(ABC) transporter
B34_01820	COG1725	Transcriptional regulator
B34_01823	COG1242	4 iron, 4 sulfur cluster binding
B34_01824	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
B34_01825	COG1301	dicarboxylic acid transport
B34_01827	COG2267	carboxylic ester hydrolase activity
B34_01828	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B34_01829	COG0671	phosphoesterase, PA-phosphatase related
B34_01830	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B34_01830	COG0438	transferase activity, transferring glycosyl groups
B34_01831	COG0367	asparagine synthase
B34_01832	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B34_01833	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
B34_01836	COG1506	peptidase
B34_01837	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B34_01838	COG1116	anion transmembrane transporter activity
B34_01839	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B34_01840	COG0494	nUDIX hydrolase
B34_01842	COG4824	toxin secretion phage lysis holin
B34_01843	COG0783	Belongs to the Dps family
B34_01846	COG1854	S-ribosylhomocysteine lyase activity
B34_01847	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
B34_01848	COG0288	reversible hydration of carbon dioxide
B34_01849	COG0523	cobalamin synthesis protein
B34_01850	COG0803	Belongs to the bacterial solute-binding protein 9 family
B34_01851	COG0254	rRNA binding
B34_01852	COG1271	oxidase subunit
B34_01853	COG1294	oxidase, subunit
B34_01856	COG4948	Mandelate Racemase Muconate Lactonizing
B34_01857	COG0318	PFAM AMP-dependent synthetase and ligase
B34_01858	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
B34_01859	COG0596	Alpha beta hydrolase
B34_01860	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
B34_01861	COG1169	isochorismate synthase
B34_01862	COG1575	Belongs to the MenA family. Type 1 subfamily
B34_01863	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B34_01864	COG0058	SHG alpha-glucan phosphorylase activity
B34_01865	COG0297	glycogen (starch) synthase activity
B34_01866	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B34_01867	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B34_01868	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
B34_01893	COG1609	Transcriptional regulator
B34_01894	COG3859	Proton-coupled thiamine transporter YuaJ
B34_01895	COG3764	Sortase (surface protein transpeptidase)
B34_01898	COG0457	Tetratricopeptide repeat
B34_01900	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
B34_01901	COG0569	domain protein
B34_01902	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B34_01904	COG2318	DinB family
B34_01906	COG1454	alcohol dehydrogenase
B34_01908	COG1510	regulation of RNA biosynthetic process
B34_01910	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
B34_01911	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B34_01912	COG2140	Oxalate decarboxylase
B34_01920	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
B34_01923	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B34_01924	COG0726	polysaccharide deacetylase
B34_01925	COG1408	metallophosphoesterase
B34_01926	COG1968	undecaprenyl-diphosphatase activity
B34_01927	COG0628	permease
B34_01928	COG0673	inositol 2-dehydrogenase activity
B34_01929	COG0693	protein deglycase activity
B34_01930	COG0840	transmembrane signaling receptor activity
B34_01931	COG0840	transmembrane signaling receptor activity
B34_01932	COG0840	transmembrane signaling receptor activity
B34_01934	COG2070	2-Nitropropane dioxygenase
B34_01935	COG0432	Pfam Uncharacterised protein family UPF0047
B34_01936	COG0366	Alpha amylase catalytic
B34_01939	COG5297	Belongs to the glycosyl hydrolase family 6
B34_01940	COG1253	flavin adenine dinucleotide binding
B34_01941	COG2738	Putative neutral zinc metallopeptidase
B34_01944	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B34_01946	COG2323	membrane
B34_01947	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
B34_01949	COG0166	Belongs to the GPI family
B34_01950	COG1979	alcohol dehydrogenase
B34_01951	COG2155	Conserved Protein
B34_01952	COG1098	S1 RNA binding domain
B34_01953	COG0436	Aminotransferase
B34_01954	COG1522	sequence-specific DNA binding
B34_01955	COG2267	carboxylic ester hydrolase activity
B34_01958	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
B34_01959	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
B34_01962	COG5018	Exonuclease
B34_01963	COG2814	Major facilitator Superfamily
B34_01964	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B34_01965	COG3011	Protein conserved in bacteria
B34_01967	COG3290	protein histidine kinase activity
B34_01968	COG4565	transcriptional regulatory protein
B34_01969	COG1183	phosphatidylcholine synthase activity
B34_01970	COG0586	Pfam SNARE associated Golgi protein
B34_01971	COG0688	phosphatidylethanolamine metabolic process
B34_01972	COG3493	citrate carrier protein
B34_01974	COG2111	Na H antiporter
B34_01974	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B34_01975	COG2111	Na H antiporter
B34_01976	COG1006	Multisubunit Na H antiporter MnhC subunit
B34_01977	COG0651	ATP synthesis coupled electron transport
B34_01978	COG1863	multisubunit Na H antiporter MnhE subunit
B34_01979	COG2212	antiporter activity
B34_01980	COG1320	monovalent cation:proton antiporter activity
B34_01981	COG2050	protein possibly involved in aromatic compounds catabolism
B34_01982	COG2197	response regulator
B34_01983	COG4585	Histidine kinase
B34_01989	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
B34_01990	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
B34_01991	COG1335	isochorismatase
B34_01992	COG5506	Protein of unknown function (DUF1694)
B34_01995	COG0628	permease
B34_01996	COG1959	2 iron, 2 sulfur cluster binding
B34_01999	COG1418	mRNA catabolic process
B34_02000	COG1028	Short-chain dehydrogenase reductase Sdr
B34_02002	COG1511	domain protein
B34_02003	COG0433	COG0433 Predicted ATPase
B34_02003	COG1674	ftsk spoiiie
B34_02004	COG4499	WXG100 protein secretion system (Wss), protein YukC
B34_02005	COG5417	Belongs to the EsaB family
B34_02006	COG4842	Belongs to the WXG100 family
B34_02007	COG1115	amino acid carrier protein
B34_02008	COG2508	Transcriptional regulator
B34_02008	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
B34_02009	COG0686	Belongs to the AlaDH PNT family
B34_02011	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B34_02012	COG1268	BioY protein
B34_02013	COG2056	Na+-H+ antiporter family
B34_02014	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B34_02015	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
B34_02016	COG3584	3D domain protein
B34_02018	COG1252	NADH dehydrogenase
B34_02019	COG0492	ferredoxin-NADP+ reductase activity
B34_02022	COG0456	acetyltransferase
B34_02023	COG0316	Belongs to the HesB IscA family
B34_02024	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
B34_02025	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B34_02026	COG4844	belongs to the
B34_02027	COG1252	NADH dehydrogenase
B34_02028	COG5646	InterPro IPR014922
B34_02030	COG0457	Tetratricopeptide repeat
B34_02031	COG3479	Phenolic acid decarboxylase
B34_02033	COG4837	Protein of unknown function (DUF1462)
B34_02034	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
B34_02035	COG1506	peptidase
B34_02035	COG0823	Involved in the tonB-independent uptake of proteins
B34_02035	COG4946	Tricorn protease homolog
B34_02036	COG0083	homoserine kinase activity
B34_02037	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B34_02038	COG0460	homoserine dehydrogenase
B34_02040	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B34_02041	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B34_02042	COG0647	UMP catabolic process
B34_02043	COG2445	Protein of unknown function DUF86
B34_02044	COG4470	Protein conserved in bacteria
B34_02047	COG0739	heme binding
B34_02049	COG0733	neurotransmitter:sodium symporter activity
B34_02051	COG3377	Domain of unknown function (DUF1805)
B34_02052	COG0737	Belongs to the 5'-nucleotidase family
B34_02053	COG0730	response to heat
B34_02054	COG1801	Protein of unknown function DUF72
B34_02056	COG3226	Transcriptional regulator
B34_02058	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
B34_02059	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B34_02060	COG2508	Transcriptional regulator
B34_02061	COG2814	Major facilitator Superfamily
B34_02062	COG1288	antiporter activity
B34_02063	COG1288	antiporter activity
B34_02064	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B34_02065	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B34_02066	COG2356	endonuclease I
B34_02068	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B34_02072	COG0457	Tetratricopeptide repeat
B34_02073	COG0719	Fe-S assembly protein
B34_02074	COG0822	iron-sulfur transferase activity
B34_02075	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B34_02076	COG0719	Fe-S assembly protein
B34_02077	COG0396	ATPase activity
B34_02079	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B34_02080	COG1464	Belongs to the NlpA lipoprotein family
B34_02081	COG2011	ABC-type metal ion transport system permease component
B34_02082	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B34_02084	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B34_02085	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
B34_02087	COG0509	glycine decarboxylation via glycine cleavage system
B34_02088	COG1393	Belongs to the ArsC family
B34_02089	COG1960	acyl-CoA dehydrogenase activity
B34_02090	COG0183	Belongs to the thiolase family
B34_02091	COG1024	Enoyl-CoA hydratase
B34_02091	COG1250	3-hydroxyacyl-CoA dehydrogenase
B34_02094	COG5577	PFAM Coat F domain
B34_02097	COG1120	ATPase activity
B34_02098	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B34_02099	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B34_02100	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B34_02103	COG1686	Belongs to the peptidase S11 family
B34_02104	COG1028	Short-chain dehydrogenase reductase Sdr
B34_02105	COG0783	Belongs to the Dps family
B34_02106	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B34_02107	COG0745	RESPONSE REGULATOR receiver
B34_02108	COG2205	protein histidine kinase activity
B34_02108	COG2770	Histidine kinase
B34_02110	COG1309	transcriptional regulator
B34_02111	COG0114	fumarate hydratase activity
B34_02113	COG0697	spore germination
B34_02114	COG0814	amino acid
B34_02117	COG2197	response regulator
B34_02118	COG4585	Histidine kinase
B34_02119	COG4758	membrane
B34_02121	COG1842	Phage shock protein A
B34_02122	COG4758	membrane
B34_02123	COG4677	pectinesterase activity
B34_02124	COG2096	Adenosyltransferase
B34_02125	COG4221	oxidoreductase activity
B34_02126	COG1028	Short-chain dehydrogenase reductase Sdr
B34_02127	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
B34_02128	COG1454	alcohol dehydrogenase
B34_02129	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B34_02130	COG1120	ATPase activity
B34_02131	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B34_02132	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B34_02133	COG1802	Transcriptional regulator
B34_02134	COG1028	Short-chain dehydrogenase reductase Sdr
B34_02135	COG2258	MOSC domain
B34_02136	COG0583	DNA-binding transcription factor activity
B34_02138	COG2721	sulfolactate sulfo-lyase activity
B34_02139	COG0246	Mannitol dehydrogenase
B34_02140	COG1609	Transcriptional regulator
B34_02141	COG2211	Major facilitator Superfamily
B34_02142	COG1904	glucuronate isomerase
B34_02143	COG2205	protein histidine kinase activity
B34_02144	COG0745	RESPONSE REGULATOR receiver
B34_02145	COG1120	ATPase activity
B34_02146	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B34_02147	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B34_02148	COG0531	amino acid
B34_02149	COG1988	membrane-bound metal-dependent
B34_02150	COG1368	sulfuric ester hydrolase activity
B34_02151	COG2814	Major facilitator Superfamily
B34_02152	COG0656	L-ascorbic acid biosynthetic process
B34_02153	COG1940	carbohydrate kinase activity
B34_02154	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B34_02156	COG3973	AAA domain
B34_02157	COG2860	membrane
B34_02158	COG0456	acetyltransferase
B34_02158	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
B34_02160	COG0456	acetyltransferase
B34_02161	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
B34_02162	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B34_02163	COG2217	Heavy metal translocating P-type atpase
B34_02164	COG1653	transport
B34_02165	COG1175	transmembrane transport
B34_02166	COG0395	ABC-type sugar transport system, permease component
B34_02167	COG1501	Belongs to the glycosyl hydrolase 31 family
B34_02168	COG1472	Belongs to the glycosyl hydrolase 3 family
B34_02169	COG1121	(ABC) transporter
B34_02170	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B34_02171	COG0803	Belongs to the bacterial solute-binding protein 9 family
B34_02176	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B34_02176	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B34_02176	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B34_02180	COG2217	Heavy metal translocating P-type atpase
B34_02181	COG2608	mercury ion transmembrane transporter activity
B34_02182	COG1937	Protein conserved in bacteria
B34_02183	COG0693	protein deglycase activity
B34_02184	COG1349	DNA-binding transcription factor activity
B34_02185	COG1070	Carbohydrate kinase
B34_02186	COG4952	isomerase
B34_02188	COG3347	Dehydrogenase
B34_02188	COG1028	Short-chain dehydrogenase reductase Sdr
B34_02189	COG2814	Major facilitator Superfamily
B34_02190	COG2814	Major facilitator Superfamily
B34_02192	COG2124	cytochrome p450
B34_02194	COG1846	Transcriptional regulator
B34_02197	COG0673	inositol 2-dehydrogenase activity
B34_02198	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B34_02202	COG1191	sigma factor activity
B34_02204	COG2140	Oxalate decarboxylase
B34_02219	COG5444	nuclease activity
B34_02228	COG1705	Flagellar rod assembly protein muramidase FlgJ
B34_02230	COG3953	SLT domain
B34_02230	COG5280	Phage tail tape measure protein TP901
B34_02242	COG4626	Terminase
B34_02242	COG1802	Transcriptional regulator
B34_02276	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
B34_02277	COG0557	exoribonuclease II activity
B34_02278	COG1647	Serine aminopeptidase, S33
B34_02279	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B34_02280	COG2002	toxin-antitoxin pair type II binding
B34_02281	COG1476	TRANSCRIPTIONal
B34_02282	COG1396	sequence-specific DNA binding
B34_02283	COG1396	sequence-specific DNA binding
B34_02284	COG1174	glycine betaine transport
B34_02285	COG1732	Glycine betaine
B34_02286	COG1174	glycine betaine transport
B34_02287	COG0517	IMP dehydrogenase activity
B34_02287	COG1125	glycine betaine transport
B34_02288	COG1510	regulation of RNA biosynthetic process
B34_02289	COG2095	MarC family integral membrane protein
B34_02290	COG2095	MarC family integral membrane protein
B34_02291	COG3064	Membrane
B34_02292	COG4640	response to antibiotic
B34_02294	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B34_02296	COG0693	protein deglycase activity
B34_02297	COG0148	phosphopyruvate hydratase activity
B34_02298	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
B34_02299	COG0149	triose-phosphate isomerase activity
B34_02300	COG0126	phosphoglycerate kinase activity
B34_02301	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B34_02302	COG2390	Transcriptional regulator
B34_02303	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B34_02304	COG1113	amino acid transport
B34_02308	COG1556	Lactate utilization protein
B34_02309	COG1139	Iron-sulfur cluster binding protein
B34_02310	COG0247	lactate metabolic process
B34_02311	COG2186	Transcriptional regulator
B34_02312	COG1620	l-lactate permease
B34_02313	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
B34_02315	COG5039	Polysaccharide pyruvyl transferase
B34_02316	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B34_02317	COG0110	maltose O-acetyltransferase activity
B34_02318	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B34_02319	COG2244	polysaccharide biosynthetic process
B34_02320	COG1216	Glycosyl transferase, family 2
B34_02321	COG5039	Polysaccharide pyruvyl transferase
B34_02322	COG1216	Glycosyl transferase, family 2
B34_02324	COG0438	transferase activity, transferring glycosyl groups
B34_02325	COG1215	transferase activity, transferring glycosyl groups
B34_02326	COG0438	transferase activity, transferring glycosyl groups
B34_02327	COG1086	Polysaccharide biosynthesis protein
B34_02328	COG0489	protein tyrosine kinase activity
B34_02329	COG3944	biosynthesis protein
B34_02330	COG1396	sequence-specific DNA binding
B34_02331	COG2249	NAD(P)H dehydrogenase (quinone) activity
B34_02333	COG2271	Major facilitator Superfamily
B34_02335	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
B34_02338	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B34_02340	COG1733	regulation of RNA biosynthetic process
B34_02341	COG1902	pentaerythritol trinitrate reductase activity
B34_02342	COG1621	beta-fructofuranosidase activity
B34_02343	COG1621	beta-fructofuranosidase activity
B34_02346	COG0740	serine-type endopeptidase activity
B34_02347	COG1611	Belongs to the LOG family
B34_02348	COG1694	Mazg nucleotide pyrophosphohydrolase
B34_02349	COG1078	dGTPase activity
B34_02350	COG0659	secondary active sulfate transmembrane transporter activity
B34_02351	COG0288	reversible hydration of carbon dioxide
B34_02352	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B34_02353	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B34_02354	COG0640	Transcriptional regulator
B34_02356	COG2732	(Barnase) inhibitor
B34_02357	COG2162	N-hydroxyarylamine O-acetyltransferase activity
B34_02358	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B34_02359	COG1481	regulation of sporulation
B34_02360	COG0391	Required for morphogenesis under gluconeogenic growth conditions
B34_02361	COG1660	Displays ATPase and GTPase activities
B34_02362	COG1051	belongs to the nudix hydrolase family
B34_02363	COG0492	ferredoxin-NADP+ reductase activity
B34_02364	COG0457	Tetratricopeptide repeat
B34_02366	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
B34_02366	COG0140	phosphoribosyl-ATP diphosphatase activity
B34_02367	COG0107	imidazoleglycerol-phosphate synthase activity
B34_02368	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
B34_02369	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B34_02370	COG0131	Imidazoleglycerol-phosphate dehydratase
B34_02371	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B34_02372	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B34_02373	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
B34_02374	COG4990	cell redox homeostasis
B34_02375	COG5297	Belongs to the glycosyl hydrolase family 6
B34_02376	COG0110	maltose O-acetyltransferase activity
B34_02377	COG0546	phosphoglycolate phosphatase activity
B34_02378	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
B34_02379	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
B34_02380	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
B34_02381	COG1846	Transcriptional regulator
B34_02382	COG2814	Major facilitator Superfamily
B34_02383	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B34_02384	COG1950	PFAM Membrane protein of
B34_02385	COG1983	PspC domain protein
B34_02386	COG3595	metallopeptidase activity
B34_02390	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B34_02391	COG0556	nucleotide-excision repair
B34_02392	COG4897	Protein conserved in bacteria
B34_02394	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B34_02396	COG3409	Peptidoglycan-binding domain 1 protein
B34_02396	COG0793	Belongs to the peptidase S41A family
B34_02397	COG0473	3-isopropylmalate dehydrogenase activity
B34_02398	COG3883	PFAM NLP P60 protein
B34_02398	COG0791	NLP P60 protein
B34_02399	COG2177	Part of the ABC transporter FtsEX involved in
B34_02400	COG2884	Cell division ATP-binding protein ftsE
B34_02401	COG2010	Cytochrome c
B34_02402	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B34_02403	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
B34_02404	COG0653	protein targeting
B34_02405	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
B34_02408	COG1516	flagellar protein fliS
B34_02409	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
B34_02410	COG1334	flagellar protein FlaG
B34_02411	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B34_02412	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
B34_02413	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
B34_02415	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B34_02416	COG1256	bacterial-type flagellum assembly
B34_02416	COG4786	Flagellar basal body rod
B34_02417	COG3418	PFAM FlgN family protein
B34_02418	COG2747	anti-sigma28 factor FlgM
B34_02421	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
B34_02422	COG1307	EDD domain protein, DegV family
B34_02423	COG2197	response regulator
B34_02424	COG4585	Histidine kinase
B34_02425	COG1739	Uncharacterized protein family UPF0029
B34_02426	COG1316	TRANSCRIPTIONal
B34_02428	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B34_02429	COG0438	transferase activity, transferring glycosyl groups
B34_02430	COG1215	transferase activity, transferring glycosyl groups
B34_02431	COG3206	protein involved in exopolysaccharide biosynthesis
B34_02432	COG3307	-O-antigen
B34_02433	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B34_02434	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B34_02435	COG0438	transferase activity, transferring glycosyl groups
B34_02435	COG0297	glycogen (starch) synthase activity
B34_02436	COG2244	polysaccharide biosynthetic process
B34_02438	COG2247	cell wall binding repeat
B34_02438	COG0860	N-Acetylmuramoyl-L-alanine amidase
B34_02439	COG2385	sporulation resulting in formation of a cellular spore
B34_02439	COG2247	cell wall binding repeat
B34_02441	COG1316	TRANSCRIPTIONal
B34_02442	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
B34_02443	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B34_02444	COG1134	teichoic acid transport
B34_02445	COG1682	transport, permease protein
B34_02446	COG0438	transferase activity, transferring glycosyl groups
B34_02448	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B34_02452	COG0463	Glycosyl transferase, family 2
B34_02452	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B34_02453	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B34_02454	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
B34_02455	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
B34_02456	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B34_02457	COG4193	domain, Protein
B34_02458	COG1482	cell wall glycoprotein biosynthetic process
B34_02462	COG0800	Aldolase
B34_02463	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B34_02464	COG1609	Transcriptional regulator
B34_02465	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
B34_02466	COG1028	Short-chain dehydrogenase reductase Sdr
B34_02467	COG1063	alcohol dehydrogenase
B34_02469	COG2814	Major facilitator Superfamily
B34_02470	COG1316	TRANSCRIPTIONal
B34_02471	COG0561	phosphatase activity
B34_02472	COG0791	NLP P60 protein
B34_02474	COG2843	Capsule synthesis protein
B34_02476	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B34_02477	COG1609	Transcriptional regulator
B34_02478	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B34_02479	COG1869	D-ribose catabolic process
B34_02480	COG1129	ABC transporter
B34_02481	COG1172	Belongs to the binding-protein-dependent transport system permease family
B34_02482	COG1879	ABC-type sugar transport system periplasmic component
B34_02483	COG3527	Alpha-acetolactate decarboxylase
B34_02484	COG0028	Belongs to the TPP enzyme family
B34_02485	COG0583	DNA-binding transcription factor activity
B34_02486	COG2801	Transposase and inactivated derivatives
B34_02488	COG0405	Gamma-glutamyltransferase
B34_02489	COG1522	sequence-specific DNA binding
B34_02490	COG2059	Chromate
B34_02491	COG2059	Chromate
B34_02492	COG4464	protein tyrosine phosphatase activity
B34_02493	COG3944	biosynthesis protein
B34_02495	COG4715	Zinc finger, swim domain protein
B34_02496	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B34_02498	COG0561	phosphatase activity
B34_02499	COG1349	DNA-binding transcription factor activity
B34_02501	COG1028	Short-chain dehydrogenase reductase Sdr
B34_02503	COG3732	PTS system glucitol sorbitol-specific
B34_02507	COG0629	single-stranded DNA binding
B34_02510	COG1970	mechanosensitive ion channel activity
B34_02511	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B34_02512	COG4786	Flagellar basal body rod
B34_02513	COG4786	Flagellar basal body rod
B34_02514	COG1077	Cell shape determining protein MreB Mrl
B34_02515	COG1609	Transcriptional regulator
B34_02516	COG1846	Transcriptional regulator
B34_02517	COG2814	Major facilitator Superfamily
B34_02518	COG0671	phosphoesterase, PA-phosphatase related
B34_02519	COG1227	inorganic diphosphatase activity
B34_02520	COG3546	catalase activity
B34_02521	COG3361	conserved protein (COG2071)
B34_02522	COG0517	IMP dehydrogenase activity
B34_02523	COG0598	Magnesium transport protein CorA
B34_02524	COG1253	flavin adenine dinucleotide binding
B34_02525	COG0004	ammonium transporteR
B34_02526	COG0347	Belongs to the P(II) protein family
B34_02527	COG0740	serine-type endopeptidase activity
B34_02529	COG0739	heme binding
B34_02530	COG1247	-acetyltransferase
B34_02532	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B34_02533	COG0477	Major facilitator Superfamily
B34_02534	COG3251	PFAM MbtH domain protein
B34_02535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B34_02536	COG3433	isochorismatase activity
B34_02536	COG1535	isochorismatase
B34_02537	COG1021	2,3-dihydroxybenzoate-AMP ligase
B34_02538	COG1169	isochorismate synthase
B34_02539	COG1028	Short-chain dehydrogenase reductase Sdr
B34_02540	COG2819	hydrolase of the alpha beta superfamily
B34_02541	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B34_02542	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B34_02543	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B34_02544	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B34_02544	COG2207	Transcriptional regulator
B34_02546	COG2910	NAD(P)H-binding
B34_02547	COG1959	2 iron, 2 sulfur cluster binding
B34_02549	COG1994	Peptidase M50
B34_02550	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B34_02551	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
B34_02553	COG3383	formate dehydrogenase (NAD+) activity
B34_02554	COG2304	oxidoreductase activity
B34_02555	COG2304	oxidoreductase activity
B34_02556	COG2385	sporulation resulting in formation of a cellular spore
B34_02557	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B34_02559	COG4836	Membrane
B34_02560	COG0355	proton-transporting ATP synthase activity, rotational mechanism
B34_02561	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
B34_02562	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
B34_02563	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
B34_02564	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B34_02565	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B34_02566	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B34_02569	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
B34_02570	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B34_02571	COG4475	Protein of unknown function (DUF436)
B34_02572	COG0698	ribose 5-phosphate isomerase
B34_02573	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B34_02574	COG1971	Probably functions as a manganese efflux pump
B34_02575	COG0009	L-threonylcarbamoyladenylate synthase
B34_02576	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
B34_02578	COG0738	Major facilitator superfamily
B34_02579	COG0673	inositol 2-dehydrogenase activity
B34_02580	COG0561	phosphatase activity
B34_02581	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B34_02582	COG1609	Transcriptional regulator
B34_02583	COG2890	protein-(glutamine-N5) methyltransferase activity
B34_02584	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
B34_02585	COG0346	lactoylglutathione lyase activity
B34_02586	COG0789	Transcriptional regulator
B34_02587	COG0679	Auxin Efflux Carrier
B34_02588	COG0281	malic enzyme
B34_02589	COG1435	thymidine kinase activity
B34_02590	COG0254	rRNA binding
B34_02591	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
B34_02592	COG1494	fructose-1,6-bisphosphatase
B34_02593	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B34_02594	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B34_02595	COG0191	fructose-bisphosphate aldolase activity
B34_02596	COG2204	response regulator
B34_02597	COG4821	SIS domain
B34_02600	COG2801	Transposase and inactivated derivatives
B34_02601	COG0504	CTP synthase activity
B34_02602	COG3343	RNA polymerase activity
B34_02603	COG1960	acyl-CoA dehydrogenase activity
B34_02604	COG1960	acyl-CoA dehydrogenase activity
B34_02605	COG1250	3-hydroxyacyl-CoA dehydrogenase
B34_02606	COG0183	Belongs to the thiolase family
B34_02607	COG2181	nitrate reductase activity
B34_02607	COG0247	lactate metabolic process
B34_02608	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B34_02610	COG0018	arginyl-trna synthetase
B34_02611	COG4506	Protein conserved in bacteria
B34_02612	COG0010	Belongs to the arginase family
B34_02613	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
B34_02616	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B34_02618	COG1994	Peptidase M50
B34_02619	COG1942	4-Oxalocrotonate Tautomerase
B34_02621	COG3465	dGTPase activity
B34_02622	COG1078	dGTPase activity
B34_02623	COG4844	belongs to the
B34_02628	COG2814	Major facilitator Superfamily
B34_02633	COG1414	Transcriptional regulator
B34_02635	COG0280	phosphate acetyltransferase
B34_02638	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B34_02642	COG1131	(ABC) transporter
B34_02645	COG2363	Small membrane protein
B34_02646	COG2233	PERMEase
B34_02648	COG1012	belongs to the aldehyde dehydrogenase family
B34_02649	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
B34_02650	COG1216	Glycosyl transferase, family 2
B34_02651	COG0351	phosphomethylpyrimidine kinase
B34_02653	COG1621	beta-fructofuranosidase activity
B34_02654	COG1263	PTS System
B34_02654	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B34_02655	COG3711	transcriptional antiterminator
B34_02658	COG1404	Belongs to the peptidase S8 family
B34_02660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B34_02662	COG0778	Nitroreductase
B34_02663	COG1473	amidohydrolase
B34_02664	COG0772	Belongs to the SEDS family
B34_02665	COG0772	Belongs to the SEDS family
B34_02670	COG0456	acetyltransferase
B34_02678	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B34_02680	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B34_02681	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B34_02682	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B34_02686	COG0655	NAD(P)H dehydrogenase (quinone) activity
B34_02687	COG3162	membrane
B34_02688	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B34_02689	COG1070	Carbohydrate kinase
B34_02690	COG2115	Belongs to the xylose isomerase family
B34_02692	COG0352	thiamine-phosphate diphosphorylase activity
B34_02693	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
B34_02694	COG0583	DNA-binding transcription factor activity
B34_02697	COG1380	Effector of murein hydrolase LrgA
B34_02698	COG1346	cytolysis
B34_02700	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B34_02701	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B34_02702	COG0346	lactoylglutathione lyase activity
B34_02703	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B34_02704	COG1442	glycosyl transferase family 8
B34_02707	COG4585	Histidine kinase
B34_02708	COG2197	response regulator
B34_02709	COG2409	Drug exporters of the RND superfamily
B34_02710	COG5522	Integral membrane protein (intg_mem_TP0381)
B34_02711	COG2271	Major facilitator Superfamily
B34_02712	COG4948	Mandelate Racemase Muconate Lactonizing
B34_02713	COG0800	Aldolase
B34_02714	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B34_02716	COG2234	aminopeptidase activity
B34_02717	COG0477	Major facilitator Superfamily
B34_02719	COG2357	RelA SpoT domain protein
B34_02722	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B34_02723	COG1696	Membrane protein involved in D-alanine export
B34_02724	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B34_02725	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
B34_02726	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B34_02727	COG2814	Major facilitator Superfamily
B34_02728	COG1486	melibiose metabolic process
B34_02729	COG1447	Phosphotransferase system cellobiose-specific component IIA
B34_02730	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B34_02731	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B34_02732	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B34_02732	COG3711	transcriptional antiterminator
B34_02734	COG2094	Belongs to the DNA glycosylase MPG family
B34_02736	COG0372	Belongs to the citrate synthase family
B34_02737	COG2079	MmgE PrpD family protein
B34_02738	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
B34_02741	COG1132	(ABC) transporter
B34_02742	COG2755	lipolytic protein G-D-S-L family
B34_02745	COG2814	Major facilitator Superfamily
B34_02746	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
B34_02747	COG1131	(ABC) transporter
B34_02751	COG1595	DNA-templated transcription, initiation
B34_02752	COG2814	Major facilitator Superfamily
B34_02753	COG0753	catalase activity
B34_02754	COG0753	catalase activity
B34_02755	COG0735	belongs to the Fur family
B34_02757	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
B34_02758	COG1131	(ABC) transporter
B34_02761	COG1131	(ABC) transporter
B34_02771	COG3866	Pectate lyase
B34_02772	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
B34_02773	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
B34_02774	COG4988	ABC transporter
B34_02775	COG1294	oxidase, subunit
B34_02776	COG1271	oxidase subunit
B34_02777	COG2116	formate transmembrane transporter activity
B34_02779	COG0281	malic enzyme
B34_02780	COG1757	Na H antiporter
B34_02781	COG1027	Aspartate ammonia-lyase
B34_02782	COG0252	asparaginase activity
B34_02783	COG1396	sequence-specific DNA binding
B34_02784	COG2706	6-phosphogluconolactonase activity
B34_02785	COG0745	RESPONSE REGULATOR receiver
B34_02786	COG2205	protein histidine kinase activity
B34_02787	COG1136	(ABC) transporter
B34_02788	COG0577	efflux transmembrane transporter activity
B34_02789	COG5294	Protein conserved in bacteria
B34_02792	COG0726	polysaccharide deacetylase
B34_02793	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B34_02794	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B34_02795	COG1215	transferase activity, transferring glycosyl groups
B34_02796	COG3493	citrate carrier protein
B34_02797	COG0584	glycerophosphoryl diester phosphodiesterase
B34_02800	COG1368	sulfuric ester hydrolase activity
B34_02802	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B34_02804	COG2235	arginine
B34_02805	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B34_02807	COG0549	Belongs to the carbamate kinase family
B34_02809	COG2723	6-phospho-beta-galactosidase activity
B34_02810	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B34_02812	COG1595	DNA-templated transcription, initiation
B34_02817	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B34_02818	COG2195	Cleaves the N-terminal amino acid of tripeptides
B34_02819	COG1621	beta-fructofuranosidase activity
B34_02820	COG2223	nitrite transmembrane transporter activity
B34_02821	COG0395	ABC-type sugar transport system, permease component
B34_02822	COG1175	transmembrane transport
B34_02824	COG1609	Transcriptional regulator
B34_02828	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B34_02829	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
B34_02830	COG0463	Glycosyl transferase, family 2
B34_02831	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B34_02833	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B34_02834	COG0693	protein deglycase activity
B34_02834	COG0753	catalase activity
B34_02836	COG2723	6-phospho-beta-galactosidase activity
B34_02837	COG2190	(PTS) system
B34_02837	COG1263	PTS System
B34_02837	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B34_02838	COG3711	transcriptional antiterminator
B34_02839	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
B34_02840	COG1122	ATPase activity
B34_02841	COG4721	ABC-type cobalt transport system, permease component
B34_02842	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
B34_02844	COG2224	Isocitrate lyase
B34_02845	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B34_02847	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
B34_02848	COG0577	efflux transmembrane transporter activity
B34_02849	COG1136	(ABC) transporter
B34_02850	COG2205	protein histidine kinase activity
B34_02851	COG0745	RESPONSE REGULATOR receiver
B34_02852	COG2723	6-phospho-beta-galactosidase activity
B34_02853	COG1263	PTS System
B34_02853	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B34_02853	COG2190	(PTS) system
B34_02855	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
B34_02858	COG3507	Belongs to the glycosyl hydrolase 43 family
B34_02859	COG0513	Belongs to the DEAD box helicase family
B34_02865	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
B34_02866	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B34_02867	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
B34_02868	COG2390	Transcriptional regulator
B34_02870	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
B34_02871	COG3706	GGDEF domain
B34_02872	COG5298	Protein conserved in bacteria
B34_02873	COG1215	transferase activity, transferring glycosyl groups
B34_02874	COG1215	transferase activity, transferring glycosyl groups
B34_02876	COG3977	Valine--pyruvate aminotransferase
B34_02879	COG1181	Belongs to the D-alanine--D-alanine ligase family
B34_02881	COG0191	fructose-bisphosphate aldolase activity
B34_02882	COG1082	Xylose isomerase domain protein TIM barrel
B34_02883	COG1082	Xylose isomerase domain protein TIM barrel
B34_02884	COG0673	inositol 2-dehydrogenase activity
B34_02885	COG2814	Major facilitator Superfamily
B34_02886	COG1082	Xylose isomerase domain protein TIM barrel
B34_02887	COG3962	Belongs to the TPP enzyme family
B34_02888	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B34_02889	COG3718	enzyme involved in inositol metabolism
B34_02890	COG1012	belongs to the aldehyde dehydrogenase family
B34_02891	COG1349	DNA-binding transcription factor activity
B34_02892	COG0667	Aldo Keto reductase
B34_02893	COG0584	glycerophosphoryl diester phosphodiesterase
B34_02894	COG2271	Major facilitator Superfamily
B34_02895	COG0326	Molecular chaperone. Has ATPase activity
B34_02896	COG0488	(ABC) transporter
B34_02897	COG0561	phosphatase activity
B34_02901	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B34_02906	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
B34_02907	COG0577	efflux transmembrane transporter activity
B34_02908	COG1136	(ABC) transporter
B34_02909	COG2205	protein histidine kinase activity
B34_02910	COG0745	RESPONSE REGULATOR receiver
B34_02912	COG0840	transmembrane signaling receptor activity
B34_02912	COG5278	phosphoserine phosphatase activity
B34_02913	COG1115	amino acid carrier protein
B34_02914	COG0686	Belongs to the AlaDH PNT family
B34_02915	COG3867	Arabinogalactan endo-beta-1,4-galactanase
B34_02916	COG1874	Beta-galactosidase
B34_02917	COG3833	ABC-type maltose transport systems, permease component
B34_02918	COG1175	transmembrane transport
B34_02919	COG2182	Extracellular solute-binding protein
B34_02920	COG1609	Transcriptional regulator
B34_02922	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B34_02923	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
B34_02924	COG1940	carbohydrate kinase activity
B34_02929	COG1012	belongs to the aldehyde dehydrogenase family
B34_02929	COG1454	alcohol dehydrogenase
B34_02930	COG0450	alkyl hydroperoxide reductase
B34_02931	COG3634	alkyl hydroperoxide reductase activity
B34_02936	COG1131	(ABC) transporter
B34_02937	COG0842	Transport permease protein
B34_02938	COG4585	Histidine kinase
B34_02939	COG4585	Histidine kinase
B34_02940	COG2197	response regulator
B34_02946	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
B34_02949	COG0456	acetyltransferase
B34_02952	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B34_02953	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
B34_02954	COG4853	Protein conserved in bacteria
B34_02955	COG4863	YycH protein
B34_02956	COG5002	protein histidine kinase activity
B34_02957	COG0745	RESPONSE REGULATOR receiver
B34_02962	COG1051	belongs to the nudix hydrolase family
B34_02963	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
B34_02965	COG0305	Participates in initiation and elongation during chromosome replication
B34_02968	COG3093	addiction module antidote protein HigA
B34_02969	COG2807	transmembrane transport
B34_02970	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B34_02971	COG0363	glucosamine-6-phosphate deaminase activity
B34_02973	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
B34_02974	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B34_02974	COG1263	PTS System
B34_02975	COG0359	binds to the 23S rRNA
B34_02976	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
B34_02977	COG4241	membrane
B34_02978	COG5577	PFAM Coat F domain
B34_02979	COG0589	response to stress
B34_02980	COG0659	secondary active sulfate transmembrane transporter activity
B34_02981	COG2271	Major facilitator Superfamily
B34_02982	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B34_02983	COG0629	single-stranded DNA binding
B34_02984	COG0360	Binds together with S18 to 16S ribosomal RNA
B34_02985	COG0012	GTP binding
B34_02986	COG4481	Protein conserved in bacteria
B34_02987	COG3949	Membrane
B34_02989	COG1475	DNA binding
B34_02990	COG1192	Involved in chromosome partitioning
B34_02991	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B34_02993	COG1475	DNA binding
B34_02994	COG0357	Ribosomal RNA small subunit methyltransferase G
B34_02995	COG0445	tRNA wobble uridine modification
B34_02996	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
B34_02997	COG1847	R3H domain protein
B34_02998	COG0706	membrane insertase activity
B34_02999	COG0594	ribonuclease P activity
B34_03000	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
B34_03001	COG0592	DNA-directed DNA polymerase activity
B34_03002	COG2501	S4 domain
B34_03003	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B34_03004	COG0187	DNA topoisomerase II activity
B34_03005	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B34_03012	COG0517	IMP dehydrogenase activity
B34_03012	COG0516	GMP reductase activity
B34_03013	COG1686	Belongs to the peptidase S11 family
B34_03014	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
B34_03015	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
B34_03016	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B34_03017	COG1929	Belongs to the glycerate kinase type-1 family
B34_03018	COG2610	gluconate transmembrane transporter activity
B34_03019	COG3835	regulator
B34_03022	COG1428	Deoxynucleoside kinase
B34_03023	COG1428	Deoxynucleoside kinase
B34_03024	COG3858	chitin binding
B34_03024	COG1388	LysM domain
B34_03025	COG1335	isochorismatase
B34_03026	COG0590	tRNA wobble adenosine to inosine editing
B34_03027	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B34_03028	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
B34_03029	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B34_03038	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
B34_03039	COG3853	Toxic anion resistance protein (TelA)
B34_03040	COG1982	Orn Lys Arg decarboxylase major
B34_03041	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B34_03042	COG3870	Protein conserved in bacteria
B34_03043	COG1728	Protein conserved in bacteria
B34_03044	COG0470	DNA polymerase III
B34_03045	COG1774	PSP1 C-terminal conserved region
B34_03046	COG4467	Involved in initiation control of chromosome replication
B34_03047	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
B34_03048	COG2827	Endonuclease containing a URI domain
B34_03049	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
B34_03050	COG2002	toxin-antitoxin pair type II binding
B34_03051	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B34_03051	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B34_03052	COG0084	hydrolase, TatD family'
B34_03053	COG3583	domain protein
B34_03053	COG3584	3D domain protein
B34_03054	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
B34_03055	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B34_03057	COG4466	Protein conserved in bacteria
B34_03060	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
B34_03061	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B34_03062	COG0251	oxidation-reduction process
B34_03063	COG2088	sporulation resulting in formation of a cellular spore
B34_03064	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B34_03065	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B34_03066	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
B34_03067	COG0193	aminoacyl-tRNA hydrolase activity
B34_03069	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B34_03070	COG2002	toxin-antitoxin pair type II binding
B34_03071	COG2244	polysaccharide biosynthetic process
B34_03072	COG3956	TIGRFAM MazG family protein
B34_03073	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
B34_03076	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
B34_03077	COG1098	S1 RNA binding domain
B34_03080	COG2208	phosphoserine phosphatase activity
B34_03081	COG2304	oxidoreductase activity
B34_03082	COG0515	serine threonine protein kinase
B34_03083	COG0037	tRNA processing
B34_03085	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B34_03086	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
B34_03087	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
B34_03088	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B34_03089	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B34_03090	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B34_03091	COG0512	Glutamine amidotransferase of anthranilate synthase
B34_03092	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B34_03093	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B34_03094	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B34_03095	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B34_03096	COG1396	sequence-specific DNA binding
B34_03097	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B34_03098	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
B34_03114	COG4463	regulation of RNA biosynthetic process
B34_03115	COG3880	PFAM UvrB UvrC protein
B34_03116	COG3869	Catalyzes the specific phosphorylation of arginine residues in
B34_03117	COG0542	response to heat
B34_03118	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
B34_03119	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
B34_03120	COG4956	integral membrane protein (PIN domain superfamily)
B34_03121	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
B34_03122	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
B34_03123	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B34_03124	COG1045	serine acetyltransferase
B34_03125	COG0215	cysteine-tRNA ligase activity
B34_03126	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
B34_03127	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B34_03128	COG3688	RNA-binding protein containing a PIN domain
B34_03131	COG0250	Participates in transcription elongation, termination and antitermination
B34_03132	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
B34_03133	COG0081	regulation of translation
B34_03134	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
B34_03135	COG0222	ribosome binding
B34_03136	COG2813	Specifically methylates the guanine in position
B34_03137	COG0085	RNA polymerase activity
B34_03138	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
B34_03139	COG1358	cellular component organization or biogenesis
B34_03140	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
B34_03141	COG0049	tRNA binding
B34_03142	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B34_03143	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B34_03144	COG0051	transcription antitermination factor activity, RNA binding
B34_03145	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
B34_03146	COG0088	Forms part of the polypeptide exit tunnel
B34_03147	COG0089	rRNA binding
B34_03148	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
B34_03149	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
B34_03150	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
B34_03151	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
B34_03152	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
B34_03153	COG0255	Belongs to the universal ribosomal protein uL29 family
B34_03154	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
B34_03155	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
B34_03156	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
B34_03157	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B34_03158	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B34_03159	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
B34_03160	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
B34_03161	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
B34_03162	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
B34_03163	COG1841	ribosomal large subunit assembly
B34_03164	COG0200	Binds to the 23S rRNA
B34_03165	COG0201	protein transport
B34_03166	COG0563	adenylate kinase activity
B34_03167	COG0024	Methionine aminopeptidase
B34_03168	COG2163	COG2163 Ribosomal protein L14E L6E L27E
B34_03169	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
B34_03170	COG0257	Belongs to the bacterial ribosomal protein bL36 family
B34_03171	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B34_03172	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
B34_03173	COG0202	RNA polymerase activity
B34_03174	COG0203	ribosomal protein L17
B34_03175	COG1122	ATPase activity
B34_03176	COG1122	ATPase activity
B34_03177	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
B34_03178	COG0101	tRNA pseudouridine synthase activity
B34_03179	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
B34_03180	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B34_03181	COG2318	DinB family
B34_03185	COG1131	(ABC) transporter
B34_03191	COG2274	protein secretion by the type I secretion system
B34_03196	COG3290	protein histidine kinase activity
B34_03201	COG0860	N-Acetylmuramoyl-L-alanine amidase
B34_03202	COG0489	protein tyrosine kinase activity
B34_03204	COG2194	sulfuric ester hydrolase activity
B34_03205	COG0726	polysaccharide deacetylase
B34_03212	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B34_03214	COG0385	Bile acid
B34_03217	COG3876	Protein conserved in bacteria
B34_03218	COG1472	Belongs to the glycosyl hydrolase 3 family
B34_03219	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B34_03220	COG1263	PTS System
B34_03220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B34_03221	COG1737	Transcriptional regulator
B34_03222	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
B34_03223	COG1683	Conserved Protein
B34_03230	COG1595	DNA-templated transcription, initiation
B34_03231	COG5662	AntiSigma factor
B34_03232	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
B34_03233	COG4856	YbbR-like protein
B34_03234	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B34_03235	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B34_03239	COG1725	Transcriptional regulator
B34_03240	COG0640	Transcriptional regulator
B34_03241	COG2814	Major facilitator Superfamily
B34_03243	COG1132	(ABC) transporter
B34_03244	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B34_03249	COG1011	Hydrolase
B34_03250	COG1113	amino acid transport
B34_03251	COG2851	Citrate transporter
B34_03252	COG3181	Tripartite tricarboxylate transporter family receptor
B34_03253	COG4565	transcriptional regulatory protein
B34_03254	COG3290	protein histidine kinase activity
B34_03257	COG2211	Major facilitator Superfamily
B34_03261	COG1331	Highly conserved protein containing a thioredoxin domain
B34_03262	COG0477	Major facilitator Superfamily
B34_03266	COG1283	sodium-dependent phosphate transmembrane transporter activity
B34_03267	COG4682	membrane
B34_03272	COG0697	spore germination
B34_03273	COG1917	Cupin 2, conserved barrel domain protein
B34_03273	COG2207	Transcriptional regulator
B34_03277	COG0371	Dehydrogenase
B34_03278	COG0840	transmembrane signaling receptor activity
B34_03279	COG4213	ABC transporter substrate-binding protein
B34_03282	COG4257	antibiotic catabolic process
B34_03284	COG0833	amino acid
B34_03285	COG2040	homocysteine
B34_03287	COG2190	(PTS) system
B34_03287	COG1263	PTS System
B34_03287	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B34_03288	COG0789	Transcriptional regulator
B34_03289	COG2323	membrane
B34_03291	COG2205	protein histidine kinase activity
B34_03292	COG1115	amino acid carrier protein
B34_03293	COG2066	Belongs to the glutaminase family
B34_03294	COG4191	Histidine kinase
B34_03295	COG0784	Response regulator, receiver
B34_03300	COG3540	Alkaline phosphatase
B34_03301	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B34_03302	COG0805	protein transport
B34_03303	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B34_03304	COG1012	belongs to the aldehyde dehydrogenase family
B34_03305	COG2271	Major facilitator Superfamily
B34_03306	COG4948	Mandelate Racemase Muconate Lactonizing
B34_03307	COG2186	Transcriptional regulator
B34_03308	COG2721	sulfolactate sulfo-lyase activity
B34_03309	COG0745	RESPONSE REGULATOR receiver
B34_03310	COG2205	protein histidine kinase activity
B34_03311	COG1131	(ABC) transporter
B34_03316	COG3173	Aminoglycoside phosphotransferase
B34_03317	COG1846	Transcriptional regulator
B34_03318	COG0318	PFAM AMP-dependent synthetase and ligase
B34_03322	COG0789	Transcriptional regulator
B34_03327	COG0697	spore germination
B34_03328	COG1714	RDD family
B34_03329	COG1405	negative regulation of cell septum assembly
B34_03329	COG3012	SEC-C Motif Domain Protein
B34_03335	COG0583	DNA-binding transcription factor activity
B34_03336	COG1942	4-Oxalocrotonate Tautomerase
B34_03337	COG1028	Short-chain dehydrogenase reductase Sdr
B34_03340	COG1288	antiporter activity
B34_03342	COG0456	acetyltransferase
B34_03344	COG1164	Oligoendopeptidase f
B34_03345	COG2261	transglycosylase associated protein
B34_03347	COG0247	lactate metabolic process
B34_03348	COG0277	FAD linked oxidase domain protein
B34_03349	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B34_03350	COG1447	Phosphotransferase system cellobiose-specific component IIA
B34_03351	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B34_03352	COG1486	melibiose metabolic process
B34_03354	COG3394	polysaccharide catabolic process
B34_03358	COG3591	Belongs to the peptidase S1B family
B34_03359	COG1028	Short-chain dehydrogenase reductase Sdr
B34_03361	COG1595	DNA-templated transcription, initiation
B34_03363	COG3773	Cell wall hydrolase
B34_03364	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B34_03365	COG0791	NLP P60 protein
B34_03365	COG3883	PFAM NLP P60 protein
B34_03368	COG1131	(ABC) transporter
B34_03369	COG1309	transcriptional regulator
B34_03373	COG2310	stress, protein
B34_03374	COG2310	stress, protein
B34_03375	COG2310	stress, protein
B34_03376	COG0861	Integral membrane protein TerC family
B34_03380	COG3853	Toxic anion resistance protein (TelA)
B34_03381	COG0785	Cytochrome C biogenesis protein
B34_03383	COG0789	Transcriptional regulator
B34_03384	COG2223	nitrite transmembrane transporter activity
B34_03385	COG0039	L-malate dehydrogenase activity
B34_03386	COG1620	l-lactate permease
B34_03387	COG1280	lysine exporter protein (LysE YggA)
B34_03388	COG1113	amino acid transport
B34_03389	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
B34_03390	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B34_03391	COG3541	Predicted nucleotidyltransferase
B34_03392	COG0506	proline dehydrogenase activity
B34_03393	COG1012	belongs to the aldehyde dehydrogenase family
B34_03394	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B34_03395	COG2508	Transcriptional regulator
B34_03396	COG3689	TIGRFAM TIGR03943 family protein
B34_03397	COG0701	Predicted permease
B34_03398	COG3458	cephalosporin-C deacetylase activity
B34_03402	COG0765	amino acid transport
B34_03403	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B34_03404	COG2249	NAD(P)H dehydrogenase (quinone) activity
B34_03406	COG2723	6-phospho-beta-galactosidase activity
B34_03408	COG3209	COG3209 Rhs family protein
B34_03409	COG0515	serine threonine protein kinase
B34_03409	COG3266	domain, Protein
B34_03410	COG0840	transmembrane signaling receptor activity
B34_03410	COG3290	protein histidine kinase activity
B34_03411	COG3290	protein histidine kinase activity
B34_03411	COG0840	transmembrane signaling receptor activity
B34_03412	COG5444	nuclease activity
B34_03417	COG1176	ABC-type spermidine putrescine transport system, permease component I
B34_03418	COG1177	transmembrane transport
B34_03419	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B34_03420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B34_03421	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B34_03422	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
B34_03423	COG0697	spore germination
B34_03424	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B34_03426	COG2819	hydrolase of the alpha beta superfamily
B34_03428	COG2364	Membrane
B34_03430	COG1131	(ABC) transporter
B34_03435	COG1126	abc transporter atp-binding protein
B34_03436	COG0765	amino acid transport
B34_03437	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B34_03438	COG3829	transcription factor binding
B34_03439	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B34_03440	COG0833	amino acid
B34_03441	COG0010	Belongs to the arginase family
B34_03442	COG0583	DNA-binding transcription factor activity
B34_03443	COG0163	prenyltransferase activity
B34_03444	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
B34_03454	COG5444	nuclease activity
B34_03458	COG2972	Histidine kinase
B34_03459	COG4753	response regulator
B34_03459	COG2207	Transcriptional regulator
B34_03460	COG4213	ABC transporter substrate-binding protein
B34_03462	COG4214	carbohydrate transport
B34_03463	COG2271	Major facilitator Superfamily
B34_03464	COG1846	Transcriptional regulator
B34_03464	COG0456	acetyltransferase
B34_03465	COG1874	Beta-galactosidase
B34_03466	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
B34_03467	COG3104	oligopeptide transport
B34_03468	COG5434	Belongs to the glycosyl hydrolase 28 family
B34_03470	COG0697	spore germination
B34_03472	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B34_03473	COG0789	Transcriptional regulator
B34_03475	COG1136	(ABC) transporter
B34_03476	COG0577	efflux transmembrane transporter activity
B34_03477	COG0745	RESPONSE REGULATOR receiver
B34_03478	COG3850	Histidine kinase
B34_03478	COG5002	protein histidine kinase activity
B34_03479	COG0840	transmembrane signaling receptor activity
B34_03480	COG0527	aspartate kinase activity
B34_03481	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B34_03482	COG4605	iron ion homeostasis
B34_03483	COG4604	ABC transporter, ATP-binding protein
B34_03484	COG4607	ABC-type enterochelin transport system periplasmic component
B34_03485	COG2814	Major facilitator Superfamily
B34_03486	COG1309	transcriptional regulator
B34_03488	COG0778	Nitroreductase
B34_03489	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
B34_03490	COG0640	Transcriptional regulator
B34_03491	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B34_03492	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B34_03493	COG0531	amino acid
B34_03494	COG1012	belongs to the aldehyde dehydrogenase family
B34_03495	COG0697	spore germination
B34_03497	COG4549	nuclear export factor GLE1
B34_03498	COG1276	copper resistance
B34_03498	COG2372	response to copper ion
B34_03499	COG1349	DNA-binding transcription factor activity
B34_03500	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B34_03501	COG0243	molybdopterin cofactor binding
B34_03502	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B34_03503	COG2146	nitrite reductase [NAD(P)H] activity
B34_03504	COG1587	Uroporphyrinogen-III synthase
B34_03504	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B34_03505	COG1802	Transcriptional regulator
B34_03506	COG0471	metal ion transport
B34_03508	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B34_03511	COG3959	Transketolase, thiamine diphosphate binding domain
B34_03512	COG3958	Transketolase
B34_03513	COG0561	phosphatase activity
B34_03514	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
B34_03515	COG1914	H( )-stimulated, divalent metal cation uptake system
B34_03516	COG4336	lyase activity
B34_03517	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
B34_03518	COG1984	allophanate hydrolase subunit 2
B34_03519	COG1414	Transcriptional regulator
B34_03520	COG2755	lipolytic protein G-D-S-L family
B34_03521	COG2213	PTS system mannitol-specific
B34_03522	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
B34_03523	COG0246	Mannitol dehydrogenase
B34_03524	COG3711	transcriptional antiterminator
B34_03525	COG1028	Short-chain dehydrogenase reductase Sdr
B34_03526	COG1917	Cupin 2, conserved barrel domain protein
B34_03528	COG3871	stress protein (general stress protein 26)
B34_03530	COG1316	TRANSCRIPTIONal
B34_03531	COG2814	Major facilitator Superfamily
B34_03533	COG1522	sequence-specific DNA binding
B34_03534	COG0551	DNA topoisomerase type I activity
B34_03534	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B34_03535	COG0531	amino acid
B34_03536	COG0028	Belongs to the TPP enzyme family
B34_03537	COG3397	chitin binding
B34_03539	COG2801	Transposase and inactivated derivatives
B34_03541	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B34_03542	COG1914	H( )-stimulated, divalent metal cation uptake system
B34_03543	COG2261	transglycosylase associated protein
B34_03544	COG1027	Aspartate ammonia-lyase
B34_03545	COG1819	glycosyl
B34_03546	COG4876	unkown
B34_03547	COG2217	Heavy metal translocating P-type atpase
B34_03549	COG0662	Cupin 2, conserved barrel domain protein
B34_03550	COG3729	General stress protein
B34_03551	COG0628	permease
B34_03552	COG1301	dicarboxylic acid transport
B34_03553	COG1131	(ABC) transporter
B34_03554	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
B34_03556	COG1960	acyl-CoA dehydrogenase activity
B34_03559	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B34_03560	COG1181	Belongs to the D-alanine--D-alanine ligase family
B34_03561	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B34_03563	COG0513	Belongs to the DEAD box helicase family
B34_03564	COG3402	PFAM membrane-flanked domain
B34_03565	COG3428	Bacterial PH domain
B34_03566	COG0705	Rhomboid family
B34_03567	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
B34_03568	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B34_03569	COG0864	Transcriptional regulator
B34_03570	COG2337	Toxic component of a toxin-antitoxin (TA) module
B34_03571	COG1366	Belongs to the anti-sigma-factor antagonist family
B34_03572	COG1366	Belongs to the anti-sigma-factor antagonist family
B34_03573	COG2172	sigma factor antagonist activity
B34_03574	COG2208	phosphoserine phosphatase activity
B34_03576	COG2172	sigma factor antagonist activity
B34_03577	COG1191	sigma factor activity
B34_03578	COG2208	phosphoserine phosphatase activity
B34_03579	COG2183	response to ionizing radiation
B34_03580	COG1309	transcriptional regulator
B34_03581	COG1033	growth of symbiont in host cell
B34_03581	COG2409	Drug exporters of the RND superfamily
B34_03582	COG3091	SprT-like family
B34_03590	COG0582	viral genome integration into host DNA
B34_03591	COG2856	Zn peptidase
B34_03592	COG1396	sequence-specific DNA binding
B34_03596	COG1674	ftsk spoiiie
B34_03597	COG2946	Replication initiation factor
B34_03605	COG0433	COG0433 Predicted ATPase
B34_03607	COG5644	endopeptidase inhibitor activity
B34_03608	COG0791	NLP P60 protein
B34_03608	COG0741	lytic transglycosylase activity
B34_03612	COG0457	Tetratricopeptide repeat
B34_03616	COG1476	TRANSCRIPTIONal
B34_03617	COG3239	Fatty acid desaturase
B34_03618	COG1278	Cold shock
B34_03621	COG2364	Membrane
B34_03622	COG1846	Transcriptional regulator
B34_03623	COG0456	acetyltransferase
B34_03624	COG2808	Putative FMN-binding domain
B34_03626	COG1733	regulation of RNA biosynthetic process
B34_03627	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B34_03629	COG0583	DNA-binding transcription factor activity
B34_03632	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
B34_03633	COG1113	amino acid transport
B34_03636	COG1595	DNA-templated transcription, initiation
B34_03638	COG2755	lipolytic protein G-D-S-L family
B34_03638	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
B34_03639	COG2814	Major facilitator Superfamily
B34_03640	COG0745	RESPONSE REGULATOR receiver
B34_03640	COG2972	Histidine kinase
B34_03641	COG3279	Response regulator of the LytR AlgR family
B34_03643	COG3764	Sortase (surface protein transpeptidase)
B34_03644	COG2814	Major facilitator Superfamily
B34_03652	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
B34_03653	COG0802	atpase or kinase
B34_03654	COG1214	PFAM Peptidase M22, glycoprotease
B34_03655	COG0456	acetyltransferase
B34_03656	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
B34_03657	COG0488	(ABC) transporter
B34_03658	COG0315	cyclic pyranopterin monophosphate synthase activity
B34_03659	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
B34_03660	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B34_03661	COG0805	protein transport
B34_03663	COG1266	CAAX protease self-immunity
B34_03664	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
B34_03665	COG0459	protein refolding
B34_03671	COG2720	vancomycin resistance protein
B34_03674	COG2135	peptidase activity
B34_03675	COG1309	transcriptional regulator
B34_03676	COG3848	Pyruvate phosphate dikinase
B34_03676	COG0574	Belongs to the PEP-utilizing enzyme family
B34_03678	COG3189	MarR family transcriptional regulator
B34_03679	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
B34_03680	COG2272	Belongs to the type-B carboxylesterase lipase family
B34_03681	COG2814	Major facilitator Superfamily
B34_03682	COG1842	Phage shock protein A
B34_03683	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B34_03684	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
B34_03685	COG4260	virion core protein, lumpy skin disease virus
B34_03687	COG1378	Sugar-specific transcriptional regulator TrmB
B34_03688	COG1280	lysine exporter protein (LysE YggA)
B34_03689	COG3339	Conserved Protein
B34_03690	COG0772	Belongs to the SEDS family
B34_03691	COG0772	Belongs to the SEDS family
B34_03695	COG0726	polysaccharide deacetylase
B34_03698	COG1609	Transcriptional regulator
B34_03699	COG0366	Alpha amylase catalytic
B34_03700	COG2182	Extracellular solute-binding protein
B34_03701	COG1175	transmembrane transport
B34_03702	COG3833	ABC-type maltose transport systems, permease component
B34_03703	COG5521	maltodextrose utilization protein MalA
B34_03704	COG1554	hydrolase, family 65, central catalytic
B34_03705	COG0366	Alpha amylase catalytic
B34_03706	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B34_03707	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B34_03708	COG1846	Transcriptional regulator
B34_03711	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
B34_03712	COG0823	Involved in the tonB-independent uptake of proteins
B34_03718	COG0702	epimerase
B34_03720	COG2132	Multicopper oxidase
B34_03723	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
B34_03724	COG0714	Associated with various cellular activities
B34_03725	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
B34_03726	COG1305	Transglutaminase-like
B34_03727	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B34_03727	COG0519	Catalyzes the synthesis of GMP from XMP
B34_03728	COG2252	PERMEase
B34_03731	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
B34_03733	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
B34_03734	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B34_03735	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B34_03736	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
B34_03737	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B34_03738	COG0047	phosphoribosylformylglycinamidine synthase activity
B34_03739	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B34_03740	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
B34_03741	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
B34_03742	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B34_03743	COG0138	bifunctional purine biosynthesis protein purh
B34_03744	COG0151	Belongs to the GarS family
B34_03746	COG2124	cytochrome p450
B34_03751	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
B34_03752	COG1470	cell adhesion involved in biofilm formation
B34_03753	COG4496	protein, YerC YecD
B34_03754	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
B34_03755	COG0210	DNA helicase
B34_03756	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B34_03757	COG4851	CamS sex pheromone cAM373 precursor
B34_03758	COG2188	Transcriptional regulator
B34_03762	COG1735	metal-dependent hydrolase with the TIM-barrel fold
B34_03763	COG0626	cystathionine gamma-synthase activity
B34_03764	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
B34_03765	COG3457	Alanine racemase
B34_03766	COG0363	glucosamine-6-phosphate deaminase activity
B34_03767	COG1285	pathogenesis
B34_03768	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B34_03770	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B34_03771	COG0154	amidase activity
B34_03772	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B34_03775	COG4124	Belongs to the glycosyl hydrolase 26 family
B34_03776	COG1309	transcriptional regulator
B34_03777	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B34_03779	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B34_03780	COG1957	nucleoside hydrolase
B34_03781	COG1597	lipid kinase activity
B34_03782	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B34_03784	COG2190	(PTS) system
B34_03784	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B34_03784	COG1263	PTS System
B34_03785	COG2723	6-phospho-beta-galactosidase activity
B34_03786	COG3711	transcriptional antiterminator
B34_03787	COG0457	Tetratricopeptide repeat
B34_03791	COG0217	transcriptional regulatory protein
B34_03794	COG1012	belongs to the aldehyde dehydrogenase family
B34_03795	COG0840	transmembrane signaling receptor activity
B34_03796	COG0471	metal ion transport
B34_03797	COG0488	(ABC) transporter
B34_03799	COG1469	GTP cyclohydrolase I activity
B34_03803	COG0523	cobalamin synthesis protein
B34_03804	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
B34_03805	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B34_03806	COG0156	8-amino-7-oxononanoate synthase activity
B34_03807	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
B34_03808	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
B34_03809	COG2124	cytochrome p450
B34_03811	COG0789	Transcriptional regulator
B34_03812	COG2814	Major facilitator Superfamily
B34_03813	COG0488	(ABC) transporter
B34_03814	COG0513	Belongs to the DEAD box helicase family
B34_03815	COG2130	NADP-dependent
B34_03817	COG0471	metal ion transport
B34_03820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B34_03822	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
B34_03823	COG5658	integral membrane protein
B34_03824	COG0640	Transcriptional regulator
B34_03825	COG1254	Belongs to the acylphosphatase family
B34_03826	COG2258	MOSC domain
B34_03829	COG0024	Methionine aminopeptidase
B34_03830	COG1368	sulfuric ester hydrolase activity
B34_03832	COG1115	amino acid carrier protein
B34_03833	COG1263	PTS System
B34_03833	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B34_03834	COG0366	Alpha amylase catalytic
B34_03835	COG2188	Transcriptional regulator
B34_03840	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B34_03841	COG1045	serine acetyltransferase
B34_03842	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B34_03844	COG1215	transferase activity, transferring glycosyl groups
B34_03845	COG0463	Glycosyl transferase, family 2
B34_03845	COG0457	Tetratricopeptide repeat
B34_03847	COG0673	inositol 2-dehydrogenase activity
B34_03850	COG1733	regulation of RNA biosynthetic process
B34_03851	COG0778	Nitroreductase
B34_03852	COG0737	Belongs to the 5'-nucleotidase family
B34_03853	COG0693	protein deglycase activity
B34_03854	COG4840	Belongs to the UPF0435 family
B34_03855	COG1115	amino acid carrier protein
B34_03856	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B34_03857	COG4980	gas vesicle protein
B34_03858	COG1295	ribonuclease BN
B34_03860	COG0477	Major facilitator Superfamily
B34_03862	COG0387	Pfam Sodium calcium exchanger
B34_03864	COG0535	radical SAM domain protein
B34_03866	COG0726	polysaccharide deacetylase
B34_03867	COG0371	Dehydrogenase
B34_03869	COG0598	Magnesium transport protein CorA
B34_03870	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
B34_03871	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B34_03872	COG4637	Psort location Cytoplasmic, score
B34_03876	COG1819	glycosyl
B34_03879	COG0477	Major facilitator Superfamily
B34_03880	COG1263	PTS System
B34_03880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B34_03881	COG3711	transcriptional antiterminator
B34_03883	COG0288	reversible hydration of carbon dioxide
B34_03884	COG3002	Belongs to the UPF0753 family
B34_03885	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B34_03886	COG5609	conserved protein (DUF2294)
B34_03888	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B34_03889	COG0022	dehydrogenase e1 component
B34_03890	COG0508	dehydrogenase complex catalyzes the overall conversion of
B34_03891	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B34_03892	COG3284	Transcriptional regulator
B34_03893	COG1742	UPF0060 membrane protein
B34_03894	COG1486	melibiose metabolic process
B34_03895	COG1737	Transcriptional regulator
B34_03896	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B34_03896	COG1263	PTS System
B34_03899	COG1733	regulation of RNA biosynthetic process
B34_03900	COG2259	Doxx family
B34_03901	COG2514	catechol 2,3-dioxygenase activity
B34_03903	COG3507	Belongs to the glycosyl hydrolase 43 family
B34_03904	COG1917	Cupin 2, conserved barrel domain protein
B34_03904	COG2207	Transcriptional regulator
B34_03905	COG1653	transport
B34_03906	COG1653	transport
B34_03907	COG2249	NAD(P)H dehydrogenase (quinone) activity
B34_03908	COG1051	belongs to the nudix hydrolase family
B34_03910	COG0392	lysyltransferase activity
B34_03910	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
B34_03912	COG0384	phenazine biosynthesis protein PhzF
B34_03913	COG0778	Nitroreductase
B34_03917	COG1090	epimerase
B34_03918	COG2137	regulation of response to DNA damage stimulus
B34_03923	COG0463	Glycosyl transferase, family 2
B34_03925	COG4485	Bacterial membrane protein, YfhO
B34_03926	COG1988	membrane-bound metal-dependent
B34_03927	COG1194	a g-specific adenine glycosylase
B34_03929	COG1028	Short-chain dehydrogenase reductase Sdr
B34_03932	COG3557	Belongs to the UPF0374 family
B34_03933	COG1132	(ABC) transporter
B34_03934	COG0444	Belongs to the ABC transporter superfamily
B34_03935	COG4608	Belongs to the ABC transporter superfamily
B34_03936	COG0747	negative chemotaxis
B34_03939	COG4129	membrane
B34_03940	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B34_03941	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B34_03942	COG0735	belongs to the Fur family
B34_03990	COG0582	viral genome integration into host DNA
B34_03997	COG1802	Transcriptional regulator
B34_03997	COG4626	Terminase
B34_04010	COG3953	SLT domain
B34_04010	COG5280	Phage tail tape measure protein TP901
B34_04012	COG1705	Flagellar rod assembly protein muramidase FlgJ
B34_04013	COG5434	Belongs to the glycosyl hydrolase 28 family
B34_04021	COG5444	nuclease activity
B34_04022	COG0457	Tetratricopeptide repeat
B34_04026	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B34_04028	COG0457	Tetratricopeptide repeat
B34_04034	COG5444	nuclease activity
B34_04035	COG0457	Tetratricopeptide repeat
B34_04036	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B34_04037	COG0710	3-dehydroquinate dehydratase activity
B34_04038	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
B34_04039	COG1116	anion transmembrane transporter activity
B34_04040	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B34_04041	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B34_04042	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B34_04044	COG1476	TRANSCRIPTIONal
B34_04046	COG1131	(ABC) transporter
B34_04050	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B34_04052	COG3382	B3 4 domain protein
B34_04053	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
B34_04055	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
B34_04056	COG0789	Transcriptional regulator
B34_04057	COG1664	Polymer-forming cytoskeletal
B34_04059	COG2766	serine protein kinase
B34_04060	COG2718	Belongs to the UPF0229 family
B34_04061	COG1566	PFAM secretion protein HlyD family protein
B34_04062	COG2814	Major facilitator Superfamily
B34_04063	COG0655	NAD(P)H dehydrogenase (quinone) activity
B34_04065	COG1131	(ABC) transporter
B34_04066	COG1131	(ABC) transporter
B34_04067	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
B34_04068	COG2801	Transposase and inactivated derivatives
B34_04070	COG1278	Cold shock
B34_04071	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B34_04072	COG2011	ABC-type metal ion transport system permease component
B34_04073	COG1464	Belongs to the NlpA lipoprotein family
B34_04074	COG1823	symporter activity
B34_04079	COG5577	PFAM Coat F domain
B34_04080	COG5002	protein histidine kinase activity
B34_04081	COG4085	toxin activity
B34_04081	COG1525	nuclease
B34_04081	COG0737	Belongs to the 5'-nucleotidase family
B34_04082	COG3764	Sortase (surface protein transpeptidase)
B34_04083	COG0564	pseudouridine synthase activity
B34_04085	COG0517	IMP dehydrogenase activity
B34_04086	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B34_04087	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B34_04087	COG3153	acetyltransferase
B34_04089	COG0488	(ABC) transporter
B34_04090	COG2116	formate transmembrane transporter activity
B34_04091	COG0679	Auxin Efflux Carrier
B34_04092	COG0604	alcohol dehydrogenase
B34_04093	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
B34_04094	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B34_04095	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B34_04097	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B34_04098	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B34_04101	COG2203	Gaf domain
B34_04101	COG4585	Histidine kinase
B34_04102	COG2197	response regulator
B34_04103	COG0431	NADPH-dependent FMN reductase
B34_04106	COG1959	2 iron, 2 sulfur cluster binding
B34_04107	COG1017	nitric oxide dioxygenase activity
B34_04107	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B34_04108	COG2719	SpoVR family
B34_04109	COG1388	LysM domain
B34_04109	COG0791	NLP P60 protein
B34_04110	COG0583	DNA-binding transcription factor activity
B34_04111	COG0372	Belongs to the citrate synthase family
B34_04112	COG2133	pyrroloquinoline quinone binding
B34_04113	COG1028	Short-chain dehydrogenase reductase Sdr
B34_04114	COG0733	neurotransmitter:sodium symporter activity
B34_04116	COG2207	Transcriptional regulator
B34_04116	COG3708	Transcriptional regulator
B34_04117	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B34_04121	COG1595	DNA-templated transcription, initiation
B34_04122	COG0662	Cupin 2, conserved barrel domain protein
B34_04124	COG0204	Acyl-transferase
B34_04126	COG3152	Membrane
B34_04128	COG1309	transcriptional regulator
B34_04129	COG1253	flavin adenine dinucleotide binding
B34_04130	COG0789	Transcriptional regulator
B34_04132	COG1253	flavin adenine dinucleotide binding
B34_04136	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B34_04137	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B34_04138	COG0584	glycerophosphoryl diester phosphodiesterase
B34_04140	COG0668	transmembrane transport
B34_04141	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B34_04144	COG0726	polysaccharide deacetylase
B34_04146	COG1757	Na H antiporter
B34_04147	COG2017	converts alpha-aldose to the beta-anomer
B34_04151	COG0589	response to stress
B34_04152	COG1132	(ABC) transporter
B34_04153	COG1132	(ABC) transporter
B34_04154	COG0702	epimerase
B34_04158	COG3842	ATPase activity
B34_04159	COG2508	Transcriptional regulator
B34_04161	COG0189	ligase activity
B34_04162	COG0189	ligase activity
B34_04163	COG4399	Belongs to the UPF0754 family
B34_04164	COG3679	Belongs to the UPF0342 family
B34_04165	COG0561	phosphatase activity
B34_04166	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B34_04167	COG0475	glutathione-regulated potassium exporter activity
B34_04168	COG0490	domain, Protein
B34_04170	COG1024	Enoyl-CoA hydratase
B34_04171	COG0457	Tetratricopeptide repeat
B34_04175	COG4152	abc transporter atp-binding protein
B34_04176	COG1668	transmembrane transport
B34_04177	COG0420	3'-5' exonuclease activity
B34_04178	COG4717	serine-type aminopeptidase activity
B34_04179	COG3481	metal-dependent phosphohydrolase, HD sub domain
B34_04181	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B34_04185	COG1846	Transcriptional regulator
B34_04186	COG4980	gas vesicle protein
B34_04189	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
B34_04190	COG0537	adenosine 5'-monophosphoramidase activity
B34_04191	COG1131	(ABC) transporter
B34_04192	COG4473	ABC transporter
B34_04194	COG1473	amidohydrolase
B34_04195	COG3069	C4-dicarboxylate transmembrane transporter activity
B34_04196	COG2329	Antibiotic biosynthesis monooxygenase
B34_04197	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B34_04198	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
B34_04201	COG1309	transcriptional regulator
B34_04202	COG1511	domain protein
B34_04203	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B34_04204	COG1363	Peptidase, m42
B34_04206	COG1301	dicarboxylic acid transport
B34_04208	COG1234	tRNA 3'-trailer cleavage
B34_04209	COG0095	Lipoate-protein ligase
B34_04210	COG0318	PFAM AMP-dependent synthetase and ligase
B34_04212	COG1396	sequence-specific DNA binding
B34_04215	COG0501	Belongs to the peptidase M48B family
B34_04217	COG0697	spore germination
B34_04218	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
B34_04219	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B34_04220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B34_04221	COG0406	alpha-ribazole phosphatase activity
B34_04222	COG0840	transmembrane signaling receptor activity
B34_04223	COG0723	plastoquinol--plastocyanin reductase activity
B34_04223	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B34_04224	COG1028	Short-chain dehydrogenase reductase Sdr
B34_04226	COG4903	ComK protein
B34_04228	COG0398	Pfam SNARE associated Golgi protein
B34_04229	COG0681	Belongs to the peptidase S26 family
B34_04230	COG1404	Belongs to the peptidase S8 family
B34_04232	COG2508	Transcriptional regulator
B34_04234	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B34_04235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B34_04236	COG3257	ureidoglycine aminohydrolase activity
B34_04237	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
B34_04238	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
B34_04239	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
B34_04240	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B34_04241	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B34_04243	COG0549	Belongs to the carbamate kinase family
B34_04244	COG2814	Major facilitator Superfamily
B34_04246	COG0457	Tetratricopeptide repeat
B34_04254	COG1486	melibiose metabolic process
B34_04255	COG3180	Ammonia monooxygenase
B34_04258	COG3546	catalase activity
B34_04259	COG0318	PFAM AMP-dependent synthetase and ligase
B34_04260	COG0477	Major facilitator Superfamily
B34_04260	COG2814	Major facilitator Superfamily
B34_04262	COG5002	protein histidine kinase activity
B34_04263	COG0745	RESPONSE REGULATOR receiver
B34_04264	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
B34_04265	COG0725	ABC transporter, periplasmic molybdate-binding protein
B34_04266	COG4149	molybdate abc transporter
B34_04267	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
B34_04268	COG1074	ATP-dependent DNA helicase activity
B34_04269	COG0420	3'-5' exonuclease activity
B34_04270	COG0419	ATPase involved in DNA repair
B34_04279	COG5337	Spore coat protein CotH
B34_04281	COG0179	Fumarylacetoacetate (FAA) hydrolase
B34_04286	COG0367	asparagine synthase
B34_04287	COG0004	ammonium transporteR
B34_04288	COG0004	ammonium transporteR
B34_04289	COG0347	Belongs to the P(II) protein family
B34_04290	COG0534	Mate efflux family protein
B34_04291	COG2207	Transcriptional regulator
B34_04291	COG1917	Cupin 2, conserved barrel domain protein
B34_04293	COG1609	Transcriptional regulator
B34_04294	COG0673	inositol 2-dehydrogenase activity
B34_04295	COG0673	inositol 2-dehydrogenase activity
B34_04300	COG1279	arginine transmembrane transporter activity
B34_04301	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B34_04303	COG0076	glutamate decarboxylase activity
B34_04308	COG2153	protein acetylation
B34_04309	COG1028	Short-chain dehydrogenase reductase Sdr
B34_04310	COG2378	regulation of single-species biofilm formation
B34_04311	COG0646	methionine synthase
B34_04311	COG1410	methionine synthase
B34_04312	COG0646	methionine synthase
B34_04312	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
B34_04313	COG1666	GTP binding
B34_04314	COG2996	Protein conserved in bacteria
B34_04317	COG1307	EDD domain protein, DegV family
B34_04318	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B34_04320	COG0516	GMP reductase activity
B34_04322	COG0561	phosphatase activity
B34_04323	COG1073	alpha beta
B34_04324	COG2151	metal-sulfur cluster biosynthetic enzyme
B34_04325	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
B34_04326	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
B34_04327	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B34_04328	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B34_04329	COG0505	Belongs to the CarA family
B34_04330	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B34_04331	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B34_04332	COG1968	undecaprenyl-diphosphatase activity
B34_04335	COG2267	carboxylic ester hydrolase activity
B34_04337	COG1744	ABC transporter substrate-binding protein PnrA-like
B34_04340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B34_04341	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B34_04342	COG5504	Zn-dependent protease
B34_04343	COG0444	Belongs to the ABC transporter superfamily
B34_04344	COG4608	Belongs to the ABC transporter superfamily
B34_04346	COG0601	transmembrane transport
B34_04347	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B34_04352	COG0180	Tryptophanyl-tRNA synthetase
B34_04353	COG4166	transmembrane transport
B34_04354	COG0601	transmembrane transport
B34_04355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B34_04356	COG0444	Belongs to the ABC transporter superfamily
B34_04357	COG4608	Belongs to the ABC transporter superfamily
B34_04358	COG0456	acetyltransferase
B34_04359	COG1393	Belongs to the ArsC family
B34_04360	COG0861	Integral membrane protein TerC family
B34_04361	COG4862	establishment of competence for transformation
B34_04365	COG4565	transcriptional regulatory protein
B34_04366	COG3290	protein histidine kinase activity
B34_04367	COG4469	Competence protein
B34_04368	COG1164	Oligoendopeptidase f
B34_04371	COG2346	COG2346, Truncated hemoglobins
B34_04372	COG0741	lytic transglycosylase activity
B34_04373	COG4116	CYTH
B34_04375	COG2357	RelA SpoT domain protein
B34_04376	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B34_04377	COG0564	pseudouridine synthase activity
B34_04378	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B34_04379	COG0475	glutathione-regulated potassium exporter activity
B34_04379	COG0569	domain protein
B34_04380	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
B34_04381	COG0352	thiamine-phosphate diphosphorylase activity
B34_04383	COG2104	thiamine diphosphate biosynthetic process
B34_04384	COG2022	thiamine diphosphate biosynthetic process
B34_04385	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B34_04386	COG0351	phosphomethylpyrimidine kinase
B34_04387	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B34_04398	COG0210	DNA helicase
B34_04400	COG0586	Pfam SNARE associated Golgi protein
B34_04401	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B34_04402	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B34_04403	COG2246	polysaccharide biosynthetic process
B34_04404	COG2153	protein acetylation
B34_04405	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
B34_04406	COG2382	esterase
B34_04409	COG0626	cystathionine gamma-synthase activity
B34_04410	COG0626	cystathionine gamma-synthase activity
B34_04411	COG5505	Protein of unknown function (DUF819)
B34_04414	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B34_04415	COG3507	Belongs to the glycosyl hydrolase 43 family
B34_04418	COG0110	maltose O-acetyltransferase activity
B34_04420	COG0583	DNA-binding transcription factor activity
B34_04421	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B34_04422	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B34_04423	COG0583	DNA-binding transcription factor activity
B34_04424	COG0697	spore germination
B34_04425	COG0346	lactoylglutathione lyase activity
B34_04427	COG1388	LysM domain
B34_04427	COG3584	3D domain protein
B34_04428	COG2814	Major facilitator Superfamily
B34_04429	COG1309	transcriptional regulator
B34_04432	COG5444	nuclease activity
B34_04433	COG5444	nuclease activity
B34_04434	COG4195	phage-related replication protein
B34_04435	COG2856	Zn peptidase
B34_04436	COG1396	sequence-specific DNA binding
B34_04439	COG1522	sequence-specific DNA binding
B34_04440	COG1484	DNA-dependent DNA replication
B34_04444	COG1595	DNA-templated transcription, initiation
B34_04445	COG3728	DNA packaging
B34_04445	COG5484	DNA packaging
B34_04446	COG1783	phage Terminase large subunit
B34_04447	COG5518	Phage portal protein
B34_04448	COG5518	Phage portal protein
B34_04449	COG0338	D12 class N6 adenine-specific DNA methyltransferase
B34_04450	COG4653	Phage capsid family
B34_04459	COG5412	phage tail tape measure protein
B34_04459	COG3953	SLT domain
B34_04460	COG1652	LysM domain
B34_04461	COG4193	domain, Protein
B34_04463	COG3628	GPW Gp25 family protein
B34_04464	COG3299	homolog of phage Mu protein gp47
B34_04465	COG3778	Protein conserved in bacteria
B34_04472	COG1802	Transcriptional regulator
B34_04473	COG1063	alcohol dehydrogenase
B34_04474	COG1312	Catalyzes the dehydration of D-mannonate
B34_04475	COG1028	Short-chain dehydrogenase reductase Sdr
B34_04476	COG1063	alcohol dehydrogenase
B34_04477	COG2271	Major facilitator Superfamily
B34_04480	COG0306	phosphate transporter
B34_04481	COG1392	Phosphate transport regulator
B34_04482	COG0405	Gamma-glutamyltransferase
B34_04483	COG5578	integral membrane protein
B34_04484	COG5578	integral membrane protein
B34_04485	COG2972	Histidine kinase
B34_04486	COG4753	response regulator
B34_04486	COG2207	Transcriptional regulator
B34_04487	COG1653	transport
B34_04488	COG1175	transmembrane transport
B34_04489	COG0395	ABC-type sugar transport system, permease component
B34_04490	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
B34_04491	COG2207	Transcriptional regulator
B34_04492	COG2755	lipolytic protein G-D-S-L family
B34_04494	COG5578	integral membrane protein
B34_04495	COG3401	FG-GAP repeat protein
B34_04497	COG2755	lipolytic protein G-D-S-L family
B34_04498	COG3401	FG-GAP repeat protein
B34_04499	COG0667	Aldo Keto reductase
B34_04500	COG2755	lipolytic protein G-D-S-L family
B34_04501	COG1874	Beta-galactosidase
B34_04503	COG1653	transport
B34_04504	COG4209	transmembrane transport
B34_04505	COG0395	ABC-type sugar transport system, permease component
B34_04506	COG0531	amino acid
B34_04507	COG0346	lactoylglutathione lyase activity
B34_04509	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B34_04510	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B34_04511	COG2362	D-Aminopeptidase
B34_04512	COG0601	transmembrane transport
B34_04513	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B34_04514	COG0444	Belongs to the ABC transporter superfamily
B34_04515	COG4166	transmembrane transport
B34_04516	COG1619	proteins homologs of microcin C7 resistance protein MccF
B34_04517	COG4948	Mandelate Racemase Muconate Lactonizing
B34_04518	COG0791	NLP P60 protein
B34_04519	COG4608	Belongs to the ABC transporter superfamily
B34_04520	COG1834	amidinotransferase
B34_04521	COG1607	acyl-coa hydrolase
B34_04522	COG2323	membrane
B34_04523	COG3866	Pectate lyase
B34_04528	COG2318	DinB family
B34_04529	COG2076	Multidrug Resistance protein
B34_04530	COG2076	Multidrug Resistance protein
B34_04531	COG0788	formyltetrahydrofolate deformylase activity
B34_04532	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
B34_04533	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
B34_04534	COG1764	response to oxidative stress
B34_04535	COG1846	Transcriptional regulator
B34_04536	COG1764	response to oxidative stress
B34_04538	COG0590	tRNA wobble adenosine to inosine editing
B34_04539	COG0406	alpha-ribazole phosphatase activity
B34_04542	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B34_04543	COG1404	Belongs to the peptidase S8 family
B34_04545	COG2239	Acts as a magnesium transporter
B34_04547	COG0789	Transcriptional regulator
B34_04551	COG1846	Transcriptional regulator
B34_04552	COG3285	dna ligase
B34_04552	COG1793	dna ligase
B34_04553	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
B34_04554	COG3300	MHYT domain
B34_04554	COG5001	Diguanylate cyclase
B34_04555	COG0586	Pfam SNARE associated Golgi protein
B34_04556	COG0861	Integral membrane protein TerC family
B34_04557	COG1191	sigma factor activity
B34_04561	COG0501	Belongs to the peptidase M48B family
B34_04562	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B34_04563	COG0768	penicillin binding
B34_04566	COG3594	Acyltransferase
B34_04567	COG5002	protein histidine kinase activity
B34_04568	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B34_04570	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
B34_04571	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
B34_04572	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B34_04573	COG0436	Aminotransferase
B34_04574	COG1850	ribulose-bisphosphate carboxylase activity
B34_04575	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
B34_04575	COG0235	Class ii aldolase
B34_04576	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
B34_04577	COG0346	lactoylglutathione lyase activity
B34_04578	COG3339	Conserved Protein
B34_04580	COG3852	Histidine kinase
B34_04581	COG1846	Transcriptional regulator
B34_04582	COG1360	Flagellar Motor Protein
B34_04583	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
B34_04584	COG0542	response to heat
B34_04585	COG3949	Membrane
B34_04586	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
B34_04587	COG0720	synthase
B34_04588	COG0602	queuosine metabolic process
B34_04589	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B34_04590	COG4974	Belongs to the 'phage' integrase family
B34_04591	COG4974	Belongs to the 'phage' integrase family
B34_04596	COG1793	dna ligase
B34_04601	COG5444	nuclease activity
B34_04619	COG0582	viral genome integration into host DNA
B34_04644	COG3409	Peptidoglycan-binding domain 1 protein
B34_04644	COG1388	LysM domain
B34_04644	COG5632	N-Acetylmuramoyl-L-alanine amidase
B34_04650	COG0582	viral genome integration into host DNA
B34_04651	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B34_04654	COG0457	Tetratricopeptide repeat
B34_04655	COG0457	Tetratricopeptide repeat
B34_04656	COG3739	integral membrane protein
B34_04657	COG3655	Transcriptional regulator
B34_04664	COG4873	Protein conserved in bacteria
B34_04666	COG3773	Cell wall hydrolase
B34_04667	COG2244	polysaccharide biosynthetic process
B34_04668	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B34_04669	COG2217	Heavy metal translocating P-type atpase
B34_04670	COG0006	proline dipeptidase activity
B34_04673	COG1609	Transcriptional regulator
B34_04674	COG3711	transcriptional antiterminator
B34_04675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B34_04675	COG2190	(PTS) system
B34_04675	COG1263	PTS System
B34_04676	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B34_04677	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B34_04679	COG1533	DNA photolyase activity
B34_04680	COG0456	acetyltransferase
B34_04681	COG0840	transmembrane signaling receptor activity
B34_04682	COG1028	Short-chain dehydrogenase reductase Sdr
B34_04683	COG2084	Dehydrogenase
B34_04684	COG2340	Cysteine-rich secretory protein family
B34_04685	COG0768	penicillin binding
B34_04686	COG4191	Histidine kinase
B34_04687	COG0436	Aminotransferase
B34_04689	COG1714	RDD family
B34_04691	COG0835	chemotaxis
B34_04691	COG0784	Response regulator, receiver
B34_04693	COG2814	Major facilitator Superfamily
B34_04694	COG1376	ErfK ybiS ycfS ynhG family protein
B34_04695	COG1408	metallophosphoesterase
B34_04696	COG1028	Short-chain dehydrogenase reductase Sdr
B34_04697	COG2200	EAL domain
B34_04699	COG4703	Protein of unknown function (DUF1797)
B34_04701	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
B34_04703	COG0517	IMP dehydrogenase activity
B34_04704	COG0583	DNA-binding transcription factor activity
B34_04705	COG0716	FMN binding
B34_04707	COG0716	FMN binding
B34_04708	COG2171	N-acyltransferase activity
B34_04709	COG1473	amidohydrolase
B34_04711	COG0450	alkyl hydroperoxide reductase
B34_04712	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B34_04715	COG0746	molybdenum cofactor guanylyltransferase activity
B34_04716	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B34_04717	COG0303	'Molybdopterin
B34_04718	COG1763	Mo-molybdopterin cofactor biosynthetic process
B34_04719	COG0314	molybdopterin synthase activity
B34_04720	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
B34_04722	COG1132	(ABC) transporter
B34_04723	COG1132	(ABC) transporter
B34_04725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B34_04726	COG1136	(ABC) transporter
B34_04727	COG0577	efflux transmembrane transporter activity
B34_04728	COG1349	DNA-binding transcription factor activity
B34_04729	COG1105	Belongs to the carbohydrate kinase PfkB family
B34_04730	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B34_04730	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B34_04730	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B34_04734	COG0488	(ABC) transporter
B34_04736	COG2309	aminopeptidase activity