locus-tag class description BaDB11_00001 ENOG4106F1P AAA ATPase, central domain protein BaDB11_00005 ENOG4107EV6 Inherit from COG: YD repeat protein BaDB11_00006 ENOG4106ANW SMI1_KNR4 BaDB11_00007 ENOG4106ANW SMI1_KNR4 BaDB11_00016 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BaDB11_00022 ENOG4105E4C Lytic transglycosylase catalytic BaDB11_00023 ENOG4105E4C Lytic transglycosylase catalytic BaDB11_00024 ENOG4105D7V transposase BaDB11_00044 ENOG41068G1 BaDB11_00074 ENOG4108NE4 BaDB11_00086 ENOG4107NTZ BaDB11_00095 ENOG4106J6E BaDB11_00101 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin BaDB11_00104 ENOG4107D0N BaDB11_00114 ENOG4107QYX exodeoxyribonuclease v alpha BaDB11_00116 ENOG4105GJD protein, conserved in bacteria BaDB11_00123 ENOG4108J9Q DNA ligase BaDB11_00136 ENOG4106YR8 BaDB11_00137 ENOG41088HM BaDB11_00139 ENOG4106PTB DnaB-like helicase C terminal domain BaDB11_00140 ENOG4106IVX BaDB11_00142 ENOG4106J9J DNA polymerase BaDB11_00144 ENOG4106J9J DNA polymerase BaDB11_00162 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BaDB11_00163 ENOG4107S45 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BaDB11_00164 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BaDB11_00165 ENOG4106ITI Glutaredoxin BaDB11_00168 ENOG4107YUK This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) BaDB11_00171 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) BaDB11_00187 ENOG4108UV1 cellular component movement BaDB11_00189 ENOG4106Y37 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity) BaDB11_00192 ENOG4106F1P AAA ATPase, central domain protein BaDB11_00193 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BaDB11_00194 ENOG4105CXI aluminum resistance protein BaDB11_00195 ENOG4105KV4 Transcriptional regulator BaDB11_00196 ENOG4105C5F glutamine synthetase BaDB11_00216 ENOG4108MK9 spermidine N(1)-acetyltransferase BaDB11_00219 ENOG4108IFH alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BaDB11_00224 ENOG41062JF Transcriptional regulator BaDB11_00225 ENOG41090MY MarR family Transcriptional regulator BaDB11_00226 ENOG4108TVJ Nitroreductase BaDB11_00227 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BaDB11_00228 ENOG4107XWI flavin reductase domain protein, FMN-binding BaDB11_00229 ENOG4105CS1 NAD(P)H quinone oxidoreductase BaDB11_00232 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) BaDB11_00233 ENOG4105WFK nuclease BaDB11_00235 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) BaDB11_00237 ENOG4108SVB resolvase BaDB11_00238 ENOG4105VPS UPF0291 protein BaDB11_00239 ENOG4105CV1 Transketolase (EC 2.2.1.1) BaDB11_00241 ENOG4105VXM UPF0154 protein BaDB11_00243 ENOG4107QIV Cytochrome c biogenesis protein BaDB11_00248 ENOG4108I0Z Aconitate hydratase BaDB11_00249 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BaDB11_00254 ENOG4105MI2 BaDB11_00257 ENOG4105W8X HesB YadR YfhF-family protein BaDB11_00258 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BaDB11_00259 ENOG4105K4P CoA-binding domain protein BaDB11_00260 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BaDB11_00262 ENOG4105CMD Transcriptional regulator, GntR family BaDB11_00265 ENOG4105CAC Catalyzes the conversion of L-arabinose to L-ribulose (By similarity) BaDB11_00266 ENOG4107QNK )-transporter BaDB11_00267 ENOG4105CHR reductase BaDB11_00273 ENOG4105R3A Nitrate reductase BaDB11_00274 ENOG4108IUE nitrate reductase beta subunit BaDB11_00281 ENOG4107V6Q Cyclic nucleotide-binding domain BaDB11_00284 ENOG4105IJJ transcriptional regulator, crp fnr family BaDB11_00285 ENOG4105DSQ Nitric oxide reductase BaDB11_00286 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) BaDB11_00287 ENOG4106U2H Protein of unknown function (DUF1360) BaDB11_00288 ENOG4107QWR cellulase (EC 3.2.1.4) BaDB11_00290 ENOG4108428 Inherit from COG: -acetyltransferase BaDB11_00292 ENOG4107UWP Major facilitator superfamily MFS_1 BaDB11_00293 ENOG4108M26 parallel beta-helix repeat protein BaDB11_00295 ENOG4105DQ4 alcohol dehydrogenase BaDB11_00296 ENOG4105VUF Transcriptional regulator BaDB11_00301 ENOG41060WC Enoyl-CoA hydratase BaDB11_00302 ENOG4105C26 Dehydrogenase BaDB11_00303 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BaDB11_00304 ENOG4105C1G acyl-Coa dehydrogenase BaDB11_00305 ENOG4105DG6 mannose-6-phosphate isomerase BaDB11_00306 ENOG4105DM4 PTS System BaDB11_00313 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BaDB11_00314 ENOG4105DMW Dehydrogenase reductase BaDB11_00315 ENOG4105CHZ Catalyzes the dehydration of D-mannonate (By similarity) BaDB11_00317 ENOG4105CG6 trap dicarboxylate transporter dctm subunit BaDB11_00318 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter BaDB11_00319 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit BaDB11_00320 ENOG4107KJX Transcriptional regulator BaDB11_00321 ENOG4108UXE Protein tyrosine phosphatase BaDB11_00322 ENOG4107R5R arsenical pump membrane protein BaDB11_00323 ENOG41082YX Transcriptional regulator, arsr family BaDB11_00324 ENOG4105CZ9 Domain of unknown function (DU1801) BaDB11_00326 ENOG4105CSC Glucose uptake protein BaDB11_00327 ENOG4105F32 YngK protein BaDB11_00330 ENOG4105F1A Pyruvate formate-lyase BaDB11_00332 ENOG4107RVU D-Ala-D-Ala carboxypeptidase 3 (S13) family BaDB11_00338 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BaDB11_00339 ENOG4107QX3 carboxylase BaDB11_00340 ENOG4105E39 Enoyl-CoA hydratase BaDB11_00341 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BaDB11_00342 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BaDB11_00343 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BaDB11_00344 ENOG4105CEY Amp-dependent synthetase and ligase BaDB11_00345 ENOG4105C1G acyl-Coa dehydrogenase BaDB11_00346 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BaDB11_00347 ENOG4105KVH Transcriptional regulator BaDB11_00348 ENOG4105C2S Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity) BaDB11_00349 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) BaDB11_00352 ENOG4105H67 Protein of unknown function (DUF421) BaDB11_00354 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) BaDB11_00355 ENOG41061P3 phosphosulfolactate synthase BaDB11_00357 ENOG4105DIA mandelate racemase muconate lactonizing BaDB11_00358 ENOG4107RCC Major Facilitator Superfamily BaDB11_00362 ENOG4105BZ8 glutamate synthase BaDB11_00363 ENOG4105CBC glutamate synthase BaDB11_00364 ENOG4105C5Q Transcriptional regulator BaDB11_00370 ENOG4105BZ1 (ABC) transporter BaDB11_00373 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BaDB11_00374 ENOG4105C0R drug resistance transporter emrb qaca subfamily BaDB11_00375 ENOG4108J2R molybdopterin oxidoreductase BaDB11_00380 ENOG4108Q8B Spore germination protein BaDB11_00381 ENOG4108NHD germination protein BaDB11_00382 ENOG4108Q8B Spore germination protein BaDB11_00383 ENOG4108Q8B Spore germination protein BaDB11_00386 ENOG4105C8Q Methyl-accepting chemotaxis BaDB11_00387 ENOG4108Z7R Chaperone CsaA BaDB11_00388 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin BaDB11_00390 ENOG4108RZE Tetr family transcriptional regulator BaDB11_00392 ENOG4105T9C HD domain BaDB11_00394 ENOG4105FVX BaDB11_00398 ENOG4108W8B Beta-lactamase domain protein BaDB11_00401 ENOG4105D29 Helix-turn-helix type 11 domain protein BaDB11_00403 ENOG4105KTU Transcriptional regulator, arsr family BaDB11_00406 ENOG4105CUB amino acid BaDB11_00408 ENOG4105C5E polysaccharide biosynthesis protein BaDB11_00411 ENOG4107T8Q Glycosyl transferase (Group 1 BaDB11_00412 ENOG4108SJC Membrane BaDB11_00415 ENOG4107RUZ Sss sodium solute transporter superfamily BaDB11_00416 ENOG41069ER domain protein BaDB11_00417 ENOG4105C9U ATP-dependent DNA helicase RecQ BaDB11_00422 ENOG4105UNS Pfam:DUF419 BaDB11_00425 ENOG4108IEG Formate dehydrogenase Alpha subunit BaDB11_00436 ENOG4108NHD germination protein BaDB11_00439 ENOG4107SYB Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) BaDB11_00442 ENOG4107S9D Alpha beta hydrolase BaDB11_00446 ENOG41082QR Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) BaDB11_00448 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BaDB11_00449 ENOG4105ST3 Transcriptional regulator BaDB11_00453 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BaDB11_00454 ENOG4105SCY DNAK suppressor BaDB11_00457 ENOG4105C26 Dehydrogenase BaDB11_00461 ENOG4105EWU Squalene--hopene cyclase BaDB11_00462 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BaDB11_00464 ENOG4105C8J )-transporter BaDB11_00465 ENOG4105C09 Bile acid BaDB11_00466 ENOG4105C7S Dehydrogenase BaDB11_00467 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 BaDB11_00468 ENOG4107T89 von Willebrand factor, type A BaDB11_00469 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BaDB11_00471 ENOG4105K4H Nlp p60 protein BaDB11_00476 ENOG4105FR1 rard protein BaDB11_00479 ENOG4108YQE rare lipoprotein a BaDB11_00481 ENOG4107EXU Short-chain dehydrogenase reductase Sdr BaDB11_00484 ENOG4105FBA Phospholipase Carboxylesterase BaDB11_00486 ENOG4105E1V na solute symporter BaDB11_00488 ENOG4105DQ6 Transposase BaDB11_00492 ENOG4108VXD carboxy-peptidase BaDB11_00493 ENOG4105D3A purine nucleoside phosphorylase DeoD-type BaDB11_00494 ENOG4108PJD permease BaDB11_00497 ENOG4106Z5R BaDB11_00498 ENOG410841Q phosphoesterase PA-phosphatase related protein BaDB11_00502 ENOG4105VSD UPF0346 protein BaDB11_00504 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BaDB11_00505 ENOG4108TSC N-acetyltransferase BaDB11_00506 ENOG4107S4Y M20 DapE family protein YgeY BaDB11_00509 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BaDB11_00512 ENOG4105E0X reductase BaDB11_00516 ENOG4105BZU Histidine kinase BaDB11_00520 ENOG4105QZP Uncharacterized protein conserved in bacteria (DUF2140) BaDB11_00521 ENOG41090WU lipolytic protein G-D-S-L family BaDB11_00522 ENOG4108KF3 Electron transport protein SCO1 SenC BaDB11_00525 ENOG4105C7B Threonine dehydratase BaDB11_00527 ENOG4108UT2 hemolysin iii BaDB11_00529 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) BaDB11_00532 ENOG4107YX5 Pfam:DUF548 BaDB11_00534 ENOG4105C01 Dihydroxy-acid dehydratase BaDB11_00537 ENOG4108V06 Glutathione peroxidase BaDB11_00538 ENOG4105CKU formyltetrahydrofolate synthetase BaDB11_00539 ENOG4105CVG Homoserine O-transsuccinylase BaDB11_00540 ENOG4108QBV Monogalactosyldiacylglycerol synthase BaDB11_00548 ENOG41081VK Ribonuclease BaDB11_00552 ENOG410890F Dynamin family BaDB11_00554 ENOG41065KQ synthase BaDB11_00555 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BaDB11_00556 ENOG4105C2W permease BaDB11_00557 ENOG4108UPS Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity) BaDB11_00558 ENOG4105CTD carboxy-peptidase BaDB11_00559 ENOG4105DVT helicase BaDB11_00562 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BaDB11_00563 ENOG4105XWG Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity) BaDB11_00564 ENOG4108UKS UPF0398 protein BaDB11_00567 ENOG4107X2U Inherit from COG: Exonuclease-like protein BaDB11_00568 ENOG4108I5C dEAD DEAH box helicase BaDB11_00577 ENOG4105BZ4 penicillin-binding protein BaDB11_00579 ENOG4105CSM endonuclease III BaDB11_00582 ENOG4105CHM Aminotransferase BaDB11_00584 ENOG4105YAC BaDB11_00585 ENOG4105DVT helicase BaDB11_00586 ENOG4108Z2X Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity) BaDB11_00587 ENOG4108IAA Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity) BaDB11_00588 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) BaDB11_00590 ENOG4105D4J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate BaDB11_00591 ENOG4105CPK Glycosyl transferase (Group 1 BaDB11_00592 ENOG4105FJR Lmbe family BaDB11_00593 ENOG4108Z5K methylglyoxal synthase BaDB11_00594 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) BaDB11_00595 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BaDB11_00596 ENOG4108JYZ YitT family BaDB11_00600 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BaDB11_00603 ENOG4108SXZ UPF0302 protein BaDB11_00604 ENOG41068YB TPR repeat-containing protein BaDB11_00607 ENOG4105CIH Imidazole acetol-phosphate transaminase BaDB11_00608 ENOG4105F6H The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity) BaDB11_00609 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) BaDB11_00611 ENOG4105DK0 Indole-3-glycerol phosphate synthase BaDB11_00612 ENOG4108I0Q anthranilate phosphoribosyltransferase BaDB11_00613 ENOG4105CRQ synthase (Component I) BaDB11_00614 ENOG4105KHN chorismate mutase BaDB11_00615 ENOG4105D49 3-dehydroquinate synthase BaDB11_00616 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BaDB11_00617 ENOG4105BZU Histidine kinase BaDB11_00618 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) BaDB11_00619 ENOG4105EAH synthase BaDB11_00620 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BaDB11_00621 ENOG4105XXQ heptaprenyl diphosphate synthase component I BaDB11_00623 ENOG4105EUJ GTP cyclohydrolase i BaDB11_00624 ENOG4105K70 DNA-binding protein BaDB11_00625 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BaDB11_00629 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase BaDB11_00630 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) BaDB11_00631 ENOG41065D1 BaDB11_00632 ENOG4105S2F BaDB11_00635 ENOG4106UJV Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity) BaDB11_00636 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) BaDB11_00637 ENOG4105CAT Cytidine monophosphate kinase BaDB11_00639 ENOG4105MSI germination protein ypeb BaDB11_00642 ENOG4105HDK L-asparaginase BaDB11_00643 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase BaDB11_00646 ENOG4107RGJ metallophosphoesterase BaDB11_00650 ENOG4105I7S Abortive infection protein BaDB11_00651 ENOG4105C9U ATP-dependent DNA helicase RecQ BaDB11_00652 ENOG4105T7X BaDB11_00654 ENOG4108SAX Membrane BaDB11_00655 ENOG4108JQ1 Dehydrogenase BaDB11_00656 ENOG4105DR5 peptidase BaDB11_00662 ENOG4105US7 Histidine kinase BaDB11_00663 ENOG4105BZU Histidine kinase BaDB11_00664 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BaDB11_00665 ENOG4105CRE cytochrome C BaDB11_00666 ENOG4107TWT Cytochrome c biogenesis protein BaDB11_00667 ENOG4108IFH alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BaDB11_00668 ENOG4105FE9 pseudouridine synthase BaDB11_00670 ENOG4108JIC nucleoside recognition domain protein BaDB11_00671 ENOG4105DZ1 carboxypeptidase BaDB11_00673 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) BaDB11_00674 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) BaDB11_00678 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) BaDB11_00679 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) BaDB11_00680 ENOG4108R6K riboflavin synthase, subunit alpha BaDB11_00681 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BaDB11_00683 ENOG4105MEW serine threonine protein phosphatase BaDB11_00684 ENOG4105MYT Heat shock protein BaDB11_00687 ENOG4107ZE5 PPIases accelerate the folding of proteins BaDB11_00688 ENOG4105PTM secreted protein BaDB11_00689 ENOG4105K7W phage-related replication protein BaDB11_00690 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BaDB11_00693 ENOG4105G6R Stage v sporulation protein ae BaDB11_00695 ENOG4105CZ3 stage V sporulation protein ad BaDB11_00696 ENOG41090VF Stage v sporulation protein ac BaDB11_00699 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BaDB11_00700 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) BaDB11_00701 ENOG41082AN stage II sporulation protein BaDB11_00702 ENOG4105DZ1 carboxypeptidase BaDB11_00703 ENOG4105CB1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) BaDB11_00704 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) BaDB11_00705 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BaDB11_00707 ENOG4105I3K Ferric uptake regulator, Fur family BaDB11_00708 ENOG4105MZ9 stage II sporulation protein m BaDB11_00709 ENOG4105CK1 PTS System BaDB11_00711 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease BaDB11_00712 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease BaDB11_00715 ENOG4107YB6 acetyltransferase, (GNAT) family BaDB11_00717 ENOG4108YZ4 nudix hydrolase BaDB11_00719 ENOG4105PF9 Transcriptional regulator BaDB11_00721 ENOG4105CPC Aldo Keto reductase BaDB11_00725 ENOG4106HZJ BaDB11_00727 ENOG4105RHY Pfam:UPF0157 BaDB11_00728 ENOG4105KAC Antibiotic biosynthesis monooxygenase BaDB11_00729 ENOG4108KTS Acetyltransferase and hydrolase with the alpha beta hydrolase fold BaDB11_00731 ENOG4107RRN ABC transporter substrate-binding protein BaDB11_00732 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BaDB11_00733 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BaDB11_00734 ENOG4108RZA ABC transporter BaDB11_00736 ENOG4107R73 Mate efflux family protein BaDB11_00740 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BaDB11_00742 ENOG4105E5W Transporter BaDB11_00743 ENOG4105HRU Glyoxalase Bleomycin resistance protein (Dioxygenase BaDB11_00746 ENOG4105DA5 (ABC) transporter BaDB11_00750 ENOG4105K7W phage-related replication protein BaDB11_00751 ENOG4108IXY short-chain dehydrogenase reductase BaDB11_00752 ENOG41069FQ Metallo-beta-lactamase superfamily BaDB11_00753 ENOG4105II7 pyrroline-5-carboxylate reductase BaDB11_00755 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BaDB11_00757 ENOG4105WDJ 50S ribosomal protein L33 BaDB11_00758 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BaDB11_00759 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BaDB11_00763 ENOG4108TZY GntR Family Transcriptional Regulator BaDB11_00764 ENOG4105CS2 ec 3.2.1.21 BaDB11_00765 ENOG4105CK1 PTS System BaDB11_00766 ENOG4105VCP PTS System BaDB11_00767 ENOG4105VZJ PTS System BaDB11_00768 ENOG4105G6Z alkaline phosphatase BaDB11_00769 ENOG4105H9W Short-chain dehydrogenase reductase Sdr BaDB11_00770 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BaDB11_00771 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BaDB11_00773 ENOG4107XQC Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity) BaDB11_00774 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BaDB11_00775 ENOG4108HNZ carboxyl transferase BaDB11_00776 ENOG4108QEG Membrane BaDB11_00777 ENOG4105CDA abc transporter atp-binding protein BaDB11_00778 ENOG4105E5Q amino acid AbC transporter BaDB11_00779 ENOG4108HW3 (ABC) transporter BaDB11_00781 ENOG4108Y6J UPF0403 protein BaDB11_00782 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) BaDB11_00783 ENOG4105C7S Dehydrogenase BaDB11_00784 ENOG4105CPP Dehydrogenase, E1 component BaDB11_00787 ENOG4105CKM Branched-chain carboxylic acid kinase BaDB11_00788 ENOG4107RDP Dehydrogenase BaDB11_00790 ENOG4108JUB Transcriptional regulator BaDB11_00791 ENOG4106CCJ Protein of unknown function (DUF2627) BaDB11_00792 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BaDB11_00793 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BaDB11_00796 ENOG4105D7W serine acetyltransferase BaDB11_00798 ENOG4107QQR Sporulation BaDB11_00799 ENOG4105S1Z Stage IV sporulation protein B BaDB11_00800 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BaDB11_00801 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) BaDB11_00802 ENOG4105DX0 Hemolysin A BaDB11_00803 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) BaDB11_00804 ENOG4105CTB Polyprenyl synthetase BaDB11_00805 ENOG41067QG Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) BaDB11_00806 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) BaDB11_00807 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) BaDB11_00808 ENOG4105M7K Involved in the transcription termination process (By similarity) BaDB11_00809 ENOG4108ZSR alkaline shock protein BaDB11_00810 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BaDB11_00814 ENOG410644B Stage III sporulation protein af BaDB11_00816 ENOG4105KQ4 Stage iii sporulation protein ad BaDB11_00817 ENOG4108CQH stage III sporulation protein AC BaDB11_00818 ENOG4105KR5 Stage iii sporulation protein BaDB11_00819 ENOG4105CD2 stage iii sporulation protein aa BaDB11_00821 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) BaDB11_00822 ENOG4105DC7 peptidase M24 BaDB11_00823 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) BaDB11_00825 ENOG4105CBJ Metal-dependent enzyme BaDB11_00828 ENOG4105KST dependent repressor BaDB11_00829 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) BaDB11_00830 ENOG4105WZW rhodanese family BaDB11_00832 ENOG4107SQ8 Glycine betaine BaDB11_00833 ENOG4108IJ7 Glycine betaine BaDB11_00834 ENOG4107RGW The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor BaDB11_00836 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) BaDB11_00837 ENOG4105C0D helicase BaDB11_00842 ENOG4105VFR signal peptidase BaDB11_00849 ENOG4106855 Competence protein BaDB11_00855 ENOG4105C5X domain protein BaDB11_00862 ENOG4105E0M Sulfatase BaDB11_00865 ENOG4107ZXI Rhomboid family BaDB11_00867 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BaDB11_00868 ENOG4105WDJ 50S ribosomal protein L33 BaDB11_00872 ENOG41068DG YceG-like family BaDB11_00873 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BaDB11_00874 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BaDB11_00875 ENOG4105E2Z phosphate ABC transporter (Permease BaDB11_00876 ENOG4105C8U phosphate abc transporter BaDB11_00877 ENOG4105CVA phosphate BaDB11_00878 ENOG4107RF6 penicillin-binding protein BaDB11_00880 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BaDB11_00881 ENOG4105SXS Protein of unknown function (DUF456) BaDB11_00884 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) BaDB11_00885 ENOG41063Y9 BaDB11_00886 ENOG4108U5J '-nucleotidase BaDB11_00887 ENOG4105N80 Ferric uptake regulator, Fur family BaDB11_00888 ENOG4105FAV ABC, transporter BaDB11_00889 ENOG4105FDK ABC transporter BaDB11_00890 ENOG4108JYZ YitT family BaDB11_00891 ENOG41069ZM Protein of unknown function (DUF2624) BaDB11_00892 ENOG4105EFU Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity) BaDB11_00895 ENOG4105C48 Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) BaDB11_00896 ENOG4105EGD dinuclear metal center protein, YbgI family BaDB11_00898 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) BaDB11_00899 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) BaDB11_00911 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BaDB11_00912 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BaDB11_00914 ENOG4105CF9 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity) BaDB11_00916 ENOG4105C38 Glycyl-tRNA synthetase beta subunit BaDB11_00917 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit BaDB11_00918 ENOG4108SAY Involved in DNA repair and RecF pathway recombination (By similarity) BaDB11_00920 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BaDB11_00921 ENOG4105KG3 cytidine deaminase BaDB11_00922 ENOG4107YR5 Diacylglycerol kinase BaDB11_00923 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) BaDB11_00924 ENOG4105CTJ Metal Dependent Phosphohydrolase BaDB11_00925 ENOG4105C9A Phoh family BaDB11_00926 ENOG4105EI1 sporulation protein yqfd BaDB11_00927 ENOG41068P3 sporulation protein YqfC BaDB11_00929 ENOG4105DI5 UPF0365 protein BaDB11_00930 ENOG4105F7J membrane-bound serine protease BaDB11_00931 ENOG4105KTH gatB Yqey BaDB11_00932 ENOG4105VCC 30S ribosomal protein S21 BaDB11_00934 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) BaDB11_00935 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BaDB11_00936 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BaDB11_00937 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) BaDB11_00938 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) BaDB11_00939 ENOG4105CFG Acts as a chaperone (By similarity) BaDB11_00940 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ BaDB11_00941 ENOG4105CI8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity) BaDB11_00942 ENOG4105CSA Coproporphyrinogen iii oxidase BaDB11_00943 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) BaDB11_00945 ENOG4108ZRV stage ii sporulation protein p BaDB11_00948 ENOG4105TQK DNA polymerase iii, delta' subunit BaDB11_00950 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BaDB11_00951 ENOG4108UK2 deaminase BaDB11_00952 ENOG4105KQC Competence protein BaDB11_00954 ENOG4108D32 Methyltransferase BaDB11_00956 ENOG4108WF2 Metal Dependent Phosphohydrolase BaDB11_00957 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) BaDB11_00958 ENOG410812S Rna-binding protein BaDB11_00959 ENOG4105E2X shikimate dehydrogenase BaDB11_00960 ENOG4105CQW ribosome biogenesis GTPase YqeH BaDB11_00961 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BaDB11_00964 ENOG4105Z7P Acetyltransferase (GNAT) family BaDB11_00965 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BaDB11_00966 ENOG4108JB9 formate dehydrogenase BaDB11_00969 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BaDB11_00975 ENOG4108ZRV stage ii sporulation protein p BaDB11_00978 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BaDB11_00989 ENOG4105WH1 Two component transcriptional regulator luxr family BaDB11_00990 ENOG4105BZU Histidine kinase BaDB11_00991 ENOG4105XXY Thioredoxin BaDB11_00992 ENOG41087NI Sulfite exporter TauE/SafE BaDB11_00993 ENOG4105VFE sira family BaDB11_00994 ENOG4107TPS domain protein BaDB11_00995 ENOG4105VFE sira family BaDB11_00996 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase BaDB11_00997 ENOG4105XTG Pfam:DUF156 BaDB11_00998 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) BaDB11_01001 ENOG4105VAS Could be involved in insertion of integral membrane proteins into the membrane (By similarity) BaDB11_01003 ENOG41080HJ 6-phospho 3-hexuloisomerase BaDB11_01004 ENOG4108VA3 3-hexulose-6-phosphate synthase BaDB11_01005 ENOG4105KVH Transcriptional regulator BaDB11_01006 ENOG4105ECK Fatty Acid Desaturase BaDB11_01007 ENOG4108ZGX Histidine kinase BaDB11_01008 ENOG4108S01 response regulator BaDB11_01009 ENOG4105CAY ferredoxin--nadp reductase BaDB11_01010 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein BaDB11_01011 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BaDB11_01012 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BaDB11_01014 ENOG4108JQ7 (ABC) transporter BaDB11_01017 ENOG4108ZX5 transcriptional regulator BaDB11_01018 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BaDB11_01022 ENOG410635A Membrane BaDB11_01024 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BaDB11_01025 ENOG4108HKT sucrose-6-phosphate hydrolase BaDB11_01026 ENOG4105F3R pts system mannose fructose sorbose family iid BaDB11_01027 ENOG4105ETZ PTS System BaDB11_01028 ENOG4108IQ3 PTS system BaDB11_01029 ENOG4105YHU PTS system BaDB11_01030 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BaDB11_01032 ENOG4105WDR BaDB11_01035 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BaDB11_01036 ENOG4105CV8 reductase BaDB11_01037 ENOG4105F27 Major Facilitator BaDB11_01038 ENOG4105KVH Transcriptional regulator BaDB11_01039 ENOG4105EQ6 Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity) BaDB11_01040 ENOG4105EXQ uroporphyrinogen iii synthase hem4 BaDB11_01042 ENOG4108V5C ABC transporter BaDB11_01043 ENOG4107RSM transcriptional regulator BaDB11_01044 ENOG4105D94 Major Facilitator Superfamily BaDB11_01046 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BaDB11_01047 ENOG41082JN Transcriptional regulator BaDB11_01048 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin BaDB11_01053 ENOG4105C28 cystathionine BaDB11_01055 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BaDB11_01056 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) BaDB11_01059 ENOG4107XRG penicillin-binding protein BaDB11_01060 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) BaDB11_01062 ENOG4105CFP Peptidase U32 BaDB11_01063 ENOG4105XYU peptidase (U32 family) BaDB11_01064 ENOG4108VQJ O-methyltransferase BaDB11_01065 ENOG4105HHA aminodeoxychorismate lyase BaDB11_01066 ENOG4105VPH UPF0473 protein BaDB11_01067 ENOG4108Z08 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) BaDB11_01068 ENOG4105VBH UPF0297 protein BaDB11_01069 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BaDB11_01070 ENOG4105C02 permease BaDB11_01071 ENOG41060CR BaDB11_01073 ENOG4105C7H Helicase, RecD TraA family BaDB11_01075 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) BaDB11_01076 ENOG4105C3J Cysteine desulfurase BaDB11_01078 ENOG4105D1H recombination factor protein RarA BaDB11_01079 ENOG4105CUZ uba thif-type nad fad binding protein BaDB11_01080 ENOG4105C9M aspartyl-trna synthetase BaDB11_01081 ENOG4105CUT histidyl-tRNA synthetase BaDB11_01083 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BaDB11_01084 ENOG4108YYA Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity) BaDB11_01085 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BaDB11_01086 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) BaDB11_01087 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BaDB11_01088 ENOG41067VP Protein of unknown function (DUF1049) BaDB11_01089 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BaDB11_01091 ENOG4105CKP Polysaccharide Biosynthesis Protein BaDB11_01092 ENOG4108QG2 Membrane BaDB11_01093 ENOG4105NAP BaDB11_01094 ENOG4105VIE preprotein translocase, subunit YajC BaDB11_01095 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) BaDB11_01096 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) BaDB11_01097 ENOG41061AI Protein of unknown function (DUF2905) BaDB11_01098 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) BaDB11_01099 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) BaDB11_01103 ENOG41069DP small acid-soluble spore protein BaDB11_01105 ENOG4105K7W phage-related replication protein BaDB11_01108 ENOG4105CDY transcriptional regulatory protein BaDB11_01110 ENOG4106678 morphogenetic protein associated with SpoVID BaDB11_01111 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) BaDB11_01112 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BaDB11_01113 ENOG4108IYU L-aspartate oxidase BaDB11_01116 ENOG4105CQC Prephenate dehydratase BaDB11_01117 ENOG41090I5 UPF0735 ACT domain-containing protein BaDB11_01118 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control BaDB11_01120 ENOG4105K46 50S ribosomal protein l27 BaDB11_01121 ENOG4105X36 (ribosomal) protein BaDB11_01122 ENOG4105KK9 This protein binds to 23S rRNA in the presence of protein L20 (By similarity) BaDB11_01126 ENOG41082BM Transcriptional regulator, arsr family BaDB11_01127 ENOG4107QMS site-determining protein BaDB11_01128 ENOG4107YDG Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity) BaDB11_01129 ENOG4105YHC Rod shape-determining protein MreD BaDB11_01130 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BaDB11_01131 ENOG4105DFF Rod shape-determining protein mreb BaDB11_01132 ENOG4105W5Q DNA repair protein (RadC BaDB11_01133 ENOG4108Z03 MAF-like protein BaDB11_01135 ENOG4106A3R peptidase BaDB11_01136 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BaDB11_01137 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) BaDB11_01139 ENOG4106AR7 Spore coat protein BaDB11_01140 ENOG41068KH stage VI sporulation protein D BaDB11_01141 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase BaDB11_01142 ENOG4105D52 delta-aminolevulinic acid dehydratase BaDB11_01144 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) BaDB11_01146 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) BaDB11_01148 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) BaDB11_01149 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) BaDB11_01150 ENOG4108IUQ atp-dependent protease BaDB11_01151 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) BaDB11_01152 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation BaDB11_01154 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) BaDB11_01155 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) BaDB11_01156 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BaDB11_01157 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) BaDB11_01158 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BaDB11_01159 ENOG4108ZP8 Acetolactate synthase small subunit BaDB11_01160 ENOG4105C7K acetolactate synthase BaDB11_01161 ENOG4105CM2 brancheD-chain amino acid aminotransferase BaDB11_01163 ENOG4107R37 Glutamate dehydrogenase BaDB11_01166 ENOG4108MDF Phage Portal Protein BaDB11_01167 ENOG4105IG6 Phage terminase, large subunit BaDB11_01175 ENOG4107EV6 Inherit from COG: YD repeat protein BaDB11_01181 ENOG4105M59 Phosphodiesterase, mj0936 family BaDB11_01182 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BaDB11_01183 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) BaDB11_01184 ENOG4108XJQ germination protein BaDB11_01185 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BaDB11_01186 ENOG41067TZ transcriptional regulator, MarR family BaDB11_01187 ENOG4105PFC Transcriptional regulator BaDB11_01188 ENOG4105EMU Dehydrogenase BaDB11_01190 ENOG4105E33 succinate dehydrogenase BaDB11_01192 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BaDB11_01194 ENOG4105CFH Aspartokinase BaDB11_01195 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BaDB11_01196 ENOG4105K63 Thioredoxin BaDB11_01197 ENOG4105C10 Electron transfer flavoprotein BaDB11_01198 ENOG4105BZJ Electron transfer flavoprotein BaDB11_01199 ENOG41060WC Enoyl-CoA hydratase BaDB11_01200 ENOG4107Z3H Transcriptional regulator, TetR family BaDB11_01201 ENOG4105CEY Amp-dependent synthetase and ligase BaDB11_01203 ENOG4105C98 muts2 protein BaDB11_01204 ENOG4105DCG PHP domain protein BaDB11_01206 ENOG410687F Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity) BaDB11_01207 ENOG4107FSS Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) BaDB11_01209 ENOG4105DQ6 Transposase BaDB11_01213 ENOG4108IUZ ABC transporter BaDB11_01216 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) BaDB11_01217 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) BaDB11_01218 ENOG4108RWN rrna methyltransferase BaDB11_01219 ENOG41067MF small acid-soluble spore protein BaDB11_01223 ENOG4105DRS transport system, permease BaDB11_01226 ENOG4108MDK Dehydrogenase BaDB11_01227 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase BaDB11_01228 ENOG4105EF1 ribulokinase BaDB11_01229 ENOG4105CAC Catalyzes the conversion of L-arabinose to L-ribulose (By similarity) BaDB11_01230 ENOG4105CAC Catalyzes the conversion of L-arabinose to L-ribulose (By similarity) BaDB11_01231 ENOG4107PMW Arabinan endo-1,5-alpha-L-arabinosidase BaDB11_01232 ENOG4105CN9 Peptidase m42 family protein BaDB11_01234 ENOG410696E Membrane BaDB11_01235 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) BaDB11_01236 ENOG4105VJV 50s ribosomal protein L35 BaDB11_01237 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BaDB11_01238 ENOG41067MG lrgb family BaDB11_01240 ENOG4105DGI Alkaline phosphatase BaDB11_01241 ENOG4105DY9 regulatoR BaDB11_01242 ENOG4108HRK Histidine kinase BaDB11_01244 ENOG4105U0R haloacid dehalogenase-like hydrolase BaDB11_01245 ENOG4105C22 threonyL-tRNA synthetase BaDB11_01246 ENOG4108TDW sporulation protein YtxC BaDB11_01250 ENOG4108Z11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity) BaDB11_01252 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BaDB11_01253 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BaDB11_01254 ENOG4108NR7 pectate lyase BaDB11_01255 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BaDB11_01257 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) BaDB11_01258 ENOG4105C2M dna polymerase I BaDB11_01259 ENOG4105BZU Histidine kinase BaDB11_01260 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BaDB11_01261 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BaDB11_01262 ENOG4108HMX isocitrate dehydrogenase (NADP) BaDB11_01263 ENOG4105BZN citrate synthase BaDB11_01264 ENOG4108VMM UPF0756 membrane protein BaDB11_01265 ENOG4108REF Sporulation integral membrane protein ytvi BaDB11_01266 ENOG4105FS0 cytoplasmic membrane protein BaDB11_01267 ENOG4105CA9 Pyruvate kinase BaDB11_01268 ENOG4105CTQ phosphohexokinase BaDB11_01269 ENOG4107QM9 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity) BaDB11_01271 ENOG4105C6K Malic enzyme BaDB11_01272 ENOG4105C0B DNA polymerase III (alpha subunit) BaDB11_01273 ENOG4105VV2 BaDB11_01275 ENOG4106EVM BaDB11_01276 ENOG4105SFS phosphoesterase RecJ domain protein BaDB11_01279 ENOG4105U3E Transcriptional regulator BaDB11_01280 ENOG4105E8R UPF0173 metal-dependent hydrolase BaDB11_01283 ENOG4105CH7 arginosuccinase BaDB11_01284 ENOG4105CDH Citrulline--aspartate ligase BaDB11_01285 ENOG4105EPU Molybdenum cofactor synthesis domain protein BaDB11_01286 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) BaDB11_01288 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BaDB11_01289 ENOG4105KBJ sporulation protein ytfj BaDB11_01291 ENOG4105VK3 rdd domain containing protein BaDB11_01292 ENOG4105D07 Signal peptide peptidase, SppA BaDB11_01295 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BaDB11_01297 ENOG4105D8I Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity) BaDB11_01302 ENOG4105U5Y Transcriptional regulator BaDB11_01304 ENOG4105BZU Histidine kinase BaDB11_01305 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) BaDB11_01308 ENOG4105KAF membrAne BaDB11_01309 ENOG4105IGJ Zn-dependent Hydrolase of the beta-lactamase fold protein BaDB11_01312 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BaDB11_01314 ENOG4105F1V Acetoin utilization protein BaDB11_01315 ENOG4105W87 Cbs domain BaDB11_01316 ENOG4105DGU Histone deacetylase BaDB11_01317 ENOG4105ER2 Ompa motb domain protein BaDB11_01318 ENOG4107R0U MotA TolQ exbB proton channel BaDB11_01319 ENOG4105ETE Transcriptional regulator (LacI family BaDB11_01320 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BaDB11_01326 ENOG4105DFU Cell wall formation (By similarity) BaDB11_01328 ENOG4108VDD TRNA binding domain protein BaDB11_01331 ENOG4108V0E nucleoside 2-deoxyribosyltransferase YtoQ BaDB11_01334 ENOG4105C6K Malic enzyme BaDB11_01335 ENOG4105C8F Beta-lactamase domain protein BaDB11_01336 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) BaDB11_01338 ENOG4108V15 phosphotransferase enzyme family BaDB11_01339 ENOG4108IUM Glycogen debranching enzyme BaDB11_01342 ENOG4107F58 2'-5' rna ligase BaDB11_01343 ENOG4105C6T cysteine synthase BaDB11_01346 ENOG4107QSE Dipeptidase BaDB11_01347 ENOG4105C7N Xanthine uracil vitamin C permease BaDB11_01348 ENOG4105YW5 deoR family transcriptional regulator BaDB11_01351 ENOG4105CBX hi0933 family BaDB11_01352 ENOG4105C94 Transporter BaDB11_01354 ENOG41085GJ domain protein BaDB11_01358 ENOG4105MU9 integral membrane protein BaDB11_01359 ENOG4105DDC Oxidoreductase domain protein BaDB11_01361 ENOG4105F5H Glycosyl Hydrolase Family 88 BaDB11_01363 ENOG41075H3 AraC family transcriptional regulator BaDB11_01365 ENOG4105C50 Binding-protein-dependent transport systems, inner membrane component BaDB11_01367 ENOG4105NTD Inherit from COG: Hydrolase BaDB11_01369 ENOG4107V2S Transcriptional regulator BaDB11_01370 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BaDB11_01371 ENOG4105C8T Leucyl-tRNA synthetase BaDB11_01373 ENOG410605W Major Facilitator BaDB11_01374 ENOG4105D01 (LipO)protein BaDB11_01375 ENOG4106UBQ BaDB11_01376 ENOG4107R34 abc transporter permease protein BaDB11_01377 ENOG4105C19 ABC transporter BaDB11_01379 ENOG4105DVE abc transporter atp-binding protein BaDB11_01380 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BaDB11_01383 ENOG4105N5T Radical SAM Protein BaDB11_01387 ENOG4105E8V Alpha Beta Hydrolase Fold protein BaDB11_01388 ENOG4108Z0R Transferase BaDB11_01389 ENOG4105YVM Phosphoesterase, PA-phosphatase related BaDB11_01390 ENOG4105BZF Glycosyl transferase (Group 1 BaDB11_01391 ENOG4105CAQ asparagine synthetase BaDB11_01392 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP BaDB11_01397 ENOG4105D2X ABC transporter substrate-binding protein BaDB11_01399 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component BaDB11_01403 ENOG4108RMU ferritin dps family protein BaDB11_01406 ENOG4106762 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity) BaDB11_01407 ENOG4105VAS Could be involved in insertion of integral membrane proteins into the membrane (By similarity) BaDB11_01408 ENOG4108V2W Carbonate dehydratase BaDB11_01409 ENOG4105CKI cobalamin synthesis protein BaDB11_01410 ENOG4105DSE periplasmic solute binding protein BaDB11_01416 ENOG4105DTQ mandelate racemase muconate lactonizing BaDB11_01417 ENOG4105CEY Amp-dependent synthetase and ligase BaDB11_01418 ENOG4108IPT Naphthoate synthase BaDB11_01419 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BaDB11_01420 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) BaDB11_01421 ENOG4105E4F Isochorismate synthase BaDB11_01422 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BaDB11_01425 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) BaDB11_01427 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) BaDB11_01428 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) BaDB11_01429 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) BaDB11_01454 ENOG4105CMD Transcriptional regulator, GntR family BaDB11_01455 ENOG4105N67 Proton-coupled thiamine transporter YuaJ BaDB11_01461 ENOG4108KN7 Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity) BaDB11_01463 ENOG4105CZN Potassium uptake protein BaDB11_01465 ENOG4106DF1 BaDB11_01466 ENOG4108VNY MOSC domain protein BaDB11_01467 ENOG4108JB8 alcohol dehydrogenase BaDB11_01468 ENOG4105C26 Dehydrogenase BaDB11_01469 ENOG4105TRT Transcriptional regulator BaDB11_01471 ENOG4105JQZ Methyltransferase BaDB11_01472 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BaDB11_01473 ENOG4105F0F Oxalate decarboxylase BaDB11_01481 ENOG4105VES Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) BaDB11_01487 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BaDB11_01489 ENOG4105EE0 oxidoreductase BaDB11_01490 ENOG4108Z0Z intracellular protease Pfpi family BaDB11_01491 ENOG4105C8Q Methyl-accepting chemotaxis BaDB11_01492 ENOG4105C8Q Methyl-accepting chemotaxis BaDB11_01493 ENOG4105C8Q Methyl-accepting chemotaxis BaDB11_01495 ENOG4105EA8 2-Nitropropane dioxygenase BaDB11_01496 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme BaDB11_01501 ENOG4105C37 (CBS) domain BaDB11_01504 ENOG4107PBV potassium channel BaDB11_01505 ENOG4107PBV potassium channel BaDB11_01507 ENOG410900G Protein of unknown function (DUF421) BaDB11_01509 ENOG4105KNA -acetyltransferase BaDB11_01510 ENOG4107QYV phosphohexose isomerase BaDB11_01511 ENOG4107QW4 alcohol dehydrogenase BaDB11_01512 ENOG4105WG9 Conserved Protein BaDB11_01514 ENOG4105CHM Aminotransferase BaDB11_01515 ENOG4108ZB6 transcriptional regulator AsnC family BaDB11_01516 ENOG4108MUZ hydrolase BaDB11_01519 ENOG4105C87 Aminotransferase class I and II BaDB11_01521 ENOG4105Y38 Kinase-associated protein B BaDB11_01524 ENOG4105BZ4 penicillin-binding protein BaDB11_01525 ENOG4105KIR Thiol-disulfide oxidoreductase dcc BaDB11_01528 ENOG4108MRH transcriptional regulatory protein BaDB11_01529 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BaDB11_01530 ENOG4107ZTW SNARE associated Golgi BaDB11_01531 ENOG4105DJ4 phosphatidylserine decarboxylase BaDB11_01534 ENOG4105D65 subunit l BaDB11_01535 ENOG4105HC0 Na H antiporter BaDB11_01536 ENOG4108ZE9 Monovalent cation H antiporter subunit C BaDB11_01537 ENOG4108JPZ Monovalent cation H antiporter subunit D BaDB11_01538 ENOG4105SC1 monovalent cation H antiporter subunit E BaDB11_01540 ENOG4105KJM monovalent cation h antiporter subunit g BaDB11_01541 ENOG4105KA0 thioesterase Superfamily protein BaDB11_01543 ENOG4105BZU Histidine kinase BaDB11_01549 ENOG4105D58 Diguanylate phosphodiesterase BaDB11_01550 ENOG4105DAP Nicotinate phosphoribosyltransferase BaDB11_01555 ENOG4105C02 permease BaDB11_01556 ENOG4108Z40 Transcriptional regulator BaDB11_01560 ENOG410904N short-chain dehydrogenase reductase BaDB11_01567 ENOG4105BZG amino acid carrier protein BaDB11_01568 ENOG4108K8K Transcriptional regulator BaDB11_01569 ENOG4105DCF alanine dehydrogenase BaDB11_01574 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) BaDB11_01576 ENOG41069ER domain protein BaDB11_01578 ENOG4105CEP NADH dehydrogenase BaDB11_01579 ENOG4105CAY ferredoxin--nadp reductase BaDB11_01582 ENOG4108YM7 Gcn5-related n-acetyltransferase BaDB11_01583 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BaDB11_01588 ENOG4108ZMX Domain of unknown function (DU1801) BaDB11_01591 ENOG4105PY6 Phenolic acid decarboxylase BaDB11_01594 ENOG41083MR nifu domain-containing protein BaDB11_01595 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein BaDB11_01596 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) BaDB11_01597 ENOG4108IYI Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity) BaDB11_01598 ENOG4105D6E homoserine dehydrogenase BaDB11_01599 ENOG4105C5I Dehydrogenase BaDB11_01601 ENOG4108W5N phosphatidylglycerophosphatase a BaDB11_01602 ENOG4105D4U had-superfamily hydrolase, subfamily iia BaDB11_01604 ENOG4105MMD transcriptional regulator BaDB11_01605 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BaDB11_01606 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) BaDB11_01607 ENOG4105FAA peptidase M23 BaDB11_01609 ENOG4105C8J )-transporter BaDB11_01610 ENOG4108YTE sporulation protein YunB BaDB11_01611 ENOG4105KZD Domain of unknown function (DUF1805) BaDB11_01612 ENOG4107R8B 5'-nucleotidase BaDB11_01614 ENOG4105I3N Conserved Protein BaDB11_01615 ENOG4105IIP Membrane BaDB11_01616 ENOG4105W1N transcriptional regulator BaDB11_01618 ENOG4105C5R Aminotransferase BaDB11_01620 ENOG4105G9B Transcriptional regulator BaDB11_01623 ENOG4108I0Q anthranilate phosphoribosyltransferase BaDB11_01624 ENOG4108I0Q anthranilate phosphoribosyltransferase BaDB11_01625 ENOG4108K8S endonuclease I BaDB11_01627 ENOG4107VFR oxidoreductase BaDB11_01632 ENOG4105DIW FeS assembly protein SUFB BaDB11_01633 ENOG4108UNV SUF system FeS assembly protein, NifU family BaDB11_01634 ENOG4105C9B Cysteine desulfurase BaDB11_01635 ENOG4105JRK feS assembly protein SufD BaDB11_01636 ENOG4105C3K feS assembly ATPase SufC BaDB11_01637 ENOG4105PGM cation diffusion facilitator family transporter BaDB11_01639 ENOG4105D01 (LipO)protein BaDB11_01640 ENOG4108UMI ABC transporter, permease BaDB11_01641 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BaDB11_01646 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) BaDB11_01647 ENOG41080E8 Transcriptional regulator, Spx MgsR family BaDB11_01648 ENOG4105C1G acyl-Coa dehydrogenase BaDB11_01649 ENOG4105CHU acetyl-coa acetyltransferase BaDB11_01656 ENOG4105E0A ABC, transporter BaDB11_01657 ENOG4108IHU transport system permease protein BaDB11_01658 ENOG4105DQ5 transport system permease protein BaDB11_01659 ENOG4108MES Periplasmic binding protein BaDB11_01662 ENOG4105DZ1 carboxypeptidase BaDB11_01663 ENOG4105E1F short-chain dehydrogenase reductase BaDB11_01664 ENOG4105HUF DNA protection during starvation protein BaDB11_01665 ENOG4105C0H protease BaDB11_01667 ENOG4105F3H Histidine kinase BaDB11_01669 ENOG41067SE Tetr family transcriptional regulator BaDB11_01670 ENOG4105C9Q fumarate hydratase class II BaDB11_01676 ENOG4105WH1 Two component transcriptional regulator luxr family BaDB11_01677 ENOG4105ENE Histidine kinase BaDB11_01680 ENOG41087YS Phage shock protein A BaDB11_01683 ENOG4108WBT adenosyltransferase BaDB11_01684 ENOG4105CHR reductase BaDB11_01685 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) BaDB11_01686 ENOG4105C0A alcohol dehydrogenase BaDB11_01687 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BaDB11_01688 ENOG4105E0A ABC, transporter BaDB11_01689 ENOG4105EHG Permease protein BaDB11_01690 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) BaDB11_01691 ENOG4105DRR Transcriptional regulator, GntR family BaDB11_01692 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BaDB11_01693 ENOG4108RPX mosc domain containing protein BaDB11_01694 ENOG4105DND Transcriptional regulator BaDB11_01696 ENOG4105CTX dehydratase BaDB11_01697 ENOG4107QZW Altronate oxidoreductase BaDB11_01698 ENOG4107KJX Transcriptional regulator BaDB11_01699 ENOG4105CT4 transporter BaDB11_01700 ENOG4105D2H Uronic isomerase BaDB11_01702 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BaDB11_01703 ENOG4105E0A ABC, transporter BaDB11_01704 ENOG4105EHG Permease protein BaDB11_01705 ENOG4105DQ5 transport system permease protein BaDB11_01706 ENOG4105D5Q Arginine ornithine antiporter BaDB11_01707 ENOG4107K5X Membrane-bound metal-dependent hydrolase BaDB11_01708 ENOG4107QZ2 Sulfatase BaDB11_01711 ENOG4105EVU fructokinase BaDB11_01712 ENOG4107EPV Aminotransferase class V BaDB11_01714 ENOG4105EEM helicase BaDB11_01715 ENOG4105EN6 Membrane BaDB11_01716 ENOG4105RHY Pfam:UPF0157 BaDB11_01718 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BaDB11_01720 ENOG4107ZQN disulfide bond BaDB11_01721 ENOG4105C59 p-type ATPase BaDB11_01722 ENOG4108JE9 extracellular solute-binding protein family 1 BaDB11_01723 ENOG4105F0P binding-protein-dependent transport systems inner membrane Component BaDB11_01724 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component BaDB11_01725 ENOG4105CJQ hydrolase, family 31 BaDB11_01727 ENOG4105DIK (ABC) transporter BaDB11_01728 ENOG4105CC5 ABC transporter BaDB11_01729 ENOG4105DSE periplasmic solute binding protein BaDB11_01731 ENOG4105HX0 Transcriptional regulator BaDB11_01732 ENOG4105DW0 Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity) BaDB11_01733 ENOG4105DM4 PTS System BaDB11_01737 ENOG4105C59 p-type ATPase BaDB11_01738 ENOG410681U heavy metal transport detoxification protein BaDB11_01739 ENOG4105VPX protein, conserved in bacteria BaDB11_01740 ENOG4107RKG DJ-1/PfpI family BaDB11_01741 ENOG4105E98 transcriptional regulator DeoR family BaDB11_01742 ENOG4105DET Rhamnulokinase BaDB11_01743 ENOG4105C9F isomerase BaDB11_01746 ENOG4105F27 Major Facilitator BaDB11_01748 ENOG410625E BaDB11_01749 ENOG4106A3M Cytochrome p-450 BaDB11_01753 ENOG4105D9R oxidoreductase BaDB11_01756 ENOG4105C72 UPF0176 protein BaDB11_01758 ENOG4106DF4 Sigma-70, region 4 BaDB11_01760 ENOG4105F0F Oxalate decarboxylase BaDB11_01767 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) BaDB11_01772 ENOG4107EV6 Inherit from COG: YD repeat protein BaDB11_01779 ENOG41068G1 BaDB11_01781 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj BaDB11_01783 ENOG4108FKH Transglycosylase SLT domain BaDB11_01792 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BaDB11_01795 ENOG4105CAR Terminase, large subunit BaDB11_01826 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) BaDB11_01827 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BaDB11_01829 ENOG4105XZU Preprotein translocase, subunit SecG BaDB11_01834 ENOG4105R40 Glycine betaine carnitine choline BaDB11_01835 ENOG4108HQR Glycine betaine BaDB11_01836 ENOG4105E90 ABC transporter BaDB11_01837 ENOG4108IJ8 ABC transporter BaDB11_01838 ENOG4107HG4 Transcriptional regulator BaDB11_01839 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein BaDB11_01841 ENOG4105T65 Membrane-associated protein BaDB11_01843 ENOG4108MES Periplasmic binding protein BaDB11_01845 ENOG4108V4B ThiJ pfpI BaDB11_01846 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) BaDB11_01847 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BaDB11_01848 ENOG4105CP7 Triose-phosphate isomerase BaDB11_01849 ENOG4105BZA Phosphoglycerate kinase BaDB11_01850 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BaDB11_01852 ENOG4105DEN Luciferase family BaDB11_01855 ENOG4105CIG ABC transporter BaDB11_01859 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BaDB11_01860 ENOG4105JXH GntR family transcriptional regulator BaDB11_01861 ENOG4105DAA L-lactate BaDB11_01862 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BaDB11_01864 ENOG4108ZPC Polysaccharide pyruvyl transferase BaDB11_01865 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BaDB11_01866 ENOG4105MME Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family BaDB11_01867 ENOG4105D3Q Sugar transferase BaDB11_01869 ENOG4105K64 Glycosyl transferase, family 2 BaDB11_01871 ENOG4107QRS glycosyltransferase group 2 family protein BaDB11_01872 ENOG41068W6 Capsular polysaccharide biosynthesis protein BaDB11_01873 ENOG4108KMV Glycosyl transferase (Group 1 BaDB11_01874 ENOG4105K64 Glycosyl transferase, family 2 BaDB11_01875 ENOG4108PQP glycosyl transferase group 1 BaDB11_01877 ENOG4108QV3 biosynthesis protein BaDB11_01878 ENOG4105HTX biosynthesis protein BaDB11_01880 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BaDB11_01881 ENOG4108I5G Major Facilitator superfamily BaDB11_01883 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) BaDB11_01884 ENOG4107S2N Type III effector Hrp-dependent BaDB11_01886 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BaDB11_01889 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BaDB11_01890 ENOG4105EDQ levansucrase EC 2.4.1.10 BaDB11_01891 ENOG4108HKT sucrose-6-phosphate hydrolase BaDB11_01894 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BaDB11_01897 ENOG4108URH decarboxylase BaDB11_01898 ENOG4105TPC MazG nucleotide pyrophosphohydrolase domain BaDB11_01899 ENOG4107TVP HD domain protein BaDB11_01900 ENOG4105CHH sulfate transporter BaDB11_01901 ENOG4108V2W Carbonate dehydratase BaDB11_01902 ENOG4105C5I Dehydrogenase BaDB11_01903 ENOG4108SQ9 flavin reductase domain protein, FMN-binding BaDB11_01904 ENOG4108ZHR arsR family transcriptional regulator BaDB11_01907 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BaDB11_01908 ENOG4105KRI phosphocarrier protein (HPr BaDB11_01909 ENOG4105CIE May be required for sporulation (By similarity) BaDB11_01910 ENOG4105CHW UPF0052 protein BaDB11_01911 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) BaDB11_01912 ENOG4108Z4K mutator MutT protein BaDB11_01913 ENOG4105C3M thioredoxin reductase BaDB11_01916 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase BaDB11_01917 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) BaDB11_01918 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase BaDB11_01919 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) BaDB11_01920 ENOG4105ECC imidazole-glycerol-phosphate dehydratase BaDB11_01921 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) BaDB11_01922 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) BaDB11_01923 ENOG4105C49 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity) BaDB11_01925 ENOG4108E16 pectate lyase BaDB11_01926 ENOG4108S4C acetyltransferase BaDB11_01927 ENOG4107XGZ Hydrolase BaDB11_01928 ENOG4105HKU nucleoside recognition domain-containing protein BaDB11_01930 ENOG4105D1C Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity) BaDB11_01931 ENOG410834F Transcriptional regulator BaDB11_01932 ENOG4105C0R drug resistance transporter emrb qaca subfamily BaDB11_01933 ENOG41088CQ domain protein BaDB11_01934 ENOG41086DT Membrane protein of unknown function BaDB11_01935 ENOG41067S9 phage shock protein C, PspC BaDB11_01936 ENOG4108PY7 BaDB11_01939 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BaDB11_01940 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) BaDB11_01945 ENOG4105CN1 protease BaDB11_01946 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BaDB11_01948 ENOG4105CRP Part of the ABC transporter FtsEX involved in BaDB11_01949 ENOG4105CAK Cell division ATP-binding protein ftsE BaDB11_01952 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) BaDB11_01953 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving BaDB11_01954 ENOG4105MS2 ribosomal subunit Interface protein BaDB11_01957 ENOG4105MQ3 flagellar protein FliS BaDB11_01958 ENOG4107RT6 flagellar hook-associated BaDB11_01959 ENOG41083S7 flagellar protein FlaG BaDB11_01960 ENOG4105I03 Flagellin BaDB11_01961 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) BaDB11_01962 ENOG4105W5T Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity) BaDB11_01963 ENOG4105MKD BaDB11_01964 ENOG4105DTJ flagellar hook-associated protein BaDB11_01965 ENOG4105E1Q flagellar hook-associated protein BaDB11_01968 ENOG4105RU3 BaDB11_01972 ENOG4105WH1 Two component transcriptional regulator luxr family BaDB11_01973 ENOG4105BZU Histidine kinase BaDB11_01974 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BaDB11_01975 ENOG4108KGH TRANSCRIPTIONal BaDB11_01977 ENOG4105ESV Glycosyl transferase, family 4 BaDB11_01978 ENOG4107EF8 Glycosyl transferase (Group 1 BaDB11_01981 ENOG4105QZI O-Antigen Polymerase BaDB11_01982 ENOG4105C1B dTDP-glucose 4-6-dehydratase BaDB11_01983 ENOG4105C6Y Udp-glucose 6-dehydrogenase BaDB11_01984 ENOG4107RA4 Glycosyl transferase (Group 1 BaDB11_01985 ENOG4105PSV Polysaccharide Biosynthesis Protein BaDB11_01986 ENOG4105D3Q Sugar transferase BaDB11_01987 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BaDB11_01988 ENOG4105JFG SpoIID LytB domain protein BaDB11_01990 ENOG4108KGH TRANSCRIPTIONal BaDB11_01991 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BaDB11_01992 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BaDB11_01993 ENOG4105EY8 ABC transporter BaDB11_01996 ENOG4107SJB teichoic acid biosynthesis BaDB11_01997 ENOG4107SJB teichoic acid biosynthesis BaDB11_01998 ENOG4107ZIC Glycerol-3-phosphate cytidylyltransferase BaDB11_02000 ENOG4107RZX Teichoic acid biosynthesis protein BaDB11_02002 ENOG4105DG6 mannose-6-phosphate isomerase BaDB11_02004 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BaDB11_02005 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) BaDB11_02006 ENOG4108UHU Aldolase BaDB11_02007 ENOG4105D7K pfkb domain protein BaDB11_02008 ENOG4108M60 Transcriptional regulator BaDB11_02010 ENOG4105CHR reductase BaDB11_02011 ENOG4105E2A Dehydrogenase BaDB11_02013 ENOG4105C54 Major Facilitator superfamily BaDB11_02014 ENOG4105C54 Major Facilitator superfamily BaDB11_02015 ENOG4108KGH TRANSCRIPTIONal BaDB11_02016 ENOG4105J7I hydrolase BaDB11_02017 ENOG4105K4H Nlp p60 protein BaDB11_02019 ENOG4105PNM synthesis protein BaDB11_02021 ENOG4105N98 Capsule biosynthesis protein capB BaDB11_02022 ENOG4105ETE Transcriptional regulator (LacI family BaDB11_02023 ENOG4108RVA ribokinase BaDB11_02024 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) BaDB11_02025 ENOG4105C2J ABC transporter BaDB11_02026 ENOG4105CNN ABC, transporter BaDB11_02027 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BaDB11_02028 ENOG4107FQX Alpha-acetolactate decarboxylase BaDB11_02030 ENOG4107RSM transcriptional regulator BaDB11_02031 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) BaDB11_02033 ENOG4105CAH Chromate BaDB11_02034 ENOG4105FGV Chromate BaDB11_02035 ENOG4108RB3 Capsular polysaccharide biosynthesis protein BaDB11_02036 ENOG4105HTX biosynthesis protein BaDB11_02038 ENOG4105KBK Zinc finger, swim domain protein BaDB11_02039 ENOG4105C0D helicase BaDB11_02041 ENOG410667J hydrolase BaDB11_02042 ENOG4105E98 transcriptional regulator DeoR family BaDB11_02044 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase BaDB11_02045 ENOG4105VI0 Pts system, glucitol sorbitol-specific BaDB11_02046 ENOG4105DZY Pts system, glucitol sorbitol-specific BaDB11_02047 ENOG410787A Pts system, glucitol sorbitol-specific BaDB11_02049 ENOG4105DKT Transcriptional regulator BaDB11_02050 ENOG4105Z8H single-stranded DNA-binding protein BaDB11_02054 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) BaDB11_02055 ENOG4105CGA flagellar basal-body rod protein FlgG BaDB11_02057 ENOG4105DFF Rod shape-determining protein mreb BaDB11_02058 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BaDB11_02059 ENOG4107MII Sugar-specific transcriptional regulator TrmB BaDB11_02060 ENOG4105CZM Major Facilitator BaDB11_02061 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BaDB11_02062 ENOG4105E2M Manganese-dependent inorganic pyrophosphatase BaDB11_02064 ENOG4108NA0 Uncharacterized conserved protein (COG2071) BaDB11_02065 ENOG41080XP Cbs domain BaDB11_02067 ENOG4105C37 (CBS) domain BaDB11_02068 ENOG4105BZU Histidine kinase BaDB11_02072 ENOG4105FRN stage II sporulation protein BaDB11_02073 ENOG4107TCE N-acetyltransferase BaDB11_02075 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BaDB11_02076 ENOG4105C0R drug resistance transporter emrb qaca subfamily BaDB11_02077 ENOG4105WQT MbtH domain protein BaDB11_02078 ENOG4105CEY Amp-dependent synthetase and ligase BaDB11_02079 ENOG4105WQI isochorismatase BaDB11_02080 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BaDB11_02081 ENOG4105E4F Isochorismate synthase BaDB11_02082 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BaDB11_02083 ENOG4105NIV Esterase BaDB11_02087 ENOG410874W AraC family transcriptional regulator BaDB11_02089 ENOG4108RYK Nad-dependent epimerase dehydratase BaDB11_02090 ENOG4108Z40 Transcriptional regulator BaDB11_02093 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BaDB11_02094 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BaDB11_02095 ENOG4105FCD Major Facilitator BaDB11_02096 ENOG4108HIZ formate dehydrogenase alpha subunit BaDB11_02097 ENOG4108TF4 von Willebrand factor, type A BaDB11_02100 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BaDB11_02102 ENOG4106778 Protein of unknown function (DUF1146) BaDB11_02103 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) BaDB11_02104 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) BaDB11_02105 ENOG4105J80 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity) BaDB11_02106 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) BaDB11_02107 ENOG4107YZM F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) BaDB11_02110 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) BaDB11_02112 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) BaDB11_02113 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) BaDB11_02114 ENOG4108UIC UPF0340 protein BaDB11_02115 ENOG4108YZG isomerase BaDB11_02116 ENOG4107WAU Protein tyrosine phosphatase BaDB11_02117 ENOG410815N Probably functions as a manganese efflux pump (By similarity) BaDB11_02118 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BaDB11_02120 ENOG4108ZXQ stage ii sporulation protein r BaDB11_02123 ENOG4105TRI Hydrolase BaDB11_02126 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BaDB11_02127 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BaDB11_02128 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BaDB11_02130 ENOG4107TT2 Auxin Efflux Carrier BaDB11_02131 ENOG4105C6K Malic enzyme BaDB11_02132 ENOG4107104 thymidine kinase BaDB11_02133 ENOG41082DI 50s ribosomal protein l31 BaDB11_02134 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BaDB11_02135 ENOG4105CBT Fructose-1,6-bisphosphatase BaDB11_02136 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BaDB11_02137 ENOG4107XMI Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway BaDB11_02138 ENOG4105D2N Aldolase BaDB11_02139 ENOG410812K response regulator receiver protein BaDB11_02141 ENOG4105DQ6 Transposase BaDB11_02144 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) BaDB11_02146 ENOG4105C1G acyl-Coa dehydrogenase BaDB11_02147 ENOG4105C1G acyl-Coa dehydrogenase BaDB11_02148 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BaDB11_02150 ENOG4105DF6 Fe-S oxidoreductase BaDB11_02154 ENOG4105C75 arginyL-tRNA synthetase BaDB11_02155 ENOG410684U Domain of unknown function (DUF1934) BaDB11_02156 ENOG4105CYW agmatinase BaDB11_02157 ENOG4105CCX Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BaDB11_02160 ENOG4105BZ4 penicillin-binding protein BaDB11_02161 ENOG4108XFG YwhD family BaDB11_02162 ENOG4108Z4T Peptidase M50 BaDB11_02163 ENOG41069HH 4-oxalocrotonate tautomerase BaDB11_02166 ENOG4105DCI Phosphohydrolase BaDB11_02168 ENOG4108VCI transcription factor, rsfa family BaDB11_02170 ENOG4105JGI Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity) BaDB11_02172 ENOG4105D2S major facilitator superfamily BaDB11_02177 ENOG4108FUF Transcriptional regulator, IclR family BaDB11_02179 ENOG4108IJ2 phosphate acetyltransferase BaDB11_02180 ENOG4107JTW chlorite dismutase BaDB11_02182 ENOG4105CZN Potassium uptake protein BaDB11_02186 ENOG4105CJ1 ABC, transporter BaDB11_02192 ENOG4105C26 Dehydrogenase BaDB11_02193 ENOG4105D5S Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity) BaDB11_02194 ENOG4108RJ9 Glycosyl transferase, family 2 BaDB11_02195 ENOG4105DWF phosphomethylpyrimidine kinase BaDB11_02198 ENOG4105C5Y PTS System BaDB11_02202 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BaDB11_02204 ENOG4105DEN Luciferase family BaDB11_02206 ENOG4108DBC nitroreductase BaDB11_02210 ENOG4105DWD nucleoside recognition domain protein BaDB11_02223 ENOG41060D1 Quinol oxidase BaDB11_02225 ENOG4105BZ9 Cytochrome C oxidase, subunit I BaDB11_02226 ENOG4105E2S oxidase) subunit II BaDB11_02227 ENOG4105CMR udp-glucose 4-epimerase BaDB11_02230 ENOG4108WS4 fmn reductase BaDB11_02233 ENOG4105CMG Carbohydrate kinase BaDB11_02234 ENOG4105C93 Xylose Isomerase BaDB11_02236 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) BaDB11_02237 ENOG4105C4U 4-methyl-5-beta-hydroxyethylthiazole kinase BaDB11_02238 ENOG4105CMU LysR family (Transcriptional regulator BaDB11_02242 ENOG41067MG lrgb family BaDB11_02244 ENOG4105CK7 Sodium proline symporter BaDB11_02245 ENOG4105DR4 Methyltransferase BaDB11_02247 ENOG4105C5I Dehydrogenase BaDB11_02248 ENOG4105X1N Glycosyl transferase family 8 BaDB11_02251 ENOG4105ENE Histidine kinase BaDB11_02252 ENOG4108VB1 regulatoR BaDB11_02253 ENOG4105EYF MMPL domain protein BaDB11_02255 ENOG4105DJB Major Facilitator Superfamily BaDB11_02256 ENOG4105CXK mandelate racemase muconate lactonizing BaDB11_02257 ENOG4108UHU Aldolase BaDB11_02258 ENOG4105D7K pfkb domain protein BaDB11_02260 ENOG4105IIU Aminopeptidase BaDB11_02261 ENOG41080V3 Major Facilitator superfamily BaDB11_02266 ENOG4108IQD Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity) BaDB11_02267 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BaDB11_02268 ENOG4105X96 Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity) BaDB11_02269 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BaDB11_02270 ENOG4105CM2 brancheD-chain amino acid aminotransferase BaDB11_02272 ENOG4105F8D glycoside hydrolase family 4 BaDB11_02273 ENOG4105VCP PTS System BaDB11_02274 ENOG4105CK1 PTS System BaDB11_02275 ENOG4105VZJ PTS System BaDB11_02276 ENOG4105EMD TRANSCRIPTIONal BaDB11_02278 ENOG4108VX5 3-methyladenine DNA glycosylase BaDB11_02281 ENOG4105DXD 2-methylcitrate dehydratase BaDB11_02282 ENOG4105CR4 methylisocitrate lyase BaDB11_02285 ENOG4105BZ1 (ABC) transporter BaDB11_02286 ENOG4107TDE lipolytic protein G-D-S-L family BaDB11_02289 ENOG4105C2C drug resistance transporter, Bcr CflA BaDB11_02291 ENOG4105DA5 (ABC) transporter BaDB11_02292 ENOG41069JR BaDB11_02297 ENOG4105CH6 catalase BaDB11_02299 ENOG4105G5W regulator Fur family BaDB11_02300 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BaDB11_02301 ENOG4108TU7 Inherit from COG: (ABC) transporter BaDB11_02302 ENOG4105CJ1 ABC, transporter BaDB11_02305 ENOG4105CJ1 ABC, transporter BaDB11_02315 ENOG4108J20 pectate lyase BaDB11_02316 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) BaDB11_02317 ENOG4108JJ8 (ABC) transporter BaDB11_02318 ENOG4108JJ9 ABC, transporter BaDB11_02319 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BaDB11_02320 ENOG4105C4M (Ubiquinol oxidase) subunit I BaDB11_02321 ENOG4108QTI )-transporter BaDB11_02324 ENOG4105DFD Na H antiporter BaDB11_02325 ENOG4108IJ0 Aspartate ammonia-lyase BaDB11_02326 ENOG4105HDK L-asparaginase BaDB11_02327 ENOG4108IMY Transcriptional regulator BaDB11_02328 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BaDB11_02336 ENOG4107BJW polysaccharide deacetylase BaDB11_02337 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BaDB11_02338 ENOG4107QZ7 Cellulose synthase catalytic subunit BaDB11_02339 ENOG4105D2K citrate carrier protein BaDB11_02340 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BaDB11_02341 ENOG4105X3H Excalibur domain protein BaDB11_02343 ENOG4105E0M Sulfatase BaDB11_02345 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BaDB11_02347 ENOG4105CEU Arginine dihydrolase BaDB11_02348 ENOG4105DBV ornithine carbamoyltransferase BaDB11_02350 ENOG4105C5B carbamate kinase BaDB11_02352 ENOG4105CS2 ec 3.2.1.21 BaDB11_02353 ENOG4105CK1 PTS System BaDB11_02355 ENOG4105JVQ RNA Polymerase BaDB11_02360 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BaDB11_02361 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BaDB11_02362 ENOG4107R3K hydrolase BaDB11_02363 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) BaDB11_02364 ENOG4105DRS transport system, permease BaDB11_02365 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BaDB11_02367 ENOG4105ETE Transcriptional regulator (LacI family BaDB11_02372 ENOG4105EDW glycosyl transferase, family 39 BaDB11_02373 ENOG4105CKK Glycosyl transferase, family 2 BaDB11_02374 ENOG4105CMR udp-glucose 4-epimerase BaDB11_02381 ENOG4105CH6 catalase BaDB11_02383 ENOG4105CS2 ec 3.2.1.21 BaDB11_02384 ENOG4105C5Y PTS System BaDB11_02385 ENOG4105CID antiterminator BaDB11_02386 ENOG4108W7F transporter, permease BaDB11_02387 ENOG4108JJB ABC transporter BaDB11_02388 ENOG4105NSK ABC superfamily ATP binding cassette transporter membrane protein BaDB11_02389 ENOG4105ETU transcriptional activator (TenA BaDB11_02392 ENOG4107QP3 malate synthase g BaDB11_02394 ENOG4105EDW glycosyl transferase, family 39 BaDB11_02396 ENOG4105C19 ABC transporter BaDB11_02397 ENOG4105EWM Histidine kinase BaDB11_02399 ENOG4105CS2 ec 3.2.1.21 BaDB11_02400 ENOG4105C5Y PTS System BaDB11_02402 ENOG4107QHE Choloylglycine hydrolase BaDB11_02403 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) BaDB11_02404 ENOG4106Z5D Glycoside Hydrolase Family 43 BaDB11_02405 ENOG4105C1J atp-dependent rna helicase BaDB11_02411 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BaDB11_02412 ENOG4105D9N nucleoside BaDB11_02413 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) BaDB11_02414 ENOG4107RHR regulatoR BaDB11_02418 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BaDB11_02419 ENOG4107R8N Glycosyl transferase, family 2 BaDB11_02421 ENOG4105JKW Valine--pyruvate aminotransferase BaDB11_02426 ENOG4105D2N Aldolase BaDB11_02427 ENOG4107TRN Xylose isomerase domain protein TIM barrel BaDB11_02428 ENOG4105F0H myo-inositol catabolism protein BaDB11_02429 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) BaDB11_02431 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) BaDB11_02432 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) BaDB11_02433 ENOG4105D7K pfkb domain protein BaDB11_02434 ENOG4105DH8 myo-inositol catabolism BaDB11_02435 ENOG4105C26 Dehydrogenase BaDB11_02437 ENOG4105CPC Aldo Keto reductase BaDB11_02438 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BaDB11_02439 ENOG4105CXY transporter BaDB11_02440 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) BaDB11_02441 ENOG4105C5H ABC transporter BaDB11_02442 ENOG410667J hydrolase BaDB11_02444 ENOG4105JAS Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity) BaDB11_02446 ENOG4108V5C ABC transporter BaDB11_02451 ENOG4105H93 Acyltransferase family BaDB11_02457 ENOG4105EC8 Methyl-accepting chemotaxis BaDB11_02458 ENOG4105BZG amino acid carrier protein BaDB11_02459 ENOG4105DCF alanine dehydrogenase BaDB11_02462 ENOG4105EG2 ABC transporter, permease BaDB11_02464 ENOG4107FKK extracellular solute-binding protein family 1 BaDB11_02466 ENOG4105CRD Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity) BaDB11_02467 ENOG4105CMR udp-glucose 4-epimerase BaDB11_02468 ENOG4105CKN UDP-glucose-hexose-1-phosphate uridylyltransferase BaDB11_02469 ENOG4105E2R ROK family BaDB11_02471 ENOG4105CMG Carbohydrate kinase BaDB11_02474 ENOG4108EKI Dehydrogenase BaDB11_02475 ENOG4105D3R alkyl hydroperoxide reductase BaDB11_02476 ENOG4108JU3 Alkyl hydroperoxide reductase BaDB11_02481 ENOG4108M15 ABC transporter BaDB11_02482 ENOG4105KCT ABC transporter BaDB11_02483 ENOG4105BZU Histidine kinase BaDB11_02490 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) BaDB11_02493 ENOG4105WQG acetyltransferase BaDB11_02496 ENOG4105C0H protease BaDB11_02497 ENOG4105Q2H domain protein BaDB11_02500 ENOG4105BZU Histidine kinase BaDB11_02501 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BaDB11_02507 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis BaDB11_02509 ENOG4105CDU Replicative dna helicase BaDB11_02513 ENOG4105DJ2 Major Facilitator Superfamily BaDB11_02514 ENOG4105CE4 GlcNAc 6-P deacetylase BaDB11_02515 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) BaDB11_02516 ENOG4105FDP GntR family transcriptional regulator BaDB11_02517 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate BaDB11_02519 ENOG4105K9Q Binds to the 23S rRNA (By similarity) BaDB11_02520 ENOG4105BZR domain protein BaDB11_02521 ENOG4108XMW Membrane BaDB11_02523 ENOG4107YZX Universal stress protein BaDB11_02524 ENOG4105CHH sulfate transporter BaDB11_02526 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) BaDB11_02527 ENOG4108UUM single-stranded DNA-binding protein BaDB11_02528 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) BaDB11_02529 ENOG4105C3G gtp-binding protein BaDB11_02530 ENOG4105VDK protein, conserved in bacteria BaDB11_02532 ENOG4108ZDA Sporulation protein YyaC BaDB11_02533 ENOG4105FA0 parb-like partition protein BaDB11_02534 ENOG4107QJE Chromosome Partitioning Protein BaDB11_02535 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) BaDB11_02537 ENOG410636K Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity) BaDB11_02539 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) BaDB11_02540 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) BaDB11_02543 ENOG4105M7T RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity) BaDB11_02544 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) BaDB11_02545 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BaDB11_02546 ENOG410848D S4 domain protein YaaA BaDB11_02547 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) BaDB11_02548 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BaDB11_02549 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BaDB11_02556 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BaDB11_02558 ENOG4105CD9 Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity) BaDB11_02559 ENOG4108UHX Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity) BaDB11_02560 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) BaDB11_02561 ENOG4105BZW Glycerate kinase BaDB11_02562 ENOG4107QQ0 gntp family BaDB11_02563 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR BaDB11_02566 ENOG4105ZMH deoxynucleoside kinase BaDB11_02568 ENOG4105VRS hydrolase family 18 BaDB11_02569 ENOG4105GTG Isochorismatase BaDB11_02570 ENOG4108Z6B deaminase BaDB11_02571 ENOG4105C6E dna polymerase iii BaDB11_02572 ENOG410816I Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) BaDB11_02573 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) BaDB11_02575 ENOG41067KS pro-sigma K processing BaDB11_02583 ENOG4105CDW Resistance protein BaDB11_02584 ENOG4105CXN decarboxylase BaDB11_02585 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) BaDB11_02586 ENOG4105X0R protein from nitrogen regulatory protein P-II BaDB11_02587 ENOG4105XVJ Protein of unknown function (DUF327) BaDB11_02588 ENOG4105FA2 dna polymerase iii BaDB11_02589 ENOG4105MA4 psp1 domain protein BaDB11_02590 ENOG4105QD5 Involved in initiation control of chromosome replication (By similarity) BaDB11_02591 ENOG41060K3 Methyltransferase BaDB11_02592 ENOG4105VC4 domain protein BaDB11_02593 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BaDB11_02594 ENOG4105KRN Transcriptional regulator, abrb family BaDB11_02595 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) BaDB11_02596 ENOG4105F8V Hydrolase, tatD family BaDB11_02597 ENOG41069ER domain protein BaDB11_02599 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) BaDB11_02600 ENOG4105XFA sporulation peptidase YabG BaDB11_02601 ENOG4105W42 Veg protein BaDB11_02602 ENOG4105XEW small acid-soluble spore protein BaDB11_02604 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) BaDB11_02605 ENOG4105DFT pur operon repressor BaDB11_02606 ENOG4105KME endoribonuclease L-psp BaDB11_02607 ENOG4105K4W Could be involved in septation (By similarity) BaDB11_02608 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) BaDB11_02609 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BaDB11_02610 ENOG4105KW6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) BaDB11_02613 ENOG4108JA2 transcriptioN-repair coupling factor BaDB11_02614 ENOG4108M14 stage v sporulation protein t BaDB11_02616 ENOG4108IY2 MazG family BaDB11_02617 ENOG41082I2 s4 domain protein BaDB11_02618 ENOG4105VYY sporulation protein yabp BaDB11_02621 ENOG41060GV RNA binding s1 domain protein BaDB11_02627 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BaDB11_02628 ENOG4108UGV hypoxanthine phosphoribosyltransferase BaDB11_02629 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BaDB11_02630 ENOG4105CGM Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity) BaDB11_02631 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) BaDB11_02632 ENOG4107U48 ppic-type peptidyL-prolyl cis-trans isomerase BaDB11_02633 ENOG4105C6T cysteine synthase BaDB11_02634 ENOG4105CRQ synthase (Component I) BaDB11_02635 ENOG4105DDQ anthranilate synthase BaDB11_02636 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 BaDB11_02637 ENOG4105EEI dihydropteroate synthase BaDB11_02638 ENOG4105KRF dihydroneopterin aldolase BaDB11_02639 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BaDB11_02641 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BaDB11_02642 ENOG4105CRK lysyL-tRNA synthetase BaDB11_02659 ENOG4108Z0C Uvrb UvrC protein BaDB11_02660 ENOG41066A3 ATP guanido phosphotransferase BaDB11_02662 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BaDB11_02663 ENOG4105E59 Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity) BaDB11_02664 ENOG4105CTP PilT protein domain protein BaDB11_02665 ENOG4108QHG Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) BaDB11_02666 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) BaDB11_02667 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) BaDB11_02668 ENOG4105D7W serine acetyltransferase BaDB11_02669 ENOG4105C8N cysteinyl-tRNA synthetase BaDB11_02670 ENOG4105KEB Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) BaDB11_02671 ENOG4105C2N RNA methyltransferase TrmH family group 3 BaDB11_02672 ENOG4105M0M Tetracycline resistance protein BaDB11_02673 ENOG4105QIV RNA polymerase BaDB11_02674 ENOG410683Z Preprotein translocase SecE subunit BaDB11_02675 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BaDB11_02676 ENOG4108UIK This protein binds directly to 23S ribosomal RNA (By similarity) BaDB11_02677 ENOG4105C64 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity) BaDB11_02678 ENOG4108VZM 50s ribosomal protein L10 BaDB11_02679 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) BaDB11_02680 ENOG4107Y49 methyltransferase BaDB11_02681 ENOG4108IIJ DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BaDB11_02682 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BaDB11_02683 ENOG4105XPM ribosomal protein BaDB11_02684 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) BaDB11_02685 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) BaDB11_02686 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) BaDB11_02687 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) BaDB11_02688 ENOG4108Z10 Involved in the binding of tRNA to the ribosomes (By similarity) BaDB11_02689 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) BaDB11_02690 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) BaDB11_02691 ENOG41080UE One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) BaDB11_02692 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity BaDB11_02693 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) BaDB11_02694 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) BaDB11_02695 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) BaDB11_02696 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) BaDB11_02697 ENOG41082SA 50s ribosomal protein l29 BaDB11_02698 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal BaDB11_02699 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) BaDB11_02700 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) BaDB11_02701 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits BaDB11_02702 ENOG41082QR Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) BaDB11_02703 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) BaDB11_02704 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BaDB11_02705 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) BaDB11_02706 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) BaDB11_02707 ENOG4105VPB 50S ribosomal protein L30 BaDB11_02708 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) BaDB11_02709 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BaDB11_02710 ENOG4105CC8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) BaDB11_02711 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BaDB11_02713 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) BaDB11_02715 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits BaDB11_02716 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) BaDB11_02717 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BaDB11_02718 ENOG4108ZT0 50S ribosomal protein l17 BaDB11_02719 ENOG4108JJB ABC transporter BaDB11_02720 ENOG4108JJB ABC transporter BaDB11_02721 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BaDB11_02722 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BaDB11_02723 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) BaDB11_02724 ENOG4108UJD 30S ribosomal protein S9 BaDB11_02728 ENOG4105D1F ATP-binding protein BaDB11_02731 ENOG4108NMV polysaccharide deacetylase BaDB11_02738 ENOG4108A04 Beta-lactamase BaDB11_02742 ENOG4105JAB phenazine biosynthesis protein, phzf family BaDB11_02743 ENOG4105EHZ conserved protein UCP016719 BaDB11_02744 ENOG4105D17 glycoside hydrolase, family 3 domain protein BaDB11_02748 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate BaDB11_02749 ENOG4105EWC Purine nucleoside phosphorylase BaDB11_02756 ENOG4105EMN RNA polymerase sigma factor BaDB11_02758 ENOG4105C8B TIGR00159 family BaDB11_02759 ENOG4107U5W ybbr family BaDB11_02760 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) BaDB11_02761 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BaDB11_02765 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BaDB11_02766 ENOG4105WAB arsR family transcriptional regulator BaDB11_02767 ENOG4108RWP Major Facilitator Superfamily protein BaDB11_02769 ENOG4105BZ1 (ABC) transporter BaDB11_02770 ENOG4107ZXU DSBA oxidoreductase BaDB11_02773 ENOG41075D4 Aminoglycoside 6-adenylyltransferase BaDB11_02779 ENOG4108MRH transcriptional regulatory protein BaDB11_02781 ENOG4105DUM transcriptional regulator, lysR family BaDB11_02783 ENOG4105E5W Transporter BaDB11_02784 ENOG4106DDH Sporulation-specific SASP protein BaDB11_02787 ENOG4105C7Z Conserved Protein BaDB11_02788 ENOG4105DXI Major Facilitator superfamily BaDB11_02793 ENOG4107I77 yiaA/B two helix domain BaDB11_02798 ENOG410631K Membrane BaDB11_02799 ENOG4106AXJ AraC family transcriptional regulator BaDB11_02803 ENOG4107SCQ Iron-containing alcohol dehydrogenase BaDB11_02804 ENOG4105C8Q Methyl-accepting chemotaxis BaDB11_02805 ENOG4105DFW ABC transporter BaDB11_02808 ENOG4105F9V Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid BaDB11_02810 ENOG4108IQI permease BaDB11_02811 ENOG4108J5H Homocysteine s-methyltransferase BaDB11_02813 ENOG4105CI1 PTS System BaDB11_02814 ENOG4107TXC Transcriptional regulator BaDB11_02815 ENOG4105H67 Protein of unknown function (DUF421) BaDB11_02819 ENOG4105CSV Glutaminase BaDB11_02822 ENOG4105KNA -acetyltransferase BaDB11_02824 ENOG4105NA0 Transcriptional regulator BaDB11_02826 ENOG4105DGI Alkaline phosphatase BaDB11_02827 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) BaDB11_02828 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BaDB11_02829 ENOG4105UVJ 5-dehydro-4-deoxyglucarate dehydratase BaDB11_02830 ENOG4105C26 Dehydrogenase BaDB11_02831 ENOG4105DJB Major Facilitator Superfamily BaDB11_02832 ENOG4105EQX glucarate dehydratase BaDB11_02833 ENOG41073TP transcriptional regulator BaDB11_02834 ENOG4105CTX dehydratase BaDB11_02835 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BaDB11_02836 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BaDB11_02841 ENOG4108R1P BaDB11_02842 ENOG4106K80 BaDB11_02844 ENOG41067TZ transcriptional regulator, MarR family BaDB11_02849 ENOG4107TXC Transcriptional regulator BaDB11_02854 ENOG4106UX7 integral membrane protein BaDB11_02856 ENOG41060AI SEC-C motif BaDB11_02857 ENOG4105DA5 (ABC) transporter BaDB11_02862 ENOG4108KSA LysR family transcriptional regulator BaDB11_02863 ENOG4105MDS 4-oxalocrotonate tautomerase BaDB11_02869 ENOG4108W0I acetyltransferase BaDB11_02871 ENOG4105DPN Oligoendopeptidase f BaDB11_02872 ENOG4107BMA Transglycosylase associated protein BaDB11_02874 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BaDB11_02875 ENOG4105CQB FAD linked oxidase domain protein BaDB11_02876 ENOG4105VZJ PTS System BaDB11_02877 ENOG4105VCP PTS System BaDB11_02878 ENOG4105CK1 PTS System BaDB11_02879 ENOG4105F8D glycoside hydrolase family 4 BaDB11_02880 ENOG4108X79 transcriptional regulator BaDB11_02881 ENOG410901P UPF0249 protein BaDB11_02884 ENOG4108CHM Preferentially cleaves peptide bonds on the carboxyl- terminal side of aspartate and glutamate. Along with other extracellular proteases it is involved in colonization and infection of human tissues. Required for proteolytic maturation of thiol protease SspB and inactivation of SspC, an inhibitor of SspB. It is the most important protease for degradation of fibronectin-binding protein (FnBP) and surface protein A, which are involved in adherence to host cells. May also protect bacteria against host defense mechanism by cleaving the immunoglobulin classes IgG, IgA and IgM. May be involved in the stability of secreted lipases BaDB11_02885 ENOG4105H9W Short-chain dehydrogenase reductase Sdr BaDB11_02888 ENOG4105KHC sulfurtransferase BaDB11_02890 ENOG4105DEN Luciferase family BaDB11_02891 ENOG4105Z8B NlpC/P60 family BaDB11_02893 ENOG4105CIG ABC transporter BaDB11_02894 ENOG4108RZE Tetr family transcriptional regulator BaDB11_02898 ENOG4108N0M stress protein BaDB11_02899 ENOG4106FN3 tellurium resistance protein BaDB11_02900 ENOG4106FN3 tellurium resistance protein BaDB11_02901 ENOG4107TS3 membrane protein, TerC BaDB11_02904 ENOG4108TTB tellurium resistance protein BaDB11_02906 ENOG4107QIV Cytochrome c biogenesis protein BaDB11_02908 ENOG4107SWG transcriptional regulator MERR family BaDB11_02915 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) BaDB11_02916 ENOG410756H nucleotidyltransferase BaDB11_02918 ENOG4105C26 Dehydrogenase BaDB11_02919 ENOG4105CK7 Sodium proline symporter BaDB11_02920 ENOG4107YHD transcriptional regulator BaDB11_02922 ENOG4108PJD permease BaDB11_02923 ENOG4105I82 acetyl xylan esterase BaDB11_02927 ENOG4105E5Q amino acid AbC transporter BaDB11_02928 ENOG4107XKZ Amino acid ABC superfamily ATP binding cassette transporter binding protein BaDB11_02929 ENOG4105NF4 modulator of drug activity BaDB11_02931 ENOG4105CS2 ec 3.2.1.21 BaDB11_02934 ENOG4107WDG serine threonine protein kinase BaDB11_02935 ENOG4105C8Q Methyl-accepting chemotaxis BaDB11_02941 ENOG4105F38 ABC transporter, permease BaDB11_02942 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component BaDB11_02943 ENOG4105CEY Amp-dependent synthetase and ligase BaDB11_02947 ENOG4105SX7 Transporter BaDB11_02949 ENOG4105W8Z 4'-phosphopantetheinyl transferase BaDB11_02950 ENOG4108SA1 esterase BaDB11_02954 ENOG4105CJ1 ABC, transporter BaDB11_02960 ENOG4105CDA abc transporter atp-binding protein BaDB11_02961 ENOG4105DRP amino acid AbC transporter BaDB11_02963 ENOG4108JUB Transcriptional regulator BaDB11_02964 ENOG4105C8Y Acetylornithine aminotransferase BaDB11_02965 ENOG4108IQI permease BaDB11_02966 ENOG41066UZ arginase EC 3.5.3.1 BaDB11_02967 ENOG4106P55 Transcriptional regulator BaDB11_02968 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase BaDB11_02969 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) BaDB11_02970 ENOG41069ZX BaDB11_02971 ENOG41069ZX BaDB11_02979 ENOG4107EV6 Inherit from COG: YD repeat protein BaDB11_02983 ENOG4105C2F Histidine kinase BaDB11_02984 ENOG4105WH1 Two component transcriptional regulator luxr family BaDB11_02985 ENOG4105DFW ABC transporter BaDB11_02987 ENOG4108HWW ABC transporter BaDB11_02988 ENOG4105DCM major facilitator superfamily BaDB11_02989 ENOG410645S MarR family Transcriptional regulator BaDB11_02990 ENOG4105C4C beta-galactosidase BaDB11_02991 ENOG4107T32 3-phytase (EC 3.1.3.8) BaDB11_02992 ENOG4105DUX Transporter BaDB11_02995 ENOG4105E1K spore germination protein BaDB11_02998 ENOG4107TXC Transcriptional regulator BaDB11_03000 ENOG4107WD8 ABC transporter, permease BaDB11_03001 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BaDB11_03002 ENOG4105BZU Histidine kinase BaDB11_03003 ENOG4105C8Q Methyl-accepting chemotaxis BaDB11_03005 ENOG4105CFH Aspartokinase BaDB11_03006 ENOG4105DHS permease protein BaDB11_03007 ENOG4105CM4 permease protein BaDB11_03008 ENOG4108IPW abc transporter atp-binding protein BaDB11_03011 ENOG4105R8C Transcriptional regulator BaDB11_03013 ENOG4108DBC nitroreductase BaDB11_03014 ENOG41067V3 Antibiotic biosynthesis monooxygenase BaDB11_03015 ENOG4105YVS arsR family transcriptional regulator BaDB11_03017 ENOG4108JPW Aminotransferase BaDB11_03018 ENOG4107QTZ amino acid BaDB11_03019 ENOG4105C26 Dehydrogenase BaDB11_03020 ENOG4108RNG Permease of the drug metabolite transporter BaDB11_03022 ENOG4105KTB nuclear export factor GLE1 BaDB11_03023 ENOG4108T5E Copper resistance protein BaDB11_03024 ENOG4108ZYE Transcriptional regulator BaDB11_03026 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BaDB11_03027 ENOG4108IFG nitrite reductase, (NAD(P)H) BaDB11_03028 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit BaDB11_03029 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BaDB11_03030 ENOG4105DRR Transcriptional regulator, GntR family BaDB11_03031 ENOG4105C8P )-transporter BaDB11_03033 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia BaDB11_03037 ENOG4108IUS Transketolase BaDB11_03039 ENOG4105E7W lamb ycsf family protein BaDB11_03040 ENOG4105C5A transporter BaDB11_03041 ENOG4105CFM UPF0317 protein BaDB11_03042 ENOG4105P4J Allophanate hydrolase, subunit 1 BaDB11_03044 ENOG4107258 Transcriptional regulator BaDB11_03045 ENOG4105XJB lipolytic protein G-D-S-L family BaDB11_03048 ENOG4107SQ3 mannitol-1-phosphate 5-dehydrogenase BaDB11_03049 ENOG4105ETD TRANSCRIPTIONal BaDB11_03050 ENOG4105CYX Short-chain dehydrogenase reductase Sdr BaDB11_03053 ENOG410606W general stress protein BaDB11_03055 ENOG4108RCF TRANSCRIPTIONal BaDB11_03056 ENOG4105VCH membrane BaDB11_03059 ENOG4105C9U ATP-dependent DNA helicase RecQ BaDB11_03060 ENOG4105C0X amino acid BaDB11_03061 ENOG4105DQ6 Transposase BaDB11_03064 ENOG4108M1A Chitin-binding protein BaDB11_03067 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BaDB11_03068 ENOG4107BMA Transglycosylase associated protein BaDB11_03069 ENOG4108IJ0 Aspartate ammonia-lyase BaDB11_03070 ENOG41087PP glycosyltransferase MGT family BaDB11_03071 ENOG4105NRR Uncharacterized protein conserved in bacteria (DUF2188) BaDB11_03072 ENOG4105EU9 BaDB11_03074 ENOG41082W1 Cupin 2, conserved barrel domain protein BaDB11_03075 ENOG4105QVS general stress protein BaDB11_03076 ENOG4106F5Q Membrane BaDB11_03077 ENOG4105CK2 sodium dicarboxylate symporter BaDB11_03078 ENOG4105CJ1 ABC, transporter BaDB11_03081 ENOG4105FDT acyl-CoA dehydrogenase BaDB11_03084 ENOG4105SZ6 Thioredoxin BaDB11_03085 ENOG4105CPF Cell wall formation (By similarity) BaDB11_03086 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BaDB11_03088 ENOG4105C1J atp-dependent rna helicase BaDB11_03089 ENOG410905X membrane-flanked domain protein BaDB11_03090 ENOG4105CKV Membrane BaDB11_03092 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein BaDB11_03093 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BaDB11_03095 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BaDB11_03096 ENOG4107MMM Anti-sigma-factor antagonist BaDB11_03097 ENOG4105FUA antagonist BaDB11_03098 ENOG4105QD0 anti-sigma regulatory factor serine threonine protein kinase BaDB11_03099 ENOG4107SGM protein serine threonine phosphatase BaDB11_03103 ENOG41064BQ Phosphatase BaDB11_03105 ENOG4105ST3 Transcriptional regulator BaDB11_03106 ENOG4105EYF MMPL domain protein BaDB11_03117 ENOG4105VZ8 Transcriptional regulator BaDB11_03118 ENOG4105ECK Fatty Acid Desaturase BaDB11_03119 ENOG4105VEQ Cold shock protein BaDB11_03120 ENOG4105CPQ Dehydrogenase BaDB11_03123 ENOG4108U05 Transcriptional regulator BaDB11_03124 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 BaDB11_03127 ENOG4105KVH Transcriptional regulator BaDB11_03133 ENOG4107XCH Cyclase family BaDB11_03134 ENOG4105C85 amino acid BaDB11_03137 ENOG4105JVQ RNA Polymerase BaDB11_03138 ENOG4108P49 AntiSigma factor BaDB11_03139 ENOG4105EXC Acyl-transferase BaDB11_03140 ENOG4105C2C drug resistance transporter, Bcr CflA BaDB11_03142 ENOG4108NEV two component transcriptional regulator, LytTR family BaDB11_03144 ENOG4108Z6X (sortase) family BaDB11_03145 ENOG4107QNK )-transporter BaDB11_03153 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) BaDB11_03154 ENOG4105K8N protein family UPF0079, ATPase BaDB11_03155 ENOG41072GX Peptidase M22 Glycoprotease BaDB11_03156 ENOG410801F ribosomal-protein-alanine acetyltransferase BaDB11_03157 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BaDB11_03158 ENOG4105C5H ABC transporter BaDB11_03160 ENOG4105FF6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity) BaDB11_03161 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) BaDB11_03162 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BaDB11_03164 ENOG4108TYN CAAX amino terminal protease family protein BaDB11_03165 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) BaDB11_03166 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) BaDB11_03172 ENOG41073R8 VanW family BaDB11_03175 ENOG4108RAV Conserved protein BaDB11_03176 ENOG4108X07 Tetr family transcriptional regulator BaDB11_03177 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BaDB11_03179 ENOG4105K78 MarR family Transcriptional regulator BaDB11_03180 ENOG4108VHC Short-chain dehydrogenase reductase Sdr BaDB11_03181 ENOG4105EBR Carboxylesterase BaDB11_03183 ENOG41087YS Phage shock protein A BaDB11_03184 ENOG4105DQX Zinc finger domain BaDB11_03185 ENOG4108WV1 Pfam:DUF477 BaDB11_03188 ENOG4108NGU Transcriptional regulator BaDB11_03189 ENOG4105N14 lysine exporter protein LysE YggA BaDB11_03191 ENOG4105CNI cell division protein FtsW BaDB11_03192 ENOG4105CNI cell division protein FtsW BaDB11_03196 ENOG4108ZJ4 polysaccharide deacetylase BaDB11_03197 ENOG4105E5K Alpha-amylase BaDB11_03198 ENOG4105FKQ transcriptional regulator BaDB11_03199 ENOG4108IUK alpha amylase, catalytic BaDB11_03200 ENOG4107FKK extracellular solute-binding protein family 1 BaDB11_03201 ENOG4105D56 permease protein BaDB11_03202 ENOG4105EG2 ABC transporter, permease BaDB11_03205 ENOG4105CG3 alpha amylase, catalytic region BaDB11_03206 ENOG4107URF beta-phospho-glucomutase BaDB11_03207 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BaDB11_03208 ENOG4105GVJ transcriptional regulator BaDB11_03220 ENOG4107STQ Multicopper oxidase BaDB11_03224 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BaDB11_03227 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BaDB11_03228 ENOG4105C7N Xanthine uracil vitamin C permease BaDB11_03231 ENOG4108U5N UPF0316 protein BaDB11_03233 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BaDB11_03234 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BaDB11_03235 ENOG4105C83 adenylosuccinate lyase BaDB11_03236 ENOG4105C8V SAICAR synthetase BaDB11_03237 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BaDB11_03239 ENOG4108JIU phosphoribosylformylglycinamidine synthase ii BaDB11_03241 ENOG4105CXB phosphoribosylaminoimidazole synthetase BaDB11_03242 ENOG4108V3E phosphoribosylglycinamide formyltransferase BaDB11_03243 ENOG4105DC1 bifunctional purine biosynthesis protein purh BaDB11_03244 ENOG4105C12 Phosphoribosylglycinamide synthetase BaDB11_03246 ENOG4106A3M Cytochrome p-450 BaDB11_03252 ENOG4108R5T secreted protein BaDB11_03253 ENOG4105KGF protein, YerC YecD BaDB11_03255 ENOG4105C4R Atp-dependent dna helicase BaDB11_03256 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) BaDB11_03258 ENOG4108M21 BaDB11_03260 ENOG4105MUZ Protein of unknown function DUF2620 BaDB11_03261 ENOG4106M0N transport system permease protein BaDB11_03262 ENOG41080QX K07048 phosphotriesterase-related protein BaDB11_03263 ENOG4106PKC pyridoxal phosphate binding BaDB11_03264 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) BaDB11_03265 ENOG4108626 Racemase BaDB11_03266 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) BaDB11_03267 ENOG4105KT7 mgtC SapB transporter BaDB11_03268 ENOG4105CK7 Sodium proline symporter BaDB11_03270 ENOG4105VB5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) BaDB11_03271 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BaDB11_03272 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) BaDB11_03275 ENOG4105D3P Mannan endo-1,4-beta-mannosidase BaDB11_03276 ENOG4108IG5 Transcriptional regulator BaDB11_03279 ENOG4105D9U N-acetyltransferase BaDB11_03280 ENOG4105DU0 nucleoside hydrolase BaDB11_03281 ENOG4105CBD Diacylglycerol kinase BaDB11_03282 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BaDB11_03284 ENOG4105C5Y PTS System BaDB11_03285 ENOG4105CS2 ec 3.2.1.21 BaDB11_03286 ENOG4105CID antiterminator BaDB11_03287 ENOG410780I phosphoprotein phosphatase activity BaDB11_03291 ENOG4105CDY transcriptional regulatory protein BaDB11_03294 ENOG4105C26 Dehydrogenase BaDB11_03295 ENOG4105FKZ Methyl-accepting chemotaxis BaDB11_03296 ENOG4105C8P )-transporter BaDB11_03297 ENOG4105C5H ABC transporter BaDB11_03299 ENOG4105DZA Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity) BaDB11_03300 ENOG4107T5J pyridine nucleotide-disulfide oxidoreductase BaDB11_03303 ENOG4105CKI cobalamin synthesis protein BaDB11_03304 ENOG4108W8G Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP (By similarity) BaDB11_03305 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BaDB11_03306 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BaDB11_03307 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) BaDB11_03308 ENOG4105CZF Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) BaDB11_03309 ENOG4106A3M Cytochrome p-450 BaDB11_03311 ENOG4107SWG transcriptional regulator MERR family BaDB11_03312 ENOG4105DXB Major Facilitator superfamily BaDB11_03313 ENOG4105C5H ABC transporter BaDB11_03314 ENOG4105FDU atp-dependent rna helicase BaDB11_03315 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein BaDB11_03318 ENOG4107QPK )-transporter BaDB11_03325 ENOG41082BM Transcriptional regulator, arsr family BaDB11_03326 ENOG410855V Acylphosphatase BaDB11_03327 ENOG4108RPX mosc domain containing protein BaDB11_03330 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BaDB11_03334 ENOG4105C5Y PTS System BaDB11_03335 ENOG4105CG3 alpha amylase, catalytic region BaDB11_03336 ENOG4107414 GntR family transcriptional regulator BaDB11_03341 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BaDB11_03342 ENOG4105D7W serine acetyltransferase BaDB11_03343 ENOG4108IAJ Nad-dependent epimerase dehydratase BaDB11_03346 ENOG4107TVC Glycosyl transferase, family 2 BaDB11_03349 ENOG4107QQG Dehydrogenase BaDB11_03351 ENOG4105KVH Transcriptional regulator BaDB11_03352 ENOG4108RCM Nitroreductase BaDB11_03353 ENOG4105CGH 5'-nucleotidase BaDB11_03354 ENOG4107RKG DJ-1/PfpI family BaDB11_03356 ENOG4105BZG amino acid carrier protein BaDB11_03357 ENOG4105KJF protein tyrosine phosphatase BaDB11_03359 ENOG4107U9T Pfam:Ribonuclease_BN BaDB11_03361 ENOG4108ISG Major Facilitator BaDB11_03363 ENOG4105UPD Calcium Proton BaDB11_03368 ENOG4105DCT glycerol dehydrogenase BaDB11_03370 ENOG4105D7N magnesium and cobalt transport protein CorA BaDB11_03372 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BaDB11_03379 ENOG41079KZ Major Facilitator Superfamily BaDB11_03383 ENOG4105EVH UPF0753 protein BaDB11_03384 ENOG4108TWJ NADH dehydrogenase subunit 5 BaDB11_03385 ENOG4105GPN Uncharacterized conserved protein (DUF2294) BaDB11_03387 ENOG4107RUY (E1 component), alpha subunit BaDB11_03389 ENOG4107QKR Dehydrogenase BaDB11_03391 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BaDB11_03392 ENOG4105KK4 UPF0060 membrane protein BaDB11_03393 ENOG4105F8D glycoside hydrolase family 4 BaDB11_03394 ENOG4108Q3X Transcriptional regulator BaDB11_03395 ENOG4105CI1 PTS System BaDB11_03398 ENOG4105KVH Transcriptional regulator BaDB11_03400 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BaDB11_03401 ENOG4105E4I Glycoside hydrolase family 28 BaDB11_03402 ENOG4105DSG hydrolase family 43 BaDB11_03403 ENOG4106HBX Transcriptional Regulator AraC Family BaDB11_03405 ENOG4105DYS nad(p)h dehydrogenase (quinone) BaDB11_03410 ENOG4105JAB phenazine biosynthesis protein, phzf family BaDB11_03411 ENOG4107Y03 Nitroreductase BaDB11_03415 ENOG4105ECP epimerase BaDB11_03416 ENOG410691R Modulates RecA activity (By similarity) BaDB11_03421 ENOG4105CKK Glycosyl transferase, family 2 BaDB11_03423 ENOG4105EJV Membrane BaDB11_03424 ENOG41067AE Membrane-bound metal-dependent hydrolase BaDB11_03425 ENOG4105CEN a g-specific adenine glycosylase BaDB11_03426 ENOG4106BXE BaDB11_03427 ENOG4105CAN Short-chain dehydrogenase reductase Sdr BaDB11_03431 ENOG4105BZ1 (ABC) transporter BaDB11_03432 ENOG4105C3U ABC transporter BaDB11_03433 ENOG4108JQ7 (ABC) transporter BaDB11_03434 ENOG4105DEF Extracellular solute-binding protein, family 5 BaDB11_03435 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BaDB11_03436 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BaDB11_03437 ENOG4107NBY Membrane BaDB11_03438 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase BaDB11_03439 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BaDB11_03440 ENOG4105G5W regulator Fur family BaDB11_03441 ENOG4105TUA UPF0295 protein BaDB11_03467 ENOG4107EV6 Inherit from COG: YD repeat protein BaDB11_03470 ENOG4107EV6 Inherit from COG: YD repeat protein BaDB11_03472 ENOG4105C22 threonyL-tRNA synthetase BaDB11_03473 ENOG4105FF2 Type I DHQase BaDB11_03474 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) BaDB11_03475 ENOG4105D7T ABC transporter BaDB11_03476 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein BaDB11_03477 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BaDB11_03478 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) BaDB11_03479 ENOG4107D63 BaDB11_03480 ENOG4105VZ8 Transcriptional regulator BaDB11_03482 ENOG4105DA5 (ABC) transporter BaDB11_03486 ENOG4105VBI Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) BaDB11_03489 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BaDB11_03491 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BaDB11_03495 ENOG4105CYN Serine protein kinase BaDB11_03496 ENOG4106AKX UPF0229 protein BaDB11_03497 ENOG4105DQ6 Transposase BaDB11_03499 ENOG4105CW7 secretion protein, HlyD family BaDB11_03500 ENOG4105C0R drug resistance transporter emrb qaca subfamily BaDB11_03501 ENOG4105CS1 NAD(P)H quinone oxidoreductase BaDB11_03503 ENOG4105CZV ABC transporter BaDB11_03504 ENOG4105CJ1 ABC, transporter BaDB11_03505 ENOG4108TU7 Inherit from COG: (ABC) transporter BaDB11_03506 ENOG4105VEQ Cold shock protein BaDB11_03507 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BaDB11_03508 ENOG4108UMI ABC transporter, permease BaDB11_03510 ENOG4107R6U sodium dicarboxylate symporter BaDB11_03516 ENOG4105BZU Histidine kinase BaDB11_03519 ENOG4108YBP pseudouridine synthase BaDB11_03521 ENOG41080XP Cbs domain BaDB11_03522 ENOG4107YBY Hydrolase BaDB11_03523 ENOG4105DGM nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BaDB11_03525 ENOG4105C5H ABC transporter BaDB11_03526 ENOG4105TMB Formate nitrite transporter BaDB11_03527 ENOG4105RK9 auxin efflux carrier BaDB11_03528 ENOG4105CB2 alcohol dehydrogenase BaDB11_03529 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BaDB11_03531 ENOG4108HMR Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) BaDB11_03532 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BaDB11_03536 ENOG4105BZU Histidine kinase BaDB11_03537 ENOG4105WH1 Two component transcriptional regulator luxr family BaDB11_03541 ENOG4105KPV Transcriptional regulator BaDB11_03542 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BaDB11_03543 ENOG4105ED1 spovr family BaDB11_03546 ENOG4105BZN citrate synthase BaDB11_03548 ENOG4105CYX Short-chain dehydrogenase reductase Sdr BaDB11_03549 ENOG4105C8J )-transporter BaDB11_03551 ENOG41086D8 Transcriptional regulator BaDB11_03552 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BaDB11_03555 ENOG4105J37 BaDB11_03556 ENOG4108AEY RNA polymerase sigma factor BaDB11_03557 ENOG4108VK3 Cupin 2 Conserved Barrel Domain Protein BaDB11_03559 ENOG4105F6E Acyl-transferase BaDB11_03561 ENOG4105KAF membrAne BaDB11_03564 ENOG4105U5Y Transcriptional regulator BaDB11_03565 ENOG4105C37 (CBS) domain BaDB11_03568 ENOG4105C37 (CBS) domain BaDB11_03574 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BaDB11_03576 ENOG4105D64 Mechanosensitive ion channel BaDB11_03577 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BaDB11_03579 ENOG4107VMI polysaccharide deacetylase BaDB11_03580 ENOG4105F0I Aminotransferase BaDB11_03582 ENOG4108N2V aldose 1-epimerase BaDB11_03587 ENOG4105BZ1 (ABC) transporter BaDB11_03588 ENOG4105BZ1 (ABC) transporter BaDB11_03596 ENOG410839P BaDB11_03598 ENOG4106MP8 UPF0754 membrane protein BaDB11_03599 ENOG4105WZB UPF0342 protein BaDB11_03601 ENOG4105D4P Coproporphyrinogen iii oxidase BaDB11_03602 ENOG4107S91 Sodium hydrogen exchanger BaDB11_03603 ENOG4105NCW Trka-c domain protein BaDB11_03605 ENOG4105CGU Enoyl-CoA hydratase BaDB11_03610 ENOG4108IUX (ABC) transporter BaDB11_03611 ENOG4105RHA ABC transporter, permease BaDB11_03612 ENOG4107VRP DNA repair exonuclease BaDB11_03613 ENOG4106D4I domain protein BaDB11_03614 ENOG4105EQI Metal Dependent Phosphohydrolase BaDB11_03616 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BaDB11_03623 ENOG4105NBU tryptophan transport protein BaDB11_03624 ENOG4105DXJ Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) BaDB11_03625 ENOG4105K59 histidine triad (HIT) protein BaDB11_03631 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BaDB11_03632 ENOG4105BZ4 penicillin-binding protein BaDB11_03633 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) BaDB11_03634 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BaDB11_03635 ENOG4105C1Q protoporphyrinogen oxidase BaDB11_03637 ENOG4105ECB domain protein BaDB11_03639 ENOG4105DER m42 family BaDB11_03642 ENOG4106AXD BaDB11_03643 ENOG4108RQ5 Beta-lactamase domain-containing protein BaDB11_03644 ENOG4105DF9 Lipoate-protein, ligase BaDB11_03645 ENOG4105CEY Amp-dependent synthetase and ligase BaDB11_03647 ENOG4108JCI Transcriptional regulator BaDB11_03650 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 BaDB11_03651 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin BaDB11_03652 ENOG4108UZ3 Transporter BaDB11_03653 ENOG4108HUF Transporter BaDB11_03654 ENOG4105DQ5 transport system permease protein BaDB11_03655 ENOG4108U1V ABC transporter, permease BaDB11_03656 ENOG4107TB6 phosphoglycerate mutase BaDB11_03657 ENOG4106YBV Methyl-accepting chemotaxis BaDB11_03661 ENOG4105XVF Competence transcription factor BaDB11_03662 ENOG41060YP BaDB11_03665 ENOG4105J8Z peptidase S8 and S53, subtilisin, kexin, sedolisin BaDB11_03667 ENOG4105G9B Transcriptional regulator BaDB11_03669 ENOG4107RNN dihydropyrimidinase (EC 3.5.2.2) BaDB11_03670 ENOG4105CE7 Amidase, hydantoinase carbamoylase family BaDB11_03671 ENOG4105S0E allantoin catabolism protein BaDB11_03672 ENOG4105DG4 malate L-lactate dehydrogenase BaDB11_03673 ENOG4105DG4 malate L-lactate dehydrogenase BaDB11_03674 ENOG4107R1Q Membrane protein FdrA BaDB11_03675 ENOG4107REC cytoplasmic protein BaDB11_03677 ENOG4105C5B carbamate kinase BaDB11_03678 ENOG4107SHS Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites (By similarity) BaDB11_03679 ENOG4107CUJ Protein of unknown function (DUF2690) BaDB11_03680 ENOG410780I phosphoprotein phosphatase activity BaDB11_03686 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component BaDB11_03687 ENOG4105I1K ABC transporter BaDB11_03689 ENOG4108KK1 membrane protein AbrB duplication BaDB11_03692 ENOG4105WEF catalase BaDB11_03693 ENOG4105CEY Amp-dependent synthetase and ligase BaDB11_03694 ENOG4106K7D Major facilitator family transporter BaDB11_03696 ENOG4105BZU Histidine kinase BaDB11_03697 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BaDB11_03699 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BaDB11_03700 ENOG4105E0C molybdate abc transporter BaDB11_03702 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation BaDB11_03704 ENOG4105EYH Exonuclease BaDB11_03711 ENOG410751J BaDB11_03715 ENOG4105ERH Fumarylacetoacetate hydrolase BaDB11_03721 ENOG4105CAQ asparagine synthetase BaDB11_03723 ENOG4108YZA Nitrogen regulatory protein pii BaDB11_03724 ENOG4105UQX Mate efflux family protein BaDB11_03725 ENOG4106HBX Transcriptional Regulator AraC Family BaDB11_03727 ENOG4105ETE Transcriptional regulator (LacI family BaDB11_03728 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) BaDB11_03729 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BaDB11_03731 ENOG4105DY8 decarboxylase BaDB11_03736 ENOG4105MA6 gCN5-related N-acetyltransferase BaDB11_03737 ENOG4105H9W Short-chain dehydrogenase reductase Sdr BaDB11_03738 ENOG4105D29 Helix-turn-helix type 11 domain protein BaDB11_03741 ENOG4108VPT UPF0234 protein BaDB11_03742 ENOG4105QNR S1 RNA binding domain protein BaDB11_03745 ENOG4105EPR degv family BaDB11_03746 ENOG4107AYK membrAne BaDB11_03748 ENOG4107SJ1 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity) BaDB11_03749 ENOG41073B9 BaDB11_03750 ENOG4108KP7 hydrolase BaDB11_03751 ENOG4108MXZ Esterase BaDB11_03752 ENOG4105VG1 fes assembly suf system protein BaDB11_03754 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase BaDB11_03755 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) BaDB11_03756 ENOG4105CAS nag kinase BaDB11_03757 ENOG4105C8Y Acetylornithine aminotransferase BaDB11_03758 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BaDB11_03760 ENOG4105DBV ornithine carbamoyltransferase BaDB11_03761 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BaDB11_03766 ENOG4107RMD Basic membrane lipoprotein BaDB11_03769 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BaDB11_03770 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BaDB11_03772 ENOG4105C3U ABC transporter BaDB11_03773 ENOG4108JQ7 (ABC) transporter BaDB11_03776 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BaDB11_03779 ENOG4105C31 Tryptophanyl-tRNA synthetase BaDB11_03780 ENOG4108J59 Extracellular solute-binding protein, family 5 BaDB11_03781 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BaDB11_03782 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BaDB11_03784 ENOG4108JQ7 (ABC) transporter BaDB11_03786 ENOG41090SU Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity) BaDB11_03787 ENOG4108ZCF integral membrane protein BaDB11_03788 ENOG4108SQ7 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis BaDB11_03792 ENOG4108V9W transcriptional regulatory protein BaDB11_03793 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BaDB11_03795 ENOG4105DPN Oligoendopeptidase f BaDB11_03797 ENOG4105T58 Dithiol-disulfide isomerase BaDB11_03798 ENOG4108Z18 K06886 hemoglobin BaDB11_03799 ENOG4105E4C Lytic transglycosylase catalytic BaDB11_03800 ENOG4105MIX Adenylate cyclase BaDB11_03801 ENOG4106EFP UPF0738 protein BaDB11_03803 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BaDB11_03804 ENOG4105EMS pseudouridine synthase BaDB11_03805 ENOG4107S1Q Phosphatase BaDB11_03807 ENOG4105ETU transcriptional activator (TenA BaDB11_03808 ENOG4108VEU Thiamine monophosphate synthase BaDB11_03811 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) BaDB11_03812 ENOG4105D06 uba thif-type nad fad binding protein BaDB11_03813 ENOG4105DWF phosphomethylpyrimidine kinase BaDB11_03814 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH BaDB11_03815 ENOG4107A88 BaDB11_03825 ENOG4105ENA helicase BaDB11_03827 ENOG4107T5V SNARE associated Golgi BaDB11_03828 ENOG4105CMR udp-glucose 4-epimerase BaDB11_03829 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BaDB11_03832 ENOG4108ZMI UPF0477 protein BaDB11_03836 ENOG4105C28 cystathionine BaDB11_03837 ENOG4105C28 cystathionine BaDB11_03838 ENOG4105JHY Membrane BaDB11_03841 ENOG4105FQP Beta-lactamase BaDB11_03842 ENOG4105FQP Beta-lactamase BaDB11_03843 ENOG4107PMW Arabinan endo-1,5-alpha-L-arabinosidase BaDB11_03846 ENOG4108UW5 maltose o-acetyltransferase BaDB11_03848 ENOG4105DUM transcriptional regulator, lysR family BaDB11_03849 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BaDB11_03850 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BaDB11_03852 ENOG4108Q5Y Membrane BaDB11_03853 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BaDB11_03855 ENOG41069ER domain protein BaDB11_03858 ENOG4105J7D transcriptional regulator BaDB11_03861 ENOG4107EV6 Inherit from COG: YD repeat protein BaDB11_03862 ENOG4105K7W phage-related replication protein BaDB11_03863 ENOG410635T phage-like element pbsx protein BaDB11_03873 ENOG4108TFU terminase (Small subunit) BaDB11_03874 ENOG4105IG6 Phage terminase, large subunit BaDB11_03875 ENOG4108MDF Phage Portal Protein BaDB11_03880 ENOG41060SN BaDB11_03883 ENOG4105PQS phage protein BaDB11_03884 ENOG4105FR7 XkdM protein, phage-like element PBSX BaDB11_03885 ENOG4105MTC XkdN-like protein BaDB11_03886 ENOG4108FKH Transglycosylase SLT domain BaDB11_03887 ENOG4108WZM domain protein BaDB11_03888 ENOG4105X7F BaDB11_03890 ENOG4105MFU Protein of unknown function (DUF2634) BaDB11_03891 ENOG41066EA baseplate J family protein BaDB11_03892 ENOG410906S phage-like element pbsx protein xkdt BaDB11_03894 ENOG41068G1 BaDB11_03895 ENOG41068G1 BaDB11_03898 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BaDB11_03899 ENOG4107XBN GntR Family Transcriptional Regulator BaDB11_03900 ENOG4105CPQ Dehydrogenase BaDB11_03901 ENOG4105CHZ Catalyzes the dehydration of D-mannonate (By similarity) BaDB11_03902 ENOG4105DMW Dehydrogenase reductase BaDB11_03903 ENOG4105CPQ Dehydrogenase BaDB11_03904 ENOG4108I5G Major Facilitator superfamily BaDB11_03907 ENOG4105CJ3 phosphate transporter BaDB11_03908 ENOG4107GRR phosphate transport regulator BaDB11_03909 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) BaDB11_03911 ENOG4105C2F Histidine kinase BaDB11_03912 ENOG4105EQD regulatoR BaDB11_03913 ENOG410769Z extracellular solute-binding protein family 1 BaDB11_03914 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BaDB11_03915 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component BaDB11_03916 ENOG4105F5H Glycosyl Hydrolase Family 88 BaDB11_03917 ENOG41075H3 AraC family transcriptional regulator BaDB11_03918 ENOG4107TDE lipolytic protein G-D-S-L family BaDB11_03921 ENOG4105CX8 fg-gap repeat protein BaDB11_03922 ENOG4107TDE lipolytic protein G-D-S-L family BaDB11_03923 ENOG4105CX8 fg-gap repeat protein BaDB11_03924 ENOG4105CPC Aldo Keto reductase BaDB11_03925 ENOG4107TDE lipolytic protein G-D-S-L family BaDB11_03927 ENOG4105EKC BaDB11_03928 ENOG4105E0S extracellular solute-binding protein family 1 BaDB11_03930 ENOG4105C50 Binding-protein-dependent transport systems, inner membrane component BaDB11_03931 ENOG4107R7I amino acid BaDB11_03934 ENOG4105C0H protease BaDB11_03936 ENOG4108ME1 Peptidase M55 D-aminopeptidase BaDB11_03937 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BaDB11_03938 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BaDB11_03939 ENOG4105C3U ABC transporter BaDB11_03941 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BaDB11_03942 ENOG4105DTQ mandelate racemase muconate lactonizing BaDB11_03943 ENOG4107SN7 NLP P60 protein BaDB11_03944 ENOG4108JQ7 (ABC) transporter BaDB11_03945 ENOG4107TUM Amidinotransferase BaDB11_03946 ENOG4107TUM Amidinotransferase BaDB11_03947 ENOG4108S4H thioesterase Superfamily protein BaDB11_03950 ENOG4108J20 pectate lyase BaDB11_03955 ENOG410839T multidrug resistance protein BaDB11_03956 ENOG41080TC multidrug resistance protein BaDB11_03957 ENOG4105CIY formyltetrahydrofolate deformylase BaDB11_03958 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) BaDB11_03959 ENOG4105C2S Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity) BaDB11_03961 ENOG4105K56 Transcriptional regulator BaDB11_03962 ENOG4108ZHJ Organic hydroperoxide resistance protein BaDB11_03964 ENOG4107Y2X deaminase BaDB11_03965 ENOG4105CVJ phosphoglycerate mutase BaDB11_03968 ENOG4107QYE Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) BaDB11_03969 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin BaDB11_03971 ENOG4105CJW magnesium transporter BaDB11_03973 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) BaDB11_03979 ENOG41067QW Transcriptional regulator BaDB11_03991 ENOG4108NF7 phage-type endonuclease BaDB11_03992 ENOG4108PNI recT protein BaDB11_04003 ENOG4105QBX endodeoxyribonuclease RusA BaDB11_04005 ENOG4108UUM single-stranded DNA-binding protein BaDB11_04016 ENOG4105IG6 Phage terminase, large subunit BaDB11_04040 ENOG4108VK3 Cupin 2 Conserved Barrel Domain Protein BaDB11_04042 ENOG4108QY0 Membrane BaDB11_04043 ENOG4105V75 Transcriptional regulator BaDB11_04047 ENOG4105DQE DNA ligase BaDB11_04048 ENOG4105FDF Could be involved in DNA repair (By similarity) BaDB11_04049 ENOG4105BZU Histidine kinase BaDB11_04050 ENOG4107T5V SNARE associated Golgi BaDB11_04051 ENOG4107TS3 membrane protein, TerC BaDB11_04052 ENOG4108WZW RNA polymerase sigma BaDB11_04054 ENOG410681C small acid-soluble spore protein BaDB11_04056 ENOG4105D0M Protease HtpX homolog BaDB11_04058 ENOG4107RVG penicillin-binding protein BaDB11_04061 ENOG4108TGC Acyltransferase BaDB11_04062 ENOG4105BZU Histidine kinase BaDB11_04063 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BaDB11_04065 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) BaDB11_04067 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BaDB11_04069 ENOG4105DT1 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate BaDB11_04071 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) BaDB11_04072 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) BaDB11_04075 ENOG4105BZU Histidine kinase BaDB11_04076 ENOG41090MY MarR family Transcriptional regulator BaDB11_04077 ENOG4105ER2 Ompa motb domain protein BaDB11_04078 ENOG4105E14 MotA TolQ exbB proton channel BaDB11_04080 ENOG4108K88 Membrane BaDB11_04081 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) BaDB11_04082 ENOG4107ZAE 6-carboxy-5,6,7,8-tetrahydropterin synthase BaDB11_04083 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BaDB11_04084 ENOG4105CSD Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity) BaDB11_04089 ENOG4105NX3 Membrane BaDB11_04090 ENOG4105VMP Transcriptional regulator BaDB11_04099 ENOG4105F0V Cell wall hydrolase BaDB11_04102 ENOG4105C59 p-type ATPase BaDB11_04103 ENOG4105DC7 peptidase M24 BaDB11_04107 ENOG4105CID antiterminator BaDB11_04109 ENOG4105KRI phosphocarrier protein (HPr BaDB11_04110 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BaDB11_04112 ENOG4105F6S Spore photoproduct lyase BaDB11_04114 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BaDB11_04115 ENOG4105CHR reductase BaDB11_04116 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BaDB11_04117 ENOG4105K4I Scp-like extracellular BaDB11_04119 ENOG4105BZU Histidine kinase BaDB11_04120 ENOG4105CHM Aminotransferase BaDB11_04124 ENOG4107R88 Chemotaxis protein (CheV) BaDB11_04125 ENOG4105UIN BaDB11_04127 ENOG4108QQZ ErfK YbiS YcfS YnhG family protein BaDB11_04129 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BaDB11_04130 ENOG4105EPM Diguanylate phosphodiesterase BaDB11_04132 ENOG4107IN1 Protein of unknown function (DUF1797) BaDB11_04134 ENOG4108XRC Protein of unknown function (DUF458) BaDB11_04140 ENOG4105NQC Flavodoxin BaDB11_04141 ENOG4105DMJ Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity) BaDB11_04144 ENOG4105D3R alkyl hydroperoxide reductase BaDB11_04145 ENOG4107R19 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BaDB11_04148 ENOG41082CS Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) BaDB11_04149 ENOG4105D06 uba thif-type nad fad binding protein BaDB11_04150 ENOG4105CVM Molybdenum cofactor synthesis domain protein BaDB11_04151 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BaDB11_04152 ENOG4108ZAF Molybdopterin BaDB11_04153 ENOG41067WU Molybdopterin converting factor (Subunit 1) BaDB11_04155 ENOG4105BZ1 (ABC) transporter BaDB11_04156 ENOG4105BZ1 (ABC) transporter BaDB11_04158 ENOG4107X8C Efflux transporter RND family MFP subunit BaDB11_04159 ENOG4105C19 ABC transporter BaDB11_04160 ENOG4107RBB ABC transporter, permease BaDB11_04161 ENOG4105E98 transcriptional regulator DeoR family BaDB11_04162 ENOG4105DE4 1-phosphofructokinase BaDB11_04163 ENOG4105DM4 PTS System BaDB11_04164 ENOG4105C3F Signal peptidase i BaDB11_04167 ENOG4105C5H ABC transporter BaDB11_04173 ENOG4105BZU Histidine kinase BaDB11_04174 ENOG4107ZYR domain protein BaDB11_04176 ENOG4105CN5 Metallo-Beta-Lactamase BaDB11_04178 ENOG4108X4Q Hydrolase BaDB11_04179 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BaDB11_04183 ENOG4105CPP Dehydrogenase, E1 component BaDB11_04184 ENOG4105C7S Dehydrogenase BaDB11_04185 ENOG4107QN2 dihydrolipoyl dehydrogenase BaDB11_04189 ENOG4105CXN decarboxylase BaDB11_04190 ENOG4105WBI UPF0223 protein BaDB11_04193 ENOG4105ECY inositol monophosphatase BaDB11_04199 ENOG4105CI3 gtp-binding protein typa BaDB11_04200 ENOG4105QA2 BaDB11_04202 ENOG4108INS Transcriptional regulator BaDB11_04203 ENOG4107SCK Monooxygenase BaDB11_04206 ENOG4108IAB Phoh family BaDB11_04208 ENOG4105CSV Glutaminase BaDB11_04209 ENOG4105ZPI UPF0358 protein BaDB11_04210 ENOG4105CNI cell division protein FtsW BaDB11_04211 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BaDB11_04213 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) BaDB11_04215 ENOG4105BZ9 Cytochrome C oxidase, subunit I BaDB11_04216 ENOG4105CCU oxidase (Subunit III) BaDB11_04217 ENOG41064X9 cytochrome C oxidase subunit IV BaDB11_04220 ENOG41080XQ Signal transduction protein with cbs domains BaDB11_04221 ENOG4106UY4 Inherit from COG: Scp-like extracellular BaDB11_04227 ENOG4106H78 methyltransferase BaDB11_04228 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) BaDB11_04229 ENOG4105H20 Sporulation integral membrane protein YlbJ BaDB11_04230 ENOG41063PX domain protein BaDB11_04231 ENOG4105CDE UPF0348 protein BaDB11_04232 ENOG4105KNH Nucleic acid-binding protein BaDB11_04233 ENOG41067VY 50S ribosomal protein L32 BaDB11_04237 ENOG41074B2 UPF0747 protein BaDB11_04238 ENOG4108V6E Cell division protein mraZ BaDB11_04239 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) BaDB11_04241 ENOG4105CJN penicillin-binding protein BaDB11_04242 ENOG4105CJN penicillin-binding protein BaDB11_04244 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BaDB11_04245 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) BaDB11_04246 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) BaDB11_04247 ENOG4105CNI cell division protein FtsW BaDB11_04248 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BaDB11_04249 ENOG4105D4A Cell wall formation (By similarity) BaDB11_04250 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) BaDB11_04251 ENOG4108R2U division initiation protein BaDB11_04253 ENOG4105K67 small basic protein BaDB11_04254 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BaDB11_04255 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BaDB11_04258 ENOG4105FFI sigma-e processing peptidase spoiiga BaDB11_04259 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BaDB11_04261 ENOG4105DKW ABC transporter BaDB11_04262 ENOG4105DHI Methyltransferase BaDB11_04263 ENOG4105WR5 sporulation protein, YlmC YmxH family BaDB11_04264 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BaDB11_04265 ENOG4105DFA alanine racemase domain protein BaDB11_04266 ENOG4105VR5 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity) BaDB11_04267 ENOG41067XK integral membrane protein BaDB11_04268 ENOG4105DBK s4 domain protein BaDB11_04272 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) BaDB11_04273 ENOG4105C34 Pseudouridine synthase BaDB11_04274 ENOG4108UK1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity) BaDB11_04276 ENOG4105CXT aspartate transcarbamylase BaDB11_04277 ENOG4105CD3 dihydroorotase BaDB11_04278 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BaDB11_04279 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain BaDB11_04280 ENOG4105DF0 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity) BaDB11_04281 ENOG4107RY0 Catalyzes the conversion of dihydroorotate to orotate (By similarity) BaDB11_04282 ENOG4106EG9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity) BaDB11_04285 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) BaDB11_04289 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BaDB11_04290 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BaDB11_04291 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BaDB11_04292 ENOG4105F23 Fibronectin-binding protein BaDB11_04294 ENOG4105DSJ YicC domain protein BaDB11_04295 ENOG4105KC4 UPF0296 protein BaDB11_04296 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) BaDB11_04297 ENOG4105ZAD Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) BaDB11_04298 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BaDB11_04299 ENOG4105C25 Primosomal protein n' BaDB11_04300 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BaDB11_04301 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) BaDB11_04302 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BaDB11_04303 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs BaDB11_04304 ENOG4108ZF3 Phosphatase BaDB11_04305 ENOG4105D9P serine threonine protein kinase BaDB11_04306 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) BaDB11_04307 ENOG4105DJV ribulose-phosphate 3-epimerase BaDB11_04308 ENOG4105FJ0 thiamine BaDB11_04309 ENOG4105VB9 50S ribosomal protein l28 BaDB11_04310 ENOG4108ZAA Alkaline-shock protein BaDB11_04311 ENOG4105DP4 dak2 domain fusion protein ylov BaDB11_04313 ENOG4105EJQ L-serine dehydratase BaDB11_04314 ENOG4105CB5 ATP-dependent DNA helicase recG BaDB11_04315 ENOG4108VVV Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity) BaDB11_04316 ENOG4105C6B Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity) BaDB11_04317 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BaDB11_04318 ENOG4105CHR reductase BaDB11_04319 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) BaDB11_04320 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) BaDB11_04321 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BaDB11_04322 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BaDB11_04323 ENOG4105VBN Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity) BaDB11_04325 ENOG4105K5M 30s ribosomal protein S16 BaDB11_04326 ENOG4108BW8 UPF0109 protein BaDB11_04328 ENOG4107Z8R An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) BaDB11_04329 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) BaDB11_04330 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) BaDB11_04331 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BaDB11_04332 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) BaDB11_04334 ENOG4105VM1 flagellar BaDB11_04335 ENOG4105CMV Succinyl-CoA synthetase subunit beta BaDB11_04336 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BaDB11_04337 ENOG4105C79 DNA protecting protein DprA BaDB11_04338 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BaDB11_04339 ENOG4107QXI Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity) BaDB11_04340 ENOG4108HE4 integrase family BaDB11_04341 ENOG4108R5P Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity) BaDB11_04342 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) BaDB11_04343 ENOG4105EUM DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (By similarity) BaDB11_04345 ENOG4105Q75 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BaDB11_04346 ENOG4108ZC9 flagellar basal-body rod protein flgc BaDB11_04347 ENOG4105VQ0 flagellar hook-basal body complex protein fliE BaDB11_04348 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) BaDB11_04349 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BaDB11_04352 ENOG4106YF4 Flagellar biosynthesis chaperone BaDB11_04354 ENOG410696Y Flagellar hook-length control protein BaDB11_04355 ENOG410822I Flagellar hook capping protein BaDB11_04356 ENOG4108JQA flagellar BaDB11_04358 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BaDB11_04359 ENOG4105DD5 Flagellar motor switch protein BaDB11_04360 ENOG4107YTP response regulator receiver protein BaDB11_04362 ENOG4105CN7 Flagellar biosynthetic protein FliP BaDB11_04363 ENOG4105VS8 Flagellar biosynthetic protein fliq BaDB11_04364 ENOG4105D19 Role in flagellar biosynthesis (By similarity) BaDB11_04365 ENOG4105D00 flagellar biosynthetic protein flhB BaDB11_04366 ENOG4105D7B Flagellar biosynthesis protein flha BaDB11_04367 ENOG4105FZW flagellar biosynthesis regulator FlhF BaDB11_04369 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) BaDB11_04370 ENOG4105CBS Chea signal transduction histidine kinase BaDB11_04371 ENOG410807Z Modulation of CheA activity in response to attractants (Chemotaxis BaDB11_04373 ENOG4108Z4W Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity) BaDB11_04374 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BaDB11_04376 ENOG4105CE9 30S ribosomal protein S2 BaDB11_04377 ENOG4105CU7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity) BaDB11_04379 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) BaDB11_04380 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BaDB11_04381 ENOG4105KNE Phosphatidate cytidylyltransferase BaDB11_04383 ENOG4105DZP Membrane-associated zinc metalloprotease BaDB11_04385 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BaDB11_04387 ENOG4105CYP glycoside hydrolase, family BaDB11_04390 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) BaDB11_04391 ENOG4105CHV Transcription elongation factor NusA BaDB11_04392 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BaDB11_04393 ENOG4105VHM ribosomal protein BaDB11_04394 ENOG4107EEM One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) BaDB11_04395 ENOG4105W7A Protein of unknown function (DUF503) BaDB11_04396 ENOG4105KG7 Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) BaDB11_04397 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) BaDB11_04398 ENOG4105DTN riboflavin biosynthesis protein ribF BaDB11_04399 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) BaDB11_04400 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) BaDB11_04402 ENOG4105C1V Peptidase, M16 BaDB11_04404 ENOG4105E35 Dipicolinate synthase subunit A BaDB11_04405 ENOG4108S0H Dipicolinic acid synthetase, b subunit BaDB11_04406 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BaDB11_04408 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BaDB11_04410 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit BaDB11_04412 ENOG4105CNU cell division protein FtsK BaDB11_04414 ENOG4105FDP GntR family transcriptional regulator BaDB11_04418 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BaDB11_04419 ENOG4105XZV Protein of unknown function (DUF3243) BaDB11_04422 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BaDB11_04423 ENOG4105CEV competence damage-inducible protein BaDB11_04424 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) BaDB11_04426 ENOG4105D48 metallophosphoesterase BaDB11_04427 ENOG4105MCT stage V sporulation protein S BaDB11_04428 ENOG4108IGT Dipeptidase BaDB11_04429 ENOG4105CPQ Dehydrogenase BaDB11_04430 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BaDB11_04431 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BaDB11_04434 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) BaDB11_04435 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) BaDB11_04437 ENOG4107EV6 Inherit from COG: YD repeat protein BaDB11_04440 ENOG4105CKI cobalamin synthesis protein BaDB11_04442 ENOG4107TCE N-acetyltransferase BaDB11_04446 ENOG4105XPP Protein of unknown function (DUF1275) BaDB11_04447 ENOG4105C3N Participates in control of cell volume in low-osmolarity conditions (By similarity) BaDB11_04448 ENOG4108J8C transporter major facilitator family protein BaDB11_04449 ENOG4108J8C transporter major facilitator family protein BaDB11_04450 ENOG4105U6C Alpha beta hydrolase fold protein BaDB11_04451 ENOG4105U6C Alpha beta hydrolase fold protein BaDB11_04453 ENOG41080BT SNARE associated Golgi BaDB11_04454 ENOG4105FQP Beta-lactamase BaDB11_04455 ENOG41087PP glycosyltransferase MGT family BaDB11_04456 ENOG4107QTZ amino acid BaDB11_04459 ENOG4105VRS hydrolase family 18 BaDB11_04460 ENOG4105M4P Tetr family transcriptional regulator BaDB11_04461 ENOG41062KD Inherit from COG: ketosteroid isomerase-like protein BaDB11_04462 ENOG4107S9F NmrA family BaDB11_04464 ENOG4108X3M OsmC Ohr family protein BaDB11_04465 ENOG4107E54 Small Multidrug Resistance protein BaDB11_04469 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) BaDB11_04470 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BaDB11_04472 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BaDB11_04473 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BaDB11_04474 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BaDB11_04475 ENOG4105U6W MutT NUDIX family protein BaDB11_04477 ENOG4108UNV SUF system FeS assembly protein, NifU family BaDB11_04478 ENOG4105G5W regulator Fur family BaDB11_04479 ENOG4105DRR Transcriptional regulator, GntR family BaDB11_04486 ENOG4105PF9 Transcriptional regulator