locus_tag old_locus_tag gene Name start end strand product note type ID NCBI S100027_00001 S100027_00001 S100027_00001 34 1341 + Chromosomal replication initiator protein DnaA ATP-binding%3B Cytoplasm%3B DNA replication%3B DNA-binding%3B Nucleotide-binding%3B Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replicatio%3B it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids%3B Belongs to the DnaA family gene gene0 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00001 S100027_00002 S100027_00002 dnaN dnaN 1518 2654 + DNA-directed DNA polymerase Cytoplasm%3B DNA replication%3B DNA-directed DNA polymerase%3B Nucleotidyltransferase%3B Transferase%3B KEGG: psj:PSJM300_00010 DNA polymerase III subunit beta gene gene1 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00002 S100027_00003 S100027_00003 S100027_00003 2822 3037 + uncharacterized protein RNA-binding%3B Contains 1 S4 RNA-binding domain gene gene2 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00003 S100027_00004 S100027_00004 S100027_00004 3054 4166 + DNA replication and repair protein RecF ATP-binding%3B Cytoplasm%3B DNA damage%3B DNA repair%3B DNA replication%3B DNA-binding%3B Nucleotide-binding%3B SOS response%3B The RecF protein is involved in DNA metabolis%3B it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded%2C linear DNA. It also seems to bind ATP%3B Belongs to the RecF family gene gene3 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00004 S100027_00005 S100027_00005 gyrB gyrB 4480 6399 + DNA topoisomerase (ATP-hydrolyzing) ATP-binding%3B DNA-binding%3B Isomerase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Topoisomerase%3B Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule%3B Belongs to the type II topoisomerase family. ParE type 2 subfamily%3B Contains 1 Toprim domain%3B KEGG: bli:BL00081 DNA gyrase subunit B gene gene4 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00005 S100027_00006 S100027_00006 gyrA gyrA 6590 9058 + DNA topoisomerase (ATP-hydrolyzing) ATP-binding%3B Cytoplasm%3B DNA-binding%3B Isomerase%3B Nucleotide-binding%3B Topoisomerase%3B DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings%2C including catenanes and knotted rings%3B Belongs to the topoisomerase GyrA/ParC subunit family%3B KEGG: bli:BL00082 DNA gyrase subunit A gene gene5 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00006 S100027_00007 S100027_00007 S100027_00007 9396 10945 + 16S ribosomal RNA rRNA gene6 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00007 S100027_00008 S100027_00008 S100027_00008 11048 11124 + tRNA-Ile tRNA gene7 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00008 S100027_00009 S100027_00009 S100027_00009 11136 11211 + tRNA-Ala tRNA gene8 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00009 S100027_00010 S100027_00010 S100027_00010 11282 14212 + 23S ribosomal RNA rRNA gene9 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00010 S100027_00011 S100027_00011 S100027_00011 14344 14459 + 5S ribosomal RNA rRNA gene10 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00011 S100027_00012 S100027_00012 S100027_00012 14475 15452 - uncharacterized protein gene gene11 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00012 S100027_00013 S100027_00013 guaB guaB 15574 17040 + IMP dehydrogenase CBS domain%3B GMP biosynthesis%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Potassium%3B Purine biosynthesis%3B Repeat%3B Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP)%2C the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides%2C and therefore plays an important role in the regulation of cell growth%3B Belongs to the IMPDH/GMPR family%3B Contains 2 CBS domains%3B KEGG: bsu:BSU00090 IMP dehydrogenase gene gene12 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00013 S100027_00014 S100027_00014 dacC dacC 17195 18520 + Serine-type D-Ala-D-Ala carboxypeptidase Carboxypeptidase%3B Cell shape%3B Cell wall%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Peptidoglycan synthesis%3B Protease%3B Secreted%3B Signal%3B Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. Belongs to the peptidase S11 family%3B KEGG: bss:BSUW23_00055 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6) gene gene13 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00014 S100027_00015 S100027_00015 pdxS pdxS 18707 19591 + Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) Lyase%3B Pyridoxal phosphate%3B Schiff base%3B Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP)%2C glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates%2C resulting from enzyme-catalyzed isomerization of RBP and G3P%2C respectively%3B Belongs to the PdxS/SNZ family%3B KEGG: bsu:BSU00110 pyridoxal 5'-phosphate synthase pdxS subunit gene gene14 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00015 S100027_00016 S100027_00016 pdxT pdxT 19613 20203 + Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) Glutamine amidotransferase%3B Hydrolase%3B Lyase%3B Pyridoxal phosphate%3B Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS%3B Belongs to the glutaminase PdxT/SNO family%3B KEGG: bsu:BSU00120 5'-phosphate synthase pdxT subunit gene gene15 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00016 S100027_00017 S100027_00017 sarS sarS 20531 21808 + Serine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine%2C to form the misacylated tRNA L-seryl-tRNA(Sec)%2C which will be further converted into selenocysteinyl-tRNA(Sec)%3B Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily%3B KEGG: dps:DP1764 seryl-tRNA synthetase gene gene16 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00017 S100027_00018 S100027_00018 glxK glxK 21838 22968 - Glycerate 3-kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the glycerate kinase type-1 family%3B KEGG: eco:b0514 glycerate kinase gene gene17 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00018 S100027_00019 S100027_00019 S100027_00019 22984 23568 - putative transporter Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the CitM (TC 2. A. 11) transporter family%3B overlaps another CDS with the same product name gene gene18 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00019 S100027_00020 S100027_00020 S100027_00020 23516 24250 - putative transporter Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the CitM (TC 2. A. 11) transporter family%3B overlaps another CDS with the same product name gene gene19 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00020 S100027_00021 S100027_00021 S100027_00021 24340 25458 - Carbohydrate diacid regulator Transcription%3B Transcription regulation%3B Seems to regulate the expression of the operons for the enzymes involved in D-galactarate%2C D-glucarate and D-glycerate utilization. Belongs to the CdaR family gene gene20 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00021 S100027_00022 S100027_00022 S100027_00022 25488 25910 - hypothetical protein gene gene21 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00022 S100027_00023 S100027_00023 S100027_00023 26040 26132 + tRNA-Ser tRNA gene22 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00023 S100027_00024 S100027_00024 S100027_00024 26266 26907 - Deoxyadenosine kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Plays an essential role in generating the deoxyribonucleotide precursors dATP AND dCTP for DNA metabolism. The phosphate acceptor specificity is strict toward deoxyadenosine (dAdo) and deoxycytidine (dCyd). The specificity toward the sugar moiety of the nucleoside is less strict. Both 2-deoxyribose%2C ribose%2C and arabinose nucleosides are phosphorylated%2C although the 2-deoxyribonucleosides are preferred. The phosphate donor specificity is dependent on the deoxyribonucleoside substrate%2C but GTP is efficient with both deoxycytidine and deoxyadenosine. Only nucleoside triphosphates can act as phosphate donors%3B Belongs to the DCK/DGK family%3B KEGG: bli:BL02366 deoxyadenosine/deoxycytidine kinase gene gene23 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00024 S100027_00025 S100027_00025 S100027_00025 26904 27527 - Deoxyguanosine kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as phosphate donor than CTP%2C ATP and GTP%3B Belongs to the DCK/DGK family%3B KEGG: bsu:BSU00150 deoxyguanosine kinase gene gene24 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00025 S100027_00026 S100027_00026 S100027_00026 27613 28932 - putative cell wall hydrolase LytN Cell wall biogenesis/degradation%3B Hydrolase%3B Secreted%3B Signal%3B Probably involved in peptidoglycan hydrolysis. Contains 1 LysM repeat%3B Contains 1 peptidase C51 domain gene gene25 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00026 S100027_00027 S100027_00027 entB entB 28970 29512 - Isochorismatase Hydrolase%3B Belongs to the isochorismatase family%3B KEGG: cko:CKO_02566 bifunctional isochorismate lyase / aryl carrier protein gene gene26 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00027 S100027_00028 S100027_00028 tadA tadA 29601 30083 + tRNA(adenine(34)) deaminase Hydrolase%3B Metal-binding%3B tRNA processing%3B Zinc%3B Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)%3B Belongs to the cytidine and deoxycytidylate deaminase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: eca:ECA3260 tRNA(adenine34) deaminase gene gene27 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00028 S100027_00029 S100027_00029 dnaX dnaX 30569 32269 + DNA-directed DNA polymerase ATP-binding%3B DNA replication%3B DNA-directed DNA polymerase%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase%3B DNA polymerase III is a complex%2C multichain enzyme responsible for most of the replicative synthesis in bacteria. Belongs to the DnaX/STICHEL family%3B KEGG: bsu:BSU00190 DNA polymerase III subunit gamma/tau gene gene28 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00029 S100027_00030 S100027_00030 S100027_00030 32296 32619 + Nucleoid-associated protein Cytoplasm%3B DNA-binding%3B Binds to DNA and alters its conformation. May be involved in regulation of gene expression%2C nucleoid organization and DNA protection%3B Belongs to the YbaB/EbfC family gene gene29 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00030 S100027_00031 S100027_00031 S100027_00031 32633 33229 + Recombination protein RecR DNA damage%3B DNA recombination%3B DNA repair%3B Metal-binding%3B Zinc%3B Zinc-finger%3B May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO%3B Belongs to the RecR family%3B Contains 1 Toprim domain gene gene30 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00031 S100027_00032 S100027_00032 S100027_00032 33250 33474 + uncharacterized protein gene gene31 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00032 S100027_00033 S100027_00033 S100027_00033 33488 33805 + Sigma-K factor-processing regulatory protein BofA Membrane%3B Metal-binding%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Zinc%3B Involved in the mediation of the intercompartmental coupling of pro-sigma K processing to events in the forespore. Inhibits SpoIVFB-processing activity until a signal has been received from the forespore. Could inhibit SpoIVFB metalloprotease activity by coordinating a zinc in the SpoIVFB active site%2C preventing access of a water molecule and the sequence of pro- sigma K%2C which are necessary for peptide bond hydrolysis to produce sigma-K gene gene32 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00033 S100027_00034 S100027_00034 S100027_00034 34092 35641 + 16S ribosomal RNA rRNA gene33 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00034 S100027_00035 S100027_00035 S100027_00035 35744 35820 + tRNA-Ile tRNA gene34 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00035 S100027_00036 S100027_00036 S100027_00036 35832 35907 + tRNA-Ala tRNA gene35 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00036 S100027_00037 S100027_00037 S100027_00037 35978 38908 + 23S ribosomal RNA rRNA gene36 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00037 S100027_00038 S100027_00038 S100027_00038 39041 39156 + 5S ribosomal RNA rRNA gene37 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00038 S100027_00039 S100027_00039 S100027_00039 39325 39516 + Protein CsfB gene gene38 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00039 S100027_00040 S100027_00040 S100027_00040 39709 40326 + Protein XpaC Hydrolase. gene gene39 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00040 S100027_00041 S100027_00041 S100027_00041 40342 41535 + uncharacterized protein Belongs to the TelA family gene gene40 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00041 S100027_00042 S100027_00042 ldcC ldcC 41676 43118 + Lysine decarboxylase Decarboxylase%3B Lyase%3B Pyridoxal phosphate%3B Belongs to the Orn/Lys/Arg decarboxylase class-I family%3B KEGG: bca:BCE_0027 lysine decarboxylase gene gene41 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00042 S100027_00043 S100027_00043 S100027_00043 43115 43753 + dTMP kinase ATP-binding%3B Kinase%3B Nucleotide biosynthesis%3B Nucleotide-binding%3B Transferase%3B Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis%3B Belongs to the thymidylate kinase family%3B KEGG: pol:Bpro_2519 dTMP kinase gene gene42 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00043 S100027_00044 S100027_00044 S100027_00044 43829 44158 + uncharacterized protein gene gene43 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00044 S100027_00045 S100027_00045 S100027_00045 44170 44610 + uncharacterized protein gene gene44 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00045 S100027_00046 S100027_00046 holB holB 44622 45611 + DNA-directed DNA polymerase DNA replication%3B DNA-directed DNA polymerase%3B Nucleotidyltransferase%3B Transferase%3B KEGG: bli:BL00541 DNA polymerase III subunit delta' gene gene45 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00046 S100027_00047 S100027_00047 S100027_00047 45614 46441 + Stage 0 sporulation protein YaaT Cytoplasm%3B Sporulation%3B Essential for the phosphorelay during initiation of sporulation. May control the level of phosphorylated spo0A through spo0E activity during sporulation%3B Contains 1 PSP1 C-terminal domain gene gene46 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00047 S100027_00048 S100027_00048 S100027_00048 46456 46818 + Initiation-control protein YabA DNA replication%3B Involved in initiation control of chromosome replication%3B Belongs to the YabA family gene gene47 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00048 S100027_00049 S100027_00049 S100027_00049 46883 47626 + uncharacterized protein gene gene48 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00049 S100027_00050 S100027_00050 S100027_00050 47613 47906 + UPF0213 protein Belongs to the UPF0213 family%3B Contains 1 GIY-YIG domain gene gene49 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00050 S100027_00051 S100027_00051 rsmI rsmI 47878 48756 + 16S rRNA (cytidine(1402)-2'-O)-methyltransferase Cytoplasm%3B Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA%3B Belongs to the methyltransferase superfamily. RsmI family%3B KEGG: bli:BL00535 16S rRNA (cytidine1402-2'-O)-methyltransferase gene gene50 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00051 S100027_00052 S100027_00052 S100027_00052 48805 49089 - Transition state regulatory protein AbrB Activator%3B DNA-binding%3B Repressor%3B Sporulation%3B Transcription%3B Transcription regulation%3B Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites%2C it may be the sole repressor of tycA transcription%3B Contains 1 SpoVT-AbrB domain%3B To B. subtilis Abh and SpoVT gene gene51 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00052 S100027_00053 S100027_00053 marS marS 49603 51591 + Methionine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B RNA-binding%3B tRNA-binding%3B Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation%3B Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily%3B Contains 1 tRNA-binding domain%3B KEGG: bli:BL00533 methionyl-tRNA synthetase gene gene52 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00053 S100027_00054 S100027_00054 tatD tatD 51676 52443 + putative metal-dependent hydrolase YabD Hydrolase%3B Metal-binding%3B Belongs to the TatD-type hydrolase family%3B KEGG: bsu:BSU00390 TatD DNase family protein%3B Endodeoxyribonucleases producing 5'-phosphomonoesters gene gene53 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00054 S100027_00055 S100027_00055 S100027_00055 52473 53885 + uncharacterized protein Contains 1 G5 domain gene gene54 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00055 S100027_00056 S100027_00056 rnmV rnmV 54053 54613 + Ribonuclease M5 Cytoplasm%3B Endonuclease%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nuclease%3B Ribosome biogenesis%3B RNA-binding%3B rRNA processing%3B rRNA-binding%3B Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step%3B Belongs to the ribonuclease M5 family%3B Contains 1 Toprim domain%3B KEGG: bsu:BSU00410 ribonuclease M5 gene gene55 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00056 S100027_00057 S100027_00057 ksgA ksgA 54606 55484 + 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase Cytoplasm%3B Methyltransferase%3B RNA-binding%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily%3B KEGG: bsu:BSU00420 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase gene gene56 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00057 S100027_00058 S100027_00058 S100027_00058 55643 56524 + Sporulation-specific protease YabG Hydrolase%3B Membrane%3B Sporulation%3B Cleaves the spore coat proteins SpoIVA and SafA. May cooperate with tgl to mediate the temperature-dependent cross- linking of coat proteins like GerQ%3B Belongs to the peptidase U57 family gene gene57 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00058 S100027_00059 S100027_00059 S100027_00059 56749 57009 + Protein Veg Cytoplasm%3B Sporulation%3B Stimulates biofilm formation via transcriptional activation of extracellular matrix genes. Acts by repressing SinR activity%2C independently of the SinI%2C SlrA and SlrR pathways. Could also be involved in the regulation of other genes during biofilm and spore formation gene gene58 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00059 S100027_00060 S100027_00060 S100027_00060 57166 57351 + Protein SspF DNA-binding%3B Sporulation%3B May play some important role in either sporulation or the dormant spore. Belongs to the alpha/beta-type SASP family gene gene59 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00060 S100027_00061 S100027_00061 S100027_00061 57406 57576 - hypothetical protein gene gene60 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00061 S100027_00062 S100027_00062 ispE ispE 57649 58518 + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase ATP-binding%3B Isoprene biosynthesis%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol%3B Belongs to the GHMP kinase family. IspE subfamily%3B KEGG: rhl:LPU83_0984 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase gene gene61 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00062 S100027_00063 S100027_00063 S100027_00063 58575 59408 + Pur operon repressor DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Controls the transcription of the pur operon for purine biosynthetic genes%2C binds to the control region of the operon. DNA binding is inhibited by 5-phosphoribosyl 1-pyrophosphate. Belongs to the purine/pyrimidine phosphoribosyltransferase family gene gene62 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00063 S100027_00064 S100027_00064 ridA ridA 59426 59803 + 2-iminobutanoate/2-iminopropanoate deaminase Belongs to the RutC family%3B KEGG: bcib:IM45_599 2-iminobutanoate/2-iminopropanoate deaminase gene gene63 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00064 S100027_00065 S100027_00065 S100027_00065 59983 60276 + Putative septation protein SpoVG Cell cycle%3B Cell division%3B Septation%3B Could be involved in septation%3B Belongs to the SpoVG family gene gene64 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00065 S100027_00066 S100027_00066 glmU glmU 60581 61951 + UDP-N-acetylglucosamine diphosphorylase Acyltransferase%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Magnesium%3B Metal-binding%3B Multifunctional enzyme%3B Nucleotidyltransferase%3B Peptidoglycan synthesis%3B Repeat%3B Transferase%3B Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P)%2C which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate)%2C a reaction catalyzed by the N-terminal domain%3B In the N-terminal sectio%3B belongs to the N- acetylglucosamine-1-phosphate uridyltransferase family%3B In the C-terminal sectio%3B belongs to the transferase hexapeptide repeat family%3B KEGG: bsu:BSU00500 bifunctional UDP-N-acetylglucosamine pyrophosphorylase / Glucosamine-1-phosphate N-acetyltransferase gene gene65 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00066 S100027_00067 S100027_00067 prpS prpS 61972 62922 + Ribose-phosphate diphosphokinase ATP-binding%3B Cytoplasm%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide biosynthesis%3B Nucleotide-binding%3B Transferase%3B Involved in the biosynthesis of ribose 1%2C5-bisphosphate. Catalyzes the transfer of pyrophosphoryl group from ATP to ribose- 5-phosphate to yield phosphoribosyl diphosphate (PRPP) and AMP%3B Belongs to the ribose-phosphate pyrophosphokinase family%3B KEGG: bli:BL00519 ribose-phosphate pyrophosphokinase gene gene66 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00067 S100027_00068 S100027_00068 S100027_00068 63003 63629 + 50S ribosomal protein L25 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance%3B Belongs to the ribosomal protein L25P family. CTC subfamily gene gene67 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00068 S100027_00069 S100027_00069 pth1 pth1 63746 64312 + Aminoacyl-tRNA hydrolase Cytoplasm%3B Hydrolase%3B The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis%3B Belongs to the PTH family%3B KEGG: mlo:mlr2694 peptidyl-tRNA hydrolase%2C PTH1 family gene gene68 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00069 S100027_00070 S100027_00070 S100027_00070 64369 64599 + uncharacterized protein gene gene69 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00070 S100027_00071 S100027_00071 S100027_00071 64664 68197 + Transcription-repair-coupling factor ATP-binding%3B Cytoplasm%3B DNA damage%3B DNA repair%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA%2C and recruitment of nucleotide excision repair machinery to the damaged site%3B In the N-terminal sectio%3B belongs to the UvrB family%3B In the C-terminal sectio%3B belongs to the helicase family. RecG subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bsu:BSU00550 transcription-repair coupling factor (superfamily II helicase)%3B Acting on ATP%3B involved in cellular and subcellular movement gene gene70 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00071 S100027_00072 S100027_00072 S100027_00072 68335 68871 + Stage V sporulation protein Activator%3B DNA-binding%3B Repressor%3B Sporulation%3B Transcription%3B Transcription regulation%3B Positive and negative transcriptional regulator of sigma G-dependent genes. May provide a mechanism of feedback control that is important for forespore development%3B Contains 1 SpoVT-AbrB domain%3B To B. subtilis AbrB and Abh gene gene71 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00072 S100027_00073 S100027_00073 S100027_00073 69085 70677 + putative membrane protein YabM Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the polysaccharide synthase family gene gene72 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00073 S100027_00074 S100027_00074 S100027_00074 70667 72136 + uncharacterized protein gene gene73 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00074 S100027_00075 S100027_00075 S100027_00075 72143 72406 + uncharacterized protein RNA-binding%3B Contains 1 S4 RNA-binding domain gene gene74 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00075 S100027_00076 S100027_00076 S100027_00076 72483 72791 + Spore protein YabP Membrane%3B Sporulation%3B Required for sporulation gene gene75 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00076 S100027_00077 S100027_00077 S100027_00077 72788 73414 + Spore protein YabQ Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Required for sporulation. Plays an important role in cortex and coat formation gene gene76 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00077 S100027_00078 S100027_00078 S100027_00078 73431 73808 + Cell division protein DivIC gene gene77 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00078 S100027_00079 S100027_00079 S100027_00079 73888 74286 + uncharacterized protein Belongs to the peptidase U57 family%3B Contains 1 S1 motif domain gene gene78 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00079 S100027_00080 S100027_00080 S100027_00080 74437 74510 + tRNA-Met tRNA gene79 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00080 S100027_00081 S100027_00081 S100027_00081 74521 74592 + tRNA-Glu tRNA gene80 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00081 S100027_00082 S100027_00082 S100027_00082 74802 77291 + Protein-serine/threonine phosphatase Cell membrane%3B Hydrolase%3B Membrane%3B Protein phosphatase%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Normally needed for pro-sigma E processing during sporulation but can be bypassed in vegetative cells. Activates SpoIIAA by dephosphorylation. Contains 1 PPM-type phosphatase domain%3B KEGG: bsu:BSU00640 stage II sporulation protein E gene gene81 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00082 S100027_00083 S100027_00083 S100027_00083 77368 78105 + uncharacterized protein gene gene82 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00083 S100027_00084 S100027_00084 S100027_00084 78074 79108 + Non-specific serine/threonine protein kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Serine/threonine-protein kinase%3B Transferase%3B Belongs to the protein kinase superfamily. Ser/Thr protein kinase family%3B Contains 1 protein kinase domain%3B KEGG: bli:BL00504 serine/threonine protein kinase%2C bacterial gene gene83 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00084 S100027_00085 S100027_00085 tilS tilS 79211 80641 + tRNA(Ile)-lysidine synthetase ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B tRNA processing%3B Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU%2C in an ATP-dependent manner. Cytidine is converted to lysidine%2C thus changing the amino acid specificity of the tRNA from methionine to isoleucine%3B Belongs to the tRNA(Ile)-lysidine synthase family%3B KEGG: bli:BL00503 tRNA(Ile)-lysidine synthase gene gene84 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00085 S100027_00086 S100027_00086 hprT hprT 80625 81164 + Hypoxanthine phosphoribosyltransferase Cytoplasm%3B Glycosyltransferase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Purine salvage%3B Transferase%3B Belongs to the purine/pyrimidine phosphoribosyltransferase family%3B KEGG: bli:BL05003 hypoxanthine phosphoribosyltransferase gene gene85 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00086 S100027_00087 S100027_00087 ftsH ftsH 81261 83180 + ATP-dependent zinc metalloprotease FtsH ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Metal-binding%3B Metalloprotease%3B Nucleotide-binding%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Zinc%3B Acts as a processive%2C ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins%3B In the central sectio%3B belongs to the AAA ATPase family%3B In the C-terminal sectio%3B belongs to the peptidase M41 family%3B KEGG: bsu:BSU00690 cell division protease FtsH%3B Metalloendopeptidases gene gene86 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00087 S100027_00088 S100027_00088 coaX coaX 83383 84159 + Pantothenate kinase ATP-binding%3B Coenzyme A biosynthesis%3B Cytoplasm%3B Kinase%3B Metal-binding%3B Nucleotide-binding%3B Potassium%3B Transferase%3B Catalyzes the phosphorylation of pantothenate (Pan)%2C the first step in CoA biosynthesis%3B Belongs to the type III pantothenate kinase family%3B KEGG: gsu:GSU1934 type III pantothenate kinase gene gene87 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00088 S100027_00089 S100027_00089 S100027_00089 84171 85040 + 33 kDa chaperonin Chaperone%3B Cytoplasm%3B Disulfide bond%3B Redox-active center%3B Zinc%3B Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress%3B Belongs to the HSP33 family gene gene88 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00089 S100027_00090 S100027_00090 prsA prsA 85093 85983 + Peptidylprolyl isomerase Isomerase%3B Rotamase%3B Signal%3B Contains 1 PpiC domain%3B KEGG: baci:B1NLA3E_00340 foldase protein PrsA gene gene89 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00090 S100027_00091 S100027_00091 cysK cysK 86059 86982 + Cysteine synthase Amino-acid biosynthesis%3B Cysteine biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Catalyzes the conversion of O-acetylserine to cysteine. Also acts as a sensor of cysteine availability in the signal transduction pathway modulating CymR activity. When cysteine is present%2C the pool of O-acetylserine (OAS) is low%2C which leads to the formation of a CymR-CysK complex and transcriptional repression of the CymR regulon occurs. In the absence of cysteine%2C the OAS pool is high and the CymR-CysK complex is mostly dissociated%2C leading to a faster dissociation of CymR from its DNA targets and the lifting of CymR-dependent repression%3B Belongs to the cysteine synthase/cystathionine beta- synthase family%3B KEGG: bsu:BSU00730 cysteine synthase A gene gene90 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00091 S100027_00092 S100027_00092 pabB pabB 87179 88612 + Aminodeoxychorismate synthase Folate biosynthesis%3B Magnesium%3B Transferase%3B Part of a heterodimeric complex that catalyzes the two- step biosynthesis of 4-amino-4-deoxychorismate (ADC)%2C a precursor of p-aminobenzoate (PABA) and tetrahydrofolate. In the first step%2C a glutamine amidotransferase (PabA) generates ammonia as a substrate that%2C along with chorismate%2C is used in the second step%2C catalyzed by aminodeoxychorismate synthase (PabB) to produce ADC%3B Belongs to the anthranilate synthase component I family%3B KEGG: bld:BLi00090 para-aminobenzoate synthetase component I%3B overlaps another CDS with the same product name gene gene91 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00092 S100027_00093 S100027_00093 pabA pabA 88609 89193 + Aminodeoxychorismate synthase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Folate biosynthesis%3B Glutamine amidotransferase%3B Lyase%3B Transferase%3B Tryptophan biosynthesis%3B Part of a heterodimeric complex that catalyzes the two- step biosynthesis of 4-amino-4-deoxychorismate (ADC)%2C a precursor of p-aminobenzoate (PABA) and tetrahydrofolate. In the first step%2C a glutamine amidotransferase (PabA) generates ammonia as a substrate that%2C along with chorismate%2C is used in the second step%2C catalyzed by aminodeoxychorismate synthase (PabB) to produce ADC. PabA converts glutamine into glutamate only in the presence of stoichiometric amounts of PabB. Also involved in the biosynthesis of anthranilate%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: eco:b3360 para-aminobenzoate synthetase component II%3B overlaps another CDS with the same product name gene gene92 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00093 S100027_00094 S100027_00094 ilvE ilvE 89190 90050 + Branched-chain-amino-acid transaminase Amino-acid biosynthesis%3B Aminotransferase%3B Branched-chain amino acid biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Acts on leucine%2C isoleucine and valine%3B Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: eca:ECA2971 branched-chain amino acid aminotransferase gene gene93 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00094 S100027_00095 S100027_00095 folP folP 90063 90920 + Dihydropteroate synthase Folate biosynthesis%3B Magnesium%3B Metal-binding%3B Transferase%3B Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7%2C8-dihydropterin diphosphate (DHPt-PP) to form 7%2C8-dihydropteroate (H2Pte)%2C the immediate precursor of folate derivatives%3B Belongs to the DHPS family%3B Contains 1 pterin-binding domain%3B KEGG: bli:BL00861 dihydropteroate synthase gene gene94 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00095 S100027_00096 S100027_00096 folB folB 90892 91275 + Dihydroneopterin aldolase Folate biosynthesis%3B Lyase%3B Catalyzes the conversion of 7%2C8-dihydroneopterin to 6- hydroxymethyl-7%2C8-dihydropterin%3B Belongs to the DHNA family%3B KEGG: bli:BL00862 dihydroneopterin aldolase gene gene95 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00096 S100027_00097 S100027_00097 folK folK 91272 91772 + 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase ATP-binding%3B Folate biosynthesis%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the HPPK family%3B KEGG: bli:BL05004 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase gene gene96 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00097 S100027_00098 S100027_00098 S100027_00098 91724 91933 + putative HTH-type transcriptional regulator YazB DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene97 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00098 S100027_00099 S100027_00099 dusB dusB 91950 92951 + putative tRNA-dihydrouridine synthase Flavoprotein%3B FMN%3B NADP%3B Oxidoreductase%3B RNA-binding%3B tRNA processing%3B tRNA-binding%3B Catalyzes the synthesis of 5%2C6-dihydrouridine (D)%2C a modified base found in the D-loop of most tRNAs%2C via the reduction of the C5-C6 double bond in target uridines%3B Belongs to the Dus family%3B KEGG: rpo:MA1_00045 tRNA-dihydrouridine synthase B%3B Oxidoreductases gene gene98 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00099 S100027_00100 S100027_00100 karS karS 93033 94535 + Lysine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: blh:BaLi_c00980 lysyl-tRNA synthetase%2C class II gene gene99 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00100 S100027_00101 S100027_00101 S100027_00101 94833 96382 + 16S ribosomal RNA rRNA gene100 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00101 S100027_00102 S100027_00102 S100027_00102 96557 99487 + 23S ribosomal RNA rRNA gene101 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00102 S100027_00103 S100027_00103 S100027_00103 99620 99735 + 5S ribosomal RNA rRNA gene102 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00103 S100027_00104 S100027_00104 S100027_00104 99756 99831 + tRNA-Val tRNA gene103 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00104 S100027_00105 S100027_00105 S100027_00105 99853 99928 + tRNA-Thr tRNA gene104 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00105 S100027_00106 S100027_00106 S100027_00106 99964 100039 + tRNA-Lys tRNA gene105 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00106 S100027_00107 S100027_00107 S100027_00107 100046 100128 + tRNA-Leu tRNA gene106 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00107 S100027_00108 S100027_00108 S100027_00108 100145 100219 + tRNA-Gly tRNA gene107 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00108 S100027_00109 S100027_00109 S100027_00109 100229 100314 + tRNA-Leu tRNA gene108 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00109 S100027_00110 S100027_00110 S100027_00110 100324 100400 + tRNA-Arg tRNA gene109 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00110 S100027_00111 S100027_00111 S100027_00111 100411 100487 + tRNA-Pro tRNA gene110 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00111 S100027_00112 S100027_00112 S100027_00112 100494 100569 + tRNA-Ala tRNA gene111 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00112 S100027_00113 S100027_00113 S100027_00113 100726 102275 + 16S ribosomal RNA rRNA gene112 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00113 S100027_00114 S100027_00114 S100027_00114 102450 105380 + 23S ribosomal RNA rRNA gene113 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00114 S100027_00115 S100027_00115 S100027_00115 105513 105628 + 5S ribosomal RNA rRNA gene114 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00115 S100027_00116 S100027_00116 S100027_00116 105805 106269 + Transcriptional regulator CtsR DNA-binding%3B Phosphoprotein%3B Repressor%3B Stress response%3B Transcription%3B Transcription regulation%3B Controls the expression of the cellular protein quality control genes clpC%2C clpE and clpP%2C as well as mcsA and mcsB. Acts as a repressor of these class III stress genes by binding to a directly repeated heptanucleotide operator sequence (A/GGTCAAA NAN A/GGTCAAA). After heat shock%2C CtsR is degraded by the ClpCP and ClpEP proteolytic systems%2C ensuring the derepression of clpE%2C clpP and the clpC operon. CtsR negatively autoregulates its own synthesis%3B Belongs to the CtsR family gene gene115 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00116 S100027_00117 S100027_00117 S100027_00117 106407 106838 + Protein-arginine kinase activator protein Phosphoprotein%3B Activates the phosphorylation activity of the protein- arginine kinase McsB. Is required for the delocalization of competence proteins from the cell poles%3B Contains 1 UVR domain gene gene116 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00117 S100027_00118 S100027_00118 mcsB mcsB 106838 107929 + Protein arginine kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes%2C such as protein homeostasis%2C motility%2C competence%2C and stringent and stress responses%2C by regulating gene expression and protein activity%3B Belongs to the ATP:guanido phosphotransferase family%3B Contains 1 phosphagen kinase C-terminal domain%3B KEGG: bli:BL03260 protein arginine kinase gene gene117 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00118 S100027_00119 S100027_00119 S100027_00119 107926 110358 + Chaperone protein ClpB ATP-binding%3B Chaperone%3B Coiled coil%3B Cytoplasm%3B Nucleotide-binding%3B Repeat%3B Stress response%3B Part of a stress-induced multi-chaperone system%2C it is involved in the recovery of the cell from heat-induced damage%2C in cooperation with DnaK%2C DnaJ and GrpE. Acts before DnaK%2C in the processing of protein aggregates. Protein binding stimulates the ATPase activit%3B ATP hydrolysis unfolds the denatured protein aggregates%2C which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates%2C contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity)%3B Belongs to the ClpA/ClpB family%3B Contains 1 UVR domain gene gene118 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00119 S100027_00120 S100027_00120 S100027_00120 110438 111817 + DNA repair protein RadA like protein ATP-binding%3B DNA damage%3B DNA repair%3B DNA-binding%3B Metal-binding%3B Nucleotide-binding%3B Zinc%3B Zinc-finger%3B May play a role in the repair of endogenous alkylation damage%3B Belongs to the RecA family. RadA subfamily gene gene119 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00120 S100027_00121 S100027_00121 disA disA 111821 112897 + Diadenylate cyclase ATP-binding%3B DNA damage%3B DNA repair%3B DNA-binding%3B Magnesium%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase%3B Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation%2C searching for lesions. When a lesion is present%2C DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation%3B Has also diadenylate cyclase activity%2C catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome%2C operates as a positive signal that advances sporulatio%3B upon encountering a lesion%2C the DisA focus arrests at the damaged site and halts c-di- AMP synthesis%3B Belongs to the DisA family%3B KEGG: bli:BL03263 diadenylate cyclase gene gene120 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00121 S100027_00122 S100027_00122 S100027_00122 113029 114117 + putative PIN and TRAM-domain containing protein YacL Hydrolase%3B Magnesium%3B Metal-binding%3B Nuclease%3B An RNase%3B Belongs to the ycf81 family%3B In the central sectio%3B belongs to the PINc/VapC protein family%3B Contains 1 PINc domain%3B Contains 1 TRAM domain gene gene121 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00122 S100027_00123 S100027_00123 ispD ispD 114134 114829 + 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Isoprene biosynthesis%3B Nucleotidyltransferase%3B Transferase%3B Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)%3B Belongs to the IspD family%3B KEGG: bsu:BSU00900 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase gene gene122 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00123 S100027_00124 S100027_00124 ispF ispF 114822 115298 + 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate synthase Isoprene biosynthesis%3B Lyase%3B Metal-binding%3B Multifunctional enzyme%3B Nucleotidyltransferase%3B Transferase%3B Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD)%2C and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2%2C4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)%3B In the N-terminal sectio%3B belongs to the IspD family%3B In the C-terminal sectio%3B belongs to the IspF family%3B KEGG: ctu:CTU_33200 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate synthase gene gene123 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00124 S100027_00125 S100027_00125 gltX gltX 115380 116837 + Glutamate--tRNA(Gln) ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)%3B Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: bsu:BSU00920 nondiscriminating glutamyl-tRNA synthetase gene gene124 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00125 S100027_00126 S100027_00126 cysE cysE 117139 117789 + Serine O-acetyltransferase Acyltransferase%3B Amino-acid biosynthesis%3B Cysteine biosynthesis%3B Cytoplasm%3B Repeat%3B Transferase%3B Catalyzes the acetylation of serine by acetyl-CoA to produce O-acetylserine (OAS)%3B Belongs to the transferase hexapeptide repeat family%3B KEGG: cha:CHAB381_0927 serine O-acetyltransferase gene gene125 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00126 S100027_00127 S100027_00127 carS carS 117786 119189 + Cysteine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B Zinc%3B Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: fau:Fraau_2118 cysteinyl-tRNA synthetase gene gene126 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00127 S100027_00128 S100027_00128 S100027_00128 119192 119608 + Mini-ribonuclease Cytoplasm%3B Endonuclease%3B Hydrolase%3B Magnesium%3B Nuclease%3B Ribosome biogenesis%3B RNA-binding%3B rRNA processing%3B rRNA-binding%3B Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc%3B Rnc processes 30S rRNA into smaller rRNA precursors. Cleaves more efficiently on assembled 50S ribosomal subunits. Cleavage is strongly stimulated by ribosomal protein L3 (RplC%3B 20-30%25 DMSO can replace RplC%2C suggesting RplC may alter rRNA conformation%3B Belongs to the MrnC RNase family%3B KEGG: bli:BL03270 ribonuclease III family protein%3B Endoribonucleases producing 5'-phosphomonoesters gene gene127 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00128 S100027_00129 S100027_00129 rlmB rlmB 119605 120354 + 23S rRNA (guanosine(2251)-2'-O)-methyltransferase Methyltransferase%3B Transferase%3B Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family%3B KEGG: bsu:BSU00960 23S rRNA (guanosine2251-2'-O)-methyltransferase gene gene128 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00129 S100027_00130 S100027_00130 S100027_00130 120360 120872 + uncharacterized protein gene gene129 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00130 S100027_00131 S100027_00131 S100027_00131 120936 121607 + RNA polymerase sigma-H factor DNA-binding%3B Sigma factor%3B Sporulation%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in the transition to post-exponential phase in the beginning of sporulation. Belongs to the sigma-70 factor family gene gene130 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00131 S100027_00132 S100027_00132 S100027_00132 121875 122054 + Protein translocase subunit SecE Cell membrane%3B Membrane%3B Protein transport%3B Translocation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation%3B Belongs to the SecE/SEC61-gamma family gene gene131 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00132 S100027_00133 S100027_00133 S100027_00133 122226 122765 + Transcription termination/antitermination protein NusG Transcription%3B Transcription antitermination%3B Transcription regulation%3B Transcription termination%3B Participates in transcription elongation%2C termination and antitermination. In the absence of Rho%2C increases the rate of transcription elongation by the RNA polymerase (RNAP)%2C probably by partially suppressing pausing. In the presence of Rho%2C modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination%3B Belongs to the NusG family%3B Contains 1 KOW domain gene gene132 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00133 S100027_00134 S100027_00134 S100027_00134 122935 123360 + 50S ribosomal protein L11-1 Methylation%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors%3B Belongs to the ribosomal protein L11P family gene gene133 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00134 S100027_00135 S100027_00135 S100027_00135 123462 124160 + 50S ribosomal protein L1 Repressor%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Translation regulation%3B tRNA-binding%3B Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome%2C and is involved in E site tRNA release%3B Protein L1 is also a translational repressor protein%2C it controls the translation of the L11 operon by binding to its mRNA%3B Belongs to the ribosomal protein L1P family gene gene134 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00135 S100027_00136 S100027_00136 S100027_00136 124422 124922 + 50S ribosomal protein L10 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Forms part of the ribosomal stalk%2C playing a central role in the interaction of the ribosome with GTP-bound translation factors%3B Belongs to the ribosomal protein L10P family gene gene135 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00136 S100027_00137 S100027_00137 S100027_00137 124967 125338 + 50S ribosomal protein L7/L12 Ribonucleoprotein%3B Ribosomal protein%3B Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation%3B Belongs to the ribosomal protein L7/L12P family gene gene136 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00137 S100027_00138 S100027_00138 rsmC rsmC 125478 126083 + 16S rRNA (guanine(1207)-N(2))-methyltransferase Methyltransferase%3B Transferase%3B Belongs to the methyltransferase superfamily%3B KEGG: bsu:BSU01060 16S rRNA (guanine1207-N2)-methyltransferase gene gene137 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00138 S100027_00139 S100027_00139 rpoB rpoB 126334 129915 + DNA-directed RNA polymerase DNA-directed RNA polymerase%3B Nucleotidyltransferase%3B Transcription%3B Transferase%3B DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B Belongs to the RNA polymerase beta chain family%3B KEGG: bsu:BSU01070 DNA-directed RNA polymerase subunit beta gene gene138 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00139 S100027_00140 S100027_00140 rpoC rpoC 129975 133574 + DNA-directed RNA polymerase DNA-directed RNA polymerase%3B Nucleotidyltransferase%3B Transcription%3B Transferase%3B DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B Belongs to the RNA polymerase beta' chain family%3B KEGG: ssdc:SSDC_00130 DNA-directed RNA polymerase subunit beta' gene gene139 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00140 S100027_00141 S100027_00141 S100027_00141 133694 133942 + Putative ribosomal protein L7Ae-like Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L7Ae family gene gene140 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00141 S100027_00142 S100027_00142 S100027_00142 134047 134463 + 30S ribosomal protein S12 Methylation%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B tRNA-binding%3B With S4 and S5 plays an important role in translational accuracy%3B Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits%2C it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8%2C S12 and S17 appears to hold together the shoulder and platform of the 30S subunit%3B Belongs to the ribosomal protein S12P family gene gene141 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00142 S100027_00143 S100027_00143 S100027_00143 134629 135099 + 30S ribosomal protein S7 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B tRNA-binding%3B One of the primary rRNA binding proteins%2C it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center%2C probably blocks exit of the E-site tRNA%3B Belongs to the ribosomal protein S7P family gene gene142 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00143 S100027_00144 S100027_00144 S100027_00144 135149 137227 + Elongation factor G Cytoplasm%3B Elongation factor%3B GTP-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step%2C the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites%2C respectively. Catalyzes the coordinated movement of the two tRNA molecules%2C the mRNA and conformational changes in the ribosome%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene143 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00144 S100027_00145 S100027_00145 S100027_00145 137347 138537 + Elongation factor Tu-A Cytoplasm%3B Elongation factor%3B GTP-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene144 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00145 S100027_00146 S100027_00146 S100027_00146 138859 139167 + 30S ribosomal protein S10%2C chloroplastic Chloroplast%3B Plastid%3B Ribonucleoprotein%3B Ribosomal protein%3B Involved in the binding of tRNA to the ribosomes%3B Belongs to the ribosomal protein S10P family gene gene145 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00146 S100027_00147 S100027_00147 S100027_00147 139206 139835 + 50S ribosomal protein L3 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B One of the primary rRNA binding proteins%2C it binds directly near the 3'-end of the 23S rRNA%2C where it nucleates assembly of the 50S subunit%3B Belongs to the ribosomal protein L3P family gene gene146 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00147 S100027_00148 S100027_00148 S100027_00148 139863 140486 + 50S ribosomal protein L4 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B One of the primary rRNA binding proteins%2C this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome%3B Forms part of the polypeptide exit tunnel%3B Belongs to the ribosomal protein L4P family gene gene147 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00148 S100027_00149 S100027_00149 S100027_00149 140486 140773 + 50S ribosomal protein L23 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome%3B Belongs to the ribosomal protein L23P family gene gene148 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00149 S100027_00150 S100027_00150 S100027_00150 140805 141638 + 50S ribosomal protein L2 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome%2C for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activit%3B this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome%3B Belongs to the ribosomal protein L2P family gene gene149 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00150 S100027_00151 S100027_00151 S100027_00151 141696 141974 + 30S ribosomal protein S19%2C chloroplastic Chloroplast%3B Plastid%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA%3B Belongs to the ribosomal protein S19P family gene gene150 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00151 S100027_00152 S100027_00152 S100027_00152 141992 142336 + 50S ribosomal protein L22 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B This protein binds specifically to 23S rRN%3B its binding is stimulated by other ribosomal proteins%2C e. g. L4%2C L17%2C and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)%3B The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit%2C while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome%3B Belongs to the ribosomal protein L22P family gene gene151 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00152 S100027_00153 S100027_00153 S100027_00153 142340 142996 + 30S ribosomal protein S3%2C chloroplastic Chloroplast%3B Plastid%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Belongs to the ribosomal protein S3P family%3B Contains 1 KH type-2 domain gene gene152 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00153 S100027_00154 S100027_00154 S100027_00154 142998 143432 + 50S ribosomal protein L16%2C plastid Plastid%3B Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L16P family gene gene153 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00154 S100027_00155 S100027_00155 S100027_00155 143422 143622 + 50S ribosomal protein L29 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L29P family gene gene154 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00155 S100027_00156 S100027_00156 S100027_00156 143647 143910 + 30S ribosomal protein S17 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B One of the primary rRNA binding proteins%2C it binds specifically to the 5'-end of 16S ribosomal RNA%3B Belongs to the ribosomal protein S17P family gene gene155 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00156 S100027_00157 S100027_00157 S100027_00157 143951 144319 + 50S ribosomal protein L14 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome%3B Belongs to the ribosomal protein L14P family gene gene156 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00157 S100027_00158 S100027_00158 S100027_00158 144355 144666 + 50S ribosomal protein L24 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B One of two assembly initiator proteins%2C it binds directly to the 5'-end of the 23S rRNA%2C where it nucleates assembly of the 50S subunit%3B One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit%3B Belongs to the ribosomal protein L24P family gene gene157 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00158 S100027_00159 S100027_00159 S100027_00159 144692 145231 + 50S ribosomal protein L5 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B tRNA-binding%3B This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit%2C where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b)%2C connecting the 2 subunit%3B this bridge is implicated in subunit movement. Contacts the P site tRN%3B the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs%3B Belongs to the ribosomal protein L5P family gene gene158 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00159 S100027_00160 S100027_00160 S100027_00160 145254 145439 + 30S ribosomal protein S14 type Z Metal-binding%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Zinc%3B Binds 16S rRNA%2C required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site%3B Belongs to the ribosomal protein S14P family. Zinc- binding S14P subfamily gene gene159 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00160 S100027_00161 S100027_00161 S100027_00161 145471 145869 + 30S ribosomal protein S8 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B One of the primary rRNA binding proteins%2C it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit%3B Belongs to the ribosomal protein S8P family gene gene160 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00161 S100027_00162 S100027_00162 S100027_00162 145899 146435 + 50S ribosomal protein L6%2C cyanelle Cyanelle%3B Plastid%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Binds 23S rRNA%3B Belongs to the ribosomal protein L6P family gene gene161 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00162 S100027_00163 S100027_00163 S100027_00163 146467 146829 + 50S ribosomal protein L18 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit%2C where it forms part of the central protuberance%3B Belongs to the ribosomal protein L18P family gene gene162 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00163 S100027_00164 S100027_00164 S100027_00164 146848 147354 + 30S ribosomal protein Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B With S4 and S12 plays an important role in translational accuracy%3B Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body%3B Belongs to the ribosomal protein S5P family%3B Contains 1 S5 DRBM domain gene gene163 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00164 S100027_00165 S100027_00165 S100027_00165 147368 147547 + 50S ribosomal protein L30 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L30P family gene gene164 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00165 S100027_00166 S100027_00166 S100027_00166 147578 148018 + 50S ribosomal protein L15 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Binds to the 23S rRNA%3B Belongs to the ribosomal protein L15P family gene gene165 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00166 S100027_00167 S100027_00167 S100027_00167 148020 149315 + Protein translocase subunit SecY Cell membrane%3B Membrane%3B Protein transport%3B Translocation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7%2C and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently%3B Belongs to the SecY/SEC61-alpha family gene gene166 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00167 S100027_00168 S100027_00168 S100027_00168 149369 150022 + Adenylate kinase ATP-binding%3B Cytoplasm%3B Kinase%3B Metal-binding%3B Nucleotide biosynthesis%3B Nucleotide-binding%3B Transferase%3B Zinc%3B Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism%3B Belongs to the adenylate kinase family%3B KEGG: cbu:CBU_0454 adenylate kinase gene gene167 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00168 S100027_00169 S100027_00169 S100027_00169 150019 150765 + Methionyl aminopeptidase Aminopeptidase%3B Cytoplasm%3B Hydrolase%3B Metal-binding%3B Protease%3B Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-%2C Cys%2C Gly%2C Pro%2C Ser%2C Thr%2C or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed%3B Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily%3B KEGG: bsu:BSU01380 methionyl aminopeptidase gene gene168 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00169 S100027_00170 S100027_00170 S100027_00170 150776 151105 + Putative ribosome-binding protein YbzG gene gene169 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00170 S100027_00171 S100027_00171 S100027_00171 151083 151301 + Translation initiation factor IF-1 Cytoplasm%3B Initiation factor%3B Protein biosynthesis%3B RNA-binding%3B rRNA-binding%3B One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection%2C yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1%2C IF-2 and IF-3 are released leaving the mature 70S translation initation complex%3B Belongs to the IF-1 family%3B Contains 1 S1-like domain gene gene170 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00171 S100027_00172 S100027_00172 S100027_00172 151335 151448 + 50S ribosomal protein L36%2C chloroplastic Chloroplast%3B Plastid%3B Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L36P family gene gene171 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00172 S100027_00173 S100027_00173 S100027_00173 151471 151836 + Cyanelle 30S ribosomal protein S13 Cyanelle%3B Plastid%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Located at the top of the head of the 30S subunit%2C it contacts several helices of the 16S rRNA%3B Belongs to the ribosomal protein S13P family gene gene172 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00173 S100027_00174 S100027_00174 S100027_00174 151857 152252 + 30S ribosomal protein S11 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Located on the platform of the 30S subunit%2C it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome%3B Belongs to the ribosomal protein S11P family gene gene173 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00174 S100027_00175 S100027_00175 rpoA rpoA 152427 153371 + DNA-directed RNA polymerase DNA-directed RNA polymerase%3B Nucleotidyltransferase%3B Transcription%3B Transferase%3B DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B Belongs to the RNA polymerase alpha chain family%3B KEGG: bsu:BSU01430 DNA-directed RNA polymerase subunit alpha gene gene174 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00175 S100027_00176 S100027_00176 S100027_00176 153449 153811 + 50S ribosomal protein L17 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L17P family gene gene175 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00176 S100027_00177 S100027_00177 S100027_00177 153953 154798 + Energy-coupling factor transporter ATP-binding protein EcfA1 ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the ABC transporter superfamily. Energy- coupling factor EcfA family%3B Contains 1 ABC transporter domain%3B KEGG: bli:BL01023 energy-coupling factor transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene176 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00177 S100027_00178 S100027_00178 S100027_00178 154774 155643 + Energy-coupling factor transporter ATP-binding protein EcfA2 ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the ABC transporter superfamily. Energy- coupling factor EcfA family%3B Contains 1 ABC transporter domain gene gene177 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00178 S100027_00179 S100027_00179 S100027_00179 155640 156437 + Energy-coupling factor transporter transmembrane protein EcfT Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the energy-coupling factor EcfT family gene gene178 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00179 S100027_00180 S100027_00180 truA truA 156448 157191 + tRNA pseudouridine(38-40) synthase Isomerase%3B tRNA processing%3B Formation of pseudouridine at positions 38%2C 39 and 40 in the anticodon stem and loop of transfer RNAs%3B Belongs to the tRNA pseudouridine synthase TruA family%3B KEGG: bsu:BSU01480 tRNA pseudouridine38-40 synthase gene gene179 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00180 S100027_00181 S100027_00181 S100027_00181 157352 157789 + 50S ribosomal protein L13 Ribonucleoprotein%3B Ribosomal protein%3B This protein is one of the early assembly proteins of the 50S ribosomal subunit%2C although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly%3B Belongs to the ribosomal protein L13P family gene gene180 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00181 S100027_00182 S100027_00182 S100027_00182 157810 158202 + 30S ribosomal protein S9 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein S9P family gene gene181 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00182 S100027_00183 S100027_00183 S100027_00183 158253 158711 - uncharacterized protein Metal-binding%3B Belongs to the DinB family gene gene182 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00183 S100027_00184 S100027_00184 S100027_00184 158823 159266 + uncharacterized protein gene gene183 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00184 S100027_00185 S100027_00185 amiA amiA 159359 160072 + N-acetylmuramoyl-L-alanine amidase Cell wall biogenesis/degradation%3B Hydrolase%3B Secreted%3B Signal%3B Cleaves the peptide side chain from the N-acetylmuramic acid residues in peptidoglycan. This is a step in the formation of muramic delta-lactam residues in spore cortex%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B KEGG: bsu:BSU01530 N-acetylmuramoyl-L-alanine amidase gene gene184 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00185 S100027_00186 S100027_00186 S100027_00186 160113 161219 + Iron-sulfur cluster carrier protein ATP-binding%3B Hydrolase%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Nucleotide-binding%3B Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP%3B Negatively regulates the expression of hpr/scoC. The effect on hpr/scoC may be indirect%3B Belongs to the Mrp/NBP35 ATP-binding proteins family gene gene185 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00186 S100027_00187 S100027_00187 S100027_00187 161273 161854 - Spore germination protein GerD Cell membrane%3B Germination%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal. gene gene186 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00187 S100027_00188 S100027_00188 S100027_00188 161969 162568 + KinB-signaling pathway activation protein Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Involved in the activation of the KinB signaling pathway of sporulation gene gene187 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00188 S100027_00189 S100027_00189 pdaA pdaA 162577 163341 - putative polysaccharide deacetylase PdaB Hydrolase%3B Signal%3B Sporulation%3B Necessary to maintain spores after the late stage of sporulation. Might be involved in cortex formation%3B Belongs to the polysaccharide deacetylase family%3B KEGG: css:Cst_c05460 peptidoglycan-N-acetylmuramic acid deacetylase%3B In linear amides gene gene188 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00189 S100027_00190 S100027_00190 S100027_00190 163681 165231 + 16S ribosomal RNA rRNA gene189 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00190 S100027_00191 S100027_00191 S100027_00191 165406 168336 + 23S ribosomal RNA rRNA gene190 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00191 S100027_00192 S100027_00192 S100027_00192 168469 168584 + 5S ribosomal RNA rRNA gene191 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00192 S100027_00193 S100027_00193 S100027_00193 168627 168701 + tRNA-Asn tRNA gene192 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00193 S100027_00194 S100027_00194 S100027_00194 168704 168776 + tRNA-Thr tRNA gene193 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00194 S100027_00195 S100027_00195 S100027_00195 168900 169067 - hypothetical protein gene gene194 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00195 S100027_00196 S100027_00196 S100027_00196 169161 170330 - Putative penicillin-binding protein PbpX Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Belongs to the beta-lactamase family gene gene195 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00196 S100027_00197 S100027_00197 S100027_00197 170505 170726 + hypothetical protein gene gene196 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00197 S100027_00198 S100027_00198 uxaB uxaB 170838 171815 + Tagaturonate reductase Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B KEGG: sbu:SpiBuddy_3010 tagaturonate reductase gene gene197 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00198 S100027_00199 S100027_00199 S100027_00199 171850 172263 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene198 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00199 S100027_00200 S100027_00200 phzF phzF 172279 173148 - Trans-2%2C3-dihydro-3-hydroxyanthranilate isomerase Antibiotic biosynthesis%3B Isomerase%3B Isomerase that catalyzes the condensation of two molecules of trans-2%2C3-dihydro-3-hydroxyanthranilic acid (DHHA) into the phenazine ring system. The final product is not yet known (By similarity)%3B Belongs to the PhzF family%3B KEGG: hdn:Hden_2074 trans-2%2C3-dihydro-3-hydroxyanthranilate isomerase gene gene199 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00200 S100027_00201 S100027_00201 nagZ nagZ 173254 174483 - Beta-N-acetylhexosaminidase Signal%3B KEGG: hhd:HBHAL_2473 beta-N-acetylhexosaminidase%3B overlaps another CDS with the same product name gene gene200 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00201 S100027_00202 S100027_00202 S100027_00202 174483 176414 - Beta-N-acetylhexosaminidase Cell membrane%3B Cell shape%3B Cell wall%3B Cell wall biogenesis/degradation%3B Glycosidase%3B Hydrolase%3B Lipoprotein%3B Membrane%3B Palmitate%3B Peptidoglycan synthesis%3B Secreted%3B Signal%3B Cleaves muropeptides%2C but not peptidoglycan%3B Belongs to the glycosyl hydrolase 3 family%3B KEGG: bli:BL02716 beta-N-acetylhexosaminidase%3B overlaps another CDS with the same product name gene gene201 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00202 S100027_00203 S100027_00203 cwlA cwlA 176430 177776 - N-acetylmuramoyl-L-alanine amidase Signal%3B Belongs to the UPF0214 family%3B KEGG: pat:Patl_4160 N-acetylmuramoyl-L-alanine amidase gene gene202 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00203 S100027_00204 S100027_00204 scrA scrA 177844 179211 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell inner membrane%3B Cell membrane%3B Kinase%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in arbutin%2C cellobiose%2C and salicin transport. Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bli:BL02718 PTS system%2C sucrose-specific IIB component gene gene203 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00204 S100027_00205 S100027_00205 S100027_00205 179238 180086 - putative HTH-type transcriptional regulator YbbH DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH rpiR-type DNA-binding domain%3B Contains 1 SIS domain gene gene204 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00205 S100027_00206 S100027_00206 murQ murQ 180105 181019 - N-acetylmuramic acid 6-phosphate etherase Carbohydrate metabolism%3B Lyase%3B Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate%2C producing GlcNAc 6- phosphate and D-lactate%3B Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily%3B Contains 1 SIS domain%3B KEGG: bli:BL02720 N-acetylmuramic acid 6-phosphate etherase gene gene205 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00206 S100027_00207 S100027_00207 S100027_00207 181194 181646 - uncharacterized protein gene gene206 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00207 S100027_00208 S100027_00208 S100027_00208 181830 181904 + tRNA-Glu tRNA gene207 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00208 S100027_00209 S100027_00209 S100027_00209 182055 182130 + tRNA-Val tRNA gene208 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00209 S100027_00210 S100027_00210 S100027_00210 182189 182261 + tRNA-Thr tRNA gene209 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00210 S100027_00211 S100027_00211 S100027_00211 182270 182354 + tRNA-Tyr tRNA gene210 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00211 S100027_00212 S100027_00212 S100027_00212 182359 182430 + tRNA-Gln tRNA gene211 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00212 S100027_00213 S100027_00213 rocF rocF 182556 183470 + Arginase Arginine metabolism%3B Hydrolase%3B Manganese%3B Metal-binding%3B Belongs to the arginase family%3B KEGG: bli:BL02698 arginase gene gene212 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00213 S100027_00214 S100027_00214 S100027_00214 183696 184259 + ECF RNA polymerase sigma factor SigW DNA-binding%3B Sigma factor%3B Stress response%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma factors are held in an inactive form by a cognate anti-sigma factor (RsiW for this protein) until released by regulated membrane proteolysis. Sigma-W controls genes involved in transport processes and detoxification%3B Belongs to the sigma-70 factor family. ECF subfamily gene gene213 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00214 S100027_00215 S100027_00215 S100027_00215 184303 184893 + Anti-sigma-W factor RsiW Membrane%3B Metal-binding%3B Transmembrane%3B Transmembrane helix%3B Zinc%3B Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW%2C and its proteolytic destruction to sigma-W activation (By similarity)%3B Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family gene gene214 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00215 S100027_00216 S100027_00216 dacA dacA 185059 185880 + Diadenylate cyclase Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B KEGG: bsu:BSU01750 diadenylate cyclase gene gene215 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00216 S100027_00217 S100027_00217 S100027_00217 185873 187189 + YbbR-like domain-containing protein YbbR Repeat%3B Signal%3B Contains 4 YbbR-like domains gene gene216 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00217 S100027_00218 S100027_00218 glmM glmM 187210 188556 + Phosphoglucosamine mutase Isomerase%3B Magnesium%3B Metal-binding%3B Phosphoprotein%3B Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate%3B Belongs to the phosphohexose mutase family%3B KEGG: scu:SCE1572_24625 phosphoglucosamine mutase gene gene217 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00218 S100027_00219 S100027_00219 glmS glmS 188998 190800 + Glutamine--fructose-6-phosphate transaminase (isomerizing) Aminotransferase%3B Cytoplasm%3B Glutamine amidotransferase%3B Repeat%3B Transferase%3B Catalyzes the first step in hexosamine metabolism%2C converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source%3B Contains 1 glutamine amidotransferase type-2 domain%3B Contains 2 SIS domains%3B KEGG: alv:Alvin_0239 glucosamine--fructose-6-phosphate aminotransferase (isomerizing) gene gene218 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00219 S100027_00220 S100027_00220 S100027_00220 190991 191314 + hypothetical protein gene gene219 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00220 S100027_00221 S100027_00221 S100027_00221 191457 192065 - hypothetical protein gene gene220 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00221 S100027_00222 S100027_00222 S100027_00222 192046 192927 - putative ABC transporter ATP-binding protein ATP-binding%3B Nucleotide-binding%3B Repeat%3B Transport%3B Belongs to the ABC transporter superfamily%3B Contains 2 ABC transporter domains gene gene221 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00222 S100027_00223 S100027_00223 S100027_00223 192927 193304 - putative HTH-type transcriptional regulator YhdI Aminotransferase%3B DNA-binding%3B Pyridoxal phosphate%3B Transcription%3B Transcription regulation%3B Transferase%3B In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene222 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00223 S100027_00224 S100027_00224 S100027_00224 193485 193787 + putative HTH-type transcriptional regulator YbzH DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH arsR-type DNA-binding domain gene gene223 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00224 S100027_00225 S100027_00225 S100027_00225 193932 195104 + Putative multidrug resistance protein MdtD Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily. TCR/Tet family gene gene224 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00225 S100027_00226 S100027_00226 S100027_00226 195353 195757 - hypothetical protein gene gene225 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00226 S100027_00227 S100027_00227 abcA abcA 195786 197522 - Xenobiotic-transporting ATPase Antibiotic resistance%3B ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B An efflux transporter able to transport Hoechst 33342%2C ethidium bromide%2C doxorubicin and a number of other drugs in vitro into inside out vesicles. The endogenous substrate is unknown. It has been suggested that NBD dimerization induced by ATP-binding causes a large conformational change responsible for substrate translocation (PubMed:18215075). Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (Probable)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain%3B KEGG: bli:BL02726 ATP-binding cassette%2C subfamily B%2C bacterial AbcA/BmrA gene gene226 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00227 S100027_00228 S100027_00228 S100027_00228 197717 198361 + uncharacterized protein gene gene227 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00228 S100027_00229 S100027_00229 S100027_00229 198435 198854 + hypothetical protein gene gene228 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00229 S100027_00230 S100027_00230 S100027_00230 198929 199453 + hypothetical protein gene gene229 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00230 S100027_00231 S100027_00231 aadK aadK 199562 200440 + Aminoglycoside 6-adenylyltransferase Transferase%3B To E. faecalis AadE%3B KEGG: bsu:BSU26790 aminoglycoside 6-adenylyltransferase%3B Nucleotidyltransferases gene gene230 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00231 S100027_00232 S100027_00232 S100027_00232 200496 201443 + hypothetical protein gene gene231 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00232 S100027_00233 S100027_00233 S100027_00233 201466 202185 + (S)-2-haloacid dehalogenase Hydrolase%3B Belongs to the HAD-like hydrolase superfamily. YjjG family%3B KEGG: bli:BL02712 2-haloacid dehalogenase gene gene232 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00233 S100027_00234 S100027_00234 S100027_00234 202479 203849 + putative transporter YbxG Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probable amino-acid or metabolite transport protein. Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene233 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00234 S100027_00235 S100027_00235 S100027_00235 204233 205531 - Mg(2+)/citrate complex secondary transporter Cell membrane%3B Citrate utilization%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Proton motive force-driven secondary transporter that mediates the transport of citrate complexed to Mg(2+). Cotransports at least two protons per Mg(2+)-citrate complex. Can also transport citrate in complex with Ni(2+)%2C Mn(2+)%2C Co(2+)%2C and Zn(2+). Belongs to the CitM (TC 2. A. 11) transporter family gene gene234 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00235 S100027_00236 S100027_00236 S100027_00236 205736 206695 - UPF0065 protein YflP Signal%3B Belongs to the UPF0065 (bug) family gene gene235 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00236 S100027_00237 S100027_00237 S100027_00237 206698 207378 - putative C4-dicarboxylate response regulator DctR Activator%3B Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system DctS/DctR. Essential for expression of DctP (By similarity)%3B Contains 1 response regulatory domain gene gene236 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00237 S100027_00238 S100027_00238 citS citS 207375 208991 - Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system CitT/CitS. Regulates the expression of the citM-yflN operon. Functions probably as a membrane-associated protein kinase that phosphorylates CitT in response to environmental citrate or Mg(2+)-citrate complex%3B Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bld:BLi00225 two-component system%2C CitB family%2C sensor histidine kinase CitS gene gene237 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00238 S100027_00239 S100027_00239 S100027_00239 209489 210385 - HTH-type transcriptional activator AllS Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Positive regulator essential for the expression of allD operon. Binds to the allD promoter (By similarity)%3B Contains 1 HTH lysR-type DNA-binding domain gene gene238 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00239 S100027_00240 S100027_00240 bacD bacD 210508 211725 + L-alanine--L-anticapsin ligase ATP-binding%3B Cobalt%3B Ligase%3B Magnesium%3B Manganese%3B Metal-binding%3B Nucleotide-binding%3B Catalyzes the synthesis of Arg-Xaa dipeptides in an ATP- dependent manner. Has strict specificity toward arginine as the N- terminal substrate%3B Contains 1 ATP-grasp domain%3B KEGG: bpu:BPUM_3423 L-alanine-L-anticapsin ligase gene gene239 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00240 S100027_00241 S100027_00241 S100027_00241 211799 212935 + putative MFS-type transporter YdeE Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the major facilitator superfamily gene gene240 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00241 S100027_00242 S100027_00242 S100027_00242 213006 213254 + Sigma-G-dependent sporulation-specific SASP protein Sporulation. gene gene241 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00242 S100027_00243 S100027_00243 S100027_00243 213271 213462 + uncharacterized protein gene gene242 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00243 S100027_00244 S100027_00244 S100027_00244 213583 213849 - uncharacterized protein Signal. gene gene243 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00244 S100027_00245 S100027_00245 S100027_00245 213907 215964 - uncharacterized protein gene gene244 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00245 S100027_00246 S100027_00246 S100027_00246 216194 216643 + SPBc2 prophage-derived putative transcriptional regulator YosT gene gene245 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00246 S100027_00247 S100027_00247 S100027_00247 216934 217107 - Spermatoproteinis-associated protein Developmental protein%3B Differentiation%3B Phosphoprotein%3B Secreted%3B Spermatogenesis%3B May play a role in fertility regulation gene gene246 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00247 S100027_00248 S100027_00248 S100027_00248 217834 219117 + putative MFS-type transporter YdeG Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene247 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00248 S100027_00249 S100027_00249 chlM chlM 219142 219915 - Magnesium protoporphyrin IX methyltransferase KEGG: hmo:HM1_0689 magnesium-protoporphyrin O-methyltransferase gene gene248 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00249 S100027_00250 S100027_00250 qorB qorB 220083 220955 + NAD(P)H dehydrogenase (quinone) NADP%3B Oxidoreductase%3B Quinone oxidoreductase that may play some additional role beyond quinone reduction. Potential redox sensor protein. Overexpression induces retardation of growth%3B Belongs to the NmrA-type oxidoreductase family%3B KEGG: pfe:PSF113_2585 NAD(P)H dehydrogenase (quinone) gene gene249 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00250 S100027_00251 S100027_00251 S100027_00251 221310 221816 - hypothetical protein gene gene250 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00251 S100027_00252 S100027_00252 S100027_00252 222054 223688 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B To B. subtilis YqeW gene gene251 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00252 S100027_00253 S100027_00253 S100027_00253 223839 224099 + putative membrane protein YubF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene252 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00253 S100027_00254 S100027_00254 S100027_00254 224251 224586 - hypothetical protein gene gene253 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00254 S100027_00255 S100027_00255 S100027_00255 224656 225102 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene254 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00255 S100027_00256 S100027_00256 S100027_00256 225139 225606 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene255 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00256 S100027_00257 S100027_00257 S100027_00257 225920 226339 - hypothetical protein gene gene256 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00257 S100027_00258 S100027_00258 S100027_00258 226336 227244 - putative transporter YbhF Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene257 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00258 S100027_00259 S100027_00259 S100027_00259 227241 228077 - putative HTH-type transcriptional regulator YbfI DNA-binding%3B Repeat%3B Transcription%3B Transcription regulation%3B Contains 1 HTH araC/xylS-type DNA-binding domain gene gene258 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00259 S100027_00260 S100027_00260 S100027_00260 228193 228606 + hypothetical protein gene gene259 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00260 S100027_00261 S100027_00261 S100027_00261 228668 229135 + hypothetical protein gene gene260 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00261 S100027_00262 S100027_00262 S100027_00262 229270 229887 - hypothetical protein gene gene261 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00262 S100027_00263 S100027_00263 ybdH ybdH 230026 231081 + Glycerol dehydrogenase Glycerol metabolism%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Zinc%3B Catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone (glycerone). Allows microorganisms to utilize glycerol as a source of carbon under anaerobic conditions. Is also able to use various diols as substrates%2C such as propan-1%2C2-diol%2C butan-2%2C3-diol%2C ethan-1%2C2-diol%2C and 3-mercapto-1%2C2- dihydroxypropane%3B Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: bli:BL00169 uncharacterized oxidoreductase%3B Acting on the CH-OH group of donors gene gene262 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00263 S100027_00264 S100027_00264 S100027_00264 231254 232960 + Methyl-accepting chemotaxis protein Cell membrane%3B Chemotaxis%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene263 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00264 S100027_00265 S100027_00265 S100027_00265 232986 234050 + D-xylose-binding periplasmic protein Periplasm%3B Signal%3B Sugar transport%3B Transport%3B Involved in the high-affinity D-xylose membrane transport system. Binds with high affinity to xylose. Belongs to the bacterial solute-binding protein 2 family gene gene264 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00265 S100027_00266 S100027_00266 ppiC ppiC 234089 234856 - Peptidylprolyl isomerase KEGG: gpi:GPICK_07635 peptidyl-prolyl cis-trans isomerase C gene gene265 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00266 S100027_00267 S100027_00267 S100027_00267 235011 235775 - hypothetical protein gene gene266 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00267 S100027_00268 S100027_00268 S100027_00268 236100 236987 + Virginiamycin B lyase Antibiotic resistance%3B Lyase%3B Magnesium%3B Metal-binding%3B Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage%2C generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid%3B Belongs to the Vgb family%3B KEGG: bli:BL01635 virginiamycin B lyase%3B Other carbon-oxygen lyases gene gene267 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00268 S100027_00269 S100027_00269 S100027_00269 237024 237404 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene268 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00269 S100027_00270 S100027_00270 S100027_00270 237431 238885 - Leu/Val/Ile amino-acid permease Amino-acid transport%3B Cell membrane%3B Membrane%3B Phosphoprotein%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Permease for leucine%2C valine and isoleucine. Also transports cysteine%2C methionine%2C phenyalanine%2C tyrosine and tryptophan%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2. A. 3. 10) family gene gene269 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00270 S100027_00271 S100027_00271 mmuM mmuM 238885 239832 - Homocysteine S-methyltransferase Amino-acid biosynthesis%3B Metal-binding%3B Methionine biosynthesis%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Zinc%3B Contains 1 Hcy-binding domain%3B KEGG: bli:BL01781 homocysteine S-methyltransferase gene gene270 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00271 S100027_00272 S100027_00272 chbG chbG 240042 240782 + Chitin disaccharide deacetylase Carbohydrate metabolism%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides%3B Belongs to the YdjC deacetylase family%3B KEGG: dgg:DGI_1411 chitin disaccharide deacetylase gene gene271 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00272 S100027_00273 S100027_00273 nagE nagE 240796 242169 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Kinase%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity). This system may be involved in glucosamine transport%3B Contains 1 PTS EIIA type-1 domain%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bli:BL01637 PTS system%2C N-acetylglucosamine-specific IIB component gene gene272 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00273 S100027_00274 S100027_00274 queF queF 242258 243067 + PreQ(1) synthase Activator%3B Coiled coil%3B Cytoplasm%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Global transcriptional regulator that activates transcription of bmr and blt by binding directly to their promoter. Stimulates also the expression of the mta gene itself%2C ydfK and ymfE%3B Contains 1 HTH merR-type DNA-binding domain%3B KEGG: llo:LLO_0515 7-cyano-7-deazaguanine reductase gene gene273 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00274 S100027_00275 S100027_00275 S100027_00275 243110 243832 - UPF0702 transmembrane protein YrbG Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0702 family gene gene274 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00275 S100027_00276 S100027_00276 S100027_00276 243820 244530 - Carbonic anhydrase Lyase%3B Metal-binding%3B Signal%3B Zinc%3B Reversible hydration of carbon dioxide. Essential to photosynthetic carbon dioxide fixation. Belongs to the gamma-class carbonic anhydrase family gene gene275 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00276 S100027_00277 S100027_00277 S100027_00277 245054 245449 - putative membrane protein YjgA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene276 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00277 S100027_00278 S100027_00278 S100027_00278 245594 247024 - putative sodium/glutamine symporter GlnT Amino-acid transport%3B Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably functions as a sodium/glutamine symporter for glutamine uptake%3B Belongs to the sodium:alanine (SAF) symporter family gene gene277 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00278 S100027_00279 S100027_00279 glsA glsA 247049 248032 - Glutaminase Hydrolase%3B Belongs to the glutaminase family%3B KEGG: bli:BL01786 glutaminase gene gene278 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00279 S100027_00280 S100027_00280 ycbA ycbA 248425 249750 + Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system GlnK/GlnL that positively regulates the expression of the glsA-glnT operon in response to glutamine. Probably activates GlnL by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bli:BL01640 two-component system%2C sensor histidine kinase YcbA gene gene279 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00280 S100027_00281 S100027_00281 S100027_00281 249757 250692 + Transcriptional regulatory protein GlnL Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system GlnL/GlnK that positively regulates the expression of the glsA-glnT operon in response to glutamine. GlnL binds the promoter region of glsA- glnT in vitro%3B Contains 1 response regulatory domain gene gene280 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00281 S100027_00282 S100027_00282 rimJ rimJ 250735 251271 - Ribosomal-protein-alanine N-acetyltransferase Acyltransferase%3B Transferase%3B Contains 1 N-acetyltransferase domain%3B KEGG: bli:BL01787 ribosomal-protein-alanine N-acetyltransferase gene gene281 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00282 S100027_00283 S100027_00283 S100027_00283 251367 253166 - Regulatory protein BlaR1 Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B BlaR1 is a potential penicillin-binding protein required for induction of beta-lactamase in Bacillus licheniformis. Belongs to the peptidase M56 family gene gene282 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00283 S100027_00284 S100027_00284 S100027_00284 253168 253554 - Penicillinase repressor Antibiotic resistance%3B Cytoplasm%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcriptional repressor that constitutively blocks expression of beta-lactamase. Regulates genes involved in antibiotic resistance. Binds DNA as a dimer. Belongs to the BlaI transcriptional regulatory family gene gene283 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00284 S100027_00285 S100027_00285 penP penP 253977 254900 + Beta-lactamase Antibiotic resistance%3B Cell membrane%3B Hydrolase%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Belongs to the class-A beta-lactamase family%3B KEGG: bli:BL01642 beta-lactamase class A gene gene284 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00285 S100027_00286 S100027_00286 phoD phoD 255245 256996 + Alkaline phosphatase Hydrolase%3B Signal%3B Stress response%3B Belongs to the PhoD family%3B KEGG: bli:BL01643 alkaline phosphatase D gene gene285 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00286 S100027_00287 S100027_00287 S100027_00287 257018 257230 + Sec-independent protein translocase protein TatAd Cell membrane%3B Cytoplasm%3B Membrane%3B Protein transport%3B Translocation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. Required for PhoD secretion. The cytosolic fraction of TatAd binds the precursor of PhoD%3B Belongs to the TatA/E family gene gene286 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00287 S100027_00288 S100027_00288 S100027_00288 257301 258035 + Sec-independent protein translocase protein TatCd Cell membrane%3B Membrane%3B Protein transport%3B Translocation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Required for PhoD secretion. TatCd promotes membrane localization of TatAd via domain specific interactions. TatCd is required for stabile production of TatAd as well as for its maintenance%3B Belongs to the TatC family gene gene287 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00288 S100027_00289 S100027_00289 kdgD kdgD 258231 259157 + 5-dehydro-4-deoxyglucarate dehydratase Lyase%3B Belongs to the DapA family%3B KEGG: bli:BL01645 5-dehydro-4-deoxyglucarate dehydratase gene gene288 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00289 S100027_00290 S100027_00290 S100027_00290 259179 260645 + Aldehyde dehydrogenase (NAD(+)) NAD%3B Oxidoreductase%3B Oxidizes several aliphatic aldehydes%2C particularly c6- aliphatic aldehyde and hexanal%2C but does not oxidize benzaldehyde. Belongs to the aldehyde dehydrogenase family%3B KEGG: bli:BL01646 aldehyde dehydrogenase (NAD+) gene gene289 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00290 S100027_00291 S100027_00291 S100027_00291 260686 262062 + putative glucarate transporter Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Uptake of D-glucarate. Belongs to the major facilitator superfamily. Phthalate permease family gene gene290 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00291 S100027_00292 S100027_00292 gudD gudD 262100 263467 + Glucarate dehydratase Lyase%3B Magnesium%3B Metal-binding%3B Catalyzes the dehydration of glucarate to 5-keto-4- deoxy-D-glucarate (5-kdGluc)%3B Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily%3B KEGG: bli:BL01649 glucarate dehydratase gene gene291 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00292 S100027_00293 S100027_00293 S100027_00293 263562 264275 + putative HTH-type transcriptional regulator YcbG DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH gntR-type DNA-binding domain gene gene292 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00293 S100027_00294 S100027_00294 garD garD 264364 265890 + Galactarate dehydratase Lyase%3B Catalyzes the dehydration of galactarate to form 5- dehydro-4-deoxy-D-glucarate%3B Belongs to the UxaA family%3B KEGG: bli:BL01651 galactarate dehydratase gene gene293 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00294 S100027_00295 S100027_00295 S100027_00295 266053 266745 + Regulatory protein VirG Activator%3B Crown gall tumor%3B Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Plasmid%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B VirG is required for the positive regulation of at least two vir loci encoded by the Ti plasmid of A. tumefaciens. Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene294 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00295 S100027_00296 S100027_00296 S100027_00296 266747 267682 + Sensor histidine kinase YcbM ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system YcbM/YcbL. Probably activates YcbL by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bcz:BCZK0257 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene295 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00296 S100027_00297 S100027_00297 S100027_00297 267777 268700 + putative ABC transporter ATP-binding protein YcbN ATP-binding%3B Nucleotide-binding%3B Transport%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene296 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00297 S100027_00298 S100027_00298 S100027_00298 268715 269398 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene297 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00298 S100027_00299 S100027_00299 S100027_00299 269414 270112 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene298 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00299 S100027_00300 S100027_00300 S100027_00300 270208 271287 + uncharacterized protein gene gene299 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00300 S100027_00301 S100027_00301 S100027_00301 271445 272629 + uncharacterized protein gene gene300 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00301 S100027_00302 S100027_00302 S100027_00302 273030 273941 + uncharacterized protein ATP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the aminoglycoside phosphotransferase family gene gene301 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00302 S100027_00303 S100027_00303 S100027_00303 273975 274394 - Organic hydroperoxide resistance transcriptional regulator Cytoplasm%3B DNA-binding%3B Oxidation%3B Repressor%3B Transcription%3B Transcription regulation%3B Organic peroxide sensor. Represses the expression of the peroxide-inducible gene ohrA by cooperative binding to two inverted repeat elements%3B Contains 1 HTH marR-type DNA-binding domain gene gene302 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00303 S100027_00304 S100027_00304 acsL acsL 274672 276183 + Long-chain-fatty-acid--CoA ligase ATP-binding%3B Ligase%3B Nucleotide-binding%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bca:BCE_3436 long-chain acyl-CoA synthetase gene gene303 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00304 S100027_00305 S100027_00305 S100027_00305 276312 277526 + Alpha-1-antitrypsin-like protein CM55-MM Glycoprotein%3B Phosphoprotein%3B Protease inhibitor%3B Pyrrolidone carboxylic acid%3B Secreted%3B Serine protease inhibitor%3B Signal%3B Protease inhibitor%3B Belongs to the serpin family gene gene304 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00305 S100027_00306 S100027_00306 S100027_00306 277637 278464 + hypothetical protein gene gene305 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00306 S100027_00307 S100027_00307 S100027_00307 278528 279355 + hypothetical protein gene gene306 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00307 S100027_00308 S100027_00308 S100027_00308 279485 280237 + HTH-type transcriptional activator mta Activator%3B Coiled coil%3B Cytoplasm%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Global transcriptional regulator that activates transcription of bmr and blt by binding directly to their promoter. Stimulates also the expression of the mta gene itself%2C ydfK and ymfE%3B Contains 1 HTH merR-type DNA-binding domain gene gene307 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00308 S100027_00309 S100027_00309 S100027_00309 280450 280629 + hypothetical protein gene gene308 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00309 S100027_00310 S100027_00310 S100027_00310 280646 280993 + hypothetical protein gene gene309 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00310 S100027_00311 S100027_00311 S100027_00311 280986 281501 + hypothetical protein gene gene310 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00311 S100027_00312 S100027_00312 S100027_00312 281918 282079 + Tryptophan RNA-binding attenuator protein inhibitory protein Cytoplasm%3B Repeat%3B Transcription%3B Transcription regulation. gene gene311 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00312 S100027_00313 S100027_00313 S100027_00313 282099 283043 + putative transporter YcbK Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the EamA transporter family%3B Contains 1 EamA domain gene gene312 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00313 S100027_00314 S100027_00314 S100027_00314 283096 283488 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene313 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00314 S100027_00315 S100027_00315 S100027_00315 283702 284769 + uncharacterized protein ATP-binding%3B Nucleotide-binding. gene gene314 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00315 S100027_00316 S100027_00316 afuC afuC 284892 285611 + Fe(3+)-transporting ATPase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3. A. 1. 14. 5) family%3B Contains 1 ABC transporter domain%3B KEGG: pkc:PKB_1433 iron(III) transport system ATP-binding protein gene gene315 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00316 S100027_00317 S100027_00317 S100027_00317 285608 286366 + hypothetical protein gene gene316 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00317 S100027_00318 S100027_00318 S100027_00318 286368 287138 + hypothetical protein gene gene317 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00318 S100027_00319 S100027_00319 S100027_00319 287160 287822 + Transcriptional regulatory protein CpxR like protein Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of a two-component regulatory system%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene318 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00319 S100027_00320 S100027_00320 S100027_00320 287813 289183 + Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system SpaK/SpaR involved in the regulation of the biosynthesis of lantibiotic subtilin. SpaK may function as a membrane-associated protein kinase that phosphorylates SpaR in response to environmental signals. Contains 1 histidine kinase domain%3B KEGG: bmq:BMQ_2600 histidine kinase gene gene319 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00320 S100027_00321 S100027_00321 S100027_00321 289256 290140 - HTH-type transcriptional regulator YtlI Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Positively regulates the expression of ytmI operon in response to the availability of sulfur sources%3B Contains 1 HTH lysR-type DNA-binding domain gene gene320 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00321 S100027_00322 S100027_00322 praC praC 290250 290663 + 2-hydroxymuconate tautomerase Isomerase%3B Belongs to the 4-oxalocrotonate tautomerase family%3B KEGG: bte:BTH_II0588 4-oxalocrotonate tautomerase gene gene321 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00322 S100027_00323 S100027_00323 fabG fabG 290647 291387 + 3-oxoacyl-[acyl-carrier-protein] reductase Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B NADP%3B Oxidoreductase%3B Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products%2C the first reductive step in the elongation cycle of fatty acid biosynthesis%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: sfd:USDA257_c20310 3-oxoacyl-(acyl-carrier protein) reductase gene gene322 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00323 S100027_00324 S100027_00324 S100027_00324 291475 293559 + hypothetical protein gene gene323 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00324 S100027_00325 S100027_00325 S100027_00325 293570 294646 - putative lipoprotein YcdA Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal. gene gene324 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00325 S100027_00326 S100027_00326 S100027_00326 295262 296662 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B To E. coli YfcC and H. influenzae HI_0594 gene gene325 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00326 S100027_00327 S100027_00327 S100027_00327 296787 297962 + Peptidase M20 domain-containing protein Polymorphism%3B Belongs to the peptidase M20A family%3B KEGG: tep:TepRe1_0059 amidohydrolase%3B In linear amides gene gene326 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00327 S100027_00328 S100027_00328 S100027_00328 298174 298626 - putative N-acetyltransferase YvbK Acyltransferase%3B Transferase%3B Probable N-acetyltransferase. Contains 1 N-acetyltransferase domain%3B KEGG: vfi:VF_A0653 null%3B Transferring groups other than amino-acyl groups gene gene327 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00328 S100027_00329 S100027_00329 amiE amiE 298726 300225 + Amidase ATP-binding%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)%3B Belongs to the amidase family. GatA subfamily%3B KEGG: blh:BaLi_c03450 amidase gene gene328 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00329 S100027_00330 S100027_00330 pepF pepF 300248 302083 - Oligoendopeptidase F like protein Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Zinc%3B Belongs to the peptidase M3B family%3B KEGG: thl:TEH_06790 oligoendopeptidase F%3B Metalloendopeptidases gene gene329 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00330 S100027_00331 S100027_00331 S100027_00331 302196 302465 - UPF0410 protein YwzA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0410 family gene gene330 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00331 S100027_00332 S100027_00332 S100027_00332 302636 304351 + Serine-type D-Ala-D-Ala carboxypeptidase Antibiotic resistance%3B Cell membrane%3B Cell wall biogenesis/degradation%3B Membrane%3B Signal%3B Affects the methicillin resistance level and autolysis in the presence of Triton X-100 as well as the cell wall structure but its precise function is unknown%3B KEGG: riv:Riv7116_5464 D-alanyl-D-alanine carboxypeptidase gene gene331 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00332 S100027_00333 S100027_00333 S100027_00333 304411 305733 - putative glycolate oxidase iron-sulfur subunit 4Fe-4S%3B Electron transport%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Repeat%3B Transport%3B Contains 2 4Fe-4S ferredoxin-type domains gene gene332 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00333 S100027_00334 S100027_00334 glcD glcD 305730 307142 - (S)-2-hydroxy-acid oxidase FAD%3B Flavoprotein%3B Oxidoreductase%3B Belongs to the FAD-binding oxidoreductase/transferase type 4 family%3B Contains 1 FAD-binding PCMH-type domain%3B KEGG: bli:BL01799 glycolate oxidase gene gene333 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00334 S100027_00335 S100027_00335 celA celA 307266 307568 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cytoplasm%3B Kinase%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in cellobiose transport. Contains 1 PTS EIIB type-3 domain%3B KEGG: bli:BL01800 PTS system%2C cellobiose-specific IIB component%3B overlaps another CDS with the same product name gene gene334 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00335 S100027_00336 S100027_00336 celC celC 307565 307897 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cytoplasm%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in lichenan transport. Contains 1 PTS EIIA type-3 domain%3B KEGG: bli:BL01801 PTS system%2C cellobiose-specific IIA component%3B overlaps another CDS with the same product name gene gene335 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00336 S100027_00337 S100027_00337 S100027_00337 307914 309200 - Cellobiose permease IIC component Cell membrane%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in cellobiose transport. Contains 1 PTS EIIC type-3 domain gene gene336 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00337 S100027_00338 S100027_00338 celF celF 309187 310521 - 6-phospho-beta-glucosidase Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Manganese%3B Metal-binding%3B NAD%3B Hydrolyzes cellobiose 6'-phosphate into glucose 6- phosphate (Glc6P) and glucose. Belongs to the glycosyl hydrolase 4 family%3B KEGG: hav:AT03_20490 6-phospho-beta-glucosidase gene gene337 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00338 S100027_00339 S100027_00339 S100027_00339 310683 311411 + HTH-type transcriptional regulator GmuR Cytoplasm%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcriptional repressor of the gmuBACDREFG operon which is involved in the uptake and degradation of glucomannan%3B Contains 1 HTH gntR-type DNA-binding domain gene gene338 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00339 S100027_00340 S100027_00340 S100027_00340 311416 312150 + Chitin disaccharide deacetylase Carbohydrate metabolism%3B Chitin degradation%3B Cytoplasm%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Polysaccharide degradation%3B Involved in the degradation of chitin. ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer%2C the deacetylated form of chitobiose. Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho- beta-glucosidase ChbF. Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P%2C the inducer of ChbR and the substrate of ChbF%3B Belongs to the YdjC deacetylase family. ChbG subfamily%3B KEGG: blh:BaLi_c03560 chitin disaccharide deacetylase gene gene339 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00340 S100027_00341 S100027_00341 S100027_00341 312562 314349 + Chitinase Carbohydrate metabolism%3B Chitin degradation%3B Glycosidase%3B Hydrolase%3B Polysaccharide degradation%3B Repeat%3B Signal%3B Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily%3B Contains 2 fibronectin type-III domains%3B KEGG: bli:BL01685 chitinase gene gene340 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00341 S100027_00342 S100027_00342 S100027_00342 314440 314922 + Chitinase Carbohydrate metabolism%3B Chitin degradation%3B Glycosidase%3B Hydrolase%3B Periplasm%3B Polysaccharide degradation%3B Signal%3B Hydrolyzes chitin oligosaccharide%3B (GlcNAc)4 to (GlcNAc)2 and (GlcNAc)5%2C6 to (GlcNAc)2 and (GlcNAc)3. Inactive towards chitin%2C glucosamine oligosaccharides%2C glycoproteins and glycopeptides containing (GlcNAc)2. Belongs to the glycosyl hydrolase 18 family%3B KEGG: bli:BL01686 chitinase%3B overlaps another CDS with the same product name gene gene341 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00342 S100027_00343 S100027_00343 S100027_00343 314919 316520 + Chitinase Carbohydrate metabolism%3B Chitin degradation%3B Glycosidase%3B Hydrolase%3B Periplasm%3B Polysaccharide degradation%3B Signal%3B Hydrolyzes chitin oligosaccharide%3B (GlcNAc)4 to (GlcNAc)2 and (GlcNAc)5%2C6 to (GlcNAc)2 and (GlcNAc)3. Inactive towards chitin%2C glucosamine oligosaccharides%2C glycoproteins and glycopeptides containing (GlcNAc)2. Belongs to the glycosyl hydrolase 18 family%3B KEGG: bli:BL01686 chitinase%3B overlaps another CDS with the same product name gene gene342 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00343 S100027_00344 S100027_00344 sspA sspA 316579 317529 - Glutamyl endopeptidase Disulfide bond%3B Hydrolase%3B Protease%3B Secreted%3B Serine protease%3B Signal%3B Specific for hydrolysis of peptide bonds on the carboxyl side of acidic amino acid residues%2C with a strong preference for Glu. Belongs to the peptidase S1B family%3B KEGG: bli:BL01804 glutamyl endopeptidase gene gene343 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00344 S100027_00345 S100027_00345 S100027_00345 317701 318474 + Glucose 1-dehydrogenase (NAD(P)(+)) NADP%3B Oxidoreductase%3B Rhamnose metabolism%3B Involved in the non-phosphorylated metabolic pathway of L-rhamnose catabolism. Catalyzes the oxidation of L-rhamnose to yield L-rhamnono-1%2C4-lactone. It can also oxidize L-lyxose and L- mannose%2C and uses only NADP%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: eta:ETA_30410 glucose 1-dehydrogenase gene gene344 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00345 S100027_00346 S100027_00346 S100027_00346 318641 319459 + hypothetical protein gene gene345 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00346 S100027_00347 S100027_00347 S100027_00347 319559 320956 + uncharacterized protein To B. subtilis YcdC gene gene346 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00347 S100027_00348 S100027_00348 mpsT mpsT 321010 321861 - Thiosulfate sulfurtransferase Repeat%3B Transferase%3B Contains 2 rhodanese domains%3B KEGG: bli:BL01805 thiosulfate/3-mercaptopyruvate sulfurtransferase gene gene347 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00348 S100027_00349 S100027_00349 cwlJ cwlJ 322019 322447 + N-acetylmuramoyl-L-alanine amidase Cell wall biogenesis/degradation%3B Germination%3B Hydrolase%3B Secreted%3B Sporulation%3B Probable spore cortex-lytic enzyme involved in the depolymerization of cortex peptidoglycan during germination. Belongs to the CwlJ family%3B KEGG: bli:BL01690 N-acetylmuramoyl-L-alanine amidase gene gene348 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00349 S100027_00350 S100027_00350 S100027_00350 322494 323486 - uncharacterized protein To bacterial alkanal monooxygenase alpha and beta chains%3B KEGG: gfo:GFO_3489 null%3B Oxidoreductases gene gene349 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00350 S100027_00351 S100027_00351 S100027_00351 323795 325153 + Peptidoglycan DL-endopeptidase CwlO Cell wall biogenesis/degradation%3B Hydrolase%3B Secreted%3B Signal%3B Shows a cell wall hydrolytic DL-endopeptidase activity%3B Belongs to the peptidase C40 family gene gene350 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00351 S100027_00352 S100027_00352 S100027_00352 325205 326017 - hypothetical protein gene gene351 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00352 S100027_00353 S100027_00353 znuC znuC 326014 326901 - Arabinose import ATP-binding protein AraG ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Repeat%3B Sugar transport%3B Transport%3B Part of the ABC transporter complex AraFGH involved in arabinose import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Arabinose importer (TC 3. A. 1. 2. 2) family%3B Contains 2 ABC transporter domains%3B KEGG: eco:b1858 zinc transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene352 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00353 S100027_00354 S100027_00354 S100027_00354 327051 327638 + Fatty acid metabolism regulator protein Cytoplasm%3B DNA-binding%3B Fatty acid metabolism%3B Lipid degradation%3B Lipid metabolism%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation%2C including acdA%2C fadA%2C fadB%2C fadE%2C fadF%2C fadG%2C fadH%2C fadM%2C fadN%2C lcfA and lcfB. Binding of FadR to DNA is specifically inhibited by long chain fatty acyl-CoA compounds of 14-20 carbon atoms in length%3B Contains 1 HTH tetR-type DNA-binding domain gene gene353 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00354 S100027_00355 S100027_00355 S100027_00355 327741 329636 + hypothetical protein gene gene354 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00355 S100027_00356 S100027_00356 S100027_00356 329668 330150 - hypothetical protein gene gene355 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00356 S100027_00357 S100027_00357 S100027_00357 330143 330706 - Negative transcription regulator PadR Cytoplasm%3B Repressor%3B Transcription%3B Transcription regulation%3B Negative transcriptional regulator of padC phenolic acid decarboxylase gene gene356 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00357 S100027_00358 S100027_00358 S100027_00358 331023 331625 + General stress protein 16U Stress response%3B Belongs to the CAPAB/TerDEXZ family gene gene357 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00358 S100027_00359 S100027_00359 S100027_00359 331654 332235 + General stress protein 16U Stress response%3B Belongs to the CAPAB/TerDEXZ family gene gene358 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00359 S100027_00360 S100027_00360 S100027_00360 332311 332889 + uncharacterized protein Belongs to the CAPAB/TerDEXZ family gene gene359 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00360 S100027_00361 S100027_00361 S100027_00361 332955 333728 + putative membrane protein YceF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the TerC family gene gene360 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00361 S100027_00362 S100027_00362 S100027_00362 333822 335003 + hypothetical protein gene gene361 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00362 S100027_00363 S100027_00363 S100027_00363 335148 335369 + hypothetical protein gene gene362 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00363 S100027_00364 S100027_00364 S100027_00364 335375 336979 + uncharacterized protein gene gene363 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00364 S100027_00365 S100027_00365 S100027_00365 336996 338090 + uncharacterized protein Belongs to the TelA family gene gene364 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00365 S100027_00366 S100027_00366 S100027_00366 338241 338942 + Cytochrome c-type bioproteinis protein CcdA Cell membrane%3B Cytochrome c-type biogenesis%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane%2C promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat%3B Cytochrome c oxidase activity is partially restored by mutations in bdbC or bdbD that are defective in the synthesis of disulfide bond containing proteins. The same mutations abrogate the need for CcdA in sporulation%3B Belongs to the DsbD family gene gene365 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00366 S100027_00367 S100027_00367 S100027_00367 338962 339648 - hypothetical protein gene gene366 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00367 S100027_00368 S100027_00368 S100027_00368 339732 340472 + HTH-type transcriptional regulator ZntR like protein DNA-binding%3B Transcription%3B Transcription regulation%3B Transcriptional regulator%3B Contains 1 HTH merR-type DNA-binding domain gene gene367 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00368 S100027_00369 S100027_00369 S100027_00369 340572 341777 - Nitrate transporter Cell membrane%3B Membrane%3B Nitrate assimilation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B May function as a nitrate transporter%3B Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2. A. 1. 8) family gene gene368 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00369 S100027_00370 S100027_00370 S100027_00370 342227 343186 + L-lactate dehydrogenase Cytoplasm%3B NAD%3B Oxidoreductase%3B Phosphoprotein%3B Belongs to the LDH/MDH superfamily. LDH family%3B KEGG: bli:BL01703 L-lactate dehydrogenase gene gene369 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00370 S100027_00371 S100027_00371 S100027_00371 343236 344858 + L-lactate permease Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B May play a role in L-lactate transport. Belongs to the lactate permease family gene gene370 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00371 S100027_00372 S100027_00372 S100027_00372 344965 345606 + Putative amino acid efflux protein YcgF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the rht family gene gene371 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00372 S100027_00373 S100027_00373 S100027_00373 345607 346935 - putative transporter YcgH Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene372 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00373 S100027_00374 S100027_00374 nadE nadE 347101 347919 + NAD(+) synthase ATP-binding%3B Ligase%3B NAD%3B Nucleotide-binding%3B Belongs to the NAD synthetase family%3B KEGG: bsu:BSU03130 NAD+ synthase gene gene373 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00374 S100027_00375 S100027_00375 aroK aroK 348042 348575 + Shikimate kinase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B ATP-binding%3B Cytoplasm%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Transferase%3B Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate%3B Belongs to the shikimate kinase family%3B KEGG: rpa:RPA0504 shikimate kinase gene gene374 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00375 S100027_00376 S100027_00376 S100027_00376 348867 349637 + uncharacterized protein Coiled coil. gene gene375 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00376 S100027_00377 S100027_00377 S100027_00377 349987 350904 + Proline dehydrogenase FAD%3B Flavoprotein%3B Oxidoreductase%3B Proline metabolism%3B Catalyzes the oxidation of L-proline to delta-1- pyrroline-5-carboxylate (P5C)%3B Belongs to the proline dehydrogenase family%3B KEGG: bsl:A7A1_1878 proline dehydrogenase%3B Acting on the CH-NH group of donors gene gene376 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00377 S100027_00378 S100027_00378 S100027_00378 350928 352478 + L-glutamate gamma-semialdehyde dehydrogenase NAD%3B Oxidoreductase%3B Belongs to the aldehyde dehydrogenase family. RocA subfamily%3B KEGG: bli:BL01710 1-pyrroline-5-carboxylate dehydrogenase gene gene377 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00378 S100027_00379 S100027_00379 S100027_00379 352633 354057 + Sodium/proline symporter Amino-acid transport%3B Cell inner membrane%3B Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Catalyzes the sodium-dependent uptake of extracellular L-proline. This protein is also capable of using lithium as the transport cation. Also catalyzes the uptake of propionate%3B Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene378 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00379 S100027_00380 S100027_00380 S100027_00380 354218 355462 + Proline-responsive transcriptional activator PutR Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Activates transcription of the putBCP operon. Requires proline as a coactivator%3B Belongs to the CdaR family gene gene379 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00380 S100027_00381 S100027_00381 S100027_00381 355500 356345 - UPF0703 protein YcgQ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0703 family gene gene380 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00381 S100027_00382 S100027_00382 S100027_00382 356350 357237 - UPF0718 protein YcgR Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0718 family gene gene381 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00382 S100027_00383 S100027_00383 S100027_00383 357427 358383 + Cephalosporin-C deacetylase Carbohydrate metabolism%3B Cellulose degradation%3B Cytoplasm%3B Hydrolase%3B Polysaccharide degradation%3B Serine esterase%3B Esterase that removed acetyl groups from a number of O- acetylated small substrates%2C such as acetylated xylose%2C short xylooligosaccharides and cephalosporin C. Has no activity towards polymeric acetylated xylan. Cannot cleave amide linkages%3B Belongs to the carbohydrate esterase 7 family%3B KEGG: bli:BL01713 cephalosporin-C deacetylase gene gene382 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00383 S100027_00384 S100027_00384 S100027_00384 358476 358898 + hypothetical protein gene gene383 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00384 S100027_00385 S100027_00385 S100027_00385 358889 359230 + hypothetical protein gene gene384 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00385 S100027_00386 S100027_00386 S100027_00386 359334 359894 - hypothetical protein gene gene385 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00386 S100027_00387 S100027_00387 S100027_00387 360197 360880 - putative amino-acid ABC transporter permease protein YckA Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene386 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00387 S100027_00388 S100027_00388 S100027_00388 360892 361767 - putative ABC transporter extracellular-binding protein YckB Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B Probably part of a binding-protein-dependent transport system. Belongs to the bacterial solute-binding protein 3 family gene gene387 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00388 S100027_00389 S100027_00389 S100027_00389 361951 362502 + Modulator of drug activity B like protein To E. coli MadB and S. pombe SPAC5H10. 05c gene gene388 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00389 S100027_00390 S100027_00390 S100027_00390 362599 363324 + hypothetical protein gene gene389 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00390 S100027_00391 S100027_00391 bglA bglA 363394 364830 + 6-phospho-beta-glucosidase Disulfide bond%3B Glycoprotein%3B Glycosidase%3B Hydrolase%3B Signal%3B Hydrolyzes p-nitrophenyl beta-D-glucoside%2C p-nitrophenyl beta-D-mannoside%2C p-nitrophenyl beta-D-galactoside%2C p-nitrophenyl beta-D-xyloside%2C p-nitrophenyl beta-D-fucoside%2C p-nitrophenyl beta-L-arabinoside%2C cello-oligosaccharides%2C laminari- oligosaccharides and sophorose%3B Belongs to the glycosyl hydrolase 1 family%3B KEGG: bli:BL01718 6-phospho-beta-glucosidase gene gene390 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00391 S100027_00392 S100027_00392 S100027_00392 364869 365267 - DNA-entry nuclease inhibitor Cell membrane%3B Competence%3B Membrane. gene gene391 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00392 S100027_00393 S100027_00393 S100027_00393 365285 365731 - DNA-entry nuclease Cell membrane%3B Competence%3B Hydrolase%3B Manganese%3B Membrane%3B Nuclease%3B Transmembrane%3B Transmembrane helix%3B By degrading DNA that enters the cell%2C plays a role in the competence of cells to be transformed. Degrades both double- stranded%2C linear and covalently closed circular DNA. To B. subtilis NucB gene gene392 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00393 S100027_00394 S100027_00394 S100027_00394 366206 367009 + Non-specific serine/threonine protein kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Serine/threonine-protein kinase%3B Transferase%3B Belongs to the protein kinase superfamily. Ser/Thr protein kinase family%3B Contains 1 protein kinase domain%3B KEGG: bli:BL01719 serine/threonine protein kinase%2C bacterial gene gene393 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00394 S100027_00395 S100027_00395 S100027_00395 367029 367532 - Transducer protein Car Chemotaxis%3B Cytoplasm%3B Methylation%3B Plasmid%3B Transducer%3B Mediates chemotaxis towards arginine. Probably transduces the signal to the histidine kinase CheA%3B Contains 1 methyl-accepting transducer domain%3B Contains 1 PAS (PER-ARNT-SIM) domain gene gene394 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00395 S100027_00396 S100027_00396 S100027_00396 367529 368707 - Methyl-accepting chemotaxis protein TlpC Cell membrane%3B Chemotaxis%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene395 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00396 S100027_00397 S100027_00397 S100027_00397 368829 369569 - Ribonuclease YobL Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 449-600) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YobK%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene396 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00397 S100027_00398 S100027_00398 hyuA hyuA 369974 372028 + N-methylhydantoinase (ATP-hydrolyzing) Belongs to the oxoprolinase family%3B KEGG: bli:BL01720 N-methylhydantoinase A gene gene397 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00398 S100027_00399 S100027_00399 hyuB hyuB 372031 374025 + N-methylhydantoinase (ATP-hydrolyzing) ATP-binding%3B Cytoplasm%3B Hydrolase%3B Nucleotide-binding%3B Catalyzes the cleavage of 5-oxo-L-proline to form L- glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. Acts in the glutathione degradation pathway%3B Belongs to the oxoprolinase family%3B KEGG: bli:BL01721 N-methylhydantoinase B gene gene398 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00399 S100027_00400 S100027_00400 S100027_00400 374022 375110 + hypothetical protein gene gene399 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00400 S100027_00401 S100027_00401 pstB pstB 375111 376238 + Phosphate-transporting ATPase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the ABC transporter superfamily. MsbA family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain%3B KEGG: hde:HDEF_2253 phosphate transport system ATP-binding protein gene gene400 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00401 S100027_00402 S100027_00402 S100027_00402 376225 377091 + Inner membrane ABC transporter permease protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably part of the binding-protein-dependent transport system YdcSTU%3B probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene401 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00402 S100027_00403 S100027_00403 S100027_00403 377084 377896 + Inner membrane ABC transporter permease protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably part of the binding-protein-dependent transport system YdcSTU%3B probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene402 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00403 S100027_00404 S100027_00404 S100027_00404 378634 389382 + Surfactin synthase subunit Antibiotic biosynthesis%3B Ligase%3B Multifunctional enzyme%3B Phosphopantetheine%3B Phosphoprotein%3B Repeat%3B Sporulation%3B This protein is a multifunctional enzyme able to activate and polymerize the amino acids Leu%2C Glu%2C Asp and Val. Activation sites for these AA consist of individual domains. Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 3 acyl carrier domains gene gene403 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00404 S100027_00405 S100027_00405 S100027_00405 389402 400168 + Bacitracin synthase Antibiotic biosynthesis%3B ATP-binding%3B Hydrolase%3B Isomerase%3B Ligase%3B Multifunctional enzyme%3B Nucleotide-binding%3B Phosphopantetheine%3B Phosphoprotein%3B Repeat%3B Induces peptide synthesis%2C activates and incorporates five amino acids%2C forms a thiazoline ring between the first two amino acids and incoporates a D-glutamine in the fourth position. Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 5 acyl carrier domains gene gene404 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00405 S100027_00406 S100027_00406 S100027_00406 400226 404074 + Gramicidin S synthase Antibiotic biosynthesis%3B Hydrolase%3B Ligase%3B Multifunctional enzyme%3B Phosphopantetheine%3B Phosphoprotein%3B Repeat%3B This protein is a multifunctional enzyme%2C able to activate and polymerize the amino acids Pro%2C Val%2C Orn and Leu. Activation sites for these AA consist of individual domains. Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 4 acyl carrier domains gene gene405 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00406 S100027_00407 S100027_00407 S100027_00407 404078 404818 + Surfactin synthase thioesterase subunit Antibiotic biosynthesis%3B Cytoplasm%3B Hydrolase%3B Sporulation%3B Stress response%3B Probable thioesterase involved in the biosynthesis of surfactin. Belongs to the thioesterase family gene gene406 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00407 S100027_00408 S100027_00408 S100027_00408 404865 405776 - putative transporter YcxC Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene407 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00408 S100027_00409 S100027_00409 S100027_00409 405912 407261 + putative HTH-type transcriptional regulator YcxD Aminotransferase%3B DNA-binding%3B Pyridoxal phosphate%3B Transcription%3B Transcription regulation%3B Transferase%3B In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene408 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00409 S100027_00410 S100027_00410 lys5 lys5 407273 407953 - 4'-phosphopantetheinyl transferase Antibiotic biosynthesis%3B Magnesium%3B Metal-binding%3B Transferase%3B May activate the peptidyl carrier protein (PCP) domains of surfactin synthetase SRF1/2/3 and iturin A synthetase%2C by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue. Required for the coproduction of the lipopeptide antibiotics%2C iturin A and surfactin. Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family%3B KEGG: bli:BL01825 4'-phosphopantetheinyl transferase%3B Transferases for other substituted phosphate groups gene gene409 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00410 S100027_00411 S100027_00411 S100027_00411 408023 408838 + uncharacterized protein gene gene410 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00411 S100027_00412 S100027_00412 S100027_00412 409249 409467 + hypothetical protein gene gene411 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00412 S100027_00413 S100027_00413 S100027_00413 409751 410413 - putative membrane protein YczE Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene412 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00413 S100027_00414 S100027_00414 S100027_00414 410669 411199 + hypothetical protein gene gene413 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00414 S100027_00415 S100027_00415 S100027_00415 411226 412155 + Aliphatic sulfonates import ATP-binding protein SsuB ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3. A. 1. 17. 2) family%3B Contains 1 ABC transporter domain gene gene414 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00415 S100027_00416 S100027_00416 S100027_00416 412136 413035 + hypothetical protein gene gene415 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00416 S100027_00417 S100027_00417 S100027_00417 413054 413227 + hypothetical protein gene gene416 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00417 S100027_00418 S100027_00418 S100027_00418 413268 413450 - hypothetical protein gene gene417 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00418 S100027_00419 S100027_00419 S100027_00419 413753 415414 + Aromatic-L-amino-acid decarboxylase Decarboxylase%3B Lyase%3B Neurotransmitter biosynthesis%3B Phosphoprotein%3B Pyridoxal phosphate%3B Catalyzes the production of GABA%3B Belongs to the group II decarboxylase family%3B KEGG: rxy:Rxyl_1038 aromatic-L-amino-acid decarboxylase gene gene418 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00419 S100027_00420 S100027_00420 S100027_00420 415429 417153 + putative methyl-accepting chemotaxis protein Cell membrane%3B Chemotaxis%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene419 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00420 S100027_00421 S100027_00421 S100027_00421 417192 417935 - Galactose/methyl galactoside import ATP-binding protein MglA ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Repeat%3B Sugar transport%3B Transport%3B Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system (Probable)%3B Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3. A. 1. 2. 3) family%3B Contains 2 ABC transporter domains gene gene420 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00421 S100027_00422 S100027_00422 S100027_00422 417951 418655 - L-cystine transport system permease protein TcyB Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex TcyABC involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable)%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene421 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00422 S100027_00423 S100027_00423 S100027_00423 418642 419448 - L-cystine-binding protein TcyA Amino-acid transport%3B Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B Part of the ABC transporter complex TcyABC involved in L-cystine import%3B Belongs to the bacterial solute-binding protein 3 family gene gene422 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00423 S100027_00424 S100027_00424 S100027_00424 419577 420989 - Arginine utilization regulatory protein RocR Activator%3B Arginine metabolism%3B ATP-binding%3B DNA-binding%3B Nucleotide-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Positive regulator of arginine catabolism. Controls the transcription of the two operons rocABC and rocDEF and probably acts by binding to the corresponding upstream activating sequences%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B Contains 1 sigma-54 factor interaction domain gene gene423 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00424 S100027_00425 S100027_00425 rocD rocD 421231 422433 + Ornithine aminotransferase Amino-acid biosynthesis%3B Aminotransferase%3B Cytoplasm%3B Proline biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Catalyzes the interconversion of ornithine to glutamate semialdehyde%3B Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily%3B KEGG: bli:BL01737 ornithine--oxo-acid transaminase gene gene424 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00425 S100027_00426 S100027_00426 S100027_00426 422605 424050 + putative amino acid permease YvbW Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B May participate in leucine metabolism. May transport leucine or a compound related to leucine metabolism%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene425 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00426 S100027_00427 S100027_00427 S100027_00427 424043 424936 + Arginase Arginine metabolism%3B Hydrolase%3B Manganese%3B Metal-binding%3B Belongs to the arginase family%3B KEGG: aka:TKWG_24915 arginase gene gene426 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00427 S100027_00428 S100027_00428 S100027_00428 425005 425877 - HTH-type transcriptional regulator BsdA Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Could be a positive regulator of bsdBCD expression in response to salicylic acid%3B Contains 1 HTH lysR-type DNA-binding domain gene gene427 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00428 S100027_00429 S100027_00429 ubiX ubiX 426000 426569 + 4-hydroxy-3-polyprenylbenzoate decarboxylase Detoxification%3B Flavoprotein%3B FMN%3B Prenyltransferase%3B Transferase%3B Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for phenolic acid decarboxylase C (By similarity). Involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions (PubMed:18388975)%3B Belongs to the UbiX/PAD1 family. YclB subfamily%3B KEGG: eas:Entas_1524 4-hydroxy-3-polyprenylbenzoate decarboxylase gene gene428 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00429 S100027_00430 S100027_00430 ubiD ubiD 426583 428004 + 4-hydroxy-3-polyprenylbenzoate decarboxylase Aromatic hydrocarbons catabolism%3B Decarboxylase%3B Detoxification%3B Lyase%3B Manganese%3B Metal-binding%3B Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate%2C vanillate and salicylate. Is not active on di- and tri-hydroxybenzoate derivatives%3B Belongs to the UbiD family. YclC subfamily%3B KEGG: sul:SYO3AOP1_0556 4-hydroxy-3-polyprenylbenzoate decarboxylase gene gene429 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00430 S100027_00431 S100027_00431 S100027_00431 428024 428251 + Phenolic acid decarboxylase subunit Aromatic hydrocarbons catabolism%3B Decarboxylase%3B Detoxification%3B Lyase%3B Part of the BsdBCD complex involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate%2C vanillate and salicylate. Is not active on di- and tri-hydroxybenzoate derivatives gene gene430 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00431 S100027_00432 S100027_00432 S100027_00432 428267 428722 + uncharacterized protein gene gene431 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00432 S100027_00433 S100027_00433 S100027_00433 428757 429203 - hypothetical protein gene gene432 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00433 S100027_00434 S100027_00434 S100027_00434 429229 429570 - hypothetical protein gene gene433 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00434 S100027_00435 S100027_00435 S100027_00435 429628 430074 - hypothetical protein gene gene434 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00435 S100027_00436 S100027_00436 S100027_00436 430095 430736 - hypothetical protein gene gene435 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00436 S100027_00437 S100027_00437 S100027_00437 430754 431011 - hypothetical protein gene gene436 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00437 S100027_00438 S100027_00438 S100027_00438 431177 431980 - hypothetical protein gene gene437 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00438 S100027_00439 S100027_00439 S100027_00439 432006 432347 - hypothetical protein gene gene438 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00439 S100027_00440 S100027_00440 S100027_00440 432360 433985 - Ribonuclease YxiD Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene439 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00440 S100027_00441 S100027_00441 S100027_00441 434003 434281 - uncharacterized protein gene gene440 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00441 S100027_00442 S100027_00442 S100027_00442 434295 434678 - uncharacterized protein gene gene441 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00442 S100027_00443 S100027_00443 S100027_00443 435180 436172 + D-allose-binding periplasmic protein Periplasm%3B Signal%3B Sugar transport%3B Transport%3B Part of the binding-protein-dependent transport system AlsBAC for D-allose%3B Belongs to the bacterial solute-binding protein 2 family gene gene442 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00443 S100027_00444 S100027_00444 yesM yesM 436159 437928 + Histidine kinase Cell membrane%3B Chemotaxis%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpB is required for taxis towards asparagine%2C aspartate%2C glutamine%2C and histidine%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain%3B KEGG: bli:BL01744 two-component system%2C sensor histidine kinase YesM gene gene443 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00444 S100027_00445 S100027_00445 S100027_00445 437921 439123 + putative response regulatory protein Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Probable member of the two-component regulatory system SAB0162c/SAB0161c%3B Contains 1 HTH araC/xylS-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene444 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00445 S100027_00446 S100027_00446 S100027_00446 439251 440330 + Multiple sugar-binding periplasmic receptor ChvE Chemotaxis%3B Crown gall tumor%3B Periplasm%3B Signal%3B Required for effective transcriptional induction of the vir genes by monosaccharides in response to plant signals and for normal growth and chemotaxis towards certain sugars. Function as a periplasmic multiple sugar-binding receptor protein. It does not interact with a transport system. Belongs to the bacterial solute-binding protein 2 family gene gene445 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00446 S100027_00447 S100027_00447 S100027_00447 440335 441903 + L-arabinose transport ATP-binding protein AraG ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Repeat%3B Sugar transport%3B Transport%3B Part of the binding-protein-dependent transport system for L-arabinose. Probably responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 2 ABC transporter domains gene gene446 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00447 S100027_00448 S100027_00448 S100027_00448 441878 443089 + Xylose transport system permease protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily gene gene447 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00448 S100027_00449 S100027_00449 S100027_00449 443136 444404 - putative MFS-type transporter YbfB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene448 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00449 S100027_00450 S100027_00450 yjgM yjgM 444420 445337 - Putative HTH-type DNA-binding domain-containing acetyltransferase YbfA Acyltransferase%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Transferase%3B Putative DNA-binding acetyltransferase%3B Contains 1 HTH marR-type DNA-binding domain%3B Contains 1 N-acetyltransferase domain%3B KEGG: bfb:VU15_08170 putative acetyltransferase%3B Transferring groups other than amino-acyl groups gene gene449 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00450 S100027_00451 S100027_00451 bgaB bgaB 445618 447690 + Beta-galactosidase Glycosidase%3B Hydrolase%3B Metal-binding%3B Zinc%3B Belongs to the glycosyl hydrolase 42 family%3B KEGG: bli:BL01749 beta-galactosidase gene gene450 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00451 S100027_00452 S100027_00452 S100027_00452 447925 449070 - 3-phytase Hydrolase%3B Secreted%3B Signal%3B Catalyzes the hydrolysis of inorganic orthophosphate from phytate. Only phytate%2C ADP%2C and ATP were hydrolyzed (100%2C 75%2C and 50%25 of the relative activity%2C respectively). Contains 1 BPP (beta-propeller phytase) domain%3B KEGG: bli:BL01844 3-phytase gene gene451 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00452 S100027_00453 S100027_00453 S100027_00453 449321 450811 - putative transporter YclF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the PTR2/POT transporter (TC 2. A. 17) family gene gene452 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00453 S100027_00454 S100027_00454 S100027_00454 451080 452837 + uncharacterized protein Repeat%3B Contains 11 PbH1 repeats gene gene453 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00454 S100027_00455 S100027_00455 S100027_00455 452861 453079 - hypothetical protein gene gene454 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00455 S100027_00456 S100027_00456 S100027_00456 453174 454847 + Spore germination protein KA Cell membrane%3B Germination%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Involved in the germination response to the combination of glucose%2C fructose%2C L-asparagine%2C and KCl. Belongs to the GerABKA family gene gene455 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00456 S100027_00457 S100027_00457 S100027_00457 454831 456054 + Spore germination protein KC Cell membrane%3B Germination%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Involved in the germination response to the combination of glucose%2C fructose%2C L-asparagine%2C and KCl. Belongs to the GerABKC lipoprotein family gene gene456 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00457 S100027_00458 S100027_00458 S100027_00458 456079 457185 + Spore germination protein KB Cell membrane%3B Germination%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the germination response to the combination of glucose%2C fructose%2C L-asparagine%2C and KCl. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2. A. 3. 9) family gene gene457 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00458 S100027_00459 S100027_00459 S100027_00459 457241 457969 + HTH-type transcriptional activator TipA Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Transcriptional activator. Is activated when bound to the antibiotic thiostrepton (By similarity)%3B Contains 1 HTH merR-type DNA-binding domain gene gene458 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00459 S100027_00460 S100027_00460 S100027_00460 458002 458685 - Spermidine/putrescine import ATP-binding protein PotA ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3. A. 1. 11. 1) family%3B Contains 1 ABC transporter domain gene gene459 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00460 S100027_00461 S100027_00461 S100027_00461 458701 460140 - putative ABC transporter permease YclI Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the ABC-4 integral membrane protein family gene gene460 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00461 S100027_00462 S100027_00462 S100027_00462 460358 461044 + Cell cycle transcriptional regulator CtrA DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Forms part of a two-component regulatory system CtrA/CckA that controls multiple events in the cell cycle%2C including cell division%2C stalk synthesis and cell cycle-specific transcription. Binds to a group of cell cycle-regulated promoters critical for DNA replication%2C DNA methylation%2C and class II flagellar biogenesis. Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene461 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00462 S100027_00463 S100027_00463 resE resE 461034 462461 + Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Could be member of the two-component regulatory system YclK/YclJ. Potentially phosphorylates YclJ%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: gst:HW35_03555 two-component system%2C OmpR family%2C sensor histidine kinase ResE gene gene462 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00463 S100027_00464 S100027_00464 S100027_00464 462494 463285 - Methyl-accepting chemotaxis protein McpB Cell membrane%3B Chemotaxis%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpB is required for taxis towards asparagine%2C aspartate%2C glutamine%2C and histidine%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene463 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00464 S100027_00465 S100027_00465 S100027_00465 463300 464199 - Methyl-accepting chemotaxis protein McpA Cell membrane%3B Chemotaxis%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpA is required for taxis towards glucose and alpha-methylglucoside%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene464 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00465 S100027_00466 S100027_00466 lysC lysC 464335 465696 - Aspartate kinase Amino-acid biosynthesis%3B ATP-binding%3B Diaminopimelate biosynthesis%3B Kinase%3B Lysine biosynthesis%3B Nucleotide-binding%3B Repeat%3B Transferase%3B Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate%2C which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine%2C isoleucine and methionine%3B Belongs to the aspartokinase family%3B Contains 2 ACT domains%3B KEGG: bsu:BSU03790 aspartate kinase gene gene465 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00466 S100027_00467 S100027_00467 S100027_00467 465973 466926 + putative ABC transporter permease protein YclN Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably part of an ABC transporter complex. Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene466 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00467 S100027_00468 S100027_00468 S100027_00468 466916 467860 + putative ABC transporter permease protein YclO Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably part of an ABC transporter complex. Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene467 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00468 S100027_00469 S100027_00469 S100027_00469 467860 468618 + Polar-amino-acid-transporting ATPase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Phosphonate transport%3B Transport%3B Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3. A. 1. 9. 1) family%3B Contains 1 ABC transporter domain%3B KEGG: msu:MS1685 polar amino acid transport system ATP-binding protein gene gene468 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00469 S100027_00470 S100027_00470 S100027_00470 468633 469580 + Putative ABC transporter substrate-binding lipoprotein YhfQ Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene469 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00470 S100027_00471 S100027_00471 S100027_00471 469749 471170 - MFS antiporter QDR2 Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Virulence%3B MFS antiporter that does not display functional linkage as drug transporter and performs functions that significantly affect biofilm development and virulence. No substrate for transport has been identified yet%2C but plays an important role in the growth in the host%3B Belongs to the major facilitator superfamily. CAR1 family gene gene470 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00471 S100027_00472 S100027_00472 S100027_00472 471182 472069 - putative HTH-type transcriptional regulator YcnC DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH tetR-type DNA-binding domain gene gene471 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00472 S100027_00473 S100027_00473 S100027_00473 472164 473006 - Carboxyvinyl-carboxyphosphonate phosphorylmutase KEGG: sen:SACE_4109 carboxyvinyl-carboxyphosphonate phosphorylmutase gene gene472 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00473 S100027_00474 S100027_00474 S100027_00474 473117 473854 - FMN reductase (NAD(P)H) Aromatic hydrocarbons catabolism%3B Detoxification%3B Flavoprotein%3B FMN%3B NAD%3B Oxidoreductase%3B Reduces FMNH(2) to FMN%2C with NADH or NADPH as reductant. It also reduces nitroaromatic compounds%2C quinones%2C chromates and azo dyes. It could supply the reduced form of FMN to luciferase- like protein and contribute to the degradation of aromatic compounds%3B Belongs to the flavin oxidoreductase frp family%3B KEGG: bsu:BSU03860 FMN reductase (NAD(P)H) gene gene473 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00474 S100027_00475 S100027_00475 S100027_00475 473873 474160 - Putative monooxygenase YcnE Aromatic hydrocarbons catabolism%3B Detoxification%3B Monooxygenase%3B Oxidoreductase%3B Phosphoprotein%3B Putative monooxygenase that may contribute to the degradation of aromatic compounds%3B Belongs to the LsrG family%3B Contains 1 ABM domain gene gene474 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00475 S100027_00476 S100027_00476 S100027_00476 474338 474634 + putative HTH-type transcriptional regulator YczG DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH arsR-type DNA-binding domain gene gene475 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00476 S100027_00477 S100027_00477 S100027_00477 474699 476129 - HTH-type transcriptional regulatory protein GabR Activator%3B Aminotransferase%3B DNA-binding%3B Pyridoxal phosphate%3B Repressor%3B Transcription%3B Transcription regulation%3B Transferase%3B Activates the transcription of the gabTD operon. Is also a repressor of its own expression%2C both in the presence and absence of GABA. Binds specifically to the DNA region overlapping the -35 region of the gabT promoter and the -10 and +1 regions of the gabR promoter. Principally regulates the utilization of gamma- aminobutyrate%3B In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene476 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00477 S100027_00478 S100027_00478 gabT gabT 476232 477545 + 4-aminobutyrate--2-oxoglutarate transaminase Aminotransferase%3B Pyridoxal phosphate%3B Transferase%3B Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bli:BL01762 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase gene gene477 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00478 S100027_00479 S100027_00479 S100027_00479 477579 478970 + Amino-acid permease RocE Amino-acid transport%3B Arginine metabolism%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Putative transport protein involved in arginine degradative pathway. Probably transports arginine or ornithine. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2. A. 3. 1) family gene gene478 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00479 S100027_00480 S100027_00480 gabD gabD 478945 480339 + Succinate-semialdehyde dehydrogenase (NAD(P)(+)) Cytoplasm%3B NAD%3B Oxidoreductase%3B Converts 9-cis-retinal to 9-cis-retinoic acid. Has lower activity towards 13-cis-retinal. Has much lower activity towards all-trans-retinal. Has highest activity with benzaldehyde and decanal (in vitro). Has a preference for NAD%2C but shows considerable activity with NADP (in vitro) (By similarity)%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: bli:BL01765 succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase gene gene479 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00480 S100027_00481 S100027_00481 S100027_00481 480386 481270 - putative transporter YwfM Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene480 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00481 S100027_00482 S100027_00482 S100027_00482 481435 481926 + hypothetical protein gene gene481 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00482 S100027_00483 S100027_00483 S100027_00483 481974 482618 - uncharacterized protein Cell membrane%3B Membrane%3B Signal%3B Transmembrane%3B Transmembrane helix. gene gene482 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00483 S100027_00484 S100027_00484 S100027_00484 482621 484258 - Copper transport protein YcnJ Cell membrane%3B Copper%3B Copper transport%3B Ion transport%3B Membrane%3B Metal-binding%3B Signal%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in uptake of extracellular oxidized copper under copper-limiting conditions%3B In the N-terminal sectio%3B belongs to the CopC family%3B In the C-terminal sectio%3B belongs to the CopD family gene gene483 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00484 S100027_00485 S100027_00485 S100027_00485 484287 484859 - putative HTH-type transcriptional regulator YgbI DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH deoR-type DNA-binding domain gene gene484 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00485 S100027_00486 S100027_00486 nirB nirB 485120 487414 + Nitrite reductase (NADH) Electron transport%3B FAD%3B Flavoprotein%3B NADP%3B Nitrate assimilation%3B Transport%3B Required for nitrate assimilation%3B KEGG: mmt:Metme_3418 nitrite reductase (NADH) large subunit gene gene485 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00486 S100027_00487 S100027_00487 nasA nasA 487416 489575 + Nitrate reductase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Molybdenum%3B Nitrate assimilation%3B Oxidoreductase%3B Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants%2C fungi and bacteria. Belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: bsu:BSU03310 assimilatory nitrate reductase catalytic subunit gene gene486 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00487 S100027_00488 S100027_00488 S100027_00488 489689 492109 + Nitrite reductase (NADH) 4Fe-4S%3B FAD%3B Flavoprotein%3B Heme%3B Iron%3B Iron-sulfur%3B Metal-binding%3B NADP%3B Nitrate assimilation%3B Oxidoreductase%3B Required for nitrite assimilation%3B Belongs to the nitrite and sulfite reductase 4Fe-4S domain family%3B KEGG: bsu:BSU03300 nitrite reductase (NADH) large subunit gene gene487 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00488 S100027_00489 S100027_00489 nirD nirD 492140 492460 + Nitrite reductase (NADH) 2Fe-2S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B NAD%3B Nitrate assimilation%3B Oxidoreductase%3B Required for nitrite assimilation. Required for activity of the reductase (By similarity)%3B Contains 1 Rieske domain%3B KEGG: bsu:BSU03290 nitrite reductase (NADH) small subunit gene gene488 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00489 S100027_00490 S100027_00490 S100027_00490 492578 494038 + Uroporphyrinogen-III C-methyltransferase Methyltransferase%3B Porphyrin biosynthesis%3B S-adenosyl-L-methionine%3B Transferase%3B Belongs to the precorrin methyltransferase family%3B KEGG: bli:BL01771 uroporphyrinogen III methyltransferase / synthase gene gene489 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00490 S100027_00491 S100027_00491 S100027_00491 494064 494744 - HTH-type transcriptional repressor CsiR Cytoplasm%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Modulates expression of csiD and lhgO in a temporal manner during entry into stationary phase or during the first few hours of carbon starvation%3B Contains 1 HTH gntR-type DNA-binding domain gene gene490 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00491 S100027_00492 S100027_00492 S100027_00492 494973 496613 + Sodium-dependent dicarboxylate transporter SdcS Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mediates the transport of the dicarboxylates fumarate%2C malate%2C and succinate across the cytoplasmic membrane via a Na(+)- electrochemical gradient%3B Belongs to the SLC13A/DASS transporter (TC 2. A. 47) family. NADC subfamily gene gene491 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00492 S100027_00493 S100027_00493 fabZ fabZ 496702 496887 + 3-hydroxyacyl-[acyl-carrier-protein] dehydratase Belongs to the thioester dehydratase family. FabZ subfamily%3B KEGG: bamt:AJ82_02350 3-hydroxyacyl-(acyl-carrier-protein) dehydratase gene gene492 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00493 S100027_00494 S100027_00494 fwdE fwdE 497141 497608 + Formylmethanofuran dehydrogenase Alternative splicing%3B Hydrolase%3B Hydrolyzes acyl-CoA thioesters (in vitro). Has a preference for substrates with medium chain length (C10-C14). Inactive towards substrates with C18 or C20 aliphatic chains. Its physiological substrate is not known (By similarity)%3B Contains 1 TsaA-like domain%3B KEGG: aar:Acear_0784 formylmethanofuran dehydrogenase subunit E gene gene493 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00494 S100027_00495 S100027_00495 ulaC ulaC 497774 499825 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cytoplasm%3B Kinase%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in mannitol transport (By similarity)%3B Contains 1 PTS EIIA type-2 domain%3B KEGG: bcl:ABC0945 PTS system%2C ascorbate-specific IIA component gene gene494 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00495 S100027_00496 S100027_00496 ulaB ulaB 499842 500123 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase KEGG: efe:EFER_0867 PTS system%2C ascorbate-specific IIB component gene gene495 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00496 S100027_00497 S100027_00497 S100027_00497 500147 501520 + Ascorbate-specific permease IIC component UlaA Cell inner membrane%3B Cell membrane%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active- transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in ascorbate transport (By similarity)%3B Belongs to the UlaA family gene gene496 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00497 S100027_00498 S100027_00498 tktA tktA 501535 502377 + Transketolase Calcium%3B Magnesium%3B Metal-binding%3B Thiamine pyrophosphate%3B Transferase%3B Plays an essential role in total transketolase activity and cell proliferation in cancer cell%3B after transfection with anti-TKTL1 siRNA%2C total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells. Plays a pivotal role in carcinogenesis (By similarity)%3B Belongs to the transketolase family%3B KEGG: bli:BL01777 transketolase%3B overlaps another CDS with the same product name gene gene497 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00498 S100027_00499 S100027_00499 S100027_00499 502374 503324 + Transketolase Isoprene biosynthesis%3B Magnesium%3B Metal-binding%3B Thiamine biosynthesis%3B Thiamine pyrophosphate%3B Transferase%3B Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)%3B Belongs to the transketolase family. DXPS subfamily%3B KEGG: bli:BL05028 transketolase%3B overlaps another CDS with the same product name gene gene498 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00499 S100027_00500 S100027_00500 S100027_00500 503399 504154 + Putative phosphatase YcsE Hydrolase%3B Magnesium%3B Metal-binding%3B Belongs to the HAD-like hydrolase superfamily. Cof family gene gene499 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00500 S100027_00501 S100027_00501 S100027_00501 504441 505202 + UPF0271 protein Belongs to the UPF0271 (lamB) family gene gene500 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00501 S100027_00502 S100027_00502 S100027_00502 505227 506438 + putative membrane protein YcsG Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the NRAMP family gene gene501 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00502 S100027_00503 S100027_00503 S100027_00503 506435 507232 + UPF0317 protein Belongs to the UPF0317 family gene gene502 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00503 S100027_00504 S100027_00504 S100027_00504 507310 508044 + Kinase A inhibitor ATP-binding%3B Nucleotide-binding%3B Protein kinase inhibitor%3B Sporulation%3B Is a potent inhibitor of the autophosphorylation reaction of kinase A and its reverse reaction%2C but does not inhibit phosphate transfer to the Spo0F response regulator once kinase A is phosphorylated. KipI is an inhibitor of the catalytic domain of kinase A affecting the ATP/ADP reactions and not the phosphotransferase functions of this domain. The inhibition is noncompetitive with respect to ATP gene gene503 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00504 S100027_00505 S100027_00505 S100027_00505 508041 509054 + KipI antagonist Sporulation%3B Counteracts the inhibitory action of KipI on sporulation. May bind to KipI%2C preventing its function as an inhibitor of kinase A gene gene504 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00505 S100027_00506 S100027_00506 S100027_00506 509086 509835 + HTH-type transcriptional regulator KipR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcriptional repressor of the kip gene-containing operon%3B Contains 1 HTH iclR-type DNA-binding domain%3B Contains 1 iclR-ED (iclR effector binding) domain gene gene505 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00506 S100027_00507 S100027_00507 S100027_00507 509924 510562 + Spore germination lipase LipC Hydrolase%3B Sporulation%3B Lipase involved in spore germination%3B Belongs to the 'GDSL' lipolytic enzyme family gene gene506 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00507 S100027_00508 S100027_00508 mtlA mtlA 510807 512231 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Kinase%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in mannitol transport (By similarity)%3B Contains 1 PTS EIIB type-2 domain%3B Contains 1 PTS EIIC type-2 domain%3B KEGG: bld:BLi00505 PTS system%2C mannitol-specific IIB component gene gene507 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00508 S100027_00509 S100027_00509 S100027_00509 512298 512738 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Kinase%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in mannitol transport (By similarity)%3B Contains 1 PTS EIIA type-2 domain%3B Contains 1 PTS EIIB type-2 domain%3B Contains 1 PTS EIIC type-2 domain%3B KEGG: bld:BLi00506 PTS system%2C mannitol-specific IIA component gene gene508 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00509 S100027_00510 S100027_00510 mtlD mtlD 512735 513874 + Mannitol-1-phosphate 5-dehydrogenase NAD%3B Oxidoreductase%3B Belongs to the mannitol dehydrogenase family%3B KEGG: eco:b3600 mannitol-1-phosphate 5-dehydrogenase gene gene509 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00510 S100027_00511 S100027_00511 S100027_00511 514155 516233 + Transcriptional regulator MtlR Activator%3B DNA-binding%3B Kinase%3B Phosphoprotein%3B Repeat%3B Transcription%3B Transcription regulation%3B Transferase%3B Positively regulates the expression of the mtlAFD operon involved in the uptake and catabolism of mannitol%3B Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains%3B Contains 1 PTS EIIA type-2 domain%3B Contains 1 PTS EIIB type-2 domain gene gene510 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00511 S100027_00512 S100027_00512 S100027_00512 516346 517215 + General stress protein 39 Oxidoreductase%3B Stress response%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bli:BL02817 null%3B Oxidoreductases gene gene511 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00512 S100027_00513 S100027_00513 S100027_00513 517231 517734 + putative D-lyxose ketol-isomerase Carbohydrate metabolism%3B Isomerase%3B Manganese%3B Metal-binding%3B Belongs to the D-lyxose ketol-isomerase family gene gene512 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00513 S100027_00514 S100027_00514 S100027_00514 517751 518134 - hypothetical protein gene gene513 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00514 S100027_00515 S100027_00515 S100027_00515 518220 518642 + General stress protein Stress response. gene gene514 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00515 S100027_00516 S100027_00516 S100027_00516 519095 519904 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene515 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00516 S100027_00517 S100027_00517 S100027_00517 520069 521010 + Regulatory protein MsrR Cell membrane%3B Membrane%3B Signal-anchor%3B Transcription%3B Transcription regulation%3B Transmembrane%3B Transmembrane helix%3B Involved in SarA attenuation. Affects resistance to oxacillin and teicoplanin%2C as well as the synthesis of virulence factors%3B Belongs to the LytR/CpsA/Psr regulatory protein family gene gene516 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00517 S100027_00518 S100027_00518 S100027_00518 521042 521335 - putative membrane protein YdzA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene517 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00518 S100027_00519 S100027_00519 S100027_00519 521419 521829 - hypothetical protein gene gene518 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00519 S100027_00520 S100027_00520 S100027_00520 521947 522375 + HTH-type transcriptional regulator LrpA DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Negative regulation of glyA transcription and kinB- dependent sporulation%3B Contains 1 HTH asnC-type DNA-binding domain gene gene519 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00520 S100027_00521 S100027_00521 topB topB 522416 524632 + DNA topoisomerase DNA-binding%3B Isomerase%3B Magnesium%3B Metal-binding%3B Topoisomerase%3B Releases the supercoiling and torsional tension of DNA%2C which is introduced during the DNA replication and transcription%2C by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme%2C resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand%2C thus removing DNA supercoils. Finally%2C in the religation step%2C the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone%3B Belongs to the type IA topoisomerase family%3B Contains 1 Toprim domain%3B KEGG: bld:BLi00518 DNA topoisomerase III gene gene520 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00521 S100027_00522 S100027_00522 S100027_00522 525320 526792 + putative amino acid permease YdaO Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene521 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00522 S100027_00523 S100027_00523 S100027_00523 526817 527140 + putative amino acid permease YdaO Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene522 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00523 S100027_00524 S100027_00524 poxL poxL 527248 528969 + Pyruvate oxidase FAD%3B Flavoprotein%3B Magnesium%3B Metal-binding%3B Oxidoreductase%3B Thiamine pyrophosphate%3B Important for the aerobic growth. Decarboxylates pyruvate in four steps. The energy released is partially stored in acetyl phosphate. Belongs to the TPP enzyme family%3B KEGG: bli:BL00146 pyruvate oxidase gene gene523 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00524 S100027_00525 S100027_00525 S100027_00525 529110 529721 + GlcNAc-binding protein Chitin-binding%3B Secreted%3B Signal%3B Probably interacts with GlcNAc residues. May promote attachment to both epithelial cell surfaces and chitin%3B Belongs to the GbpA family%3B Contains 1 chitin-binding type-3 domain%3B Contains 1 chitin-binding type-4 domain gene gene524 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00525 S100027_00526 S100027_00526 S100027_00526 529909 530241 + hypothetical protein gene gene525 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00526 S100027_00527 S100027_00527 S100027_00527 530211 531071 + putative transposase-like protein DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene526 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00527 S100027_00528 S100027_00528 S100027_00528 531136 531387 - putative membrane protein YdzK Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene527 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00528 S100027_00529 S100027_00529 rimL rimL 531459 532010 - Putative ribosomal N-acetyltransferase YdaF Acyltransferase%3B Transferase%3B Putative N-acetyltransferase. May act on ribosomal proteins (Potential)%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bli:BL00141 ribosomal-protein-serine acetyltransferase%3B Transferring groups other than amino-acyl groups gene gene528 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00529 S100027_00530 S100027_00530 S100027_00530 532065 533345 - Divalent metal cation transporter MntH Cell membrane%3B Ion transport%3B Manganese%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B H(+)-stimulated%2C divalent metal cation uptake system. Involved in manganese uptake. Can probably also transport cadmium%2C cobalt%2C copper and zinc%2C but not iron. May be the predominant transporter of manganese during logarithmic phase growth%3B Belongs to the NRAMP family gene gene529 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00530 S100027_00531 S100027_00531 S100027_00531 533528 533776 - UPF0410 protein YdaS Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0410 family gene gene530 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00531 S100027_00532 S100027_00532 aspA aspA 533872 535293 - Aspartate ammonia-lyase Lyase%3B Belongs to the class-II fumarase/aspartase family. Aspartase subfamily%3B KEGG: bli:BL02922 aspartate ammonia-lyase gene gene531 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00532 S100027_00533 S100027_00533 S100027_00533 535602 536786 + putative UDP-glucosyltransferase YdhE Glycosyltransferase%3B Transferase%3B Belongs to the UDP-glycosyltransferase family%3B KEGG: sma:SAV_945 dTDP-L-oleandrosyltransferase%3B Hexosyltransferases gene gene532 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00533 S100027_00534 S100027_00534 S100027_00534 536812 537258 - uncharacterized protein gene gene533 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00534 S100027_00535 S100027_00535 S100027_00535 537377 538201 + uncharacterized protein gene gene534 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00535 S100027_00536 S100027_00536 S100027_00536 538241 539530 - Malate-2H(+)/Na(+)-lactate antiporter Antiport%3B Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Couples proton uptake and Na(+) efflux to the substrate- product malate/lactate antiport%2C in an electroneutral malate- 2H(+)/Na(+)-lactate exchange. Plays a role in supporting growth to high density on malate at reduced protonmotive force. Belongs to the NhaC Na(+)/H(+) (TC 2. A. 35) antiporter family gene gene535 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00536 S100027_00537 S100027_00537 S100027_00537 539659 540375 + uncharacterized protein Belongs to the SchB/CurC family gene gene536 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00537 S100027_00538 S100027_00538 S100027_00538 540450 540890 + Glucose starvation-inducible protein Repeat%3B Stress response. gene gene537 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00538 S100027_00539 S100027_00539 S100027_00539 541112 542152 + UPF0118 membrane protein YdbI Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0118 (PerM) family gene gene538 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00539 S100027_00540 S100027_00540 S100027_00540 542440 543684 + C4-dicarboxylate transport protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Plasmid%3B Sugar transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Responsible for the transport of dicarboxylates such as succinate%2C fumarate%2C and malate from the periplasm across the membrane%3B Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family gene gene539 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00540 S100027_00541 S100027_00541 S100027_00541 543754 544680 + Zinc import ATP-binding protein ZnuC ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Ion transport%3B Membrane%3B Nucleotide-binding%3B Transport%3B Zinc%3B Zinc transport%3B Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Zinc importer (TC 3. A. 1. 15. 5) family%3B Contains 1 ABC transporter domain gene gene540 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00541 S100027_00542 S100027_00542 S100027_00542 544673 545440 + putative membrane protein YdbK Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene541 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00542 S100027_00543 S100027_00543 S100027_00543 545540 545896 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene542 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00543 S100027_00544 S100027_00544 S100027_00544 546021 547169 + Medium-chain acyl-CoA dehydrogenase FAD%3B Flavoprotein%3B Oxidoreductase%3B Belongs to the acyl-CoA dehydrogenase family%3B KEGG: bcz:BCZK2818 acyl-CoA dehydrogenase gene gene543 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00544 S100027_00545 S100027_00545 S100027_00545 547243 547398 - uncharacterized protein gene gene544 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00545 S100027_00546 S100027_00546 S100027_00546 547401 547559 - hypothetical protein gene gene545 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00546 S100027_00547 S100027_00547 S100027_00547 547975 548295 - Thioredoxin Disulfide bond%3B Electron transport%3B Redox-active center%3B Transport%3B Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions%3B Belongs to the thioredoxin family%3B Contains 1 thioredoxin domain gene gene546 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00547 S100027_00548 S100027_00548 S100027_00548 548456 549541 + D-alanine--D-alanine ligase ATP-binding%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Ligase%3B Magnesium%3B Manganese%3B Metal-binding%3B Nucleotide-binding%3B Peptidoglycan synthesis%3B Cell wall formation%3B Belongs to the D-alanine--D-alanine ligase family%3B Contains 1 ATP-grasp domain%3B KEGG: bli:BL02193 D-alanine-D-alanine ligase gene gene547 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00548 S100027_00549 S100027_00549 murF murF 549679 551049 + UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase ATP-binding%3B Cell cycle%3B Cell division%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Peptidoglycan synthesis%3B Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide%2C the precursor of murein%3B Belongs to the MurCDEF family. MurF subfamily%3B KEGG: bli:BL02194 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase gene gene548 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00549 S100027_00550 S100027_00550 yvaK yvaK 551109 551825 + Carboxylesterase KEGG: paa:Paes_2227 carboxylesterase gene gene549 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00550 S100027_00551 S100027_00551 deaD deaD 552176 553639 + RNA helicase ATP-binding%3B Cytoplasm%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B RNA-binding%3B Stress response%3B DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions%2C has RNA- dependent ATPase activity%3B Belongs to the DEAD box helicase family. CshA subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bsu:BSU04580 ATP-dependent RNA helicase DeaD gene gene550 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00551 S100027_00552 S100027_00552 S100027_00552 553753 554232 + UPF0699 transmembrane protein YdbS Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0699 family gene gene551 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00552 S100027_00553 S100027_00553 S100027_00553 554222 555703 + UPF0699 transmembrane protein YdbT Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0699 family gene gene552 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00553 S100027_00554 S100027_00554 S100027_00554 555700 556299 - Putative rhomboid protease YdcA Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Belongs to the peptidase S54 family gene gene553 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00554 S100027_00555 S100027_00555 S100027_00555 556594 557601 + Sporulation protein YdcC Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B required for efficient sporulation gene gene554 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00555 S100027_00556 S100027_00556 S100027_00556 557823 558995 + Alanine racemase Isomerase%3B Pyridoxal phosphate%3B Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids%3B Belongs to the alanine racemase family%3B KEGG: bld:BLi00551 alanine racemase gene gene555 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00556 S100027_00557 S100027_00557 S100027_00557 559107 559388 + Antitoxin EndoAI Antitoxin component of a type II toxin-antitoxin (TA) module. Antitoxin that directly inhibits activity of EndoA in vitro. Upon expression in E. coli counteracts inhibitory effect of endoribonuclease EndoA. The EndoA-EndoAI complex does not seem to bind its own promoter (PubMed:24120662)%3B Belongs to the MazE/EndoAI family gene gene556 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00557 S100027_00558 S100027_00558 mazF mazF 559393 559743 + Endoribonuclease EndoA Endonuclease%3B Hydrolase%3B Nuclease%3B RNA-binding%3B Toxin%3B Toxic component of a type II toxin-antitoxin (TA) module. Specific for 5'-UACAU-3' sequences%2C cleaving after the first U (PubMed:21763692). Yields cleavage products with 3' phosphate and 5' hydroxyl groups (PubMed:15882409). Cannot digest substrate with a UUdUACAUAA cleavage site (PubMed:24120662). Overexpression is toxic for cell growth (shown in E. coli)%2C probably by inhibiting protein synthesis through the cleavage of single-stranded RNA. The toxicity is reversed by the antitoxin EndoAI. Toxin activity cannot be inhibited by MazE from E. coli. The EndoA-EndoAI complex does not seem to bind its own promoter (PubMed:24120662)%3B Belongs to the PemK/MazF family%3B KEGG: bsu:BSU04660 mRNA interferase MazF%3B Acting on ester bonds gene gene557 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00558 S100027_00559 S100027_00559 S100027_00559 559861 560688 + RsbT co-antagonist protein RsbRA Phosphoprotein%3B Acts as a positive regulator of sigma-B activity in response to salt and heat stress by stimulating the activity of the RsbT kinase toward RsbS in vitro. One of 4 functionally non-identical RsbR paralogs%2C it functions in the environmental signaling branch of the general stress response. Negative regulator of sigma-B activity. Non- phosphorylated RsbS binds to RsbT%2C preventing its association with RsbU. Requires any one of RsbRA%2C RsbRB%2C RsbRC or RsbRD to sequester RsbT. When RsbS and the RsbR paralog(s) are phosphorylated%2C they release RsbT%2C which can then bind and activate RsbU. Contains 1 STAS domain gene gene558 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00559 S100027_00560 S100027_00560 S100027_00560 560692 561057 + RsbT antagonist protein RsbS Phosphoprotein%3B Negative regulator of sigma-B activity. Non- phosphorylated RsbS binds to RsbT%2C preventing its association with RsbU. Requires any one of RsbRA%2C RsbRB%2C RsbRC or RsbRD to sequester RsbT. When RsbS and the RsbR paralog(s) are phosphorylated%2C they release RsbT%2C which can then bind and activate RsbU%3B Contains 1 STAS domain gene gene559 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00560 S100027_00561 S100027_00561 rsbT rsbT 561060 561461 + Non-specific serine/threonine protein kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Serine/threonine-protein kinase%3B Transferase%3B Provides the crucial link between the upstream module (communication of environmental stress) and the downstream module (integration of the environmental signals with signals of energy stress) that compose the signal transduction pathway controlling the sigma-B factor. Phosphorylates and inactivates its specific antagonist protein RsbS thanks to its serine kinase activity. Upon phosphorylation of RsbS%2C RsbT is released to stimulate RsbU%2C a PP2C phosphatase%2C thereby initiating the signaling cascade that ultimately activates sigma-B. The activity of the RsbU phosphatase may be stimulated by a long-lived interaction with RsbT and the serine kinase function of RsbT is not required to directly modify RsbU. Also phosphorylates RsbR thanks to its threonine kinase activity%2C preventing it to phosphorylate RsbT%3B KEGG: bsu:BSU04690 serine/threonine-protein kinase RsbT gene gene560 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00561 S100027_00562 S100027_00562 S100027_00562 561472 562479 + Phosphoserine phosphatase RsbU Hydrolase%3B Protein phosphatase%3B Positive regulator of sigma-B activity. Dephosphorylates RsbV in response to environmental stress conveyed from the RsbXST module%3B Contains 1 PPM-type phosphatase domain gene gene561 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00562 S100027_00563 S100027_00563 S100027_00563 562538 562864 + Anti-sigma-B factor antagonist Phosphoprotein%3B Positive regulator of sigma-B activity. Non- phosphorylated RsbV binds to RsbW%2C preventing its association with sigma-B. When phosphorylated%2C releases RsbW%2C which is then free to complex with and inactivate sigma-B (By similarity)%3B Belongs to the anti-sigma-factor antagonist family%3B Contains 1 STAS domain gene gene562 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00563 S100027_00564 S100027_00564 rsbW rsbW 562864 563349 + Non-specific serine/threonine protein kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Serine/threonine-protein kinase%3B Transferase%3B Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein%2C RsbV. Upon phosphorylation of RsbV%2C RsbW is released and binds to sigma-B%2C thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)%3B Belongs to the anti-sigma-factor family%3B KEGG: bli:BL02207 serine/threonine-protein kinase RsbW gene gene563 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00564 S100027_00565 S100027_00565 S100027_00565 563312 564106 + RNA polymerase sigma-B factor DNA-binding%3B Sigma factor%3B Stress response%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma B is not essential for sporulatio%3B rather it is required for maximal expression of ctc and csbA which are transcribed in the early stationary phase under conditions inimical to sporulation. May play a role in the ability of the bacterium to adapt to various stresses but is not essential for its survival under these conditions. Positively regulates expression of its own operon. Belongs to the sigma-70 factor family. SigB subfamily gene gene564 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00565 S100027_00566 S100027_00566 rsbX rsbX 564103 564702 + Phosphoserine phosphatase Hydrolase%3B Protein phosphatase%3B Negative regulator of sigma-B activity. Dephosphorylates RsbS. Plays a role both in maintaining low sigma-B activity during growth and in reestablishing prestress sigma-B activity after induction. Could have a negative feedback role by indirectly communicating sigma-B protein levels%3B Contains 1 PPM-type phosphatase domain%3B KEGG: bli:BL02209 negative regulator of sigma-B (phosphoserine phosphatase) gene gene565 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00566 S100027_00567 S100027_00567 S100027_00567 564780 566942 + uncharacterized protein Coiled coil%3B Contains 1 S1 motif domain gene gene566 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00567 S100027_00568 S100027_00568 S100027_00568 566992 567549 - putative HTH-type transcriptional regulator YxbF DNA-binding%3B Repeat%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 2 HTH tetR-type DNA-binding domains gene gene567 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00568 S100027_00569 S100027_00569 S100027_00569 567906 571025 + Putative membrane protein YdgH Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family. MmpL subfamily gene gene568 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00569 S100027_00570 S100027_00570 S100027_00570 571415 571876 + Protein SprT-like Cytoplasm%3B Metal-binding%3B Zinc%3B Belongs to the SprT family%3B Contains 1 SprT-like domain gene gene569 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00570 S100027_00571 S100027_00571 S100027_00571 571993 572067 + tRNA-Asn tRNA gene570 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00571 S100027_00572 S100027_00572 S100027_00572 572070 572160 + tRNA-Ser tRNA gene571 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00572 S100027_00573 S100027_00573 S100027_00573 572189 572260 + tRNA-Glu tRNA gene572 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00573 S100027_00574 S100027_00574 S100027_00574 572273 572347 + tRNA-Gln tRNA gene573 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00574 S100027_00575 S100027_00575 S100027_00575 572356 572431 + tRNA-Lys tRNA gene574 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00575 S100027_00576 S100027_00576 S100027_00576 572444 572526 + tRNA-Leu tRNA gene575 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00576 S100027_00577 S100027_00577 S100027_00577 572547 572630 + tRNA-Leu tRNA gene576 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00577 S100027_00578 S100027_00578 S100027_00578 573020 573370 - hypothetical protein gene gene577 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00578 S100027_00579 S100027_00579 S100027_00579 573360 573599 - putative HTH-type transcriptional regulator DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene578 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00579 S100027_00580 S100027_00580 fad6 fad6 574237 575265 - Fatty acid desaturase Cell membrane%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsaturated fatty acids%3B Belongs to the fatty acid desaturase family%3B KEGG: bsr:I33_0567 omega-6 fatty acid desaturase (delta-12 desaturase)%3B With oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water gene gene579 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00580 S100027_00581 S100027_00581 S100027_00581 575864 576067 + Cold shock protein Activator%3B Cytoplasm%3B DNA-binding%3B Stress response%3B Transcription%3B Transcription regulation%3B Contains 1 CSD (cold-shock) domain gene gene580 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00581 S100027_00582 S100027_00582 mecR mecR 576323 577309 - Trans-2-enoyl-CoA reductase (NADPH) Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Mitochondrion%3B NADP%3B Oxidoreductase%3B Transit peptide%3B Oxidoreductase with a preference for short and medium chain substrates%2C including trans-2-hexenoyl-CoA (C6)%2C trans-2- decenoyl-CoA (C10)%2C and trans-2-hexadecenoyl-CoA (C16). May play a role in mitochondrial fatty acid synthesis (By similarity)%3B Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily%3B KEGG: tsp:Tsp_07030 mitochondrial trans-2-enoyl-CoA reductase gene gene581 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00582 S100027_00583 S100027_00583 S100027_00583 577369 577680 - hypothetical protein gene gene582 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00583 S100027_00584 S100027_00584 S100027_00584 577677 578282 - uncharacterized protein gene gene583 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00584 S100027_00585 S100027_00585 S100027_00585 578391 578846 + putative HTH-type transcriptional regulator YybA DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH marR-type DNA-binding domain gene gene584 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00585 S100027_00586 S100027_00586 S100027_00586 578871 579389 + Spermidine/spermine N(1)-acetyltransferase Acyltransferase%3B Sporulation%3B Transferase%3B Involved in the protection against polyamine toxicity by regulating their concentration. Also could be involved in the negative control of sporulation as well as production of degradative enzymes such as alpha-amylase%2C levansucrase and alkaline phosphatase. Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to an acceptor substrate and releases both CoA and the acetylated product. It possesses N1- acetyltransferase activity toward polyamine substrates including spermidine%2C spermine%2C aminopropylcadaverine%2C norspermidine%2C homospermidine%2C N(8)-acetylspermidine%2C diaminopropane and agmatine%3B Contains 1 N-acetyltransferase domain%3B KEGG: gfo:GFO_2080 null%3B Transferring groups other than amino-acyl groups gene gene585 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00586 S100027_00587 S100027_00587 S100027_00587 579411 580028 + Protease synthase and sporulation protein PAI Sporulation%3B Involved in the reduction of extracellular and cell- associated protease levels%2C as well as in the reduced levels of alpha-amylase%2C levansucrase%2C alkaline phosphatase and sporulation inhibition%2C when present in high copy number. Belongs to the PaiB family gene gene586 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00587 S100027_00588 S100027_00588 S100027_00588 580423 581337 - Arginase KEGG: xfa:XF1250 arginase gene gene587 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00588 S100027_00589 S100027_00589 S100027_00589 581443 581778 + putative HTH-type transcriptional regulator DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH hxlR-type DNA-binding domain gene gene588 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00589 S100027_00590 S100027_00590 S100027_00590 582117 582989 + UPF0750 membrane protein YdeO Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0750 family gene gene589 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00590 S100027_00591 S100027_00591 S100027_00591 583088 583537 - Cysteine/O-acetylserine efflux protein Amino-acid transport%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Exporter of O-acetylserine (OAS) and cysteine%3B Belongs to the rht family gene gene590 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00591 S100027_00592 S100027_00592 S100027_00592 583799 584680 + HTH-type transcriptional regulator SoxR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcriptional repressor of soxA gene expression. Contains 1 HTH lysR-type DNA-binding domain gene gene591 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00592 S100027_00593 S100027_00593 S100027_00593 584762 584983 + hypothetical protein gene gene592 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00593 S100027_00594 S100027_00594 S100027_00594 585164 586390 + hypothetical protein gene gene593 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00594 S100027_00595 S100027_00595 S100027_00595 586486 587268 - hypothetical protein gene gene594 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00595 S100027_00596 S100027_00596 S100027_00596 587394 588776 - putative transporter YdgF Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probable amino-acid or metabolite transport protein. Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene595 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00596 S100027_00597 S100027_00597 S100027_00597 589178 589813 + hypothetical protein gene gene596 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00597 S100027_00598 S100027_00598 S100027_00598 590006 590641 + hypothetical protein gene gene597 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00598 S100027_00599 S100027_00599 S100027_00599 590983 591480 + RNA polymerase sigma factor SigV Activator%3B DNA-binding%3B Sigma factor%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin%2C paraquat and tellurite%3B Belongs to the sigma-70 factor family. ECF subfamily gene gene598 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00599 S100027_00600 S100027_00600 S100027_00600 591480 592340 + Anti-sigma-V factor RsiV Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Anti-sigma factor for SigV. Negatively regulates SigV activity through direct interaction gene gene599 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00600 S100027_00601 S100027_00601 S100027_00601 592571 594451 + Putative peptidoglycan O-acetyltransferase YrhL Acyltransferase%3B Cell membrane%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Belongs to the acyltransferase 3 family%3B KEGG: mtu:Rv0111 null%3B Transferring groups other than amino-acyl groups gene gene600 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00601 S100027_00602 S100027_00602 S100027_00602 594676 595845 + Bicyclomycin resistance protein Antibiotic resistance%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance. Probable membrane translocase%3B Belongs to the major facilitator superfamily. Bcr/CmlA family gene gene601 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00602 S100027_00603 S100027_00603 phoR phoR 595885 598980 - Histidine kinase Alginate biosynthesis%3B ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Sensory transduction%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Member of the two-component regulatory system AlgB/KinB involved in regulation of alginate biosynthesis genes. KinB functions as a membrane-associated protein kinase that phosphorylates AlgB%2C probably in response to environmental signals. Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B Contains 1 PAC (PAS-associated C-terminal) domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: win:WPG_3498 two-component system%2C OmpR family%2C phosphate regulon sensor histidine kinase PhoR gene gene602 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00603 S100027_00604 S100027_00604 S100027_00604 599155 600231 + Sensory transduction protein LytR Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system LytR/LytS that regulates genes involved in autolysis and cell wall metabolism. Regulates the activity of the cell wall-associated murein hydrolase through regulation of lrgA and lrgB (By similarity)%3B Contains 1 HTH LytTR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene603 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00604 S100027_00605 S100027_00605 S100027_00605 600529 606456 + hypothetical protein gene gene604 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00605 S100027_00606 S100027_00606 srtA srtA 606523 607155 + Sortase A Hydrolase%3B Protease%3B Thiol protease%3B Belongs to the peptidase C60 family%3B KEGG: bli:BL00120 sortase A gene gene605 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00606 S100027_00607 S100027_00607 S100027_00607 607731 609152 + Major myo-inositol transporter IolT Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Major myo-inositol uptake transporter%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene606 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00607 S100027_00608 S100027_00608 S100027_00608 609754 609830 + tRNA-Arg tRNA gene607 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00608 S100027_00609 S100027_00609 S100027_00609 609843 609916 + tRNA-Gly tRNA gene608 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00609 S100027_00610 S100027_00610 S100027_00610 610074 611623 + 16S ribosomal RNA rRNA gene609 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00610 S100027_00611 S100027_00611 S100027_00611 611798 614728 + 23S ribosomal RNA rRNA gene610 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00611 S100027_00612 S100027_00612 S100027_00612 614860 614975 + 5S ribosomal RNA rRNA gene611 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00612 S100027_00613 S100027_00613 S100027_00613 614988 615064 + tRNA-Met tRNA gene612 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00613 S100027_00614 S100027_00614 S100027_00614 615106 615182 + tRNA-Asp tRNA gene613 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00614 S100027_00615 S100027_00615 thiL thiL 615377 616360 + Thiamine-phosphate kinase ATP-binding%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Thiamine biosynthesis%3B Transferase%3B Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP)%2C the active form of vitamin B1%3B Belongs to the thiamine-monophosphate kinase family%3B KEGG: gsb:GSUB_15825 thiamine-monophosphate kinase gene gene614 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00615 S100027_00616 S100027_00616 S100027_00616 616357 616845 + tRNA threonylcarbamoyladenosine biosynthesis protein TsaE ATP-binding%3B Cytoplasm%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B tRNA processing%3B Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37%2C together with TsaD and Tsa%3B this reaction does not require ATP in vitro. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway%2C possibly in regulating the core enzymatic function of TsaD. Displays ATPase activity in vitro%2C which is modulated by the oligomeric status of the protein%3B Belongs to the TsaE family gene gene615 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00616 S100027_00617 S100027_00617 S100027_00617 616826 617515 + tRNA threonylcarbamoyladenosine biosynthesis protein TsaB Cytoplasm%3B tRNA processing%3B Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37%2C together with TsaD and Tsa%3B this reaction does not require ATP in vitro. TsaB seems to play an indirect role in the t(6)A biosynthesis pathway%2C possibly in regulating the core enzymatic function of TsaD%3B Belongs to the KAE1 / TsaD family. TsaB subfamily gene gene616 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00617 S100027_00618 S100027_00618 rimI rimI 617540 617986 + Ribosomal-protein-alanine N-acetyltransferase Acyltransferase%3B Cytoplasm%3B Transferase%3B This enzyme acetylates the N-terminal alanine of ribosomal protein S18%3B Belongs to the acetyltransferase family. RimI subfamily%3B Contains 1 N-acetyltransferase domain%3B KEGG: bli:BL00844 ribosomal-protein-alanine N-acetyltransferase gene gene617 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00618 S100027_00619 S100027_00619 kae1 kae1 617976 619001 + N(6)-L-threonylcarbamoyladenine synthase Acyltransferase%3B Cytoplasm%3B Iron%3B Metal-binding%3B Transferase%3B tRNA processing%3B Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37%2C together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction%3B Belongs to the KAE1 / TsaD family%3B KEGG: bli:BL00845 N6-L-threonylcarbamoyladenine synthase gene gene618 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00619 S100027_00620 S100027_00620 S100027_00620 619241 621166 - Iron-chelate-transporting ATPase ATP-binding%3B Nucleotide-binding%3B Repeat%3B Transport%3B Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily%3B Contains 2 ABC transporter domains%3B KEGG: yee:YE5303_30631 iron complex transport system ATP-binding protein gene gene619 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00620 S100027_00621 S100027_00621 moaC moaC 621313 621819 + Cyclic pyranopterin phosphate synthase Molybdenum cofactor biosynthesis%3B Together with MoaA%2C is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z)%3B Belongs to the MoaC family%3B KEGG: spoi:IMCC21906_01961 cyclic pyranopterin phosphate synthase gene gene620 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00621 S100027_00622 S100027_00622 S100027_00622 621823 622470 + Redox-sensing transcriptional repressor Rex Cytoplasm%3B DNA-binding%3B NAD%3B Repressor%3B Transcription%3B Transcription regulation%3B Modulates transcription in response to changes in cellular NADH/NAD(+) redox state%3B Belongs to the transcriptional regulatory Rex family gene gene621 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00622 S100027_00623 S100027_00623 S100027_00623 622513 622692 + Sec-independent protein translocase protein TatA Cell membrane%3B Membrane%3B Protein transport%3B Translocation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system%3B Belongs to the TatA/E family gene gene622 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00623 S100027_00624 S100027_00624 S100027_00624 622699 623475 + Sec-independent protein translocase protein TatC Cell membrane%3B Membrane%3B Protein transport%3B Translocation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes%3B Belongs to the TatC family gene gene623 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00624 S100027_00625 S100027_00625 S100027_00625 623521 623715 - putative lipoprotein YdiK Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transmembrane%3B Transmembrane helix. gene gene624 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00625 S100027_00626 S100027_00626 S100027_00626 623712 624446 - Putative membrane peptidase YdiL Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Transmembrane%3B Transmembrane helix%3B May function as endopeptidase which proteolytically removes the C-terminal three residues of farnesylated peptides containing the CAAX motif where C is cysteine%2C A is an aliphatic amino acid and X is any amino acid%3B Belongs to the peptidase U48 family gene gene625 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00626 S100027_00627 S100027_00627 S100027_00627 624672 624956 + 10 kDa chaperonin Chaperone%3B Cytoplasm%3B Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter%3B Belongs to the GroES chaperonin family gene gene626 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00627 S100027_00628 S100027_00628 S100027_00628 625001 626635 + 60 kDa chaperonin ATP-binding%3B Chaperone%3B Cytoplasm%3B Nucleotide-binding%3B Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions%3B Belongs to the chaperonin (HSP60) family gene gene627 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00628 S100027_00629 S100027_00629 S100027_00629 626717 627934 - Integrase DNA integration%3B DNA recombination%3B Hydrolase%3B Transferase%3B Viral genome integration%3B Virus entry into host cell%3B Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase%2C integrase is also necessary for excision of the prophage from the host genome. It may bind the DNA. Belongs to the 'phage' integrase family gene gene628 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00629 S100027_00630 S100027_00630 lexA lexA 627948 628580 - Repressor LexA Autocatalytic cleavage%3B DNA damage%3B DNA repair%3B DNA replication%3B DNA-binding%3B Hydrolase%3B Repressor%3B SOS response%3B Transcription%3B Transcription regulation%3B Represses a number of genes involved in the response to DNA damage (SOS response)%2C including recA and lexA. In the presence of single-stranded DNA%2C RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA%2C leading to derepression of the SOS regulon and eventually DNA repair%3B Belongs to the peptidase S24 family%3B KEGG: blh:BaLi_c06700 repressor LexA gene gene629 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00630 S100027_00631 S100027_00631 S100027_00631 628745 628993 + hypothetical protein gene gene630 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00631 S100027_00632 S100027_00632 S100027_00632 629227 629928 + hypothetical protein gene gene631 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00632 S100027_00633 S100027_00633 S100027_00633 629941 630339 + hypothetical protein gene gene632 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00633 S100027_00634 S100027_00634 S100027_00634 630336 630425 + hypothetical protein gene gene633 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00634 S100027_00635 S100027_00635 S100027_00635 630438 630782 + hypothetical protein gene gene634 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00635 S100027_00636 S100027_00636 S100027_00636 630787 630996 + hypothetical protein gene gene635 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00636 S100027_00637 S100027_00637 S100027_00637 630986 631198 - hypothetical protein gene gene636 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00637 S100027_00638 S100027_00638 S100027_00638 631253 631471 + hypothetical protein gene gene637 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00638 S100027_00639 S100027_00639 S100027_00639 631573 631791 + hypothetical protein gene gene638 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00639 S100027_00640 S100027_00640 S100027_00640 631784 632662 + hypothetical protein gene gene639 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00640 S100027_00641 S100027_00641 S100027_00641 632646 633479 + hypothetical protein gene gene640 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00641 S100027_00642 S100027_00642 S100027_00642 633493 633651 + hypothetical protein gene gene641 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00642 S100027_00643 S100027_00643 S100027_00643 633648 633806 + hypothetical protein gene gene642 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00643 S100027_00644 S100027_00644 S100027_00644 633803 634351 + hypothetical protein gene gene643 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00644 S100027_00645 S100027_00645 S100027_00645 634456 634605 + hypothetical protein gene gene644 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00645 S100027_00646 S100027_00646 S100027_00646 634676 634876 + Phage-like element PBSX protein XtrA To B. subtilis YqaO gene gene645 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00646 S100027_00647 S100027_00647 S100027_00647 634912 635145 + hypothetical protein gene gene646 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00647 S100027_00648 S100027_00648 S100027_00648 635142 635483 + hypothetical protein gene gene647 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00648 S100027_00649 S100027_00649 S100027_00649 635483 635659 + hypothetical protein gene gene648 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00649 S100027_00650 S100027_00650 S100027_00650 635659 635907 + hypothetical protein gene gene649 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00650 S100027_00651 S100027_00651 S100027_00651 636205 636645 + putative phage-related protein gene gene650 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00651 S100027_00652 S100027_00652 S100027_00652 636645 637187 + putative integrase/recombinase YoeC DNA integration%3B DNA recombination%3B DNA-binding%3B Viral genome integration%3B Virus entry into host cell%3B Belongs to the 'phage' integrase family gene gene651 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00652 S100027_00653 S100027_00653 S100027_00653 637417 638220 + hypothetical protein gene gene652 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00653 S100027_00654 S100027_00654 S100027_00654 638561 638782 + hypothetical protein gene gene653 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00654 S100027_00655 S100027_00655 S100027_00655 638785 639030 + hypothetical protein gene gene654 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00655 S100027_00656 S100027_00656 S100027_00656 639018 639659 + hypothetical protein gene gene655 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00656 S100027_00657 S100027_00657 S100027_00657 640162 640488 + hypothetical protein gene gene656 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00657 S100027_00658 S100027_00658 S100027_00658 640575 641108 + hypothetical protein gene gene657 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00658 S100027_00659 S100027_00659 S100027_00659 641108 642775 + uncharacterized protein Belongs to the phage terminase family gene gene658 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00659 S100027_00660 S100027_00660 S100027_00660 642827 642997 + hypothetical protein gene gene659 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00660 S100027_00661 S100027_00661 S100027_00661 643003 643212 + hypothetical protein gene gene660 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00661 S100027_00662 S100027_00662 S100027_00662 643826 644239 + hypothetical protein gene gene661 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00662 S100027_00663 S100027_00663 S100027_00663 644229 644858 + hypothetical protein gene gene662 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00663 S100027_00664 S100027_00664 S100027_00664 644899 645240 + hypothetical protein gene gene663 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00664 S100027_00665 S100027_00665 S100027_00665 645204 646214 + hypothetical protein gene gene664 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00665 S100027_00666 S100027_00666 S100027_00666 646240 646689 + Collagen alpha-1(V) chain Collagen%3B Extracellular matrix%3B Heparin-binding%3B Hydroxylation%3B Repeat%3B Secreted%3B Signal%3B Sulfation%3B Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA%2C heparan sulfate%2C thrombospondin%2C heparin%2C and insulin (By similarity)%3B Belongs to the fibrillar collagen family%3B Contains 1 fibrillar collagen NC1 domain%3B Contains 1 laminin G-like domain gene gene665 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00666 S100027_00667 S100027_00667 S100027_00667 646705 647055 + hypothetical protein gene gene666 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00667 S100027_00668 S100027_00668 S100027_00668 647351 647734 + hypothetical protein gene gene667 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00668 S100027_00669 S100027_00669 S100027_00669 647731 648111 + hypothetical protein gene gene668 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00669 S100027_00670 S100027_00670 S100027_00670 648111 648719 + hypothetical protein gene gene669 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00670 S100027_00671 S100027_00671 S100027_00671 648779 649114 + hypothetical protein gene gene670 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00671 S100027_00672 S100027_00672 S100027_00672 649312 653202 + Tape measure protein Host membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Viral tail assembly%3B Virus exit from host cell%3B Plays a role in virion tail formation. The length of the tape measure protein is proportional to the length of the phage's tail gene gene671 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00672 S100027_00673 S100027_00673 S100027_00673 653202 654038 + hypothetical protein gene gene672 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00673 S100027_00674 S100027_00674 S100027_00674 654051 655760 + N-acetylmuramoyl-L-alanine amidase Cell wall%3B Cell wall biogenesis/degradation%3B Glycosidase%3B Hydrolase%3B Magnesium%3B Secreted%3B Signal%3B Is the major glucosaminidase responsible for peptidoglycan structural determination during vegetative growth. Acts processively from the ends of the glycan strands. Also plays a role in motility%2C chemotaxis and cell division%3B Belongs to the glycosyl hydrolase 73 family%3B KEGG: smu:SMU_76 N-acetylmuramoyl-L-alanine amidase gene gene673 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00674 S100027_00675 S100027_00675 S100027_00675 655797 657371 + hypothetical protein gene gene674 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00675 S100027_00676 S100027_00676 S100027_00676 657408 658754 + Phage-like element PBSX protein XkdV To B. subtilis YqcC gene gene675 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00676 S100027_00677 S100027_00677 S100027_00677 658767 659090 + SPBc2 prophage-derived uncharacterized protein YomQ gene gene676 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00677 S100027_00678 S100027_00678 S100027_00678 659087 659272 + hypothetical protein gene gene677 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00678 S100027_00679 S100027_00679 S100027_00679 659335 659604 + putative 11.0 kDa protein in cwlL 5'region To B. licheniformis xpaL1 and to B. subtilis XhlA gene gene678 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00679 S100027_00680 S100027_00680 S100027_00680 659620 659883 + SPBc2 prophage-derived protein BhlB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B May be involved in the secretion of the autolysin BlyA. Belongs to the SPP1 holin family gene gene679 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00680 S100027_00681 S100027_00681 S100027_00681 659935 660777 + N-acetylmuramoyl-L-alanine amidase Cell wall biogenesis/degradation%3B Hydrolase%3B Repeat%3B Secreted%3B Signal%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B KEGG: bli:BL01582 N-acetylmuramoyl-L-alanine amidase gene gene680 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00681 S100027_00682 S100027_00682 S100027_00682 660848 661192 - hypothetical protein gene gene681 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00682 S100027_00683 S100027_00683 S100027_00683 661211 662932 - Ribonuclease YxiD Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene682 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00683 S100027_00684 S100027_00684 S100027_00684 663125 663439 - hypothetical protein gene gene683 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00684 S100027_00685 S100027_00685 S100027_00685 663519 663671 - hypothetical protein gene gene684 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00685 S100027_00686 S100027_00686 S100027_00686 663978 664118 - hypothetical protein gene gene685 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00686 S100027_00687 S100027_00687 S100027_00687 664531 664767 - hypothetical protein gene gene686 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00687 S100027_00688 S100027_00688 S100027_00688 665000 665341 - hypothetical protein gene gene687 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00688 S100027_00689 S100027_00689 S100027_00689 665776 666012 - hypothetical protein gene gene688 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00689 S100027_00690 S100027_00690 S100027_00690 666797 667006 + hypothetical protein gene gene689 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00690 S100027_00691 S100027_00691 S100027_00691 667149 668066 + uncharacterized protein gene gene690 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00691 S100027_00692 S100027_00692 S100027_00692 668184 668633 + uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix. gene gene691 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00692 S100027_00693 S100027_00693 S100027_00693 668857 669318 + hypothetical protein gene gene692 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00693 S100027_00694 S100027_00694 S100027_00694 669383 670057 - Putative SOS response-associated peptidase YoaM Hydrolase%3B Protease%3B Belongs to the SOS response-associated peptidase family gene gene693 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00694 S100027_00695 S100027_00695 S100027_00695 670489 670971 + putative HTH-type transcriptional regulator YerO DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH tetR-type DNA-binding domain gene gene694 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00695 S100027_00696 S100027_00696 ppsA ppsA 671094 673715 + Pyruvate%2C water dikinase Transferase%3B Might catalyze the phosphorylation of pyruvate to phosphoenolpyruvate%3B Belongs to the PEP-utilizing enzyme family%3B KEGG: bli:BL01065 pyruvate%2C water dikinase gene gene695 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00696 S100027_00697 S100027_00697 S100027_00697 673743 674027 - uncharacterized protein gene gene696 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00697 S100027_00698 S100027_00698 S100027_00698 674093 674455 - DNA-3-methyladenine glycosylase II To M. tuberculosis Rv3073c%3B KEGG: btp:D805_0940 DNA-3-methyladenine glycosylase gene gene697 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00698 S100027_00699 S100027_00699 dltE dltE 674539 675303 - putative oxidoreductase DltE Cytoplasm%3B NAD%3B Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: enr:H650_10080 uncharacterized oxidoreductase%3B Oxidoreductases gene gene698 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00699 S100027_00700 S100027_00700 pnbA pnbA 675455 676927 + Para-nitrobenzyl esterase Hydrolase%3B Phosphoprotein%3B Serine esterase%3B Catalyzes hydrolysis of several beta-lactam antibiotic PNB esters to the corresponding free acid and PNB alcohol. Belongs to the type-B carboxylesterase/lipase family%3B KEGG: bli:BL01300 para-nitrobenzyl esterase%3B Carboxylic ester hydrolases gene gene699 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00700 S100027_00701 S100027_00701 S100027_00701 676952 678229 - Minor myo-inositol transporter IolF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Minor myo-inositol uptake transporter%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene700 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00701 S100027_00702 S100027_00702 S100027_00702 678599 679279 + Phage shock protein Cell inner membrane%3B Cell membrane%3B Coiled coil%3B Cytoplasm%3B Membrane%3B The phage shock protein (psp) operon (pspABCDE) may play a significant role in the competition for survival under nutrient- or energy-limited conditions. PspA negatively regulates expression of the pspABCDE promoter and of pspG through negative regulation of the psp-specific transcriptional activator PspF. Is also required for membrane integrity%2C efficient translocation and maintenance of the proton motive force (By similarity)%3B Belongs to the PspA/IM30 family gene gene701 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00702 S100027_00703 S100027_00703 S100027_00703 679314 680339 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene702 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00703 S100027_00704 S100027_00704 S100027_00704 680339 681106 + UPF0603 protein YdjH Cell membrane%3B Membrane%3B Signal%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0603 family gene gene703 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00704 S100027_00705 S100027_00705 S100027_00705 681128 682102 + uncharacterized protein gene gene704 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00705 S100027_00706 S100027_00706 S100027_00706 682362 683417 + uncharacterized protein Monooxygenase%3B Oxidoreductase%3B Plasmid%3B Belongs to the bacterial luciferase oxidoreductase family%3B KEGG: ret:RHE_CH03117 null%3B Oxidoreductases gene gene705 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00706 S100027_00707 S100027_00707 zntA zntA 683450 684277 - Cadmium-exporting ATPase Coiled coil%3B KEGG: cau:Caur_3747 Cd2+/Zn2+-exporting ATPase gene gene706 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00707 S100027_00708 S100027_00708 S100027_00708 684424 685056 + putative membrane protein YrhP Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the rht family gene gene707 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00708 S100027_00709 S100027_00709 S100027_00709 685251 685895 + hypothetical protein gene gene708 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00709 S100027_00710 S100027_00710 S100027_00710 685911 687068 + Putative lipid II flippase Cell cycle%3B Cell division%3B Cell inner membrane%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Peptidoglycan synthesis%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Essential cell division protein. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane%3B Belongs to the SEDS family. FtsW subfamily gene gene709 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00710 S100027_00711 S100027_00711 S100027_00711 687065 688213 + Putative lipid II flippase FtsW Cell cycle%3B Cell division%3B Cell inner membrane%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Peptidoglycan synthesis%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Essential cell division protein. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane%3B Belongs to the SEDS family. FtsW subfamily gene gene710 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00711 S100027_00712 S100027_00712 S100027_00712 688902 689327 - hypothetical protein gene gene711 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00712 S100027_00713 S100027_00713 S100027_00713 689422 690369 + putative HTH-type transcriptional regulator YobV Cytoplasm%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH deoR-type DNA-binding domain gene gene712 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00713 S100027_00714 S100027_00714 S100027_00714 690647 691324 + hypothetical protein gene gene713 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00714 S100027_00715 S100027_00715 S100027_00715 691396 692775 + Peptidoglycan-N-acetylmuramic acid deacetylase PdaC Cell membrane%3B Hydrolase%3B Membrane%3B Metal-binding%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the deacetylation of N-acetylmuramic acid (MurNAc) residues in peptidoglycan%2C a modification that confers resistance to lysosyme. Is not able to deacetylate N- acetylglucosamine (GlcNAc) residues in peptidoglycan%2C but can deacylate chitin oligomers such as GlcNAc4 and GlcNAc5. Is essentially not active toward chitosan (partially deacetylated GlcNAc polymer) and has very low activity toward chitin (GlcNAc polymer). Does not deacetylate GlcNAc%3B Belongs to the polysaccharide deacetylase family%3B KEGG: baci:B1NLA3E_02370 peptidoglycan-N-acetylmuramic acid deacetylase%3B In linear amides gene gene714 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00715 S100027_00716 S100027_00716 amyA amyA 692904 694442 + Alpha-amylase Calcium%3B Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Metal-binding%3B Signal%3B Belongs to the glycosyl hydrolase 13 family%3B KEGG: bli:BL00499 alpha-amylase gene gene715 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00716 S100027_00717 S100027_00717 S100027_00717 694605 695555 + putative HTH-type transcriptional regulator YvdE DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH lacI-type DNA-binding domain gene gene716 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00717 S100027_00718 S100027_00718 S100027_00718 695675 697435 + Glucan 1%2C4-alpha-maltohydrolase Carbohydrate metabolism%3B Cytoplasm%3B Glycosidase%3B Hydrolase%3B Hydrolyzes beta-cyclodextrin to maltose and glucose%2C soluble starch to maltose and glucose%2C and pullulan to panose with trace amounts of maltose and glucose. It is also able to hydrolyze acarbose. Can also exhibit a transglycosylation activity transferring glucose or maltose to another moiety of sugars by forming alpha-(1%2C6)- and alpha-(1%2C3)-glycosidic linkages upon the hydrolysis of substrate at concentrations of 5%25 or higher%3B Belongs to the glycosyl hydrolase 13 family. BbmA subfamily%3B KEGG: bld:BLi00658 null gene gene717 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00718 S100027_00719 S100027_00719 S100027_00719 697530 698783 + Maltodextrin-binding protein MdxE Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Polysaccharide transport%3B Signal%3B Sugar transport%3B Transport%3B Part of the ABC transporter complex involved in maltodextrin import. Binds maltodextrin. Can also bind maltose with low affinity%2C but is not involved in its uptake%3B Belongs to the bacterial solute-binding protein 1 family gene gene718 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00719 S100027_00720 S100027_00720 S100027_00720 698825 700132 + Maltodextrin transport system permease protein MalC Cell membrane%3B Membrane%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system for maltodextri%3B probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene719 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00720 S100027_00721 S100027_00721 S100027_00721 700133 700984 + Maltodextrin transport system permease protein MdxG Cell membrane%3B Membrane%3B Polysaccharide transport%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex involved in maltodextrin import. Probably responsible for the translocation of the substrate across the membrane (Probable)%3B Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene720 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00721 S100027_00722 S100027_00722 S100027_00722 700989 701870 + Putative maltodextrin utilization protein YvdJ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene721 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00722 S100027_00723 S100027_00723 mapA mapA 701848 704130 + Maltose phosphorylase Carbohydrate metabolism%3B Glycosyltransferase%3B Transferase%3B Catalyzes the phosphorolysis of maltose%2C leading to the formation of glucose and glucose 1-P%3B Belongs to the glycosyl hydrolase 65 family%3B KEGG: bsu:BSU34570 maltose phosphorylase gene gene722 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00723 S100027_00724 S100027_00724 malZ malZ 704127 705833 + Alpha-glucosidase Cytoplasm%3B Glycosidase%3B Hydrolase%3B Hydrolyzes various disaccharides such as sucrose%2C maltose%2C and isomaltose with different efficiencies. Also hydrolyzes longer maltodextrins from maltotriose up to maltohexaose%2C but not maltoheptaose%2C palatinose%2C isomaltotriose%2C or isomaltotetraose. Belongs to the glycosyl hydrolase 13 family%3B KEGG: rah:Rahaq_2679 alpha-glucosidase gene gene723 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00724 S100027_00725 S100027_00725 S100027_00725 705830 706510 + Beta-phosphoglucomutase Carbohydrate metabolism%3B Cytoplasm%3B Isomerase%3B Magnesium%3B Metal-binding%3B Phosphoprotein%3B Catalyzes the interconversion of D-glucose 1-phosphate (G1P) and D-glucose 6-phosphate (G6P)%2C and forming beta-D-glucose 1%2C6-(bis)phosphate (beta-G16P) as an intermediate. The beta- phosphoglucomutase (Beta-PGM) acts on the beta-C(1) anomer of G1P. It plays a key role in the regulation of the flow of carbohydrate intermediates in glycolysis and the formation of the sugar nucleotide UDP-glucose (By similarity)%3B Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family gene gene724 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00725 S100027_00726 S100027_00726 yarS yarS 706793 708046 - Tyrosine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B RNA-binding%3B Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)%3B Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily%3B Contains 1 S4 RNA-binding domain%3B KEGG: bli:BL00484 tyrosyl-tRNA synthetase gene gene725 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00726 S100027_00727 S100027_00727 S100027_00727 708302 708808 - putative HTH-type transcriptional regulator YwaE DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH marR-type DNA-binding domain gene gene726 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00727 S100027_00728 S100027_00728 S100027_00728 708945 709511 - hypothetical protein gene gene727 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00728 S100027_00729 S100027_00729 S100027_00729 709508 709900 - hypothetical protein gene gene728 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00729 S100027_00730 S100027_00730 S100027_00730 710102 710482 + uncharacterized protein gene gene729 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00730 S100027_00731 S100027_00731 S100027_00731 710539 711558 + uncharacterized protein Signal. gene gene730 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00731 S100027_00732 S100027_00732 S100027_00732 711601 712593 - uncharacterized protein gene gene731 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00732 S100027_00733 S100027_00733 S100027_00733 712686 712988 - hypothetical protein gene gene732 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00733 S100027_00734 S100027_00734 S100027_00734 713120 713377 - hypothetical protein gene gene733 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00734 S100027_00735 S100027_00735 lepB lepB 713665 714213 + Signal peptidase I Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Essential for cell viability%3B Belongs to the peptidase S26 family%3B KEGG: bli:BL00487 signal peptidase I gene gene734 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00735 S100027_00736 S100027_00736 S100027_00736 714665 714949 + hypothetical protein gene gene735 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00736 S100027_00737 S100027_00737 codA codA 715268 715912 + Cytosine deaminase Lyase%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: sfa:Sfla_2548 cytosine deaminase gene gene736 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00737 S100027_00738 S100027_00738 S100027_00738 715955 716827 - Lactose operon transcription activator Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Transcriptional regulator of the lacPH genes for lactose utilization. Contains 1 HTH araC/xylS-type DNA-binding domain gene gene737 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00738 S100027_00739 S100027_00739 S100027_00739 716936 718477 - Spore coat protein Sporulation%3B Involved in brown pigmentation during sporogenesis. To S. antibioticus phenoxazinone synthase (PhsA) gene gene738 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00739 S100027_00740 S100027_00740 S100027_00740 718749 719759 + hypothetical protein gene gene739 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00740 S100027_00741 S100027_00741 S100027_00741 719797 720294 - hypothetical protein gene gene740 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00741 S100027_00742 S100027_00742 S100027_00742 720941 721813 + putative transporter YeaB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the cation diffusion facilitator (CDF) transporter (TC 2. A. 4) family gene gene741 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00742 S100027_00743 S100027_00743 S100027_00743 721973 722935 + uncharacterized protein ATP-binding%3B Nucleotide-binding%3B Belongs to the MoxR family%3B KEGG: bsu:BSU06330 MoxR-like ATPase%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances%3B overlaps another CDS with the same product name gene gene742 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00743 S100027_00744 S100027_00744 S100027_00744 722935 724146 + uncharacterized protein overlaps another CDS with the same product name gene gene743 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00744 S100027_00745 S100027_00745 S100027_00745 724151 726376 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene744 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00745 S100027_00746 S100027_00746 guaA guaA 726565 728106 + GMP synthase (glutamine-hydrolyzing) ATP-binding%3B Glutamine amidotransferase%3B GMP biosynthesis%3B Ligase%3B Nucleotide-binding%3B Purine biosynthesis%3B Catalyzes the synthesis of GMP from XMP%3B Contains 1 glutamine amidotransferase type-1 domain%3B Contains 1 GMPS ATP-PPase (ATP pyrophosphatase) domain%3B KEGG: bsu:BSU06360 GMP synthase (glutamine-hydrolysing) gene gene745 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00746 S100027_00747 S100027_00747 S100027_00747 728730 730052 + Putative permease Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2. A. 1. 40) subfamily gene gene746 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00747 S100027_00748 S100027_00748 S100027_00748 730269 731027 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene747 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00748 S100027_00749 S100027_00749 S100027_00749 731149 731337 + hypothetical protein gene gene748 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00749 S100027_00750 S100027_00750 S100027_00750 731523 732077 + UPF0316 protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0316 family gene gene749 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00750 S100027_00751 S100027_00751 S100027_00751 732077 732274 + uncharacterized protein gene gene750 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00751 S100027_00752 S100027_00752 purE purE 732592 733080 + 5-(carboxyamino)imidazole ribonucleotide mutase ATP-binding%3B Decarboxylase%3B Lyase%3B Nucleotide-binding%3B Phosphoprotein%3B Purine biosynthesis%3B In the C-terminal sectio%3B belongs to the AIR carboxylase family. Class I subfamily%3B Contains 1 ATP-grasp domain%3B KEGG: sml:Smlt1613 5-(carboxyamino)imidazole ribonucleotide mutase gene gene751 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00752 S100027_00753 S100027_00753 purK purK 733064 734215 + 5-(carboxyamino)imidazole ribonucleotide synthase ATP-binding%3B Ligase%3B Nucleotide-binding%3B Purine biosynthesis%3B Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)%3B Belongs to the PurK/PurT family%3B Contains 1 ATP-grasp domain%3B KEGG: bld:BLi00694 5-(carboxyamino)imidazole ribonucleotide synthase gene gene752 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00753 S100027_00754 S100027_00754 purB purB 734212 735507 + Adenylosuccinate lyase Lyase%3B Purine biosynthesis%3B Influences the affinity of glutamyl--tRNA ligase for its substrates and increases its thermostability. Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily%3B KEGG: afe:Lferr_1990 adenylosuccinate lyase gene gene753 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00754 S100027_00755 S100027_00755 purC purC 735582 736298 + Phosphoribosylaminoimidazolesuccinocarboxamide synthase ATP-binding%3B Ligase%3B Nucleotide-binding%3B Purine biosynthesis%3B Belongs to the SAICAR synthetase family%3B KEGG: bsu:BSU06450 phosphoribosylaminoimidazole-succinocarboxamide synthase gene gene754 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00755 S100027_00756 S100027_00756 purL purL 736300 736554 + Phosphoribosylformylglycinamidine synthase ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Purine biosynthesis%3B Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL%3B Belongs to the PurS family%3B KEGG: bsu:BSU06460 phosphoribosylformylglycinamidine synthase%3B overlaps another CDS with the same product name gene gene755 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00756 S100027_00757 S100027_00757 S100027_00757 736551 737234 + Phosphoribosylformylglycinamidine synthase ATP-binding%3B Cytoplasm%3B Glutamine amidotransferase%3B Hydrolase%3B Ligase%3B Nucleotide-binding%3B Purine biosynthesis%3B Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: bsu:BSU06470 phosphoribosylformylglycinamidine synthase%3B overlaps another CDS with the same product name gene gene756 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00757 S100027_00758 S100027_00758 S100027_00758 737218 739446 + Phosphoribosylformylglycinamidine synthase ATP-binding%3B Cytoplasm%3B Ligase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Purine biosynthesis%3B Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL%3B Belongs to the FGAMS family%3B KEGG: bsu:BSU06480 phosphoribosylformylglycinamidine synthase%3B overlaps another CDS with the same product name gene gene757 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00758 S100027_00759 S100027_00759 purF purF 739422 740852 + Amidophosphoribosyltransferase 4Fe-4S%3B Allosteric enzyme%3B Glutamine amidotransferase%3B Glycosyltransferase%3B Iron%3B Iron-sulfur%3B Magnesium%3B Metal-binding%3B Purine biosynthesis%3B Transferase%3B Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine%3B In the C-terminal sectio%3B belongs to the purine/pyrimidine phosphoribosyltransferase family%3B Contains 1 glutamine amidotransferase type-2 domain%3B KEGG: bsu:BSU06490 amidophosphoribosyltransferase gene gene758 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00759 S100027_00760 S100027_00760 purM purM 740973 742016 + Phosphoribosylformylglycinamidine cyclo-ligase ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Purine biosynthesis%3B Belongs to the AIR synthase family%3B KEGG: bld:BLi00701 phosphoribosylformylglycinamidine cyclo-ligase gene gene759 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00760 S100027_00761 S100027_00761 purN purN 742013 742600 + Phosphoribosylglycinamide formyltransferase Purine biosynthesis%3B Transferase%3B Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR)%2C producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate%3B Belongs to the GART family%3B KEGG: bsu:BSU06510 phosphoribosylglycinamide formyltransferase 1 gene gene760 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00761 S100027_00762 S100027_00762 purH purH 742597 744135 + Phosphoribosylaminoimidazolecarboxamide formyltransferase Hydrolase%3B Multifunctional enzyme%3B Purine biosynthesis%3B Transferase%3B Belongs to the PurH family%3B KEGG: bpn:BPEN_575 phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase gene gene761 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00762 S100027_00763 S100027_00763 purD purD 744149 745417 + Phosphoribosylamine--glycine ligase ATP-binding%3B Ligase%3B Magnesium%3B Manganese%3B Metal-binding%3B Nucleotide-binding%3B Purine biosynthesis%3B Belongs to the GARS family%3B Contains 1 ATP-grasp domain%3B KEGG: pbr:PB2503_12869 phosphoribosylamine--glycine ligase gene gene762 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00763 S100027_00764 S100027_00764 S100027_00764 745737 746045 - hypothetical protein gene gene763 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00764 S100027_00765 S100027_00765 S100027_00765 746184 747407 + Putative cytochrome P450 YjiB Heme%3B Iron%3B Metal-binding%3B Monooxygenase%3B Oxidoreductase%3B Belongs to the cytochrome P450 family%3B KEGG: bay:RBAM_012290 null%3B Acting on paired donors%2C with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O(2) gene gene764 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00765 S100027_00766 S100027_00766 S100027_00766 747981 748091 + hypothetical protein gene gene765 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00766 S100027_00767 S100027_00767 S100027_00767 748103 748549 + putative lipoprotein YybP Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal. gene gene766 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00767 S100027_00768 S100027_00768 S100027_00768 748652 749068 + hypothetical protein gene gene767 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00768 S100027_00769 S100027_00769 S100027_00769 749147 749377 - putative membrane protein YezF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene768 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00769 S100027_00770 S100027_00770 S100027_00770 749503 751242 + Adenine deaminase Hydrolase%3B Phosphoprotein%3B Belongs to the adenine deaminase family%3B KEGG: bli:BL01492 adenine deaminase gene gene769 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00770 S100027_00771 S100027_00771 S100027_00771 751268 752257 + Putative lipoprotein YerB Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Phosphoprotein%3B Signal. gene gene770 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00771 S100027_00772 S100027_00772 S100027_00772 752260 752571 + uncharacterized protein gene gene771 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00772 S100027_00773 S100027_00773 pcrB pcrB 752722 753408 + Heptaprenylglyceryl phosphate synthase Lipid biosynthesis%3B Lipid metabolism%3B Magnesium%3B Metal-binding%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepP%3B 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P)%2C producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales%3B Belongs to the GGGP/HepGP synthase family%3B KEGG: bsu:BSU06600 putative glycerol-1-phosphate prenyltransferase%3B Transferring alkyl or aryl groups%2C other than methyl groups gene gene772 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00773 S100027_00774 S100027_00774 uvrD uvrD 753468 755687 + DNA helicase ATP-binding%3B DNA damage%3B DNA repair%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B DNA helicase used for plasmid rolling-circle replication and also involved in UV repair. Belongs to the helicase family. UvrD subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: bsu:BSU06610 DNA helicase II / ATP-dependent DNA helicase PcrA gene gene773 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00774 S100027_00775 S100027_00775 ligA ligA 755721 757724 + DNA ligase (NAD(+)) DNA damage%3B DNA repair%3B DNA replication%3B Ligase%3B Magnesium%3B Manganese%3B Metal-binding%3B NAD%3B Zinc%3B DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA%3B Belongs to the NAD-dependent DNA ligase family. LigA subfamily%3B Contains 1 BRCT domain%3B KEGG: bli:BL00589 DNA ligase (NAD+) gene gene774 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00775 S100027_00776 S100027_00776 S100027_00776 757740 758930 + putative lipoprotein YerH Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal. gene gene775 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00776 S100027_00777 S100027_00777 S100027_00777 759119 760045 + uncharacterized protein gene gene776 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00777 S100027_00778 S100027_00778 S100027_00778 760146 760511 + hypothetical protein gene gene777 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00778 S100027_00779 S100027_00779 S100027_00779 760524 760883 + uncharacterized protein gene gene778 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00779 S100027_00780 S100027_00780 S100027_00780 761028 762329 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene779 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00780 S100027_00781 S100027_00781 S100027_00781 762356 763240 + Aryldialkylphosphatase Cobalt%3B Hydrolase%3B Iron%3B Metal-binding%3B Has a low paraoxonase activity. Also active%2C but with a lower activity%2C against other organo-phosphorus insecticides such as Dursban%2C Coumaphos%2C pNP-butanoate or parathion%3B Belongs to the phosphotriesterase family gene gene780 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00781 S100027_00782 S100027_00782 sufS sufS 763237 764385 + Cysteine desulfurase KEGG: frf:LO80_09340 cysteine desulfurase / selenocysteine lyase gene gene781 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00782 S100027_00783 S100027_00783 deoB deoB 764378 765604 + Phosphopentomutase Manganese%3B Metal-binding%3B Belongs to the phosphopentomutase family%3B KEGG: aac:Aaci_1749 phosphopentomutase gene gene782 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00783 S100027_00784 S100027_00784 S100027_00784 765604 766755 + uncharacterized protein gene gene783 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00784 S100027_00785 S100027_00785 nagB nagB 766895 767623 + Glucosamine-6-phosphate deaminase Carbohydrate metabolism%3B Hydrolase%3B Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion%3B Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily%3B KEGG: bli:BL00599 glucosamine-6-phosphate deaminase gene gene784 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00785 S100027_00786 S100027_00786 S100027_00786 767939 768631 - Protein SapB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the MgtC/SapB family gene gene785 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00786 S100027_00787 S100027_00787 S100027_00787 768855 770336 - Osmoregulated proline transporter OpuE Amino-acid transport%3B Cell membrane%3B Membrane%3B Stress response%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Catalyzes the uptake of extracellular proline under high-osmolarity growth conditions. Essential for the use of proline present in the environment as an osmoprotectant%3B Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene786 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00787 S100027_00788 S100027_00788 gatC gatC 770778 771068 + Asparaginyl-tRNA synthase (glutamine-hydrolyzing) ATP-binding%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)%3B Belongs to the GatC family%3B KEGG: mmn:midi_00552 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C gene gene787 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00788 S100027_00789 S100027_00789 gatA gatA 771090 772547 + Asparaginyl-tRNA synthase (glutamine-hydrolyzing) ATP-binding%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)%3B Belongs to the amidase family. GatA subfamily%3B KEGG: bsu:BSU06680 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A gene gene788 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00789 S100027_00790 S100027_00790 gatB gatB 772561 773991 + Asparaginyl-tRNA synthase (glutamine-hydrolyzing) ATP-binding%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)%3B Belongs to the GatB/GatE family. GatB subfamily%3B KEGG: pae:PA4484 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B gene gene789 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00790 S100027_00791 S100027_00791 S100027_00791 774176 774478 + hypothetical protein gene gene790 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00791 S100027_00792 S100027_00792 S100027_00792 774475 774756 + hypothetical protein gene gene791 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00792 S100027_00793 S100027_00793 gmuG gmuG 774831 775913 - Mannan endo-1%2C4-beta-mannosidase Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Polysaccharide degradation%3B Secreted%3B Signal%3B Involved in the degradation of glucomannan. Catalyzes the endo hydrolysis of beta-1%2C4-linked mannan%2C galactomannan and glucomannan%3B Belongs to the glycosyl hydrolase 26 family%3B Contains 1 GH26 (glycosyl hydrolase family 26) domain%3B KEGG: bli:BL05063 mannan endo-1%2C4-beta-mannosidase gene gene792 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00793 S100027_00794 S100027_00794 S100027_00794 776038 776886 - putative HTH-type transcriptional regulator YerO DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH tetR-type DNA-binding domain gene gene793 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00794 S100027_00795 S100027_00795 S100027_00795 777031 780189 + Swarming motility protein SwrC Antibiotic resistance%3B Required for self-resistance to surfactin%2C an antimicrobial lipopeptide surfactant produced by B. subtilis. Also required for swarming motility%3B Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family gene gene794 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00795 S100027_00796 S100027_00796 S100027_00796 780336 780536 + hypothetical protein gene gene795 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00796 S100027_00797 S100027_00797 S100027_00797 780626 781168 - Ribosomal-protein-alanine N-acetyltransferase Acyltransferase%3B Cytoplasm%3B Transferase%3B This enzyme acetylates the N-terminal alanine of ribosomal protein S5%3B Belongs to the acetyltransferase family. RimJ subfamily%3B Contains 1 N-acetyltransferase domain%3B KEGG: bli:BL02628 ribosomal-protein-alanine N-acetyltransferase gene gene796 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00797 S100027_00798 S100027_00798 iunH iunH 781182 782135 - Purine nucleosidase KEGG: bli:BL02627 purine nucleosidase gene gene797 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00798 S100027_00799 S100027_00799 dagK dagK 782335 783249 + Diacylglycerol kinase (ATP) ATP-binding%3B Kinase%3B Lipid biosynthesis%3B Lipid metabolism%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid. Is a key enzyme involved in the production of lipoteichoic acid by reintroducing DAG formed from the breakdown of membrane phospholipids into the phosphatidylglycerol biosynthetic pathway. Is more active toward long-chain DAG compared with short-chain DAG. Is not able to phosphorylate substrates other than DAG%2C such as monoacylglycerol%2C ceramide%2C undecaprenol%2C phosphatidylinositol%2C or sphingosine%3B Belongs to the diacylglycerol/lipid kinase family%3B Contains 1 DAGKc domain%3B KEGG: bsu:BSU06720 diacylglycerol kinase (ATP) gene gene798 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00799 S100027_00800 S100027_00800 rumA rumA 783298 784674 + 23S rRNA (uracil(1939)-C(5))-methyltransferase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family%3B Contains 1 TRAM domain%3B KEGG: bli:BL02629 23S rRNA (uracil1939-C5)-methyltransferase gene gene799 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00800 S100027_00801 S100027_00801 S100027_00801 784502 785134 - uncharacterized protein Coiled coil%3B DNA-binding%3B Contains 1 recombinase DNA-binding domain gene gene800 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00801 S100027_00802 S100027_00802 S100027_00802 785146 786153 - uncharacterized protein Coiled coil%3B DNA-binding%3B Contains 1 recombinase DNA-binding domain gene gene801 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00802 S100027_00803 S100027_00803 S100027_00803 786150 786314 - hypothetical protein gene gene802 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00803 S100027_00804 S100027_00804 S100027_00804 786973 787974 + hypothetical protein gene gene803 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00804 S100027_00805 S100027_00805 S100027_00805 788074 788520 - hypothetical protein gene gene804 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00805 S100027_00806 S100027_00806 S100027_00806 788788 789381 + hypothetical protein gene gene805 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00806 S100027_00807 S100027_00807 hsdM hsdM 789374 790903 + Site-specific DNA-methyltransferase (adenine-specific) Methyltransferase%3B Plasmid%3B Restriction system%3B S-adenosyl-L-methionine%3B Transferase%3B Methylation of specific adenine residue%3B required for both restriction and modification activities (By similarity). The EcoR124/3 I enzyme recognizes 5'-GAAN(7)RTCG-3'%3B Belongs to the N(4)/N(6)-methyltransferase family%3B KEGG: bag:Bcoa_0278 type I restriction enzyme M protein gene gene806 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00807 S100027_00808 S100027_00808 S100027_00808 790928 791776 + DNA-damage-inducible protein gene gene807 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00808 S100027_00809 S100027_00809 hsdS hsdS 791847 792965 + Type I site-specific deoxyribonuclease Coiled coil%3B DNA-binding%3B Repeat%3B Restriction system%3B The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease%2C binding to the same target sequence but cutting the DNA some distance from this site. Whether the DNA is cut or modified depends on the methylation state of the target sequence. When the target site is unmodified%2C the DNA is cut. When the target site is hemimethylated%2C the complex acts as a maintenance MTase modifying the DNA so that both strands become methylated. Subunit S dictates DNA sequences specificity (By similarity)%3B Belongs to the type-I restriction system S methylase family%3B KEGG: fpz:LA55_272 type I restriction enzyme%2C S subunit gene gene808 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00809 S100027_00810 S100027_00810 hsdR hsdR 793009 796116 + Type I site-specific deoxyribonuclease To M. jannaschii MJ1214%3B KEGG: bag:Bcoa_0280 type I restriction enzyme%2C R subunit gene gene809 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00810 S100027_00811 S100027_00811 S100027_00811 796130 796855 + hypothetical protein gene gene810 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00811 S100027_00812 S100027_00812 S100027_00812 797086 797715 + Endoribonuclease EndoA Endonuclease%3B Hydrolase%3B Nuclease%3B RNA-binding%3B Toxin%3B Toxic component of a type II toxin-antitoxin (TA) module. Specific for 5'-UACAU-3' sequences%2C cleaving after the first U (PubMed:21763692). Yields cleavage products with 3' phosphate and 5' hydroxyl groups (PubMed:15882409). Cannot digest substrate with a UUdUACAUAA cleavage site (PubMed:24120662). Overexpression is toxic for cell growth (shown in E. coli)%2C probably by inhibiting protein synthesis through the cleavage of single-stranded RNA. The toxicity is reversed by the antitoxin EndoAI. Toxin activity cannot be inhibited by MazE from E. coli. The EndoA-EndoAI complex does not seem to bind its own promoter (PubMed:24120662)%3B Belongs to the PemK/MazF family%3B KEGG: lcn:C270_06880 mRNA interferase MazF%3B Acting on ester bonds gene gene811 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00812 S100027_00813 S100027_00813 S100027_00813 797974 798177 - hypothetical protein gene gene812 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00813 S100027_00814 S100027_00814 S100027_00814 798252 799367 + hypothetical protein gene gene813 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00814 S100027_00815 S100027_00815 S100027_00815 799478 799810 + hypothetical protein gene gene814 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00815 S100027_00816 S100027_00816 S100027_00816 799780 800640 + putative transposase-like protein DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene815 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00816 S100027_00817 S100027_00817 bglF bglF 801127 802992 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Kinase%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in beta-glucoside transport (By similarity)%3B Contains 1 PTS EIIA type-1 domain%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bpu:BPUM_3644 PTS system%2C beta-glucosides-specific IIA component gene gene816 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00817 S100027_00818 S100027_00818 S100027_00818 802995 804464 + 6-phospho-beta-glucosidase Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P)%2C phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. BglA and BglH are the major proteins contributing to hydrolysis of MUG-P by extracts of late-exponential-phase or stationary-phase B. subtilis cells%3B Belongs to the glycosyl hydrolase 1 family%3B KEGG: bld:BLi00749 6-phospho-beta-glucosidase gene gene817 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00818 S100027_00819 S100027_00819 S100027_00819 804494 805342 + PtsGHI operon antiterminator Activator%3B Phosphoprotein%3B Repeat%3B RNA-binding%3B Transcription%3B Transcription regulation%3B Mediates the positive regulation of the glucose PTS operon (ptsGHI) by functioning as an antiterminator factor of transcription via its interaction with the RNA-antiterminator (RAT) sequence located upstream of the ptsG gene. The RNA-binding domain of GlcT directly binds to the RNA antiterminator (RAT) sequence and prevents transcriptional termination. GlcT binding requires two identical and nearly symmetrical triple base pairings in the RAT sequence%3B Belongs to the transcriptional antiterminator BglG family. GlcT subfamily%3B Contains 2 PRD domains gene gene818 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00819 S100027_00820 S100027_00820 rapK rapK 805590 806702 + Response regulator aspartate phosphatase Hydrolase%3B Protein phosphatase%3B Repeat%3B TPR repeat%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bsu:BSU18910 response regulator aspartate phosphatase K%3B Acting on ester bonds gene gene819 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00820 S100027_00821 S100027_00821 S100027_00821 806699 806821 + hypothetical protein gene gene820 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00821 S100027_00822 S100027_00822 S100027_00822 806987 807745 + hypothetical protein gene gene821 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00822 S100027_00823 S100027_00823 S100027_00823 808157 808876 + putative transcriptional regulatory protein Cytoplasm%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Belongs to the TACO1 family gene gene822 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00823 S100027_00824 S100027_00824 S100027_00824 809033 809242 + putative HTH-type transcriptional regulator DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene823 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00824 S100027_00825 S100027_00825 S100027_00825 809235 809549 + hypothetical protein gene gene824 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00825 S100027_00826 S100027_00826 S100027_00826 809707 811164 + Aldehyde dehydrogenase (NAD(+)) NAD%3B Oxidoreductase%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: bli:BL02341 aldehyde dehydrogenase (NAD+) gene gene825 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00826 S100027_00827 S100027_00827 S100027_00827 811181 812032 + Putative sensory transducer protein YfmS Transducer%3B Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. Attractants increase the level of methylation while repellents decrease the level of methylation (By similarity)%3B Contains 1 methyl-accepting transducer domain gene gene826 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00827 S100027_00828 S100027_00828 S100027_00828 812178 813602 + Sodium-dependent dicarboxylate transporter SdcS Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mediates the transport of the dicarboxylates fumarate%2C malate%2C and succinate across the cytoplasmic membrane via a Na(+)- electrochemical gradient%3B Belongs to the SLC13A/DASS transporter (TC 2. A. 47) family. NADC subfamily gene gene827 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00828 S100027_00829 S100027_00829 S100027_00829 813687 815576 + putative ABC transporter ATP-binding protein YfmR ATP-binding%3B Coiled coil%3B Hydrolase%3B Nucleotide-binding%3B Repeat%3B Transport%3B Belongs to the ABC transporter superfamily%3B Contains 2 ABC transporter domains gene gene828 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00829 S100027_00830 S100027_00830 gch4 gch4 815745 816647 - GTP cyclohydrolase I Hydrolase%3B Converts GTP to 7%2C8-dihydroneopterin triphosphate%3B Belongs to the GTP cyclohydrolase IV family%3B KEGG: bli:BL02349 GTP cyclohydrolase I gene gene829 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00830 S100027_00831 S100027_00831 S100027_00831 816780 817892 + Baeyer-Villiger flavin-containing monooxygenase FAD%3B Flavoprotein%3B Monooxygenase%3B NADP%3B Oxidoreductase%3B Catalyzes a Baeyer-Villiger oxidation reaction%2C i. e. the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl%2C which converts ketones to esters or lactones using NADPH and/or NADH as an electron donor gene gene830 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00831 S100027_00832 S100027_00832 S100027_00832 817916 819559 + Ferrous iron transport protein B like protein ATP-binding%3B Cell inner membrane%3B Cell membrane%3B GTP-binding%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B It seems that the Fe(2+) uptake in C. jejuni cannot be attributed to FeoB%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. FeoB GTPase (TC 9. A. 8) family%3B Contains 1 FeoB-type G (guanine nucleotide-binding) domain gene gene831 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00832 S100027_00833 S100027_00833 S100027_00833 819625 820827 + Putative metal chaperone YciC Chaperone%3B GTP-binding%3B Nucleotide-binding%3B Zinc%3B May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc%3B Belongs to the SIMIBI class G3E GTPase family. CobW subfamily%3B Contains 1 cobW C-terminal domain gene gene832 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00833 S100027_00834 S100027_00834 bioW bioW 820996 821781 + 6-carboxyhexanoate--CoA ligase ATP-binding%3B Biotin biosynthesis%3B Ligase%3B Magnesium%3B Nucleotide-binding%3B Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP%3B Belongs to the BioW family%3B KEGG: bli:BL02411 6-carboxyhexanoate--CoA ligase gene gene833 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00834 S100027_00835 S100027_00835 bioA bioA 821762 823108 + Lysine--8-amino-7-oxononanoate transaminase Aminotransferase%3B Biotin biosynthesis%3B Cytoplasm%3B Pyridoxal phosphate%3B S-adenosyl-L-methionine%3B Transferase%3B Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7%2C8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor%3B Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily%3B KEGG: bli:BL00953 lysine---8-amino-7-oxononanoate aminotransferase gene gene834 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00835 S100027_00836 S100027_00836 bioF bioF 823098 824237 + 8-amino-7-oxononanoate synthase Biotin biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Catalyzes the decarboxylative condensation of pimeloyl- [acyl-carrier protein] and L-alanine to produce 8-amino-7- oxononanoate (AON)%2C [acyl-carrier protein]%2C and carbon dioxide%3B Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily%3B KEGG: bli:BL00954 8-amino-7-oxononanoate synthase gene gene835 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00836 S100027_00837 S100027_00837 bioD bioD 824234 824941 + Dethiobiotin synthase ATP-binding%3B Biotin biosynthesis%3B Cytoplasm%3B Ligase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Catalyzes a mechanistically unusual reaction%2C the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7%2C8-diaminopelargonic acid (DAPA) to form an ureido ring%3B Belongs to the dethiobiotin synthetase family%3B KEGG: acu:Atc_2625 dethiobiotin synthetase gene gene836 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00837 S100027_00838 S100027_00838 bioB bioB 824938 825939 + Biotin synthase 2Fe-2S%3B 4Fe-4S%3B Biotin biosynthesis%3B Iron%3B Iron-sulfur%3B Metal-binding%3B S-adenosyl-L-methionine%3B Transferase%3B Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism%3B Belongs to the radical SAM superfamily. Biotin synthase family%3B KEGG: bsu:BSU30200 biotin synthase gene gene837 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00838 S100027_00839 S100027_00839 bioI bioI 825957 827153 + Pimeloyl-[acyl-carrier protein] synthase Biotin biosynthesis%3B Disulfide bond%3B Heme%3B Iron%3B Metal-binding%3B Monooxygenase%3B Oxidoreductase%3B Catalyzes the C-C bond cleavage of fatty acid linked to acyl carrier protein (ACP) to generate pimelic acid for biotin biosynthesis. It has high affinity for long-chain fatty acids with the greatest affinity for myristic acid%3B Belongs to the cytochrome P450 family%3B KEGG: bli:BL00957 pimeloyl-(acyl-carrier protein) synthase gene gene838 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00839 S100027_00840 S100027_00840 S100027_00840 827196 828026 - Sodium channel protein 1 brain Glycoprotein%3B Ion channel%3B Ion transport%3B Membrane%3B Phosphoprotein%3B Repeat%3B Sodium%3B Sodium channel%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Voltage-gated channel%3B Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane%2C the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. Belongs to the sodium channel (TC 1. A. 1. 10) family gene gene839 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00840 S100027_00841 S100027_00841 S100027_00841 828190 828612 + HTH-type transcriptional regulator YfmP DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Repressor of the yfmOP operon. A mutation in yfmP leads to overexpression of yfmO%2C probably causing a decrease in cellular copper that is eventually responsible for a reduced copper induction of copZA%3B Contains 1 HTH merR-type DNA-binding domain gene gene840 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00841 S100027_00842 S100027_00842 S100027_00842 828671 829855 + Multidrug efflux protein YfmO Cell membrane%3B Copper%3B Copper transport%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Acts to efflux copper or a copper complex. It is possible that YfmO could contribute to copper resistance%3B Belongs to the major facilitator superfamily gene gene841 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00842 S100027_00843 S100027_00843 ccmA ccmA 829898 831454 - Heme-transporting ATPase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Ion transport%3B Membrane%3B Nucleotide-binding%3B Transport%3B Zinc%3B Zinc transport%3B Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Zinc importer (TC 3. A. 1. 15. 5) family%3B Contains 1 ABC transporter domain%3B KEGG: etr:ETAE_2461 heme exporter protein A gene gene842 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00843 S100027_00844 S100027_00844 cshB cshB 831592 832722 + RNA helicase ATP-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Ribosome biogenesis%3B RNA-binding%3B A probable DEAD-box RNA helicase that plays a role in ribosomal 50S subunit assembly. May be a non-specific RNA helicase%3B Belongs to the DEAD box helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: ssu:SSU05_1739 ATP-dependent RNA helicase CshB gene gene843 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00844 S100027_00845 S100027_00845 S100027_00845 832766 833788 - Putative NADP-dependent oxidoreductase YfmJ Aromatic hydrocarbons catabolism%3B Detoxification%3B NADP%3B Oxidoreductase%3B Putative quinone oxidoreductase that may contribute to the degradation of aromatic compounds%3B Belongs to the NADP-dependent oxidoreductase L4BD family gene gene844 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00845 S100027_00846 S100027_00846 S100027_00846 833845 834228 - uncharacterized protein gene gene845 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00846 S100027_00847 S100027_00847 S100027_00847 834423 834770 + General stress protein 17M Stress response. gene gene846 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00847 S100027_00848 S100027_00848 S100027_00848 834880 836316 + Putative malate transporter YflS Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Might be a malate transporter. Belongs to the SLC13A/DASS transporter (TC 2. A. 47) family. DIT1 subfamily gene gene847 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00848 S100027_00849 S100027_00849 S100027_00849 836444 837022 + hypothetical protein gene gene848 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00849 S100027_00850 S100027_00850 gloB gloB 837069 837851 - Hydroxyacylglutathione hydrolase Hydrolase%3B Metal-binding%3B Zinc%3B Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family%3B KEGG: rha:RHA1_ro06806 hydroxyacylglutathione hydrolase gene gene849 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00850 S100027_00851 S100027_00851 S100027_00851 837954 838751 + putative metallo-hydrolase YflN Hydrolase%3B Metal-binding%3B Zinc%3B Belongs to the metallo-beta-lactamase superfamily gene gene850 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00851 S100027_00852 S100027_00852 S100027_00852 838960 840603 + putative carboxypeptidase Carboxypeptidase%3B Glycoprotein%3B Hydrolase%3B Protease%3B Secreted%3B Signal%3B Virulence%3B Extracellular metalloprotease that contributes to pathogenicity%3B Belongs to the peptidase M14 family gene gene851 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00852 S100027_00853 S100027_00853 S100027_00853 840732 841829 + Nitric-oxide synthase (NAD(P)H) Heme%3B Iron%3B Metal-binding%3B NAD%3B NADP%3B Oxidoreductase%3B Catalyzes the production of nitric oxide%3B Belongs to the NOS family. Bacterial NOS oxygenase subfamily%3B KEGG: bli:BL03064 nitric-oxide synthase%2C bacterial gene gene852 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00853 S100027_00854 S100027_00854 S100027_00854 841917 842555 - hypothetical protein gene gene853 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00854 S100027_00855 S100027_00855 S100027_00855 842552 842836 - HTH-type transcriptional regulator KmtR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Represses expression of Rv2025c and its own expression. Acts by binding to the promoter regions%3B Contains 1 HTH arsR-type DNA-binding domain gene gene854 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00855 S100027_00856 S100027_00856 acyP acyP 842943 843215 - Acylphosphatase Hydrolase%3B Belongs to the acylphosphatase family%3B Contains 1 acylphosphatase-like domain%3B KEGG: bsu:BSU07640 acylphosphatase gene gene855 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00856 S100027_00857 S100027_00857 S100027_00857 843327 843977 + uncharacterized protein Contains 1 MOSC domain gene gene856 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00857 S100027_00858 S100027_00858 S100027_00858 844204 844335 - uncharacterized protein gene gene857 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00858 S100027_00859 S100027_00859 S100027_00859 844467 844622 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene858 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00859 S100027_00860 S100027_00860 S100027_00860 844708 845460 - Methionyl aminopeptidase Aminopeptidase%3B Cytoplasm%3B Hydrolase%3B Metal-binding%3B Protease%3B Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-%2C Cys%2C Gly%2C Pro%2C Ser%2C Thr%2C or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed%3B Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily%3B KEGG: ara:Arad_3299 methionyl aminopeptidase gene gene859 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00860 S100027_00861 S100027_00861 ltaS ltaS 845585 847546 - Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase Cell membrane%3B Cell wall biogenesis/degradation%3B Manganese%3B Membrane%3B Metal-binding%3B Secreted%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate%2C a reaction that presumably uses phosphatidylglycerol (PG) as substrate%3B Belongs to the LTA synthase family%3B KEGG: bld:BLi00793 lipoteichoic acid synthase gene gene860 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00861 S100027_00862 S100027_00862 S100027_00862 847808 848194 + uncharacterized protein gene gene861 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00862 S100027_00863 S100027_00863 S100027_00863 848256 849668 + putative transporter YflA Cell membrane%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the sodium:alanine (SAF) symporter family gene gene862 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00863 S100027_00864 S100027_00864 treB treB 849857 851269 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Kinase%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in trehalose transport. Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bsu:BSU07800 PTS system%2C trehalose-specific IIB component gene gene863 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00864 S100027_00865 S100027_00865 treC treC 851333 853030 + Alpha%2Calpha-phosphotrehalase Cytoplasm%3B Glycosidase%3B Hydrolase%3B Belongs to the glycosyl hydrolase 13 family%3B KEGG: bli:BL03069 trehalose-6-phosphate hydrolase gene gene864 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00865 S100027_00866 S100027_00866 S100027_00866 853052 853768 + Trehalose operon transcriptional repressor DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Repressor for the trehalose operon (treP and treA). Binds trehalose-6-phosphate%2C which probably acts as an inducer. Contains 1 HTH gntR-type DNA-binding domain gene gene865 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00866 S100027_00867 S100027_00867 lpxA lpxA 853875 854567 + Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase Acyltransferase%3B Cytoplasm%3B Lipid A biosynthesis%3B Lipid biosynthesis%3B Lipid metabolism%3B Repeat%3B Transferase%3B Involved in the biosynthesis of lipid A%2C a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell%3B Belongs to the transferase hexapeptide repeat family. LpxA subfamily%3B KEGG: mvs:MVIS_3839 UDP-N-acetylglucosamine acyltransferase gene gene866 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00867 S100027_00868 S100027_00868 S100027_00868 854694 855992 + Collectin-12 Calcium%3B Coiled coil%3B Collagen%3B Disulfide bond%3B Lectin%3B Membrane%3B Metal-binding%3B Receptor%3B Repeat%3B Signal-anchor%3B Transmembrane%3B Transmembrane helix%3B Scavenger receptor that displays several functions associated with host defense. Binds to carbohydrates (By similarity)%3B Contains 1 C-type lectin domain%3B Contains 2 collagen-like domains gene gene867 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00868 S100027_00869 S100027_00869 S100027_00869 856212 860468 + Collagen alpha-2(I) chain Collagen%3B Extinct organism protein%3B Extracellular matrix%3B Hydroxylation%3B Pyrrolidone carboxylic acid%3B Repeat%3B Secreted%3B Type I collagen is a member of group I collagen (fibrillar forming collagen)%3B Belongs to the fibrillar collagen family%3B Contains 9 collagen-like domains gene gene868 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00869 S100027_00870 S100027_00870 S100027_00870 860659 861519 - putative transposase-like protein DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene869 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00870 S100027_00871 S100027_00871 S100027_00871 861489 861821 - hypothetical protein gene gene870 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00871 S100027_00872 S100027_00872 arnB arnB 861935 863026 - UDP-4-amino-4-deoxy-L-arabinose aminotransferase Aminotransferase%3B Lipopolysaccharide biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Catalyzes the synthesis of GDP-perosamine from GDP-4- keto-6-deoxy-D-mannose and L-glutamate. Can use only L-glutamate as amino donor%3B Belongs to the DegT/DnrJ/EryC1 family%3B KEGG: pam:PANA_4002 UDP-4-amino-4-deoxy-L-arabinose-oxoglutarate aminotransferase gene gene871 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00872 S100027_00873 S100027_00873 S100027_00873 863023 863565 - Maltose O-acetyltransferase Acyltransferase%3B Amino-acid biosynthesis%3B Diaminopimelate biosynthesis%3B Lysine biosynthesis%3B Repeat%3B Transferase%3B Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate%3B Belongs to the transferase hexapeptide repeat family. DapH subfamily%3B KEGG: vni:VIBNI_B1816 maltose O-acetyltransferase gene gene872 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00873 S100027_00874 S100027_00874 galE galE 863583 864557 - UDP-glucose 4-epimerase Cell wall biogenesis/degradation%3B Cytoplasm%3B Isomerase%3B Lyase%3B Multifunctional enzyme%3B NAD%3B NADP%3B Oxidoreductase%3B Ubl conjugation%3B Trifunctional enzyme involved in UDP-beta-L-rhamnose biosynthesis%2C a precursor of the primary cell wall components rhamnogalacturonan I (RG-I) and rhamnogalacturonan II (RG-II) (PubMed:14671019%2C PubMed:17190829%2C PubMed:19056285). Plays a major role in supplying UDP-rhamnose for flavonol biosynthesis (PubMed:18757557). Catalyzes the dehydration of UDP-glucose to form UDP-4-dehydro-6-deoxy-D-glucose followed by the epimerization of the C3' and C5' positions of UDP-4-dehydro-6-deoxy-D-glucose to form UDP-4-keto-beta-L-rhamnose and the reduction of UDP-4-keto- beta-L-rhamnose to yield UDP-beta-L-rhamnose (By similarity)%3B In the N-terminal sectio%3B belongs to the NAD(P)- dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily%3B In the C-terminal sectio%3B belongs to the dTDP-4- dehydrorhamnose reductase family%3B KEGG: blh:BaLi_c09080 UDP-glucose 4-epimerase gene gene873 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00874 S100027_00875 S100027_00875 S100027_00875 864624 865997 - hypothetical protein gene gene874 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00875 S100027_00876 S100027_00876 S100027_00876 866152 868395 - Putative teichuronic acid biosynthesis glycosyltransferase TuaG Cell wall biogenesis/degradation%3B Glycosyltransferase%3B Stress response%3B Transferase%3B Belongs to the glycosyltransferase 2 family gene gene875 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00876 S100027_00877 S100027_00877 S100027_00877 868590 869672 + TPR repeat-containing protein Repeat%3B TPR repeat%3B Contains 5 TPR repeats%3B KEGG: bcz:BCZK1105 null%3B Hexosyltransferases gene gene876 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00877 S100027_00878 S100027_00878 S100027_00878 869711 870904 + dTDP-3-amino-3%2C4%2C6-trideoxy-alpha-D-glucose transaminase Antibiotic biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Involved in the biosynthesis of dTDP-alpha-D-desosamine%2C a sugar found in several bacterial macrolide antibiotics. Catalyzes the reversible transfer of the amino group from L- glutamate to the C-3 position of dTDP-3-keto-4%2C6-deoxyglucose to yield dTDP-3-amino-3%2C4%2C6-trideoxyglucose%3B Belongs to the degT/dnrJ/eryC1 family%3B KEGG: csc:Csac_1802 null%3B Transaminases gene gene877 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00878 S100027_00879 S100027_00879 wlbA wlbA 870901 871965 + UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase NAD%3B Oxidoreductase%3B Catalyzes the NAD(+)-dependent oxidation of scyllo- inositol to 2%2C4%2C6/3%2C5-pentahydroxycyclohexanone (scyllo-inosose)%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: plu:plu4797 UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase gene gene878 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00879 S100027_00880 S100027_00880 wbpA wbpA 872051 873346 + UDP-N-acetylglucosamine 6-dehydrogenase NAD%3B Oxidoreductase%3B Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc)%2C reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA)%3B Belongs to the UDP-glucose/GDP-mannose dehydrogenase family%3B KEGG: blh:BaLi_c09140 UDP-N-acetyl-D-glucosamine dehydrogenase gene gene879 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00880 S100027_00881 S100027_00881 S100027_00881 873427 874338 + uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix. gene gene880 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00881 S100027_00882 S100027_00882 S100027_00882 874335 874727 - putative HTH-type transcriptional regulator YtcD DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH hxlR-type DNA-binding domain gene gene881 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00882 S100027_00883 S100027_00883 S100027_00883 874858 875541 + Putative NAD(P)H nitroreductase YfkO Flavoprotein%3B FMN%3B NAD%3B NADP%3B Oxidoreductase%3B Belongs to the nitroreductase family%3B KEGG: oih:OB3126 null%3B Oxidoreductases gene gene882 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00883 S100027_00884 S100027_00884 yfkN yfkN 875583 879881 - 2'%2C3'-cyclic-nucleotide 2'-phosphodiesterase Cell wall%3B Hydrolase%3B Metal-binding%3B Multifunctional enzyme%3B Nucleotide-binding%3B Peptidoglycan-anchor%3B Secreted%3B Signal%3B Catalyzes the release of inorganic phosphate from 2'%2C3'- cyclic nucleotides through consecutive 2'%2C3'-phosphodiesterase and 3'- (or 2') nucleotidase activities. Also possesses a 5'- nucleotidase activity. Does not catalyze the release of inorganic phosphate from 3'%2C5'-cyclic nucleotides. Probably plays a role in the cellular reprocessing of nucleotides present in the medium%2C under conditions of phosphate shortage%3B Belongs to the 5'-nucleotidase family%3B KEGG: bli:BL03110 2'%2C3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase / 5'-nucleotidase gene gene883 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00884 S100027_00885 S100027_00885 pfpI pfpI 880113 880628 + General stress protein Hydrolase%3B Protease%3B Stress response%3B Functions in the protection against aldehyde-stress%2C possibly by degrading damaged proteins%3B Belongs to the peptidase C56 family%3B Contains 1 PfpI endopeptidase domain%3B KEGG: eco:b3153 protease I%3B Glycosylases gene gene884 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00885 S100027_00886 S100027_00886 S100027_00886 880669 880884 - UPF0435 protein Belongs to the UPF0435 family gene gene885 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00886 S100027_00887 S100027_00887 S100027_00887 880974 882332 - Sodium/alanine symporter AgcS Amino-acid transport%3B Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably functions as a sodium/L- and D-alanine symporter for alanine uptake%3B Belongs to the sodium:alanine (SAF) symporter family gene gene886 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00887 S100027_00888 S100027_00888 S100027_00888 882516 882986 + Protein-tyrosine-phosphatase Cytoplasm%3B Hydrolase%3B Protein phosphatase%3B May contribute to dephosphorylation of 'Tyr-15' of cdc2. Belongs to the low molecular weight phosphotyrosine protein phosphatase family%3B KEGG: aat:D11S_0095 protein-tyrosine phosphatase gene gene887 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00888 S100027_00889 S100027_00889 S100027_00889 883008 883358 + uncharacterized protein Coiled coil%3B Signal. gene gene888 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00889 S100027_00890 S100027_00890 S100027_00890 883355 884170 + Putative ribonuclease-like protein YfkH Cell membrane%3B Exonuclease%3B Hydrolase%3B Membrane%3B Nuclease%3B Transmembrane%3B Transmembrane helix. gene gene889 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00890 S100027_00891 S100027_00891 S100027_00891 884219 884326 + hypothetical protein gene gene890 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00891 S100027_00892 S100027_00892 S100027_00892 884366 885544 - putative MFS-type transporter YfkF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene891 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00892 S100027_00893 S100027_00893 S100027_00893 885645 886025 + hypothetical protein gene gene892 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00893 S100027_00894 S100027_00894 S100027_00894 886130 887185 + Ca(2+)/H(+) antiporter ChaA Antiport%3B Calcium%3B Calcium transport%3B Cell membrane%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons. Does not transport sodium or potassium%3B Belongs to the sodium/potassium/calcium exchanger family. Cation/proton exchanger (CAX) (TC 2. A. 19. 2) subfamily gene gene893 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00894 S100027_00895 S100027_00895 S100027_00895 887252 888043 + uncharacterized protein Signal. gene gene894 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00895 S100027_00896 S100027_00896 S100027_00896 888072 889193 - Putative protein YfkA 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B S-adenosyl-L-methionine%3B Belongs to the radical SAM superfamily gene gene895 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00896 S100027_00897 S100027_00897 S100027_00897 889337 889522 + uncharacterized protein Coiled coil. gene gene896 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00897 S100027_00898 S100027_00898 S100027_00898 889628 890422 + Peptidoglycan-N-acetylmuramic acid deacetylase PdaA Cell wall biogenesis/degradation%3B Hydrolase%3B Metal-binding%3B Signal%3B Sporulation%3B Catalyzes the deacetylation of N-acetylmuramic acid (MurNAc) residues in glycan strands of peptidoglycan%2C leading to the formation of muramic delta-lactam residues in spore cortex%2C after transpeptidation of deacetylated muramic acid residues. PdaA probably carries out both deacetylation and lactam ring formation and requires the product of CwlD activity on peptidoglycan as a substrate. Is required for germination. Cannot use chitin oligomer (hexa-N-acetylchitohexaose) as a substrate%3B Belongs to the polysaccharide deacetylase family%3B KEGG: bld:BLi00827 peptidoglycan-N-acetylmuramic acid deacetylase%3B In linear amides gene gene897 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00898 S100027_00899 S100027_00899 gldA gldA 890599 891702 + Glycerol dehydrogenase Glycerol metabolism%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Zinc%3B Catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone (glycerone). Allows microorganisms to utilize glycerol as a source of carbon under anaerobic conditions. Is also able to use various diols as substrates%2C such as propan-1%2C2-diol%2C butan-2%2C3-diol%2C ethan-1%2C2-diol%2C and 3-mercapto-1%2C2- dihydroxypropane%3B Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: bli:BL03089 glycerol dehydrogenase gene gene898 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00899 S100027_00900 S100027_00900 S100027_00900 891887 892351 - hypothetical protein gene gene899 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00900 S100027_00901 S100027_00901 S100027_00901 892540 893499 - Putative metal ion transporter YfjQ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the CorA metal ion transporter (MIT) (TC 1. A. 35) family gene gene900 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00901 S100027_00902 S100027_00902 alkA alkA 893633 894496 + DNA-3-methyladenine glycosylase II DNA damage%3B DNA repair%3B Hydrolase%3B Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine%2C 3-methylguanine%2C 7-methylguanine%2C O2- methylthymine%2C and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions%3B Belongs to the alkylbase DNA glycosidase AlkA family%3B KEGG: bli:BL03090 DNA-3-methyladenine glycosylase II gene gene901 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00902 S100027_00903 S100027_00903 S100027_00903 894499 895905 + 23S rRNA (uracil(1939)-C(5))-methyltransferase Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family%3B Contains 1 TRAM domain%3B KEGG: bld:BLi00832 23S rRNA (uracil1939-C5)-methyltransferase gene gene902 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00903 S100027_00904 S100027_00904 S100027_00904 895955 896434 + uncharacterized protein gene gene903 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00904 S100027_00905 S100027_00905 S100027_00905 897001 897279 + hypothetical protein gene gene904 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00905 S100027_00906 S100027_00906 S100027_00906 897313 897564 + hypothetical protein gene gene905 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00906 S100027_00907 S100027_00907 S100027_00907 897566 898291 + uncharacterized protein gene gene906 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00907 S100027_00908 S100027_00908 S100027_00908 898321 898896 - putative HTH-type transcriptional regulator YvkB DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH tetR-type DNA-binding domain gene gene907 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00908 S100027_00909 S100027_00909 S100027_00909 899004 900200 + putative UDP-glucosyltransferase YdhE Glycosyltransferase%3B Transferase%3B Belongs to the UDP-glycosyltransferase family%3B KEGG: sma:SAV_945 dTDP-L-oleandrosyltransferase%3B Hexosyltransferases gene gene908 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00909 S100027_00910 S100027_00910 S100027_00910 900294 900614 + uncharacterized protein Signal. gene gene909 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00910 S100027_00911 S100027_00911 S100027_00911 900719 901921 + Putative niacin/nicotinamide transporter NaiP Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably involved in the uptake of amidated and deamidated forms of niacin. Increases the growth rate of E. coli that is unable to make niacin de nov%3B confers increased sensitivity to the toxic niacin analog 6-amino-nicotinamide to wild-type E. coli. There is probably another mechanism for niacin uptake. Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene910 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00911 S100027_00912 S100027_00912 S100027_00912 902415 903791 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Kinase%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Negatively regulates SacY activity by catalyzing its phosphorylation on 'His-99'%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system may be involved in sucrose transport%3B Negatively regulates SacY%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bli:BL00914 PTS system%2C sucrose-specific IIB component gene gene911 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00912 S100027_00913 S100027_00913 S100027_00913 903834 904676 + Levansucrase and sucrase synthesis operon antiterminator Activator%3B Phosphoprotein%3B Repeat%3B RNA-binding%3B Transcription%3B Transcription regulation%3B In the presence of sucrose%2C SacY is activated and prevents premature termination of transcription by binding to a RNA-antiterminator (RAT) sequence (partially overlapping with the terminator sequence) located upstream of the sacB gene. Formation of the SacY-RAT complex prevents alternative formation of the terminator%2C allowing transcription of the sacB gene. In the absence of sucrose%2C inhibition of SacY activity by SacX leads to termination of transcription%3B Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains gene gene912 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00913 S100027_00914 S100027_00914 cynT cynT 904710 905216 - Carbonate dehydratase Belongs to the beta-class carbonic anhydrase family%3B KEGG: pjd:Pjdr2_2595 carbonic anhydrase gene gene913 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00914 S100027_00915 S100027_00915 S100027_00915 905228 907849 - UPF0753 protein Belongs to the UPF0753 family gene gene914 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00915 S100027_00916 S100027_00916 ndhF ndhF 907846 909378 - NADH:ubiquinone reductase (H(+)-translocating) Cell membrane%3B Membrane%3B NAD%3B Oxidoreductase%3B Quinone%3B Transmembrane%3B Transmembrane helix%3B Belongs to the complex I subunit 5 family%3B KEGG: bli:BL00918 NAD(P)H-quinone oxidoreductase subunit 5 gene gene915 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00916 S100027_00917 S100027_00917 S100027_00917 909554 909928 - uncharacterized protein gene gene916 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00917 S100027_00918 S100027_00918 S100027_00918 910199 910750 - Protein DJ-1 like protein B Chloroplast%3B Plastid%3B Repeat%3B Stress response%3B Transit peptide%3B May be involved in oxidative stress response%3B Belongs to the peptidase C56 family%3B Contains 2 PfpI endopeptidase domains gene gene917 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00918 S100027_00919 S100027_00919 pdhA pdhA 910960 911934 + Pyruvate dehydrogenase (acetyl-transferring) Chloroplast%3B Glycolysis%3B Oxidoreductase%3B Plastid%3B Pyruvate%3B Thiamine pyrophosphate%3B Transit peptide%3B The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1)%2C dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity)%3B KEGG: bli:BL03012 pyruvate dehydrogenase E1 component alpha subunit gene gene918 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00919 S100027_00920 S100027_00920 pdhB pdhB 911956 912990 + Pyruvate dehydrogenase (acetyl-transferring) Acetoin catabolism%3B Oxidoreductase%3B Catalyzes the 2%2C6-dichlorophenolindophenol-dependent cleavage of acetoin into acetate and acetaldehyde%3B KEGG: bli:BL03013 pyruvate dehydrogenase E1 component beta subunit gene gene919 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00920 S100027_00921 S100027_00921 dlsT dlsT 913013 914146 + Dihydrolipoyllysine-residue succinyltransferase Acyltransferase%3B Lipoyl%3B Transferase%3B Tricarboxylic acid cycle%3B The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1)%2C dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity)%3B Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: hin:HI1661 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) gene gene920 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00921 S100027_00922 S100027_00922 pdhD pdhD 914165 915541 + Dihydrolipoyl dehydrogenase Acetoin catabolism%3B Cytoplasm%3B Disulfide bond%3B FAD%3B Flavoprotein%3B Glycolysis%3B NAD%3B Oxidoreductase%3B Redox-active center%3B Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: ype:YPO3917 dihydrolipoamide dehydrogenase gene gene921 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00922 S100027_00923 S100027_00923 S100027_00923 915644 917479 + Acetoin dehydrogenase operon transcriptional activator AcoR Activator%3B ATP-binding%3B DNA-binding%3B Nucleotide-binding%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Acts as a transcriptional activator of the acoABCL operon encoding the acetoin dehydrogenase complex%3B Contains 1 sigma-54 factor interaction domain gene gene922 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00923 S100027_00924 S100027_00924 S100027_00924 917476 917802 - UPF0060 membrane protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0060 family gene gene923 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00924 S100027_00925 S100027_00925 glvA glvA 917989 919338 + Maltose-6'-phosphate glucosidase Carbohydrate metabolism%3B Cobalt%3B Glycosidase%3B Hydrolase%3B Manganese%3B Metal-binding%3B NAD%3B Nickel%3B Is involved in the catabolism of alpha-glycosides accumulated via a phosphoenolpyruvate-dependent phosphotransferase system (PEP-PTS). Hydrolyzes a wide variety of 6-phospho-alpha-D- glucosides including maltose-6'-phosphate%2C isomaltose-6'- phosphate%2C maltitol-6-phosphate%2C trehalose-6-phosphate and the 6'- phosphorylated derivatives of the five linkage-isomeric alpha-D- glucosyl-D-fructoses: trehalulose-6'-phosphate%2C turanose-6'- phosphate%2C maltulose-6'-phosphate%2C leucrose-6'-phosphate%2C and palatinose-6'-phosphate. However%2C sucrose-6-phosphate is not a substrate for this enzyme%3B Belongs to the glycosyl hydrolase 4 family%3B KEGG: bli:BL03017 maltose-6'-phosphate glucosidase gene gene924 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00925 S100027_00926 S100027_00926 S100027_00926 919438 920217 + HTH-type transcriptional regulator GlvR Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Positive regulator of the glv operon expression%2C which consists of GlvA%2C GlvR and GlvC%3B Contains 1 HTH rpiR-type DNA-binding domain%3B Contains 1 SIS domain gene gene925 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00926 S100027_00927 S100027_00927 glvB glvB 920236 921825 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Kinase%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in maltose transport%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: cro:ROD_40441 PTS system%2C arbutin-like IIB component gene gene926 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00927 S100027_00928 S100027_00928 S100027_00928 921968 922546 - hypothetical protein gene gene927 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00928 S100027_00929 S100027_00929 S100027_00929 922652 923629 - hypothetical protein gene gene928 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00929 S100027_00930 S100027_00930 S100027_00930 923799 924137 - putative HTH-type transcriptional regulator YvaP DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH hxlR-type DNA-binding domain gene gene929 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00930 S100027_00931 S100027_00931 S100027_00931 924366 924809 + Putative oxidoreductase CatD Aromatic hydrocarbons catabolism%3B Cell membrane%3B Detoxification%3B Membrane%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Essential for growth and viability in the presence of catechol and probably involved in the detoxification of catechol%3B Belongs to the DoxX family gene gene930 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00931 S100027_00932 S100027_00932 catE catE 924781 925641 + Catechol 2%2C3-dioxygenase Aromatic hydrocarbons catabolism%3B Detoxification%3B Dioxygenase%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Involved in the meta cleavage of catechol to 2- hydroxymuconic semialdehyde. Essential for growth and viability in the presence of catechol and probably involved in the detoxification of catechol%3B Belongs to the extradiol ring-cleavage dioxygenase family%3B KEGG: bli:BL03021 catechol 2%2C3-dioxygenase gene gene931 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00932 S100027_00933 S100027_00933 xynD xynD 925797 927401 + Non-reducing end alpha-L-arabinofuranosidase Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Multifunctional enzyme%3B Polysaccharide degradation%3B Xylan degradation%3B Has a 1. 6-fold higher activity as an arabinosidase than as a beta-xylosidase when tested on the substrates nitrophenyl- beta-D-xylopyranoside and P-nitrophenyl-alpha-L-arabinofuranoside. Belongs to the glycosyl hydrolase 43 family%3B KEGG: tco:Theco_2848 arabinoxylan arabinofuranohydrolase gene gene932 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00933 S100027_00934 S100027_00934 xynB xynB 927391 928938 + Xylan 1%2C4-beta-xylosidase Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Periplasm%3B Polysaccharide degradation%3B Signal%3B Alpha-L-arabinofuranosidase involved in xyloglucan degradation by mediating the cleavage of terminal non-reducing alpha-L-arabinofuranoside residues in xyloglucan branches%2C converting the 'S' units to 'X' units%3B Belongs to the glycosyl hydrolase 43 family%3B KEGG: bli:BL03023 xylan 1%2C4-beta-xylosidase gene gene933 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00934 S100027_00935 S100027_00935 S100027_00935 928935 929780 - putative HTH-type transcriptional regulator YijO DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH araC/xylS-type DNA-binding domain gene gene934 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00935 S100027_00936 S100027_00936 S100027_00936 929831 931234 + Putative ABC transporter peptide-binding protein YtcQ Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Probably part of a binding-protein-dependent transport system%3B Belongs to the bacterial solute-binding protein 1 family gene gene935 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00936 S100027_00937 S100027_00937 nqo1 nqo1 931516 931935 + NAD(P)H dehydrogenase (quinone) Cytoplasm%3B FAD%3B Flavoprotein%3B NAD%3B NADP%3B Oxidoreductase%3B The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis%3B Belongs to the NAD(P)H dehydrogenase (quinone) family%3B KEGG: bli:BL03025 NAD(P)H dehydrogenase (quinone) gene gene936 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00937 S100027_00938 S100027_00938 nudF nudF 931932 932543 + ADP-ribose diphosphatase Hydrolase%3B Magnesium%3B Manganese%3B Metal-binding%3B Probably mediates the hydrolysis of some nucleoside diphosphate derivatives%3B Belongs to the Nudix hydrolase family%3B Contains 1 nudix hydrolase domain%3B KEGG: bcl:ABC0282 ADP-ribose pyrophosphatase gene gene937 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00938 S100027_00939 S100027_00939 S100027_00939 932558 933088 + Putative metal-dependent hydrolase Cytoplasm%3B Hydrolase%3B Metal-binding%3B Zinc%3B Possible metal-dependent hydrolase%3B Belongs to the metal hydrolase YfiT family gene gene938 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00939 S100027_00940 S100027_00940 mprF mprF 933276 935828 + Lysyltransferase Antibiotic resistance%3B Cell membrane%3B Lipid metabolism%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG)%2C which produces lysylphosphatidylglycerol (LPG)%2C one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects B. subtilis against its own CAMPs and against those produced by competiting microorganisms (bacteriocins). In fact%2C the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides%3B Belongs to the LPG synthase family%3B KEGG: bli:BL03028 phosphatidylglycerol lysyltransferase gene gene939 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00940 S100027_00941 S100027_00941 S100027_00941 935825 935956 + hypothetical protein gene gene940 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00941 S100027_00942 S100027_00942 S100027_00942 935943 936839 + Trans-2%2C3-dihydro-3-hydroxyanthranilate isomerase Isomerase%3B Belongs to the PhzF family%3B KEGG: rle:RL4013 trans-2%2C3-dihydro-3-hydroxyanthranilate isomerase gene gene941 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00942 S100027_00943 S100027_00943 bluB bluB 936939 937517 + 5%2C6-dimethylbenzimidazole synthase Flavoprotein%3B FMN%3B NAD%3B NADP%3B Oxidoreductase%3B Belongs to the nitroreductase family%3B KEGG: baci:B1NLA3E_15285 5%2C6-dimethylbenzimidazole synthase gene gene942 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00943 S100027_00944 S100027_00944 S100027_00944 937557 937751 - uncharacterized protein gene gene943 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00944 S100027_00945 S100027_00945 S100027_00945 937820 937933 - hypothetical protein gene gene944 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00945 S100027_00946 S100027_00946 S100027_00946 938000 938530 - Ribosomal-protein-alanine N-acetyltransferase KEGG: bce:BC4195 ribosomal-protein-alanine N-acetyltransferase gene gene945 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00946 S100027_00947 S100027_00947 S100027_00947 938797 939696 - Epimerase family protein YfhF Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily gene gene946 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00947 S100027_00948 S100027_00948 S100027_00948 939765 940556 + Regulatory protein RecX Cytoplasm%3B Modulates RecA activity%3B Belongs to the RecX family gene gene947 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00948 S100027_00949 S100027_00949 S100027_00949 940561 940875 + uncharacterized protein gene gene948 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00949 S100027_00950 S100027_00950 S100027_00950 940906 941076 - hypothetical protein gene gene949 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00950 S100027_00951 S100027_00951 S100027_00951 941103 941252 - Small%2C acid-soluble spore protein Sporulation%3B Belongs to the SspK family gene gene950 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00951 S100027_00952 S100027_00952 S100027_00952 941384 941653 + uncharacterized protein gene gene951 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00952 S100027_00953 S100027_00953 arnC arnC 942346 943305 + Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase Cell membrane%3B Glycosyltransferase%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Belongs to the glycosyltransferase 2 family. GtrB subfamily%3B KEGG: gme:Gmet_0885 undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase gene gene952 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00953 S100027_00954 S100027_00954 S100027_00954 943274 943675 + hypothetical protein gene gene953 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00954 S100027_00955 S100027_00955 S100027_00955 943672 946257 + uncharacterized protein Cell membrane%3B Coiled coil%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene954 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00955 S100027_00956 S100027_00956 S100027_00956 946254 947237 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B May act as a negative regulator for the transcription of yfhQ%2C fabL%2C sspE and yfhP gene gene955 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00956 S100027_00957 S100027_00957 mutY mutY 947445 948530 + putative A/G-specific adenine glycosylase YfhQ 4Fe-4S%3B DNA damage%3B DNA repair%3B Glycosidase%3B Hydrolase%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7%2C8-dihydro-8-oxoguanine%2C 8- oxo-dGTP) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A. T to G. C transversions (By similarity). Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7%2C8-dihydro-8- oxoguanine (By similarity)%3B Belongs to the Nth/MutY family%3B Contains 1 HhH domain%3B KEGG: bli:BL03038 A/G-specific adenine glycosylase%3B Hydrolyzing N-glycosyl compounds gene gene956 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00957 S100027_00958 S100027_00958 S100027_00958 948556 948780 - uncharacterized protein gene gene957 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00958 S100027_00959 S100027_00959 phbB phbB 948863 949615 + Acetoacetyl-CoA reductase Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B NADP%3B Oxidoreductase%3B Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). It confers resistance to triclosan%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: jag:GJA_3696 acetoacetyl-CoA reductase gene gene958 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00959 S100027_00960 S100027_00960 S100027_00960 949684 949848 + Small%2C acid-soluble spore protein gamma-type Repeat%3B Sporulation%3B SASP are proteins degraded in the first minutes of spore germination and provide amino acids for both new protein synthesis and metabolism. These proteins may be involved in dormant spore's high resistance to UV light. Belongs to the gamma-type SASP family gene gene959 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00960 S100027_00961 S100027_00961 S100027_00961 950016 950261 + uncharacterized protein Coiled coil. gene gene960 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00961 S100027_00962 S100027_00962 S100027_00962 950425 950955 + UPF0374 protein Belongs to the UPF0374 family gene gene961 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00962 S100027_00963 S100027_00963 msbA msbA 951031 952773 + Putative multidrug export ATP-binding/permease protein YgaD ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B May be involved in multidrug export. Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain%3B KEGG: bsu:BSU08690 ATP-binding cassette%2C subfamily B%2C bacterial MsbA%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene962 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00963 S100027_00964 S100027_00964 S100027_00964 952904 953884 + Oligopeptide transport ATP-binding protein OppD ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Peptide transport%3B Protein transport%3B Transport%3B Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene963 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00964 S100027_00965 S100027_00965 S100027_00965 953881 954837 + Macrolide export ATP-binding/permease protein MacB Antibiotic resistance%3B ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD)%2C which form a pore in the inner membrane%2C and an ATP-binding domain (NBD)%2C which is responsible for energy generation. Confers resistance against macrolides%3B Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3. A. 1. 122) family%3B Contains 1 ABC transporter domain gene gene964 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00965 S100027_00966 S100027_00966 S100027_00966 954834 956432 + Periplasmic dipeptide transport protein Chemotaxis%3B Disulfide bond%3B Peptide transport%3B Periplasm%3B Protein transport%3B Signal%3B Transport%3B Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis. Belongs to the bacterial solute-binding protein 5 family gene gene965 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00966 S100027_00967 S100027_00967 S100027_00967 956446 957447 + Oligopeptide transport system permease protein AppB Cell membrane%3B Competence%3B Membrane%3B Peptide transport%3B Protein transport%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence%2C though%2C unlike OPP%2C is incapable of transporting tripeptides. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene966 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00967 S100027_00968 S100027_00968 S100027_00968 957460 958350 + putative D%2CD-dipeptide transport system permease protein DdpC Cell inner membrane%3B Cell membrane%3B Membrane%3B Peptide transport%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex DdpABCDF%2C which is probably involved in D%2CD-dipeptide transport. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene967 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00968 S100027_00969 S100027_00969 S100027_00969 958380 959450 - UPF0421 protein YgaE Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0421 family gene gene968 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00969 S100027_00970 S100027_00970 hemL hemL 959703 961001 - Glutamate-1-semialdehyde 2%2C1-aminomutase Cytoplasm%3B Isomerase%3B Porphyrin biosynthesis%3B Pyridoxal phosphate%3B Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily%3B KEGG: bli:BL03060 glutamate-1-semialdehyde 2%2C1-aminomutase gene gene969 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00970 S100027_00971 S100027_00971 prxQ prxQ 961165 961638 + Peroxiredoxin Oxidoreductase%3B Peroxidase%3B Redox-active center%3B Belongs to the AhpC/TSA family%3B Contains 1 thioredoxin domain%3B KEGG: cbu:CBU_0963 peroxiredoxin Q/BCP gene gene970 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00971 S100027_00972 S100027_00972 S100027_00972 961851 962288 + Peroxide operon regulator Cytoplasm%3B Disulfide bond%3B DNA-binding%3B Manganese%3B Metal-binding%3B Oxidation%3B Repressor%3B Transcription%3B Transcription regulation%3B Zinc%3B Hydrogen and organic peroxide sensor. Represses the expression of a regulon of peroxide-inducible genes such as katA%2C ahpC%2C ahpF%2C the heme biosynthesis operon (hemAXCDBL)%2C fur%2C perR%2C zosA and mrgA. Belongs to the Fur family gene gene971 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00972 S100027_00973 S100027_00973 S100027_00973 962337 962684 - UPF0295 protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0295 family gene gene972 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00973 S100027_00974 S100027_00974 S100027_00974 962902 963786 + uncharacterized protein gene gene973 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00974 S100027_00975 S100027_00975 S100027_00975 964074 965623 + 16S ribosomal RNA rRNA gene974 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00975 S100027_00976 S100027_00976 S100027_00976 965798 968728 + 23S ribosomal RNA rRNA gene975 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00976 S100027_00977 S100027_00977 S100027_00977 968899 969014 + 5S ribosomal RNA rRNA gene976 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00977 S100027_00978 S100027_00978 S100027_00978 969024 969098 + tRNA-Asn tRNA gene977 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00978 S100027_00979 S100027_00979 S100027_00979 969105 969196 + tRNA-Ser tRNA gene978 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00979 S100027_00980 S100027_00980 S100027_00980 969211 969285 + tRNA-Glu tRNA gene979 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00980 S100027_00981 S100027_00981 S100027_00981 969403 969478 + tRNA-Val tRNA gene980 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00981 S100027_00982 S100027_00982 S100027_00982 969500 969576 + tRNA-Met tRNA gene981 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00982 S100027_00983 S100027_00983 S100027_00983 969591 969667 + tRNA-Asp tRNA gene982 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00983 S100027_00984 S100027_00984 S100027_00984 969678 969753 + tRNA-Phe tRNA gene983 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00984 S100027_00985 S100027_00985 S100027_00985 969757 969829 + tRNA-Thr tRNA gene984 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00985 S100027_00986 S100027_00986 S100027_00986 969837 969921 + tRNA-Tyr tRNA gene985 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00986 S100027_00987 S100027_00987 S100027_00987 969929 970002 + tRNA-Trp tRNA gene986 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00987 S100027_00988 S100027_00988 S100027_00988 970023 970095 + tRNA-His tRNA gene987 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00988 S100027_00989 S100027_00989 S100027_00989 970104 970175 + tRNA-Gln tRNA gene988 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00989 S100027_00990 S100027_00990 S100027_00990 970229 970303 + tRNA-Gly tRNA gene989 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00990 S100027_00991 S100027_00991 S100027_00991 970317 970387 + tRNA-Cys tRNA gene990 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00991 S100027_00992 S100027_00992 S100027_00992 970398 970486 + tRNA-Leu tRNA gene991 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00992 S100027_00993 S100027_00993 S100027_00993 970672 971631 + Tyrosine recombinase XerC Cell cycle%3B Cell division%3B Chromosome partition%3B Cytoplasm%3B DNA integration%3B DNA recombination%3B DNA-binding%3B Site-specific tyrosine recombinase%2C which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids%3B Belongs to the 'phage' integrase family. XerC subfamily gene gene992 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00993 S100027_00994 S100027_00994 S100027_00994 971891 972820 + hypothetical protein gene gene993 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00994 S100027_00995 S100027_00995 S100027_00995 972837 973211 + hypothetical protein gene gene994 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00995 S100027_00996 S100027_00996 S100027_00996 973406 973753 + hypothetical protein gene gene995 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00996 S100027_00997 S100027_00997 S100027_00997 973731 973919 + hypothetical protein gene gene996 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00997 S100027_00998 S100027_00998 S100027_00998 973919 974242 + hypothetical protein gene gene997 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00998 S100027_00999 S100027_00999 S100027_00999 974417 974752 + hypothetical protein gene gene998 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_00999 S100027_01000 S100027_01000 S100027_01000 974749 974994 + hypothetical protein gene gene999 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01000 S100027_01001 S100027_01001 S100027_01001 974994 975167 + hypothetical protein gene gene1000 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01001 S100027_01002 S100027_01002 S100027_01002 975168 975494 + hypothetical protein gene gene1001 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01002 S100027_01003 S100027_01003 S100027_01003 975494 975862 + hypothetical protein gene gene1002 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01003 S100027_01004 S100027_01004 S100027_01004 975846 976229 + hypothetical protein gene gene1003 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01004 S100027_01005 S100027_01005 S100027_01005 976246 976641 + hypothetical protein gene gene1004 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01005 S100027_01006 S100027_01006 S100027_01006 976634 976840 + hypothetical protein gene gene1005 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01006 S100027_01007 S100027_01007 S100027_01007 976837 976983 + hypothetical protein gene gene1006 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01007 S100027_01008 S100027_01008 S100027_01008 977002 977796 + hypothetical protein gene gene1007 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01008 S100027_01009 S100027_01009 S100027_01009 977766 978266 + hypothetical protein gene gene1008 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01009 S100027_01010 S100027_01010 S100027_01010 978266 978469 + hypothetical protein gene gene1009 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01010 S100027_01011 S100027_01011 dnaB dnaB 978466 979815 + DNA helicase KEGG: bao:BAMF_0894 replicative DNA helicase gene gene1010 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01011 S100027_01012 S100027_01012 S100027_01012 979837 980856 + hypothetical protein gene gene1011 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01012 S100027_01013 S100027_01013 S100027_01013 981154 981351 - hypothetical protein gene gene1012 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01013 S100027_01014 S100027_01014 S100027_01014 981460 982638 + hypothetical protein gene gene1013 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01014 S100027_01015 S100027_01015 S100027_01015 982914 983528 + hypothetical protein gene gene1014 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01015 S100027_01016 S100027_01016 S100027_01016 983665 983817 + hypothetical protein gene gene1015 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01016 S100027_01017 S100027_01017 S100027_01017 983814 984338 + hypothetical protein gene gene1016 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01017 S100027_01018 S100027_01018 S100027_01018 984586 985341 + hypothetical protein gene gene1017 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01018 S100027_01019 S100027_01019 S100027_01019 985365 985796 + hypothetical protein gene gene1018 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01019 S100027_01020 S100027_01020 S100027_01020 985837 986916 + hypothetical protein gene gene1019 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01020 S100027_01021 S100027_01021 dpo1 dpo1 987122 989419 + DNA-directed DNA polymerase DNA damage%3B DNA repair%3B DNA replication%3B DNA-binding%3B DNA-directed DNA polymerase%3B Exonuclease%3B Hydrolase%3B Nuclease%3B Nucleotidyltransferase%3B Transferase%3B In addition to polymerase activity%2C this DNA polymerase exhibits 3' to 5' and 5' to 3' exonuclease activity. It is able to utilize nicked circular duplex DNA as a template and can unwind the parental DNA strand from its template. Belongs to the DNA polymerase type-A family%3B Contains 1 3'-5' exonuclease domain%3B Contains 1 5'-3' exonuclease domain%3B KEGG: bao:BAMF_0904 DNA polymerase I gene gene1020 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01021 S100027_01022 S100027_01022 S100027_01022 989420 990469 + hypothetical protein gene gene1021 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01022 S100027_01023 S100027_01023 S100027_01023 990469 990789 + hypothetical protein gene gene1022 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01023 S100027_01024 S100027_01024 ruvC ruvC 990786 991304 + Crossover junction endodeoxyribonuclease KEGG: bao:BAMF_0908 crossover junction endodeoxyribonuclease RuvC gene gene1023 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01024 S100027_01025 S100027_01025 S100027_01025 991310 991675 + hypothetical protein gene gene1024 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01025 S100027_01026 S100027_01026 S100027_01026 991680 991937 + hypothetical protein gene gene1025 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01026 S100027_01027 S100027_01027 S100027_01027 991934 992128 + hypothetical protein gene gene1026 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01027 S100027_01028 S100027_01028 S100027_01028 992125 992325 + hypothetical protein gene gene1027 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01028 S100027_01029 S100027_01029 S100027_01029 992322 992471 + hypothetical protein gene gene1028 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01029 S100027_01030 S100027_01030 S100027_01030 992465 992827 + Protein NrdI Probably involved in ribonucleotide reductase function%3B Belongs to the NrdI family gene gene1029 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01030 S100027_01031 S100027_01031 nrdA nrdA 992834 994933 + Ribonucleoside-diphosphate reductase Allosteric enzyme%3B ATP-binding%3B Disulfide bond%3B DNA replication%3B Nucleotide-binding%3B Oxidoreductase%3B Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase large chain family%3B KEGG: bao:BAMF_0912 ribonucleoside-diphosphate reductase alpha chain gene gene1030 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01031 S100027_01032 S100027_01032 S100027_01032 994965 995297 + hypothetical protein gene gene1031 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01032 S100027_01033 S100027_01033 nrdB nrdB 995336 996304 + Ribonucleoside-diphosphate reductase DNA replication%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase small chain family%3B KEGG: bamy:V529_20170 ribonucleoside-diphosphate reductase beta chain gene gene1032 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01033 S100027_01034 S100027_01034 S100027_01034 996355 996936 + dUTP diphosphatase Hydrolase%3B Magnesium%3B Metal-binding%3B Nucleotide metabolism%3B This enzyme is involved in nucleotide metabolism: it produces dUMP%2C the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA%3B Belongs to the dUTPase family%3B KEGG: bao:BAMF_0916 dUTP pyrophosphatase gene gene1033 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01034 S100027_01035 S100027_01035 S100027_01035 996936 997163 + hypothetical protein gene gene1034 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01035 S100027_01036 S100027_01036 S100027_01036 997164 997334 + hypothetical protein gene gene1035 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01036 S100027_01037 S100027_01037 S100027_01037 997555 997896 + SPBc2 prophage-derived uncharacterized protein YorM Signal. gene gene1036 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01037 S100027_01038 S100027_01038 S100027_01038 997912 998976 + uncharacterized protein gene gene1037 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01038 S100027_01039 S100027_01039 S100027_01039 998973 999533 + hypothetical protein gene gene1038 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01039 S100027_01040 S100027_01040 S100027_01040 999522 999908 - hypothetical protein gene gene1039 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01040 S100027_01041 S100027_01041 S100027_01041 1000019 1001293 + Site-specific DNA-methyltransferase (adenine-specific) KEGG: ftd:AS84_1540 type I restriction enzyme M protein gene gene1040 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01041 S100027_01042 S100027_01042 S100027_01042 1001293 1001682 + hypothetical protein gene gene1041 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01042 S100027_01043 S100027_01043 S100027_01043 1001675 1002163 + hypothetical protein gene gene1042 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01043 S100027_01044 S100027_01044 S100027_01044 1002252 1003052 + hypothetical protein gene gene1043 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01044 S100027_01045 S100027_01045 S100027_01045 1003085 1003396 - hypothetical protein gene gene1044 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01045 S100027_01046 S100027_01046 S100027_01046 1003408 1004835 - hypothetical protein gene gene1045 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01046 S100027_01047 S100027_01047 S100027_01047 1004886 1005230 + hypothetical protein gene gene1046 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01047 S100027_01048 S100027_01048 S100027_01048 1005367 1005585 + hypothetical protein gene gene1047 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01048 S100027_01049 S100027_01049 S100027_01049 1006571 1006849 + hypothetical protein gene gene1048 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01049 S100027_01050 S100027_01050 S100027_01050 1006839 1007213 + hypothetical protein gene gene1049 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01050 S100027_01051 S100027_01051 S100027_01051 1007206 1007754 + hypothetical protein gene gene1050 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01051 S100027_01052 S100027_01052 S100027_01052 1007755 1008144 + hypothetical protein gene gene1051 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01052 S100027_01053 S100027_01053 S100027_01053 1008461 1008760 + hypothetical protein gene gene1052 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01053 S100027_01054 S100027_01054 S100027_01054 1008763 1009005 + hypothetical protein gene gene1053 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01054 S100027_01055 S100027_01055 S100027_01055 1009171 1009509 + hypothetical protein gene gene1054 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01055 S100027_01056 S100027_01056 S100027_01056 1009629 1009952 + hypothetical protein gene gene1055 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01056 S100027_01057 S100027_01057 S100027_01057 1009927 1011708 + Putative terminase large subunit Viral genome packaging%3B Virus exit from host cell%3B Belongs to the phage terminase family gene gene1056 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01057 S100027_01058 S100027_01058 S100027_01058 1011720 1013018 + hypothetical protein gene gene1057 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01058 S100027_01059 S100027_01059 clpP clpP 1012972 1013718 + Endopeptidase Clp Cytoplasm%3B Hydrolase%3B Protease%3B Serine protease%3B Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins%3B Belongs to the peptidase S14 family%3B KEGG: bli:BL00880 ATP-dependent Clp protease%2C protease subunit gene gene1058 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01059 S100027_01060 S100027_01060 S100027_01060 1013718 1014872 + hypothetical protein gene gene1059 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01060 S100027_01061 S100027_01061 S100027_01061 1014913 1015410 + Chitinase Carbohydrate metabolism%3B Chitin degradation%3B Chitin-binding%3B Glycosidase%3B Hydrolase%3B Polysaccharide degradation%3B Signal%3B Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily%3B Contains 1 CBM2 (carbohydrate binding type-2) domain%3B Contains 1 fibronectin type-III domain gene gene1060 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01061 S100027_01062 S100027_01062 S100027_01062 1015413 1015652 + hypothetical protein gene gene1061 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01062 S100027_01063 S100027_01063 S100027_01063 1015657 1015992 + hypothetical protein gene gene1062 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01063 S100027_01064 S100027_01064 S100027_01064 1015989 1016411 + hypothetical protein gene gene1063 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01064 S100027_01065 S100027_01065 S100027_01065 1016429 1016752 + hypothetical protein gene gene1064 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01065 S100027_01066 S100027_01066 S100027_01066 1016761 1017342 + hypothetical protein gene gene1065 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01066 S100027_01067 S100027_01067 S100027_01067 1017293 1017607 + hypothetical protein gene gene1066 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01067 S100027_01068 S100027_01068 S100027_01068 1017658 1017993 + hypothetical protein gene gene1067 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01068 S100027_01069 S100027_01069 S100027_01069 1018236 1023536 + Tape measure protein Host membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Viral tail assembly%3B Virus exit from host cell%3B Plays a role in virion tail formation. The length of the tape measure protein is proportional to the length of the phage's tail gene gene1068 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01069 S100027_01070 S100027_01070 S100027_01070 1023537 1024358 + hypothetical protein gene gene1069 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01070 S100027_01071 S100027_01071 S100027_01071 1024368 1025894 + hypothetical protein gene gene1070 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01071 S100027_01072 S100027_01072 S100027_01072 1025937 1027985 + hypothetical protein gene gene1071 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01072 S100027_01073 S100027_01073 S100027_01073 1028006 1029067 + Phage-like element PBSX protein XkdV To B. subtilis YqcC gene gene1072 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01073 S100027_01074 S100027_01074 S100027_01074 1029158 1029445 + SPBc2 prophage-derived uncharacterized protein YomR Coiled coil. gene gene1073 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01074 S100027_01075 S100027_01075 S100027_01075 1029458 1029754 + hypothetical protein gene gene1074 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01075 S100027_01076 S100027_01076 S100027_01076 1029755 1029949 + hypothetical protein gene gene1075 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01076 S100027_01077 S100027_01077 S100027_01077 1029953 1030216 + hypothetical protein gene gene1076 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01077 S100027_01078 S100027_01078 S100027_01078 1030283 1031218 + N-acetylmuramoyl-L-alanine amidase Cell wall biogenesis/degradation%3B Competence%3B Hydrolase%3B Secreted%3B Signal%3B Sporulation%3B Autolysins are involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella and sporulation%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B Contains 1 LysM repeat%3B KEGG: bli:BL00542 N-acetylmuramoyl-L-alanine amidase gene gene1077 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01078 S100027_01079 S100027_01079 S100027_01079 1031240 1031497 + hypothetical protein gene gene1078 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01079 S100027_01080 S100027_01080 S100027_01080 1031586 1031903 + hypothetical protein gene gene1079 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01080 S100027_01081 S100027_01081 S100027_01081 1031941 1032207 - hypothetical protein gene gene1080 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01081 S100027_01082 S100027_01082 tagE tagE 1032228 1033742 - Poly(glycerol-phosphate) alpha-glucosyltransferase Cell inner membrane%3B Cell membrane%3B Glycosyltransferase%3B Membrane%3B Transferase%3B Adds a GalNAc residue on to the Und-PP-Bac2%2C4diNAc- GalNAc disaccharide in the N-linked protein glycosylation pathway. Transfers the third sugar in the heptasaccharide biosynthesis%3B Belongs to the glycosyltransferase group 1 family%3B KEGG: bso:BSNT_02005 poly(glycerol-phosphate) alpha-glucosyltransferase gene gene1081 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01082 S100027_01083 S100027_01083 S100027_01083 1033806 1034021 - hypothetical protein gene gene1082 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01083 S100027_01084 S100027_01084 S100027_01084 1034181 1034999 + hypothetical protein gene gene1083 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01084 S100027_01085 S100027_01085 S100027_01085 1035072 1035401 + hypothetical protein gene gene1084 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01085 S100027_01086 S100027_01086 S100027_01086 1035706 1035790 + tRNA-Leu tRNA gene1085 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01086 S100027_01087 S100027_01087 rapD rapD 1036117 1036395 + Response regulator aspartate phosphatase Hydrolase%3B Protein phosphatase%3B Repeat%3B TPR repeat%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bli:BL02513 response regulator aspartate phosphatase D%3B Acting on ester bonds gene gene1086 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01087 S100027_01088 S100027_01088 S100027_01088 1036615 1037085 + Response regulator aspartate phosphatase D Hydrolase%3B Protein phosphatase%3B Repeat%3B TPR repeat%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bli:BL02513 response regulator aspartate phosphatase D%3B Acting on ester bonds gene gene1087 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01088 S100027_01089 S100027_01089 S100027_01089 1037140 1037277 + hypothetical protein gene gene1088 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01089 S100027_01090 S100027_01090 S100027_01090 1039618 1039833 + hypothetical protein gene gene1089 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01090 S100027_01091 S100027_01091 S100027_01091 1039806 1040177 + N-acetylmuramoyl-L-alanine amidase Cell wall biogenesis/degradation%3B Hydrolase%3B Repeat%3B Secreted%3B Signal%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B KEGG: bli:BL01582 N-acetylmuramoyl-L-alanine amidase gene gene1090 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01091 S100027_01092 S100027_01092 S100027_01092 1040236 1040574 - hypothetical protein gene gene1091 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01092 S100027_01093 S100027_01093 S100027_01093 1040600 1042324 - Ribonuclease YxiD Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene1092 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01093 S100027_01094 S100027_01094 S100027_01094 1042590 1042886 + hypothetical protein gene gene1093 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01094 S100027_01095 S100027_01095 S100027_01095 1043117 1043557 - hypothetical protein gene gene1094 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01095 S100027_01096 S100027_01096 S100027_01096 1043574 1044482 - hypothetical protein gene gene1095 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01096 S100027_01097 S100027_01097 S100027_01097 1044530 1045132 - Ribonuclease YxiD Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene1096 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01097 S100027_01098 S100027_01098 rapE rapE 1045458 1046648 + Response regulator aspartate phosphatase Hydrolase%3B Protein phosphatase%3B Repeat%3B Sporulation%3B TPR repeat%3B Prevents sporulation by dephosphorylating Spo0F%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bli:BL01908 response regulator aspartate phosphatase E%3B Acting on ester bonds gene gene1097 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01098 S100027_01099 S100027_01099 S100027_01099 1047209 1048639 - hypothetical protein gene gene1098 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01099 S100027_01100 S100027_01100 tarS tarS 1048917 1050242 + Threonine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B Zinc%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: pod:PODO_08475 threonyl-tRNA synthetase gene gene1099 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01100 S100027_01101 S100027_01101 aroD aroD 1051095 1051859 + 3-dehydroquinate dehydratase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Lyase%3B Schiff base%3B Involved in the third step of the chorismate pathway%2C which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate%3B Belongs to the type-I 3-dehydroquinase family%3B KEGG: bli:BL00001 3-dehydroquinate dehydratase I gene gene1100 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01101 S100027_01102 S100027_01102 thiC thiC 1052265 1054040 + Phosphomethylpyrimidine synthase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Lyase%3B Metal-binding%3B S-adenosyl-L-methionine%3B Thiamine biosynthesis%3B Zinc%3B Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction%3B Belongs to the ThiC family%3B KEGG: bsu:BSU08790 phosphomethylpyrimidine synthase gene gene1101 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01102 S100027_01103 S100027_01103 ssuB ssuB 1054243 1055010 + Aliphatic sulfonates import ATP-binding protein SsuB ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3. A. 1. 17. 2) family%3B Contains 1 ABC transporter domain%3B KEGG: bli:BL03206 sulfonate transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene1102 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01103 S100027_01104 S100027_01104 S100027_01104 1055031 1056020 + Putative aliphatic sulfonates-binding protein Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B Part of a binding-protein-dependent transport system for aliphatic sulfonates. Putative binding protein. Belongs to the bacterial solute-binding protein SsuA/TauA family gene gene1103 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01104 S100027_01105 S100027_01105 S100027_01105 1056017 1056853 + Putative aliphatic sulfonates transport permease protein SsuC Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of a binding-protein-dependent transport system for aliphatic sulfonates. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1104 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01105 S100027_01106 S100027_01106 ssuD ssuD 1056867 1057997 + Alkanesulfonate monooxygenase Flavoprotein%3B FMN%3B Monooxygenase%3B Oxidoreductase%3B Catalyzes the desulfonation of aliphatic sulfonates%3B Belongs to the SsuD family%3B KEGG: rme:Rmet_1371 alkanesulfonate monooxygenase gene gene1105 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01106 S100027_01107 S100027_01107 S100027_01107 1058028 1058486 - putative lipoprotein YgaO Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transmembrane%3B Transmembrane helix. gene gene1106 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01107 S100027_01108 S100027_01108 S100027_01108 1058483 1058689 - putative HTH-type transcriptional regulator YgzD DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene1107 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01108 S100027_01109 S100027_01109 S100027_01109 1059239 1059451 + hypothetical protein gene gene1108 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01109 S100027_01110 S100027_01110 potA potA 1059559 1060305 + Polyamine-transporting ATPase Amino-acid transport%3B ATP-binding%3B CBS domain%3B Nucleotide-binding%3B Repeat%3B Transport%3B Involved in a high affinity multicomponent binding- protein-dependent transport system for choline. Probably responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B Contains 2 CBS domains%3B KEGG: pkc:PKB_2225 spermidine/putrescine transport system ATP-binding protein gene gene1109 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01110 S100027_01111 S100027_01111 S100027_01111 1060271 1061740 + hypothetical protein gene gene1110 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01111 S100027_01112 S100027_01112 S100027_01112 1061730 1062638 + hypothetical protein gene gene1111 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01112 S100027_01113 S100027_01113 S100027_01113 1062635 1062919 + hypothetical protein gene gene1112 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01113 S100027_01114 S100027_01114 S100027_01114 1063027 1063296 + 30S ribosomal protein S14 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Binds 16S rRNA%2C required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site%3B Belongs to the ribosomal protein S14P family gene gene1113 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01114 S100027_01115 S100027_01115 S100027_01115 1063439 1063512 + tRNA-Gly tRNA gene1114 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01115 S100027_01116 S100027_01116 S100027_01116 1063621 1064250 - uncharacterized protein gene gene1115 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01116 S100027_01117 S100027_01117 queG queG 1064331 1065479 + Epoxyqueuosine reductase 4Fe-4S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase%3B Queuosine biosynthesis%3B Repeat%3B tRNA processing%3B Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q)%2C which is a hypermodified base found in the wobble positions of tRNA(Asp)%2C tRNA(Asn)%2C tRNA(His) and tRNA(Tyr)%3B Belongs to the QueG family%3B Contains 2 4Fe-4S ferredoxin-type domains%3B KEGG: bli:BL03196 epoxyqueuosine reductase gene gene1116 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01117 S100027_01118 S100027_01118 S100027_01118 1065543 1066448 + uncharacterized protein gene gene1117 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01118 S100027_01119 S100027_01119 trmL trmL 1066492 1066965 + tRNA (cytidine(34)-2'-O)-methyltransferase Cytoplasm%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B tRNA processing%3B Could methylate the ribose at the nucleotide 34 wobble position in tRNA%3B Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily%3B KEGG: gpb:HDN1F_07340 tRNA (cytidine/uridine-2'-O-)-methyltransferase gene gene1118 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01119 S100027_01120 S100027_01120 S100027_01120 1067057 1067671 + uncharacterized protein gene gene1119 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01120 S100027_01121 S100027_01121 S100027_01121 1067686 1068396 + uncharacterized protein gene gene1120 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01121 S100027_01122 S100027_01122 S100027_01122 1068411 1069112 + uncharacterized protein gene gene1121 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01122 S100027_01123 S100027_01123 S100027_01123 1069513 1071408 + Protein PrkA Belongs to the PrkA family gene gene1122 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01123 S100027_01124 S100027_01124 S100027_01124 1071583 1072749 + Stress response UPF0229 protein YhbH Stress response%3B Belongs to the UPF0229 family gene gene1123 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01124 S100027_01125 S100027_01125 S100027_01125 1073057 1073689 + Putative efflux system component YhbJ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene1124 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01125 S100027_01126 S100027_01126 S100027_01126 1073729 1075318 + Lincomycin resistance protein LmrB Antibiotic resistance%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Proton-dependent transporter. May mediate the efflux of lincomycin. Belongs to the major facilitator superfamily. EmrB family gene gene1125 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01126 S100027_01127 S100027_01127 wrbA wrbA 1075336 1075866 + NAD(P)H dehydrogenase (quinone) Contains 1 flavodoxin-like domain%3B KEGG: bsl:A7A1_3824 NAD(P)H dehydrogenase (quinone) gene gene1126 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01127 S100027_01128 S100027_01128 S100027_01128 1075880 1076212 + hypothetical protein gene gene1127 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01128 S100027_01129 S100027_01129 S100027_01129 1076993 1078144 + Ribose import ATP-binding protein RbsA ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Plasmid%3B Repeat%3B Sugar transport%3B Transport%3B Part of the ABC transporter complex RbsABCD involved in ribose import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Ribose importer (TC 3. A. 1. 2. 1) family%3B Contains 2 ABC transporter domains gene gene1128 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01129 S100027_01130 S100027_01130 S100027_01130 1078137 1079078 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1129 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01130 S100027_01131 S100027_01131 S100027_01131 1079152 1080012 - putative transposase-like protein DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene1130 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01131 S100027_01132 S100027_01132 S100027_01132 1079982 1080314 - hypothetical protein gene gene1131 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01132 S100027_01133 S100027_01133 S100027_01133 1080485 1080685 - Cold shock protein CspB Activator%3B Cytoplasm%3B DNA-binding%3B Stress response%3B Transcription%3B Transcription regulation%3B Binds to the pentamer sequences ATTGG and CCAAT with highest affinity in single-stranded DNA%2C and also to other sequences. Has greater affinity for ATTGG than CCAAT. Can act as transcriptional activator of cold shock genes by recognizing putative ATTGG-box elements present in promoter regions of genes induced under cold shock conditions%3B Contains 1 CSD (cold-shock) domain gene gene1132 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01133 S100027_01134 S100027_01134 S100027_01134 1081202 1082203 + Methionine import ATP-binding protein MetN Amino-acid transport%3B ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Methionine importer (TC 3. A. 1. 24) family%3B Contains 1 ABC transporter domain gene gene1133 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01134 S100027_01135 S100027_01135 S100027_01135 1082206 1082856 + D-methionine transport system permease protein MetI Amino-acid transport%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system for D-methionine and the toxic methionine analog alpha-methyl- methionine. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1134 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01135 S100027_01136 S100027_01136 S100027_01136 1082878 1083696 + D-methionine-binding lipoprotein MetQ Amino-acid transport%3B Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B This protein is a component of a D-methionine permease%2C a binding protein-dependent%2C ATP-driven transport system%3B Belongs to the NlpA lipoprotein family gene gene1135 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01136 S100027_01137 S100027_01137 S100027_01137 1083823 1085208 + L-cystine uptake protein TcyP Amino-acid transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mediates uptake of L-cystine%2C the oxidized form of L- cysteine%3B Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family gene gene1136 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01137 S100027_01138 S100027_01138 S100027_01138 1085254 1085595 - hypothetical protein gene gene1137 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01138 S100027_01139 S100027_01139 preP preP 1085643 1087439 - Prolyl oligopeptidase Aminopeptidase%3B Hydrolase%3B Protease%3B Serine protease%3B Signal%3B Exopeptidase that catalyzes the removal of dipeptide units (NH2-P2-P1- or -P1'-P2'-COOH) from the free amino or carboxy termini. Prefers substrates composed of bulky%2C hydrophobic amino acids at P1 and P1' positions. Has endopeptidase activity on N- terminally blocked peptide derivatives which contain aromatic amino acid residue at the P1 position. Exopeptidase activity is much higher than its endopeptidase activity%3B Belongs to the peptidase S9 family%3B KEGG: cps:CPS_3511 prolyl oligopeptidase gene gene1138 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01139 S100027_01140 S100027_01140 S100027_01140 1087585 1088145 + Lipoprotein YhcN Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Sporulation. gene gene1139 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01140 S100027_01141 S100027_01141 S100027_01141 1088261 1089154 + uncharacterized protein Signal. gene gene1140 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01141 S100027_01142 S100027_01142 S100027_01142 1089148 1089795 - Spore coat protein F-like protein YhcQ Sporulation%3B Belongs to the CotF family gene gene1141 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01142 S100027_01143 S100027_01143 S100027_01143 1090467 1092491 + Protein-glutamate O-methyltransferase Contains 1 cheB-type methylesterase domain%3B Contains 1 cheR-type methyltransferase domain%3B KEGG: bae:BATR1942_02185 two-component system%2C chemotaxis family%2C CheB/CheR fusion protein gene gene1142 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01143 S100027_01144 S100027_01144 S100027_01144 1092604 1096224 + 5'-nucleotidase Calcium%3B Endonuclease%3B Hydrolase%3B Manganese%3B Metal-binding%3B Nuclease%3B Nucleotide-binding%3B Signal%3B Sugar-nonspecific endonuclease that yields nucleotide 3'-monophosphate products. No 5'-nucleotidase activity was detected%2C using 5'-AMP as the substrate%2C in the presence of diverse divalent metals and with various pH values. In the C-terminal sectio%3B belongs to the 5'- nucleotidase family%3B Contains 1 TNase-like domain%3B KEGG: bha:BH1015 5'-nucleotidase gene gene1143 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01144 S100027_01145 S100027_01145 S100027_01145 1096221 1096811 + Sortase A Membrane%3B Transmembrane%3B Transmembrane helix%3B KEGG: bli:BL03172 sortase A gene gene1144 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01145 S100027_01146 S100027_01146 rluD rluD 1096894 1097811 - 23S rRNA pseudouridine(1911/1915/1917) synthase Isomerase%3B RNA-binding%3B Belongs to the pseudouridine synthase RluA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: bli:BL03158 23S rRNA pseudouridine1911/1915/1917 synthase gene gene1145 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01146 S100027_01147 S100027_01147 S100027_01147 1097924 1098292 + uncharacterized protein gene gene1146 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01147 S100027_01148 S100027_01148 S100027_01148 1098461 1098886 + CBS domain-containing protein YhcV CBS domain%3B Repeat%3B Contains 2 CBS domains gene gene1147 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01148 S100027_01149 S100027_01149 S100027_01149 1099025 1099687 + uncharacterized protein Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family gene gene1148 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01149 S100027_01150 S100027_01150 S100027_01150 1099709 1101247 + Hydrolase YhcX Hydrolase%3B Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family%3B Contains 1 CN hydrolase domain%3B Contains 1 N-acetyltransferase domain gene gene1149 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01150 S100027_01151 S100027_01151 S100027_01151 1101343 1101477 + hypothetical protein gene gene1150 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01151 S100027_01152 S100027_01152 S100027_01152 1101583 1103211 + Zinc import ATP-binding protein ZnuC ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Ion transport%3B Membrane%3B Nucleotide-binding%3B Transport%3B Zinc%3B Zinc transport%3B Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Zinc importer (TC 3. A. 1. 15. 5) family%3B Contains 1 ABC transporter domain gene gene1151 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01152 S100027_01153 S100027_01153 S100027_01153 1103460 1104260 + putative transporter YrhG Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the FNT transporter (TC 2. A. 44) family gene gene1152 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01153 S100027_01154 S100027_01154 S100027_01154 1104827 1105738 + putative transporter Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the auxin efflux carrier (TC 2. A. 69) family gene gene1153 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01154 S100027_01155 S100027_01155 S100027_01155 1105845 1106837 - putative zinc-type alcohol dehydrogenase-like protein YogA Oxidoreductase%3B Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily gene gene1154 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01155 S100027_01156 S100027_01156 S100027_01156 1107014 1107571 + Glycerol uptake operon antiterminator regulatory protein Glycerol metabolism%3B RNA-binding%3B Transcription%3B Transcription regulation%3B Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA. May also regulate expression of the glpFK operon gene gene1155 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01156 S100027_01157 S100027_01157 S100027_01157 1107801 1108616 + Glycerol uptake facilitator protein Cell membrane%3B Glycerol metabolism%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Glycerol enters the cell via the glycerol diffusion facilitator protein. This membrane protein facilitates the movement of glycerol across the cytoplasmic membrane. Belongs to the MIP/aquaporin (TC 1. A. 8) family gene gene1156 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01157 S100027_01158 S100027_01158 glpK glpK 1108659 1110149 + Glycerol kinase ATP-binding%3B Glycerol metabolism%3B Kinase%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate%3B Belongs to the FGGY kinase family%3B KEGG: pha:PSHAa0190 glycerol kinase gene gene1157 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01158 S100027_01159 S100027_01159 S100027_01159 1110127 1110321 + hypothetical protein gene gene1158 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01159 S100027_01160 S100027_01160 glpA glpA 1110296 1111963 + Glycerol-3-phosphate dehydrogenase Cytoplasm%3B FAD%3B Flavoprotein%3B Glycerol metabolism%3B Oxidoreductase%3B Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family%3B KEGG: bli:BL02902 glycerol-3-phosphate dehydrogenase gene gene1159 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01160 S100027_01161 S100027_01161 S100027_01161 1112148 1113896 + Phosphoglucomutase (alpha-D-glucose-1%2C6-bisphosphate-dependent) Carbohydrate metabolism%3B Glucose metabolism%3B Isomerase%3B Magnesium%3B Metal-binding%3B Phosphoprotein%3B Catalyzes the interconversion between glucose-6- phosphate and alpha-glucose-1-phosphate. This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG)%2C i. e. the predominant glycolipid found in B. subtilis membrane%2C which is also used as a membrane anchor for lipoteichoic acid (LTA). Has a role in the biosynthesis of all phosphate-containing envelope polymers%2C since glucose-1-phosphate is the precursor of UDP-glucose%2C which serves as a glucosyl donor not only for the biosynthesis of LTA but also for wall teichoic acids (WTAs). Is required for biofilm formation. This is likely due to another role of UDP-glucose%2C which might also act as a metabolic signal regulating biofilm formation or may be involved in some unknown biosynthetic pathway essential for biofilm formation%2C e. g. the synthesis of an exopolysaccharide%3B Belongs to the phosphohexose mutase family%3B KEGG: bli:BL02901 phosphoglucomutase gene gene1160 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01161 S100027_01162 S100027_01162 S100027_01162 1114018 1114476 + uncharacterized protein gene gene1161 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01162 S100027_01163 S100027_01163 S100027_01163 1114498 1114695 + putative HTH-type transcriptional regulator DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene1162 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01163 S100027_01164 S100027_01164 S100027_01164 1114815 1115963 + Histidine kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Two-component regulatory system%3B Member of the two-component regulatory system YhcY/YhcZ. Probably activates YhcZ by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bli:BL02898 two-component system%2C NarL family%2C sensor kinase gene gene1163 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01164 S100027_01165 S100027_01165 S100027_01165 1115951 1116604 + Chemotaxis response regulator protein-glutamate methylesterase Chemotaxis%3B Cytoplasm%3B Hydrolase%3B Phosphoprotein%3B Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene1164 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01165 S100027_01166 S100027_01166 S100027_01166 1116609 1117127 + Azobenzene reductase Flavoprotein%3B FMN%3B NADP%3B Oxidoreductase%3B Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADPH%2C but not NADH%2C as an electron donor for its activity%3B Belongs to the azoreductase type 2 family%3B KEGG: bli:BL02896 azobenzene reductase gene gene1165 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01166 S100027_01167 S100027_01167 S100027_01167 1117157 1117405 - uncharacterized protein gene gene1166 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01167 S100027_01168 S100027_01168 S100027_01168 1117524 1117928 + uncharacterized protein Signal. gene gene1167 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01168 S100027_01169 S100027_01169 S100027_01169 1117959 1118390 - HTH-type transcriptional repressor NsrR 2Fe-2S%3B DNA-binding%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity%3B Contains 1 HTH rrf2-type DNA-binding domain gene gene1168 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01169 S100027_01170 S100027_01170 yhb1 yhb1 1118648 1119862 + Nitric oxide dioxygenase Cytoplasm%3B Detoxification%3B FAD%3B Flavoprotein%3B Heme%3B Iron%3B Metal-binding%3B NAD%3B NADP%3B Oxidoreductase%3B Oxygen transport%3B Transport%3B Is involved in NO detoxification in an aerobic process%2C termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate%2C which protects the cell from various noxious nitrogen compounds. Therefore%2C plays a central role in the inducible response to nitrosative stress%3B In the presence of oxygen and NADH%2C it has NADH oxidase activity%2C which leads to the generation of superoxide and H(2)O(2). Under anaerobic conditions%2C it also exhibits nitric oxide reductase and FAD reductase activities. However%2C all these reactions are much lower than NOD activity (By similarity)%3B Belongs to the globin family. Two-domain flavohemoproteins subfamily%3B In the C-terminal sectio%3B belongs to the flavoprotein pyridine nucleotide cytochrome reductase family%3B Contains 1 FAD-binding FR-type domain%3B KEGG: cps:CPS_0848 nitric oxide dioxygenase gene gene1169 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01170 S100027_01171 S100027_01171 S100027_01171 1120167 1121576 + Stage V sporulation protein Sporulation%3B Appears to be involved in spore cortex formation. To E. coli YcgB gene gene1170 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01171 S100027_01172 S100027_01172 lytE lytE 1121991 1122824 + putative peptidoglycan endopeptidase LytE Cell wall%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Protease%3B Repeat%3B Secreted%3B Signal%3B Thiol protease%3B Cell wall hydrolase that cleaves gamma-D-glutamate-meso- diaminopimelate bonds in peptidoglycan (By similarity). Seems to play a role in cell separation during vegetative growth%3B Belongs to the peptidase C40 family%3B Contains 3 LysM repeats%3B KEGG: bsu:BSU09420 peptidoglycan endopeptidase LytE%3B Acting on peptide bonds (peptidases) gene gene1171 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01172 S100027_01173 S100027_01173 S100027_01173 1122872 1123750 - HTH-type transcriptional regulator CitR Cytoplasm%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Negative regulatory protein for the citA gene for citrate synthase I%3B Contains 1 HTH lysR-type DNA-binding domain gene gene1172 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01173 S100027_01174 S100027_01174 gltA gltA 1123861 1124952 + Citrate (Si)-synthase Allosteric enzyme%3B Transferase%3B Tricarboxylic acid cycle%3B Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect. Belongs to the citrate synthase family%3B KEGG: bli:BL02891 citrate synthase gene gene1173 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01174 S100027_01175 S100027_01175 S100027_01175 1125075 1126139 + Quinoprotein glucose dehydrogenase (PQQ%2C quinone) KEGG: tth:TTC0202 quinoprotein glucose dehydrogenase gene gene1174 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01175 S100027_01176 S100027_01176 S100027_01176 1126218 1127087 + putative oxidoreductase YhdF Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bli:BL02889 null%3B Oxidoreductases gene gene1175 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01176 S100027_01177 S100027_01177 S100027_01177 1127226 1128584 + Sodium-dependent neutral amino acid transporter B(0)AT2 Amino-acid transport%3B Glycoprotein%3B Ion transport%3B Membrane%3B Neurotransmitter transport%3B Phosphoprotein%3B Sodium%3B Sodium transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Functions as a sodium-dependent neutral amino acid transporter. Exhibits preference for methionine and for the branched-chain amino acids%2C particularly leucine%2C valine and isoleucine. Mediates the saturable%2C pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1:1. May have a role as transporter for neurotransmitter precursors into neurons. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2. A. 22) family. SLC6A15 subfamily gene gene1176 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01177 S100027_01178 S100027_01178 gadB gadB 1128606 1130234 + Glutamate decarboxylase Decarboxylase%3B Lyase%3B Neurotransmitter biosynthesis%3B Phosphoprotein%3B Pyridoxal phosphate%3B Catalyzes the production of GABA%3B Belongs to the group II decarboxylase family%3B KEGG: olu:OSTLU_36228 glutamate decarboxylase gene gene1177 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01178 S100027_01179 S100027_01179 S100027_01179 1130272 1131159 - putative HTH-type transcriptional regulator YdeE Cytoplasm%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH araC/xylS-type DNA-binding domain gene gene1178 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01179 S100027_01180 S100027_01180 S100027_01180 1131237 1132649 - putative HTH-type transcriptional regulator YdeL Aminotransferase%3B DNA-binding%3B Pyridoxal phosphate%3B Transcription%3B Transcription regulation%3B Transferase%3B In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene1179 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01180 S100027_01181 S100027_01181 S100027_01181 1132762 1133196 + putative N-acetyltransferase YhdJ Acyltransferase%3B Transferase%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: reh:H16_B1407 null%3B Transferring groups other than amino-acyl groups gene gene1180 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01181 S100027_01182 S100027_01182 S100027_01182 1133225 1133515 - putative anti-sigma-M factor YhdK Cell membrane%3B Membrane%3B Repressor%3B Transcription%3B Transcription regulation%3B Transmembrane%3B Transmembrane helix. gene gene1181 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01182 S100027_01183 S100027_01183 S100027_01183 1133503 1134573 - putative anti-sigma-M factor YhdL Membrane%3B Repressor%3B Transcription%3B Transcription regulation%3B Transmembrane%3B Transmembrane helix. gene gene1182 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01183 S100027_01184 S100027_01184 S100027_01184 1134566 1135057 - RNA polymerase sigma factor SigM DNA-binding%3B Sigma factor%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor may be involved in the maintenance of membrane and cell wall integrity in response to salt%2C acid and ethanol stress. Belongs to the sigma-70 factor family. ECF subfamily gene gene1183 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01184 S100027_01185 S100027_01185 S100027_01185 1135347 1135889 - uncharacterized protein ATP-binding%3B Nucleotide-binding. gene gene1184 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01185 S100027_01186 S100027_01186 S100027_01186 1136010 1136282 + hypothetical protein gene gene1185 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01186 S100027_01187 S100027_01187 plsC plsC 1136348 1136947 + 1-acylglycerol-3-phosphate O-acyltransferase Acyltransferase%3B Cell membrane%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) by incorporating an acyl moiety at the 2 position. This enzyme utilizes acyl-ACP as fatty acyl donor%2C but not acyl-CoA%3B Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family%3B KEGG: blh:BaLi_c11330 1-acyl-sn-glycerol-3-phosphate acyltransferase gene gene1186 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01187 S100027_01188 S100027_01188 S100027_01188 1136904 1137047 + hypothetical protein gene gene1187 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01188 S100027_01189 S100027_01189 S100027_01189 1137109 1137474 + Inner membrane protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B To E. coli YhaH gene gene1188 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01189 S100027_01190 S100027_01190 S100027_01190 1137505 1138782 - Bile acid-CoA:amino acid N-acyltransferase Acyltransferase%3B Fatty acid metabolism%3B Hydrolase%3B Lipid metabolism%3B Peroxisome%3B Phosphoprotein%3B Serine esterase%3B Transferase%3B Involved in bile acid metabolism. In liver hepatocytes catalyzes the second step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi. The major components of bile are cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl-CoA thioester%2C either in peroxisomes (primary bile acids deriving from the cholesterol pathway)%2C or cytoplasmic at the endoplasmic reticulum (secondary bile acids). May catalyze the conjugation of primary or secondary bile acids%2C or both. The conjugation increases the detergent properties of bile acids in the intestine%2C which facilitates lipid and fat-soluble vitamin absorption. In turn%2C bile acids are deconjugated by bacteria in the intestine and are recycled back to the liver for reconjugation (secondary bile acids). May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro%2C catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH)%2C and conjugates glycine to these acyl-CoAs (By similarity)%3B Belongs to the C/M/P thioester hydrolase family gene gene1189 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01190 S100027_01191 S100027_01191 S100027_01191 1138779 1139375 - putative HTH-type transcriptional regulator YvkB DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH tetR-type DNA-binding domain gene gene1190 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01191 S100027_01192 S100027_01192 S100027_01192 1139506 1140825 - UPF0053 protein YhdP CBS domain%3B Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0053 family%3B Contains 2 CBS domains%3B Contains 1 DUF21 domain gene gene1191 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01192 S100027_01193 S100027_01193 S100027_01193 1140886 1141311 - HTH-type transcriptional regulator CueR Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Transcriptional activator of the copZA operon%3B Contains 1 HTH merR-type DNA-binding domain gene gene1192 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01193 S100027_01194 S100027_01194 S100027_01194 1141415 1141585 - hypothetical protein gene gene1193 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01194 S100027_01195 S100027_01195 S100027_01195 1141626 1142999 + UPF0053 protein YhdT CBS domain%3B Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0053 family%3B Contains 2 CBS domains%3B Contains 1 DUF21 domain gene gene1194 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01195 S100027_01196 S100027_01196 S100027_01196 1143097 1143498 + hypothetical protein gene gene1195 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01196 S100027_01197 S100027_01197 S100027_01197 1143707 1143994 + hypothetical protein gene gene1196 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01197 S100027_01198 S100027_01198 S100027_01198 1143957 1144634 + N-acetylmuramoyl-L-alanine amidase Cell wall%3B Cell wall biogenesis/degradation%3B Competence%3B Hydrolase%3B Metal-binding%3B Repeat%3B Secreted%3B Sporulation%3B Zinc%3B Autolysins are involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella - in particular of its basal body - and sporulation. CwlC is able to hydrolyze type A cell walls such as B. subtilis. Its main function is to lyze the mother cell wall peptidoglycan%2C playing a role during sporulation%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B Contains 1 SPOR domain%3B KEGG: bsu:BSU17410 N-acetylmuramoyl-L-alanine amidase gene gene1197 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01198 S100027_01199 S100027_01199 S100027_01199 1144804 1145160 - Putative fluoride ion transporter CrcB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Important for reducing fluoride concentration in the cell%2C thus reducing its toxicity%3B Belongs to the CrcB (TC 9. B. 71) family%3B overlaps another CDS with the same product name gene gene1198 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01199 S100027_01200 S100027_01200 S100027_01200 1145157 1145555 - Putative fluoride ion transporter CrcB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Important for reducing fluoride concentration in the cell%2C thus reducing its toxicity%3B Belongs to the CrcB (TC 9. B. 71) family%3B overlaps another CDS with the same product name gene gene1199 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01200 S100027_01201 S100027_01201 glpQ glpQ 1145571 1146275 - Glycerophosphodiester phosphodiesterase Calcium%3B Glycerol metabolism%3B Hydrolase%3B Metal-binding%3B Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to sn-glycerol 3-phosphate (G3P) and the corresponding alcohols%3B Belongs to the glycerophosphoryl diester phosphodiesterase family%3B Contains 1 GP-PDE domain%3B KEGG: fau:Fraau_3181 glycerophosphoryl diester phosphodiesterase gene gene1200 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01201 S100027_01202 S100027_01202 S100027_01202 1146467 1146574 + uncharacterized protein gene gene1201 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01202 S100027_01203 S100027_01203 S100027_01203 1146758 1147834 + putative MscS family protein YhdY Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B May play a role in resistance to osmotic downshock%3B Belongs to the MscS (TC 1. A. 23) family gene gene1202 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01203 S100027_01204 S100027_01204 npdA npdA 1147863 1148612 + NAD-dependent protein deacetylase Cytoplasm%3B Hydrolase%3B Metal-binding%3B NAD%3B Zinc%3B NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form%3B Belongs to the sirtuin family. Class U subfamily%3B Contains 1 deacetylase sirtuin-type domain%3B KEGG: bli:BL02876 NAD-dependent deacetylase%3B In linear amides gene gene1203 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01204 S100027_01205 S100027_01205 S100027_01205 1148733 1150163 + hypothetical protein gene gene1204 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01205 S100027_01206 S100027_01206 S100027_01206 1150199 1150693 - hypothetical protein gene gene1205 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01206 S100027_01207 S100027_01207 S100027_01207 1150828 1151739 - Chitin deacetylase Cell membrane%3B Hydrolase%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the polysaccharide deacetylase family%3B KEGG: bcz:BCZK1658 chitin deacetylase gene gene1206 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01207 S100027_01208 S100027_01208 S100027_01208 1152037 1152888 + D-amino-acid transaminase Aminotransferase%3B Pyridoxal phosphate%3B Transferase%3B Acts on the D-isomers of alanine%2C leucine%2C aspartate%2C glutamate%2C aminobutyrate%2C norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction. The second half-reaction is the reverse of the first%2C transferring the amino group from the pyridoxamine to a second alpha-keto acid to form the product D- amino acid via a ping-pong mechanism. This is an important process in the formation of D-alanine and D-glutamate%2C which are essential bacterial cell wall components (By similarity)%3B Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bli:BL02875 D-alanine transaminase gene gene1207 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01208 S100027_01209 S100027_01209 S100027_01209 1152927 1154285 - Na(+)/H(+) antiporter NhaC Antiport%3B Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Na(+)/H(+) antiporter. Involved in pH homeostasis and sodium extrusion%3B Belongs to the NhaC Na(+)/H(+) (TC 2. A. 35) antiporter family gene gene1208 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01209 S100027_01210 S100027_01210 galM galM 1154521 1155501 + Aldose 1-epimerase Carbohydrate metabolism%3B Isomerase%3B Belongs to the aldose epimerase family%3B KEGG: bli:BL02874 aldose 1-epimerase gene gene1209 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01210 S100027_01211 S100027_01211 S100027_01211 1155517 1155993 - uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1210 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01211 S100027_01212 S100027_01212 S100027_01212 1156067 1158001 - hypothetical protein gene gene1211 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01212 S100027_01213 S100027_01213 S100027_01213 1158001 1159854 - hypothetical protein gene gene1212 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01213 S100027_01214 S100027_01214 S100027_01214 1161063 1161563 - Stress response protein NhaX Stress response%3B Belongs to the universal stress protein A family gene gene1213 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01214 S100027_01215 S100027_01215 S100027_01215 1162084 1163838 + putative multidrug resistance ABC transporter ATP-binding/permease protein YheI Antibiotic resistance%3B ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the transport of four structurally unrelated drugs%2C including doxorubicin and mitoxantrone. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene1214 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01215 S100027_01216 S100027_01216 S100027_01216 1163835 1165853 + putative multidrug resistance ABC transporter ATP-binding/permease protein YheH Antibiotic resistance%3B ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the transport of four structurally unrelated drugs%2C including doxorubicin and mitoxantrone. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene1215 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01216 S100027_01217 S100027_01217 S100027_01217 1165873 1166520 - uncharacterized protein gene gene1216 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01217 S100027_01218 S100027_01218 S100027_01218 1166517 1166660 - hypothetical protein gene gene1217 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01218 S100027_01219 S100027_01219 S100027_01219 1166831 1167034 - Small%2C acid-soluble spore protein DNA-binding%3B Sporulation%3B SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. Belongs to the alpha/beta-type SASP family gene gene1218 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01219 S100027_01220 S100027_01220 S100027_01220 1167270 1167494 + hypothetical protein gene gene1219 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01220 S100027_01221 S100027_01221 S100027_01221 1167540 1168646 - Phosphonates import ATP-binding protein PhnC ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Phosphonate transport%3B Transport%3B Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3. A. 1. 9. 1) family%3B Contains 1 ABC transporter domain gene gene1220 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01221 S100027_01222 S100027_01222 S100027_01222 1168762 1169643 - uncharacterized protein Coiled coil. gene gene1221 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01222 S100027_01223 S100027_01223 S100027_01223 1169662 1169871 - uncharacterized protein gene gene1222 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01223 S100027_01224 S100027_01224 S100027_01224 1170024 1171382 - Endospore coat-associated protein YheD Membrane%3B Sporulation%3B Involved in sporulation%3B Belongs to the YheC/YheD family gene gene1223 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01224 S100027_01225 S100027_01225 S100027_01225 1171379 1172464 - Endospore coat-associated protein YheC Membrane%3B Sporulation%3B Involved in sporulation%3B Belongs to the YheC/YheD family gene gene1224 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01225 S100027_01226 S100027_01226 S100027_01226 1172794 1173924 + UPF0754 membrane protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0754 family gene gene1225 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01226 S100027_01227 S100027_01227 S100027_01227 1174047 1174400 + UPF0342 protein Belongs to the UPF0342 family gene gene1226 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01227 S100027_01228 S100027_01228 S100027_01228 1174847 1175710 + Stress response protein YhaX Stress response. gene gene1227 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01228 S100027_01229 S100027_01229 hemN hemN 1175739 1177358 + Coproporphyrinogen dehydrogenase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase%3B Porphyrin biosynthesis%3B S-adenosyl-L-methionine%3B Involved in the biosynthesis of porphyrin-containing compound%3B Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemZ subfamily%3B KEGG: bli:BL02869 oxygen-independent coproporphyrinogen III oxidase gene gene1228 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01229 S100027_01230 S100027_01230 S100027_01230 1177440 1178651 - K(+)/H(+) antiporter YhaU Antiport%3B Cell membrane%3B Ion transport%3B Membrane%3B Potassium%3B Potassium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Potassium/proton antiporter that mediates the efflux of potassium ions from the cell. Potassium antiport activity requires the presence of KhtT. Has higher activity at alkaline pH. Can also mediate rubidium/proton antiport. Has no permeability for sodium or lithium ions%3B Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2. A. 37) family gene gene1229 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01230 S100027_01231 S100027_01231 S100027_01231 1178658 1179155 - K(+)/H(+) antiporter subunit KhtT Cell membrane%3B Membrane%3B Modulates the activity of the potassium/proton antiporter YhaU. The transporter is composed of the integral membrane protein YhaU and the regulatory protein KhtT%3B Contains 1 RCK C-terminal domain gene gene1230 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01231 S100027_01232 S100027_01232 S100027_01232 1179220 1179549 - hypothetical protein gene gene1231 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01232 S100027_01233 S100027_01233 liuC liuC 1179750 1180526 + Methylglutaconyl-CoA hydratase Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the enoyl-CoA hydratase/isomerase family%3B KEGG: mro:MROS_2743 methylglutaconyl-CoA hydratase gene gene1232 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01233 S100027_01234 S100027_01234 rapJ rapJ 1180881 1181615 + Response regulator aspartate phosphatase Hydrolase%3B Protein phosphatase%3B Repeat%3B Sporulation%3B TPR repeat%3B Prevents sporulation by dephosphorylating Spo0F%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bsu:BSU02820 response regulator aspartate phosphatase J%3B Acting on ester bonds gene gene1233 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01234 S100027_01235 S100027_01235 S100027_01235 1181721 1181858 + hypothetical protein gene gene1234 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01235 S100027_01236 S100027_01236 S100027_01236 1181863 1182141 + hypothetical protein gene gene1235 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01236 S100027_01237 S100027_01237 S100027_01237 1182214 1182399 - uncharacterized protein gene gene1236 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01237 S100027_01238 S100027_01238 rbsA rbsA 1182517 1183413 + Monosaccharide-transporting ATPase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Phosphonate transport%3B Plasmid%3B Transport%3B Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3. A. 1. 9. 1) family%3B Contains 1 ABC transporter domain%3B KEGG: sod:Sant_0208 ribose transport system ATP-binding protein gene gene1237 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01238 S100027_01239 S100027_01239 S100027_01239 1183406 1184674 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B To M. jannaschii MJ1024 gene gene1238 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01239 S100027_01240 S100027_01240 S100027_01240 1184794 1186020 + putative metallophosphoesterase YhaO Hydrolase%3B Metal-binding%3B Belongs to the metallophosphoesterase superfamily gene gene1239 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01240 S100027_01241 S100027_01241 S100027_01241 1186034 1189000 + uncharacterized protein Cell membrane%3B Coiled coil%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1240 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01241 S100027_01242 S100027_01242 cbf1 cbf1 1189050 1189994 + 3'-5' exoribonuclease YhaM DNA-binding%3B Exonuclease%3B Hydrolase%3B Nuclease%3B Shows a 3'-5' exoribonuclease activity%3B Belongs to the YhaM family%3B Contains 1 HD domain%3B Contains 1 OB DNA-binding domain%3B KEGG: bsu:BSU09930 3'-5' exoribonuclease%3B Acting on ester bonds gene gene1241 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01242 S100027_01243 S100027_01243 S100027_01243 1190063 1190296 + Sporulation protein YhaL Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Required for efficient sporulation gene gene1242 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01243 S100027_01244 S100027_01244 S100027_01244 1190342 1191202 - Peptidylprolyl isomerase Cell membrane%3B Isomerase%3B Lipoprotein%3B Membrane%3B Palmitate%3B Rotamase%3B Signal%3B Essential protein that plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins. Has PPIase activity but it is not essential for its function in vivo%3B Belongs to the PrsA family%3B Contains 1 PpiC domain%3B KEGG: bsu:BSU09950 foldase protein PrsA gene gene1243 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01244 S100027_01245 S100027_01245 S100027_01245 1191580 1191678 + hypothetical protein gene gene1244 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01245 S100027_01246 S100027_01246 S100027_01246 1192025 1192540 - putative membrane protein YhaJ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1245 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01246 S100027_01247 S100027_01247 S100027_01247 1192754 1193101 + uncharacterized protein gene gene1246 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01247 S100027_01248 S100027_01248 S100027_01248 1193098 1193718 - HTH-type transcriptional regulator Hpr DNA-binding%3B Repressor%3B Sporulation%3B Transcription%3B Transcription regulation%3B Negative regulator of protease production and sporulation%3B Contains 1 HTH marR-type DNA-binding domain gene gene1247 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01248 S100027_01249 S100027_01249 S100027_01249 1193912 1194268 - putative membrane protein YhaH Cell membrane%3B Coiled coil%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1248 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01249 S100027_01250 S100027_01250 S100027_01250 1194430 1194621 + putative membrane protein YhzF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1249 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01250 S100027_01251 S100027_01251 S100027_01251 1194712 1195239 - putative tryptophan transport protein Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably involved in tryptophan uptake. Belongs to the TrpP transporter family gene gene1250 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01251 S100027_01252 S100027_01252 serC serC 1195382 1196503 - Phosphoserine transaminase Amino-acid biosynthesis%3B Aminotransferase%3B Cytoplasm%3B Pyridoxal phosphate%3B Serine biosynthesis%3B Transferase%3B Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily%3B KEGG: bsu:BSU10020 phosphoserine aminotransferase gene gene1251 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01252 S100027_01253 S100027_01253 S100027_01253 1196654 1197073 - Protein HitA Contains 1 HIT domain gene gene1252 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01253 S100027_01254 S100027_01254 S100027_01254 1197601 1198341 + Polar-amino-acid-transporting ATPase ATP-binding%3B Competence%3B Nucleotide-binding%3B Sporulation%3B Transport%3B Has a role in exoprotein production%2C sporulation and competence. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: cama:F384_08655 polar amino acid transport system ATP-binding protein gene gene1253 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01254 S100027_01255 S100027_01255 S100027_01255 1198334 1199560 + Protein EcsB Cell membrane%3B Competence%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Presumed to form part of an ABC-transporter%2C it may form a transport channel gene gene1254 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01255 S100027_01256 S100027_01256 S100027_01256 1199609 1200319 + Protein EcsC gene gene1255 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01256 S100027_01257 S100027_01257 S100027_01257 1200350 1201570 - Putative amidohydrolase YhaA Cobalt%3B Hydrolase%3B Metal-binding%3B Zinc%3B Belongs to the peptidase M20A family%3B KEGG: tep:TepRe1_0059 amidohydrolase%3B In linear amides gene gene1256 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01257 S100027_01258 S100027_01258 S100027_01258 1201652 1203025 - putative membrane protein YhfA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1257 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01258 S100027_01259 S100027_01259 S100027_01259 1203134 1203637 - Heme-degrading monooxygenase HmoB Cytoplasm%3B Heme%3B Iron%3B Metal-binding%3B Monooxygenase%3B Oxidoreductase%3B Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase%2C with subsequent release of free iron%3B Belongs to the antibiotic biosynthesis monooxygenase family%3B Contains 1 ABM domain gene gene1258 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01259 S100027_01260 S100027_01260 S100027_01260 1203770 1205908 + Penicillin-binding protein 1F Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Peptidoglycan synthesis%3B Signal-anchor%3B Transmembrane%3B Transmembrane helix%3B Cell wall formation. May be involved in outgrowth of the germinated spore or it could function in the synthesis of the germ cell wall. In the N-terminal sectio%3B belongs to the glycosyltransferase 51 family%3B In the C-terminal sectio%3B belongs to the transpeptidase family%3B KEGG: bli:BL01071 penicillin-binding protein 2A%3B Peptidoglycan glycosyltransferase gene gene1259 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01260 S100027_01261 S100027_01261 hemE hemE 1206034 1207095 + Uroporphyrinogen decarboxylase Cytoplasm%3B Decarboxylase%3B Lyase%3B Porphyrin biosynthesis%3B Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III%3B Belongs to the uroporphyrinogen decarboxylase family%3B KEGG: bli:BL01072 uroporphyrinogen decarboxylase gene gene1260 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01261 S100027_01262 S100027_01262 hemH hemH 1207169 1208107 + Protoporphyrin ferrochelatase Cytoplasm%3B Heme biosynthesis%3B Iron%3B Lyase%3B Metal-binding%3B Porphyrin biosynthesis%3B Catalyzes the ferrous insertion into protoporphyrin IX%3B Belongs to the ferrochelatase family%3B KEGG: bsu:BSU10130 ferrochelatase gene gene1261 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01262 S100027_01263 S100027_01263 ppoX ppoX 1208123 1209535 + Protoporphyrinogen oxidase Cytoplasm%3B FAD%3B Flavoprotein%3B Oxidoreductase%3B Porphyrin biosynthesis%3B Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. Also oxidizes the pathway intermediate coproporphyrinogen-III%3B Belongs to the protoporphyrinogen oxidase family%3B KEGG: bli:BL01074 oxygen-dependent protoporphyrinogen oxidase gene gene1262 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01263 S100027_01264 S100027_01264 S100027_01264 1209732 1210304 + putative HTH-type transcriptional regulator YhgD DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH tetR-type DNA-binding domain gene gene1263 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01264 S100027_01265 S100027_01265 S100027_01265 1210378 1212540 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B To L. lactis phage infection protein (PIP) gene gene1264 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01265 S100027_01266 S100027_01266 fabH fabH 1212596 1213591 - Beta-ketoacyl-[acyl-carrier-protein] synthase III Acyltransferase%3B Cytoplasm%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Multifunctional enzyme%3B Transferase%3B Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and/or straight-chain of fatty acids%3B Belongs to the FabH family%3B KEGG: bli:BL01107 3-oxoacyl-(acyl-carrier-protein) synthase III gene gene1265 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01266 S100027_01267 S100027_01267 S100027_01267 1213698 1214735 + Cellulase Aminopeptidase%3B Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Belongs to the peptidase M42 family%3B KEGG: tpe:Tpen_0002 endoglucanase gene gene1266 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01267 S100027_01268 S100027_01268 S100027_01268 1214814 1215011 - hypothetical protein gene gene1267 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01268 S100027_01269 S100027_01269 S100027_01269 1215173 1216459 - Proton/sodium-glutamate symport protein Cell membrane%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B This carrier protein is part of the Na(+)-dependent%2C binding-protein-independent glutamate-aspartate transport system%3B Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family gene gene1268 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01269 S100027_01270 S100027_01270 S100027_01270 1216767 1216901 - uncharacterized protein gene gene1269 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01270 S100027_01271 S100027_01271 S100027_01271 1217058 1217792 + putative metallo-hydrolase YhfI Hydrolase%3B Metal-binding%3B Zinc%3B Belongs to the metallo-beta-lactamase superfamily gene gene1270 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01271 S100027_01272 S100027_01272 lplA lplA 1217811 1218800 + Lipoate--protein ligase ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Transferase%3B Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. Is also able to use octanoate as substrate%3B Belongs to the LplA family%3B Contains 1 BPL/LPL catalytic domain%3B KEGG: bsu:BSU10250 lipoate-protein ligase A gene gene1271 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01272 S100027_01273 S100027_01273 S100027_01273 1218963 1220504 + Long-chain-fatty-acid--CoA ligase ATP-binding%3B Fatty acid metabolism%3B Ligase%3B Lipid degradation%3B Lipid metabolism%3B Nucleotide-binding%3B Involved in the degradation of long-chain fatty acids. Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bli:BL01080 long-chain acyl-CoA synthetase gene gene1272 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01273 S100027_01274 S100027_01274 S100027_01274 1220475 1220942 - hypothetical protein gene gene1273 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01274 S100027_01275 S100027_01275 S100027_01275 1221049 1221600 + HTH-type transcriptional regulator SutR Activator%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Regulates the expression of 12-16 transcription units involved in various steps of sulfur utilization. Represses expression of pfkB%2C fliZ%2C cysE%2C ydcO and its own expression. Activates expression of ypfN. Acts by binding to SutR boxes%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene1274 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01275 S100027_01276 S100027_01276 S100027_01276 1221613 1222329 + putative membrane protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the AzlC family gene gene1275 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01276 S100027_01277 S100027_01277 S100027_01277 1222322 1222633 + hypothetical protein gene gene1276 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01277 S100027_01278 S100027_01278 S100027_01278 1222705 1223961 + Ste24 endopeptidase Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Zinc%3B Belongs to the peptidase M48B family%3B KEGG: tte:TTE0991 STE24 endopeptidase gene gene1277 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01278 S100027_01279 S100027_01279 aprE aprE 1224019 1225158 - Subtilisin Calcium%3B Hydrolase%3B Metal-binding%3B Protease%3B Secreted%3B Serine protease%3B Signal%3B Sporulation%3B Zymogen%3B Subtilisin is an extracellular alkaline serine protease%2C it catalyzes the hydrolysis of proteins and peptide amides. Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bli:BL01111 subtilisin gene gene1278 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01279 S100027_01280 S100027_01280 S100027_01280 1225569 1226468 + putative transporter YdeD Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene1279 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01280 S100027_01281 S100027_01281 S100027_01281 1226576 1227553 + Putative ABC transporter substrate-binding lipoprotein YhfQ Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene1280 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01281 S100027_01282 S100027_01282 S100027_01282 1227636 1228634 + Iron(3+)-hydroxamate import system permease protein FhuG Cell membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex FhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene1281 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01282 S100027_01283 S100027_01283 S100027_01283 1228634 1229662 + Fe(3+)-citrate import system permease protein YfmD Cell membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex YfmCDEF involved in citrate-dependent Fe(3+) import. Involved in the translocation of the substrate across the membrane (Probable)%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene1282 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01283 S100027_01284 S100027_01284 S100027_01284 1229675 1230247 - putative phosphatase PhoE Hydrolase%3B Phosphatase with broad substrate specificity. Does not have phosphoglycerate mutase activity%3B Belongs to the phosphoglycerate mutase family. GpmB subfamily gene gene1283 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01284 S100027_01285 S100027_01285 S100027_01285 1230532 1231824 - Heme-based aerotactic transducer HemAT Heme%3B Iron%3B Metal-binding%3B Transducer%3B Heme-containing signal transducer responsible for aerotaxis%2C the migratory response toward or away from oxygen%3B Contains 1 methyl-accepting transducer domain gene gene1284 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01285 S100027_01286 S100027_01286 S100027_01286 1231931 1233460 - Putative Rieske 2Fe-2S iron-sulfur protein YhfW 2Fe-2S%3B Disulfide bond%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase%3B Contains 1 Rieske domain%3B KEGG: ctc:CTC00417 null%3B With NAD(+) or NADP(+) as acceptor gene gene1285 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01286 S100027_01287 S100027_01287 S100027_01287 1233601 1234458 + putative oxidoreductase YhxC Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bld:BLi01117 null%3B Oxidoreductases gene gene1286 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01287 S100027_01288 S100027_01288 S100027_01288 1234524 1234757 - uncharacterized protein gene gene1287 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01288 S100027_01289 S100027_01289 S100027_01289 1235030 1235608 + Competence transcription factor Activator%3B Competence%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Intermediate regulatory gene required for the expression of the late competence genes comC%2C comE%2C comG and the bdbDC operon. Receives signals from SrfA%2C and possibly other regulatory COM genes%2C and transduces these signals to the late COM genes gene gene1288 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01289 S100027_01290 S100027_01290 S100027_01290 1235602 1235967 - uncharacterized protein Coiled coil. gene gene1289 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01290 S100027_01291 S100027_01291 S100027_01291 1236176 1236787 + putative membrane protein YhjE Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1290 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01291 S100027_01292 S100027_01292 S100027_01292 1236800 1237318 + Signal peptidase I Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Belongs to the peptidase S26 family%3B KEGG: bli:BL01092 signal peptidase I gene gene1291 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01292 S100027_01293 S100027_01293 S100027_01293 1237473 1239248 - Minor extracellular protease Epr Hydrolase%3B Protease%3B Secreted%3B Serine protease%3B Signal%3B Zymogen%3B Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bli:BL01118 minor extracellular protease Epr%3B Serine endopeptidases gene gene1292 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01293 S100027_01294 S100027_01294 S100027_01294 1239623 1240864 + putative sulfoacetate transporter SauU Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B May transport sulfoacetate into the cell%3B Belongs to the major facilitator superfamily gene gene1293 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01294 S100027_01295 S100027_01295 S100027_01295 1240893 1242506 - Purine catabolism regulatory protein Activator%3B DNA-binding%3B Purine metabolism%3B Repressor%3B Transcription%3B Transcription regulation%3B Activates the expression of pucFG%2C pucH%2C pucI%2C pucJKLM and guaD%2C while it represses pucABCDE and its own expression%3B Belongs to the CdaR family gene gene1294 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01295 S100027_01296 S100027_01296 S100027_01296 1242660 1242749 + hypothetical protein gene gene1295 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01296 S100027_01297 S100027_01297 dpyS dpyS 1243335 1244699 + Dihydropyrimidinase Hydrolase%3B Metal-binding%3B Purine metabolism%3B Zinc%3B Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring%3B Belongs to the DHOase family. Allantoinase subfamily%3B KEGG: mey:TM49_03535 dihydropyrimidinase gene gene1296 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01297 S100027_01298 S100027_01298 allC allC 1245367 1246554 + Allantoate deiminase Hydrolase%3B Metal-binding%3B Purine metabolism%3B Zinc%3B Involved in the anaerobic utilization of allantoin. Converts allantoate to (S)-ureidoglycolate and ammonia%3B Belongs to the peptidase M20 family%3B KEGG: bli:BL01095 allantoate deiminase gene gene1297 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01298 S100027_01299 S100027_01299 ylbA ylbA 1246578 1247366 + (S)-ureidoglycine aminohydrolase Cytoplasm%3B Hydrolase%3B Manganese%3B Metal-binding%3B Purine metabolism%3B Involved in the catabolism of purine nucleotides. Catalyzes the second%2C stereospecific hydrolysis reaction of the allantoin degradation pathway%2C producing S-ureidoglycolate and ammonia from S-ureidoglycine%3B Belongs to the UGHY family%3B KEGG: bli:BL01096 (S)-ureidoglycine aminohydrolase gene gene1298 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01299 S100027_01300 S100027_01300 allD allD 1247382 1248410 + Ureidoglycolate dehydrogenase (NAD(+)) Cytoplasm%3B NAD%3B Oxidoreductase%3B Purine metabolism%3B Involved in the anaerobic utilization of allantoin. Belongs to the LDH2/MDH2 oxidoreductase family%3B KEGG: bli:BL01097 ureidoglycolate dehydrogenase (NAD+) gene gene1299 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01300 S100027_01301 S100027_01301 S100027_01301 1248434 1249222 + Ureidoglycolate dehydrogenase (NAD(+)) Cytoplasm%3B NAD%3B Oxidoreductase%3B Purine metabolism%3B Involved in the anaerobic utilization of allantoin. Belongs to the LDH2/MDH2 oxidoreductase family%3B KEGG: yin:CH53_61 ureidoglycolate dehydrogenase (NAD+) gene gene1300 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01301 S100027_01302 S100027_01302 S100027_01302 1249232 1249483 + Ureidoglycolate dehydrogenase (NAD(+)) Cytoplasm%3B NAD%3B Oxidoreductase%3B Purine metabolism%3B Involved in the anaerobic utilization of allantoin. Belongs to the LDH2/MDH2 oxidoreductase family%3B KEGG: sty:STY0576 ureidoglycolate dehydrogenase (NAD+) gene gene1301 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01302 S100027_01303 S100027_01303 S100027_01303 1249501 1251258 + uncharacterized protein To E. coli FdrA and some%2C to bacterial SucD%3B overlaps another CDS with the same product name gene gene1302 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01303 S100027_01304 S100027_01304 S100027_01304 1251258 1252523 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B To E. coli YlbE%3B overlaps another CDS with the same product name gene gene1303 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01304 S100027_01305 S100027_01305 S100027_01305 1252520 1253290 + hypothetical protein gene gene1304 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01305 S100027_01306 S100027_01306 arcC arcC 1253296 1254228 + Carbamate kinase Arginine metabolism%3B ATP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the carbamate kinase family%3B KEGG: bli:BL01102 carbamate kinase gene gene1305 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01306 S100027_01307 S100027_01307 S100027_01307 1254444 1255697 + putative sugar efflux transporter Cell inner membrane%3B Cell membrane%3B Membrane%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites%3B Belongs to the major facilitator superfamily. SotB (TC 2. A. 1. 2) family gene gene1306 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01307 S100027_01308 S100027_01308 S100027_01308 1255725 1256063 + uncharacterized protein Signal. gene gene1307 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01308 S100027_01309 S100027_01309 rapG rapG 1256366 1257466 + Response regulator aspartate phosphatase Hydrolase%3B Protein phosphatase%3B Repeat%3B TPR repeat%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bli:BL01363 response regulator aspartate phosphatase G%3B Acting on ester bonds gene gene1308 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01309 S100027_01310 S100027_01310 S100027_01310 1257466 1257582 + hypothetical protein gene gene1309 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01310 S100027_01311 S100027_01311 S100027_01311 1258438 1258965 - hypothetical protein gene gene1310 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01311 S100027_01312 S100027_01312 S100027_01312 1259071 1259565 + hypothetical protein gene gene1311 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01312 S100027_01313 S100027_01313 S100027_01313 1259823 1260860 + HTH-type transcriptional regulator EbgR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Repressor for beta galactosidase alpha and beta subunits (ebgA and ebgC). Binds lactose as an inducer. Contains 1 HTH lacI-type DNA-binding domain gene gene1312 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01313 S100027_01314 S100027_01314 S100027_01314 1260974 1262227 + Putative binding protein MsmE Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B Probably part of an ABC transporter complex. Belongs to the bacterial solute-binding protein 1 family gene gene1313 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01314 S100027_01315 S100027_01315 S100027_01315 1262267 1263187 + Putative ABC transporter permease protein AmyD Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably part of an ABC transporter complex. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene1314 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01315 S100027_01316 S100027_01316 S100027_01316 1263188 1264018 + Putative ABC transporter permease protein AmyC Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably part of an ABC transporter complex. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene1315 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01316 S100027_01317 S100027_01317 melA melA 1264049 1265347 + Alpha-galactosidase Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Manganese%3B Metal-binding%3B NAD%3B Belongs to the glycosyl hydrolase 4 family%3B KEGG: dsh:Dshi_1245 alpha-galactosidase gene gene1316 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01317 S100027_01318 S100027_01318 S100027_01318 1265372 1266526 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the AbrB family gene gene1317 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01318 S100027_01319 S100027_01319 S100027_01319 1266737 1266970 + Protein CotJA gene gene1318 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01319 S100027_01320 S100027_01320 S100027_01320 1266976 1267239 + Protein CotJB gene gene1319 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01320 S100027_01321 S100027_01321 S100027_01321 1267261 1267830 + Protein CotJC The cotJ operon proteins affect spore coat composition. They are either required for the normal formation of the inner layers of the coat or are themselves structural components of the coat. Belongs to the manganese catalase family gene gene1320 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01321 S100027_01322 S100027_01322 S100027_01322 1267874 1269493 - Long-chain-fatty-acid--CoA ligase ATP-binding%3B Cholesterol metabolism%3B Ligase%3B Lipid metabolism%3B Nucleotide-binding%3B Steroid metabolism%3B Sterol metabolism%3B Involved in the catabolism of the rings C and D of cholesterol. Catalyzes the ATP-dependent CoA thioesterification of 3aalpha-H-4alpha(3'-propanoate)-7abeta-methylhexahydro-1%2C5- indanedione (HIP)%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bli:BL01325 long-chain acyl-CoA synthetase gene gene1321 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01322 S100027_01323 S100027_01323 S100027_01323 1269545 1270099 - putative MFS-type transporter YhjO Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene1322 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01323 S100027_01324 S100027_01324 S100027_01324 1270335 1271576 - hypothetical protein gene gene1323 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01324 S100027_01325 S100027_01325 S100027_01325 1271659 1273026 - Heme sensor protein HssS ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Virulence%3B Member of the two-component regulatory system HssS/HssR involved in intracellular heme homeostasis and tempering of staphylococcal virulence. HssS functions as a heme sensor histidine kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to an aspartate residue of HssR. HssR/HssS activates the expression of hrtAB%2C an efflux pump%2C in response to extracellular heme%2C hemin%2C hemoglobin or blood (By similarity)%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: bli:BL01322 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene1324 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01325 S100027_01326 S100027_01326 S100027_01326 1273023 1273697 - Transcriptional regulatory protein WalR Activator%3B Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system WalK/WalR that regulates genes involved in autolysis%2C biofilm formation and cell wall metabolism%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene1325 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01326 S100027_01327 S100027_01327 S100027_01327 1273787 1274227 - uncharacterized protein gene gene1326 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01327 S100027_01328 S100027_01328 S100027_01328 1274431 1275225 + Putative ABC transporter substrate-binding lipoprotein YvgL Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Belongs to the bacterial solute-binding protein 1 family gene gene1327 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01328 S100027_01329 S100027_01329 S100027_01329 1275234 1275890 + Putative molybdenum transport system permease protein YvgM Cell membrane%3B Membrane%3B Molybdenum%3B Transmembrane%3B Transmembrane helix%3B Transport%3B could be part of the binding-protein-dependent transport system for molybdenu%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1328 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01329 S100027_01330 S100027_01330 addB addB 1276000 1279500 + ATP-dependent helicase/deoxyribonuclease subunit 4Fe-4S%3B ATP-binding%3B DNA damage%3B DNA repair%3B Exonuclease%3B Hydrolase%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Nuclease%3B Nucleotide-binding%3B The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent%2C dual-direction single-stranded exonuclease%3B this subunit has 5' -> 3' nuclease activity%3B Belongs to the helicase family. AddB/RexB type 1 subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: bli:BL01351 ATP-dependent helicase/nuclease subunit B%3B Acting on ester bonds gene gene1329 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01330 S100027_01331 S100027_01331 addA addA 1279487 1283179 + ATP-dependent helicase/nuclease subunit ATP-binding%3B DNA damage%3B DNA repair%3B DNA-binding%3B Exonuclease%3B Helicase%3B Hydrolase%3B Nuclease%3B Nucleotide-binding%3B The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent%2C dual-direction single-stranded exonuclease%3B this subunit has the helicase and 3' -> 5' nuclease activities%3B Belongs to the helicase family. AddA subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: bli:BL01350 ATP-dependent helicase/nuclease subunit A%3B Acting on ester bonds gene gene1330 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01331 S100027_01332 S100027_01332 S100027_01332 1283244 1284425 + Nuclease SbcCD subunit Coiled coil%3B DNA recombination%3B Exonuclease%3B Hydrolase%3B Nuclease%3B SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity (By similarity)%3B Belongs to the SbcD family%3B overlaps another CDS with the same product name gene gene1331 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01332 S100027_01333 S100027_01333 S100027_01333 1284422 1287814 + Nuclease SbcCD subunit ATP-binding%3B Coiled coil%3B DNA recombination%3B DNA replication%3B Endonuclease%3B Exonuclease%3B Hydrolase%3B Nuclease%3B Nucleotide-binding%3B SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity (By similarity)%3B Belongs to the SMC family. SbcC subfamily%3B overlaps another CDS with the same product name gene gene1332 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01333 S100027_01334 S100027_01334 S100027_01334 1287858 1288076 - putative spore germination protein GerPF Germination%3B Sporulation%3B Required for the formation of functionally normal spores. Could be involved in the establishment of normal spore coat structure and/or permeability%2C which allows the access of germinants to their receptor. Belongs to the GerPA/GerPF family gene gene1333 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01334 S100027_01335 S100027_01335 S100027_01335 1288132 1288518 - putative spore germination protein GerPE Germination%3B Sporulation. gene gene1334 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01335 S100027_01336 S100027_01336 S100027_01336 1288515 1288694 - putative spore germination protein GerPD Germination%3B Sporulation. gene gene1335 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01336 S100027_01337 S100027_01337 S100027_01337 1288691 1289296 - putative spore germination protein GerPC Germination%3B Sporulation. gene gene1336 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01337 S100027_01338 S100027_01338 S100027_01338 1289317 1289559 - putative spore germination protein GerPB Germination%3B Sporulation. gene gene1337 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01338 S100027_01339 S100027_01339 S100027_01339 1289571 1289792 - putative spore germination protein GerPA Germination%3B Sporulation%3B Required for the formation of functionally normal spores. Could be involved in the establishment of normal spore coat structure and/or permeability%2C which allows the access of germinants to their receptor. Belongs to the GerPA/GerPF family gene gene1338 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01339 S100027_01340 S100027_01340 S100027_01340 1289974 1290267 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1339 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01340 S100027_01341 S100027_01341 S100027_01341 1290349 1290531 - Aspartyl-phosphate phosphatase YisI Hydrolase%3B Sporulation%3B Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation%3B Belongs to the spo0E family gene gene1340 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01341 S100027_01342 S100027_01342 S100027_01342 1290695 1291768 - Inner spore coat protein Sporulation%3B Involved in the assembly of several proteins in the inner and outer layer of the spore coat. Stabilizes CotC and CotU in the mother cell compartment of sporulating cells and promotes the assembly of both early and late forms of CotC-related polypeptides on the spore surface%3B Belongs to the CotH family gene gene1341 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01342 S100027_01343 S100027_01343 S100027_01343 1291934 1292440 + hypothetical protein gene gene1342 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01343 S100027_01344 S100027_01344 S100027_01344 1292593 1293498 + Acylpyruvate hydrolase Metal-binding%3B Belongs to the FAH family%3B KEGG: fal:FRAAL6170 acylpyruvate hydrolase gene gene1343 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01344 S100027_01345 S100027_01345 S100027_01345 1293514 1293624 + hypothetical protein gene gene1344 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01345 S100027_01346 S100027_01346 rsgA rsgA 1293768 1294820 + Putative ribosome bioproteinis GTPase RsgA GTP-binding%3B Hydrolase%3B Metal-binding%3B Nucleotide-binding%3B Plasmid%3B Zinc%3B May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover%3B Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily%3B Contains 1 CP-type G (guanine nucleotide-binding) domain%3B KEGG: bli:BL01344 ribosome biogenesis GTPase%3B In phosphorus-containing anhydrides gene gene1345 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01346 S100027_01347 S100027_01347 S100027_01347 1294840 1295310 + UPF0344 protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0344 family gene gene1346 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01347 S100027_01348 S100027_01348 S100027_01348 1295350 1295916 - uncharacterized protein gene gene1347 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01348 S100027_01349 S100027_01349 asnB asnB 1296081 1297922 + Asparagine synthase (glutamine-hydrolyzing) Amino-acid biosynthesis%3B Asparagine biosynthesis%3B ATP-binding%3B Glutamine amidotransferase%3B Ligase%3B Nucleotide-binding%3B Sporulation%3B Asparagine synthetase involved in sporulation. Belongs to the asparagine synthetase family%3B Contains 1 glutamine amidotransferase type-2 domain%3B KEGG: ppw:PputW619_2683 asparagine synthase (glutamine-hydrolysing) gene gene1348 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01349 S100027_01350 S100027_01350 S100027_01350 1298054 1298884 - Putative ammonium transporter Ammonia transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the ammonia transporter channel (TC 1. A. 11. 2) family gene gene1349 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01350 S100027_01351 S100027_01351 S100027_01351 1298951 1299433 - Putative ammonium transporter Ammonia transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the ammonia transporter channel (TC 1. A. 11. 2) family gene gene1350 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01351 S100027_01352 S100027_01352 S100027_01352 1299491 1299832 - Nitrogen regulatory protein P-II Nucleotide-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B In nitrogen-limiting conditions%2C when the ratio of Gln to 2-ketoglutarate decreases%2C P-II is uridylylated to P-II-UMP. P- II-UMP allows the deadenylation of glutamine synthetase (GS)%2C thus activating the enzyme. Conversely%2C in nitrogen excess P-II is deuridylated and promotes the adenylation of GS. P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate%2C the transcriptional activator of glnA. When P-II is uridylylated to P- II-UMP%2C these events are reversed (By similarity)%3B Belongs to the P(II) protein family gene gene1351 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01352 S100027_01353 S100027_01353 S100027_01353 1300035 1301375 - putative transporter YisQ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the multi antimicrobial extrusion (MATE) (TC 2. A. 66. 1) family gene gene1352 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01353 S100027_01354 S100027_01354 S100027_01354 1301497 1302360 + putative HTH-type transcriptional regulator YisR DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH araC/xylS-type DNA-binding domain gene gene1353 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01354 S100027_01355 S100027_01355 S100027_01355 1302389 1302946 + Putative ribosomal N-acetyltransferase YdaF Acyltransferase%3B Transferase%3B Putative N-acetyltransferase. May act on ribosomal proteins (Potential)%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK1895 null%3B Transferring groups other than amino-acyl groups gene gene1354 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01355 S100027_01356 S100027_01356 S100027_01356 1303003 1304046 + HTH-type transcriptional regulator DegA Activator%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Involved in the control of degradation of B. subtilis amidophosphoribosyltransferase (purF). Probably activates the gene for a degradative protease. Contains 1 HTH lacI-type DNA-binding domain gene gene1355 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01356 S100027_01357 S100027_01357 iolX iolX 1304214 1304774 + Scyllo-inositol 2-dehydrogenase (NAD(+)) NAD%3B Oxidoreductase%3B Catalyzes the NAD(+)-dependent oxidation of scyllo- inositol to 2%2C4%2C6/3%2C5-pentahydroxycyclohexanone (scyllo-inosose)%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: bli:BL01338 scyllo-inositol 2-dehydrogenase (NAD+)%3B overlaps another CDS with the same product name gene gene1356 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01357 S100027_01358 S100027_01358 S100027_01358 1304774 1305241 + Scyllo-inositol 2-dehydrogenase (NAD(+)) NAD%3B Oxidoreductase%3B Catalyzes the NAD(+)-dependent oxidation of scyllo- inositol to 2%2C4%2C6/3%2C5-pentahydroxycyclohexanone (scyllo-inosose)%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: bli:BL01338 scyllo-inositol 2-dehydrogenase (NAD+)%3B overlaps another CDS with the same product name gene gene1357 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01358 S100027_01359 S100027_01359 S100027_01359 1305333 1306118 + putative HTH-type transcriptional regulator YisV Aminotransferase%3B DNA-binding%3B Pyridoxal phosphate%3B Transcription%3B Transcription regulation%3B Transferase%3B In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene1358 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01359 S100027_01360 S100027_01360 ectB ectB 1306405 1307751 + Diaminobutyrate--2-oxoglutarate transaminase Aminotransferase%3B Pyridoxal phosphate%3B Transferase%3B Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bli:BL01336 diaminobutyrate-2-oxoglutarate transaminase gene gene1359 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01360 S100027_01361 S100027_01361 S100027_01361 1307735 1309246 + Diaminobutyrate decarboxylase Decarboxylase%3B Lyase%3B Pyridoxal phosphate%3B Belongs to the group II decarboxylase family%3B KEGG: bli:BL01335 L-2%2C4-diaminobutyrate decarboxylase gene gene1360 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01361 S100027_01362 S100027_01362 iucA iucA 1309243 1311009 + N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase Plasmid%3B Belongs to the IucA family%3B KEGG: vcy:IX92_17045 N2-citryl-N6-acetyl-N6-hydroxylysine synthase gene gene1361 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01362 S100027_01363 S100027_01363 iucB iucB 1311006 1311560 + N(6)-hydroxylysine O-acetyltransferase Plasmid%3B Belongs to the IucB family%3B KEGG: bba:Bd1575 acetyl CoA:N6-hydroxylysine acetyl transferase gene gene1362 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01363 S100027_01364 S100027_01364 iucD iucD 1311535 1312878 + L-lysine N(6)-monooxygenase (NADPH) FAD%3B Flavoprotein%3B NADP%3B Oxidoreductase%3B Plasmid%3B Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family%3B KEGG: bpu:BPUM_1023 lysine N6-hydroxylase gene gene1363 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01364 S100027_01365 S100027_01365 iucC iucC 1312895 1314709 + Aerobactin synthase Plasmid%3B Belongs to the IucC family%3B KEGG: pam:PANA_0352 aerobactin synthase gene gene1364 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01365 S100027_01366 S100027_01366 S100027_01366 1314752 1315192 - putative N-acetyltransferase YitI Acyltransferase%3B Transferase%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bba:Bd0335 null%3B Transferring groups other than amino-acyl groups gene gene1365 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01366 S100027_01367 S100027_01367 S100027_01367 1315357 1316190 - 3-oxoacyl-[acyl-carrier-protein] reductase Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B NADP%3B Oxidoreductase%3B Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products%2C the first reductive step in the elongation cycle of fatty acid biosynthesis%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: sehc:A35E_00575 3-oxoacyl-(acyl-carrier protein) reductase gene gene1366 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01367 S100027_01368 S100027_01368 S100027_01368 1316302 1317264 + putative HTH-type transcriptional regulator YobV Cytoplasm%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH deoR-type DNA-binding domain gene gene1367 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01368 S100027_01369 S100027_01369 metH metH 1317339 1320755 - Methionine synthase Amino-acid biosynthesis%3B Cobalamin%3B Cobalt%3B Metal-binding%3B Methionine biosynthesis%3B Methyltransferase%3B Repeat%3B S-adenosyl-L-methionine%3B Transferase%3B Zinc%3B Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine%2C yielding enzyme-bound cob(I)alamin and methionine. Subsequently%2C remethylates the cofactor using methyltetrahydrofolate (By similarity)%3B Belongs to the vitamin-B12 dependent methionine synthase family%3B Contains 1 AdoMet activation domain%3B Contains 1 B12-binding domain%3B Contains 1 B12-binding N-terminal domain%3B Contains 1 Hcy-binding domain%3B Contains 1 pterin-binding domain%3B KEGG: bli:BL01308 5-methyltetrahydrofolate--homocysteine methyltransferase gene gene1368 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01369 S100027_01370 S100027_01370 S100027_01370 1320748 1322577 - Homocysteine S-methyltransferase Amino-acid biosynthesis%3B FAD%3B Flavoprotein%3B Metal-binding%3B Methionine biosynthesis%3B Methyltransferase%3B NAD%3B NADP%3B Oxidoreductase%3B S-adenosyl-L-methionine%3B Transferase%3B Zinc%3B In the C-terminal sectio%3B belongs to the methylenetetrahydrofolate reductase family%3B Contains 1 Hcy-binding domain%3B KEGG: bli:BL01307 homocysteine S-methyltransferase gene gene1369 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01370 S100027_01371 S100027_01371 S100027_01371 1322847 1323338 - UPF0234 protein Belongs to the UPF0234 family gene gene1370 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01371 S100027_01372 S100027_01372 S100027_01372 1323502 1324350 + uncharacterized protein Contains 1 S1 motif domain gene gene1371 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01372 S100027_01373 S100027_01373 S100027_01373 1324389 1324511 - hypothetical protein gene gene1372 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01373 S100027_01374 S100027_01374 S100027_01374 1324665 1324871 + hypothetical protein gene gene1373 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01374 S100027_01375 S100027_01375 S100027_01375 1324912 1325772 - DegV domain-containing protein YitS Lipid-binding%3B May bind long-chain fatty acids%2C such as palmitate%2C and may play a role in lipid transport or fatty acid metabolism%3B Contains 1 DegV domain gene gene1374 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01375 S100027_01376 S100027_01376 S100027_01376 1325936 1326778 + UPF0750 membrane protein YitT Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0750 family gene gene1375 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01376 S100027_01377 S100027_01377 S100027_01377 1326794 1327246 + Intracellular proteinase inhibitor Cytoplasm%3B Protease inhibitor%3B Serine protease inhibitor. gene gene1376 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01377 S100027_01378 S100027_01378 guaC guaC 1327346 1328326 - GMP reductase NADP%3B Oxidoreductase%3B Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase%2C nucleoside and nucleotide derivatives of G to A nucleotides%2C and in maintaining the intracellular balance of A and G nucleotides%3B Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily%3B KEGG: bsu:BSU32130 GMP reductase gene gene1377 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01378 S100027_01379 S100027_01379 S100027_01379 1328505 1328693 - uncharacterized protein gene gene1378 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01379 S100027_01380 S100027_01380 S100027_01380 1328932 1329744 - Putative phosphatase YitU Hydrolase%3B Magnesium%3B Metal-binding%3B Belongs to the HAD-like hydrolase superfamily. Cof family gene gene1379 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01380 S100027_01381 S100027_01381 S100027_01381 1329867 1330634 + Esterase Hydrolase%3B Displays esterase activity toward palmitoyl-CoA and pNP- butyrate gene gene1380 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01381 S100027_01382 S100027_01382 S100027_01382 1330697 1331005 + MIP18 family protein YitW Belongs to the MIP18 family gene gene1381 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01382 S100027_01383 S100027_01383 argC argC 1331347 1332384 + N-acetyl-gamma-glutamyl-phosphate reductase Amino-acid biosynthesis%3B Arginine biosynthesis%3B Cytoplasm%3B NADP%3B Oxidoreductase%3B Belongs to the NAGSA dehydrogenase family. Type 1 subfamily%3B KEGG: hhc:M911_03575 N-acetyl-gamma-glutamyl-phosphate reductase gene gene1382 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01383 S100027_01384 S100027_01384 argJ argJ 1332404 1333624 + Glutamate N-acetyltransferase Acyltransferase%3B Amino-acid biosynthesis%3B Arginine biosynthesis%3B Autocatalytic cleavage%3B Cytoplasm%3B Multifunctional enzyme%3B Transferase%3B Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor%2C and of ornithine by transacetylation between N(2)-acetylornithine and glutamate%3B Belongs to the ArgJ family%3B KEGG: bli:BL03242 glutamate N-acetyltransferase / amino-acid N-acetyltransferase gene gene1383 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01384 S100027_01385 S100027_01385 argB argB 1333639 1334415 + Acetylglutamate kinase Amino-acid biosynthesis%3B Arginine biosynthesis%3B ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the acetylglutamate kinase family%3B KEGG: bsu:BSU11210 acetylglutamate kinase gene gene1384 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01385 S100027_01386 S100027_01386 argD argD 1334412 1335569 + Acetylornithine transaminase Amino-acid biosynthesis%3B Aminotransferase%3B Arginine biosynthesis%3B Cytoplasm%3B Pyridoxal phosphate%3B Transferase%3B Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily%3B KEGG: bli:BL03244 acetylornithine aminotransferase gene gene1385 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01386 S100027_01387 S100027_01387 carA carA 1335636 1336700 + Carbamoyl-phosphate synthase (glutamine-hydrolyzing) Amino-acid biosynthesis%3B Arginine biosynthesis%3B ATP-binding%3B Glutamine amidotransferase%3B Ligase%3B Nucleotide-binding%3B Belongs to the CarA family%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: bba:Bd0856 carbamoyl-phosphate synthase small subunit%3B overlaps another CDS with the same product name gene gene1386 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01387 S100027_01388 S100027_01388 carB carB 1336693 1339782 + Carbamoyl-phosphate synthase (glutamine-hydrolyzing) Amino-acid biosynthesis%3B Arginine biosynthesis%3B ATP-binding%3B Ligase%3B Magnesium%3B Manganese%3B Metal-binding%3B Nucleotide-binding%3B Pyrimidine biosynthesis%3B Repeat%3B Belongs to the CarB family%3B Contains 2 ATP-grasp domains%3B KEGG: dav:DESACE_04490 carbamoyl-phosphate synthase large subunit%3B overlaps another CDS with the same product name gene gene1387 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01388 S100027_01389 S100027_01389 argF argF 1339770 1340720 + Ornithine carbamoyltransferase Amino-acid biosynthesis%3B Arginine biosynthesis%3B Cytoplasm%3B Transferase%3B Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline%3B Belongs to the ATCase/OTCase family%3B KEGG: bli:BL03247 ornithine carbamoyltransferase gene gene1388 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01389 S100027_01390 S100027_01390 bacA bacA 1340754 1341566 - Undecaprenyl-diphosphate phosphatase Antibiotic resistance%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Membrane%3B Peptidoglycan synthesis%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin%3B Belongs to the UppP family%3B KEGG: nma:NMA2077 undecaprenyl-diphosphatase gene gene1389 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01390 S100027_01391 S100027_01391 S100027_01391 1341748 1341927 + uncharacterized protein gene gene1390 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01391 S100027_01392 S100027_01392 S100027_01392 1341999 1342193 - putative membrane protein YjzD Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1391 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01392 S100027_01393 S100027_01393 S100027_01393 1342425 1343159 + uncharacterized protein gene gene1392 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01393 S100027_01394 S100027_01394 S100027_01394 1343246 1343821 + uncharacterized protein gene gene1393 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01394 S100027_01395 S100027_01395 S100027_01395 1343908 1344861 + Transcriptional activator protein med Activator%3B Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transcription%3B Transcription regulation%3B Positive activator of the comK gene. Belongs to the BMP lipoprotein family gene gene1394 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01395 S100027_01396 S100027_01396 S100027_01396 1344872 1345057 + ComG operon repressor Competence%3B Repressor%3B Transcription%3B Transcription regulation%3B Negatively regulates the transcription of the comG operon gene gene1395 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01396 S100027_01397 S100027_01397 S100027_01397 1345109 1345348 - uncharacterized protein gene gene1396 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01397 S100027_01398 S100027_01398 S100027_01398 1345518 1346456 + Beta-ketoacyl-[acyl-carrier-protein] synthase III Acyltransferase%3B Cytoplasm%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Multifunctional enzyme%3B Transferase%3B Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Has some substrate specificity for branched chain acyl-CoA%2C determining the biosynthesis of branched-chain of fatty acids instead of straight-chain%3B Belongs to the FabH family%3B KEGG: bsu:BSU11330 3-oxoacyl-(acyl-carrier-protein) synthase III gene gene1397 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01398 S100027_01399 S100027_01399 fabF fabF 1346478 1347716 + Beta-ketoacyl-[acyl-carrier-protein] synthase II Acyltransferase%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Transferase%3B Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthesis (By similarity)%3B Belongs to the beta-ketoacyl-ACP synthases family%3B KEGG: spe:Spro_1749 3-oxoacyl-(acyl-carrier-protein) synthase II gene gene1398 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01399 S100027_01400 S100027_01400 S100027_01400 1347804 1348592 + uncharacterized protein gene gene1399 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01400 S100027_01401 S100027_01401 S100027_01401 1348784 1349758 + Oligopeptide transport ATP-binding protein AppD ATP-binding%3B Cell membrane%3B Competence%3B Membrane%3B Nucleotide-binding%3B Peptide transport%3B Protein transport%3B Sporulation%3B Transport%3B This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence%2C though%2C unlike OPP%2C is incapable of transporting tripeptides. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene1400 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01401 S100027_01402 S100027_01402 S100027_01402 1349762 1350784 + Oligopeptide transport ATP-binding protein AppF ATP-binding%3B Cell membrane%3B Competence%3B Membrane%3B Nucleotide-binding%3B Peptide transport%3B Protein transport%3B Sporulation%3B Transport%3B This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence%2C though%2C unlike OPP%2C is incapable of transporting tripeptides. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene1401 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01402 S100027_01403 S100027_01403 S100027_01403 1350897 1352528 + Oligopeptide-binding protein AppA Cell membrane%3B Competence%3B Lipoprotein%3B Membrane%3B Palmitate%3B Peptide transport%3B Protein transport%3B Signal%3B Sporulation%3B Transport%3B This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence. AppA can bind and transport tetra- and pentapeptides but not tripeptides. Belongs to the bacterial solute-binding protein 5 family gene gene1402 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01403 S100027_01404 S100027_01404 S100027_01404 1352634 1353554 + Oligopeptide transport system permease protein AppB Cell membrane%3B Competence%3B Membrane%3B Peptide transport%3B Protein transport%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence%2C though%2C unlike OPP%2C is incapable of transporting tripeptides. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1403 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01404 S100027_01405 S100027_01405 S100027_01405 1353573 1354487 + Oligopeptide transport system permease protein AppC Cell membrane%3B Competence%3B Membrane%3B Peptide transport%3B Protein transport%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence%2C though%2C unlike OPP%2C is incapable of transporting tripeptides. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1404 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01405 S100027_01406 S100027_01406 S100027_01406 1355007 1356359 + hypothetical protein gene gene1405 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01406 S100027_01407 S100027_01407 S100027_01407 1356352 1356909 + Phosphopantothenoylcysteine decarboxylase Flavoprotein%3B FMN%3B Lyase%3B Plasmid%3B Catalyzes the removal of two reducing equivalents (oxidative decarboxylation) from the cysteine residue of the C- terminal meso-lanthionine of epidermin to form a --C%3D%3DC-- double bond. Belongs to the HFCD (homooligomeric flavin containing Cys decarboxylase) superfamily%3B KEGG: sul:SYO3AOP1_1251 phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase gene gene1406 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01407 S100027_01408 S100027_01408 S100027_01408 1356942 1358207 + hypothetical protein gene gene1407 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01408 S100027_01409 S100027_01409 S100027_01409 1358422 1359174 + UPF0736 protein Belongs to the UPF0736 family gene gene1408 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01409 S100027_01410 S100027_01410 warS warS 1359418 1360410 - Tryptophan--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: bex:A11Q_1236 tryptophanyl-tRNA synthetase gene gene1409 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01410 S100027_01411 S100027_01411 S100027_01411 1361148 1362773 + Oligopeptide-binding protein OppA Cell membrane%3B Competence%3B Lipoprotein%3B Membrane%3B Palmitate%3B Peptide transport%3B Phosphoprotein%3B Protein transport%3B Signal%3B Sporulation%3B Transport%3B This protein is a component of the oligopeptide permease%2C a binding protein-dependent transport system%2C It binds peptides up to five amino acids long with high affinity. Also required for sporulation and competence. Belongs to the bacterial solute-binding protein 5 family gene gene1410 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01411 S100027_01412 S100027_01412 S100027_01412 1362869 1363804 + Dipeptide transport system permease protein DppB Cell membrane%3B Membrane%3B Peptide transport%3B Protein transport%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system for dipeptide%3B probably responsible for the translocation of the substrate across the membrane. Is expressed to facilitate adaptation to nutrient deficiency conditions. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1411 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01412 S100027_01413 S100027_01413 S100027_01413 1363809 1364726 + Oligopeptide transport system permease protein OppC Cell membrane%3B Competence%3B Membrane%3B Peptide transport%3B Protein transport%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system for oligopeptide%3B probably responsible for the translocation of the substrate across the membrane. Also required for sporulation and competence. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1412 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01413 S100027_01414 S100027_01414 S100027_01414 1364740 1365807 + Glutathione import ATP-binding protein GsiA ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Repeat%3B Transport%3B Part of the ABC transporter complex GsiABCD involved in glutathione import. Responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily. Glutathione importer (TC 3. A. 1. 5. 11) family%3B Contains 2 ABC transporter domains gene gene1413 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01414 S100027_01415 S100027_01415 S100027_01415 1365809 1366732 + Oligopeptide transport ATP-binding protein AmiF ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Peptide transport%3B Protein transport%3B Transport%3B Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene1414 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01415 S100027_01416 S100027_01416 S100027_01416 1366963 1367541 + Putative acetyltransferase YjbC Acyltransferase%3B Cytoplasm%3B Transferase%3B Contains 1 N-acetyltransferase domain gene gene1415 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01416 S100027_01417 S100027_01417 S100027_01417 1367719 1368114 + Regulatory protein Spx Cytoplasm%3B Disulfide bond%3B Redox-active center%3B Transcription%3B Transcription regulation%3B Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis%2C during periods of extreme stress%3B Belongs to the ArsC family. Spx subfamily gene gene1416 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01417 S100027_01418 S100027_01418 S100027_01418 1368337 1368999 - putative membrane protein YjbE Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the TerC family gene gene1417 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01418 S100027_01419 S100027_01419 S100027_01419 1369285 1369923 + Adapter protein MecA Competence%3B Sporulation%3B Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed%2C inhibits sporulation. Also involved in Spx degradation by ClpC (By similarity)%3B Belongs to the MecA family gene gene1418 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01419 S100027_01420 S100027_01420 S100027_01420 1370049 1371098 + UPF0065 protein YflP Signal%3B Belongs to the UPF0065 (bug) family gene gene1419 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01420 S100027_01421 S100027_01421 S100027_01421 1371201 1371656 + hypothetical protein gene gene1420 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01421 S100027_01422 S100027_01422 S100027_01422 1371679 1373184 + putative 52.8 kDa protein in TAR-I ttuC' 3'region Plasmid. gene gene1421 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01422 S100027_01423 S100027_01423 S100027_01423 1373204 1373920 - Transcriptional regulatory protein CitT Activator%3B Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system CitT/CitS. Regulates the expression of the citM-yflN operon. Phosphorylated CitT binds to the citM promoter to activate the transcription of the citM-yflN operon%3B Contains 1 response regulatory domain gene gene1422 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01423 S100027_01424 S100027_01424 S100027_01424 1373943 1375538 - Histidine kinase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system DcuR/DcuS. Involved in the C4-dicarboxylate-stimulated regulation of the genes encoding the anaerobic fumarate respiratory system (frdABC%3B nuoA%3B dcu%3B dcu%3B sdhCDA%3B etc.). Weakly regulates the aerobic C4-dicarboxylate transporter dctA. Activates DcuR by phosphorylation (By similarity)%3B Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bli:BL03342 two-component system%2C CitB family%2C sensor kinase gene gene1423 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01424 S100027_01425 S100027_01425 S100027_01425 1375656 1376804 + Putative competence protein CoiA Competence%3B Cytoplasm%3B Required for optimal transformation gene gene1424 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01425 S100027_01426 S100027_01426 S100027_01426 1376801 1378846 + Oligoendopeptidase F like protein Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Zinc%3B Belongs to the peptidase M3B family%3B KEGG: bli:BL03337 oligoendopeptidase F%3B Metalloendopeptidases gene gene1425 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01426 S100027_01427 S100027_01427 S100027_01427 1378903 1379070 - putative membrane protein YizD Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1426 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01427 S100027_01428 S100027_01428 S100027_01428 1379482 1380384 - UPF0413 protein Belongs to the UPF0413 family gene gene1427 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01428 S100027_01429 S100027_01429 S100027_01429 1380381 1380779 - Group 2 truncated hemoglobin YjbI Heme%3B Iron%3B Metal-binding%3B Transport%3B Hemoglobin-like protein that exhibits a low peroxidase activity. Its very high oxygen affinity may rule out the possibility that it is involved in oxygen transport%3B Belongs to the truncated hemoglobin family. Group II subfamily gene gene1428 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01429 S100027_01430 S100027_01430 S100027_01430 1381061 1381714 - Membrane-bound lytic murein transglycosylase Cell outer membrane%3B Cell wall biogenesis/degradation%3B Lipoprotein%3B Lyase%3B Membrane%3B Palmitate%3B Signal%3B Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division%3B Belongs to the transglycosylase Slt family gene gene1429 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01430 S100027_01431 S100027_01431 S100027_01431 1381727 1382299 - Glutathione transferase Hydrolase%3B Contains 1 CYTH domain%3B KEGG: sar:SAR0971 glutathione S-transferase gene gene1430 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01431 S100027_01432 S100027_01432 S100027_01432 1382430 1382795 + UPF0738 protein Belongs to the UPF0738 family gene gene1431 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01432 S100027_01433 S100027_01433 S100027_01433 1382827 1383462 + GTP diphosphokinase ATP-binding%3B GTP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Functions as a (p)ppGpp synthase. In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. YjbM has probably a minor role in stringent response%3B Belongs to the RelA/SpoT family%3B KEGG: bli:BL03338 putative GTP pyrophosphokinase gene gene1432 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01433 S100027_01434 S100027_01434 ppnK ppnK 1383477 1384280 + NAD(+) kinase ATP-binding%3B Cytoplasm%3B Kinase%3B NAD%3B NADP%3B Nucleotide-binding%3B Transferase%3B Involved in the regulation of the intracellular balance of NAD and NADP%2C and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP%3B Belongs to the NAD kinase family%3B KEGG: bli:BL05111 NAD+ kinase gene gene1433 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01434 S100027_01435 S100027_01435 S100027_01435 1384292 1385182 + 23S rRNA pseudouridine(1911/1915/1917) synthase Isomerase%3B Belongs to the pseudouridine synthase RluA family%3B KEGG: bli:BL01010 23S rRNA pseudouridine1911/1915/1917 synthase gene gene1434 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01435 S100027_01436 S100027_01436 apaH apaH 1385198 1385938 - Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) Hydrolase%3B Nickel%3B Asymmetrically hydrolyzes Ap4p to yield AMP and ATP%3B Belongs to the PrpE family%3B KEGG: bli:BL05112 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) gene gene1435 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01436 S100027_01437 S100027_01437 S100027_01437 1386211 1388055 + Putative Na(+)/H(+) antiporter YjbQ Antiport%3B Cell membrane%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probable Na(+)/H(+) antiporter%3B Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2. A. 37) family%3B Contains 1 RCK C-terminal domain%3B Contains 1 RCK N-terminal domain gene gene1436 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01437 S100027_01438 S100027_01438 tenA tenA 1388307 1389008 + Aminopyrimidine aminohydrolase Hydrolase%3B Thiamine biosynthesis%3B Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds%2C a reaction that is part of a thiamine salvage pathway. Thus%2C catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP). To a lesser extent%2C is also able to catalyze the hydrolytic cleavage of thiamin%3B however%2C this thiaminase activity is unlikely to be physiologically relevant. Therefore%2C is involved in the regeneration of the thiamine pyrimidine from thiamine degraded products present in the environment%2C rather than in thiamine degradation%3B Belongs to the TenA family%3B KEGG: bsu:BSU11650 thiaminase (transcriptional activator TenA) gene gene1437 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01438 S100027_01439 S100027_01439 tenI tenI 1388983 1389594 + Thiazole tautomerase Isomerase%3B Thiamine biosynthesis%3B Catalyzes the irreversible aromatization of 2-((2R%2C5Z)- 2-carboxy-4-methylthiazol-5(2H)-ylidene)ethyl phosphate (cThz*-P) to 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate (cThz-P)%2C a step in the biosynthesis of the thiazole phosphate moiety of thiamine. Cannot use cThz* as substrate%2C indicating that the phosphate group is essential. Has no thiamine phosphate synthase activity%2C despite a high sequence similarity with ThiE%3B Belongs to the thiazole tautomerase family%3B KEGG: bsu:BSU11660 thiazole tautomerase (transcriptional regulator TenI) gene gene1438 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01439 S100027_01440 S100027_01440 thiO thiO 1389551 1390687 + Glycine oxidase Cytoplasm%3B FAD%3B Flavoprotein%3B Herbicide resistance%3B Oxidoreductase%3B Thiamine biosynthesis%3B Catalyzes the FAD-dependent oxidative deamination of various amines and D-amino acids to yield the corresponding alpha- keto acids%2C ammonia/amine%2C and hydrogen peroxide. Oxidizes sarcosine (N-methylglycine)%2C N-ethylglycine and glycine. Can also oxidize the herbicide glyphosate (N-phosphonomethylglycine). Displays lower activities on D-alanine%2C D-valine%2C D-proline and D- methionine. Does not act on L-amino acids and other D-amino acids. Is essential for thiamine biosynthesis since the oxidation of glycine catalyzed by ThiO generates the glycine imine intermediate (dehydroglycine) required for the biosynthesis of the thiazole ring of thiamine pyrophosphate%3B Belongs to the DAO family%3B KEGG: bli:BL01590 glycine oxidase gene gene1439 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01440 S100027_01441 S100027_01441 S100027_01441 1390684 1390887 + Sulfur carrier protein ThiS Nucleotide-binding%3B Phosphoprotein%3B Thiamine biosynthesis%3B Is the sulfur donor in the synthesis of the thiazole phosphate moiety of thiamine phosphate%3B Belongs to the sulfur carrier protein ThiS family gene gene1440 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01441 S100027_01442 S100027_01442 thiG thiG 1390894 1391661 + Thiazole synthase Cytoplasm%3B Schiff base%3B Thiamine biosynthesis%3B Transferase%3B Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro%2C sulfur can be provided by H(2)S%3B Belongs to the ThiG family%3B KEGG: enr:H650_16535 thiazole synthase gene gene1441 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01442 S100027_01443 S100027_01443 thiF thiF 1391658 1392668 + Sulfur carrier protein ThiS adenylyltransferase ATP-binding%3B Metal-binding%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Thiamine biosynthesis%3B Transferase%3B Zinc%3B Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein ThiS%3B Belongs to the HesA/MoeB/ThiF family%3B KEGG: bsu:BSU11700 sulfur carrier protein ThiS adenylyltransferase gene gene1442 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01443 S100027_01444 S100027_01444 thiD thiD 1392693 1393511 + Hydroxymethylpyrimidine kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Thiamine biosynthesis%3B Transferase%3B Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP%2C and of HMP to HMP-P. Shows no activity with pyridoxal%2C pyridoxamine or pyridoxine%3B Belongs to the ThiD family%3B KEGG: bsu:BSU11710 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase gene gene1443 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01444 S100027_01445 S100027_01445 fabI fabI 1393668 1394444 + Enoyl-[acyl-carrier-protein] reductase (NADH) Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B NAD%3B NADP%3B Oxidoreductase%3B Stress response%3B Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily%3B KEGG: bli:BL05113 enoyl-(acyl-carrier protein) reductase I gene gene1444 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01445 S100027_01446 S100027_01446 S100027_01446 1394548 1395027 + Spore coat protein Sporulation%3B Has an important morphogenetic role. Involved in the assembly of at least five coat proteins%2C including CotB%2C CotG%2C CotS%2C CotSA and CotW. Required for appearance of a morphologically normal outer coat. To a large degree%2C CotO and CotH act at a late stage of coat assembly from within the outer coat to direct maturation of this structure gene gene1445 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01446 S100027_01447 S100027_01447 S100027_01447 1395065 1395514 - Spore coat protein Y Disulfide bond%3B Sporulation%3B To B. subtilis CotZ gene gene1446 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01447 S100027_01448 S100027_01448 S100027_01448 1395665 1396153 - Spore coat protein Y Disulfide bond%3B Sporulation%3B To B. subtilis CotZ gene gene1447 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01448 S100027_01449 S100027_01449 S100027_01449 1396285 1396797 - Spore coat protein X Sporulation. gene gene1448 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01449 S100027_01450 S100027_01450 S100027_01450 1396868 1397266 - Spore coat protein Sporulation. gene gene1449 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01450 S100027_01451 S100027_01451 S100027_01451 1397315 1397701 - Spore coat protein Sporulation. gene gene1450 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01451 S100027_01452 S100027_01452 S100027_01452 1397848 1398204 + Sporulation protein YjcA Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Involved in sporulation%3B Belongs to the UPF0713 family gene gene1451 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01452 S100027_01453 S100027_01453 S100027_01453 1398491 1398700 + hypothetical protein gene gene1452 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01453 S100027_01454 S100027_01454 S100027_01454 1398780 1398911 + UPF0752 sporulation protein YjcZ Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0752 family gene gene1453 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01454 S100027_01455 S100027_01455 S100027_01455 1399041 1399298 + Sporulation-specific transcription factor SpoVIF Cytoplasm%3B Sporulation%3B Transcription%3B Transcription regulation%3B Transcription factor involved in spore coat assembly and spore resistance. Regulates the transcription of at least cgeA%2C cotG and cotS gene gene1454 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01455 S100027_01456 S100027_01456 S100027_01456 1399337 1401619 - DNA helicase ATP-binding%3B Cytoplasm%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B May be involved in the generation of recombinogenic substrates for the subsequent action of RecA. Belongs to the helicase family. UvrD subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: bsr:I33_1319 DNA helicase II / ATP-dependent DNA helicase PcrA gene gene1455 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01456 S100027_01457 S100027_01457 S100027_01457 1401741 1401998 + uncharacterized protein gene gene1456 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01457 S100027_01458 S100027_01458 phoA phoA 1402038 1402625 - Alkaline phosphatase Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the DedA family%3B KEGG: oih:OB2407 alkaline phosphatase gene gene1457 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01458 S100027_01459 S100027_01459 S100027_01459 1402721 1403269 - UDP-glucose 4-epimerase Carbohydrate metabolism%3B Galactose metabolism%3B Isomerase%3B NAD%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: bli:BL02665 UDP-glucose 4-epimerase gene gene1458 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01459 S100027_01460 S100027_01460 S100027_01460 1403269 1403706 - UDP-arabinose 4-epimerase Isomerase%3B NAD%3B Catalyzes the interconversion between UDP-glucose and UDP-galactose%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: psd:DSC_08845 UDP-arabinose 4-epimerase gene gene1459 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01460 S100027_01461 S100027_01461 rfbA rfbA 1403703 1404593 - Glucose-1-phosphate thymidylyltransferase Carbohydrate metabolism%3B Nucleotidyltransferase%3B Transferase%3B Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG)%2C i. e. a glycolipid found in the membrane%2C which is also used as a membrane anchor for lipoteichoic acid (LTA) (By similarity)%3B Belongs to the UDPGP type 2 family%3B KEGG: eco:b2039 glucose-1-phosphate thymidylyltransferase gene gene1460 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01461 S100027_01462 S100027_01462 S100027_01462 1404616 1405011 - putative membrane protein YngA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the GtrA family gene gene1461 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01462 S100027_01463 S100027_01463 S100027_01463 1405176 1405595 - putative N-acetyltransferase YjcF Acyltransferase%3B Transferase%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK1121 null%3B Transferring groups other than amino-acyl groups gene gene1462 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01463 S100027_01464 S100027_01464 S100027_01464 1405605 1406114 - Putative phosphoesterase Hydrolase%3B Belongs to the 2H phosphoesterase superfamily. YjcG family gene gene1463 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01464 S100027_01465 S100027_01465 S100027_01465 1406179 1406901 - uncharacterized protein gene gene1464 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01465 S100027_01466 S100027_01466 S100027_01466 1407418 1407906 - hypothetical protein gene gene1465 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01466 S100027_01467 S100027_01467 S100027_01467 1407987 1408934 - putative HTH-type transcriptional regulator YobV Cytoplasm%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH deoR-type DNA-binding domain gene gene1466 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01467 S100027_01468 S100027_01468 metB metB 1409243 1410367 + Cystathionine gamma-synthase Amino-acid biosynthesis%3B Cytoplasm%3B Methionine biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Catalyzes the formation of L-cystathionine from O- acetyl-L-homoserine and L-cysteine. Can not use O-succinyl-L- homoserine as substrate. Also exhibits O-acetylhomoserine thiolyase activity%2C catalyzing the synthesis of L-homocysteine from O-acetyl-L-homoserine and sulfide%3B Belongs to the trans-sulfuration enzymes family%3B KEGG: bli:BL02660 cystathionine gamma-synthase gene gene1467 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01468 S100027_01469 S100027_01469 metC metC 1410357 1411532 + Cystathionine beta-lyase Amino-acid biosynthesis%3B Cytoplasm%3B Lyase%3B Methionine biosynthesis%3B Pyridoxal phosphate%3B Catalyzes the transformation of cystathionine into homocysteine. Also exhibits cysteine desulfhydrase activity in vitro%2C producing sulfide from cysteine%3B Belongs to the trans-sulfuration enzymes family%3B KEGG: bli:BL02659 cystathionine beta-lyase gene gene1468 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01469 S100027_01470 S100027_01470 S100027_01470 1411578 1412768 - putative membrane protein YjcL Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1469 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01470 S100027_01471 S100027_01471 S100027_01471 1412942 1413511 + hypothetical protein gene gene1470 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01471 S100027_01472 S100027_01472 S100027_01472 1413501 1413785 + hypothetical protein gene gene1471 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01472 S100027_01473 S100027_01473 S100027_01473 1413961 1415334 + Serine-type D-Ala-D-Ala carboxypeptidase Cytoplasm%3B Hydrolase%3B Acts on short-chain (C4-C6) fatty acid esters and triglycerides%2C including tertiary alcohol esters. Activity on p- nitrophenyl esters is generally higher than on o-nitrophenyl esters. Lacks beta-lactamase activit%3B it hydrolyzes the ester bond of cephalosporin substrates but there is no opening of the beta-lactam ring observed. Belongs to the class-A beta-lactamase family%3B KEGG: sth:STH2021 D-alanyl-D-alanine carboxypeptidase gene gene1472 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01473 S100027_01474 S100027_01474 S100027_01474 1415639 1416625 - Arabinan endo-1%2C5-alpha-L-arabinosidase Calcium%3B Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Metal-binding%3B Secreted%3B Signal%3B Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the internal cleavage of alpha-(1->5)-L-arabinofuranosyl residues of linear 1%2C5-alpha-L-arabinan and of branched sugar beet arabinan. It displays no activity against heavily substituted arabinans or a range of other polysaccharides (larch wood arabinogalactan%2C wheat arabinoxylan and p-nitrophenyl-alpha-L- arabinofuranoside). The enzyme activity is progressively reduced as alpha-(1->5)-chains become shorter or more highly substituted%3B Belongs to the glycosyl hydrolase 43 family%3B KEGG: bli:BL02653 arabinan endo-1%2C5-alpha-L-arabinosidase gene gene1473 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01474 S100027_01475 S100027_01475 S100027_01475 1417503 1417575 - tRNA-Val tRNA gene1474 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01475 S100027_01476 S100027_01476 S100027_01476 1417749 1417928 + hypothetical protein gene gene1475 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01476 S100027_01477 S100027_01477 S100027_01477 1417962 1418540 + Maltose O-acetyltransferase Repeat%3B Transferase%3B Acetylates maltose and other sugars. Belongs to the transferase hexapeptide repeat family%3B KEGG: eco:b0459 maltose O-acetyltransferase gene gene1476 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01477 S100027_01478 S100027_01478 S100027_01478 1418627 1418992 - hypothetical protein gene gene1477 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01478 S100027_01479 S100027_01479 S100027_01479 1419122 1420012 - HTH-type transcriptional activator AllS Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Positive regulator essential for the expression of AllD operon. Binds to the AllD promoter (By similarity)%3B Contains 1 HTH lysR-type DNA-binding domain gene gene1478 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01479 S100027_01480 S100027_01480 cysJ cysJ 1420333 1422162 + Assimilatory sulfite reductase (NADPH) Amino-acid biosynthesis%3B Cysteine biosynthesis%3B Electron transport%3B FAD%3B Flavoprotein%3B FMN%3B NADP%3B Oxidoreductase%3B Transport%3B Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component (Probable)%3B Contains 1 FAD-binding FR-type domain%3B Contains 1 flavodoxin-like domain%3B KEGG: bsu:BSU33440 sulfite reductase (NADPH) flavoprotein alpha-component gene gene1479 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01480 S100027_01481 S100027_01481 cysI cysI 1422190 1423908 + Assimilatory sulfite reductase (NADPH) 4Fe-4S%3B Amino-acid biosynthesis%3B Cysteine biosynthesis%3B Heme%3B Iron%3B Iron-sulfur%3B Metal-binding%3B NADP%3B Oxidoreductase%3B Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate%3B Belongs to the nitrite and sulfite reductase 4Fe-4S domain family%3B KEGG: bli:BL01950 sulfite reductase (NADPH) hemoprotein beta-component gene gene1480 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01481 S100027_01482 S100027_01482 S100027_01482 1423966 1424853 - putative HTH-type transcriptional regulator YoaU DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH lysR-type DNA-binding domain gene gene1481 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01482 S100027_01483 S100027_01483 S100027_01483 1424945 1425817 + putative transporter YoaV Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene1482 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01483 S100027_01484 S100027_01484 glo1 glo1 1425865 1426242 + Lactoylglutathione lyase KEGG: msu:MS0597 lactoylglutathione lyase gene gene1483 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01484 S100027_01485 S100027_01485 S100027_01485 1426286 1426834 - uncharacterized protein Signal. gene gene1484 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01485 S100027_01486 S100027_01486 S100027_01486 1427287 1428021 + N-acetylmuramoyl-L-alanine amidase Cell wall%3B Repeat%3B Secreted%3B Signal%3B Contains 2 LysM repeats%3B KEGG: beo:BEH_04935 N-acetylmuramoyl-L-alanine amidase gene gene1485 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01486 S100027_01487 S100027_01487 S100027_01487 1428077 1429501 - putative MFS-type transporter YcnB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily. EmrB family gene gene1486 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01487 S100027_01488 S100027_01488 S100027_01488 1429517 1430095 - putative HTH-type transcriptional regulator DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH tetR-type DNA-binding domain gene gene1487 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01488 S100027_01489 S100027_01489 S100027_01489 1430472 1430885 - hypothetical protein gene gene1488 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01489 S100027_01490 S100027_01490 S100027_01490 1431260 1431742 - putative antitoxin YezG Coiled coil%3B Probable antitoxin component of a toxin-antitoxin (TA) module. Probably neutralizes the ability to inhibit growth of cognate toxin YeeF. Probably does not have antitoxin activity on other toxins with the LXG toxin domain (Probable) gene gene1489 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01490 S100027_01491 S100027_01491 S100027_01491 1431746 1433470 - Ribonuclease YxiD Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene1490 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01491 S100027_01492 S100027_01492 S100027_01492 1433487 1433792 - Ribonuclease YxiD Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene1491 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01492 S100027_01493 S100027_01493 S100027_01493 1434013 1434660 + UPF0714 protein YndL Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0714 family gene gene1492 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01493 S100027_01494 S100027_01494 S100027_01494 1434674 1435330 - Phage-like element PBSX protein XkdA To B. subtilis YqaB gene gene1493 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01494 S100027_01495 S100027_01495 S100027_01495 1435519 1435872 - Repressor LexA DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Repressor of PBSX. Binds to four sites close to its own gene. Necessary for the maintenance of the lysogenic state%3B Contains 1 HTH cro/C1-type DNA-binding domain%3B KEGG: chy:CHY_1697 repressor LexA gene gene1494 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01495 S100027_01496 S100027_01496 S100027_01496 1436045 1436305 + hypothetical protein gene gene1495 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01496 S100027_01497 S100027_01497 S100027_01497 1436295 1436591 + hypothetical protein gene gene1496 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01497 S100027_01498 S100027_01498 S100027_01498 1436592 1437422 + Phage-like element PBSX protein XkdB DNA-binding%3B To B. subtilis YqaL gene gene1497 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01498 S100027_01499 S100027_01499 S100027_01499 1437472 1438122 + Phage-like element PBSX protein XkdC ATP-binding%3B Nucleotide-binding%3B May function as a transcriptional antiterminator. To B. subtilis YqaM gene gene1498 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01499 S100027_01500 S100027_01500 S100027_01500 1438122 1438292 + hypothetical protein gene gene1499 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01500 S100027_01501 S100027_01501 S100027_01501 1438393 1438734 + Phage-like element PBSX protein XkdD gene gene1500 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01501 S100027_01502 S100027_01502 S100027_01502 1438731 1438934 + Phage-like element PBSX protein XtrA To B. subtilis YqaO gene gene1501 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01502 S100027_01503 S100027_01503 S100027_01503 1439055 1439558 + Positive control factor Activator%3B DNA-binding%3B Transcription%3B Transcription regulation. gene gene1502 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01503 S100027_01504 S100027_01504 S100027_01504 1439701 1440501 + PBSX phage terminase small subunit Viral genome packaging%3B Virus exit from host cell%3B Functions as a terminase. To B. subtilis YqaS and B. subtilis phage SPP1 terminase small subunit gene gene1503 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01504 S100027_01505 S100027_01505 S100027_01505 1440498 1441796 + PBSX phage terminase large subunit Viral genome packaging%3B Virus exit from host cell%3B Functions as a terminase. To B. subtilis YqaT and phage SPP1 terminase large subunit gene gene1504 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01505 S100027_01506 S100027_01506 S100027_01506 1441800 1443314 + uncharacterized protein Belongs to the phage portal family. PBSX subfamily gene gene1505 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01506 S100027_01507 S100027_01507 S100027_01507 1443322 1444170 + Phage-like element PBSX protein XkdF To B. subtilis YqbD gene gene1506 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01507 S100027_01508 S100027_01508 S100027_01508 1444188 1445123 + Phage-like element PBSX protein XkdG Secreted%3B Signal%3B To B. subtilis YqbE gene gene1507 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01508 S100027_01509 S100027_01509 S100027_01509 1445217 1445591 + uncharacterized protein overlaps another CDS with the same product name gene gene1508 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01509 S100027_01510 S100027_01510 S100027_01510 1445588 1445944 + uncharacterized protein To B. subtilis XkdH%3B overlaps another CDS with the same product name gene gene1509 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01510 S100027_01511 S100027_01511 S100027_01511 1445941 1446429 + Phage-like element PBSX protein XkdI To B. subtilis YqbI gene gene1510 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01511 S100027_01512 S100027_01512 S100027_01512 1446442 1446882 + Phage-like element PBSX protein XkdJ To B. subtilis YqbJ gene gene1511 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01512 S100027_01513 S100027_01513 S100027_01513 1446883 1447107 + uncharacterized protein overlaps another CDS with the same product name gene gene1512 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01513 S100027_01514 S100027_01514 S100027_01514 1447107 1448453 + uncharacterized protein Belongs to the myoviridae tail sheath protein family%3B overlaps another CDS with the same product name gene gene1513 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01514 S100027_01515 S100027_01515 S100027_01515 1448455 1448898 + Phage-like element PBSX protein XkdM To B. subtilis YqbM gene gene1514 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01515 S100027_01516 S100027_01516 S100027_01516 1449081 1449530 + uncharacterized protein To B. subtilis XkdN gene gene1515 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01516 S100027_01517 S100027_01517 S100027_01517 1449554 1449709 + uncharacterized protein gene gene1516 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01517 S100027_01518 S100027_01518 S100027_01518 1449713 1453495 + Phage-like element PBSX protein XkdO To B. subtilis YqbO gene gene1517 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01518 S100027_01519 S100027_01519 S100027_01519 1453488 1454144 + Phage-like element PBSX protein XkdP Contains 1 LysM repeat gene gene1518 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01519 S100027_01520 S100027_01520 S100027_01520 1454201 1455181 + Phage-like element PBSX protein XkdQ To B. subtilis YqbQ gene gene1519 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01520 S100027_01521 S100027_01521 S100027_01521 1455178 1455486 + Phage-like element PBSX protein XkdR To B. subtilis YqbR gene gene1520 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01521 S100027_01522 S100027_01522 S100027_01522 1455505 1455930 + Phage-like element PBSX protein XkdS To B. subtilis YqbS gene gene1521 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01522 S100027_01523 S100027_01523 S100027_01523 1455923 1456966 + Phage-like element PBSX protein XkdT Belongs to the Mu gp47/PBSX XkdT family gene gene1522 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01523 S100027_01524 S100027_01524 S100027_01524 1456953 1457873 + Phage-like element PBSX protein XkdU To B. subtilis YqcA gene gene1523 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01524 S100027_01525 S100027_01525 S100027_01525 1457887 1458273 + hypothetical protein gene gene1524 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01525 S100027_01526 S100027_01526 S100027_01526 1458289 1459494 + Phage-like element PBSX protein XkdV To B. subtilis YqcC gene gene1525 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01526 S100027_01527 S100027_01527 S100027_01527 1459532 1460563 + SPBc2 prophage-derived uncharacterized protein YomR Coiled coil. gene gene1526 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01527 S100027_01528 S100027_01528 S100027_01528 1460666 1460935 + putative 11.0 kDa protein in cwlL 5'region To B. licheniformis xpaL1 and to B. subtilis XhlA gene gene1527 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01528 S100027_01529 S100027_01529 S100027_01529 1460950 1461213 + putative 9.5 kDa protein in ORF3 5'region Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the SPP1 holin family gene gene1528 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01529 S100027_01530 S100027_01530 S100027_01530 1461264 1462328 + N-acetylmuramoyl-L-alanine amidase Cell wall biogenesis/degradation%3B Hydrolase%3B Repeat%3B Secreted%3B Signal%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B KEGG: bli:BL01582 N-acetylmuramoyl-L-alanine amidase gene gene1529 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01530 S100027_01531 S100027_01531 S100027_01531 1462349 1463779 - hypothetical protein gene gene1530 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01531 S100027_01532 S100027_01532 S100027_01532 1463974 1464651 + HTH-type transcriptional repressor RspR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Repressor of the rspAB operon. Acts by binding directly to the upstream region of rspA%3B Contains 1 HTH gntR-type DNA-binding domain gene gene1531 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01532 S100027_01533 S100027_01533 rspB rspB 1464674 1465690 + L-gulonate 5-dehydrogenase Metal-binding%3B NADP%3B Oxidoreductase%3B Zinc%3B Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the acryloyl- CoA dependent NADPH oxidation and formation of propionyl-CoA%3B Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: bli:BL03803 L-gulonate 5-dehydrogenase gene gene1532 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01533 S100027_01534 S100027_01534 uxuA uxuA 1465711 1466808 + Mannonate dehydratase Iron%3B Lyase%3B Manganese%3B Catalyzes the dehydration of D-mannonate%3B Belongs to the mannonate dehydratase family%3B KEGG: bli:BL03802 mannonate dehydratase gene gene1533 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01534 S100027_01535 S100027_01535 S100027_01535 1466784 1467632 + putative oxidoreductase UxuB Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bli:BL03801 null%3B Oxidoreductases gene gene1534 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01535 S100027_01536 S100027_01536 S100027_01536 1467659 1468672 + L-galactonate-5-dehydrogenase Metal-binding%3B NAD%3B Oxidoreductase%3B Zinc%3B Catalyzes the oxidation of L-galactonate to D- tagaturonate. Required for growth on L-galactonate as the sole carbon source. In vitro%2C can also use L-gulonate%3B Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: bli:BL03800 null%3B With NAD(+) or NADP(+) as acceptor gene gene1535 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01536 S100027_01537 S100027_01537 S100027_01537 1468725 1469996 + Hexuronate transporter Cell inner membrane%3B Cell membrane%3B Membrane%3B Signal%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Aldohexuronate transport system%3B Belongs to the major facilitator superfamily. Phthalate permease family gene gene1536 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01537 S100027_01538 S100027_01538 S100027_01538 1470286 1470459 - Stage II sporulation protein SB Sporulation%3B Antitoxin component of a toxin-antitoxin (TA) module. Antitoxin that binds cognate toxin SpoIISA and neutralizes its toxic activit%3B unlike most antitoxins it does not seem to be highly labile upon expression in E. coli%3B Belongs to the SpoIISB antitoxin family gene gene1537 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01538 S100027_01539 S100027_01539 S100027_01539 1470459 1471205 - Stage II sporulation protein SA Cell membrane%3B Membrane%3B Sporulation%3B Toxin%3B Transmembrane%3B Transmembrane helix%3B Toxic component of a toxin-antitoxin (TA) module. Its toxic activity is neutralized by cognate antitoxin SpoIISB. Expression in the absence of SpoIISB permits sporulation to stage II%2C when plasmolysis zones and holes in the peptidoglycan layer are observed%2C resulting in cell death. Lethal when synthesized during vegetative growth in the absence of SpoIISB. In E. coli both the membrane bound and soluble domain are required in cis for toxin activity%3B Belongs to the SpoIISA toxin family gene gene1538 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01539 S100027_01540 S100027_01540 S100027_01540 1471316 1472314 - putative low-affinity inorganic phosphate transporter Cell membrane%3B Membrane%3B Phosphate transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Low-affinity inorganic phosphate transport%3B Belongs to the inorganic phosphate transporter (PiT) (TC 2. A. 20) family. Pit subfamily gene gene1539 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01540 S100027_01541 S100027_01541 S100027_01541 1472327 1472944 - UPF0111 protein YkaA Belongs to the UPF0111 family gene gene1540 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01541 S100027_01542 S100027_01542 S100027_01542 1473276 1475033 + Gamma-glutamyltransferase Acyltransferase%3B Glutathione biosynthesis%3B Hydrolase%3B Protease%3B Secreted%3B Signal%3B Transferase%3B Zymogen%3B Belongs to the gamma-glutamyltransferase family%3B KEGG: bli:BL03798 gamma-glutamyltranspeptidase / glutathione hydrolase gene gene1541 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01542 S100027_01543 S100027_01543 S100027_01543 1475162 1475407 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B overlaps another CDS with the same product name gene gene1542 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01543 S100027_01544 S100027_01544 S100027_01544 1475404 1475805 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B overlaps another CDS with the same product name gene gene1543 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01544 S100027_01545 S100027_01545 S100027_01545 1475819 1477555 + Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system YesM/YesN. Probably activates YesN by phosphorylation%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: bli:BL03796 two-component system%2C sensor histidine kinase YesM gene gene1544 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01545 S100027_01546 S100027_01546 S100027_01546 1477555 1478724 + putative transcriptional regulatory protein YesN Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system YesM/YesN%3B Contains 1 HTH araC/xylS-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene1545 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01546 S100027_01547 S100027_01547 S100027_01547 1478871 1480166 + Putative ABC transporter substrate-binding protein YesO May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls%3B Belongs to the bacterial solute-binding protein 1 family gene gene1546 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01547 S100027_01548 S100027_01548 S100027_01548 1480219 1481118 + putative ABC transporter permease protein YesP Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1547 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01548 S100027_01549 S100027_01549 S100027_01549 1481122 1482015 + putative ABC transporter permease protein YesQ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1548 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01549 S100027_01550 S100027_01550 yteR yteR 1482033 1483067 + Unsaturated rhamnogalacturonyl hydrolase Cytoplasm%3B Glycosidase%3B Hydrolase%3B Catalyzes the hydrolysis of unsaturated rhamnogalacturonan disaccharide to yield unsaturated D- galacturonic acid and L-rhamnose. It cannot act on unsaturated glucuronyl hydrolase (UGL) substrates containing unsaturated D- glucuronic acid at the non-reducing terminus%2C although the active pockets of YesR and UGL are very similar%3B Belongs to the glycosyl hydrolase 105 family%3B KEGG: bli:BL03791 unsaturated rhamnogalacturonyl hydrolase gene gene1549 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01550 S100027_01551 S100027_01551 S100027_01551 1483115 1485397 + HTH-type transcriptional regulator YesS Cell membrane%3B DNA-binding%3B Membrane%3B Transcription%3B Transcription regulation%3B Transmembrane%3B Transmembrane helix%3B Probable transcription factor regulating the pathway responsible for rhamnogalacturonan depolymerization. Contains 1 HTH araC/xylS-type DNA-binding domain gene gene1550 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01551 S100027_01552 S100027_01552 S100027_01552 1485411 1486127 + Rhamnogalacturonan acetylesterase RhgT Hydrolase%3B May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls. This enzyme has a broad substrate specificity%2C and shows strong preference for glucose pentaacetate%2C beta-naphthylacetate%2C and p-nitrophenyl acetate (pNPA). Also active toward acetylated xylan%3B Belongs to the 'GDSL' lipolytic enzyme family gene gene1551 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01552 S100027_01553 S100027_01553 S100027_01553 1486114 1486806 + uncharacterized protein gene gene1552 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01553 S100027_01554 S100027_01554 S100027_01554 1486821 1487432 + uncharacterized protein gene gene1553 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01554 S100027_01555 S100027_01555 yesW yesW 1487615 1489483 + Rhamnogalacturonan endolyase Calcium%3B Cell wall biogenesis/degradation%3B Lyase%3B Metal-binding%3B Secreted%3B Signal%3B Pectinolytic enzyme that degrades type I rhamnogalacturonan from plant cell walls and releases oligosaccharide products. Degrades rhamnogalacturonan%2C polygalacturonic acid%2C pectic acid and pectin%3B Belongs to the polysaccharide lyase 11 family%3B KEGG: bli:BL03786 rhamnogalacturonan endolyase gene gene1554 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01555 S100027_01556 S100027_01556 S100027_01556 1489504 1489974 + hypothetical protein gene gene1555 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01556 S100027_01557 S100027_01557 S100027_01557 1490015 1491133 + Rhamnogalacturonan acetylesterase RhgT Hydrolase%3B May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls. This enzyme has a broad substrate specificity%2C and shows strong preference for glucose pentaacetate%2C beta-naphthylacetate%2C and p-nitrophenyl acetate (pNPA). Also active toward acetylated xylan%3B Belongs to the 'GDSL' lipolytic enzyme family gene gene1556 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01557 S100027_01558 S100027_01558 yesX yesX 1491202 1493088 + Rhamnogalacturonan exolyase Calcium%3B Cell wall biogenesis/degradation%3B Lyase%3B Metal-binding%3B Secreted%3B Signal%3B Pectinolytic enzyme that degrades type I rhamnogalacturonan from plant cell walls and releases oligosaccharide products. Degrades rhamnogalacturonan%2C polygalacturonic acid%2C pectic acid and pectin%3B Belongs to the polysaccharide lyase 11 family%3B KEGG: bli:BL03783 rhamnogalacturonan exolyase gene gene1557 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01558 S100027_01559 S100027_01559 S100027_01559 1493233 1494225 + L-glyceraldehyde 3-phosphate reductase Oxidoreductase%3B Catalyzes the stereospecific%2C NADPH-dependent reduction of L-glyceraldehyde 3-phosphate (L-GAP). The physiological role of gpr is the detoxification of L-GAP%2C which may be formed by non- enzymatic racemization of GAP. Also involved in the stress response as a methylglyoxal reductase which converts the toxic metabolite methylglyoxal to acetol in vitro and in vivo (By similarity)%3B Belongs to the shaker potassium channel beta subunit family%3B KEGG: bli:BL03782 L-glyceraldehyde 3-phosphate reductase%3B With NAD(+) or NADP(+) as acceptor gene gene1558 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01559 S100027_01560 S100027_01560 rgaE rgaE 1494242 1494886 + Rhamnogalacturonan acetylesterase Hydrolase%3B May play a role in the degradation of rhamnogalacturonan derived from plant cell walls. Probably has broad substrate specificity and may degrade several types of acetylated substrates%3B Belongs to the 'GDSL' lipolytic enzyme family%3B KEGG: adl:AURDEDRAFT_140474 rhamnogalacturonan acetylesterase gene gene1559 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01560 S100027_01561 S100027_01561 lacZ lacZ 1494883 1496880 + Beta-galactosidase Glycosidase%3B Hydrolase%3B Metal-binding%3B Zinc%3B May play a role in the degradation of rhamnogalacturonan derived from plant cell walls%3B Belongs to the glycosyl hydrolase 42 family%3B KEGG: bld:BLi01382 beta-galactosidase gene gene1560 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01561 S100027_01562 S100027_01562 S100027_01562 1497055 1499646 + uncharacterized protein gene gene1561 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01562 S100027_01563 S100027_01563 S100027_01563 1499732 1501255 + Lipoprotein LipO Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal. gene gene1562 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01563 S100027_01564 S100027_01564 S100027_01564 1501297 1502250 + Protein LplB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1563 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01564 S100027_01565 S100027_01565 S100027_01565 1502269 1503153 + Protein LplC Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1564 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01565 S100027_01566 S100027_01566 S100027_01566 1503191 1504519 - Serine/threonine exchanger SteT Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Exhibits an obligate exchange activity for serine%2C threonine and aromatic amino acids%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2. A. 3. 8) family gene gene1565 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01566 S100027_01567 S100027_01567 S100027_01567 1504839 1505792 + Putative ring-cleaving dioxygenase MhqA Aromatic hydrocarbons catabolism%3B Cytoplasm%3B Detoxification%3B Dioxygenase%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Putative ring-cleavage dioxygenase that may contribute to the degradation of aromatic compounds%3B Belongs to the extradiol ring-cleavage dioxygenase family gene gene1566 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01567 S100027_01568 S100027_01568 S100027_01568 1506185 1506547 + hypothetical protein gene gene1567 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01568 S100027_01569 S100027_01569 degP degP 1506721 1508022 - Peptidase Do Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Serine protease%3B Stress response%3B Transmembrane%3B Transmembrane helix%3B Degrades abnormal exported proteins and responsible for the propeptide processing of a natural pro-protein and for the maturation of a native protein. It also plays a prominent role in stress (heat shock%2C ethanol%2C puromycin and NaCl) resistance during active exponential growth (Probable)%3B Belongs to the peptidase S1C family%3B Contains 1 PDZ (DHR) domain%3B KEGG: blh:BaLi_c15300 serine protease Do gene gene1568 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01569 S100027_01570 S100027_01570 proC proC 1508178 1508990 + Pyrroline-5-carboxylate reductase Alternative splicing%3B Amino-acid biosynthesis%3B Cytoplasm%3B NADP%3B Oxidoreductase%3B Proline biosynthesis%3B Belongs to the pyrroline-5-carboxylate reductase family%3B KEGG: bli:BL03773 pyrroline-5-carboxylate reductase gene gene1569 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01570 S100027_01571 S100027_01571 S100027_01571 1509206 1510030 + D-aminopeptidase Aminopeptidase%3B Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Sporulation%3B Zinc%3B Hydrolyzes N-terminal residues in D-amino acid containing peptides. Among the tested substrates%2C the highest activities are with D-Ala-D-Ala and D-Ala-Gly-Gly. The physiological role is not clear. Belongs to the peptidase M55 family%3B KEGG: bsu:BSU12920 D-amino peptidase%3B Aminopeptidases gene gene1570 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01571 S100027_01572 S100027_01572 S100027_01572 1510046 1510972 + Oligopeptide transport system permease protein OppB Cell membrane%3B Competence%3B Membrane%3B Peptide transport%3B Protein transport%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system for oligopeptide%3B probably responsible for the translocation of the substrate across the membrane. Also required for sporulation and competence. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1571 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01572 S100027_01573 S100027_01573 S100027_01573 1510977 1511936 + Dipeptide transport system permease protein DppC Cell membrane%3B Membrane%3B Peptide transport%3B Protein transport%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system for dipeptide%3B probably responsible for the translocation of the substrate across the membrane. Is expressed to facilitate adaptation to nutrient deficiency conditions%2C which also induce sporulation. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1572 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01573 S100027_01574 S100027_01574 nrtC nrtC 1511944 1512942 + Oligopeptide transport ATP-binding protein AmiF ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Peptide transport%3B Protein transport%3B Transport%3B Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: azo:azo0944 nitrate/nitrite transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene1573 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01574 S100027_01575 S100027_01575 S100027_01575 1512976 1514601 + Dipeptide-binding protein DppE Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Peptide transport%3B Protein transport%3B Signal%3B Sporulation%3B Transport%3B Part of the binding-protein-dependent transport system for dipeptide%3B probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions%2C which also induce sporulation. Belongs to the bacterial solute-binding protein 5 family gene gene1574 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01575 S100027_01576 S100027_01576 ldcA ldcA 1514684 1515607 + Muramoyltetrapeptide carboxypeptidase Carboxypeptidase%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Hydrolase%3B Protease%3B Serine protease%3B May be involved in the degradation of peptidoglycan by catalyzing the cleavage of the terminal D-alanine residue from cytoplasmic murein peptides%3B Belongs to the peptidase S66 family%3B KEGG: bli:BL03766 muramoyltetrapeptide carboxypeptidase gene gene1575 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01576 S100027_01577 S100027_01577 catB catB 1515625 1516722 + Muconate cycloisomerase Cell wall biogenesis/degradation%3B Isomerase%3B Magnesium%3B Metal-binding%3B Catalyzes the epimerization of L-Ala-D-Glu to L-Ala-L- Glu and has probably a role in the metabolism of the murein peptide%2C of which L-Ala-D-Glu is a component. Is also able to catalyze the reverse reaction and the epimerization of the other Ala-X dipeptides L-Ala-L-Asp%2C L-Ala-L-Leu%2C L-Ala-L-Met%2C and L-Ala- L-Ser. Is not able to epimerize other L-Ala-X dipeptides. Is also active with L-Ser-L-Glu and%2C oddly%2C L-Pro-L-Glu%2C but not with L- Glu-L-Glu%2C L-Lys-L-Glu%2C L-Lys-L-Ala%2C or D-Ala-D-Ala%3B Belongs to the mandelate racemase/muconate lactonizing enzyme family%3B KEGG: pol:Bpro_4404 muconate cycloisomerase gene gene1576 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01577 S100027_01578 S100027_01578 S100027_01578 1516719 1517606 + Gamma-D-glutamyl-L-lysine endopeptidase Cell wall biogenesis/degradation%3B Hydrolase%3B Protease%3B Thiol protease%3B Specifically hydrolyzes gamma-D-glutamyl-L-lysine bonds in murein peptides%2C releasing L-Ala-D-Glu%3B Belongs to the peptidase C40 family%3B KEGG: bco:Bcell_3074 peptidoglycan endopeptidase LytE%3B Acting on peptide bonds (peptidases) gene gene1577 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01578 S100027_01579 S100027_01579 S100027_01579 1517626 1518639 + Putative oligopeptide transport ATP-binding protein YkfD ATP-binding%3B Hydrolase%3B Nucleotide-binding%3B Transport%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene1578 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01579 S100027_01580 S100027_01580 ddaH ddaH 1518733 1519620 - Dimethylargininase Hydrolase%3B Belongs to the DDAH family%3B KEGG: scb:SCAB_13451 dimethylargininase gene gene1579 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01580 S100027_01581 S100027_01581 S100027_01581 1519811 1520329 + Acyl-CoA hydrolase Hydrolase%3B Belongs to the acyl coenzyme A hydrolase family%3B Contains 1 HotDog ACOT-type domain%3B KEGG: ban:BA_2053 acyl-CoA hydrolase gene gene1580 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01581 S100027_01582 S100027_01582 S100027_01582 1520440 1521183 + UPF0702 transmembrane protein YkjA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0702 family gene gene1581 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01582 S100027_01583 S100027_01583 S100027_01583 1521393 1522700 + Pectate lyase Calcium%3B Lyase%3B Metal-binding%3B Secreted%3B Signal%3B Produces unsaturated products from polygalacturonate. Belongs to the polysaccharide lyase 1 family%3B KEGG: bli:BL03760 pectate lyase gene gene1582 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01583 S100027_01584 S100027_01584 S100027_01584 1522820 1523152 + Putative DNA-binding protein YizB DNA-binding. gene gene1583 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01584 S100027_01585 S100027_01585 S100027_01585 1523157 1523633 + hypothetical protein gene gene1584 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01585 S100027_01586 S100027_01586 S100027_01586 1523722 1523880 + hypothetical protein gene gene1585 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01586 S100027_01587 S100027_01587 S100027_01587 1523973 1524236 + hypothetical protein gene gene1586 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01587 S100027_01588 S100027_01588 S100027_01588 1524471 1524992 + uncharacterized protein gene gene1587 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01588 S100027_01589 S100027_01589 S100027_01589 1525202 1525531 + Multidrug resistance protein YkkC Antibiotic resistance%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of a multidrug efflux pump. Confers resistance to a broad range of toxic compounds such as cationic dyes%2C neutral and anionic antimicrobials (By similarity)%3B Belongs to the small multidrug resistance (SMR) protein family. YkkC/YkkD (TC 2. A. 7. 1. 5) subfamily gene gene1588 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01589 S100027_01590 S100027_01590 S100027_01590 1525531 1525845 + Multidrug resistance protein YkkD Antibiotic resistance%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of a multidrug efflux pump. Confers resistance to a broad range of toxic compounds such as cationic dyes%2C neutral and anionic antimicrobials (By similarity)%3B Belongs to the small multidrug resistance (SMR) protein family. YkkC/YkkD (TC 2. A. 7. 1. 5) subfamily gene gene1589 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01590 S100027_01591 S100027_01591 purU purU 1525950 1526852 + Formyltetrahydrofolate deformylase Hydrolase%3B One-carbon metabolism%3B Purine biosynthesis%3B Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)%3B Belongs to the PurU family%3B Contains 1 ACT domain%3B KEGG: bli:BL03753 formyltetrahydrofolate deformylase gene gene1590 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01591 S100027_01592 S100027_01592 proB proB 1527191 1528288 + Glutamate 5-kinase Amino-acid biosynthesis%3B ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Proline biosynthesis%3B Transferase%3B Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate%3B Belongs to the glutamate 5-kinase family%3B Contains 1 PUA domain%3B KEGG: rma:Rmag_0413 glutamate 5-kinase gene gene1591 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01592 S100027_01593 S100027_01593 proA proA 1528301 1529548 + Glutamate-5-semialdehyde dehydrogenase Amino-acid biosynthesis%3B Cytoplasm%3B NADP%3B Oxidoreductase%3B Proline biosynthesis%3B Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate%3B Belongs to the gamma-glutamyl phosphate reductase family%3B KEGG: bli:BL03751 glutamate-5-semialdehyde dehydrogenase gene gene1592 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01593 S100027_01594 S100027_01594 S100027_01594 1529659 1530081 + Organic hydroperoxide resistance protein OhrA Involved in organic hydroperoxide resistance%3B Belongs to the OsmC/Ohr family gene gene1593 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01594 S100027_01595 S100027_01595 S100027_01595 1530111 1531541 - hypothetical protein gene gene1594 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01595 S100027_01596 S100027_01596 mtaP mtaP 1531669 1532121 - S-methyl-5'-thioadenosine phosphorylase Cytoplasm%3B DNA-binding%3B Oxidation%3B Repressor%3B Transcription%3B Transcription regulation%3B Organic peroxide sensor. Represses the expression of the peroxide-inducible gene ohrA by cooperative binding to two inverted repeat elements%3B Contains 1 HTH marR-type DNA-binding domain%3B KEGG: tmr:Tmar_1098 5'-methylthioadenosine phosphorylase gene gene1595 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01596 S100027_01597 S100027_01597 S100027_01597 1532281 1532694 + Organic hydroperoxide resistance protein OhrB Stress response%3B Involved in organic hydroperoxide resistance%3B Belongs to the OsmC/Ohr family gene gene1596 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01597 S100027_01598 S100027_01598 S100027_01598 1532766 1533431 + hypothetical protein gene gene1597 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01598 S100027_01599 S100027_01599 guaD guaD 1533461 1533931 - Guanine deaminase Hydrolase%3B Metal-binding%3B Purine metabolism%3B Zinc%3B Catalyzes the hydrolytic deamination of guanine%2C producing xanthine and ammonia%3B Belongs to the cytidine and deoxycytidylate deaminase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: bli:BL03735 guanine deaminase gene gene1598 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01599 S100027_01600 S100027_01600 gpmB gpmB 1534078 1534710 + Phosphoglycerate mutase (2%2C3-diphosphoglycerate-independent) Cobalamin biosynthesis%3B Hydrolase%3B Catalyzes the conversion of adenosylcobalamin 5'- phosphate to adenosylcobalamin (vitamin B12%3B involved in the assembly of the nucleotide loop of cobalamin. Also catalyzes the hydrolysis of the phospho group from alpha-ribazole 5'-phosphate to form alpha-ribazole (By similarity)%3B Belongs to the phosphoglycerate mutase family%3B KEGG: bli:BL03733 probable phosphoglycerate mutase gene gene1599 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01600 S100027_01601 S100027_01601 S100027_01601 1534753 1535466 - hypothetical protein gene gene1600 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01601 S100027_01602 S100027_01602 S100027_01602 1535463 1535777 - hypothetical protein gene gene1601 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01602 S100027_01603 S100027_01603 metE metE 1535985 1538273 - 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase Amino-acid biosynthesis%3B Metal-binding%3B Methionine biosynthesis%3B Methyltransferase%3B Repeat%3B Transferase%3B Zinc%3B Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation%3B Belongs to the vitamin-B12 independent methionine synthase family%3B KEGG: bli:BL03738 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase gene gene1602 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01603 S100027_01604 S100027_01604 S100027_01604 1538744 1539697 - Major intracellular serine protease Cytoplasm%3B Hydrolase%3B Protease%3B Serine protease%3B Zymogen%3B Major intracellular protease produced by Bacillus subtilis. Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bli:BL03740 major intracellular serine protease%3B Serine endopeptidases gene gene1603 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01604 S100027_01605 S100027_01605 S100027_01605 1539990 1540145 + uncharacterized protein gene gene1604 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01605 S100027_01606 S100027_01606 S100027_01606 1540698 1542053 + Magnesium transporter MgtE CBS domain%3B Cell membrane%3B Magnesium%3B Membrane%3B Metal-binding%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Acts as a magnesium transporter%3B Belongs to the SLC41A transporter family%3B Contains 2 CBS domains gene gene1605 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01606 S100027_01607 S100027_01607 S100027_01607 1542146 1542553 + hypothetical protein gene gene1606 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01607 S100027_01608 S100027_01608 S100027_01608 1542584 1542916 - HTH-type transcriptional regulator TnrA Activator%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Regulator of transcription that activates or represses many genes during nitrogen-limited growt%3B among others%2C it activates nrgAB%2C nasABCDE%2C gabP%2C and represses glnRA%3B Contains 1 HTH merR-type DNA-binding domain gene gene1607 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01608 S100027_01609 S100027_01609 S100027_01609 1543109 1543264 + uncharacterized protein Coiled coil. gene gene1608 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01609 S100027_01610 S100027_01610 S100027_01610 1543371 1543550 + Stress response protein YkoL Stress response. gene gene1609 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01610 S100027_01611 S100027_01611 S100027_01611 1543492 1543587 + hypothetical protein gene gene1610 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01611 S100027_01612 S100027_01612 S100027_01612 1543724 1544185 + putative HTH-type transcriptional regulator YkoM DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH marR-type DNA-binding domain gene gene1611 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01612 S100027_01613 S100027_01613 ligD ligD 1544191 1546041 - DNA ligase (ATP) ATP-binding%3B DNA damage%3B DNA recombination%3B DNA repair%3B DNA-binding%3B DNA-directed DNA polymerase%3B Exonuclease%3B Hydrolase%3B Ligase%3B Manganese%3B Metal-binding%3B Multifunctional enzyme%3B Nuclease%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Sporulation%3B Transferase%3B Probably involved in DNA repair during spore germination%3B The preference of the polymerase domain for rNTPs over dNTPs may be advantageous in dormant cells%2C where the dNTP pool may be limiting%3B In the N-terminal sectio%3B belongs to the LigD polymerase family%3B In the C-terminal sectio%3B belongs to the ATP- dependent DNA ligase family gene gene1612 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01613 S100027_01614 S100027_01614 S100027_01614 1546045 1546917 - Non-like proteinous end joining protein Ku DNA damage%3B DNA recombination%3B DNA repair%3B DNA-binding%3B Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD (By similarity). Probably involved in DNA repair during spore germination%3B Belongs to the prokaryotic Ku family%3B Contains 1 Ku domain gene gene1613 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01614 S100027_01615 S100027_01615 S100027_01615 1547071 1548723 - putative signaling protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Contains 1 EAL domain%3B Contains 1 GGDEF domain%3B Contains 1 MHYT domain%3B KEGG: she:Shewmr4_0791 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene1614 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01615 S100027_01616 S100027_01616 S100027_01616 1549043 1549654 + putative membrane protein YkoX Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the DedA family gene gene1615 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01616 S100027_01617 S100027_01617 S100027_01617 1549926 1550693 + putative membrane protein YkoY Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the TerC family gene gene1616 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01617 S100027_01618 S100027_01618 S100027_01618 1550986 1551741 + RNA polymerase sigma factor SigI DNA-binding%3B Sigma factor%3B Stress response%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor plays a role in survival at low temperatures and could be involved in heat shock stress response%2C positively regulating the expression of genes such as bcrC and mreBH during this stress%3B Belongs to the sigma-70 factor family gene gene1617 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01618 S100027_01619 S100027_01619 S100027_01619 1551738 1552829 + Peroxiredoxin Cell membrane%3B Membrane%3B Stress response%3B Transmembrane%3B Transmembrane helix%3B Anti-sigma factor for SigI. Negatively regulates SigI activity through direct interaction%3B KEGG: smp:SMAC_05546 peroxiredoxin Q/BCP gene gene1618 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01619 S100027_01620 S100027_01620 S100027_01620 1552842 1553039 - Small%2C acid-soluble spore protein C3 DNA-binding%3B Sporulation%3B SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. Belongs to the alpha/beta-type SASP family gene gene1619 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01620 S100027_01621 S100027_01621 S100027_01621 1553170 1553889 - uncharacterized protein gene gene1620 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01621 S100027_01622 S100027_01622 htpX htpX 1554031 1554924 + Protease HtpX like protein Cell membrane%3B Hydrolase%3B Membrane%3B Metal-binding%3B Metalloprotease%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Zinc%3B Belongs to the peptidase M48B family%3B KEGG: bsu:BSU13490 heat shock protein HtpX%3B Metalloendopeptidases gene gene1621 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01622 S100027_01623 S100027_01623 S100027_01623 1555071 1556420 + Potassium/sodium uptake protein NtpJ Cell membrane%3B Ion transport%3B Membrane%3B Potassium%3B Potassium transport%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mediates electrogenic transport of potassium as well as sodium. Acts probably as a potassium-sodium cotransporter. Major sodium reentry pathway at high pH values%3B Belongs to the TrkH potassium transport family gene gene1622 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01623 S100027_01624 S100027_01624 S100027_01624 1556533 1558533 + Penicillin-binding protein Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Peptidoglycan synthesis%3B Transmembrane%3B Transmembrane helix%3B Belongs to the transpeptidase family gene gene1623 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01624 S100027_01625 S100027_01625 S100027_01625 1558581 1558796 + uncharacterized protein overlaps another CDS with the same product name gene gene1624 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01625 S100027_01626 S100027_01626 S100027_01626 1558793 1558981 + uncharacterized protein overlaps another CDS with the same product name gene gene1625 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01626 S100027_01627 S100027_01627 S100027_01627 1559034 1560059 - Putative membrane-bound acyltransferase YkrP Acyltransferase%3B Cell membrane%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Belongs to the acyltransferase 3 family gene gene1626 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01627 S100027_01628 S100027_01628 kinE kinE 1560369 1562579 + Histidine kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Phosphoprotein%3B Repeat%3B Sporulation%3B Transferase%3B Two-component regulatory system%3B Phosphorylates the sporulation-regulatory protein spo0A under biofilm growth conditions. Also able to weakly phosphorylate spo0F%3B Contains 1 histidine kinase domain%3B Contains 4 PAS (PER-ARNT-SIM) domains%3B KEGG: bli:BL03536 two-component system%2C sporulation sensor kinase E gene gene1627 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01628 S100027_01629 S100027_01629 mgmT mgmT 1562587 1563084 + Methylated-DNA--[protein]-cysteine S-methyltransferase Cytoplasm%3B DNA damage%3B DNA repair%3B Methyltransferase%3B Transferase%3B Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated%3B Belongs to the MGMT family%3B KEGG: bli:BL03537 methylated-DNA-(protein)-cysteine S-methyltransferase gene gene1628 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01629 S100027_01630 S100027_01630 S100027_01630 1563176 1563289 + hypothetical protein gene gene1629 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01630 S100027_01631 S100027_01631 mtnA mtnA 1563296 1564357 - S-methyl-5-thioribose-1-phosphate isomerase Amino-acid biosynthesis%3B Isomerase%3B Methionine biosynthesis%3B Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)%3B Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily%3B KEGG: bli:BL03632 methylthioribose-1-phosphate isomerase gene gene1630 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01631 S100027_01632 S100027_01632 mtnK mtnK 1564363 1565559 - S-methyl-5-thioribose kinase Amino-acid biosynthesis%3B ATP-binding%3B Kinase%3B Methionine biosynthesis%3B Nucleotide-binding%3B Transferase%3B Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate%3B Belongs to the methylthioribose kinase family%3B KEGG: bli:BL03633 5-methylthioribose kinase gene gene1631 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01632 S100027_01633 S100027_01633 S100027_01633 1565871 1566650 - Hydrolase MtnU Hydrolase%3B May be involved in a regulatory step in the methylthioribose (MTR) recycling pathway%3B Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family%3B Contains 1 CN hydrolase domain gene gene1632 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01633 S100027_01634 S100027_01634 mtnE mtnE 1566746 1567936 + putative aspartate aminotransferase Aminotransferase%3B Cytoplasm%3B Pyridoxal phosphate%3B Transferase%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bli:BL03539 aminotransferase%3B Transaminases gene gene1633 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01634 S100027_01635 S100027_01635 mtnW mtnW 1568170 1569387 + 2%2C3-diketo-5-methylthiopentyl-1-phosphate enolase Amino-acid biosynthesis%3B Isomerase%3B Magnesium%3B Metal-binding%3B Methionine biosynthesis%3B Catalyzes the enolization of 2%2C3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)%3B Belongs to the RuBisCO large chain family. Type IV subfamily%3B KEGG: bsu:BSU13590 2%2C3-diketo-5-methylthiopentyl-1-phosphate enolase gene gene1634 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01635 S100027_01636 S100027_01636 mtnB mtnB 1569384 1570667 + Methylthioribulose 1-phosphate dehydratase Amino-acid biosynthesis%3B Hydrolase%3B Lyase%3B Metal-binding%3B Methionine biosynthesis%3B Multifunctional enzyme%3B Zinc%3B Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2%2C3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)%3B Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1%2C2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)%3B In the N-terminal sectio%3B belongs to the HAD-like hydrolase superfamily. MtnX family%3B In the C-terminal sectio%3B belongs to the aldolase class II family. MtnB subfamily%3B KEGG: bli:BL03541 methylthioribulose-1-phosphate dehydratase gene gene1635 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01636 S100027_01637 S100027_01637 mtnD mtnD 1570688 1571227 + Acireductone dioxygenase (Ni(2+)-requiring) Amino-acid biosynthesis%3B Dioxygenase%3B Iron%3B Metal-binding%3B Methionine biosynthesis%3B Nickel%3B Oxidoreductase%3B Catalyzes 2 different reactions between oxygene and the acireductone 1%2C2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB)%2C the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate%2C carbon monoxide and formate%2C and does not lie on the methionine recycle pathway%3B Belongs to the acireductone dioxygenase (ARD) family%3B KEGG: bsu:BSU13620 1%2C2-dihydroxy-3-keto-5-methylthiopentene dioxygenase gene gene1636 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01637 S100027_01638 S100027_01638 fosB fosB 1571252 1571716 - Metallothiol transferase FosB Antibiotic resistance%3B Cytoplasm%3B Magnesium%3B Metal-binding%3B Transferase%3B Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor%3B Belongs to the fosfomycin resistance protein family. FosB subfamily%3B KEGG: bli:BL03635 metallothiol transferase%3B Transferring alkyl or aryl groups%2C other than methyl groups gene gene1637 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01638 S100027_01639 S100027_01639 S100027_01639 1571703 1572032 - putative membrane protein YkvA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1638 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01639 S100027_01640 S100027_01640 S100027_01640 1572251 1572493 + Aspartyl-phosphate phosphatase Spo0E Hydrolase%3B Sporulation%3B Transcription%3B Transcription regulation%3B Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation%3B Belongs to the spo0E family gene gene1639 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01640 S100027_01641 S100027_01641 kinD kinD 1572555 1574066 - Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Sporulation%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Phosphorylates the sporulation-regulatory protein spo0F and%2C to a minor extent%2C is responsible for heterogeneous expression of spo0A during logarithmical growth. Also phosphorylates spo0A under biofilm growth conditions%3B Contains 1 histidine kinase domain%3B KEGG: bli:BL03637 two-component system%2C sporulation sensor kinase D gene gene1640 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01641 S100027_01642 S100027_01642 S100027_01642 1574304 1574759 + HTH-type transcriptional regulator MhqR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Negatively regulates mhqA%2C mhqED%2C mhqNOP%2C and azoR2 which may contribute to the degradation of aromatic compounds%3B Contains 1 HTH marR-type DNA-binding domain gene gene1641 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01642 S100027_01643 S100027_01643 S100027_01643 1574784 1575563 - Motility protein Cell membrane%3B Chemotaxis%3B Flagellar rotation%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B MotA and MotB comprise the stator element of the flagellar motor complex. Required for the rotation of the flagellar motor. Might be a linker that fastens the torque- generating machinery to the cell wall (By similarity)%3B Belongs to the MotB family%3B Contains 1 OmpA-like domain%3B overlaps another CDS with the same product name gene gene1642 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01643 S100027_01644 S100027_01644 S100027_01644 1575556 1576359 - Motility protein Cell membrane%3B Chemotaxis%3B Flagellar rotation%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel (By similarity)%3B Belongs to the MotA family%3B overlaps another CDS with the same product name gene gene1643 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01644 S100027_01645 S100027_01645 S100027_01645 1576558 1578654 - ATP-dependent Clp protease ATP-binding subunit ClpE ATP-binding%3B Chaperone%3B Metal-binding%3B Nucleotide-binding%3B Stress response%3B Zinc%3B Zinc-finger%3B ATPase essential both for efficient CtsR-dependent gene derepression during heat stress and for rerepression. Together with ClpP%2C degrades the global regulator CtsR after heat shock. Is also involved in disaggregation of heat-denatured proteins. Has thus a role in overall protein quality control in response to heat stress%3B Belongs to the ClpA/ClpB family. ClpE subfamily%3B Contains 1 UVR domain gene gene1644 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01645 S100027_01646 S100027_01646 S100027_01646 1578875 1579909 + putative membrane protein YkvI Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1645 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01646 S100027_01647 S100027_01647 queC queC 1580174 1580833 + 7-cyano-7-deazaguanine synthase ATP-binding%3B Ligase%3B Metal-binding%3B Nucleotide-binding%3B Queuosine biosynthesis%3B Zinc%3B Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))%3B Belongs to the QueC family%3B KEGG: psh:Psest_1506 7-cyano-7-deazaguanine synthase gene gene1646 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01647 S100027_01648 S100027_01648 queD queD 1580836 1581276 + 6-pyruvoyltetrahydropterin synthase Lyase%3B Metal-binding%3B Queuosine biosynthesis%3B Zinc%3B Catalyzes the conversion of 7%2C8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5%2C6%2C7%2C8-tetrahydropterin (CPH4) and acetaldehyde%3B Belongs to the PTPS family. QueD subfamily%3B KEGG: bsu:BSU13730 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase gene gene1647 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01648 S100027_01649 S100027_01649 queE queE 1581326 1582000 + 7-carboxy-7-deazaguanine synthase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Lyase%3B Metal-binding%3B Queuosine biosynthesis%3B S-adenosyl-L-methionine%3B Catalyzes the conversion of 6-carboxy-5%2C6%2C7%2C8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG)%3B Belongs to the radical SAM superfamily. 7-carboxy-7- deazaguanine synthase family%3B KEGG: ead:OV14_a0984 7-carboxy-7-deazaguanine synthase gene gene1648 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01649 S100027_01650 S100027_01650 S100027_01650 1582022 1582519 + PreQ(1) synthase Cytoplasm%3B NADP%3B Oxidoreductase%3B Queuosine biosynthesis%3B Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)%3B Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily%3B KEGG: bsu:BSU13750 7-cyano-7-deazaguanine reductase gene gene1649 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01650 S100027_01651 S100027_01651 S100027_01651 1583192 1583317 - hypothetical protein gene gene1650 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01651 S100027_01652 S100027_01652 rapH rapH 1583307 1583588 - Response regulator aspartate phosphatase Hydrolase%3B Protein phosphatase%3B Repeat%3B Sporulation%3B TPR repeat%3B Prevents sporulation by dephosphorylating Spo0F%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: blh:BaLi_c16130 response regulator aspartate phosphatase H%3B Acting on ester bonds%3B overlaps another CDS with the same product name gene gene1651 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01652 S100027_01653 S100027_01653 S100027_01653 1583581 1583964 - Response regulator aspartate phosphatase Hydrolase%3B Protein phosphatase%3B Repeat%3B TPR repeat%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: blh:BaLi_c16130 response regulator aspartate phosphatase H%3B Acting on ester bonds%3B overlaps another CDS with the same product name gene gene1652 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01653 S100027_01654 S100027_01654 S100027_01654 1584022 1584429 - Response regulator aspartate phosphatase Hydrolase%3B Protein phosphatase%3B Repeat%3B TPR repeat%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bld:BLi01578 response regulator aspartate phosphatase H%3B Acting on ester bonds gene gene1653 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01654 S100027_01655 S100027_01655 mobA mobA 1584812 1585603 - Molybdenum cofactor guanylyltransferase Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B KEGG: lmob:BN419_1252 molybdopterin-guanine dinucleotide biosynthesis protein A gene gene1654 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01655 S100027_01656 S100027_01656 S100027_01656 1585733 1585954 - putative HTH-type transcriptional regulator YozG DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene1655 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01656 S100027_01657 S100027_01657 S100027_01657 1585965 1586447 - putative membrane protein YoaS Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1656 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01657 S100027_01658 S100027_01658 S100027_01658 1586985 1587230 - hypothetical protein gene gene1657 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01658 S100027_01659 S100027_01659 S100027_01659 1587329 1587649 - hypothetical protein gene gene1658 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01659 S100027_01660 S100027_01660 S100027_01660 1587646 1588428 - hypothetical protein gene gene1659 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01660 S100027_01661 S100027_01661 S100027_01661 1588673 1589533 - putative transposase-like protein DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene1660 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01661 S100027_01662 S100027_01662 S100027_01662 1589503 1589835 - hypothetical protein gene gene1661 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01662 S100027_01663 S100027_01663 S100027_01663 1590095 1590439 + hypothetical protein gene gene1662 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01663 S100027_01664 S100027_01664 S100027_01664 1591057 1591911 + hypothetical protein gene gene1663 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01664 S100027_01665 S100027_01665 S100027_01665 1592267 1592455 - uncharacterized protein gene gene1664 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01665 S100027_01666 S100027_01666 S100027_01666 1592622 1592816 + uncharacterized protein gene gene1665 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01666 S100027_01667 S100027_01667 S100027_01667 1593046 1593657 + N-acetylmuramoyl-L-alanine amidase Signal%3B KEGG: bsu:BSU13820 N-acetylmuramoyl-L-alanine amidase gene gene1666 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01667 S100027_01668 S100027_01668 S100027_01668 1593847 1595187 + Sporulation protein YkvU Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix. gene gene1667 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01668 S100027_01669 S100027_01669 S100027_01669 1595252 1595743 + Sporulation thiol-disulfide oxidoreductase Disulfide bond%3B Membrane%3B Oxidoreductase%3B Redox-active center%3B Signal%3B Sporulation%3B Thiol-disulfide oxidoreductase with a reductive function%2C involved in spore cortex synthesis. It could be involved either in breaking disulfide bonds in cortex components or in proteins that are important for cortex synthesis%2C or in thiol/disulfide bond interchange%3B Belongs to the thioredoxin family%3B Contains 1 thioredoxin domain gene gene1668 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01669 S100027_01670 S100027_01670 S100027_01670 1595998 1597905 + Cadmium-exporting ATPase ATP-binding%3B Cell membrane%3B Hydrolase%3B Ion transport%3B Magnesium%3B Membrane%3B Metal-binding%3B Nucleotide-binding%3B Phosphoprotein%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Zinc%3B Zinc transport%3B Couples the hydrolysis of ATP with the transport of zinc into the cell. Plays an important role in protecting cells against oxidative stress. ZosA-mediated zinc transport is required for post-transcriptional control of comK and competence development%3B Belongs to the cation transport ATPase (P-type) (TC 3. A. 3) family. Type IB subfamily%3B KEGG: bli:BL03560 Cd2+/Zn2+-exporting ATPase gene gene1669 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01670 S100027_01671 S100027_01671 pepQ pepQ 1598108 1599202 + Xaa-Pro dipeptidase Hydrolase%3B Manganese%3B Metal-binding%3B Belongs to the peptidase M24B family%3B KEGG: bsu:BSU13860 Xaa-Pro dipeptidase gene gene1670 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01671 S100027_01672 S100027_01672 S100027_01672 1599266 1599400 - hypothetical protein gene gene1671 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01672 S100027_01673 S100027_01673 S100027_01673 1599892 1600617 + hypothetical protein gene gene1672 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01673 S100027_01674 S100027_01674 S100027_01674 1600842 1601813 + Catabolite control protein DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcriptional regulator involved in catabolite repression of several operons. Contains 1 HTH lacI-type DNA-binding domain gene gene1673 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01674 S100027_01675 S100027_01675 S100027_01675 1601946 1602791 + Beta-glucoside operon antiterminator Activator%3B Phosphoprotein%3B Repeat%3B RNA-binding%3B Transcription%3B Transcription regulation%3B Mediates the positive regulation of the beta-glucoside (arb) operon by functioning as a transcriptional antiterminator. This is an RNA-binding protein that recognizes a specific sequence located just upstream of two termination sites within the operon (By similarity)%3B Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains gene gene1674 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01675 S100027_01676 S100027_01676 gamP gamP 1603013 1605109 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Kinase%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport. Contains 1 PTS EIIA type-1 domain%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bli:BL03565 PTS system%2C D-glucosamine-specific IIA component gene gene1675 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01676 S100027_01677 S100027_01677 S100027_01677 1605210 1605476 + Phosphocarrier protein Cytoplasm%3B Kinase%3B Phosphoprotein%3B Phosphotransferase system%3B Serine/threonine-protein kinase%3B Sugar transport%3B Transcription%3B Transcription regulation%3B Transferase%3B Transport%3B General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the permease (enzymes II/III). P-Ser-HPr interacts with the catabolite control protein A (CcpA)%2C forming a complex that binds to DNA at the catabolite response elements cre%2C operator sites preceding a large number of catabolite-regulated genes. Thus%2C P-Ser-HPr is a corepressor in carbon catabolite repression (CCR)%2C a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion%2C in which it probably interacts with several non-PTS permeases and inhibits their transport activity. Belongs to the HPr family%3B Contains 1 HPr domain gene gene1676 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01677 S100027_01678 S100027_01678 ptsI ptsI 1605476 1607194 + Phosphoenolpyruvate--protein phosphotransferase Cytoplasm%3B Kinase%3B Magnesium%3B Metal-binding%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transport%3B General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). Belongs to the PEP-utilizing enzyme family%3B KEGG: bsu:BSU13910 phosphotransferase system%2C enzyme I%2C PtsI gene gene1677 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01678 S100027_01679 S100027_01679 S100027_01679 1607314 1607547 + Transcriptional regulator SplA Transcription%3B Transcription regulation. gene gene1678 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01679 S100027_01680 S100027_01680 splB splB 1607525 1608649 + Spore photoproduct lyase 4Fe-4S%3B DNA damage%3B DNA repair%3B DNA-binding%3B Iron%3B Iron-sulfur%3B Lyase%3B Metal-binding%3B S-adenosyl-L-methionine%3B Sporulation%3B Involved in repair of UV radiation-induced DNA damage during spore germination. Can repair thymine dimer 5-thyminyl-5%2C6- dihydrothymine (known as spore photoproduct (SP)) by in situ monomerization of SP to two thymines%3B Belongs to the radical SAM superfamily. SPL family%3B KEGG: blh:BaLi_c16380 spore photoproduct lyase gene gene1679 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01680 S100027_01681 S100027_01681 S100027_01681 1608693 1609361 - putative N-acetyltransferase YkwB Acyltransferase%3B Transferase%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain gene gene1680 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01681 S100027_01682 S100027_01682 S100027_01682 1609475 1611442 + Methyl-accepting chemotaxis protein McpC Cell membrane%3B Chemotaxis%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpC is required for taxis to cysteine%2C proline%2C threonine%2C glycine%2C serine%2C lysine%2C valine and arginine and for aspartate%2C glutamine%2C histidine and glutamate. Primarily mediates response to positive stimulus of PTS carbohydrates. Greatly influences the duration or magnitude of the response to negative PTS carbohydrate stimulus%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene1681 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01682 S100027_01683 S100027_01683 S100027_01683 1611460 1612335 + 3-oxoacyl-[acyl-carrier-protein] reductase Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B NADP%3B Oxidoreductase%3B Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products%2C the first reductive step in the elongation cycle of fatty acid biosynthesis%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bld:BLi01605 3-oxoacyl-(acyl-carrier protein) reductase gene gene1682 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01683 S100027_01684 S100027_01684 mmsB mmsB 1612349 1613221 + 3-hydroxyisobutyrate dehydrogenase NAD%3B Oxidoreductase%3B Belongs to the 3-hydroxyisobutyrate dehydrogenase family%3B KEGG: bsr:I33_1574 3-hydroxyisobutyrate dehydrogenase gene gene1683 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01684 S100027_01685 S100027_01685 S100027_01685 1613266 1614027 - uncharacterized protein Signal%3B Contains 1 SCP domain gene gene1684 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01685 S100027_01686 S100027_01686 S100027_01686 1614375 1616483 + Penicillin-binding protein Antibiotic resistance%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Peptidoglycan synthesis%3B Transmembrane%3B Transmembrane helix%3B Involved in the polymerization of peptidoglycan. Plays a redundant role with PBP2a in determining the rod shape of the cell during vegetative growth and spore outgrowth%3B Belongs to the transpeptidase family gene gene1685 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01686 S100027_01687 S100027_01687 kinA kinA 1616644 1618455 + Histidine kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Phosphoprotein%3B Repeat%3B Sporulation%3B Transferase%3B Two-component regulatory system%3B Phosphorylates the sporulation-regulatory proteins spo0A and spo0F. It also autophosphorylates in the presence of ATP. Contains 1 histidine kinase domain%3B Contains 2 PAC (PAS-associated C-terminal) domains%3B Contains 3 PAS (PER-ARNT-SIM) domains%3B KEGG: bli:BL03576 two-component system%2C sporulation sensor kinase A gene gene1686 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01687 S100027_01688 S100027_01688 patA patA 1618487 1619656 - Putative N-acetyl-LL-diaminopimelate aminotransferase Amino-acid biosynthesis%3B Aminotransferase%3B Cytoplasm%3B Diaminopimelate biosynthesis%3B Lysine biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B May catalyze the conversion of L-2-acetamido-6- oxopimelate to N-acetyl-LL-2%2C6-diaminopimelate%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bli:BL03647 aminotransferase%3B Transaminases gene gene1687 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01688 S100027_01689 S100027_01689 S100027_01689 1619848 1620006 - hypothetical protein gene gene1688 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01689 S100027_01690 S100027_01690 S100027_01690 1620178 1620702 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1689 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01690 S100027_01691 S100027_01691 S100027_01691 1620799 1622118 + putative MFS-type transporter YxiO Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene1690 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01691 S100027_01692 S100027_01692 S100027_01692 1622192 1623109 + Chemotaxis protein CheV Chemotaxis%3B Phosphoprotein%3B Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. Chemotaxis involves both a phosphorylation-dependent excitation and a methylation-dependent adaptation. CheV and CheW are involved in the coupling of the methyl-accepting chemoreceptors to the central two-component kinase Che%3B they are both necessary for efficient chemotaxis. Moreover%2C CheA-dependent phosphorylation of CheV is required for adaptation to attractants during B. subtilis chemotaxis%3B Contains 1 cheW-like domain%3B Contains 1 response regulatory domain gene gene1691 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01692 S100027_01693 S100027_01693 S100027_01693 1623141 1623602 - uncharacterized protein gene gene1692 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01693 S100027_01694 S100027_01694 S100027_01694 1623744 1625045 - dTMP kinase Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily%3B KEGG: abai:IMCC26256_11234 dTMP kinase gene gene1693 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01694 S100027_01695 S100027_01695 S100027_01695 1625134 1625631 - Putative L%2CD-transpeptidase YkuD Cell shape%3B Cell wall biogenesis/degradation%3B Glycosyltransferase%3B Hydrolase%3B Peptidoglycan synthesis%3B Sporulation%3B Transferase%3B Probable enzyme that may play an important role in cell wall biology%3B Belongs to the YkuD family%3B Contains 1 LysM repeat gene gene1694 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01695 S100027_01696 S100027_01696 S100027_01696 1625811 1626668 - putative metallophosphoesterase YkuE Hydrolase%3B Metal-binding%3B Signal%3B Belongs to the metallophosphoesterase superfamily gene gene1695 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01696 S100027_01697 S100027_01697 butA butA 1626814 1627578 + Cyclopentanol dehydrogenase NAD%3B Oxidoreductase%3B Reduces cyclopentanol to cyclopentanone. The enzyme also shows considerable activity toward cyclohexanol (By similarity)%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: ecy:ECSE_P3-0048 meso-butanediol dehydrogenase / (S%2CS)-butanediol dehydrogenase / diacetyl reductase%3B With NAD(+) or NADP(+) as acceptor gene gene1696 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01697 S100027_01698 S100027_01698 S100027_01698 1627646 1628866 + Protein-glutamate O-methyltransferase Contains 1 EAL domain%3B KEGG: mah:MEALZ_1025 two-component system%2C chemotaxis family%2C CheB/CheR fusion protein gene gene1697 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01698 S100027_01699 S100027_01699 S100027_01699 1628977 1629603 + hypothetical protein gene gene1698 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01699 S100027_01700 S100027_01700 S100027_01700 1630060 1630302 + uncharacterized protein Signal. gene gene1699 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01700 S100027_01701 S100027_01701 S100027_01701 1630314 1630463 + hypothetical protein gene gene1700 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01701 S100027_01702 S100027_01702 S100027_01702 1630521 1631039 + uncharacterized protein gene gene1701 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01702 S100027_01703 S100027_01703 S100027_01703 1631178 1631357 + uncharacterized protein gene gene1702 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01703 S100027_01704 S100027_01704 S100027_01704 1631538 1631981 + CBS domain-containing protein YkuL CBS domain%3B Contains 1 CBS domain gene gene1703 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01704 S100027_01705 S100027_01705 S100027_01705 1632124 1632999 + putative HTH-type transcriptional regulator YkuM DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH lysR-type DNA-binding domain gene gene1704 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01705 S100027_01706 S100027_01706 S100027_01706 1633131 1633610 + putative flavodoxin-1 Electron transport%3B Flavoprotein%3B FMN%3B Transport%3B Low-potential electron donor to a number of redox enzymes%3B Belongs to the flavodoxin family%3B Contains 1 flavodoxin-like domain gene gene1705 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01706 S100027_01707 S100027_01707 S100027_01707 1633600 1634493 + uncharacterized protein gene gene1706 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01707 S100027_01708 S100027_01708 S100027_01708 1634523 1634975 + putative flavodoxin-2 Electron transport%3B Flavoprotein%3B FMN%3B Transport%3B Low-potential electron donor to a number of redox enzymes%3B Belongs to the flavodoxin family%3B Contains 1 flavodoxin-like domain gene gene1707 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01708 S100027_01709 S100027_01709 dapH dapH 1635081 1635791 + Tetrahydrodipicolinate N-acetyltransferase Acyltransferase%3B Amino-acid biosynthesis%3B Diaminopimelate biosynthesis%3B Lysine biosynthesis%3B Repeat%3B Transferase%3B Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate%3B Belongs to the transferase hexapeptide repeat family. DapH subfamily%3B KEGG: bsu:BSU14180 tetrahydrodipicolinate N-acetyltransferase gene gene1708 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01709 S100027_01710 S100027_01710 S100027_01710 1635861 1636985 + N-acetyldiaminopimelate deacetylase Amino-acid biosynthesis%3B Diaminopimelate biosynthesis%3B Hydrolase%3B Lysine biosynthesis%3B Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate%3B Belongs to the peptidase M20A family. N- acetyldiaminopimelate deacetylase subfamily%3B KEGG: bli:BL05143 N-acetyldiaminopimelate deacetylase gene gene1709 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01710 S100027_01711 S100027_01711 S100027_01711 1637048 1637293 + UPF0180 protein Belongs to the UPF0180 family gene gene1710 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01711 S100027_01712 S100027_01712 prdX prdX 1637588 1638130 + Peroxiredoxin Belongs to the thioredoxin family%3B Contains 1 thioredoxin domain%3B KEGG: bfr:BF2266 peroxiredoxin (alkyl hydroperoxide reductase subunit C) gene gene1711 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01712 S100027_01713 S100027_01713 S100027_01713 1638212 1638670 + Thiol-disulfide oxidoreductase YkuV Cytoplasm%3B Disulfide bond%3B Electron transport%3B Oxidoreductase%3B Redox-active center%3B Transport%3B Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Contains 1 thioredoxin domain gene gene1712 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01713 S100027_01714 S100027_01714 S100027_01714 1639218 1639808 + Repressor rok Coiled coil%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation. gene gene1713 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01714 S100027_01715 S100027_01715 S100027_01715 1639955 1640911 - Sporulation protein cse15 Coiled coil%3B Sporulation. gene gene1714 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01715 S100027_01716 S100027_01716 S100027_01716 1641064 1641651 + Molybdenum cofactor guanylyltransferase Cytoplasm%3B GTP-binding%3B Magnesium%3B Metal-binding%3B Molybdenum cofactor biosynthesis%3B Nucleotide-binding%3B Transferase%3B Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor%3B Belongs to the MobA family%3B KEGG: bli:BL00558 molybdopterin-guanine dinucleotide biosynthesis protein A gene gene1715 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01716 S100027_01717 S100027_01717 S100027_01717 1641688 1642770 + Molybdopterin-synthase adenylyltransferase ATP-binding%3B Metal-binding%3B Molybdenum cofactor biosynthesis%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase%3B Zinc%3B Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein MoaD%3B Belongs to the HesA/MoeB/ThiF family gene gene1716 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01717 S100027_01718 S100027_01718 moeA moeA 1642790 1644082 + Molybdopterin molybdotransferase Magnesium%3B Metal-binding%3B Molybdenum%3B Molybdenum cofactor biosynthesis%3B Transferase%3B Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP%3B Belongs to the MoeA family%3B KEGG: bsu:BSU14280 molybdopterin molybdotransferase gene gene1717 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01718 S100027_01719 S100027_01719 S100027_01719 1644049 1644576 + putative molybdopterin-guanine dinucleotide biosynthesis adapter protein GTP-binding%3B Molybdenum cofactor biosynthesis%3B Nucleotide-binding%3B GTP-binding protein that is not required for the biosynthesis of Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor%2C and not necessary for the formation of active molybdoenzymes using this form of molybdenum cofactor. May act as an adapter protein to achieve the efficient biosynthesis and utilization of MGD. Displays a weak intrinsic GTPase activity (By similarity)%3B Belongs to the MobB family gene gene1718 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01719 S100027_01720 S100027_01720 moaE moaE 1644555 1645049 + Molybdopterin synthase Molybdenum cofactor biosynthesis%3B Transferase%3B Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD (By similarity)%3B Belongs to the MoaE family%3B KEGG: bli:BL00554 molybdopterin synthase catalytic subunit gene gene1719 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01720 S100027_01721 S100027_01721 S100027_01721 1645046 1645279 + Molybdopterin synthase sulfur carrier subunit Molybdenum cofactor biosynthesis%3B Nucleotide-binding%3B Phosphoprotein%3B Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin%3B Belongs to the MoaD family gene gene1720 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01721 S100027_01722 S100027_01722 S100027_01722 1645309 1645686 - hypothetical protein gene gene1721 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01722 S100027_01723 S100027_01723 S100027_01723 1645953 1647710 + Lipid A export ATP-binding/permease protein MsbA ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Lipid transport%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation%3B Belongs to the ABC transporter superfamily. Lipid exporter (TC 3. A. 1. 106) family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene1722 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01723 S100027_01724 S100027_01724 S100027_01724 1647723 1649543 + putative ABC transporter ATP-binding protein YknV ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene1723 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01724 S100027_01725 S100027_01725 S100027_01725 1649663 1650343 + Membrane protein YknW Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Part of an unusual four-component transporter%2C which is required for protection against the killing factor SdpC (sporulation-delaying protein). Has a role in the assembly of the YknXYZ complex gene gene1724 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01725 S100027_01726 S100027_01726 S100027_01726 1650344 1651480 + Putative efflux system component YknX Cell membrane%3B Coiled coil%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Part of an unusual four-component transporter%2C which is required for protection against the killing factor SdpC (sporulation-delaying protein)%3B Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene1725 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01726 S100027_01727 S100027_01727 macB macB 1651477 1652169 + Macrolide export ATP-binding/permease protein MacB Antibiotic resistance%3B ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD)%2C which form a pore in the inner membrane%2C and an ATP-binding domain (NBD)%2C which is responsible for energy generation. Confers resistance against macrolides%3B Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3. A. 1. 122) family%3B Contains 1 ABC transporter domain%3B KEGG: efe:EFER_1027 macrolide transport system ATP-binding/permease protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene1726 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01727 S100027_01728 S100027_01728 S100027_01728 1652166 1653359 + putative ABC transporter permease YknZ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of an unusual four-component transporter%2C which is required for protection against the killing factor SdpC (sporulation-delaying protein)%3B Belongs to the ABC-4 integral membrane protein family gene gene1727 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01728 S100027_01729 S100027_01729 S100027_01729 1653990 1654745 + putative HTH-type transcriptional regulator FruR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH deoR-type DNA-binding domain gene gene1728 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01729 S100027_01730 S100027_01730 pfkB pfkB 1654742 1655653 + 6-phosphofructokinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the carbohydrate kinase PfkB family%3B KEGG: sty:STY3436 6-phosphofructokinase 2 gene gene1729 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01730 S100027_01731 S100027_01731 fruB fruB 1655667 1657562 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Membrane%3B Phosphoprotein%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport (By similarity)%3B Contains 1 PTS EIIA type-2 domain%3B Contains 1 PTS EIIB type-2 domain%3B Contains 1 PTS EIIC type-2 domain%3B KEGG: ron:TE10_11530 PTS system%2C fructose-specific IIA component gene gene1730 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01731 S100027_01732 S100027_01732 S100027_01732 1657729 1658289 + Signal peptidase I Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Belongs to the peptidase S26 family%3B KEGG: bli:BL01607 signal peptidase I gene gene1731 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01732 S100027_01733 S100027_01733 S100027_01733 1658335 1658604 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1732 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01733 S100027_01734 S100027_01734 S100027_01734 1658617 1658859 - hypothetical protein gene gene1733 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01734 S100027_01735 S100027_01735 S100027_01735 1659032 1660651 + Arabinose import ATP-binding protein AraG ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Repeat%3B Sugar transport%3B Transport%3B Part of the ABC transporter complex AraFGH involved in arabinose import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Arabinose importer (TC 3. A. 1. 2. 2) family%3B Contains 2 ABC transporter domains gene gene1734 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01735 S100027_01736 S100027_01736 S100027_01736 1660708 1661082 + hypothetical protein gene gene1735 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01736 S100027_01737 S100027_01737 S100027_01737 1661220 1662452 - Aminopeptidase AmpS Aminopeptidase%3B Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Zinc%3B Metal-dependent exopeptidase%3B Belongs to the peptidase M29 family%3B KEGG: bsu:BSU14450 aminopeptidase%3B Aminopeptidases gene gene1736 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01737 S100027_01738 S100027_01738 S100027_01738 1662543 1662674 - uncharacterized protein Signal. gene gene1737 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01738 S100027_01739 S100027_01739 S100027_01739 1662748 1663755 - Protein MreBH Belongs to the FtsA/MreB family gene gene1738 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01739 S100027_01740 S100027_01740 S100027_01740 1664062 1664349 + Putative transition state regulator Abh DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 SpoVT-AbrB domain%3B To B. subtilis AbrB and SpoVT gene gene1739 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01740 S100027_01741 S100027_01741 kinC kinC 1664517 1665854 + Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Sporulation%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Phosphorylates the sporulation-regulatory protein spo0A. Contains 1 histidine kinase domain%3B Contains 1 PAC (PAS-associated C-terminal) domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bsu:BSU14490 two-component system%2C sporulation sensor kinase C gene gene1740 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01741 S100027_01742 S100027_01742 S100027_01742 1665919 1666581 + Ktr system potassium uptake protein Cell membrane%3B Ion transport%3B Membrane%3B NAD%3B Potassium%3B Potassium transport%3B Transport%3B Catalytic subunit of the KtrCD potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress%3B Belongs to the KtrA potassium transport family%3B Contains 1 RCK C-terminal domain%3B Contains 1 RCK N-terminal domain gene gene1741 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01742 S100027_01743 S100027_01743 S100027_01743 1666721 1668430 + Adenine deaminase Hydrolase%3B Manganese%3B Belongs to the adenine deaminase family%3B KEGG: bli:BL01613 adenine deaminase gene gene1742 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01743 S100027_01744 S100027_01744 S100027_01744 1668483 1670150 - Ribonuclease J1 Calcium%3B Cytoplasm%3B Endonuclease%3B Exonuclease%3B Hydrolase%3B Metal-binding%3B mRNA processing%3B Nuclease%3B RNA-binding%3B rRNA processing%3B Zinc%3B An RNase that has endonuclease and 5'-3' exonuclease activity%2C playing a role in both rRNA and mRNA stability and degradation. Endonuclease activity can cleave within 4 nucleotides of the 5'-end of a triphosphorylated RNA. Endonuclease digestion by the RNase J1/J2 complex occurs at a different site and in some cases more efficiently than J1 or J2 alone. The exonuclease activity of the J1/J2 complex is highly processive on substrates longer than 5 nucleotides%2C on shorter substrates is distributive. Preferentially cleaves ssRNA%2C possibly in AU-rich regions. The 5'- exonuclease activity acts on 5'-hydroxyl and 5'-monophosphate but not 5'-triphosphate end%3B it can digest through stem-loop structures if they are not too stable. Required for maturation of 16S rRNA. Acts preferentially on 16S rRNA precursors after association of the 30S and 50S ribosomal subunits. Plays a role in the secondary pathway of 23S rRNA 5' end maturation. Probably also participates in processing of pre-scRNA (the precursor of the signal recognition particle RNA)%3B Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily%3B KEGG: bsu:BSU14530 ribonuclease J%3B Acting on ester bonds gene gene1743 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01744 S100027_01745 S100027_01745 S100027_01745 1670155 1670364 - UPF0356 protein Belongs to the UPF0356 family gene gene1744 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01745 S100027_01746 S100027_01746 S100027_01746 1670764 1671540 + Putative phosphatase YkrA Hydrolase%3B Magnesium%3B Metal-binding%3B Belongs to the HAD-like hydrolase superfamily. Cof family gene gene1745 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01746 S100027_01747 S100027_01747 S100027_01747 1671656 1673086 + hypothetical protein gene gene1746 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01747 S100027_01748 S100027_01748 S100027_01748 1673120 1673677 - Peptide deformylase Hydrolase%3B Iron%3B Metal-binding%3B Protein biosynthesis%3B Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. Belongs to the polypeptide deformylase family%3B KEGG: bld:BLi01671 peptide deformylase gene gene1747 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01748 S100027_01749 S100027_01749 S100027_01749 1673796 1673927 - UPF0752 membrane protein YkzV Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0752 family gene gene1748 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01749 S100027_01750 S100027_01750 S100027_01750 1674184 1674852 + putative lipoprotein YkyA Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal. gene gene1749 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01750 S100027_01751 S100027_01751 S100027_01751 1675252 1676367 + Pyruvate dehydrogenase (acetyl-transferring) Glycolysis%3B Oxidoreductase%3B Pyruvate%3B Thiamine pyrophosphate%3B KEGG: bsu:BSU14580 pyruvate dehydrogenase E1 component alpha subunit gene gene1750 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01751 S100027_01752 S100027_01752 S100027_01752 1676371 1677348 + Pyruvate dehydrogenase (acetyl-transferring) Glycolysis%3B Oxidoreductase%3B Pyruvate%3B Thiamine pyrophosphate%3B KEGG: rhd:R2APBS1_0530 pyruvate dehydrogenase E1 component beta subunit gene gene1751 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01752 S100027_01753 S100027_01753 dlaT dlaT 1677511 1678803 + Dihydrolipoyllysine-residue acetyltransferase Acyltransferase%3B Glycolysis%3B Lipoyl%3B Transferase%3B The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1)%2C dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The B. subtilis PDH complex possesses also branched-chain 2-oxoacid dehydrogenase (BCDH) activity. Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: rbu:PG1C_10405 pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) gene gene1752 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01753 S100027_01754 S100027_01754 S100027_01754 1678808 1680220 + Dihydrolipoyl dehydrogenase Cytoplasm%3B Disulfide bond%3B FAD%3B Flavoprotein%3B Glycolysis%3B NAD%3B Oxidoreductase%3B Redox-active center%3B Catalyzes the oxidation of dihydrolipoamide to lipoamide. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: bsu:BSU14610 dihydrolipoamide dehydrogenase gene gene1753 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01754 S100027_01755 S100027_01755 S100027_01755 1680251 1680409 + hypothetical protein gene gene1754 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01755 S100027_01756 S100027_01756 S100027_01756 1680339 1680716 - Pal-related lipoprotein Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal. gene gene1755 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01756 S100027_01757 S100027_01757 S100027_01757 1681092 1681211 + uncharacterized protein gene gene1756 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01757 S100027_01758 S100027_01758 speA speA 1681256 1682746 - Arginine decarboxylase Cytoplasm%3B Decarboxylase%3B Lyase%3B Polyamine biosynthesis%3B Putrescine biosynthesis%3B Pyridoxal phosphate%3B Spermidine biosynthesis%3B Catalyzes the formation of agmatine from arginine. Belongs to the Orn/Lys/Arg decarboxylase class-I family%3B KEGG: bli:BL01634 arginine decarboxylase gene gene1757 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01758 S100027_01759 S100027_01759 S100027_01759 1682984 1683259 + UPF0223 protein Belongs to the UPF0223 family gene gene1758 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01759 S100027_01760 S100027_01760 S100027_01760 1683311 1683946 - UPF0637 protein Belongs to the UPF0637 family gene gene1759 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01760 S100027_01761 S100027_01761 S100027_01761 1684191 1684379 + uncharacterized protein Coiled coil. gene gene1760 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01761 S100027_01762 S100027_01762 impA impA 1684521 1685315 + Inositol-phosphate phosphatase Hydrolase%3B Magnesium%3B Metal-binding%3B Belongs to the inositol monophosphatase family%3B KEGG: bli:BL05151 myo-inositol-1(or 4)-monophosphatase gene gene1761 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01762 S100027_01763 S100027_01763 S100027_01763 1685380 1685775 + uncharacterized protein Contains 1 N-acetyltransferase domain gene gene1762 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01763 S100027_01764 S100027_01764 S100027_01764 1685883 1687808 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B overlaps another CDS with the same product name gene gene1763 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01764 S100027_01765 S100027_01765 S100027_01765 1687798 1688073 + uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix%3B overlaps another CDS with the same product name gene gene1764 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01765 S100027_01766 S100027_01766 S100027_01766 1688074 1688589 + RNA polymerase sigma factor YlaC DNA-binding%3B Sigma factor%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor contributes to oxidative stress resistance%3B Belongs to the sigma-70 factor family. ECF subfamily gene gene1765 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01766 S100027_01767 S100027_01767 S100027_01767 1688594 1688890 + Anti-sigma-YlaC factor YlaD Cell membrane%3B Membrane%3B Metal-binding%3B Transmembrane%3B Transmembrane helix%3B Zinc%3B Anti-sigma factor for YlaC%3B Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily gene gene1766 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01767 S100027_01768 S100027_01768 S100027_01768 1688964 1689152 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1767 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01768 S100027_01769 S100027_01769 S100027_01769 1689314 1691152 + GTP-binding protein TypA/BipA like protein GTP-binding%3B Nucleotide-binding%3B Not know%3B probably interacts with the ribosomes in a GTP dependent manner%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. TypA subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene1768 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01769 S100027_01770 S100027_01770 S100027_01770 1691210 1691530 + putative membrane protein YlaH Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1769 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01770 S100027_01771 S100027_01771 S100027_01771 1691552 1692058 - putative HTH-type transcriptional regulator YhjH Cytoplasm%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH marR-type DNA-binding domain gene gene1770 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01771 S100027_01772 S100027_01772 mhpA mhpA 1692147 1693628 - 3-(3-hydroxy-phenyl)propanoic acid hydroxylase Antibiotic biosynthesis%3B FAD%3B Flavoprotein%3B NADP%3B Oxidoreductase%3B Catalyzes hydroxylation of the anthracycline structure at position C-6 during the biosynthesis of oxytetracyline%3B Belongs to the PheA/TfdB FAD monooxygenase family%3B KEGG: mxa:MXAN_1594 3-(3-hydroxy-phenyl)propionate hydroxylase gene gene1771 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01772 S100027_01773 S100027_01773 S100027_01773 1693767 1693973 - uncharacterized protein gene gene1772 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01773 S100027_01774 S100027_01774 S100027_01774 1694094 1694708 - putative lipoprotein YlaJ Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal. gene gene1773 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01774 S100027_01775 S100027_01775 S100027_01775 1694864 1696192 + uncharacterized protein ATP-binding%3B Nucleotide-binding%3B In the C-terminal sectio%3B belongs to the PhoH family%3B Contains 1 PINc domain gene gene1774 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01775 S100027_01776 S100027_01776 S100027_01776 1696336 1696818 - uncharacterized protein gene gene1775 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01776 S100027_01777 S100027_01777 S100027_01777 1696937 1697866 + Glutaminase Hydrolase%3B Belongs to the glutaminase family%3B KEGG: bsr:I33_1665 glutaminase gene gene1776 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01777 S100027_01778 S100027_01778 S100027_01778 1697999 1698280 + UPF0358 protein Belongs to the UPF0358 family gene gene1777 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01778 S100027_01779 S100027_01779 S100027_01779 1698611 1699822 + Putative lipid II flippase FtsW Cell cycle%3B Cell division%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Peptidoglycan synthesis%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Essential cell division protein (Probable). Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane (By similarity)%3B Belongs to the SEDS family. FtsW subfamily gene gene1778 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01779 S100027_01780 S100027_01780 S100027_01780 1699901 1703344 + Pyruvate carboxylase ATP-binding%3B Biotin%3B Ligase%3B Metal-binding%3B Multifunctional enzyme%3B Nucleotide-binding%3B Catalyzes a 2-step reaction%2C involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second%2C leading to oxaloacetate production. Fulfills an anaplerotic function in B. subtilis as it is necessary for growth on glucose%2C but is not required for sporulation%3B Contains 1 ATP-grasp domain%3B Contains 1 biotin carboxylation domain%3B Contains 1 biotinyl-binding domain%3B Contains 1 carboxyltransferase domain%3B KEGG: bsu:BSU14860 pyruvate carboxylase gene gene1779 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01780 S100027_01781 S100027_01781 S100027_01781 1703426 1704334 - Heme A synthase Cell membrane%3B Heme biosynthesis%3B Membrane%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group%3B Belongs to the COX15/CtaA family. Type 1 subfamily gene gene1780 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01781 S100027_01782 S100027_01782 cyoE cyoE 1704736 1705662 + Protoheme IX farnesyltransferase Cell membrane%3B Heme biosynthesis%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group%3B Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily%3B KEGG: bli:BL02979 protoheme IX farnesyltransferase%3B Transferring alkyl or aryl groups%2C other than methyl groups gene gene1781 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01782 S100027_01783 S100027_01783 coxB coxB 1705940 1707007 + Cytochrome-c oxidase Cell membrane%3B Copper%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Respiratory chain%3B Signal%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). Belongs to the cytochrome c oxidase subunit 2 family%3B Contains 1 cytochrome c domain%3B KEGG: bli:BL02980 cytochrome c oxidase subunit II gene gene1782 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01783 S100027_01784 S100027_01784 coxA coxA 1707040 1708908 + Cytochrome-c oxidase Cell membrane%3B Copper%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Respiratory chain%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme a of subunit 1 to the bimetallic center formed by heme a3 and copper B. This cytochrome c oxidase shows proton pump activity across the membrane in addition to the electron transfer. Belongs to the heme-copper respiratory oxidase family%3B KEGG: bli:BL02981 cytochrome c oxidase subunit I%3B overlaps another CDS with the same product name gene gene1783 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01784 S100027_01785 S100027_01785 coxC coxC 1708908 1709531 + Cytochrome-c oxidase Cell membrane%3B Membrane%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Belongs to the cytochrome c oxidase subunit 3 family%3B KEGG: bli:BL02982 cytochrome c oxidase subunit III%3B overlaps another CDS with the same product name gene gene1784 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01785 S100027_01786 S100027_01786 coxD coxD 1709534 1709863 + Cytochrome-c oxidase Cell membrane%3B Membrane%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Belongs to the cytochrome c oxidase bacterial subunit 4 family%3B KEGG: bli:BL02983 cytochrome c oxidase subunit IV gene gene1785 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01786 S100027_01787 S100027_01787 S100027_01787 1709894 1710796 + Protein CtaG Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1786 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01787 S100027_01788 S100027_01788 S100027_01788 1710853 1711212 - uncharacterized protein gene gene1787 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01788 S100027_01789 S100027_01789 S100027_01789 1711380 1711826 + uncharacterized protein CBS domain%3B Repeat%3B Contains 2 CBS domains gene gene1788 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01789 S100027_01790 S100027_01790 S100027_01790 1711967 1713010 + putative membrane protein YlbC Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Contains 1 SCP domain gene gene1789 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01790 S100027_01791 S100027_01791 S100027_01791 1713164 1713559 + uncharacterized protein gene gene1790 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01791 S100027_01792 S100027_01792 S100027_01792 1713574 1713813 + uncharacterized protein gene gene1791 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01792 S100027_01793 S100027_01793 S100027_01793 1713891 1714022 + hypothetical protein gene gene1792 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01793 S100027_01794 S100027_01794 S100027_01794 1714092 1714541 + Regulatory protein YlbF Competence%3B Cytoplasm%3B Sporulation%3B Regulates sporulation prior to stage II. Positively controls the competence regulator ComK at a post-transcriptional level. May modulate the translation%2C stability or activity of ComS. May work together with YmcA to regulate community development gene gene1793 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01794 S100027_01795 S100027_01795 S100027_01795 1714541 1714885 + UPF0298 protein Cytoplasm%3B Belongs to the UPF0298 family gene gene1794 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01795 S100027_01796 S100027_01796 S100027_01796 1714995 1715129 + hypothetical protein gene gene1795 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01796 S100027_01797 S100027_01797 rsmD rsmD 1715184 1715744 + 16S rRNA (guanine(966)-N(2))-methyltransferase Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B May catalyze the S-adenosyl-L-methionine-dependent methylation of a specific base in rRNA%3B Belongs to the methyltransferase superfamily. RsmD family%3B KEGG: vsp:VS_3023 16S rRNA (guanine966-N2)-methyltransferase gene gene1796 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01797 S100027_01798 S100027_01798 coaD coaD 1715737 1716231 + Pantetheine-phosphate adenylyltransferase ATP-binding%3B Coenzyme A biosynthesis%3B Cytoplasm%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase%3B Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine%2C yielding dephospho-CoA (dPCoA) and pyrophosphate%3B Belongs to the bacterial CoaD family%3B KEGG: bsu:BSU15020 pantetheine-phosphate adenylyltransferase gene gene1797 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01798 S100027_01799 S100027_01799 S100027_01799 1716240 1717460 - Sporulation integral membrane protein YlbJ Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Required for spore cortex formation gene gene1798 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01799 S100027_01800 S100027_01800 S100027_01800 1717784 1718806 + uncharacterized protein Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Serine protease%3B Transmembrane%3B Transmembrane helix%3B Contains 1 PDZ (DHR) domain gene gene1799 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01800 S100027_01801 S100027_01801 S100027_01801 1718823 1720073 - UPF0348 protein Belongs to the UPF0348 family gene gene1800 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01801 S100027_01802 S100027_01802 S100027_01802 1720291 1720806 + uncharacterized protein gene gene1801 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01802 S100027_01803 S100027_01803 S100027_01803 1720830 1721003 + 50S ribosomal protein L32-2 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L32P family gene gene1802 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01803 S100027_01804 S100027_01804 S100027_01804 1721158 1721757 + uncharacterized protein DNA-binding%3B Contains 1 HTH myb-type DNA-binding domain gene gene1803 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01804 S100027_01805 S100027_01805 S100027_01805 1721800 1722279 - putative N-acetyltransferase Acyltransferase%3B Transferase%3B Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK3680 null%3B Transferring groups other than amino-acyl groups gene gene1804 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01805 S100027_01806 S100027_01806 panE panE 1722462 1723343 + 2-dehydropantoate 2-reductase Cytoplasm%3B NADP%3B Oxidoreductase%3B Pantothenate biosynthesis%3B Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid%3B Belongs to the ketopantoate reductase family%3B KEGG: bsu:BSU15110 2-dehydropantoate 2-reductase gene gene1805 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01806 S100027_01807 S100027_01807 S100027_01807 1723428 1725044 + Putative cysteine ligase BshC Coiled coil%3B Ligase%3B Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway%2C the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH%3B Belongs to the BshC family gene gene1806 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01807 S100027_01808 S100027_01808 S100027_01808 1725155 1725601 + Transcriptional regulator MraZ Cytoplasm%3B DNA-binding%3B Repeat%3B Transcription%3B Transcription regulation%3B Belongs to the MraZ family%3B Contains 2 SpoVT-AbrB domains gene gene1807 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01808 S100027_01809 S100027_01809 mraW mraW 1725601 1726605 + 16S rRNA (cytosine(1402)-N(4))-methyltransferase Cytoplasm%3B Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA%3B Belongs to the methyltransferase superfamily. RsmH family%3B KEGG: pca:Pcar_2210 16S rRNA (cytosine1402-N4)-methyltransferase gene gene1808 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01809 S100027_01810 S100027_01810 S100027_01810 1726637 1726990 + Cell division protein FtsL Cell cycle%3B Cell division%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Essential cell division protein%3B Belongs to the FtsL family gene gene1809 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01810 S100027_01811 S100027_01811 S100027_01811 1726997 1729132 + Penicillin-binding protein 2B Antibiotic resistance%3B Cell cycle%3B Cell division%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Peptidoglycan synthesis%3B Repeat%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis. PBP-2B is required for vegetative cell division and sporulation septation. Beta-lactamase inactivates the PBPs by acylating an essential serine residue in the active site of these proteins%2C thereby interrupting normal cell wall synthesis. Belongs to the transpeptidase family%3B Contains 2 PASTA domains gene gene1810 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01811 S100027_01812 S100027_01812 S100027_01812 1729275 1731209 + Stage V sporulation protein D Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Peptidoglycan synthesis%3B Sporulation%3B Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex%2C which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell. Belongs to the transpeptidase family%3B Contains 1 PASTA domain gene gene1811 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01812 S100027_01813 S100027_01813 S100027_01813 1731241 1731381 + hypothetical protein gene gene1812 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01813 S100027_01814 S100027_01814 murE murE 1731405 1732871 + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2%2C6-diaminopimelate ligase ATP-binding%3B Cell cycle%3B Cell division%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Ligase%3B Magnesium%3B Nucleotide-binding%3B Peptidoglycan synthesis%3B Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan%3B Belongs to the MurCDEF family. MurE subfamily%3B KEGG: bsu:BSU15180 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2%2C6-diaminopimelate ligase gene gene1813 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01814 S100027_01815 S100027_01815 mraY mraY 1732999 1733973 + Phospho-N-acetylmuramoyl-pentapeptide-transferase Cell cycle%3B Cell division%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Peptidoglycan synthesis%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan%3B Belongs to the glycosyltransferase 4 family. MraY subfamily%3B KEGG: bsu:BSU15190 phospho-N-acetylmuramoyl-pentapeptide-transferase gene gene1814 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01815 S100027_01816 S100027_01816 murD murD 1733974 1735329 + UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase ATP-binding%3B Cell cycle%3B Cell division%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Peptidoglycan synthesis%3B Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)%3B Belongs to the MurCDEF family%3B KEGG: bli:BL02241 UDP-N-acetylmuramoylalanine--D-glutamate ligase gene gene1815 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01816 S100027_01817 S100027_01817 S100027_01817 1735412 1736482 + Putative lipid II flippase FtsW Cell cycle%3B Cell division%3B Cell inner membrane%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Peptidoglycan synthesis%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Essential cell division protein. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane%3B Belongs to the SEDS family. FtsW subfamily gene gene1816 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01817 S100027_01818 S100027_01818 murG murG 1736554 1737654 + Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase Cell cycle%3B Cell division%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Glycosyltransferase%3B Membrane%3B Peptidoglycan synthesis%3B Transferase%3B Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)%3B Belongs to the glycosyltransferase 28 family. MurG subfamily%3B KEGG: gsu:GSU3069 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase gene gene1817 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01818 S100027_01819 S100027_01819 murB murB 1737683 1738594 + UDP-N-acetylmuramate dehydrogenase Cell cycle%3B Cell division%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B FAD%3B Flavoprotein%3B NADP%3B Oxidoreductase%3B Peptidoglycan synthesis%3B Cell wall formation%3B Belongs to the MurB family%3B Contains 1 FAD-binding PCMH-type domain%3B KEGG: bsu:BSU15230 UDP-N-acetylmuramate dehydrogenase gene gene1818 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01819 S100027_01820 S100027_01820 S100027_01820 1738800 1739588 + Cell division protein DivIB Cell cycle%3B Cell division%3B Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex. Plays an essential role in division at high temperatures%2C maybe by protecting FtsL from degradation or by promoting formation of the FtsL-DivIC complex. May modulate the transpeptidase activity of PBP-2B. Also required for efficient sporulation at all temperatures. Could be directly involved in the engulfment process or be required to form a sporulation septum competent for engulfment. Influences the Spo0J/Soj system of chromosome segregation%3B Belongs to the FtsQ/DivIB family. DivIB subfamily%3B Contains 1 POTRA domain gene gene1819 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01820 S100027_01821 S100027_01821 S100027_01821 1739585 1740277 + UPF0749 protein YlxW Cell cycle%3B Cell division%3B Coiled coil%3B Signal%3B Sporulation%3B May be involved in cell division and sporulation%3B Belongs to the UPF0749 family gene gene1820 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01821 S100027_01822 S100027_01822 S100027_01822 1740303 1741028 + UPF0749 protein YlxX Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0749 family gene gene1821 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01822 S100027_01823 S100027_01823 S100027_01823 1741028 1741381 + Small basic protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the sbp family gene gene1822 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01823 S100027_01824 S100027_01824 S100027_01824 1741565 1742863 + Cell division protein FtsA Cell cycle%3B Cell division%3B Cell membrane%3B Cell shape%3B Membrane%3B Sporulation%3B Cell division protein that is required for the assembly of the Z ring (PubMed:16159787). May serve as a membrane anchor for the Z ring (By similarity). Binds and hydrolyzes ATP (PubMed:11298280). Also involved in sporulation (Probable)%3B Belongs to the FtsA/MreB family gene gene1823 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01824 S100027_01825 S100027_01825 S100027_01825 1742898 1744031 + Cell division protein FtsZ Cell cycle%3B Cell division%3B Cytoplasm%3B GTP-binding%3B Nucleotide-binding%3B Septation%3B Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity%3B Belongs to the FtsZ family gene gene1824 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01825 S100027_01826 S100027_01826 S100027_01826 1744411 1745919 + Bacillopeptidase Hydrolase%3B Protease%3B Secreted%3B Serine protease%3B Signal%3B Zymogen%3B Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: blh:BaLi_c17820 bacillopeptidase F%3B Serine endopeptidases gene gene1825 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01826 S100027_01827 S100027_01827 S100027_01827 1745959 1747389 - hypothetical protein gene gene1826 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01827 S100027_01828 S100027_01828 S100027_01828 1747671 1749554 + Bacillopeptidase Hydrolase%3B Protease%3B Secreted%3B Serine protease%3B Signal%3B Zymogen%3B Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bli:BL02253 bacillopeptidase F%3B Serine endopeptidases%3B overlaps another CDS with the same product name gene gene1827 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01828 S100027_01829 S100027_01829 S100027_01829 1749551 1751968 + Bacillopeptidase Hydrolase%3B Protease%3B Secreted%3B Serine protease%3B Signal%3B Zymogen%3B Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bli:BL02253 bacillopeptidase F%3B Serine endopeptidases%3B overlaps another CDS with the same product name gene gene1828 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01829 S100027_01830 S100027_01830 S100027_01830 1752070 1753080 + Sporulation sigma-E factor-processing peptidase Aspartyl protease%3B Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR (By similarity)%3B Belongs to the peptidase U4 family%3B KEGG: bli:BL02254 stage II sporulation protein GA (sporulation sigma-E factor processing peptidase)%3B Aspartic endopeptidases gene gene1829 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01830 S100027_01831 S100027_01831 S100027_01831 1753140 1753859 + RNA polymerase sigma-E factor DNA-binding%3B Sigma factor%3B Sporulation%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes. Belongs to the sigma-70 factor family gene gene1830 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01831 S100027_01832 S100027_01832 S100027_01832 1753999 1754778 + RNA polymerase sigma-G factor DNA-binding%3B Sigma factor%3B Sporulation%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the forespore. Belongs to the sigma-70 factor family gene gene1831 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01832 S100027_01833 S100027_01833 S100027_01833 1754914 1755603 + Iron-chelate-transporting ATPase ATP-binding%3B Hydrolase%3B Nucleotide-binding%3B Transport%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: fau:Fraau_2706 iron complex transport system ATP-binding protein gene gene1832 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01833 S100027_01834 S100027_01834 S100027_01834 1755978 1756865 + 23S rRNA (guanine(745)-N(1))-methyltransferase Metal-binding%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Zinc%3B Belongs to the methyltransferase superfamily. RlmA family%3B KEGG: blh:BaLi_c17880 23S rRNA (guanine745-N1)-methyltransferase gene gene1833 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01834 S100027_01835 S100027_01835 S100027_01835 1756950 1757183 + uncharacterized protein Belongs to the YlmC/YmxH family gene gene1834 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01835 S100027_01836 S100027_01836 S100027_01836 1757407 1758246 + Laccase domain protein YlmD Belongs to the LACC1 family gene gene1835 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01836 S100027_01837 S100027_01837 S100027_01837 1758254 1758949 + UPF0001 protein YlmE Pyridoxal phosphate%3B Belongs to the UPF0001 family gene gene1836 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01837 S100027_01838 S100027_01838 S100027_01838 1758946 1759398 + Cell division protein SepF Cell cycle%3B Cell division%3B Cytoplasm%3B Septation%3B Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation%2C perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA%3B Belongs to the SepF family gene gene1837 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01838 S100027_01839 S100027_01839 S100027_01839 1759406 1759675 + putative membrane protein YlmG Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the YggT family gene gene1838 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01839 S100027_01840 S100027_01840 S100027_01840 1759811 1760587 + Putative RNA-binding protein YlmH RNA-binding%3B Contains 1 S4 RNA-binding domain gene gene1839 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01840 S100027_01841 S100027_01841 S100027_01841 1760683 1761177 + Septum site-determining protein DivIVA Cell cycle%3B Cell division%3B Coiled coil%3B Cytoplasm%3B Septation%3B Sporulation%3B May act as a pilot protein%2C directing MinCD to the polar septation sites or by inhibiting MinCD at the midcell site of division. Required for polar localization of the chromosome during sporulation%3B Belongs to the DivIVA family gene gene1840 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01841 S100027_01842 S100027_01842 iarS iarS 1761521 1764289 + Isoleucine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B Zinc%3B Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine%2C to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)%3B Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily%3B KEGG: hhe:HH1190 isoleucyl-tRNA synthetase gene gene1841 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01842 S100027_01843 S100027_01843 S100027_01843 1764553 1764918 + uncharacterized protein Metal-binding%3B Zinc%3B Zinc-finger%3B Contains 1 dksA C4-type zinc finger gene gene1842 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01843 S100027_01844 S100027_01844 lspA lspA 1764963 1765502 + Signal peptidase II Aspartyl protease%3B Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Transmembrane%3B Transmembrane helix%3B This protein specifically catalyzes the removal of signal peptides from prolipoproteins%3B Belongs to the peptidase A8 family%3B KEGG: blh:BaLi_c17980 signal peptidase II gene gene1843 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01844 S100027_01845 S100027_01845 S100027_01845 1765504 1766418 + 23S rRNA pseudouridine(1911/1915/1917) synthase Isomerase%3B RNA-binding%3B Belongs to the pseudouridine synthase RluA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: bli:BL02270 23S rRNA pseudouridine1911/1915/1917 synthase gene gene1844 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01845 S100027_01846 S100027_01846 pyrR pyrR 1766596 1767144 + Uracil phosphoribosyltransferase Glycosyltransferase%3B RNA-binding%3B Transcription%3B Transcription regulation%3B Transcription termination%3B Transferase%3B Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator%2C leading to a reduced expression of downstream genes%3B Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant%3B Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily%3B KEGG: bli:BL02271 pyrimidine operon attenuation protein / uracil phosphoribosyltransferase gene gene1845 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01846 S100027_01847 S100027_01847 S100027_01847 1767339 1768643 + Uracil permease Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Transport of uracil in the cell. Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2. A. 40) subfamily gene gene1846 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01847 S100027_01848 S100027_01848 pyrB pyrB 1768787 1769707 + Aspartate carbamoyltransferase Pyrimidine biosynthesis%3B Transferase%3B Belongs to the ATCase/OTCase family%3B KEGG: bli:BL02273 aspartate carbamoyltransferase catalytic subunit gene gene1847 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01848 S100027_01849 S100027_01849 ura4 ura4 1769691 1770977 + Dihydroorotase Hydrolase%3B Metal-binding%3B Pyrimidine biosynthesis%3B Zinc%3B Belongs to the DHOase family. Type 2 subfamily%3B KEGG: bsu:BSU15500 dihydroorotase gene gene1848 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01849 S100027_01850 S100027_01850 S100027_01850 1770974 1772068 + Carbamoyl-phosphate synthase (glutamine-hydrolyzing) ATP-binding%3B Glutamine amidotransferase%3B Ligase%3B Nucleotide-binding%3B Pyrimidine biosynthesis%3B Belongs to the CarA family%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: bsu:BSU15510 carbamoyl-phosphate synthase small subunit%3B overlaps another CDS with the same product name gene gene1849 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01850 S100027_01851 S100027_01851 S100027_01851 1772053 1775265 + Carbamoyl-phosphate synthase (glutamine-hydrolyzing) Amino-acid biosynthesis%3B Arginine biosynthesis%3B ATP-binding%3B Ligase%3B Magnesium%3B Manganese%3B Metal-binding%3B Nucleotide-binding%3B Pyrimidine biosynthesis%3B Repeat%3B Belongs to the CarB family%3B Contains 2 ATP-grasp domains%3B KEGG: har:HEAR1165 carbamoyl-phosphate synthase large subunit%3B overlaps another CDS with the same product name gene gene1850 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01851 S100027_01852 S100027_01852 S100027_01852 1775262 1776032 + Dihydroorotate dehydrogenase B (NAD(+))%2C electron transfer subunit 2Fe-2S%3B Electron transport%3B FAD%3B Flavoprotein%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Pyrimidine biosynthesis%3B Transport%3B Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+)%3B Belongs to the PyrK family%3B Contains 1 FAD-binding FR-type domain gene gene1851 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01852 S100027_01853 S100027_01853 S100027_01853 1776029 1776967 + Dihydroorotate dehydrogenase (NAD(+)) Cytoplasm%3B Flavoprotein%3B FMN%3B NAD%3B Oxidoreductase%3B Pyrimidine biosynthesis%3B Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor%3B Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily%3B KEGG: bld:BLi01774 dihydroorotate dehydrogenase (NAD+) catalytic subunit gene gene1852 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01853 S100027_01854 S100027_01854 pyrF pyrF 1776936 1777655 + Orotidine-5'-phosphate decarboxylase Decarboxylase%3B Lyase%3B Pyrimidine biosynthesis%3B Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)%3B Belongs to the OMP decarboxylase family. Type 1 subfamily%3B KEGG: eco:b1281 orotidine-5'-phosphate decarboxylase gene gene1853 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01854 S100027_01855 S100027_01855 pyrE pyrE 1777652 1778281 + Orotate phosphoribosyltransferase Glycosyltransferase%3B Magnesium%3B Pyrimidine biosynthesis%3B Transferase%3B Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate%2C leading to the formation of orotidine monophosphate (OMP)%3B Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily%3B KEGG: bli:BL02280 orotate phosphoribosyltransferase gene gene1854 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01855 S100027_01856 S100027_01856 S100027_01856 1778627 1778770 + hypothetical protein gene gene1855 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01856 S100027_01857 S100027_01857 cysH cysH 1779017 1779559 + Phosphoadenylyl-sulfate reductase (thioredoxin) Cytoplasm%3B Oxidoreductase%3B Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily%3B KEGG: bsu:BSU15570 phosphoadenosine phosphosulfate reductase gene gene1856 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01857 S100027_01858 S100027_01858 S100027_01858 1779571 1780635 + Sulfate permease CysP Cell membrane%3B Membrane%3B Sulfate transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the import of sulfate%3B Belongs to the inorganic phosphate transporter (PiT) (TC 2. A. 20) family gene gene1857 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01858 S100027_01859 S100027_01859 met3 met3 1780661 1781797 + Sulfate adenylyltransferase ATP-binding%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase%3B Belongs to the sulfate adenylyltransferase family%3B KEGG: bsu:BSU15590 sulfate adenylyltransferase gene gene1858 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01859 S100027_01860 S100027_01860 cysC cysC 1781811 1782404 + Adenylyl-sulfate kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Catalyzes the synthesis of activated sulfate%3B Belongs to the APS kinase family%3B KEGG: sun:SUN_1719 adenylylsulfate kinase gene gene1859 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01860 S100027_01861 S100027_01861 cobA cobA 1782556 1783329 + Uroporphyrinogen-III C-methyltransferase Cobalamin biosynthesis%3B Methyltransferase%3B Porphyrin biosynthesis%3B S-adenosyl-L-methionine%3B Transferase%3B Catalyzes both methylations at C-2 and C-7 of uroporphyrinogen III leading to precorrin-1 and precorrin-%3B their oxidative esterification gives respectively factor I octamethyl ester and sirohydrochlorin. Belongs to the precorrin methyltransferase family%3B KEGG: shl:Shal_3534 uroporphyrin-III C-methyltransferase gene gene1860 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01861 S100027_01862 S100027_01862 sirB sirB 1783331 1784116 + Sirohydrochlorin ferrochelatase Iron%3B Lyase%3B Metal-binding%3B Porphyrin biosynthesis%3B Chelates iron to the siroheme precursor%3B Belongs to the CbiX family. SirB subfamily%3B KEGG: bsu:BSU15620 sirohydrochlorin ferrochelatase gene gene1861 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01862 S100027_01863 S100027_01863 met8 met8 1784097 1784591 + Precorrin-2 dehydrogenase Cobalamin biosynthesis%3B Lyase%3B Methyltransferase%3B Multifunctional enzyme%3B NAD%3B Oxidoreductase%3B Phosphoprotein%3B Porphyrin biosynthesis%3B S-adenosyl-L-methionine%3B Transferase%3B Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally%2C it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme%3B In the N-terminal sectio%3B belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family%3B In the C-terminal sectio%3B belongs to the precorrin methyltransferase family%3B KEGG: bli:BL02289 precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase gene gene1862 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01863 S100027_01864 S100027_01864 S100027_01864 1784612 1786324 - uncharacterized protein Coiled coil%3B Belongs to the NEMF family gene gene1863 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01864 S100027_01865 S100027_01865 S100027_01865 1786471 1789143 + Calcium-transporting ATPase ATP-binding%3B Calcium%3B Calcium transport%3B Cell membrane%3B Hydrolase%3B Ion transport%3B Magnesium%3B Membrane%3B Metal-binding%3B Nucleotide-binding%3B Phosphoprotein%3B Transmembrane%3B Transmembrane helix%3B Transport%3B This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium%3B Belongs to the cation transport ATPase (P-type) (TC 3. A. 3) family. Type IIA subfamily%3B KEGG: bsu:BSU15650 Ca2+-transporting ATPase gene gene1864 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01865 S100027_01866 S100027_01866 S100027_01866 1789245 1790129 + UPF0701 protein YloC Belongs to the UPF0701 family gene gene1865 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01866 S100027_01867 S100027_01867 S100027_01867 1790205 1790474 + UPF0296 protein Belongs to the UPF0296 family gene gene1866 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01867 S100027_01868 S100027_01868 S100027_01868 1790482 1791096 + Guanylate kinase ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Essential for recycling GMP and indirectly%2C cGMP%3B Belongs to the guanylate kinase family%3B Contains 1 guanylate kinase-like domain%3B KEGG: bsu:BSU15680 guanylate kinase gene gene1867 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01868 S100027_01869 S100027_01869 rpoZ rpoZ 1791099 1791299 + DNA-directed RNA polymerase DNA-directed RNA polymerase%3B Nucleotidyltransferase%3B Transcription%3B Transferase%3B Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits%3B Belongs to the RNA polymerase subunit omega family%3B KEGG: bsu:BSU15690 DNA-directed RNA polymerase subunit omega gene gene1868 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01869 S100027_01870 S100027_01870 S100027_01870 1791381 1792598 + Phosphopantothenoylcysteine decarboxylase Decarboxylase%3B Flavoprotein%3B FMN%3B Ligase%3B Lyase%3B Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine%2C in the latter compound is decarboxylated to form 4'-phosphopantotheine (By similarity)%3B In the N-terminal sectio%3B belongs to the HFCD (homo- oligomeric flavin containing Cys decarboxylase) superfamily%3B In the C-terminal sectio%3B belongs to the PPC synthetase family%3B KEGG: hpaz:K756_08760 phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase gene gene1869 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01870 S100027_01871 S100027_01871 priA priA 1792595 1795012 + Primosomal protein N' ATP-binding%3B DNA replication%3B DNA-binding%3B Helicase%3B Hydrolase%3B Metal-binding%3B Nucleotide-binding%3B Primosome%3B Zinc%3B Zinc-finger%3B Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex%2C via its helicase activity%2C and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA%3B Belongs to the helicase family. PriA subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bsu:BSU15710 primosomal protein N' (replication factor Y) (superfamily II helicase)%3B Acting on ATP%3B involved in cellular and subcellular movement gene gene1870 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01871 S100027_01872 S100027_01872 S100027_01872 1795042 1795524 + Peptide deformylase Hydrolase%3B Iron%3B Metal-binding%3B Protein biosynthesis%3B Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions%3B Belongs to the polypeptide deformylase family%3B KEGG: mes:Meso_0394 peptide deformylase gene gene1871 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01872 S100027_01873 S100027_01873 S100027_01873 1795529 1796479 + Methionyl-tRNA formyltransferase Protein biosynthesis%3B Transferase%3B Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by: (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP%3B Belongs to the Fmt family%3B KEGG: caj:CIG1485E_1484 methionyl-tRNA formyltransferase gene gene1872 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01873 S100027_01874 S100027_01874 rsmB rsmB 1796463 1797815 + 16S rRNA (cytosine(967)-C(5))-methyltransferase Cytoplasm%3B Methyltransferase%3B Ribosome biogenesis%3B RNA-binding%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family%3B KEGG: bli:BL02299 16S rRNA (cytosine967-C5)-methyltransferase gene gene1873 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01874 S100027_01875 S100027_01875 rlmN rlmN 1797815 1798900 + 23S rRNA (adenine(2503)-C(2))-methyltransferase 4Fe-4S%3B Cytoplasm%3B Disulfide bond%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B tRNA processing%3B Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs%3B Belongs to the radical SAM superfamily. RlmN family%3B KEGG: bli:BL02300 23S rRNA (adenine2503-C2)-methyltransferase gene gene1874 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01875 S100027_01876 S100027_01876 S100027_01876 1798908 1799672 + Protein-serine/threonine phosphatase Hydrolase%3B Manganese%3B Metal-binding%3B Protein phosphatase%3B Sporulation%3B Protein phosphatase that dephosphorylates PrkC and FusA (elongation factor G). PrpC and prkC are cotranscribed%2C which suggests that they form a functional couple in vivo%2C PrpC's primary role being possibly to counter the action of PrkC. May be involved in sporulation and biofilm formation. Does not seem to be involved in stress response%3B Contains 1 PPM-type phosphatase domain%3B KEGG: bsu:BSU15760 protein phosphatase gene gene1875 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01876 S100027_01877 S100027_01877 S100027_01877 1799666 1801639 + Non-specific serine/threonine protein kinase ATP-binding%3B Germination%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Repeat%3B Serine/threonine-protein kinase%3B Signal-anchor%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Protein kinase that is responsible for triggering spore germination in response to muropeptides%2C signaling bacteria to exit dormancy. Autophosphorylates and phosphorylates FusA (EF-G%2C elongation factor G%3B the latter modification is likely necessary for germination in response to peptidoglycan. PrkC is a substrate in vitro of the cotranscribed phosphatase PrpC%2C which suggests that they form a functional couple in vivo. Might also be involved in sporulation and biofilm formation. Does not seem to be involved in stress response%3B Belongs to the protein kinase superfamily. Ser/Thr protein kinase family%3B Contains 3 PASTA domains%3B Contains 1 protein kinase domain%3B KEGG: bsu:BSU15770 serine/threonine protein kinase%2C bacterial gene gene1876 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01877 S100027_01878 S100027_01878 S100027_01878 1801652 1802536 + Putative ribosome bioproteinis GTPase RsgA GTP-binding%3B Hydrolase%3B Metal-binding%3B Nucleotide-binding%3B Zinc%3B May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover%3B Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily%3B Contains 1 CP-type G (guanine nucleotide-binding) domain%3B KEGG: bli:BL02304 ribosome biogenesis GTPase%3B In phosphorus-containing anhydrides gene gene1877 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01878 S100027_01879 S100027_01879 S100027_01879 1802540 1803196 + Ribulose-phosphate 3-epimerase Calvin cycle%3B Carbohydrate metabolism%3B Cobalt%3B Iron%3B Isomerase%3B Manganese%3B Metal-binding%3B Zinc%3B Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate%3B Belongs to the ribulose-phosphate 3-epimerase family%3B KEGG: cjm:CJM1_0433 ribulose-phosphate 3-epimerase gene gene1878 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01879 S100027_01880 S100027_01880 thiN thiN 1803272 1803916 + Thiamine diphosphokinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate. Belongs to the thiamine pyrophosphokinase family%3B KEGG: bsu:BSU15800 thiamine pyrophosphokinase gene gene1879 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01880 S100027_01881 S100027_01881 S100027_01881 1804187 1804375 - 50S ribosomal protein L28 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L28P family gene gene1880 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01881 S100027_01882 S100027_01882 S100027_01882 1804663 1805025 + uncharacterized protein Belongs to the asp23 family gene gene1881 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01882 S100027_01883 S100027_01883 S100027_01883 1805043 1806713 + uncharacterized protein Contains 1 DhaL domain gene gene1882 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01883 S100027_01884 S100027_01884 sdaA sdaA 1806887 1807549 + L-serine ammonia-lyase 4Fe-4S%3B Gluconeogenesis%3B Iron%3B Iron-sulfur%3B Lyase%3B Metal-binding%3B Belongs to the iron-sulfur dependent L-serine dehydratase family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU15850 L-serine dehydratase gene gene1883 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01884 S100027_01885 S100027_01885 S100027_01885 1807568 1808470 + L-serine ammonia-lyase 4Fe-4S%3B Gluconeogenesis%3B Iron%3B Iron-sulfur%3B Lyase%3B Metal-binding%3B Belongs to the iron-sulfur dependent L-serine dehydratase family%3B KEGG: bsu:BSU15860 L-serine dehydratase gene gene1884 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01885 S100027_01886 S100027_01886 recG recG 1808448 1810496 + DNA helicase ATP-binding%3B DNA damage%3B DNA recombination%3B DNA repair%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) (By similarity)%3B Belongs to the helicase family. RecG subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bli:BL02311 ATP-dependent DNA helicase RecG gene gene1885 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01886 S100027_01887 S100027_01887 S100027_01887 1810643 1811179 + Transcription factor FapR DNA-binding%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism%3B Belongs to the FapR family gene gene1886 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01887 S100027_01888 S100027_01888 plsX plsX 1811197 1812189 + Glycerol-3-phosphate 1-O-acyltransferase Cytoplasm%3B Lipid biosynthesis%3B Lipid metabolism%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor%2C but not acyl-CoA%3B Belongs to the PlsX family%3B KEGG: vfi:VF_1743 glycerol-3-phosphate acyltransferase PlsX gene gene1887 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01888 S100027_01889 S100027_01889 fabD fabD 1812207 1813166 + [Acyl-carrier-protein] S-malonyltransferase Acyltransferase%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Transferase%3B Belongs to the FabD family%3B KEGG: rah:Rahaq_2956 (acyl-carrier-protein) S-malonyltransferase gene gene1888 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01889 S100027_01890 S100027_01890 S100027_01890 1813153 1813896 + 3-oxoacyl-[acyl-carrier-protein] reductase Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B NADP%3B Oxidoreductase%3B Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products%2C the first reductive step in the elongation cycle of fatty acid biosynthesis%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: ahd:AI20_12755 3-oxoacyl-(acyl-carrier protein) reductase gene gene1889 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01890 S100027_01891 S100027_01891 S100027_01891 1813973 1814206 + Acyl carrier protein Cytoplasm%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Phosphopantetheine%3B Phosphoprotein%3B Carrier of the growing fatty acid chain in fatty acid biosynthesis%3B Contains 1 acyl carrier domain gene gene1890 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01891 S100027_01892 S100027_01892 rnt1 rnt1 1814348 1815097 + Ribonuclease III Cytoplasm%3B Endonuclease%3B Hydrolase%3B Magnesium%3B Metal-binding%3B mRNA processing%3B Nuclease%3B RNA-binding%3B rRNA processing%3B rRNA-binding%3B tRNA processing%3B Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs%2C and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism%3B Contains 1 DRBM (double-stranded RNA-binding) domain%3B Contains 1 RNase III domain%3B KEGG: bsu:BSU15930 ribonuclease III gene gene1891 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01892 S100027_01893 S100027_01893 S100027_01893 1815197 1818757 + Chromosome partition protein Smc ATP-binding%3B Coiled coil%3B Cytoplasm%3B DNA-binding%3B Nucleotide-binding%3B Required for chromosome condensation and partitioning%3B Belongs to the SMC family gene gene1892 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01893 S100027_01894 S100027_01894 S100027_01894 1818774 1819760 + Signal recognition particle receptor FtsY Cell membrane%3B Cytoplasm%3B GTP-binding%3B Membrane%3B Nucleotide-binding%3B Receptor%3B Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)%3B Belongs to the GTP-binding SRP family. FtsY subfamily gene gene1893 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01894 S100027_01895 S100027_01895 S100027_01895 1819894 1820217 + UPF0122 protein Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein%3B Belongs to the UPF0122 family gene gene1894 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01895 S100027_01896 S100027_01896 S100027_01896 1820233 1821573 + Signal recognition particle protein Cytoplasm%3B GTP-binding%3B Nucleotide-binding%3B Ribonucleoprotein%3B RNA-binding%3B Signal recognition particle%3B Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane%2C the hydrolysis of GTP by both Ffh and FtsY%2C and the dissociation of the SRP-FtsY complex into the individual components (Probable)%3B Belongs to the GTP-binding SRP family. SRP54 subfamily gene gene1895 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01896 S100027_01897 S100027_01897 S100027_01897 1821681 1821953 + 30S ribosomal protein S16 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein S16P family gene gene1896 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01897 S100027_01898 S100027_01898 S100027_01898 1821953 1822198 + UPF0109 protein YlqC RNA-binding%3B Belongs to the UPF0109 family%3B Contains 1 KH domain gene gene1897 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01898 S100027_01899 S100027_01899 S100027_01899 1822336 1822722 + uncharacterized protein gene gene1898 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01899 S100027_01900 S100027_01900 S100027_01900 1822727 1823251 + Ribosome maturation factor RimM Chaperone%3B Cytoplasm%3B Ribosome biogenesis%3B An accessory protein needed during the final step in the assembly of 30S ribosomal subunit%2C possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes%3B Belongs to the RimM family%3B Contains 1 PRC barrel domain gene gene1899 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01900 S100027_01901 S100027_01901 trmD trmD 1823248 1823979 + tRNA (guanine(37)-N(1))-methyltransferase Cytoplasm%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B tRNA processing%3B Specifically methylates guanosine-37 in various tRNAs%3B Belongs to the RNA methyltransferase TrmD family%3B KEGG: dno:DNO_1009 tRNA (guanine37-N1)-methyltransferase gene gene1900 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01901 S100027_01902 S100027_01902 S100027_01902 1824118 1824465 + 50S ribosomal protein L19 Ribonucleoprotein%3B Ribosomal protein%3B This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site%3B Belongs to the ribosomal protein L19P family gene gene1901 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01902 S100027_01903 S100027_01903 S100027_01903 1824580 1825431 + Ribosome bioproteinis GTPase Cytoplasm%3B GTP-binding%3B Hydrolase%3B Nucleotide-binding%3B Ribosome biogenesis%3B RNA-binding%3B Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity. Binds to the 23S rRNA (By similarity)%3B Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily%3B Contains 1 CP-type G (guanine nucleotide-binding) domain gene gene1902 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01903 S100027_01904 S100027_01904 rnhB rnhB 1825509 1826276 + Ribonuclease H Cytoplasm%3B Endonuclease%3B Hydrolase%3B Manganese%3B Metal-binding%3B Nuclease%3B Endonuclease that specifically degrades the RNA of RNA- DNA hybrids%3B Belongs to the RNase HII family%3B KEGG: bsu:BSU16060 ribonuclease HII gene gene1903 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01904 S100027_01905 S100027_01905 S100027_01905 1826292 1827989 + uncharacterized protein overlaps another CDS with the same product name gene gene1904 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01905 S100027_01906 S100027_01906 S100027_01906 1827986 1828267 + uncharacterized protein overlaps another CDS with the same product name gene gene1905 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01906 S100027_01907 S100027_01907 sucC sucC 1828444 1829604 + Succinate--CoA ligase (ADP-forming) ATP-binding%3B Ligase%3B Magnesium%3B Manganese%3B Metal-binding%3B Nucleotide-binding%3B Tricarboxylic acid cycle%3B Belongs to the succinate/malate CoA ligase beta subunit family%3B Contains 1 ATP-grasp domain%3B KEGG: hap:HAPS_0656 succinyl-CoA synthetase beta subunit gene gene1906 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01907 S100027_01908 S100027_01908 mtkB mtkB 1829623 1830525 + Malate--CoA ligase ATP-binding%3B Ligase%3B Nucleotide-binding%3B Phosphoprotein%3B Tricarboxylic acid cycle%3B Belongs to the succinate/malate CoA ligase alpha subunit family%3B KEGG: mmt:Metme_2693 malate-CoA ligase subunit alpha gene gene1907 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01908 S100027_01909 S100027_01909 S100027_01909 1830639 1831541 + Protein smf Belongs to the smf family gene gene1908 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01909 S100027_01910 S100027_01910 topA topA 1831746 1833821 + DNA topoisomerase DNA-binding%3B Isomerase%3B Magnesium%3B Metal-binding%3B Repeat%3B Topoisomerase%3B Zinc%3B Zinc-finger%3B Releases the supercoiling and torsional tension of DNA%2C which is introduced during the DNA replication and transcription%2C by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme%2C resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand%2C thus removing DNA supercoils. Finally%2C in the religation step%2C the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone%3B Belongs to the type IA topoisomerase family%3B Contains 1 Toprim domain%3B KEGG: bsu:BSU16120 DNA topoisomerase I gene gene1909 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01910 S100027_01911 S100027_01911 S100027_01911 1833897 1835201 + Methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-methyltransferase(FADH(2)-oxidizing) Cytoplasm%3B FAD%3B Flavoprotein%3B Methyltransferase%3B Transferase%3B tRNA processing%3B Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs%3B Belongs to the MnmG family. TrmFO subfamily%3B KEGG: mor:MOC_1952 methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase gene gene1910 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01911 S100027_01912 S100027_01912 S100027_01912 1835268 1836182 + Tyrosine recombinase XerC Cell cycle%3B Cell division%3B Chromosome partition%3B Cytoplasm%3B DNA integration%3B DNA recombination%3B DNA-binding%3B Site-specific tyrosine recombinase%2C which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids%3B Belongs to the 'phage' integrase family. XerC subfamily gene gene1911 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01912 S100027_01913 S100027_01913 hslV hslV 1836196 1836741 + HslU--HslV peptidase Cytoplasm%3B Hydrolase%3B Metal-binding%3B Protease%3B Serine protease%3B Sodium%3B Protease subunit of a proteasome-like degradation complex%3B Belongs to the peptidase T1B family. HslV subfamily%3B KEGG: rhd:R2APBS1_3955 ATP-dependent HslUV protease%2C peptidase subunit HslV gene gene1912 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01913 S100027_01914 S100027_01914 S100027_01914 1836758 1838161 + ATP-dependent protease ATPase subunit ClpY ATP-binding%3B Chaperone%3B Cytoplasm%3B Nucleotide-binding%3B ATPase subunit of a proteasome-like degradation comple%3B this subunit has chaperone activity%3B Belongs to the ClpX chaperone family. HslU subfamily gene gene1913 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01914 S100027_01915 S100027_01915 S100027_01915 1838200 1838979 + GTP-sensing transcriptional pleiotropic repressor CodY Cytoplasm%3B DNA-binding%3B GTP-binding%3B Nucleotide-binding%3B Phosphoprotein%3B Repressor%3B Transcription%3B Transcription regulation%3B DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor%3B Belongs to the CodY family gene gene1914 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01915 S100027_01916 S100027_01916 S100027_01916 1839097 1839234 - hypothetical protein gene gene1915 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01916 S100027_01917 S100027_01917 S100027_01917 1839333 1839722 + Flagellar basal body rod protein FlgB Bacterial flagellum%3B Structural component of flagellum%2C the bacterial motility apparatus. Part of the rod structure of flagellar basal body%3B Belongs to the flagella basal body rod proteins family gene gene1916 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01917 S100027_01918 S100027_01918 S100027_01918 1839722 1840174 + Flagellar basal-body rod protein FlgC Bacterial flagellum%3B Belongs to the flagella basal body rod proteins family gene gene1917 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01918 S100027_01919 S100027_01919 S100027_01919 1840188 1840505 + Flagellar hook-basal body complex protein FliE Bacterial flagellum%3B Belongs to the FliE family gene gene1918 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01919 S100027_01920 S100027_01920 S100027_01920 1840556 1842157 + Flagellar M-ring protein Bacterial flagellum%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B The M ring may be actively involved in energy transduction. Belongs to the FliF family gene gene1919 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01920 S100027_01921 S100027_01921 S100027_01921 1842171 1843187 + Flagellar motor switch protein FliG Bacterial flagellum%3B Cell membrane%3B Chemotaxis%3B Flagellar rotation%3B Membrane%3B One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliG family gene gene1920 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01921 S100027_01922 S100027_01922 S100027_01922 1843171 1843938 + putative flagellar assembly protein FliH Bacterial flagellum biogenesis%3B Bacterial flagellum protein export%3B Protein transport%3B Transport%3B Needed for flagellar regrowth and assembly. Belongs to the FliH family gene gene1921 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01922 S100027_01923 S100027_01923 fliI fliI 1843938 1845251 + H(+)-transporting two-sector ATPase ATP synthesis%3B ATP-binding%3B Bacterial flagellum biogenesis%3B Bacterial flagellum protein export%3B Cytoplasm%3B Hydrogen ion transport%3B Hydrolase%3B Ion transport%3B Nucleotide-binding%3B Protein transport%3B Transport%3B Probable catalytic subunit of a protein translocase for flagellum-specific export%2C or a proton translocase involved in local circuits at the flagellum. Belongs to the ATPase alpha/beta chains family%3B KEGG: bli:BL01269 flagellum-specific ATP synthase gene gene1922 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01923 S100027_01924 S100027_01924 S100027_01924 1845254 1845697 + Flagellar FliJ protein Bacterial flagellum biogenesis%3B Bacterial flagellum protein export%3B Cell membrane%3B Chemotaxis%3B Membrane%3B Protein transport%3B Transport%3B Flagellar protein that affects chemotactic events%3B Belongs to the FliJ family gene gene1923 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01924 S100027_01925 S100027_01925 S100027_01925 1845711 1846322 + FlaA locus 22.9 kDa protein Bacterial flagellum biogenesis. gene gene1924 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01925 S100027_01926 S100027_01926 S100027_01926 1846324 1847703 + putative flagellar hook-length control protein Bacterial flagellum biogenesis%3B Controls the length of the flagellar hook%3B Belongs to the FliK family gene gene1925 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01926 S100027_01927 S100027_01927 S100027_01927 1847703 1848170 + FlaA locus uncharacterized protein YlxG Bacterial flagellum biogenesis%3B Belongs to the FlgD family gene gene1926 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01927 S100027_01928 S100027_01928 S100027_01928 1848198 1848989 + Flagellar hook protein FlgE Bacterial flagellum%3B Belongs to the flagella basal body rod proteins family gene gene1927 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01928 S100027_01929 S100027_01929 S100027_01929 1849244 1849675 + Flagellar protein FliL Cell membrane%3B Chemotaxis%3B Flagellar rotation%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Controls the rotational direction of flagella during chemotaxis. Belongs to the FliL family gene gene1928 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01929 S100027_01930 S100027_01930 S100027_01930 1849711 1850709 + Flagellar motor switch protein FliM Bacterial flagellum%3B Cell membrane%3B Chemotaxis%3B Flagellar rotation%3B Membrane%3B One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliM family gene gene1929 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01930 S100027_01931 S100027_01931 S100027_01931 1850699 1851832 + Flagellar motor switch phosphatase FliY Cell membrane%3B Chemotaxis%3B Flagellar rotation%3B Hydrolase%3B Membrane%3B Component of the flagellar switch. Binds CheY-P and increases its hydrolysis rate in vitro. May function constitutively to remove CheY-P around the flagellar switch to maintain an optimal level of CheY-P whereas CheC may function after addition of an attractant to cope with increased levels of CheY-P%3B Belongs to the FliN/MopA/SpaO family gene gene1930 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01931 S100027_01932 S100027_01932 S100027_01932 1851859 1852221 + Chemotaxis protein CheY Chemotaxis%3B Cytoplasm%3B Magnesium%3B Metal-binding%3B Phosphoprotein%3B Two-component regulatory system%3B Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. Phosphorylated CheY interacts with the flagella switch components FliM and FliY%2C which causes counterclockwise rotation of the flagella%2C resulting in smooth swimming%3B Contains 1 response regulatory domain gene gene1931 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01932 S100027_01933 S100027_01933 S100027_01933 1852234 1852908 + Flagellar biosynthetic protein FliZ Bacterial flagellum biogenesis%3B Cell membrane%3B Membrane%3B Signal%3B Transmembrane%3B Transmembrane helix. gene gene1932 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01933 S100027_01934 S100027_01934 S100027_01934 1852901 1853566 + Flagellar biosynthetic protein FliP Bacterial flagellum biogenesis%3B Bacterial flagellum protein export%3B Cell membrane%3B Membrane%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Plays a role in the flagellum-specific transport system%3B Belongs to the FliP/MopC/SpaP family gene gene1933 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01934 S100027_01935 S100027_01935 S100027_01935 1853582 1853851 + Flagellar biosynthetic protein FliQ Bacterial flagellum%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family gene gene1934 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01935 S100027_01936 S100027_01936 S100027_01936 1853859 1854635 + Flagellar biosynthetic protein FliR Bacterial flagellum%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family gene gene1935 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01936 S100027_01937 S100027_01937 S100027_01937 1854632 1855714 + Flagellar biosynthetic protein FlhB Bacterial flagellum biogenesis%3B Bacterial flagellum protein export%3B Cell membrane%3B Membrane%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B May be involved in the export of flagellum proteins. Belongs to the type III secretion exporter family gene gene1936 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01937 S100027_01938 S100027_01938 S100027_01938 1855748 1857784 + Flagellar biosynthesis protein FlhA Bacterial flagellum biogenesis%3B Bacterial flagellum protein export%3B Cell membrane%3B Membrane%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the export of flagellum proteins. Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family gene gene1937 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01938 S100027_01939 S100027_01939 S100027_01939 1857781 1858893 + Flagellar biosynthesis protein FlhF Bacterial flagellum biogenesis%3B Bacterial flagellum protein export%3B Cell membrane%3B GTP-binding%3B Membrane%3B Nucleotide-binding%3B Protein transport%3B Transport%3B Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum. Belongs to the GTP-binding SRP family gene gene1938 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01939 S100027_01940 S100027_01940 S100027_01940 1858890 1859783 + Flagellum site-determining protein YlxH ATP-binding%3B Bacterial flagellum biogenesis%3B Nucleotide-binding%3B Involved in the placement and assembly of flagella (By similarity). Activates the SRP-GTPase activity of FlhF%3B Belongs to the ParA family gene gene1939 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01940 S100027_01941 S100027_01941 S100027_01941 1859780 1860853 + Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon Chemotaxis%3B Cytoplasm%3B Hydrolase%3B Phosphoprotein%3B Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene1940 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01941 S100027_01942 S100027_01942 cheA cheA 1860859 1862880 + Histidine kinase ATP-binding%3B Chemotaxis%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Two-component regulatory system%3B Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylate%3B it can transfer its phosphate group to CheB%2C CheY or CheV%3B Contains 1 cheW-like domain%3B Contains 1 histidine kinase domain%3B Contains 1 HPt domain%3B KEGG: xcc:XCC2700 two-component system%2C chemotaxis family%2C sensor kinase CheA gene gene1941 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01942 S100027_01943 S100027_01943 S100027_01943 1862904 1863380 + Chemotaxis protein CheW Chemotaxis%3B Cytoplasm%3B Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheV and CheW are involved in the coupling of the methyl-accepting chemoreceptors to the central two-component kinase Che%3B they are both necessary for efficient chemotaxis%3B Contains 1 cheW-like domain gene gene1942 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01943 S100027_01944 S100027_01944 S100027_01944 1863391 1864020 + CheY-P phosphatase CheC Chemotaxis%3B Hydrolase%3B Involved in restoring normal CheY-P levels following the addition of attractant by increasing the rate of CheY-P hydrolysis. Is only 6%25 as active as FliY%2C which indicates that CheC may function after addition of an attractant to cope with increased levels of CheY-P whereas FliY may function constitutively to remove CheY-P around the flagellar switch to maintain an optimal level of CheY-P. In addition%2C it was shown to prevent methylation of the methyl-accepting chemotaxis proteins (MCPs). Inhibits CheD%3B Belongs to the CheC family gene gene1943 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01944 S100027_01945 S100027_01945 cheD cheD 1864017 1864523 + Protein-glutamine glutaminase Chemotaxis%3B Hydrolase%3B Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase (By similarity)%3B Belongs to the CheD family%3B KEGG: bli:BL01247 chemotaxis protein CheD gene gene1944 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01945 S100027_01946 S100027_01946 S100027_01946 1864546 1865310 + RNA polymerase sigma-D factor DNA-binding%3B Sigma factor%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This alternative sigma factor is required for the transcription of the flagellin and motility genes as well as for wild-type chemotaxis. Belongs to the sigma-70 factor family gene gene1945 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01946 S100027_01947 S100027_01947 S100027_01947 1865405 1865917 + Swarming motility protein SwrB Required for swarming motility and for maximal sigma-D activity gene gene1946 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01947 S100027_01948 S100027_01948 S100027_01948 1866071 1866811 + 30S ribosomal protein S2 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein S2P family gene gene1947 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01948 S100027_01949 S100027_01949 S100027_01949 1866912 1867793 + Elongation factor Ts Cytoplasm%3B Elongation factor%3B Protein biosynthesis%3B Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA. EF- Tu. GTP complex up to the GTP hydrolysis stage on the ribosome%3B Belongs to the EF-Ts family gene gene1948 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01949 S100027_01950 S100027_01950 pyrH pyrH 1867943 1868665 + UMP kinase Allosteric enzyme%3B ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Pyrimidine biosynthesis%3B Transferase%3B Catalyzes the reversible phosphorylation of UMP to UDP%3B Belongs to the UMP kinase family%3B KEGG: ssan:NX02_14365 uridylate kinase gene gene1949 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01950 S100027_01951 S100027_01951 S100027_01951 1868667 1869224 + Ribosome-recycling factor Cytoplasm%3B Protein biosynthesis%3B Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another%3B Belongs to the RRF family gene gene1950 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01951 S100027_01952 S100027_01952 uppS uppS 1869354 1870136 + Ditrans%2Cpolycis-undecaprenyl-diphosphate synthase ((2E%2C6E)-farnesyl-diphosphate specific) Magnesium%3B Metal-binding%3B Transferase%3B Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids%3B Belongs to the UPP synthase family%3B KEGG: bsu:BSU16530 undecaprenyl diphosphate synthase gene gene1951 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01952 S100027_01953 S100027_01953 cds1 cds1 1870149 1870952 + Phosphatidate cytidylyltransferase Cell membrane%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Nucleotidyltransferase%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Belongs to the CDS family%3B KEGG: bsu:BSU16540 phosphatidate cytidylyltransferase gene gene1952 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01953 S100027_01954 S100027_01954 S100027_01954 1870999 1872150 + 1-deoxy-D-xylulose-5-phosphate reductoisomerase Isoprene biosynthesis%3B Metal-binding%3B NADP%3B Oxidoreductase%3B Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)%3B Belongs to the DXR family%3B KEGG: pat:Patl_1255 1-deoxy-D-xylulose-5-phosphate reductoisomerase gene gene1953 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01954 S100027_01955 S100027_01955 rseP rseP 1872163 1873422 + putative protease eep Cell membrane%3B Hydrolase%3B Membrane%3B Metal-binding%3B Metalloprotease%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Zinc%3B Involved in production of the peptide pheromone cAD1. Belongs to the peptidase M50B family%3B Contains 1 PDZ (DHR) domain%3B KEGG: tcx:Tcr_1279 regulator of sigma E protease%3B Metalloendopeptidases gene gene1954 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01955 S100027_01956 S100027_01956 parS parS 1873532 1875250 + Proline--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine%2C to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS%3B Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily%3B KEGG: bli:BL01235 prolyl-tRNA synthetase gene gene1955 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01956 S100027_01957 S100027_01957 polC polC 1875339 1879655 + DNA-directed DNA polymerase Antibiotic resistance%3B Cytoplasm%3B DNA replication%3B DNA-directed DNA polymerase%3B Exonuclease%3B Hydrolase%3B Nuclease%3B Nucleotidyltransferase%3B Transferase%3B Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. Belongs to the DNA polymerase type-C family. PolC subfamily%3B Contains 1 exonuclease domain%3B KEGG: bsut:BSUB_01790 DNA polymerase III subunit alpha%2C Gram-positive type gene gene1956 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01957 S100027_01958 S100027_01958 S100027_01958 1880070 1880345 + Cellulase Carbohydrate metabolism%3B Cellulose degradation%3B Glycosidase%3B Hydrolase%3B Polysaccharide degradation%3B Secreted%3B Signal%3B Belongs to the glycosyl hydrolase 9 (cellulase E) family%3B Contains 1 CBM3 (carbohydrate binding type-3) domain%3B KEGG: csc:Csac_1079 endoglucanase%3B overlaps another CDS with the same product name gene gene1957 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01958 S100027_01959 S100027_01959 S100027_01959 1880296 1882035 + Cellulase Carbohydrate metabolism%3B Cell wall biogenesis/degradation%3B Cellulose degradation%3B Glycoprotein%3B Glycosidase%3B Hydrolase%3B Polysaccharide degradation%3B Secreted%3B Signal%3B Belongs to the glycosyl hydrolase 9 (cellulase E) family%3B KEGG: csc:Csac_1079 endoglucanase%3B overlaps another CDS with the same product name gene gene1958 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01959 S100027_01960 S100027_01960 S100027_01960 1882063 1884177 + Cellulose 1%2C4-beta-cellobiosidase (non-reducing end) Carbohydrate metabolism%3B Cellulose degradation%3B Glycosidase%3B Hydrolase%3B Polysaccharide degradation%3B Signal%3B Belongs to the glycosyl hydrolase 48 (cellulase L) family%3B Contains 1 CBM3 (carbohydrate binding type-3) domain%3B KEGG: cth:Cthe_0071 cellulose 1%2C4-beta-cellobiosidase gene gene1959 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01960 S100027_01961 S100027_01961 S100027_01961 1884282 1885964 + Cellulase Carbohydrate metabolism%3B Cellulose degradation%3B Glycosidase%3B Hydrolase%3B Polysaccharide degradation%3B Signal%3B Has endoglucanase activity on carboxymethyl-cellulose (CMC)%2C xylan and lichenan%2C but not Avicel. Belongs to the glycosyl hydrolase 5 (cellulase A) family%3B Contains 1 dockerin domain%3B KEGG: bli:BL01230 endoglucanase gene gene1960 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01961 S100027_01962 S100027_01962 S100027_01962 1886028 1887215 + Mannan endo-1%2C4-beta-mannosidase Carbohydrate metabolism%3B Glycoprotein%3B Glycosidase%3B Hydrolase%3B Secreted%3B Signal%3B Endo-1%2C4-mannanase%2C a crucial enzyme for depolymerization of seed galactomannans and wood galactoglucomannans%3B Belongs to the glycosyl hydrolase 5 (cellulase A) family%3B KEGG: bli:BL01229 mannan endo-1%2C4-beta-mannosidase gene gene1961 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01962 S100027_01963 S100027_01963 S100027_01963 1887409 1887882 + Ribosome maturation factor RimP Cytoplasm%3B Ribosome biogenesis%3B Required for maturation of 30S ribosomal subunits%3B Belongs to the RimP family gene gene1962 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01963 S100027_01964 S100027_01964 S100027_01964 1887914 1889032 + Transcription termination/antitermination protein NusA Cytoplasm%3B RNA-binding%3B Transcription%3B Transcription antitermination%3B Transcription regulation%3B Transcription termination%3B Participates in both transcription termination and antitermination%3B Belongs to the NusA family%3B Contains 1 KH domain%3B Contains 1 S1 motif domain gene gene1963 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01964 S100027_01965 S100027_01965 S100027_01965 1889046 1889321 + uncharacterized protein gene gene1964 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01965 S100027_01966 S100027_01966 S100027_01966 1889322 1889624 + putative ribosomal protein YlxQ Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B RNA-binding protein that recognizes the K-turn motif present in ribosomal RNA%2C but also in box C/D and box C'/D' sRNAs%3B Belongs to the ribosomal protein L7Ae family gene gene1965 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01966 S100027_01967 S100027_01967 S100027_01967 1889645 1891795 + Translation initiation factor IF-2 Cytoplasm%3B GTP-binding%3B Initiation factor%3B Nucleotide-binding%3B Protein biosynthesis%3B One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene1966 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01967 S100027_01968 S100027_01968 S100027_01968 1891792 1892070 + uncharacterized protein gene gene1967 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01968 S100027_01969 S100027_01969 S100027_01969 1892089 1892442 + Ribosome-binding factor Cytoplasm%3B rRNA processing%3B Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA%3B Belongs to the RbfA family gene gene1968 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01969 S100027_01970 S100027_01970 truB truB 1892514 1893443 + tRNA pseudouridine(55) synthase Isomerase%3B tRNA processing%3B Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs%3B Belongs to the pseudouridine synthase TruB family. Type 1 subfamily%3B KEGG: ben:BOBLI757_107 tRNA pseudouridine55 synthase gene gene1969 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01970 S100027_01971 S100027_01971 ribF ribF 1893459 1894418 + Riboflavin kinase ATP-binding%3B FAD%3B Flavoprotein%3B FMN%3B Kinase%3B Multifunctional enzyme%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase%3B Belongs to the RibF family%3B KEGG: bsu:BSU16670 riboflavin kinase / FMN adenylyltransferase gene gene1970 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01971 S100027_01972 S100027_01972 S100027_01972 1894604 1894873 + 30S ribosomal protein S15 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B One of the primary rRNA binding proteins%2C it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA%3B Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome%3B Belongs to the ribosomal protein S15P family gene gene1971 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01972 S100027_01973 S100027_01973 S100027_01973 1895075 1897192 + Polyribonucleotide nucleotidyltransferase Cytoplasm%3B Magnesium%3B Metal-binding%3B Nucleotidyltransferase%3B RNA-binding%3B Transferase%3B Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction%3B Belongs to the polyribonucleotide nucleotidyltransferase family%3B Contains 1 KH domain%3B Contains 1 S1 motif domain%3B KEGG: bmx:BMS_1508 polyribonucleotide nucleotidyltransferase gene gene1972 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01973 S100027_01974 S100027_01974 S100027_01974 1897339 1898301 + uncharacterized protein Hydrolase%3B Signal%3B Belongs to the polysaccharide deacetylase family%3B KEGG: baci:B1NLA3E_02370 peptidoglycan-N-acetylmuramic acid deacetylase%3B In linear amides gene gene1973 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01974 S100027_01975 S100027_01975 pqqL pqqL 1898338 1899567 + putative zinc protease YmxG Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Zinc%3B Belongs to the peptidase M16 family%3B KEGG: ftu:FTT_1321 zinc protease%3B Metalloendopeptidases gene gene1974 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01975 S100027_01976 S100027_01976 S100027_01976 1899653 1899913 + uncharacterized protein Sporulation%3B Belongs to the YlmC/YmxH family gene gene1975 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01976 S100027_01977 S100027_01977 S100027_01977 1900056 1900955 + Dipicolinate synthase subunit NADP%3B Oxidoreductase%3B Sporulation%3B Together with DpaB%2C catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)%2C which constitutes up to 10%25 of the dry weight of the spore%3B overlaps another CDS with the same product name gene gene1976 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01977 S100027_01978 S100027_01978 S100027_01978 1900955 1901545 + Dipicolinate synthase subunit NADP%3B Oxidoreductase%3B Sporulation%3B Together with DpaA%2C catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)%2C which constitutes up to 10%25 of the dry weight of the spore%3B overlaps another CDS with the same product name gene gene1977 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01978 S100027_01979 S100027_01979 S100027_01979 1901672 1902712 + Aspartate-semialdehyde dehydrogenase Amino-acid biosynthesis%3B Diaminopimelate biosynthesis%3B Lysine biosynthesis%3B Methionine biosynthesis%3B NADP%3B Oxidoreductase%3B Phosphoprotein%3B Threonine biosynthesis%3B Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate%3B Belongs to the aspartate-semialdehyde dehydrogenase family%3B KEGG: bsu:BSU16750 aspartate-semialdehyde dehydrogenase gene gene1978 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01979 S100027_01980 S100027_01980 S100027_01980 1902803 1904017 + Aspartate kinase Alternative initiation%3B Amino-acid biosynthesis%3B ATP-binding%3B Diaminopimelate biosynthesis%3B Kinase%3B Lysine biosynthesis%3B Nucleotide-binding%3B Transferase%3B Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate%2C which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine%2C isoleucine and methionine%3B Belongs to the aspartokinase family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU16760 aspartate kinase gene gene1979 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01980 S100027_01981 S100027_01981 dapA dapA 1904048 1904917 + 4-hydroxy-tetrahydrodipicolinate synthase Amino-acid biosynthesis%3B Cytoplasm%3B Diaminopimelate biosynthesis%3B Lyase%3B Lysine biosynthesis%3B Schiff base%3B Catalyzes the condensation of (S)-aspartate-beta- semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)%3B Belongs to the DapA family%3B KEGG: bli:BL01208 4-hydroxy-tetrahydrodipicolinate synthase gene gene1980 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01981 S100027_01982 S100027_01982 S100027_01982 1905065 1906729 + Ribonuclease J2 Cytoplasm%3B Endonuclease%3B Exonuclease%3B Hydrolase%3B Metal-binding%3B Nuclease%3B RNA-binding%3B rRNA processing%3B Zinc%3B Endonucleolytically cleaves the 5'-leader sequence of certain mRNAs. Endonuclease digestion by the RNase J1/J2 complex occurs at a different site and in some cases more efficiently than J1 or J2 alone. The exonuclease activity of the J1/J2 complex is highly processive on substrates longer than 5 nucleotides%2C on shorter substrates is distributive. Plays a role in mRNA maturation and stability. Appears to have a limited effect on 16S rRNA maturation%2C despite its similarity to RNase J1. This subunit alone has very poor 5'-3' exonuclease activity%3B Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily%3B KEGG: bli:BL01207 ribonuclease J%3B Acting on ester bonds gene gene1981 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01982 S100027_01983 S100027_01983 S100027_01983 1906834 1907580 + Endopeptidase Clp Cytoplasm%3B Hydrolase%3B Protease%3B Protein transport%3B Translocation%3B Transport%3B Required for efficient translocation of pre-proteins across the membrane%3B Belongs to the peptidase S14 family. TepA subfamily%3B KEGG: nth:Nther_1461 ATP-dependent Clp protease%2C protease subunit gene gene1982 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01983 S100027_01984 S100027_01984 S100027_01984 1907577 1907792 + uncharacterized protein gene gene1983 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01984 S100027_01985 S100027_01985 S100027_01985 1907912 1910257 + DNA translocase FtsK ATP-binding%3B Cell cycle%3B Cell division%3B Cell membrane%3B Chromosome partition%3B DNA-binding%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site%2C which is located within the replication terminus region. Required for activation of the Xer recombinase%2C allowing activation of chromosome unlinking by recombination (By similarity)%3B Belongs to the FtsK/SpoIIIE/SftA family%3B Contains 1 FtsK domain gene gene1984 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01985 S100027_01986 S100027_01986 S100027_01986 1910390 1911115 + putative HTH-type transcriptional regulator YmfC DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH gntR-type DNA-binding domain gene gene1985 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01986 S100027_01987 S100027_01987 S100027_01987 1911251 1912456 + Bacillibactin exporter Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in secretion of bacillibactin%3B Belongs to the major facilitator superfamily gene gene1986 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01987 S100027_01988 S100027_01988 S100027_01988 1912598 1913878 + putative inactive metalloprotease YmfF Metal-binding%3B Zinc%3B Belongs to the peptidase M16 family%3B KEGG: tid:Thein_0626 zinc protease%3B Metalloendopeptidases gene gene1987 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01988 S100027_01989 S100027_01989 S100027_01989 1913875 1915161 + Insulysin Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Zinc%3B Belongs to the peptidase M16 family%3B KEGG: bcz:BCZK3546 insulysin gene gene1988 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01989 S100027_01990 S100027_01990 S100027_01990 1915249 1915980 + 3-oxoacyl-[acyl-carrier-protein] reductase Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: vha:VIBHAR_02553 3-oxoacyl-(acyl-carrier protein) reductase gene gene1989 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01990 S100027_01991 S100027_01991 S100027_01991 1916051 1916308 + uncharacterized protein gene gene1990 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01991 S100027_01992 S100027_01992 S100027_01992 1916556 1917347 + uncharacterized protein Contains 1 ACT domain gene gene1991 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01992 S100027_01993 S100027_01993 S100027_01993 1917365 1918267 + putative membrane protein YmfM Cell membrane%3B Coiled coil%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1992 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01993 S100027_01994 S100027_01994 pgsA pgsA 1918334 1918915 + CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Cell membrane%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B This protein catalyzes the committed step to the synthesis of the acidic phospholipids%3B Belongs to the CDP-alcohol phosphatidyltransferase class-I family%3B KEGG: bsu:BSU16920 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase gene gene1993 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01994 S100027_01995 S100027_01995 pncC pncC 1918935 1920185 + Nicotinamide-nucleotide amidase Belongs to the CinA family%3B KEGG: bli:BL05163 nicotinamide-nucleotide amidase gene gene1994 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01995 S100027_01996 S100027_01996 S100027_01996 1920353 1921399 + Protein RecA ATP-binding%3B Cytoplasm%3B DNA damage%3B DNA recombination%3B DNA repair%3B DNA-binding%3B Nucleotide-binding%3B SOS response%3B It interacts with LexA causing its activation and leading to its autocatalytic cleavage%3B Belongs to the RecA family gene gene1995 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01996 S100027_01997 S100027_01997 S100027_01997 1921740 1923299 + Ribonuclease Cell membrane%3B Endonuclease%3B Hydrolase%3B Membrane%3B Nuclease%3B RNA-binding%3B Transmembrane%3B Transmembrane helix%3B Endoribonuclease that initiates mRNA decay%3B Belongs to the RNase Y family%3B Contains 1 HD domain%3B Contains 1 KH domain%3B KEGG: bli:BL03655 ribonucrease Y%3B Acting on ester bonds gene gene1996 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01997 S100027_01998 S100027_01998 S100027_01998 1923386 1924183 + uncharacterized protein gene gene1997 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01998 S100027_01999 S100027_01999 S100027_01999 1924385 1924645 + Stage V sporulation protein Cell cycle%3B Cell division%3B Septation%3B Sporulation. gene gene1998 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_01999 S100027_02000 S100027_02000 dpeP dpeP 1924750 1925670 + Membrane dipeptidase Belongs to the peptidase M19 family%3B KEGG: blh:BaLi_c19560 membrane dipeptidase gene gene1999 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02000 S100027_02001 S100027_02001 S100027_02001 1925798 1926838 + L-threonine 3-dehydrogenase Cytoplasm%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Zinc%3B Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: bli:BL03658 threonine 3-dehydrogenase gene gene2000 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02001 S100027_02002 S100027_02002 gcaT gcaT 1926854 1928029 + Glycine C-acetyltransferase Biotin biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Catalyzes the decarboxylative condensation of pimeloyl- [acyl-carrier protein] and L-alanine to produce 8-amino-7- oxononanoate (AON)%2C [acyl-carrier protein]%2C and carbon dioxide%3B Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily%3B KEGG: bli:BL03659 glycine C-acetyltransferase gene gene2001 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02002 S100027_02003 S100027_02003 miaB miaB 1928173 1929702 + tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase 4Fe-4S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B S-adenosyl-L-methionine%3B Transferase%3B tRNA processing%3B Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A)%2C leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine%3B Belongs to the methylthiotransferase family. MiaB subfamily%3B Contains 1 MTTase N-terminal domain%3B Contains 1 TRAM domain%3B KEGG: bsu:BSU17010 tRNA-2-methylthio-N6-dimethylallyladenosine synthase gene gene2002 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02003 S100027_02004 S100027_02004 S100027_02004 1929704 1930135 + Polar-amino-acid-transporting ATPase May work together with YlbF to regulate community development%3B KEGG: cml:BN424_2091 polar amino acid transport system ATP-binding protein gene gene2003 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02004 S100027_02005 S100027_02005 S100027_02005 1930378 1930926 + Spore coat protein Sporulation%3B Morphogenic protein required for the assembly of the outer coat of the endospore. Is also a regulatory protein for the expression of cotA%2C cotB%2C cotC%2C cotH and other genes encoding spore outer coat proteins%3B Belongs to the CotE family gene gene2004 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02005 S100027_02006 S100027_02006 S100027_02006 1931037 1933646 + DNA mismatch repair protein MutS ATP-binding%3B DNA damage%3B DNA repair%3B DNA-binding%3B Nucleotide-binding%3B This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity%3B Belongs to the DNA mismatch repair MutS family gene gene2005 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02006 S100027_02007 S100027_02007 S100027_02007 1933664 1935574 + DNA mismatch repair protein MutL DNA damage%3B DNA repair%3B This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker'%2C a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex%3B Belongs to the DNA mismatch repair MutL/HexB family gene gene2006 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02007 S100027_02008 S100027_02008 pcaC pcaC 1935909 1936190 + 4-carboxymuconolactone decarboxylase Contains 1 ABM domain%3B KEGG: mme:Marme_0104 4-carboxymuconolactone decarboxylase gene gene2007 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02008 S100027_02009 S100027_02009 S100027_02009 1936372 1936899 + Ribonuclease YxiD Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene2008 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02009 S100027_02010 S100027_02010 S100027_02010 1937159 1937638 + hypothetical protein gene gene2009 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02010 S100027_02011 S100027_02011 S100027_02011 1937718 1937990 + hypothetical protein gene gene2010 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02011 S100027_02012 S100027_02012 S100027_02012 1938142 1939128 - Putative metal chaperone YciC Chaperone%3B GTP-binding%3B Nucleotide-binding%3B Zinc%3B May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc%3B Belongs to the SIMIBI class G3E GTPase family. CobW subfamily%3B Contains 1 cobW C-terminal domain gene gene2011 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02012 S100027_02013 S100027_02013 nuoF nuoF 1939145 1939531 - NADH:ubiquinone reductase (H(+)-translocating) 2Fe-2S%3B Electron transport%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Transport%3B Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions%3B Belongs to the 2Fe2S Shethna-type ferredoxin family%3B KEGG: dmt:DESME_04270 NADH-quinone oxidoreductase subunit F gene gene2012 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02013 S100027_02014 S100027_02014 S100027_02014 1939910 1940404 - Phosphinothricin acetyltransferase Acyltransferase%3B Transferase%3B Plays a role in the resistance against the toxic effects of L-methionine sulfoximine (MSX)%2C a rare amino acid%2C which inhibits glutamine synthetase (GlnA). Catalyzes the acetylation of L-methionine sulfoximine (MSX). It can also use L-methionine sulfone (MSO)%3B Contains 1 N-acetyltransferase domain%3B KEGG: bli:BL00151 phosphinothricin acetyltransferase gene gene2013 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02014 S100027_02015 S100027_02015 S100027_02015 1940617 1941264 - hypothetical protein gene gene2014 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02015 S100027_02016 S100027_02016 S100027_02016 1941539 1941649 - hypothetical protein gene gene2015 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02016 S100027_02017 S100027_02017 aofH aofH 1941880 1943322 + Monoamine oxidase FAD%3B Flavoprotein%3B Oxidoreductase%3B Belongs to the flavin monoamine oxidase family. FIG1 subfamily%3B KEGG: blh:BaLi_c19750 monoamine oxidase gene gene2016 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02017 S100027_02018 S100027_02018 S100027_02018 1943771 1944448 + UPF0700 transmembrane protein YoaK Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0700 family gene gene2017 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02018 S100027_02019 S100027_02019 S100027_02019 1944584 1946053 + K(+)/H(+) antiporter NhaP2 Antiport%3B Cell inner membrane%3B Cell membrane%3B Ion transport%3B Membrane%3B Potassium%3B Potassium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels%3B Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2. A. 36) family. NhaP2 subfamily%3B Contains 1 RCK C-terminal domain gene gene2018 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02019 S100027_02020 S100027_02020 S100027_02020 1946361 1946924 + Tetracycline resistance protein Antibiotic resistance%3B Antiport%3B Cell membrane%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter. Belongs to the major facilitator superfamily. TCR/Tet family%3B overlaps another CDS with the same product name gene gene2019 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02020 S100027_02021 S100027_02021 S100027_02021 1946890 1947735 + Tetracycline resistance protein Antibiotic resistance%3B Antiport%3B Cell membrane%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Plasmid%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter. Belongs to the major facilitator superfamily. TCR/Tet family%3B overlaps another CDS with the same product name gene gene2020 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02021 S100027_02022 S100027_02022 menH menH 1947849 1948715 + 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate synthase Hydrolase%3B Belongs to the AB hydrolase superfamily%3B KEGG: vir:X953_13270 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate synthase gene gene2021 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02022 S100027_02023 S100027_02023 S100027_02023 1949283 1949594 + UPF0145 protein Belongs to the UPF0145 family gene gene2022 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02023 S100027_02024 S100027_02024 S100027_02024 1949643 1950293 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2023 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02024 S100027_02025 S100027_02025 S100027_02025 1950327 1951343 - Serine-type D-Ala-D-Ala carboxypeptidase Antibiotic resistance%3B Cell membrane%3B Cell wall biogenesis/degradation%3B Membrane%3B Signal%3B Affects the methicillin resistance level and autolysis in the presence of Triton X-100 as well as the cell wall structure but its precise function is unknown%3B KEGG: msm:MSMEG_4455 D-alanyl-D-alanine carboxypeptidase gene gene2024 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02025 S100027_02026 S100027_02026 S100027_02026 1951799 1952989 + Demethyllactenocin mycarosyltransferase Antibiotic biosynthesis%3B Transferase%3B Involved in the biosynthesis of mycarose which is a 6- deoxyhexose sugar required during production of the macrolide antibiotic tylosin. Catalyzes the transfer of L-mycarosyl from dTDP-beta-L-mycarose to demethyllactenocin to yield demethylmacrocin%3B Belongs to the UDP-glycosyltransferase family%3B KEGG: sma:SAV_945 dTDP-L-oleandrosyltransferase%3B Hexosyltransferases gene gene2025 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02026 S100027_02027 S100027_02027 S100027_02027 1953115 1954692 + Aspartate-proton symporter Amino-acid transport%3B Cell membrane%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Uptake of L-aspartate with the concomitant import of a proton. Can also transport aspartate hydroxamate and L-glutamate with lower affinity and efficiency. Belongs to the amino acid-polyamine-organocation (APC) superfamily. AGT (TC 2. A. 3. 11) family gene gene2026 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02027 S100027_02028 S100027_02028 S100027_02028 1954740 1955039 - Spore coat protein F-like protein YraD Sporulation%3B Belongs to the CotF family gene gene2027 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02028 S100027_02029 S100027_02029 S100027_02029 1955036 1955236 - uncharacterized protein gene gene2028 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02029 S100027_02030 S100027_02030 S100027_02030 1955348 1956616 - N-acetylmuramoyl-L-alanine amidase Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Polysaccharide degradation%3B Repeat%3B Sporulation%3B Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily%3B Contains 2 LysM repeats%3B KEGG: mta:Moth_0054 N-acetylmuramoyl-L-alanine amidase gene gene2029 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02030 S100027_02031 S100027_02031 S100027_02031 1956790 1957374 + putative HTH-type transcriptional regulator YezE DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH tetR-type DNA-binding domain gene gene2030 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02031 S100027_02032 S100027_02032 S100027_02032 1957462 1957881 + uncharacterized protein Belongs to the limonene-1%2C2-epoxide hydrolase family gene gene2031 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02032 S100027_02033 S100027_02033 S100027_02033 1957902 1958747 + NAD(P)H dehydrogenase (quinone) Oxidoreductase%3B Belongs to the NmrA-type oxidoreductase family%3B KEGG: sxi:SXIM_50260 NAD(P)H dehydrogenase (quinone) gene gene2032 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02033 S100027_02034 S100027_02034 S100027_02034 1958802 1959107 - hypothetical protein gene gene2033 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02034 S100027_02035 S100027_02035 S100027_02035 1959265 1959720 + uncharacterized protein Belongs to the OsmC/Ohr family gene gene2034 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02035 S100027_02036 S100027_02036 S100027_02036 1959717 1960076 - Multidrug resistance protein EbrB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of a multidrug efflux pump. Confers resistance to cationic lipophilic dyes such as ethidium bromide%2C acriflavine%2C pyronine Y and safranin O. The efflux is probably coupled to an influx of protons%3B Belongs to the small multidrug resistance (SMR) protein family. EbrA/EbrB (TC 2. A. 7. 1. 6) subfamily gene gene2035 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02036 S100027_02037 S100027_02037 S100027_02037 1960090 1960407 - Multidrug resistance protein EbrA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of a multidrug efflux pump. Confers resistance to cationic lipophilic dyes such as ethidium bromide%2C acriflavine%2C pyronine Y and safranin O. The efflux is probably coupled to an influx of protons (By similarity)%3B Belongs to the small multidrug resistance (SMR) protein family. EbrA/EbrB (TC 2. A. 7. 1. 6) subfamily gene gene2036 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02037 S100027_02038 S100027_02038 S100027_02038 1960815 1961036 - hypothetical protein gene gene2037 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02038 S100027_02039 S100027_02039 S100027_02039 1961162 1961563 + uncharacterized protein gene gene2038 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02039 S100027_02040 S100027_02040 miaA miaA 1961665 1962609 + tRNA dimethylallyltransferase ATP-binding%3B Magnesium%3B Nucleotide-binding%3B Transferase%3B tRNA processing%3B Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine%2C leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)%3B Belongs to the IPP transferase family%3B KEGG: bli:BL05174 tRNA dimethylallyltransferase gene gene2039 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02040 S100027_02041 S100027_02041 S100027_02041 1962651 1962872 + RNA-binding protein Hfq RNA-binding%3B Stress response%3B RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress%2C environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs%3B Belongs to the Hfq family gene gene2040 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02041 S100027_02042 S100027_02042 S100027_02042 1963163 1963375 + uncharacterized protein gene gene2041 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02042 S100027_02043 S100027_02043 S100027_02043 1963622 1964020 + Protein NrdI Probably involved in ribonucleotide reductase function%3B Belongs to the NrdI family gene gene2042 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02043 S100027_02044 S100027_02044 S100027_02044 1963977 1966079 + Ribonucleoside-diphosphate reductase Allosteric enzyme%3B ATP-binding%3B Disulfide bond%3B DNA replication%3B Nucleotide-binding%3B Oxidoreductase%3B Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase large chain family%3B KEGG: bsu:BSU17380 ribonucleoside-diphosphate reductase alpha chain%3B overlaps another CDS with the same product name gene gene2043 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02044 S100027_02045 S100027_02045 S100027_02045 1966067 1967077 + Ribonucleoside-diphosphate reductase DNA replication%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase small chain family%3B KEGG: bsu:BSU17390 ribonucleoside-diphosphate reductase beta chain%3B overlaps another CDS with the same product name gene gene2044 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02045 S100027_02046 S100027_02046 S100027_02046 1967191 1967808 + uncharacterized protein gene gene2045 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02046 S100027_02047 S100027_02047 S100027_02047 1967693 1968394 - hypothetical protein gene gene2046 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02047 S100027_02048 S100027_02048 S100027_02048 1968379 1968606 - hypothetical protein gene gene2047 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02048 S100027_02049 S100027_02049 S100027_02049 1968820 1969251 + Iron-sulfur cluster assembly scaffold protein IscU Metal-binding%3B Zinc%3B A scaffold on which IscS assembles Fe-S clusters. Subsequently gives the nascent cluster to other proteins. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters (By similarity)%3B Belongs to the NifU family gene gene2048 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02049 S100027_02050 S100027_02050 S100027_02050 1969378 1969857 + Peroxide-responsive repressor PerR Cytoplasm%3B DNA-binding%3B Manganese%3B Metal-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Zinc%3B Manganese-dependent repressor that controls a regulon of oxidative stress resistance and iron-storage proteins. May act as a hydrogen peroxide and organic hydroperoxide sensor (By similarity)%3B Belongs to the Fur family gene gene2049 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02050 S100027_02051 S100027_02051 S100027_02051 1969854 1970519 + HTH-type transcriptional regulator McbR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Important for biofilm formation. Represses expression of McbA by binding to its promoter region%2C which prevents colanic acid overproduction and mucoidy%3B Contains 1 HTH gntR-type DNA-binding domain gene gene2050 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02051 S100027_02052 S100027_02052 S100027_02052 1970527 1971495 + putative 42.1 kDa protein in intracellular alkaline protease 3'region gene gene2051 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02052 S100027_02053 S100027_02053 S100027_02053 1971550 1972311 - N-acetylmuramoyl-L-alanine amidase Cell wall%3B Cell wall biogenesis/degradation%3B Competence%3B Hydrolase%3B Metal-binding%3B Repeat%3B Secreted%3B Sporulation%3B Zinc%3B Autolysins are involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella - in particular of its basal body - and sporulation. CwlC is able to hydrolyze type A cell walls such as B. subtilis. Its main function is to lyze the mother cell wall peptidoglycan%2C playing a role during sporulation%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B Contains 1 SPOR domain%3B KEGG: bsu:BSU17410 N-acetylmuramoyl-L-alanine amidase gene gene2052 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02053 S100027_02054 S100027_02054 S100027_02054 1972844 1973326 - hypothetical protein gene gene2053 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02054 S100027_02055 S100027_02055 S100027_02055 1973349 1973801 - hypothetical protein gene gene2054 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02055 S100027_02056 S100027_02056 S100027_02056 1973901 1974146 - hypothetical protein gene gene2055 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02056 S100027_02057 S100027_02057 S100027_02057 1974329 1974532 + Repressor rok Coiled coil%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation. gene gene2056 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02057 S100027_02058 S100027_02058 S100027_02058 1974746 1975369 + HTH-type transcriptional repressor KstR2 DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Controls the expression of a small regulon that may play a role in the utilization of cholesterol%3B Contains 1 HTH tetR-type DNA-binding domain gene gene2057 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02058 S100027_02059 S100027_02059 S100027_02059 1975372 1975758 + hypothetical protein gene gene2058 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02059 S100027_02060 S100027_02060 S100027_02060 1975791 1977140 + Cytosine permease Cell inner membrane%3B Cell membrane%3B Cytosine metabolism%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Required for cytosine transport into the cell. Belongs to the purine-cytosine permease (2. A. 39) family gene gene2059 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02060 S100027_02061 S100027_02061 S100027_02061 1977165 1979270 + N-methylhydantoinase (ATP-hydrolyzing) ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Catalyzes the carboxylation of acetophenone to form 3- oxo-3-phenylpropanoate (benzoylacetate) in the anaerobic catabolism of ethylbenzene. Also carboxylates propiophenone at the same rate and 4-acetyl-pyridine at lower rates%3B Belongs to the oxoprolinase family%3B KEGG: bld:BLi01982 N-methylhydantoinase A%3B overlaps another CDS with the same product name gene gene2060 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02061 S100027_02062 S100027_02062 S100027_02062 1979267 1980745 + N-methylhydantoinase (ATP-hydrolyzing) ATP-binding%3B Cytoplasm%3B Hydrolase%3B Nucleotide-binding%3B Catalyzes the cleavage of 5-oxo-L-proline to form L- glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. Acts in the glutathione degradation pathway%3B Belongs to the oxoprolinase family%3B KEGG: baci:B1NLA3E_09215 N-methylhydantoinase B%3B overlaps another CDS with the same product name gene gene2061 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02062 S100027_02063 S100027_02063 S100027_02063 1980742 1982481 + N-methylhydantoinase (ATP-hydrolyzing) ATP-binding%3B Hydrolase%3B Nucleotide-binding%3B Phosphoprotein%3B Catalyzes the cleavage of 5-oxo-L-proline to form L- glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. Belongs to the oxoprolinase family%3B KEGG: bli:BL00460 N-methylhydantoinase B%3B overlaps another CDS with the same product name gene gene2062 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02063 S100027_02064 S100027_02064 S100027_02064 1982654 1983088 + hypothetical protein gene gene2063 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02064 S100027_02065 S100027_02065 S100027_02065 1983381 1983557 + hypothetical protein gene gene2064 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02065 S100027_02066 S100027_02066 S100027_02066 1983765 1983971 + uncharacterized protein gene gene2065 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02066 S100027_02067 S100027_02067 S100027_02067 1984034 1984324 + uncharacterized protein gene gene2066 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02067 S100027_02068 S100027_02068 S100027_02068 1984483 1986435 + Ribonuclease YxiD Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene2067 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02068 S100027_02069 S100027_02069 S100027_02069 1986469 1986924 + hypothetical protein gene gene2068 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02069 S100027_02070 S100027_02070 S100027_02070 1987337 1987528 + hypothetical protein gene gene2069 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02070 S100027_02071 S100027_02071 S100027_02071 1988098 1988796 + hypothetical protein gene gene2070 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02071 S100027_02072 S100027_02072 S100027_02072 1989211 1990176 + Stage V sporulation protein ATP-binding%3B Nucleotide-binding%3B Sporulation%3B Belongs to the cbxX/cfxQ family gene gene2071 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02072 S100027_02073 S100027_02073 S100027_02073 1990280 1991542 + GTPase HflX Cytoplasm%3B GTP-binding%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis%3B Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family%3B Contains 1 Hflx-type G (guanine nucleotide-binding) domain gene gene2072 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02073 S100027_02074 S100027_02074 S100027_02074 1991561 1992826 + Cystathionine gamma-lyase KEGG: ava:Ava_4213 cystathionine gamma-lyase gene gene2073 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02074 S100027_02075 S100027_02075 S100027_02075 1992929 1993336 + HTH-type transcriptional regulator GlnR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Represses many genes including the glnRA operon and tnrA during growth with nitrogen excess%3B Contains 1 HTH merR-type DNA-binding domain gene gene2074 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02075 S100027_02076 S100027_02076 glnA glnA 1993393 1994727 + Glutamate--ammonia ligase ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Phosphoprotein%3B Belongs to the glutamine synthetase family%3B KEGG: bsu:BSU17460 glutamine synthetase gene gene2075 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02076 S100027_02077 S100027_02077 S100027_02077 1995058 1995261 + hypothetical protein gene gene2076 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02077 S100027_02078 S100027_02078 S100027_02078 1995343 1995510 - hypothetical protein gene gene2077 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02078 S100027_02079 S100027_02079 S100027_02079 1996363 1996830 + hypothetical protein gene gene2078 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02079 S100027_02080 S100027_02080 S100027_02080 1996832 1998268 + hypothetical protein gene gene2079 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02080 S100027_02081 S100027_02081 S100027_02081 1998395 1998712 - hypothetical protein gene gene2080 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02081 S100027_02082 S100027_02082 S100027_02082 1999652 2000068 + hypothetical protein gene gene2081 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02082 S100027_02083 S100027_02083 S100027_02083 2000136 2000438 + hypothetical protein gene gene2082 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02083 S100027_02084 S100027_02084 S100027_02084 2000673 2001647 + uncharacterized protein gene gene2083 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02084 S100027_02085 S100027_02085 S100027_02085 2001714 2001956 + hypothetical protein gene gene2084 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02085 S100027_02086 S100027_02086 S100027_02086 2002009 2002488 + hypothetical protein gene gene2085 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02086 S100027_02087 S100027_02087 tehB tehB 2002630 2003226 + Tellurite methyltransferase KEGG: pmu:PM0656 tellurite methyltransferase gene gene2086 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02087 S100027_02088 S100027_02088 S100027_02088 2003332 2003811 + uncharacterized protein Signal. gene gene2087 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02088 S100027_02089 S100027_02089 S100027_02089 2003845 2004420 + hypothetical protein gene gene2088 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02089 S100027_02090 S100027_02090 S100027_02090 2004581 2005057 + Repressor rok Coiled coil%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation. gene gene2089 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02090 S100027_02091 S100027_02091 S100027_02091 2005116 2005349 + hypothetical protein gene gene2090 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02091 S100027_02092 S100027_02092 S100027_02092 2005698 2006318 - hypothetical protein gene gene2091 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02092 S100027_02093 S100027_02093 S100027_02093 2007029 2007613 + putative HTH-type transcriptional regulator YvdT DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH tetR-type DNA-binding domain gene gene2092 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02093 S100027_02094 S100027_02094 S100027_02094 2007694 2008029 + putative membrane protein YvdS Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the small multidrug resistance (SMR) protein family gene gene2093 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02094 S100027_02095 S100027_02095 S100027_02095 2008026 2008346 + Spermidine export protein MdtJ Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Catalyzes the excretion of spermidine%3B Belongs to the small multidrug resistance (SMR) protein family. MdtJ subfamily gene gene2094 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02095 S100027_02096 S100027_02096 speG speG 2008375 2008629 + Diamine N-acetyltransferase Acyltransferase%3B Cytoplasm%3B Magnesium%3B Metal-binding%3B Transferase%3B Involved in the protection against polyamine toxicity by regulating their concentration. Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to the primary amino groups of spermidine to yield N(1)- and N(8)-acetylspermidine%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: van:VAA_01303 diamine N-acetyltransferase%3B overlaps another CDS with the same product name gene gene2095 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02096 S100027_02097 S100027_02097 S100027_02097 2008598 2008906 + Diamine N-acetyltransferase Acyltransferase%3B Cytoplasm%3B Magnesium%3B Metal-binding%3B Plasmid%3B Transferase%3B Involved in the protection against polyamine toxicity by regulating their concentration. Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to the primary amino groups of spermidine to yield N(1)- and N(8)-acetylspermidine%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: mrs:Murru_0006 diamine N-acetyltransferase%3B overlaps another CDS with the same product name gene gene2096 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02097 S100027_02098 S100027_02098 S100027_02098 2008944 2009300 - hypothetical protein gene gene2097 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02098 S100027_02099 S100027_02099 S100027_02099 2009483 2009917 + uncharacterized protein Signal. gene gene2098 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02099 S100027_02100 S100027_02100 S100027_02100 2010251 2010460 + Thiol-disulfide oxidoreductase ResA Cell membrane%3B Cytochrome c-type biogenesis%3B Disulfide bond%3B Membrane%3B Oxidoreductase%3B Redox-active center%3B Signal-anchor%3B Transmembrane%3B Transmembrane helix%3B Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA%2C leading to breakage of disulfide bonds in apocytochrome%3B following this reduction heme can be covalently attached%3B Belongs to the thioredoxin family. ResA subfamily%3B Contains 1 thioredoxin domain gene gene2099 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02100 S100027_02101 S100027_02101 S100027_02101 2010609 2011472 + uncharacterized protein Belongs to the manganese catalase family gene gene2100 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02101 S100027_02102 S100027_02102 S100027_02102 2011557 2012357 + hypothetical protein gene gene2101 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02102 S100027_02103 S100027_02103 S100027_02103 2012489 2013007 + Ribosomal-protein-alanine N-acetyltransferase Acyltransferase%3B Transferase%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bce:BC2051 ribosomal-protein-alanine N-acetyltransferase gene gene2102 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02103 S100027_02104 S100027_02104 S100027_02104 2013000 2013302 + hypothetical protein gene gene2103 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02104 S100027_02105 S100027_02105 S100027_02105 2013621 2014217 + putative HTH-type transcriptional regulator YuxN DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH tetR-type DNA-binding domain gene gene2104 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02105 S100027_02106 S100027_02106 S100027_02106 2014430 2014885 + HTH-type transcriptional regulator MhqR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Negatively regulates mhqA%2C mhqED%2C mhqNOP%2C and azoR2 which may contribute to the degradation of aromatic compounds%3B Contains 1 HTH marR-type DNA-binding domain gene gene2105 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02106 S100027_02107 S100027_02107 S100027_02107 2014958 2015347 + Putative NAD(P)H nitroreductase YdgI Flavoprotein%3B FMN%3B NAD%3B NADP%3B Oxidoreductase%3B Belongs to the nitroreductase family%3B KEGG: bsr:I33_0620 putative NAD(P)H nitroreductase%3B Oxidoreductases gene gene2106 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02107 S100027_02108 S100027_02108 S100027_02108 2015445 2016383 + Putative ring-cleaving dioxygenase MhqO Aromatic hydrocarbons catabolism%3B Cytoplasm%3B Detoxification%3B Dioxygenase%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Putative ring-cleavage dioxygenase that may contribute to the degradation of aromatic compounds%3B Belongs to the extradiol ring-cleavage dioxygenase family gene gene2107 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02108 S100027_02109 S100027_02109 S100027_02109 2016405 2017013 + uncharacterized protein Flavoprotein%3B FMN%3B Belongs to the flavoredoxin family gene gene2108 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02109 S100027_02110 S100027_02110 S100027_02110 2017213 2017824 + NAD(P)H dehydrogenase (quinone) Flavoprotein%3B FMN%3B NAD%3B NADP%3B Nucleotide-binding%3B Oxidoreductase%3B It seems to function in response to environmental stress when various electron transfer chains are affected or when the environment is highly oxidizing. It reduces quinones to the hydroquinone state to prevent interaction of the semiquinone with O2 and production of superoxide (By similarity)%3B Belongs to the WrbA family%3B Contains 1 flavodoxin-like domain%3B KEGG: bli:BL02638 NAD(P)H dehydrogenase (quinone) gene gene2109 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02110 S100027_02111 S100027_02111 S100027_02111 2018278 2019111 + hypothetical protein gene gene2110 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02111 S100027_02112 S100027_02112 S100027_02112 2019205 2019963 + hypothetical protein gene gene2111 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02112 S100027_02113 S100027_02113 thyA thyA 2020023 2020862 + Thymidylate synthase Cytoplasm%3B Methyltransferase%3B Nucleotide biosynthesis%3B Transferase%3B Provides the sole de novo source of dTMP for DNA biosynthesis%3B Belongs to the thymidylate synthase family. Bacterial- type ThyA subfamily%3B KEGG: bli:BL02642 thymidylate synthase gene gene2112 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02113 S100027_02114 S100027_02114 S100027_02114 2021221 2021649 + Sporulation-specific extracellular nuclease Hydrolase%3B Manganese%3B Nuclease%3B Secreted%3B Signal%3B Sporulation%3B Degrades both double-stranded linear and covalently closed circular DNA. Likely to play a scavenging role in order to supply nutrients under starvation conditions. To B. subtilis NucA/ComI gene gene2113 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02114 S100027_02115 S100027_02115 S100027_02115 2021845 2022468 - Repressor LexA Autocatalytic cleavage%3B DNA damage%3B DNA repair%3B DNA replication%3B DNA-binding%3B Hydrolase%3B Repressor%3B SOS response%3B Transcription%3B Transcription regulation%3B Represses a number of genes involved in the response to DNA damage (SOS response)%2C including recA and lexA. In the presence of single-stranded DNA%2C RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA%2C leading to derepression of the SOS regulon and eventually DNA repair%3B Belongs to the peptidase S24 family%3B KEGG: pae:PA3007 repressor LexA gene gene2114 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02115 S100027_02116 S100027_02116 S100027_02116 2022615 2022932 + Cell division suppressor protein YneA Cell cycle%3B Cell division%3B Cytoplasm%3B DNA damage%3B DNA repair%3B Septation%3B SOS response%3B Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly%2C after the assembly of the Z ring%2C by probably suppressing recruitment of FtsL and/or DivIC to the division machinery%3B Belongs to the YneA family gene gene2115 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02116 S100027_02117 S100027_02117 S100027_02117 2022951 2023598 + Resolvase like protein YneB Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene2116 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02117 S100027_02118 S100027_02118 S100027_02118 2023664 2023897 + 5-formyltetrahydrofolate cyclo-ligase Cytoplasm%3B Belongs to the UPF0291 family%3B KEGG: rum:CK1_06990 5-formyltetrahydrofolate cyclo-ligase gene gene2117 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02118 S100027_02119 S100027_02119 S100027_02119 2024064 2026067 + Transketolase Calcium%3B Magnesium%3B Metal-binding%3B Thiamine pyrophosphate%3B Transferase%3B Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor%2C via a covalent intermediate with the cofactor thiamine pyrophosphate%3B Belongs to the transketolase family%3B KEGG: bsu:BSU17890 transketolase gene gene2118 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02119 S100027_02120 S100027_02120 S100027_02120 2026222 2026659 + Sporulation inhibitor of replication protein SirA DNA replication inhibitor%3B Sporulation%3B Inhibits DNA replication in growing cells%2C thus reducing chromosome copy number and playing a significant role during the onset of sporulation gene gene2119 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02120 S100027_02121 S100027_02121 S100027_02121 2026744 2026962 + UPF0154 protein Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0154 family gene gene2120 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02121 S100027_02122 S100027_02122 S100027_02122 2027043 2027204 - Aspartyl-phosphate phosphatase YnzD Hydrolase%3B Sporulation%3B Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation%3B Belongs to the spo0E family gene gene2121 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02122 S100027_02123 S100027_02123 S100027_02123 2027447 2028154 + Cytochrome c-type bioproteinis protein CcdA Cell membrane%3B Cytochrome c-type biogenesis%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane%2C promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat%3B Cytochrome c oxidase activity is partially restored by mutations in bdbC or bdbD that are defective in the synthesis of disulfide bond containing proteins. The same mutations abrogate the need for CcdA in sporulation%3B Belongs to the DsbD family gene gene2122 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02123 S100027_02124 S100027_02124 S100027_02124 2028236 2028607 + Protein CcdB Phosphoprotein%3B Two-component regulatory system%3B Contains 1 response regulatory domain gene gene2123 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02124 S100027_02125 S100027_02125 S100027_02125 2028690 2029175 + Protein CcdC Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2124 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02125 S100027_02126 S100027_02126 S100027_02126 2029211 2029639 - uncharacterized protein gene gene2125 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02126 S100027_02127 S100027_02127 S100027_02127 2029844 2030251 - Spore coat protein Sporulation. gene gene2126 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02127 S100027_02128 S100027_02128 acnA acnA 2030956 2033682 + Aconitate hydratase Amino-acid biosynthesis%3B Iron%3B Iron-sulfur%3B Lyase%3B Lysine biosynthesis%3B Metal-binding%3B RNA-binding%3B Tricarboxylic acid cycle%3B Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate. Also able to catalyze the hydration of cis-homoaconitate to yield (R)-homocitrate%2C but with a lower efficiency (PubMed:23106124). Could catalyze the hydration of 2- methyl-cis-aconitate to yield (2R%2C3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein (By similarity)%3B Belongs to the aconitase/IPM isomerase family%3B KEGG: bli:BL02940 aconitate hydratase gene gene2127 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02128 S100027_02129 S100027_02129 S100027_02129 2033754 2034260 + Thiol-disulfide oxidoreductase ResA Cell membrane%3B Cytochrome c-type biogenesis%3B Disulfide bond%3B Membrane%3B Oxidoreductase%3B Redox-active center%3B Signal-anchor%3B Transmembrane%3B Transmembrane helix%3B Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA%2C leading to breakage of disulfide bonds in apocytochrome%3B following this reduction heme can be covalently attached. Does not play a role in sporulation%3B Belongs to the thioredoxin family. ResA subfamily%3B Contains 1 thioredoxin domain gene gene2128 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02129 S100027_02130 S100027_02130 S100027_02130 2034332 2034457 + uncharacterized protein gene gene2129 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02130 S100027_02131 S100027_02131 S100027_02131 2034526 2034669 + Small%2C acid-soluble spore protein Sporulation%3B Belongs to the SspN family gene gene2130 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02131 S100027_02132 S100027_02132 S100027_02132 2034695 2034931 + Small%2C acid-soluble spore protein Tlp Sporulation%3B Belongs to the Tlp family gene gene2131 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02132 S100027_02133 S100027_02133 ybgC ybgC 2035038 2035454 + Putative acyl-CoA thioesterase YneP Hydrolase%3B Has acyl-CoA thioesterase activity%3B Belongs to the 4-hydroxybenzoyl-CoA thioesterase family%3B KEGG: bsr:I33_2017 acyl-CoA thioester hydrolase%3B Thiolester hydrolases gene gene2132 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02133 S100027_02134 S100027_02134 S100027_02134 2035454 2035756 + NAD(+) synthase KEGG: ble:BleG1_2142 NAD+ synthase gene gene2133 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02134 S100027_02135 S100027_02135 S100027_02135 2035988 2036350 - hypothetical protein gene gene2134 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02135 S100027_02136 S100027_02136 S100027_02136 2036695 2037726 - hypothetical protein gene gene2135 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02136 S100027_02137 S100027_02137 S100027_02137 2038050 2038337 - uncharacterized protein Belongs to the HesB/IscA family gene gene2136 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02137 S100027_02138 S100027_02138 plsY plsY 2038440 2039033 - Glycerol-3-phosphate 1-O-acyltransferase Cell membrane%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor%2C but not acyl-CoA or acyl-ACP%3B Belongs to the PlsY family%3B KEGG: bli:BL02954 glycerol-3-phosphate acyltransferase PlsY gene gene2137 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02138 S100027_02139 S100027_02139 S100027_02139 2039212 2039625 + uncharacterized protein gene gene2138 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02139 S100027_02140 S100027_02140 parE parE 2039943 2041916 + DNA topoisomerase 4 subunit ATP-binding%3B DNA-binding%3B Isomerase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Topoisomerase%3B Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule%3B Belongs to the type II topoisomerase family. ParE type 2 subfamily%3B Contains 1 Toprim domain%3B KEGG: bli:BL01186 topoisomerase IV subunit B%3B Other isomerases gene gene2139 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02140 S100027_02141 S100027_02141 parC parC 2041921 2044344 + DNA topoisomerase 4 subunit Cell membrane%3B Cytoplasm%3B DNA-binding%3B Isomerase%3B Membrane%3B Topoisomerase%3B Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule%3B Belongs to the topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily%3B KEGG: bsu:BSU18100 topoisomerase IV subunit A%3B Other isomerases gene gene2140 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02141 S100027_02142 S100027_02142 S100027_02142 2044646 2045737 - Arabinose metabolism transcriptional repressor Cytoplasm%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcriptional repressor of the arabinose utilization genes%3B Contains 1 HTH gntR-type DNA-binding domain gene gene2141 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02142 S100027_02143 S100027_02143 araB araB 2046090 2047697 + Ribulokinase KEGG: lme:LEUM_0854 L-ribulokinase gene gene2142 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02143 S100027_02144 S100027_02144 araD araD 2047711 2048406 + L-ribulose-5-phosphate 4-epimerase Isomerase%3B Metal-binding%3B Zinc%3B Catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate. Is involved in the anaerobic L-ascorbate utilization (By similarity)%3B Belongs to the aldolase class II family. AraD/FucA subfamily%3B KEGG: ype:YPO2230 L-ribulose-5-phosphate 4-epimerase gene gene2143 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02144 S100027_02145 S100027_02145 araA araA 2048462 2049886 + L-arabinose isomerase Arabinose catabolism%3B Carbohydrate metabolism%3B Isomerase%3B Manganese%3B Metal-binding%3B Catalyzes the conversion of L-arabinose to L-ribulose%3B Belongs to the arabinose isomerase family%3B KEGG: bli:BL01182 L-arabinose isomerase gene gene2144 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02145 S100027_02146 S100027_02146 S100027_02146 2050170 2051564 + D-xylose-proton symporter Cell membrane%3B Membrane%3B Sugar transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Uptake of D-xylose across the boundary membrane with the concomitant transport of protons into the cell (symport system)%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene2145 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02146 S100027_02147 S100027_02147 S100027_02147 2052135 2052917 - 3-oxoacyl-[acyl-carrier-protein] reductase Cytoplasm%3B NAD%3B Oxidoreductase%3B Stress response%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: ppb:PPUBIRD1_2441 3-oxoacyl-(acyl-carrier protein) reductase gene gene2146 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02147 S100027_02148 S100027_02148 S100027_02148 2053241 2053366 - hypothetical protein gene gene2147 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02148 S100027_02149 S100027_02149 S100027_02149 2053395 2053739 - hypothetical protein gene gene2148 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02149 S100027_02150 S100027_02150 S100027_02150 2054067 2055479 + Amino-acid carrier protein AlsT Amino-acid transport%3B Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the sodium:alanine (SAF) symporter family gene gene2149 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02150 S100027_02151 S100027_02151 S100027_02151 2055524 2055868 - hypothetical protein gene gene2150 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02151 S100027_02152 S100027_02152 narI narI 2055981 2056667 - Nitrate reductase Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Nitrate assimilation%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B KEGG: bli:BL01175 nitrate reductase gamma subunit gene gene2151 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02152 S100027_02153 S100027_02153 S100027_02153 2056664 2057206 - putative nitrate reductase molybdenum cofactor assembly chaperone NarJ Chaperone%3B Cytoplasm%3B Nitrate assimilation%3B Chaperone required for proper molybdenum cofactor insertion and final assembly of the membrane-bound respiratory nitrate reductase%3B Belongs to the NarJ/NarW family gene gene2152 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02153 S100027_02154 S100027_02154 narH narH 2057225 2058694 - Nitrate reductase 3Fe-4S%3B 4Fe-4S%3B Cell membrane%3B Electron transport%3B Iron%3B Iron-sulfur%3B Membrane%3B Metal-binding%3B Nitrate assimilation%3B Oxidoreductase%3B Repeat%3B Transport%3B Contains 3 4Fe-4S ferredoxin-type domains%3B KEGG: sod:Sant_0172 nitrate reductase beta subunit%3B overlaps another CDS with the same product name gene gene2153 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02154 S100027_02155 S100027_02155 narG narG 2058684 2062370 - Nitrate reductase 4Fe-4S%3B Cell membrane%3B Electron transport%3B Iron%3B Iron-sulfur%3B Membrane%3B Metal-binding%3B Molybdenum%3B Nitrate assimilation%3B Oxidoreductase%3B Transport%3B The alpha chain is the actual site of nitrate reduction. Belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: bsu:BSU37280 nitrate reductase alpha subunit%3B overlaps another CDS with the same product name gene gene2154 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02155 S100027_02156 S100027_02156 S100027_02156 2062545 2063786 - hypothetical protein gene gene2155 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02156 S100027_02157 S100027_02157 S100027_02157 2063783 2064025 - hypothetical protein gene gene2156 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02157 S100027_02158 S100027_02158 S100027_02158 2064114 2065217 - Coenzyme PQQ synthesis protein 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B PQQ biosynthesis%3B S-adenosyl-L-methionine%3B Belongs to the radical SAM superfamily. PqqE family gene gene2157 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02158 S100027_02159 S100027_02159 S100027_02159 2065332 2065799 - putative transcription regulator ArfM Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Activates%2C in anaerobic conditions%2C the transcription of the fermentative operons lctEP and alsDS%2C of the hmp gene encoding a flavohemoglobin-like protein%2C the nitrite reductase operon nasDE and the heme biosynthesis genes hemN and hemZ gene gene2158 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02159 S100027_02160 S100027_02160 S100027_02160 2065949 2066671 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B To H. influenzae HI_1626 gene gene2159 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02160 S100027_02161 S100027_02161 S100027_02161 2066717 2067430 - Anaerobic regulatory protein 4Fe-4S%3B Activator%3B Cytoplasm%3B DNA-binding%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Transcription%3B Transcription regulation%3B It is involved in the activation of genes necessary for anaerobic respiration. Contains 1 cyclic nucleotide-binding domain%3B Contains 1 HTH crp-type DNA-binding domain gene gene2160 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02161 S100027_02162 S100027_02162 S100027_02162 2067576 2068760 - Nitrite extrusion protein Cell membrane%3B Membrane%3B Nitrate assimilation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in excretion of nitrite produced by the dissimilatory reduction of nitrate. Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2. A. 1. 8) family gene gene2161 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02162 S100027_02163 S100027_02163 S100027_02163 2068982 2069221 + hypothetical protein gene gene2162 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02163 S100027_02164 S100027_02164 S100027_02164 2069184 2069933 + CRP-like cAMP-activated global transcriptional regulator Activator%3B cAMP%3B cAMP-binding%3B DNA-binding%3B Kinase%3B Nucleotide-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Transferase%3B Global transcriptional regulator that complexes with cAMP and binds to specific DNA promoter sites%2C causing DNA- bending%2C to regulate transcription. cAMP improves binding to specific DNA sequences%2C probably by altering protein conformation. Involved in the regulation of gntP and gntK genes%2C which are involved in gluconate metabolism (PubMed:16385030). May form dimers which bind to the aceB promoter region in the presence of cAMP and repress the glyoxylate bypass genes (PubMed:15150232). It could be a positive regulator of rpf2 gene expression during growth on acetate as the sole carbon source%2C however because the cytosolic cAMP level is elevated in the presence of glucose and low upon growth on acetate%2C it is conceivable that it is unable to function as an activator under acetate conditions (PubMed:18355281)%3B Contains 1 cyclic nucleotide-binding domain%3B Contains 1 HTH crp-type DNA-binding domain gene gene2163 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02164 S100027_02165 S100027_02165 norB norB 2070090 2072444 + Nitric-oxide reductase (cytochrome c) Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Respiratory chain%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Component of the anaerobic respiratory chain that transforms nitrate to dinitrogen (denitrification). NorB is the catalytic subunit of the enzyme complex. Shows proton pump activity across the membrane in denitrifying bacterial cells. The mononitrogen reduction is probably coupled to electron transport phosphorylation (By similarity)%3B Belongs to the heme-copper respiratory oxidase family%3B KEGG: bli:BL01473 nitric oxide reductase subunit B gene gene2164 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02165 S100027_02166 S100027_02166 S100027_02166 2072489 2073202 - Iron-sulfur cluster repair protein YtfE Cytoplasm%3B Iron%3B Metal-binding%3B Stress response%3B Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions%3B Belongs to the RIC family. YtfE subfamily gene gene2165 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02166 S100027_02167 S100027_02167 S100027_02167 2073368 2073739 + UPF0713 protein YngL Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0713 family gene gene2166 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02167 S100027_02168 S100027_02168 S100027_02168 2074108 2075712 + Cellulase Carbohydrate metabolism%3B Cellulose degradation%3B Glycosidase%3B Hydrolase%3B Polysaccharide degradation%3B Signal%3B Belongs to the glycosyl hydrolase 5 (cellulase A) family%3B Contains 1 CBM3 (carbohydrate binding type-3) domain%3B KEGG: bld:BLi02088 endoglucanase gene gene2167 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02168 S100027_02169 S100027_02169 S100027_02169 2075811 2076068 + uncharacterized protein Phosphoprotein. gene gene2168 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02169 S100027_02170 S100027_02170 S100027_02170 2076095 2076601 + Ribosomal-protein-alanine N-acetyltransferase Contains 1 N-acetyltransferase domain%3B KEGG: pat:Patl_0113 ribosomal-protein-alanine N-acetyltransferase gene gene2169 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02170 S100027_02171 S100027_02171 S100027_02171 2077147 2078283 - 1-alkyl-2-acetylglycerophosphocholine esterase KEGG: cel:CELE_W03G9. 6 platelet-activating factor acetylhydrolase gene gene2170 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02171 S100027_02172 S100027_02172 trxB trxB 2079006 2079923 - Thioredoxin-disulfide reductase Disulfide bond%3B FAD%3B Flavoprotein%3B Glycoprotein%3B NADP%3B Oxidoreductase%3B Redox-active center%3B Secreted%3B Signal%3B Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: cgl:NCgl0663 thioredoxin reductase (NADPH) gene gene2171 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02172 S100027_02173 S100027_02173 S100027_02173 2079976 2080866 - hypothetical protein gene gene2172 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02173 S100027_02174 S100027_02174 S100027_02174 2080971 2081396 - Protein rrf2 DNA-binding%3B Contains 1 HTH rrf2-type DNA-binding domain gene gene2173 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02174 S100027_02175 S100027_02175 S100027_02175 2081787 2083193 - uncharacterized protein Repeat%3B Secreted%3B Signal%3B Contains 8 PbH1 repeats gene gene2174 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02175 S100027_02176 S100027_02176 S100027_02176 2083331 2084647 - Branched-chain amino acid transport system carrier protein BrnQ Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Component of the transport system for branched-chain amino acids (leucine%2C isoleucine and valine) Which is coupled to a proton motive force%3B Belongs to the branched chain amino acid transporter family gene gene2175 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02176 S100027_02177 S100027_02177 yahK yahK 2085209 2086267 - putative formaldehyde dehydrogenase AdhA Metal-binding%3B Oxidoreductase%3B Stress response%3B Zinc%3B Functions in the protection against aldehyde-stress%3B Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: bli:BL05196 uncharacterized zinc-type alcohol dehydrogenase-like protein%3B Oxidoreductases gene gene2176 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02177 S100027_02178 S100027_02178 S100027_02178 2086473 2086868 + putative HTH-type transcriptional regulator DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH merR-type DNA-binding domain gene gene2177 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02178 S100027_02179 S100027_02179 S100027_02179 2086895 2087158 - Phosphocarrier protein HPr Cytoplasm%3B Kinase%3B Phosphoprotein%3B Phosphotransferase system%3B Serine/threonine-protein kinase%3B Sugar transport%3B Transcription%3B Transcription regulation%3B Transferase%3B Transport%3B General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the permease (enzymes II/III). P-Ser-HPr interacts with the catabolite control protein A (CcpA)%2C forming a complex that binds to DNA at the catabolite response elements cre%2C operator sites preceding a large number of catabolite-regulated genes. Thus%2C P-Ser-HPr is a corepressor in carbon catabolite repression (CCR)%2C a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion%2C in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity)%3B Belongs to the HPr family%3B Contains 1 HPr domain gene gene2178 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02179 S100027_02180 S100027_02180 S100027_02180 2087356 2088393 - N-acetylphosphatidylethanolamine-hydrolyzing phospholipase D Acetylation%3B Hydrolase%3B Lipid degradation%3B Lipid metabolism%3B Membrane%3B Metal-binding%3B Phospholipid degradation%3B Phospholipid metabolism%3B Polymorphism%3B Zinc%3B Hydrolyzes N-acyl-phosphatidylethanolamines (NAPEs) to produce N-acylethanolamines (NAEs) and phosphatidic acid. Responsible for the generation of anandamide (N- arachidonoylethanolamine)%2C the ligand of cannabinoid and vanilloid receptors (By similarity)%3B Belongs to the NAPE-PLD family%3B KEGG: hmg:100205873 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D gene gene2179 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02180 S100027_02181 S100027_02181 S100027_02181 2088611 2089063 - hypothetical protein gene gene2180 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02181 S100027_02182 S100027_02182 paaF paaF 2089134 2090195 - Enoyl-CoA hydratase Lyase%3B Belongs to the enoyl-CoA hydratase/isomerase family%3B KEGG: ngl:RG1141_CH32070 enoyl-CoA hydratase gene gene2181 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02182 S100027_02183 S100027_02183 fadB fadB 2090211 2090996 - Enoyl-CoA hydratase Fatty acid metabolism%3B Lipid degradation%3B Lipid metabolism%3B Lyase%3B Involved in the degradation of long-chain fatty acids. Belongs to the enoyl-CoA hydratase/isomerase family%3B KEGG: blh:BaLi_c21690 enoyl-CoA hydratase gene gene2182 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02183 S100027_02184 S100027_02184 mmsA mmsA 2091079 2092533 - Malonate-semialdehyde dehydrogenase (acetylating) NAD%3B Oxidoreductase%3B Converts malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA%2C respectively%3B Belongs to the aldehyde dehydrogenase family. IolA subfamily%3B KEGG: bli:BL00293 malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase gene gene2183 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02184 S100027_02185 S100027_02185 garR garR 2092552 2093439 - 2-hydroxy-3-oxopropionate reductase Branched-chain amino acid catabolism%3B Mitochondrion%3B NAD%3B Oxidoreductase%3B Transit peptide%3B Belongs to the 3-hydroxyisobutyrate dehydrogenase family%3B KEGG: pae:PA1500 2-hydroxy-3-oxopropionate reductase gene gene2184 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02185 S100027_02186 S100027_02186 S100027_02186 2093455 2095170 - putative acyl-CoA dehydrogenase FAD%3B Fatty acid metabolism%3B Flavoprotein%3B Lipid degradation%3B Lipid metabolism%3B Oxidoreductase%3B Involved in the degradation of long-chain fatty acids. Belongs to the acyl-CoA dehydrogenase family%3B KEGG: bli:BL00291 null%3B With other acceptors gene gene2185 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02186 S100027_02187 S100027_02187 manA manA 2095628 2096581 - Mannose-6-phosphate isomerase Isomerase%3B Metal-binding%3B Zinc%3B Belongs to the mannose-6-phosphate isomerase type 1 family%3B KEGG: bli:BL00290 mannose-6-phosphate isomerase gene gene2186 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02187 S100027_02188 S100027_02188 fruA fruA 2096600 2098543 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Kinase%3B Membrane%3B Phosphotransferase system%3B Repeat%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport. Contains 2 PTS EIIB type-2 domains%3B Contains 1 PTS EIIC type-2 domain%3B KEGG: pse:NH8B_1236 PTS system%2C fructose-specific IIB component gene gene2187 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02188 S100027_02189 S100027_02189 S100027_02189 2098946 2099287 + hypothetical protein gene gene2188 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02189 S100027_02190 S100027_02190 S100027_02190 2099766 2099936 - hypothetical protein gene gene2189 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02190 S100027_02191 S100027_02191 S100027_02191 2100091 2100363 - hypothetical protein gene gene2190 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02191 S100027_02192 S100027_02192 S100027_02192 2100478 2102421 - Transcriptional regulator ManR Activator%3B DNA-binding%3B Kinase%3B Phosphoprotein%3B Repeat%3B Transcription%3B Transcription regulation%3B Transferase%3B Positively regulates the expression of the mannose operon that consists of three genes%2C manP%2C manA%2C and yjdF%2C which are responsible for the transport and utilization of mannose. Also activates its own expression%3B Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains%3B Contains 1 PTS EIIA type-2 domain%3B Contains 1 PTS EIIB type-2 domain gene gene2191 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02192 S100027_02193 S100027_02193 S100027_02193 2102727 2103383 - hypothetical protein gene gene2192 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02193 S100027_02194 S100027_02194 S100027_02194 2103367 2104245 - Energy-coupling factor transporter ATP-binding protein EcfA1 ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the ABC transporter superfamily. Energy- coupling factor EcfA family%3B Contains 1 ABC transporter domain gene gene2193 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02194 S100027_02195 S100027_02195 S100027_02195 2104248 2104622 - putative HTH-type transcriptional regulator YhcF DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH gntR-type DNA-binding domain gene gene2194 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02195 S100027_02196 S100027_02196 S100027_02196 2104912 2105763 - putative oxidoreductase NAD%3B Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bha:BH0707 null%3B Oxidoreductases gene gene2195 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02196 S100027_02197 S100027_02197 S100027_02197 2105801 2106865 - Mannonate dehydratase Iron%3B Lyase%3B Manganese%3B Catalyzes the dehydration of D-mannonate%3B Belongs to the mannonate dehydratase family%3B KEGG: bur:Bcep18194_B1358 mannonate dehydratase gene gene2196 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02197 S100027_02198 S100027_02198 S100027_02198 2107116 2109524 - Alpha-glucosidase Carbohydrate metabolism%3B Cell wall biogenesis/degradation%3B Glycoprotein%3B Glycosidase%3B Hydrolase%3B Polysaccharide degradation%3B Secreted%3B Signal%3B Glucosidase involved in the degradation of cellulosic biomass. Has both alpha- and beta-glucosidase activity (By similarity)%3B Belongs to the glycosyl hydrolase 31 family%3B KEGG: bli:BL00280 alpha-glucosidase gene gene2197 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02198 S100027_02199 S100027_02199 S100027_02199 2109544 2110839 - uncharacterized protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the YiaN/YgiK family gene gene2198 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02199 S100027_02200 S100027_02200 S100027_02200 2110878 2111393 - Putative TRAP transporter small permease protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the TRAP transporter small permease family gene gene2199 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02200 S100027_02201 S100027_02201 S100027_02201 2111444 2112454 - C4-dicarboxylate-binding protein DctB Secreted%3B Signal%3B Sugar transport%3B Transport%3B Part of the binding-protein-dependent transport system for uptake of C4-dicarboxylates. Responsible for growth on fumarate and succinate but not malate. Is not directly involved in C4-dicarboxylate uptake%2C but plays a sensory role in the DctS/DctR two-component system which regulates the expression of the dctA C4-dicarboxylate transporter%3B Belongs to the bacterial solute-binding protein 7 family gene gene2200 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02201 S100027_02202 S100027_02202 S100027_02202 2112913 2113923 + Catabolite control protein A Activator%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA)%2C which ensures optimal energy usage under diverse conditions%3B Contains 1 HTH lacI-type DNA-binding domain gene gene2201 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02202 S100027_02203 S100027_02203 arsC arsC 2114138 2114557 - Arsenate reductase (glutaredoxin) Arsenical resistance%3B Disulfide bond%3B Hydrolase%3B Oxidoreductase%3B Redox-active center%3B Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins%2C low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances%3B Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family%3B KEGG: bsr:I33_0599 arsenate reductase gene gene2202 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02203 S100027_02204 S100027_02204 S100027_02204 2114580 2115875 - Arsenical pump membrane protein Arsenical resistance%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in arsenical resistance. Thought to form the channel of an arsenite pump. Belongs to the ArsB family gene gene2203 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02204 S100027_02205 S100027_02205 S100027_02205 2115999 2116346 - HTH-type transcriptional repressor AseR Cytoplasm%3B DNA-binding%3B Metal-binding%3B Metal-thiolate cluster%3B Repressor%3B Transcription%3B Transcription regulation%3B Metal-responsive transcriptional regulator that represses transcription of the aseR-ydfA operon by binding specifically to its promoter. Binding of arsenite or antimonite causes the repressor to dissociate from the DNA%3B Contains 1 HTH arsR-type DNA-binding domain gene gene2204 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02205 S100027_02206 S100027_02206 S100027_02206 2116835 2117428 - uncharacterized protein gene gene2205 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02206 S100027_02207 S100027_02207 S100027_02207 2117550 2118275 + hypothetical protein gene gene2206 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02207 S100027_02208 S100027_02208 S100027_02208 2118498 2119355 - putative glucose uptake protein Cell membrane%3B Membrane%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the uptake of glucose%3B Belongs to the GRP transporter (TC 2. A. 7. 5) family gene gene2207 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02208 S100027_02209 S100027_02209 S100027_02209 2119477 2120664 - N-acetylmuramoyl-L-alanine amidase Signal%3B Belongs to the UPF0748 family%3B KEGG: esr:ES1_16340 N-acetylmuramoyl-L-alanine amidase gene gene2208 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02209 S100027_02210 S100027_02210 S100027_02210 2121082 2121435 - Oligoribonuclease NrnB Cytoplasm%3B Exonuclease%3B Hydrolase%3B Nuclease%3B Degrades RNA oligonucleotides with a length of 5 nucleotides in a 3'- to 5'-direction. Less active on shorter RNA oligonucleotides and on those with a length of 24 nucleotides. Prefers RNA oligonucleotides containing adenines rather than cytosines gene gene2209 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02210 S100027_02211 S100027_02211 S100027_02211 2121476 2121799 - Oligoribonuclease NrnB Cytoplasm%3B Exonuclease%3B Hydrolase%3B Nuclease%3B Degrades RNA oligonucleotides with a length of 5 nucleotides in a 3'- to 5'-direction. Less active on shorter RNA oligonucleotides and on those with a length of 24 nucleotides. Prefers RNA oligonucleotides containing adenines rather than cytosines gene gene2210 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02211 S100027_02212 S100027_02212 pflA pflA 2121954 2122712 - [Formate-C-acetyltransferase]-activating enzyme 4Fe-4S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase%3B S-adenosyl-L-methionine%3B Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical%2C using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. Belongs to the organic radical-activating enzymes family%3B KEGG: bli:BL01864 pyruvate formate lyase activating enzyme gene gene2211 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02212 S100027_02213 S100027_02213 pflD pflD 2122770 2124995 - Formate C-acetyltransferase Acyltransferase%3B Carbohydrate metabolism%3B Cytoplasm%3B Glucose metabolism%3B Organic radical%3B Transferase%3B Contains 1 glycine radical domain%3B Contains 1 PFL domain%3B KEGG: bli:BL01863 formate C-acetyltransferase gene gene2212 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02213 S100027_02214 S100027_02214 dacB dacB 2125493 2126962 - D-alanyl-D-alanine carboxypeptidase DacC Cell cycle%3B Cell division%3B Cell shape%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Peptidoglycan synthesis%3B Secreted%3B Signal%3B Catalyzes DD-carboxypeptidase and transpeptidation reactions%3B Belongs to the peptidase S13 family%3B KEGG: bli:BL01997 D-alanyl-D-alanine carboxypeptidase / D-alanyl-D-alanine-endopeptidase (penicillin-binding protein 4)%3B Serine-type D-Ala-D-Ala carboxypeptidase gene gene2213 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02214 S100027_02215 S100027_02215 S100027_02215 2127209 2127892 - UPF0702 transmembrane protein YetF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0702 family gene gene2214 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02215 S100027_02216 S100027_02216 S100027_02216 2128013 2129506 - Cardiolipin synthase Cell membrane%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Repeat%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol%3B Belongs to the phospholipase D family. Cardiolipin synthase subfamily%3B Contains 2 PLD phosphodiesterase domains%3B KEGG: ban:BA_2054 cardiolipin synthase%3B Transferases for other substituted phosphate groups gene gene2215 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02216 S100027_02217 S100027_02217 S100027_02217 2129859 2130269 - UPF0702 transmembrane protein YetF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0702 family gene gene2216 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02217 S100027_02218 S100027_02218 S100027_02218 2130482 2131342 - UPF0702 transmembrane protein YetF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0702 family gene gene2217 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02218 S100027_02219 S100027_02219 S100027_02219 2131372 2131578 - hypothetical protein gene gene2218 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02219 S100027_02220 S100027_02220 S100027_02220 2131590 2131940 - Stage V sporulation protein AEB Sporulation. gene gene2219 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02220 S100027_02221 S100027_02221 S100027_02221 2131937 2132956 - Stage V sporulation protein AD Sporulation. gene gene2220 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02221 S100027_02222 S100027_02222 S100027_02222 2132956 2133369 - Stage V sporulation protein AC Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix. gene gene2221 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02222 S100027_02223 S100027_02223 S100027_02223 2133429 2133761 + hypothetical protein gene gene2222 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02223 S100027_02224 S100027_02224 S100027_02224 2133731 2134591 + putative transposase-like protein DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene2223 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02224 S100027_02225 S100027_02225 S100027_02225 2134658 2135548 - hypothetical protein gene gene2224 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02225 S100027_02226 S100027_02226 S100027_02226 2135617 2135823 - hypothetical protein gene gene2225 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02226 S100027_02227 S100027_02227 S100027_02227 2136231 2136683 - Spore germination protein XC Cell membrane%3B Germination%3B Lipoprotein%3B Membrane%3B Palmitate%3B Plasmid%3B Signal%3B Virulence%3B May allow B. anthracis to germinate within phagocytic cells and therefore involved in virulence. Belongs to the GerABKC lipoprotein family gene gene2226 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02227 S100027_02228 S100027_02228 S100027_02228 2136698 2137711 - Spore germination protein Cell membrane%3B Germination%3B Membrane%3B Plasmid%3B Transmembrane%3B Transmembrane helix%3B Virulence%3B May allow B. anthracis to germinate within phagocytic cells and therefore involved in virulence. Belongs to the GerABKA family gene gene2227 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02228 S100027_02229 S100027_02229 S100027_02229 2137665 2137967 - N-acetylmuramoyl-L-alanine amidase Cell wall%3B Cell wall biogenesis/degradation%3B Competence%3B Hydrolase%3B Metal-binding%3B Repeat%3B Secreted%3B Sporulation%3B Zinc%3B Autolysins are involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella - in particular of its basal body - and sporulation. CwlC is able to hydrolyze type A cell walls such as B. subtilis. Its main function is to lyze the mother cell wall peptidoglycan%2C playing a role during sporulation%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B Contains 1 SPOR domain%3B KEGG: bsu:BSU17410 N-acetylmuramoyl-L-alanine amidase gene gene2228 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02229 S100027_02230 S100027_02230 S100027_02230 2138329 2138781 + hypothetical protein gene gene2229 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02230 S100027_02231 S100027_02231 S100027_02231 2138841 2139743 + transposase DNA recombination%3B DNA-binding%3B Plasmid%3B Transposable element%3B Transposition%3B Transposase for transposon Tn1546. Required for transposition of transposon Tn1546. Belongs to the transposase 7 family gene gene2230 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02231 S100027_02232 S100027_02232 S100027_02232 2139720 2140514 - hypothetical protein gene gene2231 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02232 S100027_02233 S100027_02233 S100027_02233 2140596 2141774 - NADH dehydrogenase FAD%3B Flavoprotein%3B Oxidoreductase%3B Belongs to the NADH dehydrogenase family%3B KEGG: bsu:BSU12290 NADH dehydrogenase gene gene2232 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02233 S100027_02234 S100027_02234 S100027_02234 2141811 2142245 - uncharacterized protein gene gene2233 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02234 S100027_02235 S100027_02235 S100027_02235 2142197 2142520 - hypothetical protein gene gene2234 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02235 S100027_02236 S100027_02236 S100027_02236 2142655 2142885 - Glucose-6-phosphate isomerase KEGG: bbe:BBR47_08920 glucose-6-phosphate isomerase gene gene2235 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02236 S100027_02237 S100027_02237 S100027_02237 2142978 2143202 + uncharacterized protein Coiled coil. gene gene2236 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02237 S100027_02238 S100027_02238 acsS acsS 2143284 2145236 - Acetate--CoA ligase Acetylation%3B ATP-binding%3B Ligase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Catalyzes the conversion of acetate into acetyl-CoA (AcCoA)%2C an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction%2C AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction%2C it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA%2C forming the product AcCoA%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bli:BL01993 acetyl-CoA synthetase gene gene2237 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02238 S100027_02239 S100027_02239 pccB pccB 2145267 2146796 - Propionyl-CoA carboxylase ATP-binding%3B Ligase%3B Nucleotide-binding%3B Belongs to the AccD/PCCB family%3B Contains 1 carboxyltransferase domain%3B KEGG: obt:OPIT5_14445 propionyl-CoA carboxylase beta chain gene gene2238 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02239 S100027_02240 S100027_02240 S100027_02240 2146817 2147599 - Enoyl-CoA hydratase Lyase%3B Belongs to the enoyl-CoA hydratase/isomerase family%3B KEGG: lan:Lacal_1125 enoyl-CoA hydratase gene gene2239 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02240 S100027_02241 S100027_02241 hmgL hmgL 2147619 2148530 - Hydroxymethylglutaryl-CoA lyase Lyase%3B Metal-binding%3B Involved in the catabolism of branched amino acids such as leucine%3B Belongs to the HMG-CoA lyase family%3B KEGG: bli:BL01990 hydroxymethylglutaryl-CoA lyase gene gene2240 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02241 S100027_02242 S100027_02242 S100027_02242 2148548 2148760 - Biotin/lipoyl attachment protein Biotin%3B Lipoyl%3B Contains 1 biotinyl-binding domain gene gene2241 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02242 S100027_02243 S100027_02243 accC accC 2148778 2150118 - Acetyl-CoA carboxylase ATP-binding%3B Biotin%3B Ligase%3B Magnesium%3B Nucleotide-binding%3B Contains 1 ATP-grasp domain%3B Contains 1 biotin carboxylation domain%3B KEGG: wgl:WIGMOR_0138 acetyl-CoA carboxylase%2C biotin carboxylase subunit gene gene2242 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02243 S100027_02244 S100027_02244 S100027_02244 2150161 2151798 - Putative acyl-CoA synthetase YngI ATP-binding%3B Ligase%3B Nucleotide-binding%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bli:BL01987 fatty-acyl-CoA synthase%3B Acid--thiol ligases gene gene2243 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02244 S100027_02245 S100027_02245 S100027_02245 2151830 2152990 - Short-chain acyl-CoA dehydrogenase FAD%3B Flavoprotein%3B Oxidoreductase%3B Belongs to the acyl-CoA dehydrogenase family%3B KEGG: oih:OB1695 butyryl-CoA dehydrogenase gene gene2244 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02245 S100027_02246 S100027_02246 S100027_02246 2153221 2153781 + NAD(P)H dehydrogenase (quinone) Cell inner membrane%3B Cell membrane%3B Flavoprotein%3B FMN%3B Membrane%3B NAD%3B Oxidoreductase%3B Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity%2C but this enzymatic activity is not required for activation of KefC%3B Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily%3B KEGG: cvi:CV_0290 NAD(P)H dehydrogenase (quinone) gene gene2245 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02246 S100027_02247 S100027_02247 S100027_02247 2153823 2154173 - putative HTH-type transcriptional regulator DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH hxlR-type DNA-binding domain gene gene2246 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02247 S100027_02248 S100027_02248 S100027_02248 2154385 2155656 - Glutamate-5-semialdehyde dehydrogenase Amino-acid biosynthesis%3B Cytoplasm%3B NADP%3B Oxidoreductase%3B Proline biosynthesis%3B Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate%3B Belongs to the gamma-glutamyl phosphate reductase family%3B KEGG: bli:BL01984 glutamate-5-semialdehyde dehydrogenase gene gene2247 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02248 S100027_02249 S100027_02249 S100027_02249 2155682 2156803 - Glutamate 5-kinase Amino-acid biosynthesis%3B ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Proline biosynthesis%3B Transferase%3B Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate%3B Belongs to the glutamate 5-kinase family%3B Contains 1 PUA domain%3B KEGG: bli:BL01983 glutamate 5-kinase gene gene2248 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02249 S100027_02250 S100027_02250 S100027_02250 2156842 2157642 - Pyrroline-5-carboxylate reductase Amino-acid biosynthesis%3B Cytoplasm%3B NADP%3B Oxidoreductase%3B Proline biosynthesis%3B Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline%3B Belongs to the pyrroline-5-carboxylate reductase family%3B KEGG: bsu:BSU18480 pyrroline-5-carboxylate reductase gene gene2249 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02250 S100027_02251 S100027_02251 S100027_02251 2157890 2158093 - hypothetical protein gene gene2250 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02251 S100027_02252 S100027_02252 S100027_02252 2158044 2158721 - UPF0702 transmembrane protein YetF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0702 family gene gene2251 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02252 S100027_02253 S100027_02253 S100027_02253 2159025 2160164 - Sulfate permease CysP Cell membrane%3B Membrane%3B Sulfate transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the import of sulfate%3B Belongs to the inorganic phosphate transporter (PiT) (TC 2. A. 20) family gene gene2252 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02253 S100027_02254 S100027_02254 S100027_02254 2160179 2160889 - Phosphoadenylyl-sulfate reductase (thioredoxin) Cytoplasm%3B Oxidoreductase%3B Reduction of activated sulfate into sulfite%3B Belongs to the PAPS reductase family. CysH subfamily%3B KEGG: bli:BL01979 phosphoadenosine phosphosulfate reductase gene gene2253 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02254 S100027_02255 S100027_02255 comA comA 2161437 2162201 + Phosphosulfolactate synthase Coenzyme M biosynthesis%3B Lyase%3B Catalyzes the addition of sulfite to phosphoenolpyruvate (PEP) to yield (2R)-phospho-3-sulfolactate (PSL)%3B Belongs to the phosphosulfolactate synthase family%3B KEGG: bli:BL02005 phosphosulfolactate synthase gene gene2254 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02255 S100027_02256 S100027_02256 S100027_02256 2162219 2162842 - UPF0750 membrane protein YitE Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0750 family gene gene2255 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02256 S100027_02257 S100027_02257 S100027_02257 2162936 2164042 - Putative isomerase YitF Isomerase%3B Magnesium%3B Metal-binding%3B Belongs to the mandelate racemase/muconate lactonizing enzyme family%3B KEGG: bss:BSUW23_05560 D-galactarolactone cycloisomerase%3B Intramolecular lyases gene gene2256 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02257 S100027_02258 S100027_02258 S100027_02258 2164059 2165303 - putative MFS-type transporter YitG Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene2257 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02258 S100027_02259 S100027_02259 dpm1 dpm1 2165375 2166382 - Dolichyl-phosphate beta-D-mannosyltransferase Cell membrane%3B Glycosyltransferase%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Belongs to the glycosyltransferase 2 family%3B KEGG: fco:FCOL_06185 dolichol-phosphate mannosyltransferase gene gene2258 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02259 S100027_02260 S100027_02260 S100027_02260 2166405 2168120 - putative membrane protein YkoS Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2259 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02260 S100027_02261 S100027_02261 S100027_02261 2168246 2168431 - hypothetical protein gene gene2260 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02261 S100027_02262 S100027_02262 gltD gltD 2168654 2170135 - Glutamate synthase (NADPH) Amino-acid biosynthesis%3B Glutamate biosynthesis%3B NADP%3B Oxidoreductase%3B Belongs to the glutamate synthase family%3B KEGG: rso:RSc2964 glutamate synthase (NADPH/NADH) small chain gene gene2261 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02262 S100027_02263 S100027_02263 gltB gltB 2170152 2174717 - Glutamate synthase (NADPH) 3Fe-4S%3B Amino-acid biosynthesis%3B FAD%3B Flavoprotein%3B FMN%3B Glutamate biosynthesis%3B Glutamine amidotransferase%3B Iron%3B Iron-sulfur%3B Metal-binding%3B NADP%3B Oxidoreductase%3B Belongs to the glutamate synthase family%3B Contains 1 glutamine amidotransferase type-2 domain%3B KEGG: bsu:BSU18450 glutamate synthase (NADPH/NADH) large chain gene gene2262 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02263 S100027_02264 S100027_02264 S100027_02264 2174866 2175768 + HTH-type transcriptional regulator BsdA Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Could be a positive regulator of bsdBCD expression in response to salicylic acid%3B Contains 1 HTH lysR-type DNA-binding domain gene gene2263 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02264 S100027_02265 S100027_02265 S100027_02265 2175906 2176118 + hypothetical protein gene gene2264 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02265 S100027_02266 S100027_02266 S100027_02266 2176174 2178099 - hypothetical protein gene gene2265 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02266 S100027_02267 S100027_02267 S100027_02267 2178233 2179807 + hypothetical protein gene gene2266 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02267 S100027_02268 S100027_02268 S100027_02268 2179947 2180420 + hypothetical protein gene gene2267 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02268 S100027_02269 S100027_02269 S100027_02269 2180417 2182144 + Putative export ATP-binding/permease protein ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of an ABC transporter complex. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP- binding domain (NBD) is responsible for energy generation (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene2268 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02269 S100027_02270 S100027_02270 S100027_02270 2182141 2183964 + Lipid A export ATP-binding/permease protein MsbA ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Lipid transport%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation%3B Belongs to the ABC transporter superfamily. Lipid exporter (TC 3. A. 1. 106) family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene2269 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02270 S100027_02271 S100027_02271 cypX cypX 2184199 2185413 + Pulcherriminic acid synthase Heme%3B Iron%3B Metal-binding%3B Monooxygenase%3B Oxidoreductase%3B Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds%2C including steroids%2C fatty acids%2C and xenobiotics. Belongs to the cytochrome P450 family%3B KEGG: pao:Pat9b_5697 pulcherriminic acid synthase gene gene2270 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02271 S100027_02272 S100027_02272 idnO idnO 2185462 2186178 - Gluconate 5-dehydrogenase Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: smw:SMWW4_v1c33960 gluconate 5-dehydrogenase gene gene2271 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02272 S100027_02273 S100027_02273 S100027_02273 2186818 2189151 + Pyruvate%2C water dikinase Transferase%3B Might catalyze the phosphorylation of pyruvate to phosphoenolpyruvate%3B Belongs to the PEP-utilizing enzyme family%3B KEGG: bsu:BSU18830 pyruvate%2C water dikinase gene gene2272 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02273 S100027_02274 S100027_02274 S100027_02274 2189626 2191050 + putative MFS-type transporter YvkA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily. TCR/Tet family gene gene2273 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02274 S100027_02275 S100027_02275 napA napA 2191197 2193236 + Nitrate reductase Iron%3B Iron-sulfur%3B Metal-binding%3B Molybdenum%3B Oxidoreductase%3B Belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: ccc:G157_05015 periplasmic nitrate reductase NapA gene gene2274 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02275 S100027_02276 S100027_02276 S100027_02276 2193276 2193752 - HTH-type transcriptional regulator MhqR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Negatively regulates mhqA%2C mhqED%2C mhqNOP%2C and azoR2 which may contribute to the degradation of aromatic compounds%3B Contains 1 HTH marR-type DNA-binding domain gene gene2275 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02276 S100027_02277 S100027_02277 S100027_02277 2193891 2195411 + putative MFS-type transporter YusP Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily. EmrB family%3B KEGG: nhe:NECHADRAFT_65858 DNA repair protein RAD50%3B Acting on acid anhydrides gene gene2276 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02277 S100027_02278 S100027_02278 S100027_02278 2195416 2196513 - Spore germination protein YndE Amino-acid transport%3B Cell membrane%3B Germination%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the germinative response to L-alanine. Could be an amino acid transporter (By similarity)%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2. A. 3. 9) family gene gene2277 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02278 S100027_02279 S100027_02279 S100027_02279 2196553 2197749 - Spore germination protein YndF Cell membrane%3B Germination%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B May be involved in spore germination%3B Belongs to the GerABKC lipoprotein family gene gene2278 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02279 S100027_02280 S100027_02280 S100027_02280 2197736 2198836 - Spore germination protein A2 Amino-acid transport%3B Cell membrane%3B Germination%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the germinative response to L-alanine. Could be an amino acid transporter. Forms a complex at the inner spore membrane which acts as a receptor for L-alanine%2C thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors%2C respectively)%2C but the response is improved in their presence. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2. A. 3. 9) family gene gene2279 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02280 S100027_02281 S100027_02281 S100027_02281 2198864 2199964 - Spore germination protein A2 Amino-acid transport%3B Cell membrane%3B Germination%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the germinative response to L-alanine. Could be an amino acid transporter. Forms a complex at the inner spore membrane which acts as a receptor for L-alanine%2C thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors%2C respectively)%2C but the response is improved in their presence. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2. A. 3. 9) family gene gene2280 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02281 S100027_02282 S100027_02282 S100027_02282 2199987 2201555 - putative membrane protein YndD Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the GerABKA family gene gene2281 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02282 S100027_02283 S100027_02283 S100027_02283 2201832 2203559 - Aliphatic sulfonates import ATP-binding protein SsuB ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3. A. 1. 17. 2) family%3B Contains 1 ABC transporter domain%3B KEGG: xbo:XBJ1_2227 zinc transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene2282 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02283 S100027_02284 S100027_02284 S100027_02284 2203999 2205984 + Methyl-accepting chemotaxis protein McpB Cell membrane%3B Chemotaxis%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpB is required for taxis towards asparagine%2C aspartate%2C glutamine%2C and histidine%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene2283 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02284 S100027_02285 S100027_02285 S100027_02285 2206030 2206362 - Protein CsaA Chaperone%3B Cytoplasm%3B Protein transport%3B RNA-binding%3B Translocation%3B Transport%3B tRNA-binding%3B Could serves as a molecular chaperone for exported proteins or alternatively acts by stabilizing the SecA protein. Contains 1 tRNA-binding domain gene gene2284 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02285 S100027_02286 S100027_02286 aprX aprX 2206585 2207913 + Serine protease AprX Cytoplasm%3B Hydrolase%3B Protease%3B Serine protease%3B Displays serine protease activity. Seems to have a broad substrate specificity%3B Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bli:BL00903 serine protease AprX%3B Serine endopeptidases gene gene2285 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02286 S100027_02287 S100027_02287 S100027_02287 2207965 2208375 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2286 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02287 S100027_02288 S100027_02288 S100027_02288 2208382 2208981 - hypothetical protein gene gene2287 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02288 S100027_02289 S100027_02289 S100027_02289 2209118 2209609 - putative HTH-type transcriptional regulator YvmB DNA-binding%3B Transcription%3B Transcription regulation%3B Involved in protein secretion. Contains 1 HTH marR-type DNA-binding domain gene gene2288 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02289 S100027_02290 S100027_02290 nadD nadD 2209753 2210184 + Nicotinate-nucleotide adenylyltransferase KEGG: bfi:CIY_18840 nicotinate-nucleotide adenylyltransferase gene gene2289 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02290 S100027_02291 S100027_02291 S100027_02291 2210431 2210916 - hypothetical protein gene gene2290 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02291 S100027_02292 S100027_02292 S100027_02292 2210947 2212593 - putative membrane protein YndJ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2291 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02292 S100027_02293 S100027_02293 S100027_02293 2212590 2213207 - uncharacterized protein gene gene2292 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02293 S100027_02294 S100027_02294 S100027_02294 2213209 2214108 - putative membrane protein YndG Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2293 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02294 S100027_02295 S100027_02295 S100027_02295 2214351 2214923 - putative HTH-type transcriptional regulator YobS DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH tetR-type DNA-binding domain gene gene2294 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02295 S100027_02296 S100027_02296 S100027_02296 2214931 2215644 - uncharacterized protein Hydrolase%3B Metal-binding%3B Zinc%3B Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family gene gene2295 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02296 S100027_02297 S100027_02297 S100027_02297 2215726 2216199 - Putative transcriptional regulator protein YobU gene gene2296 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02297 S100027_02298 S100027_02298 S100027_02298 2216196 2216477 - hypothetical protein gene gene2297 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02298 S100027_02299 S100027_02299 S100027_02299 2216531 2217466 - putative HTH-type transcriptional regulator YobV Cytoplasm%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH deoR-type DNA-binding domain gene gene2298 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02299 S100027_02300 S100027_02300 S100027_02300 2217670 2218167 + Protein csk22 Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix. gene gene2299 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02300 S100027_02301 S100027_02301 S100027_02301 2218206 2218538 - HTH-type transcriptional repressor CzrA Cytoplasm%3B DNA-binding%3B Metal-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Zinc%3B Metal-responsive transcriptional regulator that represses transcription of cadA and the czcD-trkA operon by binding specifically to their promoter. Binding of zinc causes the repressor to dissociate from the DNA%3B Contains 1 HTH arsR-type DNA-binding domain gene gene2300 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02301 S100027_02302 S100027_02302 S100027_02302 2218614 2219438 - uncharacterized protein gene gene2301 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02302 S100027_02303 S100027_02303 S100027_02303 2219603 2219845 - uncharacterized protein Phosphoprotein. gene gene2302 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02303 S100027_02304 S100027_02304 S100027_02304 2219998 2221335 + Low-affinity putrescine importer PlaP Amino-acid transport%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Putrescine importer%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene2303 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02304 S100027_02305 S100027_02305 S100027_02305 2221470 2222078 + putative membrane protein YocA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2304 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02305 S100027_02306 S100027_02306 capD capD 2222006 2223196 - UDP-glucose 4-epimerase Belongs to the polysaccharide synthase family%3B KEGG: yfr:AW19_2183 UDP-glucose 4-epimerase gene gene2305 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02306 S100027_02307 S100027_02307 S100027_02307 2223249 2223887 - hypothetical protein gene gene2306 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02307 S100027_02308 S100027_02308 S100027_02308 2224084 2224497 - hypothetical protein gene gene2307 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02308 S100027_02309 S100027_02309 waaG waaG 2224512 2225720 - N-acetyl-alpha-D-glucosaminyl L-malate synthase Glycosyltransferase%3B Nucleotide-binding%3B Transferase%3B Involved in bacillithiol (BSH) biosynthesis. Catalyzes the first step of the pathway%2C the formation of N- acetylglucosaminylmalate (GlcNAc-Mal) from UDP-N-acetylglucosamine (UDP-GlcNAc) and L-malate%3B Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: cko:CKO_05089 UDP-glucose:(heptosyl)LPS alpha-1%2C3-glucosyltransferase%3B Hexosyltransferases gene gene2308 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02309 S100027_02310 S100027_02310 S100027_02310 2225882 2226415 - putative membrane protein YozB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2309 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02310 S100027_02311 S100027_02311 S100027_02311 2226568 2227548 - hypothetical protein gene gene2310 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02311 S100027_02312 S100027_02312 S100027_02312 2227778 2228287 + uncharacterized protein Coiled coil. gene gene2311 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02312 S100027_02313 S100027_02313 S100027_02313 2228360 2229949 - Putative uncharacterized symporter Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene2312 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02313 S100027_02314 S100027_02314 S100027_02314 2230108 2230914 - Cell wall-binding protein YocH Cell wall%3B Repeat%3B Secreted%3B Signal%3B Contains 2 LysM repeats%3B KEGG: gwc:GWCH70_1211 peptidoglycan endopeptidase LytE%3B Acting on peptide bonds (peptidases) gene gene2313 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02314 S100027_02315 S100027_02315 recQ recQ 2231150 2232955 - DNA helicase ATP-binding%3B Cytoplasm%3B DNA damage%3B DNA recombination%3B DNA repair%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B SOS response%3B Probable DNA helicase. Required for DNA repair and intramolecular recombinatio%3B probably has overlapping function with RecS (AC P50729). It probably acts to help generate ss-DNA from ds-DNA breaks%3B Belongs to the helicase family. RecQ subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B Contains 1 HRDC domain%3B KEGG: bli:BL01304 ATP-dependent DNA helicase RecQ gene gene2314 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02315 S100027_02316 S100027_02316 S100027_02316 2233094 2233612 - uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2315 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02316 S100027_02317 S100027_02317 S100027_02317 2233688 2233849 + hypothetical protein gene gene2316 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02317 S100027_02318 S100027_02318 S100027_02318 2234089 2234265 + uncharacterized protein Coiled coil. gene gene2317 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02318 S100027_02319 S100027_02319 S100027_02319 2234391 2234464 + tRNA-Arg tRNA gene2318 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02319 S100027_02320 S100027_02320 S100027_02320 2234648 2235001 - uncharacterized protein gene gene2319 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02320 S100027_02321 S100027_02321 S100027_02321 2235907 2236872 - hypothetical protein gene gene2320 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02321 S100027_02322 S100027_02322 S100027_02322 2237182 2237742 - uncharacterized protein gene gene2321 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02322 S100027_02323 S100027_02323 fdoG fdoG 2237735 2240878 - Formate dehydrogenase 2Fe-2S%3B 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Molybdenum%3B Oxidoreductase%3B Repeat%3B In the C-terminal sectio%3B belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 2Fe-2S ferredoxin-type domain%3B Contains 2 4Fe-4S ferredoxin-type domains%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: bld:BLi02222 formate dehydrogenase major subunit gene gene2322 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02323 S100027_02324 S100027_02324 S100027_02324 2241214 2241870 - hypothetical protein gene gene2323 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02324 S100027_02325 S100027_02325 S100027_02325 2241867 2243531 - Ribonuclease YxiD Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene2324 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02325 S100027_02326 S100027_02326 S100027_02326 2243638 2243844 - hypothetical protein gene gene2325 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02326 S100027_02327 S100027_02327 S100027_02327 2244112 2244777 - uncharacterized protein Contains 1 PilZ domain gene gene2326 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02327 S100027_02328 S100027_02328 S100027_02328 2245026 2245208 - hypothetical protein gene gene2327 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02328 S100027_02329 S100027_02329 S100027_02329 2245370 2245495 - hypothetical protein gene gene2328 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02329 S100027_02330 S100027_02330 S100027_02330 2245507 2245785 - uncharacterized protein gene gene2329 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02330 S100027_02331 S100027_02331 S100027_02331 2245793 2246185 - uncharacterized protein gene gene2330 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02331 S100027_02332 S100027_02332 S100027_02332 2246833 2247111 + hypothetical protein gene gene2331 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02332 S100027_02333 S100027_02333 S100027_02333 2247574 2247861 + uncharacterized protein gene gene2332 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02333 S100027_02334 S100027_02334 S100027_02334 2248151 2249353 - Spore germination protein YndF Cell membrane%3B Germination%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B May be involved in spore germination%3B Belongs to the GerABKC lipoprotein family gene gene2333 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02334 S100027_02335 S100027_02335 S100027_02335 2249593 2250060 + uncharacterized protein Signal. gene gene2334 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02335 S100027_02336 S100027_02336 S100027_02336 2250094 2250936 + hypothetical protein gene gene2335 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02336 S100027_02337 S100027_02337 mtaD mtaD 2251123 2252472 - S-methyl-5'-thioadenosine deaminase Hydrolase%3B Metal-binding%3B Zinc%3B Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine%2C whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine%2C S-adenosyl-L-homocysteine and adenosine to a small extent%3B Belongs to the MTA/SAH deaminase family%3B KEGG: mac:MA1276 5-methylthioadenosine/S-adenosylhomocysteine deaminase gene gene2336 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02337 S100027_02338 S100027_02338 S100027_02338 2252745 2252993 - Spore coat protein Sporulation. gene gene2337 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02338 S100027_02339 S100027_02339 S100027_02339 2253229 2253438 - hypothetical protein gene gene2338 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02339 S100027_02340 S100027_02340 S100027_02340 2253644 2254426 - Chloride peroxidase Antibiotic biosynthesis%3B Oxidoreductase%3B Peroxidase%3B May be a chlorinating enzyme involved in 7- chlorotetracycline biosynthesis. Able to brominate as well%3B Belongs to the bacterial non-heme bromo- and chloro- peroxidases family%3B KEGG: bld:BLi02236 non-heme chloroperoxidase gene gene2339 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02340 S100027_02341 S100027_02341 S100027_02341 2254562 2255053 + SPBc2 prophage-derived uncharacterized protein YoqH Signal. gene gene2340 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02341 S100027_02342 S100027_02342 S100027_02342 2255131 2255367 - Spore coat protein Sporulation. gene gene2341 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02342 S100027_02343 S100027_02343 S100027_02343 2255541 2256164 + Homoserine/homoserine lactone efflux protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Conducts the efflux of homoserine and homoserine lactone%3B Belongs to the rht family gene gene2342 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02343 S100027_02344 S100027_02344 S100027_02344 2256926 2257111 + 30S ribosomal protein S14 type Z Metal-binding%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Zinc%3B Binds 16S rRNA%2C required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site%3B Belongs to the ribosomal protein S14P family. Zinc- binding S14P subfamily gene gene2343 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02344 S100027_02345 S100027_02345 mutT mutT 2257194 2257667 - 8-oxo-dGTP diphosphatase KEGG: pod:PODO_15870 8-oxo-dGTP diphosphatase gene gene2344 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02345 S100027_02346 S100027_02346 S100027_02346 2257861 2260527 - Pyruvate%2C water dikinase ATP-binding%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Transferase%3B Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate%3B Belongs to the PEP-utilizing enzyme family%3B KEGG: bli:BL05212 pyruvate%2C water dikinase gene gene2345 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02346 S100027_02347 S100027_02347 S100027_02347 2260800 2261405 + putative HTH-type transcriptional regulator YxbF DNA-binding%3B Repeat%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 2 HTH tetR-type DNA-binding domains gene gene2346 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02347 S100027_02348 S100027_02348 S100027_02348 2261507 2261632 + hypothetical protein gene gene2347 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02348 S100027_02349 S100027_02349 S100027_02349 2261654 2262118 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2348 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02349 S100027_02350 S100027_02350 S100027_02350 2262239 2262754 + uncharacterized protein Metal-binding%3B Belongs to the DinB family gene gene2349 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02350 S100027_02351 S100027_02351 acpD acpD 2262798 2263424 - FMN-dependent NADH-azoreductase Flavoprotein%3B FMN%3B NAD%3B Oxidoreductase%3B Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH%2C but not NADPH%2C as an electron donor for its activity%3B Belongs to the azoreductase type 1 family%3B KEGG: bli:BL01874 FMN-dependent NADH-azoreductase%3B Acting on other nitrogenous compounds as donors gene gene2350 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02351 S100027_02352 S100027_02352 S100027_02352 2263544 2264032 - General stress protein 16O Metal-binding%3B Stress response%3B Zinc%3B Zinc-finger%3B Contains 1 dksA C4-type zinc finger gene gene2351 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02352 S100027_02353 S100027_02353 S100027_02353 2264146 2264490 - uncharacterized protein gene gene2352 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02353 S100027_02354 S100027_02354 S100027_02354 2264891 2265100 - uncharacterized protein gene gene2353 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02354 S100027_02355 S100027_02355 feaB feaB 2265360 2266856 + Phenylacetaldehyde dehydrogenase NAD%3B Oxidoreductase%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: bld:BLi02249 phenylacetaldehyde dehydrogenase gene gene2354 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02355 S100027_02356 S100027_02356 S100027_02356 2266947 2268224 + putative MFS-type transporter YjbB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene2355 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02356 S100027_02357 S100027_02357 S100027_02357 2268410 2268946 - Ribosomal-protein-alanine N-acetyltransferase Acyltransferase%3B Cytoplasm%3B Transferase%3B This enzyme acetylates the N-terminal alanine of ribosomal protein S5%3B Belongs to the acetyltransferase family. RimJ subfamily%3B Contains 1 N-acetyltransferase domain%3B KEGG: bce:BC0964 ribosomal-protein-alanine N-acetyltransferase gene gene2356 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02357 S100027_02358 S100027_02358 S100027_02358 2268964 2269365 - Cytidine deaminase KEGG: psf:PSE_1583 cytidine deaminase gene gene2357 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02358 S100027_02359 S100027_02359 sqhC sqhC 2269636 2271525 + Sporulenol synthase Cell membrane%3B Lyase%3B Membrane%3B Repeat%3B Catalyzes the cyclization of tetraprenyl beta-curcumene into sporulenol%3B Belongs to the terpene cyclase/mutase family%3B Contains 3 PFTB repeats%3B KEGG: bli:BL00583 sporulenol synthase gene gene2358 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02359 S100027_02360 S100027_02360 sod2 sod2 2271522 2272367 + Superoxide dismutase Manganese%3B Metal-binding%3B Oxidoreductase%3B Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems%3B Belongs to the iron/manganese superoxide dismutase family%3B KEGG: bli:BL00582 superoxide dismutase%2C Fe-Mn family gene gene2359 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02360 S100027_02361 S100027_02361 S100027_02361 2272975 2273505 + Stress response protein YvgO Signal%3B Stress response. gene gene2360 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02361 S100027_02362 S100027_02362 S100027_02362 2273730 2275070 - putative sodium-dependent transporter Cell membrane%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Putative sodium-dependent transporter. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2. A. 22) family gene gene2361 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02362 S100027_02363 S100027_02363 S100027_02363 2275285 2276265 + putative sodium-dependent transporter YocS Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the bile acid:sodium symporter (BASS) (TC 2. A. 28) family gene gene2362 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02363 S100027_02364 S100027_02364 S100027_02364 2276295 2277575 - Dihydrolipoyllysine-residue succinyltransferase Acyltransferase%3B Lipoyl%3B Transferase%3B Tricarboxylic acid cycle%3B The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1)%2C dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: cvi:CV_1072 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) gene gene2363 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02364 S100027_02365 S100027_02365 ogdH ogdH 2277590 2280424 - Oxoglutarate dehydrogenase (succinyl-transferring) Glycolysis%3B Oxidoreductase%3B Thiamine pyrophosphate%3B The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1)%2C dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)%3B Belongs to the alpha-ketoglutarate dehydrogenase family%3B KEGG: bsu:BSU19370 2-oxoglutarate dehydrogenase E1 component gene gene2364 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02365 S100027_02366 S100027_02366 S100027_02366 2280810 2282723 - uncharacterized protein Signal%3B Contains 1 VWFA domain gene gene2365 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02366 S100027_02367 S100027_02367 S100027_02367 2282733 2283623 - uncharacterized protein ATP-binding%3B Nucleotide-binding%3B Belongs to the CbbQ/NirQ/NorQ/GpvN family gene gene2366 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02367 S100027_02368 S100027_02368 sod1 sod1 2283718 2284311 - Superoxide dismutase Cell membrane%3B Copper%3B Disulfide bond%3B Lipoprotein%3B Membrane%3B Metal-binding%3B Palmitate%3B Signal%3B Zinc%3B Belongs to the Cu-Zn superoxide dismutase family%3B KEGG: bli:BL01449 superoxide dismutase%2C Cu-Zn family gene gene2367 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02368 S100027_02369 S100027_02369 lytF lytF 2284421 2285728 - D-gamma-glutamyl-meso-diaminopimelic acid endopeptidase CwlS Cell wall biogenesis/degradation%3B Hydrolase%3B Protease%3B Repeat%3B Signal%3B Thiol protease%3B Probably functions as a cell separation enzyme in addition to LytE and LytF%3B Belongs to the peptidase C40 family%3B Contains 4 LysM repeats%3B KEGG: bsu:BSU09370 peptidoglycan endopeptidase LytF%3B Acting on peptide bonds (peptidases) gene gene2368 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02369 S100027_02370 S100027_02370 S100027_02370 2286860 2288218 + putative multidrug resistance protein NorM Antiport%3B Cell membrane%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Multidrug efflux pump%3B Belongs to the multi antimicrobial extrusion (MATE) (TC 2. A. 66. 1) family gene gene2369 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02370 S100027_02371 S100027_02371 S100027_02371 2288262 2288927 - putative N-acetyl-alpha-D-glucosaminyl L-malate deacetylase Hydrolase%3B Metal-binding%3B Zinc%3B Involved in bacillithiol (BSH) biosynthesis. Catalyzes the second step of the pathway%2C the deacetylation of N- acetylglucosaminylmalate (GlcNAc-Mal) to glucosamine malate (GlcN- Mal). Has weak activity compared with bshB1%3B Belongs to the PIGL family gene gene2370 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02371 S100027_02372 S100027_02372 S100027_02372 2288945 2289295 - uncharacterized protein gene gene2371 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02372 S100027_02373 S100027_02373 S100027_02373 2289297 2289572 - uncharacterized protein gene gene2372 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02373 S100027_02374 S100027_02374 S100027_02374 2289647 2290579 - putative transporter YojE Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene2373 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02374 S100027_02375 S100027_02375 S100027_02375 2290662 2291114 + Spore germination protein GerT Germination%3B Involved in spore germination gene gene2374 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02375 S100027_02376 S100027_02376 S100027_02376 2291067 2291162 - hypothetical protein gene gene2375 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02376 S100027_02377 S100027_02377 S100027_02377 2291343 2292041 + Cellulase Cell wall%3B Secreted%3B Signal%3B May promote colonization of plant roots. May cause loosening and extension of plant cell walls by disrupting non- covalent bonding between cellulose microfibrils and matrix glucans. Has very low expansin activity (in vitro). No enzymatic activity has been found. Binds to peptidoglycan and to plant cell walls%3B Contains 1 expansin-like EG45 domain%3B KEGG: cmi:pCM1_0020 endoglucanase gene gene2376 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02377 S100027_02378 S100027_02378 S100027_02378 2292153 2292431 - uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2377 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02378 S100027_02379 S100027_02379 S100027_02379 2292497 2293243 - 3-oxoacyl-(acyl-carrier-protein) reductase FabG Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B NADP%3B Oxidoreductase%3B Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products%2C the first reductive step in the elongation cycle of fatty acid biosynthesis%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bli:BL01442 null%3B Oxidoreductases gene gene2378 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02379 S100027_02380 S100027_02380 S100027_02380 2293249 2293569 - HTH-type transcriptional regulator YodB Activator%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Negatively regulates yodC and azoR1 which may contribute to the degradation of aromatic compounds. Probably positively regulates the catechol-specific transcription of mhqNOP%2C mhqED%2C and mhqA%3B Contains 1 HTH hxlR-type DNA-binding domain gene gene2379 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02380 S100027_02381 S100027_02381 S100027_02381 2293704 2294324 + Putative NAD(P)H nitroreductase YdgI Flavoprotein%3B FMN%3B NAD%3B NADP%3B Oxidoreductase%3B Belongs to the nitroreductase family%3B KEGG: hap:HAPS_2135 null%3B Oxidoreductases gene gene2380 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02381 S100027_02382 S100027_02382 S100027_02382 2294369 2294974 - Putative hydrolase Aromatic hydrocarbons catabolism%3B Cytoplasm%3B Detoxification%3B Hydrolase%3B Putative hydrolase that may contribute to the degradation of aromatic compounds%3B Belongs to the AB hydrolase superfamily. AB hydrolase 2 family gene gene2381 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02382 S100027_02383 S100027_02383 S100027_02383 2295339 2295542 + putative membrane protein YoyD Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2382 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02383 S100027_02384 S100027_02384 S100027_02384 2295542 2297023 + putative symporter YodF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene2383 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02384 S100027_02385 S100027_02385 S100027_02385 2297087 2297947 - putative transposase-like protein DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene2384 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02385 S100027_02386 S100027_02386 S100027_02386 2297917 2298249 - hypothetical protein gene gene2385 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02386 S100027_02387 S100027_02387 ctpA ctpA 2298356 2299753 - C-terminal processing peptidase Hydrolase%3B Protease%3B Serine protease%3B Signal%3B Belongs to the peptidase S41A family%3B Contains 1 PDZ (DHR) domain%3B KEGG: bli:BL01439 carboxyl-terminal processing protease gene gene2386 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02387 S100027_02388 S100027_02388 S100027_02388 2299913 2300623 + putative methyltransferase YodH Methyltransferase%3B Transferase%3B Belongs to the methyltransferase superfamily gene gene2387 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02388 S100027_02389 S100027_02389 S100027_02389 2300718 2300972 + uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2388 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02389 S100027_02390 S100027_02390 vanY vanY 2301008 2301829 - Serine-type D-Ala-D-Ala carboxypeptidase Carboxypeptidase%3B Cell membrane%3B Hydrolase%3B Lipoprotein%3B Membrane%3B Palmitate%3B Protease%3B Signal%3B Belongs to the peptidase M15B family%3B KEGG: bli:BL01438 D-alanyl-D-alanine carboxypeptidase gene gene2389 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02390 S100027_02391 S100027_02391 deoD deoD 2301863 2302561 - Purine-nucleoside phosphorylase Glycosyltransferase%3B Transferase%3B Belongs to the PNP/UDP phosphorylase family%3B KEGG: shp:Sput200_1676 purine-nucleoside phosphorylase gene gene2390 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02391 S100027_02392 S100027_02392 S100027_02392 2302771 2303778 + UPF0718 protein YcgR Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0718 family gene gene2391 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02392 S100027_02393 S100027_02393 S100027_02393 2303795 2304667 + hypothetical protein gene gene2392 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02393 S100027_02394 S100027_02394 S100027_02394 2304735 2304869 + uncharacterized protein gene gene2393 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02394 S100027_02395 S100027_02395 S100027_02395 2304907 2305227 - uncharacterized protein gene gene2394 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02395 S100027_02396 S100027_02396 bcrC bcrC 2305282 2306001 - Undecaprenyl-diphosphate phosphatase Cell membrane%3B Hydrolase%3B Membrane%3B Signal%3B Transmembrane%3B Transmembrane helix%3B Belongs to the PA-phosphatase related phosphoesterase family%3B KEGG: lsa:LSA1438 undecaprenyl-diphosphatase gene gene2395 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02396 S100027_02397 S100027_02397 S100027_02397 2306004 2306174 - uncharacterized protein gene gene2396 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02397 S100027_02398 S100027_02398 S100027_02398 2306297 2306431 + putative membrane protein YoyF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2397 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02398 S100027_02399 S100027_02399 S100027_02399 2306424 2307104 - uncharacterized protein gene gene2398 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02399 S100027_02400 S100027_02400 S100027_02400 2307267 2307488 - UPF0346 protein Belongs to the UPF0346 family gene gene2399 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02400 S100027_02401 S100027_02401 S100027_02401 2307594 2307875 - uncharacterized protein gene gene2400 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02401 S100027_02402 S100027_02402 kamA kamA 2307872 2309281 - Lysine 2%2C3-aminomutase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Isomerase%3B Metal-binding%3B Pyridoxal phosphate%3B S-adenosyl-L-methionine%3B Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine%3B Belongs to the radical SAM superfamily. KamA family%3B KEGG: bli:BL01430 lysine 2%2C3-aminomutase gene gene2401 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02402 S100027_02403 S100027_02403 S100027_02403 2309380 2310213 - Lysine 2%2C3-aminomutase Acyltransferase%3B Transferase%3B In vitro%2C is able to catalyze the acetylation of beta- lysine to N6-acetyl-beta-lysine%2C an archaeal osmolyte produced by methanogenic archaea. Its physiological function has not yet been elucidated%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: det:DET0221 lysine 2%2C3-aminomutase gene gene2402 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02403 S100027_02404 S100027_02404 argE argE 2310242 2311510 - Acetylornithine deacetylase Cobalt%3B Hydrolase%3B Metal-binding%3B Zinc%3B Belongs to the peptidase M20A family%3B KEGG: bsu:BSU19710 acetylornithine deacetylase gene gene2403 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02404 S100027_02405 S100027_02405 scoB scoB 2311524 2312177 - 3-oxoacid CoA-transferase Transferase%3B Belongs to the 3-oxoacid CoA-transferase subunit B family%3B KEGG: samy:DB32_004337 3-oxoacid CoA-transferase subunit B gene gene2404 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02405 S100027_02406 S100027_02406 atoD atoD 2312159 2312851 - Acetate CoA-transferase Transferase%3B Belongs to the 3-oxoacid CoA-transferase subunit A family%3B KEGG: bli:BL01426 acetate CoA/acetoacetate CoA-transferase alpha subunit gene gene2405 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02406 S100027_02407 S100027_02407 S100027_02407 2312848 2314188 - Adenosylmethionine--8-amino-7-oxononanoate transaminase Aminotransferase%3B Pyridoxal phosphate%3B Transferase%3B Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: rma:Rmag_0118 adenosylmethionine---8-amino-7-oxononanoate aminotransferase gene gene2406 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02407 S100027_02408 S100027_02408 S100027_02408 2314355 2315590 - hypothetical protein gene gene2407 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02408 S100027_02409 S100027_02409 S100027_02409 2315939 2316709 - putative N-acetyltransferase CgeE Acyltransferase%3B Transferase%3B May be involved in maturation of the outermost layer of the spore. Contains 1 N-acetyltransferase domain gene gene2408 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02409 S100027_02410 S100027_02410 msrB msrB 2316827 2317282 - Peptide-methionine (R)-S-oxide reductase Oxidoreductase%3B Belongs to the MsrB Met sulfoxide reductase family%3B KEGG: bst:GYO_2391 peptide-methionine (R)-S-oxide reductase gene gene2409 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02410 S100027_02411 S100027_02411 msrA msrA 2317269 2317814 - Peptide-methionine (S)-S-oxide reductase Oxidoreductase%3B Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine%3B Belongs to the MsrA Met sulfoxide reductase family%3B KEGG: bsu:BSU21690 peptide-methionine (S)-S-oxide reductase gene gene2410 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02411 S100027_02412 S100027_02412 S100027_02412 2318189 2318623 + putative HTH-type transcriptional regulator YpoP DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH marR-type DNA-binding domain gene gene2411 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02412 S100027_02413 S100027_02413 S100027_02413 2318689 2318940 + hypothetical protein gene gene2412 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02413 S100027_02414 S100027_02414 dge1 dge1 2319001 2320089 - Diguanylate cyclase Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Contains 1 EAL domain%3B Contains 1 GGDEF domain%3B Contains 1 MHYT domain%3B KEGG: bli:BL05221 diguanylate cyclase gene gene2413 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02414 S100027_02415 S100027_02415 S100027_02415 2320223 2321554 - putative multidrug resistance protein YpnP Antiport%3B Cell membrane%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the multi antimicrobial extrusion (MATE) (TC 2. A. 66. 1) family gene gene2414 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02415 S100027_02416 S100027_02416 S100027_02416 2321650 2322354 + hypothetical protein gene gene2415 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02416 S100027_02417 S100027_02417 S100027_02417 2322451 2322651 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2416 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02417 S100027_02418 S100027_02418 S100027_02418 2322683 2323255 - uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2417 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02418 S100027_02419 S100027_02419 S100027_02419 2323266 2324018 - uncharacterized protein gene gene2418 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02419 S100027_02420 S100027_02420 S100027_02420 2324161 2324763 - SCO1 protein like protein Cell membrane%3B Chaperone%3B Copper%3B Lipoprotein%3B Membrane%3B Metal-binding%3B Palmitate%3B Signal%3B Neccessary for insertion of copper into the active site of cytochrome c oxidase. May play a role in copper homeostasis or redox signaling%3B Belongs to the SCO1/2 family%3B Contains 1 thioredoxin domain gene gene2419 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02420 S100027_02421 S100027_02421 S100027_02421 2324760 2325602 - DegV domain-containing protein Lipid-binding%3B May bind long-chain fatty acids%2C such as palmitate%2C and may play a role in lipid transport or fatty acid metabolism%3B Contains 1 DegV domain gene gene2420 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02421 S100027_02422 S100027_02422 S100027_02422 2325750 2326001 - uncharacterized protein gene gene2421 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02422 S100027_02423 S100027_02423 ilvA ilvA 2326094 2327362 - Threonine ammonia-lyase Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Isoleucine biosynthesis%3B Lyase%3B Pyridoxal phosphate%3B Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate)%2C which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell%2C the second step is accelerated by RidA (By similarity)%3B Belongs to the serine/threonine dehydratase family%3B Contains 1 ACT-like domain%3B KEGG: bsu:BSU21770 threonine dehydratase gene gene2422 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02423 S100027_02424 S100027_02424 S100027_02424 2327596 2328597 + Psp operon transcriptional activator Activator%3B ATP-binding%3B Cytoplasm%3B DNA-binding%3B Nucleotide-binding%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Transcriptional activator for the phage shock protein (psp) operon (pspABCDE) and pspG gene%3B Contains 1 sigma-54 factor interaction domain gene gene2423 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02424 S100027_02425 S100027_02425 S100027_02425 2328613 2329254 + Hemolysin-3 like protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0073 (Hly-III) family gene gene2424 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02425 S100027_02426 S100027_02426 S100027_02426 2329295 2329918 - 1-acylglycerol-3-phosphate O-acyltransferase KEGG: bss:BSUW23_10665 1-acyl-sn-glycerol-3-phosphate acyltransferase gene gene2425 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02426 S100027_02427 S100027_02427 folA folA 2329933 2330421 - Dihydrofolate reductase Antibiotic resistance%3B Methotrexate resistance%3B NADP%3B One-carbon metabolism%3B Oxidoreductase%3B Plasmid%3B Trimethoprim resistance%3B Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis%2C and for DNA precursor synthesis (By similarity)%3B Belongs to the dihydrofolate reductase family%3B Contains 1 DHFR (dihydrofolate reductase) domain%3B KEGG: eco:b0048 dihydrofolate reductase gene gene2426 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02427 S100027_02428 S100027_02428 pgpA pgpA 2330777 2331325 - Phosphatidylglycerophosphatase To B. subtilis YutG%3B KEGG: bpu:BPUM_1917 phosphatidylglycerophosphatase A gene gene2427 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02428 S100027_02429 S100027_02429 S100027_02429 2331341 2331943 - uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2428 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02429 S100027_02430 S100027_02430 S100027_02430 2332215 2332985 - uncharacterized protein gene gene2429 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02430 S100027_02431 S100027_02431 S100027_02431 2333022 2333456 - UPF0403 protein Belongs to the UPF0403 family gene gene2430 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02431 S100027_02432 S100027_02432 ilvD ilvD 2333548 2335224 - Dihydroxy-acid dehydratase 4Fe-4S%3B Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Iron%3B Iron-sulfur%3B Lyase%3B Metal-binding%3B Belongs to the IlvD/Edd family%3B KEGG: bli:BL05225 dihydroxy-acid dehydratase gene gene2431 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02432 S100027_02433 S100027_02433 S100027_02433 2335554 2336690 - uncharacterized protein gene gene2432 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02433 S100027_02434 S100027_02434 S100027_02434 2336721 2337392 - uncharacterized protein Contains 1 HD domain gene gene2433 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02434 S100027_02435 S100027_02435 S100027_02435 2337380 2337859 - Glutathione peroxidase Abscisic acid signaling pathway%3B Mitochondrion%3B Oxidoreductase%3B Peroxidase%3B Stress response%3B Transit peptide%3B May constitute a glutathione peroxidase-like protective system against oxidative stresses. Involved positively in abscisic acid (ABA) signaling pathway that regulates numerous ABA responses%2C such as stomatal closure%2C seed germination and inhibition of vegetative growth. Oxidizes and represses target proteins (e. g. the phosphatase activity of ABI1 and ABI2) when oxidized by H(2)O(2)%2C probably after ABA signaling. Modulates the calcium channel activity in guard cells in response to ABA or H(2)O(2). Confers tolerance to drought stress%2C by enhancing the ABA-dependent stomatal closure%3B Belongs to the glutathione peroxidase family%3B KEGG: slo:Shew_2741 glutathione peroxidase gene gene2434 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02435 S100027_02436 S100027_02436 S100027_02436 2337875 2339554 - Formate--tetrahydrofolate ligase ATP-binding%3B Ligase%3B Nucleotide-binding%3B One-carbon metabolism%3B Belongs to the formate--tetrahydrofolate ligase family%3B KEGG: bli:BL01370 formate--tetrahydrofolate ligase gene gene2435 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02436 S100027_02437 S100027_02437 metA metA 2339706 2340614 + Homoserine O-succinyltransferase Acyltransferase%3B Amino-acid biosynthesis%3B Cytoplasm%3B Methionine biosynthesis%3B Transferase%3B Belongs to the HTS family%3B KEGG: bli:BL01365 homoserine O-succinyltransferase gene gene2436 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02437 S100027_02438 S100027_02438 ugtP ugtP 2340885 2342036 + 1%2C2-diacylglycerol 3-glucosyltransferase Carbohydrate metabolism%3B Cell membrane%3B Glycosyltransferase%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Transferase%3B Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG)%2C thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1%2C2-diacyl- sn-glycerol)%2C beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1->6)-D-glucopyranosyl)-1%2C2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D- glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1%2C2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)%3B Belongs to the glycosyltransferase 28 family. UgtP subfamily%3B KEGG: bsu:BSU21920 processive 1%2C2-diacylglycerol beta-glucosyltransferase gene gene2437 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02438 S100027_02439 S100027_02439 S100027_02439 2342086 2342775 - hypothetical protein gene gene2438 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02439 S100027_02440 S100027_02440 S100027_02440 2343050 2343250 + Cold shock protein CspB Activator%3B Cytoplasm%3B DNA-binding%3B Stress response%3B Transcription%3B Transcription regulation%3B Binds to the pentamer sequences ATTGG and CCAAT with highest affinity in single-stranded DNA%2C and also to other sequences. Has greater affinity for ATTGG than CCAAT. Can act as transcriptional activator of cold shock genes by recognizing putative ATTGG-box elements present in promoter regions of genes induced under cold shock conditions%3B Contains 1 CSD (cold-shock) domain gene gene2439 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02440 S100027_02441 S100027_02441 S100027_02441 2343306 2343488 - Regulatory protein DegR Transcription%3B Transcription regulation%3B Stabilizes the phosphorylated form of DegU%2C leading to enhanced production of levansucrase%2C alkaline protease%2C and neutral protease gene gene2440 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02441 S100027_02442 S100027_02442 S100027_02442 2343647 2343913 + uncharacterized protein gene gene2441 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02442 S100027_02443 S100027_02443 S100027_02443 2343997 2344182 - uncharacterized protein gene gene2442 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02443 S100027_02444 S100027_02444 rnhA rnhA 2344197 2344856 - Ribonuclease H Contains 1 RNase H domain%3B KEGG: blh:BaLi_c24240 ribonuclease HI gene gene2443 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02444 S100027_02445 S100027_02445 S100027_02445 2344932 2345633 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2444 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02445 S100027_02446 S100027_02446 S100027_02446 2345623 2346021 + Ribonuclease H Metal-binding%3B Not know%3B does not have RNase H activity. Belongs to the RNase H family. EbsB subfamily%3B Contains 1 RNase H domain%3B KEGG: bli:BL00670 ribonuclease HI gene gene2445 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02446 S100027_02447 S100027_02447 S100027_02447 2346064 2346210 + hypothetical protein gene gene2446 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02447 S100027_02448 S100027_02448 S100027_02448 2346424 2347311 - DNA-directed DNA polymerase DNA-binding%3B Exonuclease%3B Hydrolase%3B Nuclease%3B 5'-3' exonuclease acting preferentially on double- stranded DNA%3B Contains 1 5'-3' exonuclease domain%3B KEGG: lpl:lp_1508 DNA polymerase I gene gene2447 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02448 S100027_02449 S100027_02449 S100027_02449 2347396 2347545 - uncharacterized protein gene gene2448 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02449 S100027_02450 S100027_02450 S100027_02450 2347625 2347894 - uncharacterized protein gene gene2449 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02450 S100027_02451 S100027_02451 S100027_02451 2347969 2350869 - uncharacterized protein ATP-binding%3B Nucleotide-binding. gene gene2450 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02451 S100027_02452 S100027_02452 S100027_02452 2350879 2351532 - uncharacterized protein ATP-binding%3B Nucleotide-binding. gene gene2451 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02452 S100027_02453 S100027_02453 S100027_02453 2351835 2352338 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2452 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02453 S100027_02454 S100027_02454 S100027_02454 2352346 2353443 - Putative chalcone synthase Acyltransferase%3B Transferase%3B Belongs to the chalcone/stilbene synthases family gene gene2453 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02454 S100027_02455 S100027_02455 S100027_02455 2353485 2354036 - Phosphinothricin acetyltransferase KEGG: mve:X875_15470 phosphinothricin acetyltransferase gene gene2454 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02455 S100027_02456 S100027_02456 S100027_02456 2354121 2355437 - Xanthine permease Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Transport of xanthine in the cell. Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2. A. 40) subfamily gene gene2455 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02456 S100027_02457 S100027_02457 S100027_02457 2355434 2356018 - Xanthine phosphoribosyltransferase Cytoplasm%3B Glycosyltransferase%3B Purine salvage%3B Transferase%3B Converts the preformed base xanthine%2C a product of nucleic acid breakdown%2C to xanthosine 5'-monophosphate (XMP)%2C so it can be reused for RNA or DNA synthesis%3B Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily%3B KEGG: bli:BL00680 xanthine phosphoribosyltransferase gene gene2456 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02457 S100027_02458 S100027_02458 S100027_02458 2356374 2357876 - Carboxypeptidase Taq Carboxypeptidase%3B Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Zinc%3B Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus%2C including neutral%2C aromatic%2C polar and basic residues. Has lower activity with substrates ending with His or Trp%3B Belongs to the peptidase M32 family%3B KEGG: bli:BL00681 carboxypeptidase Taq gene gene2457 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02458 S100027_02459 S100027_02459 dinG dinG 2357990 2359909 - DNA helicase ATP-binding%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Belongs to the helicase family. DinG subfamily%3B Contains 1 helicase ATP-binding domain%3B KEGG: bli:BL05232 ATP-dependent DNA helicase DinG gene gene2458 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02459 S100027_02460 S100027_02460 S100027_02460 2360018 2360194 - hypothetical protein gene gene2459 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02460 S100027_02461 S100027_02461 S100027_02461 2360472 2360882 + hypothetical protein gene gene2460 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02461 S100027_02462 S100027_02462 ypsC ypsC 2361010 2362161 - Putative RNA methyltransferase YpsC Methyltransferase%3B Transferase%3B Belongs to the methyltransferase superfamily%3B Contains 1 THUMP domain%3B KEGG: bli:BL05234 putative N6-adenine-specific DNA methylase%3B Methyltransferases gene gene2461 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02462 S100027_02463 S100027_02463 S100027_02463 2362696 2362992 - Cell cycle protein GpsB Cell cycle%3B Cell division%3B Cell shape%3B Coiled coil%3B Cytoplasm%3B Divisome component that associates with the complex late in its assembly%2C after the Z-ring is formed%2C and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA%2C is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation%3B Belongs to the GpsB family gene gene2462 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02463 S100027_02464 S100027_02464 S100027_02464 2363073 2363624 - UPF0398 protein Belongs to the UPF0398 family gene gene2463 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02464 S100027_02465 S100027_02465 S100027_02465 2363740 2364009 - Spore coat protein Sporulation. gene gene2464 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02465 S100027_02466 S100027_02466 S100027_02466 2364094 2364189 - hypothetical protein gene gene2465 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02466 S100027_02467 S100027_02467 S100027_02467 2364251 2365564 - uncharacterized protein gene gene2466 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02467 S100027_02468 S100027_02468 S100027_02468 2365570 2367846 - DEAD-box ATP-dependent RNA helicase ATP-binding%3B Coiled coil%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B RNA-binding%3B Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain gene gene2467 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02468 S100027_02469 S100027_02469 S100027_02469 2367947 2368453 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cytoplasm%3B Kinase%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane%3B Contains 1 PTS EIIA type-1 domain%3B KEGG: bsu:BSU22230 PTS system%2C glucose-specific IIA component gene gene2468 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02469 S100027_02470 S100027_02470 S100027_02470 2368629 2369048 + uncharacterized protein Signal. gene gene2469 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02470 S100027_02471 S100027_02471 S100027_02471 2369067 2369510 - uncharacterized protein gene gene2470 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02471 S100027_02472 S100027_02472 S100027_02472 2369681 2369890 + uncharacterized protein gene gene2471 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02472 S100027_02473 S100027_02473 S100027_02473 2369923 2370294 - uncharacterized protein gene gene2472 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02473 S100027_02474 S100027_02474 S100027_02474 2370352 2370579 - hypothetical protein gene gene2473 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02474 S100027_02475 S100027_02475 S100027_02475 2370779 2370883 + hypothetical protein gene gene2474 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02475 S100027_02476 S100027_02476 S100027_02476 2370916 2371875 - uncharacterized protein gene gene2475 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02476 S100027_02477 S100027_02477 S100027_02477 2371929 2372525 + Holliday junction resolvase RecU Cytoplasm%3B DNA damage%3B DNA recombination%3B DNA repair%3B Endonuclease%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nuclease%3B Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands%3B Belongs to the RecU family gene gene2476 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02477 S100027_02478 S100027_02478 mrcA mrcA 2372583 2375270 + Penicillin-binding protein 1A/1B Antibiotic resistance%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Glycosyltransferase%3B Hydrolase%3B Membrane%3B Multifunctional enzyme%3B Peptidoglycan synthesis%3B Signal-anchor%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) (By similarity)%3B In the N-terminal sectio%3B belongs to the glycosyltransferase 51 family%3B In the C-terminal sectio%3B belongs to the transpeptidase family%3B Contains 1 fibronectin type-III domain%3B KEGG: bli:BL02732 penicillin-binding protein 1A%3B Hexosyltransferases gene gene2477 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02478 S100027_02479 S100027_02479 S100027_02479 2375291 2375794 - uncharacterized protein Phosphoprotein. gene gene2478 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02479 S100027_02480 S100027_02480 S100027_02480 2375791 2376453 - DNA-(apurinic or apyrimidinic site) lyase 4Fe-4S%3B DNA damage%3B DNA repair%3B DNA-binding%3B Glycosidase%3B Hydrolase%3B Iron%3B Iron-sulfur%3B Lyase%3B Metal-binding%3B DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond%2C leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination%2C leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate%3B Belongs to the Nth/MutY family%3B Contains 1 HhH domain%3B KEGG: nsa:Nitsa_1368 endonuclease III gene gene2479 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02480 S100027_02481 S100027_02481 S100027_02481 2376470 2377168 - DNA replication protein DnaD DNA replication%3B Primosome. gene gene2480 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02481 S100027_02482 S100027_02482 narS narS 2377243 2378535 - Asparagine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: bsu:BSU22360 asparaginyl-tRNA synthetase gene gene2481 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02482 S100027_02483 S100027_02483 aspB aspB 2378685 2379869 - Aspartate transaminase Aminotransferase%3B Cytoplasm%3B Pyridoxal phosphate%3B Transferase%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: woo:wOo_04400 aspartate aminotransferase gene gene2482 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02483 S100027_02484 S100027_02484 S100027_02484 2379891 2380376 - uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2483 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02484 S100027_02485 S100027_02485 S100027_02485 2380386 2380556 - uncharacterized protein gene gene2484 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02485 S100027_02486 S100027_02486 S100027_02486 2380709 2383501 - DNA helicase ATP-binding%3B DNA damage%3B DNA recombination%3B DNA repair%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Probable helicase involved in DNA repair and perhaps also replication%3B Belongs to the helicase family. DinG subfamily%3B Contains 1 exonuclease domain%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bli:BL02749 ATP-dependent DNA helicase DinG gene gene2485 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02486 S100027_02487 S100027_02487 panD panD 2383639 2384022 - Aspartate 1-decarboxylase Autocatalytic cleavage%3B Cytoplasm%3B Decarboxylase%3B Lyase%3B Pantothenate biosynthesis%3B Pyruvate%3B Schiff base%3B Zymogen%3B Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine%3B Belongs to the PanD family%3B KEGG: bli:BL02750 aspartate 1-decarboxylase gene gene2486 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02487 S100027_02488 S100027_02488 panC panC 2384022 2384888 - Pantoate--beta-alanine ligase (AMP-forming) ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Pantothenate biosynthesis%3B Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate%3B Belongs to the pantothenate synthetase family%3B KEGG: bli:BL02751 pantoate--beta-alanine ligase gene gene2487 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02488 S100027_02489 S100027_02489 panB panB 2384891 2385724 - 3-methyl-2-oxobutanoate hydroxymethyltransferase Cytoplasm%3B Magnesium%3B Metal-binding%3B Pantothenate biosynthesis%3B Transferase%3B Catalyzes the reversible reaction in which hydroxymethyl group from 5%2C10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate%3B Belongs to the PanB family%3B KEGG: bli:BL02752 3-methyl-2-oxobutanoate hydroxymethyltransferase gene gene2488 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02489 S100027_02490 S100027_02490 birA birA 2385974 2386957 - Biotin--[acetyl-CoA-carboxylase] ligase ATP-binding%3B Biotin%3B DNA-binding%3B Ligase%3B Nucleotide-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor%3B Belongs to the biotin--protein ligase family%3B Contains 1 BPL/LPL catalytic domain%3B KEGG: bli:BL02753 BirA family transcriptional regulator%2C biotin operon repressor / biotin-(acetyl-CoA-carboxylase) ligase gene gene2489 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02490 S100027_02491 S100027_02491 S100027_02491 2386942 2388135 - CCA-adding enzyme ATP-binding%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Nucleotidyltransferase%3B RNA repair%3B RNA-binding%3B Transferase%3B tRNA processing%3B Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C%2C C%2C and A to the tRNA nucleotide-73%2C using CTP and ATP as substrates and producing inorganic pyrophosphate%3B Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily%3B KEGG: bss:BSUW23_11010 tRNA nucleotidyltransferase (CCA-adding enzyme)%3B CCA tRNA nucleotidyltransferase gene gene2490 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02491 S100027_02492 S100027_02492 S100027_02492 2388095 2389276 - N-acetyl-alpha-D-glucosaminyl L-malate synthase Glycosyltransferase%3B Nucleotide-binding%3B Transferase%3B Involved in bacillithiol (BSH) biosynthesis. Catalyzes the first step of the pathway%2C the formation of N- acetylglucosaminylmalate (GlcNAc-Mal) from UDP-N-acetylglucosamine (UDP-GlcNAc) and L-malate%3B Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: saa:SAUSA300_1349 null%3B Hexosyltransferases gene gene2491 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02492 S100027_02493 S100027_02493 S100027_02493 2389276 2390013 - N-acetyl-alpha-D-glucosaminyl L-malate deacetylase Hydrolase%3B Metal-binding%3B Zinc%3B Involved in bacillithiol (BSH) biosynthesis. Catalyzes the second step of the pathway%2C the deacetylation of N- acetylglucosaminylmalate (GlcNAc-Mal) to glucosamine malate (GlcN- Mal)%3B Belongs to the PIGL family gene gene2492 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02493 S100027_02494 S100027_02494 mgsA mgsA 2389970 2390383 - Methylglyoxal synthase Lyase%3B Belongs to the methylglyoxal synthase family%3B KEGG: amc:MADE_1002670 methylglyoxal synthase gene gene2493 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02494 S100027_02495 S100027_02495 dapB dapB 2390403 2391206 - 4-hydroxy-tetrahydrodipicolinate reductase Amino-acid biosynthesis%3B Cytoplasm%3B Diaminopimelate biosynthesis%3B Lysine biosynthesis%3B NAD%3B NADP%3B Oxidoreductase%3B Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate%3B Belongs to the DapB family%3B KEGG: bli:BL02758 4-hydroxy-tetrahydrodipicolinate reductase gene gene2494 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02495 S100027_02496 S100027_02496 aroA aroA 2391219 2391557 - 3-phosphoshikimate 1-carboxyvinyltransferase KEGG: eao:BD94_0226 3-phosphoshikimate 1-carboxyvinyltransferase gene gene2495 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02496 S100027_02497 S100027_02497 S100027_02497 2391695 2392567 + UPF0750 membrane protein YpjC Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0750 family gene gene2496 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02497 S100027_02498 S100027_02498 S100027_02498 2392610 2393410 - uncharacterized protein Membrane%3B Signal%3B Transmembrane%3B Transmembrane helix. gene gene2497 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02498 S100027_02499 S100027_02499 S100027_02499 2393485 2394069 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2498 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02499 S100027_02500 S100027_02500 S100027_02500 2394307 2395074 - Menaquinol-cytochrome c reductase cytochrome b/c subunit Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Component of the menaquinol-cytochrome c reductase complex. Belongs to the cytochrome b family%3B Contains 1 cytochrome c domain gene gene2499 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02500 S100027_02501 S100027_02501 S100027_02501 2395107 2395781 - Menaquinol-cytochrome c reductase cytochrome b subunit Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Component of the menaquinol-cytochrome c reductase complex. Belongs to the cytochrome b family gene gene2500 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02501 S100027_02502 S100027_02502 qcrA qcrA 2395784 2396290 - Menaquinol-cytochrome c reductase iron-sulfur subunit 2Fe-2S%3B Disulfide bond%3B Electron transport%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase%3B Transport%3B Component of the menaquinol-cytochrome c reductase complex. The Rieske protein is a high potential 2Fe-2S protein. Contains 1 Rieske domain%3B KEGG: bli:BL02762 menaquinol-cytochrome c reductase iron-sulfur subunit%3B With a cytochrome as acceptor gene gene2501 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02502 S100027_02503 S100027_02503 S100027_02503 2396437 2396883 - uncharacterized protein gene gene2502 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02503 S100027_02504 S100027_02504 S100027_02504 2396965 2397504 - UPF0302 protein Belongs to the UPF0302 family gene gene2503 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02504 S100027_02505 S100027_02505 S100027_02505 2397573 2398847 - TPR repeat-containing protein YpiA Repeat%3B TPR repeat%3B Contains 9 TPR repeats gene gene2504 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02505 S100027_02506 S100027_02506 S100027_02506 2399081 2400367 - 3-phosphoshikimate 1-carboxyvinyltransferase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Cytoplasm%3B Transferase%3B Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate%3B Belongs to the EPSP synthase family%3B KEGG: bli:BL02766 3-phosphoshikimate 1-carboxyvinyltransferase gene gene2505 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02506 S100027_02507 S100027_02507 S100027_02507 2400378 2401493 - Prephenate dehydrogenase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B NAD%3B Oxidoreductase%3B Tyrosine biosynthesis%3B Contains 1 ACT domain%3B Contains 1 prephenate/arogenate dehydrogenase domain%3B KEGG: bli:BL02768 prephenate dehydrogenase gene gene2506 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02507 S100027_02508 S100027_02508 hisC hisC 2401547 2402632 - Histidinol-phosphate transaminase Amino-acid biosynthesis%3B Aminotransferase%3B Histidine biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily%3B KEGG: bld:BLi02397 histidinol-phosphate aminotransferase gene gene2507 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02508 S100027_02509 S100027_02509 trpA trpA 2402642 2403445 - Tryptophan synthase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Lyase%3B Tryptophan biosynthesis%3B The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate%3B Belongs to the TrpA family%3B KEGG: bli:BL02770 tryptophan synthase alpha chain%3B overlaps another CDS with the same product name gene gene2508 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02509 S100027_02510 S100027_02510 trpB trpB 2403414 2404640 - Tryptophan synthase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Lyase%3B Pyridoxal phosphate%3B Tryptophan biosynthesis%3B The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine%3B Belongs to the TrpB family%3B KEGG: bli:BL02771 tryptophan synthase beta chain%3B overlaps another CDS with the same product name gene gene2509 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02510 S100027_02511 S100027_02511 trpF trpF 2404621 2405277 - Phosphoribosylanthranilate isomerase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Isomerase%3B Tryptophan biosynthesis%3B Belongs to the TrpF family%3B KEGG: bsr:I33_2325 phosphoribosylanthranilate isomerase gene gene2510 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02511 S100027_02512 S100027_02512 trpC trpC 2405277 2406035 - Indole-3-glycerol-phosphate synthase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Decarboxylase%3B Lyase%3B Tryptophan biosynthesis%3B Belongs to the TrpC family%3B KEGG: bli:BL02773 indole-3-glycerol phosphate synthase gene gene2511 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02512 S100027_02513 S100027_02513 trpD trpD 2406028 2407044 - Anthranilate phosphoribosyltransferase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Glycosyltransferase%3B Magnesium%3B Metal-binding%3B Transferase%3B Tryptophan biosynthesis%3B Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)%3B Belongs to the anthranilate phosphoribosyltransferase family%3B KEGG: bli:BL02774 anthranilate phosphoribosyltransferase gene gene2512 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02513 S100027_02514 S100027_02514 trpE trpE 2407016 2408563 - Anthranilate synthase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Lyase%3B Magnesium%3B Metal-binding%3B Tryptophan biosynthesis%3B Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate%2C an intermediate in the biosynthesis of L-tryptophan. In the first step%2C the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that%2C along with chorismate%2C is used in the second step%2C catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG%2C TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity)%3B Belongs to the anthranilate synthase component I family%3B KEGG: bli:BL02775 anthranilate synthase component I gene gene2513 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02514 S100027_02515 S100027_02515 aroH aroH 2408809 2409192 - Chorismate mutase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Cytoplasm%3B Isomerase%3B Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis%3B Contains 1 chorismate mutase aroH-type domain%3B KEGG: bsu:BSU22690 chorismate mutase gene gene2514 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02515 S100027_02516 S100027_02516 aroB aroB 2409189 2410277 - 3-dehydroquinate synthase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Cobalt%3B Cytoplasm%3B Lyase%3B NAD%3B Zinc%3B Belongs to the dehydroquinate synthase family%3B KEGG: bli:BL02777 3-dehydroquinate synthase gene gene2515 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02516 S100027_02517 S100027_02517 aroC aroC 2410277 2411449 - Chorismate synthase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B FAD%3B Flavoprotein%3B FMN%3B Lyase%3B NADP%3B Catalyzes the anti-1%2C4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate%2C which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system%3B Belongs to the chorismate synthase family%3B KEGG: gsu:GSU2027 chorismate synthase gene gene2516 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02517 S100027_02518 S100027_02518 cheR cheR 2411521 2412288 - Protein-glutamate O-methyltransferase Chemotaxis%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. CheR is responsible for the chemotactic adaptation to repellents. Contains 1 cheR-type methyltransferase domain%3B KEGG: bli:BL02780 chemotaxis protein methyltransferase CheR gene gene2517 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02518 S100027_02519 S100027_02519 S100027_02519 2412428 2412874 - Nucleoside-diphosphate kinase ATP-binding%3B Cytoplasm%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide metabolism%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism%2C using a phosphorylated active-site intermediate%3B Belongs to the NDK family%3B KEGG: eco:b2518 nucleoside-diphosphate kinase gene gene2518 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02519 S100027_02520 S100027_02520 S100027_02520 2412999 2413961 - Heptaprenyl diphosphate synthase Isoprene biosynthesis%3B Magnesium%3B Metal-binding%3B Sporulation%3B Transferase%3B Supplies heptaprenyl diphosphate%2C the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7)%3B Belongs to the FPP/GGPP synthase family%3B KEGG: bli:BL02782 heptaprenyl diphosphate synthase gene gene2519 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02520 S100027_02521 S100027_02521 ubiE ubiE 2413991 2414689 - Demethylmenaquinone methyltransferase Menaquinone biosynthesis%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family%3B KEGG: bsu:BSU22750 demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1%2C4-benzoquinol methylase gene gene2520 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02521 S100027_02522 S100027_02522 S100027_02522 2414692 2415477 - Heptaprenyl diphosphate synthase Isoprene biosynthesis%3B Sporulation%3B Transferase%3B Supplies heptaprenyl diphosphate%2C the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7)%3B KEGG: blh:BaLi_c25000 heptaprenyl diphosphate synthase gene gene2521 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02522 S100027_02523 S100027_02523 S100027_02523 2415611 2415847 - Transcription attenuation protein MtrB RNA-binding%3B Transcription%3B Transcription regulation%3B Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan%3B Belongs to the MtrB family gene gene2522 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02523 S100027_02524 S100027_02524 gch1 gch1 2415869 2416438 - GTP cyclohydrolase I GTP-binding%3B Hydrolase%3B Metal-binding%3B Nucleotide-binding%3B One-carbon metabolism%3B Zinc%3B Belongs to the GTP cyclohydrolase I family%3B KEGG: bsu:BSU22780 GTP cyclohydrolase I gene gene2523 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02524 S100027_02525 S100027_02525 S100027_02525 2416645 2416923 - DNA-binding protein HU-1 DNA condensation%3B DNA-binding%3B Phosphoprotein%3B Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it%2C and thus to prevent its denaturation under extreme environmental conditions%3B Belongs to the bacterial histone-like protein family gene gene2524 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02525 S100027_02526 S100027_02526 S100027_02526 2417341 2418819 - Stage IV sporulation protein ATP-binding%3B Cytoplasm%3B Hydrolase%3B Nucleotide-binding%3B Sporulation%3B ATPase. Has a role at an early stage in the morphogenesis of the spore coat outer layers. Directs the assembly of the coat and exosporium to an area around the forespore gene gene2525 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02526 S100027_02527 S100027_02527 S100027_02527 2419021 2419737 - uncharacterized protein gene gene2526 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02527 S100027_02528 S100027_02528 S100027_02528 2419760 2419963 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2527 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02528 S100027_02529 S100027_02529 gpsA gpsA 2420291 2421331 - Glycerol-3-phosphate dehydrogenase (NAD(P)(+)) Cytoplasm%3B Lipid biosynthesis%3B Lipid metabolism%3B NAD%3B Oxidoreductase%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family%3B KEGG: mmn:midi_00920 glycerol-3-phosphate dehydrogenase (NAD(P)+) gene gene2528 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02529 S100027_02530 S100027_02530 S100027_02530 2421347 2422657 - GTPase Der GTP-binding%3B Nucleotide-binding%3B Repeat%3B Ribosome biogenesis%3B GTPase that plays an essential role in the late steps of ribosome biogenesis%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. EngA (Der) GTPase family%3B Contains 2 EngA-type G (guanine nucleotide-binding) domains%3B Contains 1 KH-like domain gene gene2529 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02530 S100027_02531 S100027_02531 S100027_02531 2422820 2423014 - uncharacterized protein overlaps another CDS with the same product name gene gene2530 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02531 S100027_02532 S100027_02532 S100027_02532 2423011 2423910 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B overlaps another CDS with the same product name gene gene2531 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02532 S100027_02533 S100027_02533 S100027_02533 2423907 2424509 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B overlaps another CDS with the same product name gene gene2532 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02533 S100027_02534 S100027_02534 S100027_02534 2424582 2424713 + uncharacterized protein gene gene2533 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02534 S100027_02535 S100027_02535 S100027_02535 2424743 2425798 - Isopentenyl-diphosphate Delta-isomerase Cytoplasm%3B Flavoprotein%3B FMN%3B Isomerase%3B Isoprene biosynthesis%3B Magnesium%3B Metal-binding%3B NADP%3B Involved in the biosynthesis of isoprenoids. Catalyzes the 1%2C3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer%2C dimethylallyl diphosphate (DMAPP)%3B Belongs to the IPP isomerase type 2 family%3B KEGG: bli:BL02217 isopentenyl-diphosphate delta-isomerase gene gene2534 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02535 S100027_02536 S100027_02536 S100027_02536 2425808 2426956 - 30S ribosomal protein S1 like protein Phosphoprotein%3B Repeat%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B Plays a role in sporulation%3B Belongs to the ribosomal protein S1P family%3B Contains 4 S1 motif domains gene gene2535 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02536 S100027_02537 S100027_02537 S100027_02537 2427174 2427854 - UMP/CMP kinase ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the cytidylate kinase family. Type 1 subfamily%3B KEGG: gxy:GLX_11090 cytidylate kinase gene gene2536 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02537 S100027_02538 S100027_02538 S100027_02538 2427934 2428110 - uncharacterized protein gene gene2537 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02538 S100027_02539 S100027_02539 S100027_02539 2428272 2429624 - Sporulation protein YpeB Germination%3B Sporulation%3B Required for spore cortex hydrolysis during germination. Appears to be required for either expression%2C localization%2C activation or function of SleB. Belongs to the YpeB family gene gene2538 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02539 S100027_02540 S100027_02540 S100027_02540 2429641 2430606 - N-acetylmuramoyl-L-alanine amidase Cell wall biogenesis/degradation%3B Germination%3B Hydrolase%3B Signal%3B Sporulation%3B Required for spore cortex hydrolysis during germination%3B Belongs to the SleB family%3B KEGG: bli:BL02222 N-acetylmuramoyl-L-alanine amidase gene gene2539 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02540 S100027_02541 S100027_02541 S100027_02541 2430745 2431413 - Protease PrsW Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Involved in the degradation of specific anti-sigma factors. Responsible for Site-1 cleavage of the RsiW anti-sigma factor. This results%2C after two other proteolytic steps catalyzed by the RasP and ClpXP proteases%2C in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity)%3B Belongs to the protease PrsW family gene gene2540 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02541 S100027_02542 S100027_02542 ansA ansA 2431493 2432461 - Asparaginase Cytoplasm%3B Hydrolase%3B Belongs to the asparaginase 1 family%3B Contains 1 asparaginase/glutaminase domain%3B KEGG: bli:BL02224 L-asparaginase gene gene2541 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02542 S100027_02543 S100027_02543 S100027_02543 2432571 2433566 - Thioredoxin-disulfide reductase KEGG: bld:BLi02434 thioredoxin reductase (NADPH) gene gene2542 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02543 S100027_02544 S100027_02544 gudB gudB 2433626 2434900 - Glutamate dehydrogenase NAD%3B Oxidoreductase%3B GudB seems to be intrinsically inactive%2C however spontaneous mutations removing a 9-bp direct repeat within the wild-type gudB sequence activated the GudB protein and allowed more-efficient utilization of amino acids of the glutamate family. This insertion presumably causes severe destabilization of the fold of the protein%2C leading to an inactive enzyme that is very quickly degraded. The cryptic GudB serves as a buffer that may compensate for mutations in the rocG gene and that can also be decryptified for the utilization of glutamate as a single carbon source in the absence of arginine. It is unable to synthesize glutamate%3B Belongs to the Glu/Leu/Phe/Val dehydrogenases family%3B KEGG: bli:BL02226 glutamate dehydrogenase gene gene2543 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02544 S100027_02545 S100027_02545 S100027_02545 2435096 2435680 - Adapter protein MecA Competence%3B Sporulation%3B Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed%2C inhibits sporulation. Also involved in Spx degradation by ClpC (By similarity)%3B Belongs to the MecA family gene gene2544 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02545 S100027_02546 S100027_02546 S100027_02546 2435834 2436619 - uncharacterized protein ATP-binding%3B Nucleotide-binding%3B Signal. gene gene2545 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02546 S100027_02547 S100027_02547 S100027_02547 2436698 2437150 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2546 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02547 S100027_02548 S100027_02548 S100027_02548 2437209 2437988 - uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix%3B overlaps another CDS with the same product name gene gene2547 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02548 S100027_02549 S100027_02549 S100027_02549 2437930 2438574 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B overlaps another CDS with the same product name gene gene2548 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02549 S100027_02550 S100027_02550 S100027_02550 2438568 2440064 - DNA helicase ATP-binding%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B DNA helicase%3B Belongs to the helicase family. RecQ subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bli:BL02232 ATP-dependent DNA helicase RecQ%3B overlaps another CDS with the same product name gene gene2549 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02550 S100027_02551 S100027_02551 S100027_02551 2440057 2441151 - DNA helicase KEGG: drm:Dred_1261 ATP-dependent DNA helicase RecQ%3B overlaps another CDS with the same product name gene gene2550 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02551 S100027_02552 S100027_02552 S100027_02552 2441379 2441627 + Ferredoxin 4Fe-4S%3B Electron transport%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Repeat%3B Transport%3B Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. This ferredoxin may act as a phosphodonor to cytochrome P450 BioI%3B Contains 1 4Fe-4S ferredoxin-type domain gene gene2551 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02552 S100027_02553 S100027_02553 S100027_02553 2441781 2442359 - Riboflavin transporter FmnP Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mediates uptake of riboflavin and roseoflavin%2C a toxic riboflavin analo%3B may also transport FMN. Probably a riboflavin- binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane%2C not extracytoplasmic soluble proteins (By similarity)%3B Belongs to the prokaryotic riboflavin transporter (P- RFT) (TC 2. A. 87) family gene gene2552 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02553 S100027_02554 S100027_02554 serA serA 2442902 2444479 + Phosphoglycerate dehydrogenase Amino-acid biosynthesis%3B NAD%3B Oxidoreductase%3B Serine biosynthesis%3B Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU23070 D-3-phosphoglycerate dehydrogenase gene gene2553 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02554 S100027_02555 S100027_02555 lytM lytM 2444528 2445352 - Lysostaphin Cell membrane%3B Hydrolase%3B Membrane%3B Metal-binding%3B Metalloprotease%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Zinc%3B Belongs to the peptidase M23B family%3B KEGG: har:HEAR2799 lysostaphin gene gene2554 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02555 S100027_02556 S100027_02556 S100027_02556 2445477 2446403 - Sigma-X negative effector Cell membrane%3B Membrane%3B Repressor%3B Transcription%3B Transcription regulation. gene gene2555 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02556 S100027_02557 S100027_02557 S100027_02557 2446519 2447103 - RNA polymerase sigma factor SigX Cell membrane%3B DNA-binding%3B Membrane%3B Sigma factor%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. May be involved in the regulation of iron metabolism. Belongs to the sigma-70 factor family. ECF subfamily gene gene2556 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02557 S100027_02558 S100027_02558 S100027_02558 2447378 2448292 - Transcriptional regulator LytR Cell membrane%3B Membrane%3B Signal-anchor%3B Transcription%3B Transcription regulation%3B Transmembrane%3B Transmembrane helix%3B Attenuator role for operon expression%3B Belongs to the LytR/CpsA/Psr regulatory protein family gene gene2557 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02558 S100027_02559 S100027_02559 S100027_02559 2448502 2449068 - Chitooligosaccharide deacetylase Cytoplasm%3B Hydrolase%3B Metal-binding%3B Nodulation%3B Is involved in generating a small heat-stable compound (Nod)%2C an acylated oligomer of N-acetylglucosamine%2C that stimulates mitosis in various plant protoplasts. Belongs to the polysaccharide deacetylase family%3B KEGG: rho:RHOM_06145 peptidoglycan-N-acetylmuramic acid deacetylase%3B In linear amides gene gene2558 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02559 S100027_02560 S100027_02560 S100027_02560 2449489 2450622 - hypothetical protein gene gene2559 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02560 S100027_02561 S100027_02561 S100027_02561 2450619 2452070 - Sensor protein VanSB Antibiotic resistance%3B ATP-binding%3B Cell membrane%3B Cell wall biogenesis/degradation%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system VanS/VanR. Activates the transcription of vanH%2C vanA and vanX in response to vancomycin which results in vancomycin resistance. VanS activates VanR by phosphorylation. Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: gme:Gmet_2737 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene2560 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02561 S100027_02562 S100027_02562 S100027_02562 2452074 2452775 - Transcriptional regulatory protein ResD Activator%3B Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system ResD/ResE. Required for the expression of resA%2C ctaA%2C qcrABC and fn%3B activation role in global regulation of aerobic and anaerobic respiration%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2561 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02562 S100027_02563 S100027_02563 S100027_02563 2453228 2455009 - Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system ResD/ResE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates ResD%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bsu:BSU23110 two-component system%2C OmpR family%2C sensor histidine kinase ResE gene gene2562 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02563 S100027_02564 S100027_02564 S100027_02564 2455006 2455728 - Transcriptional regulatory protein ResD Activator%3B Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system ResD/ResE. Required for the expression of resA%2C ctaA%2C qcrABC and fn%3B activation role in global regulation of aerobic and anaerobic respiration%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2563 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02564 S100027_02565 S100027_02565 S100027_02565 2455873 2457048 - Cytochrome c bioproteinis protein ResC Cell membrane%3B Cytochrome c-type biogenesis%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Required for the biogenesis of c-type cytochromes%3B Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family gene gene2564 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02565 S100027_02566 S100027_02566 S100027_02566 2457074 2458705 - Cytochrome c bioproteinis protein ResB Cell membrane%3B Cytochrome c-type biogenesis%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Required for the biogenesis of c-type cytochromes gene gene2565 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02566 S100027_02567 S100027_02567 S100027_02567 2458702 2459235 - Thiol-disulfide oxidoreductase ResA Cell membrane%3B Cytochrome c-type biogenesis%3B Disulfide bond%3B Membrane%3B Oxidoreductase%3B Redox-active center%3B Signal-anchor%3B Transmembrane%3B Transmembrane helix%3B Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA%2C leading to breakage of disulfide bonds in apocytochrome%3B following this reduction heme can be covalently attached%3B Belongs to the thioredoxin family. ResA subfamily%3B Contains 1 thioredoxin domain gene gene2566 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02567 S100027_02568 S100027_02568 rluB rluB 2459323 2460057 - 23S rRNA pseudouridine(2605) synthase Isomerase%3B RNA-binding%3B rRNA processing%3B Responsible for synthesis of pseudouridine from uracil- 2633 in 23S ribosomal RNA. Belongs to the pseudouridine synthase RsuA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: sdl:Sdel_0065 23S rRNA pseudouridine2605 synthase gene gene2567 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02568 S100027_02569 S100027_02569 S100027_02569 2460216 2460752 - Spore maturation protein Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Involved in spore core dehydratio%3B might be involved in the transport of something into or out of the forespore or could be required for some modification of the cortex peptidoglycan structure. Belongs to the SpmB family gene gene2568 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02569 S100027_02570 S100027_02570 S100027_02570 2460757 2461344 - Spore maturation protein Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix. gene gene2569 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02570 S100027_02571 S100027_02571 S100027_02571 2461332 2462486 - Serine-type D-Ala-D-Ala carboxypeptidase Carboxypeptidase%3B Cell shape%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Membrane%3B Peptidoglycan synthesis%3B Protease%3B Signal%3B Sporulation%3B Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. Required specifically for the synthesis of the spore form of peptidoglycan (cortex). Belongs to the peptidase S11 family%3B KEGG: bli:BL01881 D-alanyl-D-alanine carboxypeptidase gene gene2570 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02571 S100027_02572 S100027_02572 S100027_02572 2462639 2463130 - uncharacterized protein gene gene2571 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02572 S100027_02573 S100027_02573 S100027_02573 2463245 2463838 - Segregation and condensation protein Cell cycle%3B Cell division%3B Chromosome partition%3B Cytoplasm%3B Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves%3B Belongs to the ScpB family%3B overlaps another CDS with the same product name gene gene2572 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02573 S100027_02574 S100027_02574 S100027_02574 2463828 2464583 - Segregation and condensation protein Cell cycle%3B Cell division%3B Chromosome partition%3B Cytoplasm%3B Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves%3B Belongs to the ScpA family%3B overlaps another CDS with the same product name gene gene2573 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02574 S100027_02575 S100027_02575 S100027_02575 2464766 2464861 + hypothetical protein gene gene2574 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02575 S100027_02576 S100027_02576 S100027_02576 2464982 2465503 + uncharacterized protein gene gene2575 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02576 S100027_02577 S100027_02577 S100027_02577 2465514 2465888 - Protein RibT Acyltransferase%3B Riboflavin biosynthesis%3B Transferase%3B Involved in riboflavin biosynthesis. Contains 1 N-acetyltransferase domain gene gene2576 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02577 S100027_02578 S100027_02578 ribH ribH 2465990 2466454 - 6%2C7-dimethyl-8-ribityllumazine synthase Riboflavin biosynthesis%3B Transferase%3B Catalyzes the formation of 6%2C7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3%2C4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin%3B Belongs to the DMRL synthase family%3B KEGG: bli:BL01888 6%2C7-dimethyl-8-ribityllumazine synthase gene gene2577 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02578 S100027_02579 S100027_02579 S100027_02579 2466489 2467685 - 3%2C4-dihydroxy-2-butanone-4-phosphate synthase GTP-binding%3B Hydrolase%3B Lyase%3B Magnesium%3B Manganese%3B Metal-binding%3B Multifunctional enzyme%3B Nucleotide-binding%3B Riboflavin biosynthesis%3B Zinc%3B Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3%2C4-dihydroxy-2-butanone 4-phosphate%3B Catalyzes the conversion of GTP to 2%2C5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP)%2C formate and pyrophosphate%3B In the N-terminal sectio%3B belongs to the DHBP synthase family%3B In the C-terminal sectio%3B belongs to the GTP cyclohydrolase II family%3B KEGG: bid:Bind_0944 3%2C4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II gene gene2578 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02579 S100027_02580 S100027_02580 ribE ribE 2467707 2468354 - Riboflavin synthase Repeat%3B Riboflavin biosynthesis%3B Transferase%3B Catalyzes the dismutation of two molecules of 6%2C7- dimethyl-8-ribityllumazine%2C resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil%3B Contains 2 lumazine-binding repeats%3B KEGG: hdu:HD1162 riboflavin synthase gene gene2579 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02580 S100027_02581 S100027_02581 ribD ribD 2468366 2469454 - Diaminohydroxyphosphoribosylaminopyrimidine deaminase Hydrolase%3B Metal-binding%3B Multifunctional enzyme%3B NADP%3B Oxidoreductase%3B Riboflavin biosynthesis%3B Zinc%3B Converts 2%2C5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2%2C4(1h%2C3h)- pyrimidinedione 5'-phosphate. In the N-terminal sectio%3B belongs to the cytidine and deoxycytidylate deaminase family%3B In the C-terminal sectio%3B belongs to the HTP reductase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: bli:BL01891 diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase gene gene2580 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02581 S100027_02582 S100027_02582 S100027_02582 2469815 2470159 - uncharacterized protein gene gene2581 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02582 S100027_02583 S100027_02583 S100027_02583 2470422 2472608 - 2'%2C3'-cyclic-nucleotide 3'-phosphodiesterase KEGG: fnu:FN1603 2'%2C3'-cyclic-nucleotide 3'-phosphodiesterase gene gene2582 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02583 S100027_02584 S100027_02584 S100027_02584 2472735 2473172 - Small heat shock protein C2 Stress response%3B Belongs to the small heat shock protein (HSP20) family gene gene2583 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02584 S100027_02585 S100027_02585 S100027_02585 2473331 2473636 - hypothetical protein gene gene2584 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02585 S100027_02586 S100027_02586 rapA rapA 2473626 2474756 - Response regulator aspartate phosphatase Hydrolase%3B Protein phosphatase%3B Repeat%3B TPR repeat%3B Belongs to the RAP family%3B Contains 5 TPR repeats%3B KEGG: bli:BL05244 response regulator aspartate phosphatase A (stage 0 sporulation protein L)%3B Acting on ester bonds gene gene2585 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02586 S100027_02587 S100027_02587 ppiB ppiB 2474987 2475424 - Peptidylprolyl isomerase Cytoplasm%3B Isomerase%3B Rotamase%3B PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Belongs to the cyclophilin-type PPIase family%3B Contains 1 PPIase cyclophilin-type domain%3B KEGG: bli:BL05245 peptidyl-prolyl cis-trans isomerase B (cyclophilin B) gene gene2586 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02587 S100027_02588 S100027_02588 S100027_02588 2475761 2476657 + uncharacterized protein gene gene2587 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02588 S100027_02589 S100027_02589 S100027_02589 2476654 2477514 - UPF0714 protein YndL Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0714 family gene gene2588 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02589 S100027_02590 S100027_02590 lysA lysA 2477753 2479072 - Diaminopimelate decarboxylase Amino-acid biosynthesis%3B Decarboxylase%3B Lyase%3B Lysine biosynthesis%3B Pyridoxal phosphate%3B Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine%3B Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily%3B KEGG: bsu:BSU23380 diaminopimelate decarboxylase gene gene2589 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02590 S100027_02591 S100027_02591 S100027_02591 2479436 2479765 + hypothetical protein gene gene2590 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02591 S100027_02592 S100027_02592 S100027_02592 2479810 2481282 - Stage V sporulation protein AF Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Belongs to the GerABKA family gene gene2591 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02592 S100027_02593 S100027_02593 S100027_02593 2481242 2481844 - Stage V sporulation protein AE Sporulation. gene gene2592 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02593 S100027_02594 S100027_02594 S100027_02594 2481851 2482201 - Stage V sporulation protein AEB Sporulation. gene gene2593 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02594 S100027_02595 S100027_02595 S100027_02595 2482203 2483222 - Stage V sporulation protein AD Sporulation. gene gene2594 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02595 S100027_02596 S100027_02596 S100027_02596 2483235 2483684 - Stage V sporulation protein AC Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix. gene gene2595 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02596 S100027_02597 S100027_02597 S100027_02597 2483698 2484123 - Stage V sporulation protein Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix. gene gene2596 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02597 S100027_02598 S100027_02598 S100027_02598 2484113 2484733 - Stage V sporulation protein AA Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix. gene gene2597 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02598 S100027_02599 S100027_02599 S100027_02599 2484901 2485668 - RNA polymerase sigma-F factor DNA-binding%3B Sigma factor%3B Sporulation%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes. Belongs to the sigma-70 factor family gene gene2598 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02599 S100027_02600 S100027_02600 S100027_02600 2485681 2486121 - Non-specific serine/threonine protein kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Serine/threonine-protein kinase%3B Sporulation%3B Transferase%3B Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition%3B Belongs to the anti-sigma-factor family%3B KEGG: bsu:BSU23460 stage II sporulation protein AB (anti-sigma F factor) gene gene2599 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02600 S100027_02601 S100027_02601 S100027_02601 2486118 2486471 - Anti-sigma F factor antagonist Phosphoprotein%3B Sporulation%3B In the phosphorylated form it could act as an anti-anti- sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition%3B Belongs to the anti-sigma-factor antagonist family%3B Contains 1 STAS domain gene gene2600 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02601 S100027_02602 S100027_02602 S100027_02602 2486565 2487737 - Serine-type D-Ala-D-Ala carboxypeptidase Carboxypeptidase%3B Cell shape%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Peptidoglycan synthesis%3B Protease%3B Secreted%3B Signal%3B Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. Belongs to the peptidase S11 family%3B KEGG: bli:BL00775 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6) gene gene2601 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02602 S100027_02603 S100027_02603 punA punA 2487895 2488710 - Purine-nucleoside phosphorylase Glycosyltransferase%3B Phosphoprotein%3B Transferase%3B The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules%2C with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine%2C inosine%2C 2'-deoxyguanosine and 2'-deoxyinosine%3B Belongs to the PNP/MTAP phosphorylase family%3B KEGG: bli:BL00774 purine-nucleoside phosphorylase gene gene2602 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02603 S100027_02604 S100027_02604 S100027_02604 2488722 2489906 - Phosphopentomutase Cytoplasm%3B Isomerase%3B Manganese%3B Metal-binding%3B Phosphotransfer between the C1 and C5 carbon atoms of pentose%3B Belongs to the phosphopentomutase family%3B KEGG: bli:BL00772 phosphopentomutase gene gene2603 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02604 S100027_02605 S100027_02605 S100027_02605 2490100 2490990 - Tyrosine recombinase XerD Cell cycle%3B Cell division%3B Chromosome partition%3B Cytoplasm%3B DNA integration%3B DNA recombination%3B DNA-binding%3B Site-specific tyrosine recombinase%2C which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids%3B Belongs to the 'phage' integrase family. XerD subfamily gene gene2604 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02605 S100027_02606 S100027_02606 S100027_02606 2490997 2491221 - putative membrane protein YqzK Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2605 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02606 S100027_02607 S100027_02607 S100027_02607 2491342 2491791 - Ferric uptake regulation protein Cytoplasm%3B DNA-binding%3B Iron%3B Metal-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Zinc%3B Iron uptake repressor. Acts on the transcription of ferri-siderophore uptake genes. Belongs to the Fur family gene gene2606 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02607 S100027_02608 S100027_02608 S100027_02608 2491910 2492566 - Stage II sporulation protein Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane gene gene2607 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02608 S100027_02609 S100027_02609 S100027_02609 2492680 2494026 - Cellobiose permease IIC component Cell membrane%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in cellobiose transport. Contains 1 PTS EIIC type-3 domain gene gene2608 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02609 S100027_02610 S100027_02610 S100027_02610 2494046 2494345 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cytoplasm%3B Kinase%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in cellobiose transport. Contains 1 PTS EIIB type-3 domain%3B KEGG: eoj:ECO26_2139 PTS system%2C cellobiose-specific IIB component gene gene2609 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02610 S100027_02611 S100027_02611 S100027_02611 2494610 2495533 + Nicotinamide riboside transporter Cell membrane%3B Membrane%3B Phosphoprotein%3B Transmembrane%3B Transmembrane helix%3B Transport%3B High-affinity pH-dependent nicotinamide riboside transporter which also transports thiamine with low affinity. Involved in 5-fluorocytosine sensitivity%3B Belongs to the purine-cytosine permease (2. A. 39) family gene gene2610 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02611 S100027_02612 S100027_02612 S100027_02612 2495494 2496084 + putative allantoin permease Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Transport of allantoin%3B Belongs to the purine-cytosine permease (2. A. 39) family gene gene2611 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02612 S100027_02613 S100027_02613 S100027_02613 2496205 2496861 + Ribosomal-protein-serine acetyltransferase Acyltransferase%3B Cytoplasm%3B Transferase%3B This enzyme acetylates the N-terminal serine of ribosomal protein L7/L12. Belongs to the acetyltransferase family. RimL subfamily%3B Contains 1 N-acetyltransferase domain%3B KEGG: bce:BC2017 null%3B Transferring groups other than amino-acyl groups gene gene2612 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02613 S100027_02614 S100027_02614 S100027_02614 2496698 2497069 - uncharacterized protein gene gene2613 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02614 S100027_02615 S100027_02615 S100027_02615 2497134 2497586 - Protein ElaA Belongs to the UPF0039 (ElaA) family%3B Contains 1 N-acetyltransferase domain gene gene2614 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02615 S100027_02616 S100027_02616 S100027_02616 2497608 2498771 - uncharacterized protein To M. jannaschii MJ0043 N-terminal region gene gene2615 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02616 S100027_02617 S100027_02617 S100027_02617 2498768 2499334 - ADP-ribose diphosphatase Hydrolase%3B Magnesium%3B Metal-binding%3B Acts on ADP-mannose and ADP-glucose as well as ADP- ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process (By similarity)%3B Belongs to the Nudix hydrolase family. NudF subfamily%3B Contains 1 nudix hydrolase domain%3B KEGG: bli:BL05253 ADP-ribose pyrophosphatase gene gene2616 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02617 S100027_02618 S100027_02618 S100027_02618 2499402 2499578 + hypothetical protein gene gene2617 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02618 S100027_02619 S100027_02619 S100027_02619 2499629 2500234 + putative HTH-type transcriptional regulator YdgC DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH tetR-type DNA-binding domain gene gene2618 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02619 S100027_02620 S100027_02620 S100027_02620 2500240 2500587 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2619 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02620 S100027_02621 S100027_02621 S100027_02621 2500661 2501581 + putative oxidoreductase YqkF NADP%3B Oxidoreductase%3B Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily gene gene2620 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02621 S100027_02622 S100027_02622 S100027_02622 2501624 2501857 - uncharacterized protein gene gene2621 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02622 S100027_02623 S100027_02623 S100027_02623 2502014 2502943 + uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2622 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02623 S100027_02624 S100027_02624 S100027_02624 2502967 2503206 - uncharacterized protein gene gene2623 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02624 S100027_02625 S100027_02625 S100027_02625 2503220 2503543 - uncharacterized protein gene gene2624 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02625 S100027_02626 S100027_02626 S100027_02626 2503652 2503849 + hypothetical protein gene gene2625 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02626 S100027_02627 S100027_02627 S100027_02627 2503865 2504836 - UPF0157 protein YqkA Acyltransferase%3B Transferase%3B In the C-terminal sectio%3B belongs to the UPF0157 (GrpB) family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK3057 null%3B Transferring groups other than amino-acyl groups gene gene2626 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02627 S100027_02628 S100027_02628 S100027_02628 2504833 2505201 - Glutathione transferase Contains 1 ABM domain%3B KEGG: thi:THI_2919 glutathione S-transferase gene gene2627 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02628 S100027_02629 S100027_02629 S100027_02629 2505769 2506383 + Triacylglycerol lipase Hydrolase%3B Lipid degradation%3B Lipid metabolism%3B Secreted%3B Signal%3B Active toward p-nitrophenyl esters and triacylglycerides with a marked preference for esters with C8 acyl groups%3B Belongs to the AB hydrolase superfamily%3B KEGG: bli:BL05255 triacylglycerol lipase gene gene2628 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02629 S100027_02630 S100027_02630 S100027_02630 2506529 2506741 - hypothetical protein gene gene2629 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02630 S100027_02631 S100027_02631 S100027_02631 2507011 2508540 + Periplasmic dipeptide transport protein Chemotaxis%3B Disulfide bond%3B Peptide transport%3B Periplasm%3B Protein transport%3B Signal%3B Transport%3B Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis. Belongs to the bacterial solute-binding protein 5 family gene gene2630 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02631 S100027_02632 S100027_02632 S100027_02632 2508537 2509478 + Putative oligopeptide transport system permease protein oppB2 Cell membrane%3B Membrane%3B Peptide transport%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of a transport system that may be involved in oligopeptide uptake. Probably responsible for the translocation of the substrate across the membrane. Important for S. aureus growth and survival during the infection process (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2631 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02632 S100027_02633 S100027_02633 S100027_02633 2509475 2510296 + Dipeptide transport system permease protein DppC Cell membrane%3B Membrane%3B Peptide transport%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system for dipeptide%3B probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2632 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02633 S100027_02634 S100027_02634 S100027_02634 2510298 2511140 + Oligopeptide transport ATP-binding protein OppD ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Peptide transport%3B Protein transport%3B Transport%3B Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene2633 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02634 S100027_02635 S100027_02635 S100027_02635 2511140 2512939 + putative iron transport system ATP-binding protein ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of an ATP-driven transport system HI_0359/HI_0360/HI_0361/HI_0362 for iron. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene2634 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02635 S100027_02636 S100027_02636 S100027_02636 2512962 2513603 - hypothetical protein gene gene2635 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02636 S100027_02637 S100027_02637 S100027_02637 2513697 2513786 - hypothetical protein gene gene2636 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02637 S100027_02638 S100027_02638 S100027_02638 2513814 2514152 - SPBc2 prophage-derived uncharacterized protein YolD gene gene2637 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02638 S100027_02639 S100027_02639 S100027_02639 2514168 2515430 - Putative UV-damage repair protein UvrX DNA damage%3B DNA repair%3B DNA-binding%3B Magnesium%3B Metal-binding%3B Nucleotidyltransferase%3B Transferase%3B Belongs to the DNA polymerase type-Y family%3B Contains 1 umuC domain gene gene2638 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02639 S100027_02640 S100027_02640 S100027_02640 2515702 2515914 + uncharacterized protein gene gene2639 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02640 S100027_02641 S100027_02641 S100027_02641 2516042 2517280 + putative MFS-type transporter YqjV Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily. TCR/Tet family gene gene2640 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02641 S100027_02642 S100027_02642 S100027_02642 2517331 2517714 - Phosphoglycerate mutase (2%2C3-diphosphoglycerate-independent) KEGG: mlu:Mlut_09490 probable phosphoglycerate mutase gene gene2641 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02642 S100027_02643 S100027_02643 coaA coaA 2517729 2518688 - Pantothenate kinase ATP-binding%3B Coenzyme A biosynthesis%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the prokaryotic pantothenate kinase family%3B KEGG: psy:PCNPT3_12895 type I pantothenate kinase gene gene2642 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02643 S100027_02644 S100027_02644 S100027_02644 2518949 2519914 - hypothetical protein gene gene2643 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02644 S100027_02645 S100027_02645 S100027_02645 2519892 2520554 - Iron-chelate-transporting ATPase ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of a binding-protein-dependent transport system for arginine. Probably responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: aap:NT05HA_1149 iron complex transport system ATP-binding protein gene gene2644 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02645 S100027_02646 S100027_02646 S100027_02646 2520670 2521158 - hypothetical protein gene gene2645 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02646 S100027_02647 S100027_02647 S100027_02647 2521580 2521840 + hypothetical protein gene gene2646 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02647 S100027_02648 S100027_02648 S100027_02648 2522146 2522652 - hypothetical protein gene gene2647 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02648 S100027_02649 S100027_02649 S100027_02649 2522706 2523428 - UPF0714 protein YmaC Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0714 family gene gene2648 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02649 S100027_02650 S100027_02650 S100027_02650 2523859 2524641 - Hydroxysteroid 11-beta-dehydrogenase 1-like protein NADP%3B Oxidoreductase%3B Secreted%3B Signal%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family gene gene2649 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02650 S100027_02651 S100027_02651 S100027_02651 2524651 2525604 - Hydroxyacylglutathione hydrolase Hydrolase%3B Metal-binding%3B Zinc%3B Belongs to the metallo-beta-lactamase superfamily%3B KEGG: nph:NP_3944A hydroxyacylglutathione hydrolase gene gene2650 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02651 S100027_02652 S100027_02652 S100027_02652 2525994 2526815 + Pyrroline-5-carboxylate reductase Amino-acid biosynthesis%3B Cytoplasm%3B NADP%3B Oxidoreductase%3B Proline biosynthesis%3B Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline%3B Belongs to the pyrroline-5-carboxylate reductase family%3B KEGG: bsu:BSU23800 pyrroline-5-carboxylate reductase gene gene2651 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02652 S100027_02653 S100027_02653 S100027_02653 2526874 2528478 - uncharacterized protein To B. subtilis RocB gene gene2652 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02653 S100027_02654 S100027_02654 S100027_02654 2528605 2529684 + NADPH dehydrogenase Detoxification%3B Flavoprotein%3B FMN%3B NADP%3B Oxidoreductase%3B Catalyzes the reduction of the double bond of an array of alpha%2Cbeta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes%3B Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily%3B KEGG: bli:BL00797 NADPH2 dehydrogenase gene gene2653 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02654 S100027_02655 S100027_02655 S100027_02655 2529805 2531235 + hypothetical protein gene gene2654 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02655 S100027_02656 S100027_02656 S100027_02656 2531346 2532107 + uncharacterized protein gene gene2655 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02656 S100027_02657 S100027_02657 S100027_02657 2532141 2532290 - 50S ribosomal protein L33 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L33P family gene gene2656 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02657 S100027_02658 S100027_02658 S100027_02658 2532410 2533333 - Ribonuclease Z Endonuclease%3B Hydrolase%3B Metal-binding%3B Nuclease%3B tRNA processing%3B Zinc%3B Zinc phosphodiesterase%2C which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation%2C by removing a 3'-trailer from precursor tRNA%3B Belongs to the RNase Z family%3B KEGG: ebi:EbC_43140 ribonuclease Z gene gene2657 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02658 S100027_02659 S100027_02659 g6pD g6pD 2533552 2535030 + Glucose-6-phosphate dehydrogenase (NADP(+)) Carbohydrate metabolism%3B Glucose metabolism%3B NADP%3B Oxidoreductase%3B Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone%3B Belongs to the glucose-6-phosphate dehydrogenase family%3B KEGG: bli:BL01964 glucose-6-phosphate 1-dehydrogenase gene gene2658 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02659 S100027_02660 S100027_02660 S100027_02660 2535066 2537030 - Putative TRAP transporter large permease protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the TRAP transporter large permease family gene gene2659 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02660 S100027_02661 S100027_02661 S100027_02661 2537023 2537541 - hypothetical protein gene gene2660 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02661 S100027_02662 S100027_02662 S100027_02662 2537643 2538632 - 31 kDa immunogenic protein Signal. gene gene2661 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02662 S100027_02663 S100027_02663 S100027_02663 2538879 2539592 - Arabinose metabolism transcriptional repressor Cytoplasm%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcriptional repressor of the arabinose utilization genes%3B Contains 1 HTH gntR-type DNA-binding domain gene gene2662 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02663 S100027_02664 S100027_02664 S100027_02664 2539712 2541127 - 6-phospho-beta-glucosidase Disulfide bond%3B Glycoprotein%3B Glycosidase%3B Hydrolase%3B Signal%3B Belongs to the glycosyl hydrolase 1 family%3B KEGG: bli:BL00115 6-phospho-beta-glucosidase gene gene2663 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02664 S100027_02665 S100027_02665 S100027_02665 2541143 2542459 - Oligo-beta-mannoside permease IIC component Cell membrane%3B Membrane%3B Phosphotransferase system%3B Polysaccharide transport%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in the transport of oligo- glucomannans such as cellobiose or mannobiose (Probable)%3B Contains 1 PTS EIIC type-3 domain gene gene2664 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02665 S100027_02666 S100027_02666 S100027_02666 2542499 2542831 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cytoplasm%3B Kinase%3B Phosphotransferase system%3B Polysaccharide transport%3B Sugar transport%3B Transferase%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in the transport of oligo- glucomannans such as cellobiose or mannobiose (Probable)%3B Contains 1 PTS EIIA type-3 domain%3B KEGG: bli:BL05259 PTS system%2C cellobiose-specific IIA component gene gene2665 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02666 S100027_02667 S100027_02667 S100027_02667 2542837 2543145 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cytoplasm%3B Kinase%3B Phosphotransferase system%3B Polysaccharide transport%3B Sugar transport%3B Transferase%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in the transport of oligo- glucomannans such as cellobiose or mannobiose (Probable)%3B Contains 1 PTS EIIB type-3 domain%3B KEGG: eca:ECA3645 PTS system%2C cellobiose-specific IIB component gene gene2666 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02667 S100027_02668 S100027_02668 S100027_02668 2543295 2544956 - Alkaline phosphatase Hydrolase%3B Magnesium%3B Metal-binding%3B Phosphoprotein%3B Signal%3B Zinc%3B Belongs to the alkaline phosphatase family%3B KEGG: bli:BL01381 alkaline phosphatase gene gene2667 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02668 S100027_02669 S100027_02669 S100027_02669 2545096 2545881 - Glucose 1-dehydrogenase (NAD(P)(+)) NADP%3B Oxidoreductase%3B Stress response%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bli:BL01382 glucose 1-dehydrogenase gene gene2668 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02669 S100027_02670 S100027_02670 gntZ gntZ 2545999 2547408 - Phosphogluconate dehydrogenase (NADP(+)-dependent%2C decarboxylating) Gluconate utilization%3B NADP%3B Oxidoreductase%3B Pentose shunt%3B Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2)%2C with concomitant reduction of NADP to NADPH%3B Belongs to the 6-phosphogluconate dehydrogenase family%3B KEGG: eco:b2029 6-phosphogluconate dehydrogenase gene gene2669 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02670 S100027_02671 S100027_02671 dpo4 dpo4 2547495 2548751 - DNA-directed DNA polymerase Cytoplasm%3B DNA damage%3B DNA repair%3B DNA replication%3B DNA-binding%3B DNA-directed DNA polymerase%3B Magnesium%3B Metal-binding%3B Mutator protein%3B Nucleotidyltransferase%3B Transferase%3B Poorly processive%2C error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks%2C which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis%2C in conjunction with the beta clamp from PolIII (By similarity)%3B Belongs to the DNA polymerase type-Y family%3B Contains 1 umuC domain%3B KEGG: bli:BL01384 DNA polymerase IV gene gene2670 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02671 S100027_02672 S100027_02672 S100027_02672 2548832 2549119 + Membrane protein insertion and folding monitor Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Sensor protein that upregulates translation of the secondary membrane protein insertase (MisCB/YqjG) when activity of the primary membrane protein insertase (MisCA/SpoIIIJ) is limited. Acts as a ribosome-nascent chain complex. When the primary membrane protein insertase activity or level is reduced%2C the membrane insertion of MifM is impaired%2C which induces arrest of MifM translation and unfolding of the mRNA hairpin. Unfolding leads to translation of the downstream gene%2C which encodes the secondary membrane protein insertase MisCB/YqjG. Translation arrest of MifM is mediated by interaction of its C-terminal domain with the ribosomal polypeptide exit tunnel. Undergoes multisite stalling%2C which may allow a sufficient duration of ribosomal stalling and consequently sufficient levels of MisCB/YqjG gene gene2671 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02672 S100027_02673 S100027_02673 S100027_02673 2549168 2549992 + Membrane protein insertase MisCB Cell membrane%3B Chaperone%3B Lipoprotein%3B Membrane%3B Palmitate%3B Protein transport%3B Signal%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex%2C as well as at least some lipoproteins (By similarity). Also involved in protein secretion processes. It has an overlapping%2C although partly distinct%2C function compared to SpoIIIJ(MisCB)%3B Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily gene gene2672 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02673 S100027_02674 S100027_02674 S100027_02674 2550153 2551271 - Propionyl-CoA carboxylase Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Zinc%3B Could be a peptidase. Belongs to the peptidase M20A family%3B KEGG: bya:BANAU_2374 propionyl-CoA carboxylase beta chain gene gene2673 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02674 S100027_02675 S100027_02675 S100027_02675 2551292 2552821 - Propionyl-CoA carboxylase ATP-binding%3B Ligase%3B Nucleotide-binding%3B Belongs to the AccD/PCCB family%3B Contains 1 carboxyltransferase domain%3B KEGG: bli:BL01386 propionyl-CoA carboxylase beta chain gene gene2674 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02675 S100027_02676 S100027_02676 S100027_02676 2553156 2554127 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2675 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02676 S100027_02677 S100027_02677 S100027_02677 2554188 2554916 - Polar-amino-acid-transporting ATPase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3. A. 1. 11. 1) family%3B Contains 1 ABC transporter domain%3B KEGG: sty:STY1436 polar amino acid transport system ATP-binding protein gene gene2676 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02677 S100027_02678 S100027_02678 S100027_02678 2554903 2555565 - Arginine transport system permease protein ArtQ Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of a binding-protein-dependent transport system for arginine. Probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2677 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02678 S100027_02679 S100027_02679 S100027_02679 2555654 2556421 - putative amino-acid-binding protein YxeM Amino-acid transport%3B Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S- methylcysteine. Belongs to the bacterial solute-binding protein 3 family gene gene2678 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02679 S100027_02680 S100027_02680 S100027_02680 2556472 2556645 - hypothetical protein gene gene2679 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02680 S100027_02681 S100027_02681 S100027_02681 2556645 2557082 - UPF0403 protein Belongs to the UPF0403 family gene gene2680 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02681 S100027_02682 S100027_02682 S100027_02682 2557264 2558166 + Diacylglycerol kinase (ATP) ATP-binding%3B Kinase%3B Lipid biosynthesis%3B Lipid metabolism%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG). In fact%2C is not able to exhibit diacylglycerol kinase activity in vitro. Belongs to the diacylglycerol/lipid kinase family%3B Contains 1 DAGKc domain%3B KEGG: ssd:SPSINT_1652 diacylglycerol kinase (ATP) gene gene2681 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02682 S100027_02683 S100027_02683 bkdB bkdB 2558187 2559467 - Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase Acyltransferase%3B Glycolysis%3B Lipoyl%3B Transferase%3B The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1)%2C lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: bsu:BSU24030 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) gene gene2682 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02683 S100027_02684 S100027_02684 S100027_02684 2559491 2560474 - 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) Oxidoreductase%3B Thiamine pyrophosphate%3B KEGG: sur:STAUR_4870 2-oxoisovalerate dehydrogenase E1 component beta subunit gene gene2683 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02684 S100027_02685 S100027_02685 S100027_02685 2560487 2561479 - 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) Magnesium%3B Metal-binding%3B Oxidoreductase%3B Thiamine pyrophosphate%3B The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1)%2C lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the BCKDHA family%3B KEGG: bli:BL01504 2-oxoisovalerate dehydrogenase E1 component alpha subunit gene gene2684 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02685 S100027_02686 S100027_02686 S100027_02686 2561502 2562923 - Glutathione-disulfide reductase Cytoplasm%3B Disulfide bond%3B FAD%3B Flavoprotein%3B Glycolysis%3B NAD%3B Oxidoreductase%3B Redox-active center%3B The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of 3 enzymatic components: branched-chain alpha-keto acid decarboxylase (E1)%2C lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: abo:ABO_1423 glutathione reductase (NADPH) gene gene2685 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02686 S100027_02687 S100027_02687 S100027_02687 2562913 2564019 - Butyrate kinase ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the acetokinase family%3B KEGG: bli:BL01502 butyrate kinase gene gene2686 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02687 S100027_02688 S100027_02688 S100027_02688 2564058 2565152 - Leucine dehydrogenase Branched-chain amino acid catabolism%3B NAD%3B Oxidoreductase%3B Catalyzes the reversible deamination of L-leucine to 4- methyl-2-oxopentanoate. Can also use other substrates such as L- isoleucine%2C L-valine and L-2-aminobutyrate. The 2-oxo analogs of branched-chain and straight-chain amino acids serve as good substrates for the reverse reaction%3B Belongs to the Glu/Leu/Phe/Val dehydrogenases family%3B KEGG: bsu:BSU24080 leucine dehydrogenase gene gene2687 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02688 S100027_02689 S100027_02689 S100027_02689 2565156 2566067 - Phosphate butyryltransferase Acyltransferase%3B Transferase%3B Catalyzes the conversion of butyryl-CoA through butyryl phosphate to butyrate. Belongs to the phosphate acetyltransferase and butyryltransferase family%3B KEGG: bli:BL01500 phosphate butyryltransferase gene gene2688 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02689 S100027_02690 S100027_02690 dctS dctS 2566194 2568263 - Histidine kinase ATP-binding%3B Cell membrane%3B DNA-binding%3B Membrane%3B Nucleotide-binding%3B Repeat%3B Transcription%3B Transcription regulation%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Contains 1 PAC (PAS-associated C-terminal) domain%3B Contains 2 PAS (PER-ARNT-SIM) domains%3B Contains 1 sigma-54 factor interaction domain%3B KEGG: amt:Amet_2967 two-component system%2C CitB family%2C sensor histidine kinase DctS gene gene2689 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02690 S100027_02691 S100027_02691 S100027_02691 2568414 2568668 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2690 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02691 S100027_02692 S100027_02692 S100027_02692 2568719 2569444 - Glycerophosphodiester phosphodiesterase Contains 1 GP-PDE domain%3B KEGG: pgb:H744_1c0275 glycerophosphoryl diester phosphodiesterase gene gene2691 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02692 S100027_02693 S100027_02693 S100027_02693 2569578 2570198 - N-acetylmuramoyl-L-alanine amidase Hydrolase%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B KEGG: bli:BL01514 N-acetylmuramoyl-L-alanine amidase gene gene2692 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02693 S100027_02694 S100027_02694 S100027_02694 2570234 2570554 - Membrane-bound protein LytA Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal. gene gene2693 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02694 S100027_02695 S100027_02695 S100027_02695 2571094 2571423 - Serine O-acetyltransferase Acyltransferase%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Magnesium%3B Metal-binding%3B Multifunctional enzyme%3B Nucleotidyltransferase%3B Peptidoglycan synthesis%3B Repeat%3B Transferase%3B Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P)%2C which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate)%2C a reaction catalyzed by the N-terminal domain%3B In the N-terminal sectio%3B belongs to the N- acetylglucosamine-1-phosphate uridyltransferase family%3B In the C-terminal sectio%3B belongs to the transferase hexapeptide repeat family%3B KEGG: blh:BaLi_c26760 serine O-acetyltransferase gene gene2694 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02695 S100027_02696 S100027_02696 S100027_02696 2571553 2571849 - hypothetical protein gene gene2695 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02696 S100027_02697 S100027_02697 S100027_02697 2572222 2573022 - Stage 0 sporulation protein Activator%3B Calcium%3B Cytoplasm%3B DNA-binding%3B Metal-binding%3B Phosphoprotein%3B Repressor%3B Sporulation%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB%2C activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box) (By similarity)%3B Contains 1 response regulatory domain gene gene2696 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02697 S100027_02698 S100027_02698 S100027_02698 2573312 2574652 - SpoIVB peptidase Hydrolase%3B Protease%3B Serine protease%3B Signal%3B Sporulation%3B Zymogen%3B Plays a central role in the sigma-K checkpoint which coordinates gene expression during the later stages of spore formation. The protease is activated by trans cleavage of the zymogen precursor producing SpoIVB-45 kDa. This undergoes further trimming by cis cleavage to form SpoIVB-43 kDa and SpoIVB-42 kDa. The protease then cleaves the C-terminus of the SpoIVFA metalloprotease activating the latter%3B Contains 1 PDZ (DHR) domain%3B Contains 1 peptidase S55 domain%3B KEGG: bli:BL01519 stage IV sporulation protein B gene gene2697 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02698 S100027_02699 S100027_02699 S100027_02699 2574778 2576508 - DNA repair protein RecN ATP-binding%3B Cytoplasm%3B DNA damage%3B DNA repair%3B Nucleotide-binding%3B Involved in recombinational repair of damaged DNA. Seems to be the first protein recruited to repair centers%2C foci that are the site of double-strand DNA break(s)%2C followed by RecO and then RecF. Belongs to the RecN family gene gene2698 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02699 S100027_02700 S100027_02700 S100027_02700 2576540 2576989 - Arginine repressor Amino-acid biosynthesis%3B Arginine biosynthesis%3B Cytoplasm%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Regulates arginine biosynthesis genes%3B Belongs to the ArgR family gene gene2699 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02700 S100027_02701 S100027_02701 tlyA tlyA 2577155 2578000 - 23S rRNA (cytidine(1920)-2'-O)-methyltransferase Methyltransferase%3B RNA-binding%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B Belongs to the TlyA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: bli:BL01522 23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase gene gene2700 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02701 S100027_02702 S100027_02702 S100027_02702 2577997 2579865 - 1-deoxy-D-xylulose-5-phosphate synthase Isoprene biosynthesis%3B Magnesium%3B Metal-binding%3B Thiamine biosynthesis%3B Thiamine pyrophosphate%3B Transferase%3B Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)%3B Belongs to the transketolase family. DXPS subfamily%3B KEGG: serf:L085_13545 1-deoxy-D-xylulose-5-phosphate synthase gene gene2701 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02702 S100027_02703 S100027_02703 ggpS ggpS 2580132 2581022 - Dimethylallyltranstransferase Carotenoid biosynthesis%3B Chlorophyll biosynthesis%3B Cyanelle%3B Isoprene biosynthesis%3B Magnesium%3B Metal-binding%3B Photosynthesis%3B Plastid%3B Transferase%3B Catalyzes the condensation of farnesyl diphosphate (FPP) and isopentenyl diphosphate (IPP) to yield geranylgeranyl diphosphate (GGPP) needed for biosynthesis of carotenoids and diterpenes%3B Belongs to the FPP/GGPP synthase family%3B KEGG: bli:BL01524 geranylgeranyl diphosphate synthase%2C type II gene gene2702 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02703 S100027_02704 S100027_02704 xseB xseB 2581012 2581272 - Exodeoxyribonuclease VII Cytoplasm%3B Exonuclease%3B Hydrolase%3B Nuclease%3B Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides%2C which are then degraded further into small acid-soluble oligonucleotides%3B Belongs to the XseB family%3B KEGG: bli:BL01525 exodeoxyribonuclease VII small subunit%3B overlaps another CDS with the same product name gene gene2703 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02704 S100027_02705 S100027_02705 xseA xseA 2581265 2582614 - Exodeoxyribonuclease VII Cytoplasm%3B Exonuclease%3B Hydrolase%3B Nuclease%3B Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides%2C which are then degraded further into small acid-soluble oligonucleotides%3B Belongs to the XseA family%3B KEGG: bli:BL01526 exodeoxyribonuclease VII large subunit%3B overlaps another CDS with the same product name gene gene2704 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02705 S100027_02706 S100027_02706 folD folD 2582691 2583545 - Methylenetetrahydrofolate dehydrogenase (NADP(+)) Amino-acid biosynthesis%3B Histidine biosynthesis%3B Hydrolase%3B Methionine biosynthesis%3B Multifunctional enzyme%3B NADP%3B One-carbon metabolism%3B Oxidoreductase%3B Purine biosynthesis%3B Catalyzes the oxidation of 5%2C10- methylenetetrahydrofolate to 5%2C10-methenyltetrahydrofolate and then the hydrolysis of 5%2C10-methenyltetrahydrofolate to 10- formyltetrahydrofolate%3B Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family%3B KEGG: bma:BMA1724 methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase gene gene2705 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02706 S100027_02707 S100027_02707 S100027_02707 2583562 2583951 - N utilization substance protein B like protein Transcription%3B Transcription regulation%3B Transcription termination%3B Involved in the transcription termination process%3B Belongs to the NusB family gene gene2706 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02707 S100027_02708 S100027_02708 S100027_02708 2584244 2584654 - uncharacterized protein Belongs to the asp23 family gene gene2707 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02708 S100027_02709 S100027_02709 S100027_02709 2584675 2586027 - Acetyl-CoA carboxylase ATP-binding%3B Biotin%3B Ligase%3B Magnesium%3B Nucleotide-binding%3B Contains 1 ATP-grasp domain%3B Contains 1 biotin carboxylation domain%3B KEGG: wgl:WIGMOR_0138 acetyl-CoA carboxylase%2C biotin carboxylase subunit gene gene2708 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02709 S100027_02710 S100027_02710 S100027_02710 2586039 2586518 - Biotin carboxyl carrier protein of acetyl-CoA carboxylase Biotin%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B This protein is a component of the acetyl coenzyme A carboxylase comple%3B first%2C biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. Contains 1 biotinyl-binding domain gene gene2709 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02710 S100027_02711 S100027_02711 S100027_02711 2586692 2587330 - Stage III sporulation protein AH Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Involved in forespore engulfment. Forms a channel with SpoIIIAH that is open on the forespore end and closed (or gated) on the mother cell end. This allows sigma-E-directed gene expression in the mother-cell compartment of the sporangium to trigger the activation of sigma-G forespore-specific gene expression by a pathway of intercellular signaling gene gene2710 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02711 S100027_02712 S100027_02712 S100027_02712 2587331 2588026 - Stage III sporulation protein AG Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix. gene gene2711 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02712 S100027_02713 S100027_02713 S100027_02713 2588019 2588648 - Stage III sporulation protein AF Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix. gene gene2712 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02713 S100027_02714 S100027_02714 S100027_02714 2588660 2589865 - Stage III sporulation protein AE Cell membrane%3B Membrane%3B Signal%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Required during sporulation for activation of sigma factor SpoIIIG/SigG after engulfment is completed in the prespore. Overexpression in the absence of SpoIIIJ is synthetically lethal gene gene2713 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02714 S100027_02715 S100027_02715 S100027_02715 2589887 2590252 - Stage III sporulation protein AD Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix. gene gene2714 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02715 S100027_02716 S100027_02716 S100027_02716 2590295 2590501 - Stage III sporulation protein AC Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix. gene gene2715 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02716 S100027_02717 S100027_02717 S100027_02717 2590524 2591039 - Stage III sporulation protein Sporulation. gene gene2716 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02717 S100027_02718 S100027_02718 S100027_02718 2591033 2591956 - Stage III sporulation protein AA ATP-binding%3B Nucleotide-binding%3B Sporulation. gene gene2717 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02718 S100027_02719 S100027_02719 S100027_02719 2592048 2592329 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2718 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02719 S100027_02720 S100027_02720 S100027_02720 2592492 2593049 - Elongation factor P Cytoplasm%3B Elongation factor%3B Protein biosynthesis%3B Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA%2C thus increasing their reactivity as acceptors for peptidyl transferase%3B Belongs to the elongation factor P family gene gene2719 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02720 S100027_02721 S100027_02721 pepP pepP 2593081 2594142 - Xaa-Pro aminopeptidase Hydrolase%3B Manganese%3B Metal-binding%3B Belongs to the peptidase M24B family%3B KEGG: bsu:BSU24460 Xaa-Pro aminopeptidase gene gene2720 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02721 S100027_02722 S100027_02722 aroQ aroQ 2594158 2594595 - 3-dehydroquinate dehydratase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Lyase%3B Catalyzes a trans-dehydration via an enolate intermediate%3B Belongs to the type-II 3-dehydroquinase family%3B KEGG: buh:BUAMB_375 3-dehydroquinate dehydratase II gene gene2721 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02722 S100027_02723 S100027_02723 S100027_02723 2594675 2595211 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2722 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02723 S100027_02724 S100027_02724 S100027_02724 2595463 2596416 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2723 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02724 S100027_02725 S100027_02725 S100027_02725 2596455 2596841 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2724 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02725 S100027_02726 S100027_02726 S100027_02726 2596838 2597713 - uncharacterized protein Cell membrane%3B Hydrolase%3B Lipid degradation%3B Lipid metabolism%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Probable lipid hydrolase%3B Contains 1 patatin domain gene gene2725 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02726 S100027_02727 S100027_02727 S100027_02727 2598047 2598475 - Transcriptional regulator MntR Activator%3B Cytoplasm%3B DNA-binding%3B Manganese%3B Transcription%3B Transcription regulation%3B Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon%3B Contains 1 HTH dtxR-type DNA-binding domain gene gene2726 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02727 S100027_02728 S100027_02728 S100027_02728 2598567 2599403 - Lipoate--protein ligase Acyltransferase%3B Transferase%3B Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH%2C an intermediate carrier during protein lipoylation%3B Belongs to the octanoyltransferase LipM family%3B Contains 1 BPL/LPL catalytic domain%3B KEGG: bsu:BSU24530 lipoate-protein ligase A gene gene2727 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02728 S100027_02729 S100027_02729 glpE glpE 2599590 2599976 + Thiosulfate sulfurtransferase Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Contains 1 rhodanese domain%3B KEGG: pao:Pat9b_3716 thiosulfate sulfurtransferase gene gene2728 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02729 S100027_02730 S100027_02730 S100027_02730 2600142 2601026 - Glycine betaine-binding protein OpuAC Amino-acid transport%3B Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B Involved in a multicomponent binding-protein-dependent transport system for glycine betaine gene gene2729 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02730 S100027_02731 S100027_02731 S100027_02731 2601026 2601880 - Glycine betaine transport system permease protein OpuAB Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in a multicomponent binding-protein-dependent transport system for glycine betain%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2730 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02731 S100027_02732 S100027_02732 proV proV 2601880 2603127 - Quaternary-amine-transporting ATPase Amino-acid transport%3B ATP-binding%3B CBS domain%3B Hydrolase%3B Nucleotide-binding%3B Repeat%3B Transport%3B Involved in a multicomponent binding-protein-dependent transport system for glycine betaine. Probably responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B Contains 2 CBS domains%3B KEGG: bli:BL01559 glycine betaine/proline transport system ATP-binding protein gene gene2731 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02732 S100027_02733 S100027_02733 S100027_02733 2603491 2604948 - Glycine dehydrogenase (aminomethyl-transferring) Oxidoreductase%3B Pyridoxal phosphate%3B The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofacto%3B CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein%3B Belongs to the GcvP family. C-terminal subunit subfamily%3B KEGG: bli:BL01560 glycine dehydrogenase subunit 2%3B overlaps another CDS with the same product name gene gene2732 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02733 S100027_02734 S100027_02734 S100027_02734 2604941 2606287 - Glycine dehydrogenase (aminomethyl-transferring) Oxidoreductase%3B The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofacto%3B CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein%3B Belongs to the GcvP family. N-terminal subunit subfamily%3B KEGG: bsu:BSU24560 glycine dehydrogenase subunit 1%3B overlaps another CDS with the same product name gene gene2733 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02734 S100027_02735 S100027_02735 gcvT gcvT 2606318 2607412 - Aminomethyltransferase Aminotransferase%3B Transferase%3B The glycine cleavage system catalyzes the degradation of glycine%3B Belongs to the GcvT family%3B KEGG: tig:THII_2082 aminomethyltransferase gene gene2734 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02735 S100027_02736 S100027_02736 hepA hepA 2608005 2609684 + putative ATP-dependent helicase YqhH ATP-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Belongs to the SNF2/RAD54 helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: eco:b0059 ATP-dependent helicase HepA%3B Acting on ATP%3B involved in cellular and subcellular movement gene gene2735 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02736 S100027_02737 S100027_02737 S100027_02737 2609691 2610485 + uncharacterized protein gene gene2736 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02737 S100027_02738 S100027_02738 S100027_02738 2610676 2610852 + Protein SinI Acts as an antagonist to SinR. SinI prevents SinR from binding to its target sequence on the gene for AprE (By similarity)%3B Contains 1 Sin domain gene gene2737 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02738 S100027_02739 S100027_02739 S100027_02739 2610880 2611221 + HTH-type transcriptional regulator SinR Activator%3B Bacterial flagellum biogenesis%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Affects autolysin level and flagellation. Contains 1 HTH cro/C1-type DNA-binding domain%3B Contains 1 Sin domain gene gene2738 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02739 S100027_02740 S100027_02740 S100027_02740 2611326 2612120 - Spore coat-associated protein Secreted%3B Signal%3B Sporulation%3B Belongs to the peptidase M73 family gene gene2739 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02740 S100027_02741 S100027_02741 sipW sipW 2612194 2612778 - Signal peptidase I Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Belongs to the peptidase S26B family%3B KEGG: bli:BL01564 signal peptidase%2C endoplasmic reticulum-type%3B Acting on peptide bonds (peptidases) gene gene2740 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02741 S100027_02742 S100027_02742 S100027_02742 2612775 2613503 - uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2741 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02742 S100027_02743 S100027_02743 S100027_02743 2613780 2614100 + uncharacterized protein Signal. gene gene2742 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02743 S100027_02744 S100027_02744 S100027_02744 2614124 2614306 - uncharacterized protein gene gene2743 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02744 S100027_02745 S100027_02745 S100027_02745 2614395 2614760 - ComG operon protein Cell membrane%3B Competence%3B Disulfide bond%3B Membrane%3B Peptidoglycan-anchor%3B Secreted%3B Signal%3B Transport%3B Required for transformation and DNA binding gene gene2744 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02745 S100027_02746 S100027_02746 S100027_02746 2614773 2615261 - ComG operon protein Cell membrane%3B Competence%3B Membrane%3B Required for transformation and DNA binding gene gene2745 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02746 S100027_02747 S100027_02747 S100027_02747 2615501 2615947 - ComG operon protein Cell membrane%3B Competence%3B Membrane%3B Methylation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Required for transformation and DNA binding gene gene2746 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02747 S100027_02748 S100027_02748 S100027_02748 2615944 2616237 - ComG operon protein 3 like protein Cell membrane%3B Competence%3B Disulfide bond%3B Membrane%3B Methylation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Required for transformation and DNA binding%3B Belongs to the ComGC family gene gene2747 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02748 S100027_02749 S100027_02749 S100027_02749 2616251 2617285 - ComG operon protein Cell membrane%3B Competence%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Required for transformation and DNA binding%3B Belongs to the GSP F family%3B overlaps another CDS with the same product name gene gene2748 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02749 S100027_02750 S100027_02750 S100027_02750 2617275 2618339 - ComG operon protein ATP-binding%3B Cell membrane%3B Competence%3B Membrane%3B Nucleotide-binding%3B Transport%3B Required for uptake of DNA by competent cells%3B Belongs to the GSP E family%3B overlaps another CDS with the same product name gene gene2749 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02750 S100027_02751 S100027_02751 S100027_02751 2618496 2619335 - RsbT co-antagonist protein RsbRB Phosphoprotein%3B One of 4 functionally non-identical RsbR paralogs%2C it functions in the environmental signaling branch of the general stress response. Negative regulator of sigma-B activity. Non- phosphorylated RsbS binds to RsbT%2C preventing its association with RsbU. Requires any one of RsbRA%2C RsbRB%2C RsbRC or RsbRD to sequester RsbT. When RsbS and the RsbR paralog(s) are phosphorylated%2C they release RsbT%2C which can then bind and activate RsbU. Contains 1 STAS domain gene gene2750 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02751 S100027_02752 S100027_02752 S100027_02752 2619443 2619514 + tRNA-Gln tRNA gene2751 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02752 S100027_02753 S100027_02753 S100027_02753 2619577 2619954 - Arsenate reductase (glutaredoxin) Activator%3B Cytoplasm%3B Repressor%3B Stress response%3B Transcription%3B Transcription regulation%3B Regulates transcription of a subregulon within the general stress response. Exerts positive and negative effects in response to ethanol stress%3B Belongs to the ArsC family%3B KEGG: bli:BL01574 arsenate reductase gene gene2752 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02753 S100027_02754 S100027_02754 S100027_02754 2620163 2620408 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2753 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02754 S100027_02755 S100027_02755 S100027_02755 2620446 2621084 - Hydroxyacylglutathione hydrolase Hydrolase%3B Metal-binding%3B Zinc%3B Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family%3B KEGG: rha:RHA1_ro06903 hydroxyacylglutathione hydrolase gene gene2754 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02755 S100027_02756 S100027_02756 S100027_02756 2621240 2621413 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2755 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02756 S100027_02757 S100027_02757 S100027_02757 2621474 2621788 - UPF0045 protein YqgV Belongs to the UPF0045 family gene gene2756 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02757 S100027_02758 S100027_02758 S100027_02758 2621804 2622913 - putative lipoprotein YqgU Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal. gene gene2757 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02758 S100027_02759 S100027_02759 yqgT yqgT 2622968 2624092 - Gamma-D-glutamyl-meso-diaminopimelate peptidase Hydrolase%3B Metalloprotease%3B Protease%3B Zinc%3B Belongs to the peptidase M14 family%3B KEGG: bli:BL01578 g-D-glutamyl-meso-diaminopimelate peptidase gene gene2758 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02759 S100027_02760 S100027_02760 S100027_02760 2624234 2625181 - Iron(3+)-hydroxamate-binding protein FhuD Cell membrane%3B Ion transport%3B Iron%3B Iron transport%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B Part of the ABC transporter complex FhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Required for the transport of ferrichrome and coprogen%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene2759 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02760 S100027_02761 S100027_02761 S100027_02761 2625178 2625324 - hypothetical protein gene gene2760 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02761 S100027_02762 S100027_02762 S100027_02762 2625350 2627248 - Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase Cell membrane%3B Manganese%3B Membrane%3B Metal-binding%3B Secreted%3B Transmembrane%3B Transmembrane helix%3B Belongs to the LTA synthase family%3B KEGG: lrh:LGG_00830 lipoteichoic acid synthase gene gene2761 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02762 S100027_02763 S100027_02763 S100027_02763 2627430 2628404 - Glucokinase ATP-binding%3B Cytoplasm%3B Glycolysis%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the ROK (NagC/XylR) family%3B KEGG: bli:BL01581 glucokinase gene gene2762 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02763 S100027_02764 S100027_02764 S100027_02764 2628429 2628626 - uncharacterized protein gene gene2763 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02764 S100027_02765 S100027_02765 S100027_02765 2628728 2630182 - Stage V sporulation protein AF Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Belongs to the GerABKA family gene gene2764 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02765 S100027_02766 S100027_02766 gluP gluP 2630259 2631797 - Rhomboid protease Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Repeat%3B Serine protease%3B TPR repeat%3B Transmembrane%3B Transmembrane helix%3B Rhomboid-type serine protease that catalyzes intramembrane proteolysis. Important for normal cell division and sporulation. May act as a glucose exporter%3B Belongs to the peptidase S54 family%3B Contains 2 TPR repeats%3B KEGG: bli:BL03719 rhomboid protease GluP gene gene2765 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02766 S100027_02767 S100027_02767 S100027_02767 2631893 2632066 - uncharacterized protein gene gene2766 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02767 S100027_02768 S100027_02768 S100027_02768 2632116 2632643 - 5-formyltetrahydrofolate cyclo-ligase ATP-binding%3B Nucleotide-binding%3B Belongs to the 5-formyltetrahydrofolate cyclo-ligase family%3B KEGG: bli:BL03718 5-formyltetrahydrofolate cyclo-ligase gene gene2767 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02768 S100027_02769 S100027_02769 S100027_02769 2632738 2632887 - 50S ribosomal protein L33 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L33P family gene gene2768 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02769 S100027_02770 S100027_02770 S100027_02770 2632991 2634103 - Glycogen(starch) synthase Glycosyltransferase%3B Transferase%3B Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: dca:Desca_1720 glycogen(starch) synthase gene gene2769 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02770 S100027_02771 S100027_02771 S100027_02771 2634100 2634597 - uncharacterized protein gene gene2770 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02771 S100027_02772 S100027_02772 S100027_02772 2634758 2635123 + uncharacterized protein Cell membrane%3B Coiled coil%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B overlaps another CDS with the same product name gene gene2771 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02772 S100027_02773 S100027_02773 S100027_02773 2635120 2635599 + uncharacterized protein Signal%3B overlaps another CDS with the same product name gene gene2772 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02773 S100027_02774 S100027_02774 S100027_02774 2635691 2636470 - Phosphate-transporting ATPase ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Phosphate transport%3B Transport%3B Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphate importer (TC 3. A. 1. 7) family%3B Contains 1 ABC transporter domain%3B KEGG: bli:BL03715 phosphate transport system ATP-binding protein gene gene2773 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02774 S100027_02775 S100027_02775 S100027_02775 2636483 2637310 - Phosphate-transporting ATPase ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Phosphate transport%3B Transport%3B Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphate importer (TC 3. A. 1. 7) family%3B Contains 1 ABC transporter domain%3B KEGG: bli:BL03714 phosphate transport system ATP-binding protein gene gene2774 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02775 S100027_02776 S100027_02776 S100027_02776 2637330 2638217 - putative ABC transporter permease protein YqgI Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system YqgGHIJK. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2775 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02776 S100027_02777 S100027_02777 S100027_02777 2638217 2639146 - putative ABC transporter permease protein YqgH Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system YqgGHIJK. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2776 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02777 S100027_02778 S100027_02778 S100027_02778 2639220 2640137 - Phosphate-binding protein PstS Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Phosphate transport%3B Signal%3B Transport%3B Part of the ABC transporter complex PstSACB involved in phosphate import%3B Belongs to the PstS family gene gene2777 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02778 S100027_02779 S100027_02779 S100027_02779 2640330 2642450 - uncharacterized protein Cell membrane%3B Cell shape%3B Membrane%3B Peptidoglycan synthesis%3B Transmembrane%3B Transmembrane helix%3B Belongs to the transpeptidase family%3B KEGG: seq:SZO_13590 penicillin-binding protein 2B%3B Aminoacyltransferases gene gene2778 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02779 S100027_02780 S100027_02780 S100027_02780 2642552 2643838 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2779 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02780 S100027_02781 S100027_02781 S100027_02781 2644018 2644626 - Superoxide dismutase Iron%3B Manganese%3B Metal-binding%3B Oxidoreductase%3B Stress response%3B Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems%3B Belongs to the iron/manganese superoxide dismutase family%3B KEGG: bva:BVAF_021 superoxide dismutase%2C Fe-Mn family gene gene2780 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02781 S100027_02782 S100027_02782 S100027_02782 2644811 2645293 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2781 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02782 S100027_02783 S100027_02783 S100027_02783 2645451 2646209 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2782 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02783 S100027_02784 S100027_02784 S100027_02784 2646294 2646599 + uncharacterized protein Cell wall%3B Membrane%3B Secreted%3B Transmembrane%3B Transmembrane helix%3B Contains 1 LysM repeat gene gene2783 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02784 S100027_02785 S100027_02785 gcpE gcpE 2646712 2647824 + (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin) 4Fe-4S%3B Iron%3B Iron-sulfur%3B Isoprene biosynthesis%3B Metal-binding%3B Oxidoreductase%3B Converts 2C-methyl-D-erythritol 2%2C4-cyclodiphosphate (ME-2%2C4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate%3B Belongs to the IspG family%3B KEGG: bsu:BSU25070 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase gene gene2784 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02785 S100027_02786 S100027_02786 S100027_02786 2647864 2648235 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2785 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02786 S100027_02787 S100027_02787 S100027_02787 2648355 2648957 + Putative nucleotidase YqfW Hydrolase%3B Belongs to the 5'(3')-deoxyribonucleotidase family gene gene2786 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02787 S100027_02788 S100027_02788 S100027_02788 2649028 2649459 - Zinc-specific metallo-regulatory protein Cytoplasm%3B DNA-binding%3B Metal-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Zinc%3B Acts as a negative controlling element%2C employing Zn(2+) as a cofactor to bind the operator of the repressed genes. Required for the zinc-specific repression of two operons implicated in zinc uptake%2C yciC and ycdHIyceA. Also represses the expression of rpmE2%2C the gene for ribosomal protein L31B%2C which is expressed only after the end of exponential growth%3B Belongs to the Fur family gene gene2787 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02788 S100027_02789 S100027_02789 S100027_02789 2649437 2650297 - 29 kDa membrane protein in psaA 5'region Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the ABC-3 integral membrane protein family gene gene2788 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02789 S100027_02790 S100027_02790 S100027_02790 2650297 2651082 - Spermidine/putrescine import ATP-binding protein PotA ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3. A. 1. 11. 1) family%3B Contains 1 ABC transporter domain gene gene2789 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02790 S100027_02791 S100027_02791 S100027_02791 2651217 2652101 - UPF0750 membrane protein YqfU Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0750 family gene gene2790 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02791 S100027_02792 S100027_02792 S100027_02792 2652225 2652485 + uncharacterized protein gene gene2791 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02792 S100027_02793 S100027_02793 S100027_02793 2652513 2653406 - Deoxyribonuclease IV DNA damage%3B DNA repair%3B Endonuclease%3B Hydrolase%3B Metal-binding%3B Nuclease%3B Zinc%3B Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin%3B Belongs to the AP endonuclease 2 family%3B KEGG: bsu:BSU25130 deoxyribonuclease IV gene gene2792 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02793 S100027_02794 S100027_02794 S100027_02794 2653418 2654737 - RNA helicase ATP-binding%3B Cytoplasm%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Ribosome biogenesis%3B RNA-binding%3B Stress response%3B DEAD-box RNA helicase that plays a role in 70S ribosome assembly. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures%3B Belongs to the DEAD box helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bsu:BSU25140 ATP-dependent RNA helicase CshB gene gene2793 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02794 S100027_02795 S100027_02795 S100027_02795 2654994 2655641 + uncharacterized protein gene gene2794 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02795 S100027_02796 S100027_02796 ispH ispH 2655762 2656706 + 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3Fe-4S%3B Iron%3B Iron-sulfur%3B Isoprene biosynthesis%3B Metal-binding%3B NADP%3B Oxidoreductase%3B Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP)%3B Belongs to the IspH family%3B KEGG: bsu:BSU25160 4-hydroxy-3-methylbut-2-enyl diphosphate reductase gene gene2795 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02796 S100027_02797 S100027_02797 S100027_02797 2656734 2657855 - GTP cyclohydrolase 1 type 2 like protein Metal-binding%3B Belongs to the GTP cyclohydrolase I type 2/NIF3 family gene gene2796 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02797 S100027_02798 S100027_02798 trmK trmK 2657852 2658565 - tRNA (adenine(22)-N(1))-methyltransferase Cytoplasm%3B Methyltransferase%3B Phosphoprotein%3B S-adenosyl-L-methionine%3B Transferase%3B tRNA processing%3B Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 22 (m1A22) in tRNA%3B Belongs to the TrmK family%3B KEGG: bsq:B657_25180 tRNA (adenine22-N1)-methyltransferase gene gene2797 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02798 S100027_02799 S100027_02799 S100027_02799 2658655 2658939 - Deoxyribonuclease V Cytoplasm%3B DNA damage%3B DNA repair%3B Endonuclease%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nuclease%3B DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA%3B Belongs to the endonuclease V family%3B KEGG: bst:GYO_3975 deoxyribonuclease V%3B overlaps another CDS with the same product name gene gene2798 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02799 S100027_02800 S100027_02800 S100027_02800 2658936 2659379 - Deoxyribonuclease V Cytoplasm%3B DNA damage%3B DNA repair%3B Endonuclease%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nuclease%3B DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA%3B Belongs to the endonuclease V family%3B KEGG: blh:BaLi_c27850 deoxyribonuclease V%3B overlaps another CDS with the same product name gene gene2799 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02800 S100027_02801 S100027_02801 S100027_02801 2659593 2659817 - hypothetical protein gene gene2800 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02801 S100027_02802 S100027_02802 S100027_02802 2660040 2660690 - hypothetical protein gene gene2801 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02802 S100027_02803 S100027_02803 S100027_02803 2660968 2661372 - hypothetical protein gene gene2802 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02803 S100027_02804 S100027_02804 S100027_02804 2661453 2661791 - hypothetical protein gene gene2803 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02804 S100027_02805 S100027_02805 S100027_02805 2661896 2662405 - hypothetical protein gene gene2804 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02805 S100027_02806 S100027_02806 S100027_02806 2662638 2662973 - hypothetical protein gene gene2805 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02806 S100027_02807 S100027_02807 S100027_02807 2662949 2663140 - hypothetical protein gene gene2806 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02807 S100027_02808 S100027_02808 S100027_02808 2663292 2663801 - hypothetical protein gene gene2807 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02808 S100027_02809 S100027_02809 S100027_02809 2663818 2665827 - Putative ribonuclease YwqJ Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Probable toxic component of a toxin-antitoxin (TA) module. The C-terminus may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YwqK%2C but not by antitoxins specific to other toxins with the LXG domain (By similarity)%3B Contains 1 LXG domain gene gene2808 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02809 S100027_02810 S100027_02810 S100027_02810 2665852 2666115 - uncharacterized protein Coiled coil%3B overlaps another CDS with the same product name gene gene2809 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02810 S100027_02811 S100027_02811 S100027_02811 2666115 2666549 - uncharacterized protein Coiled coil%3B overlaps another CDS with the same product name gene gene2810 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02811 S100027_02812 S100027_02812 S100027_02812 2666919 2667278 - Cytochrome c-550 Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Transmembrane%3B Transmembrane helix%3B Transport. gene gene2811 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02812 S100027_02813 S100027_02813 S100027_02813 2667635 2668756 - RNA polymerase sigma factor SigA Cytoplasm%3B DNA-binding%3B Sigma factor%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth%3B Belongs to the sigma-70 factor family. RpoD/SigA subfamily gene gene2812 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02813 S100027_02814 S100027_02814 dnaG dnaG 2668963 2670786 - DNA primase DNA replication%3B DNA-binding%3B DNA-directed RNA polymerase%3B Magnesium%3B Metal-binding%3B Nucleotidyltransferase%3B Primosome%3B Transcription%3B Transferase%3B Zinc%3B Zinc-finger%3B RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication%3B Belongs to the DnaG primase family%3B Contains 1 Toprim domain%3B KEGG: noc:Noc_0044 DNA primase%3B Nucleotidyltransferases gene gene2813 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02814 S100027_02815 S100027_02815 S100027_02815 2670819 2671310 - UPF0178 protein Belongs to the UPF0178 family gene gene2814 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02815 S100027_02816 S100027_02816 S100027_02816 2671575 2672387 - Putative pyruvate%2C phosphate dikinase regulatory protein Kinase%3B Nucleotide-binding%3B Serine/threonine-protein kinase%3B Transferase%3B Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate%2C phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation%3B Belongs to the pyruvate%2C phosphate/water dikinase regulatory protein family. PDRP subfamily gene gene2815 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02816 S100027_02817 S100027_02817 S100027_02817 2672413 2673012 - Transcriptional repressor CcpN DNA-binding%3B Repeat%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcription repressor that binds to the promoter of gapB and pckA genes%2C preventing their expression. Acts as a regulator for catabolite repression of gluconeogenic genes%3B Contains 2 CBS domains%3B Contains 1 HTH deoR-type DNA-binding domain gene gene2816 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02817 S100027_02818 S100027_02818 glyS glyS 2673249 2675288 - Glycine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: pin:Ping_3726 glycyl-tRNA synthetase beta chain%3B overlaps another CDS with the same product name gene gene2817 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02818 S100027_02819 S100027_02819 glyQ glyQ 2675281 2676168 - Glycine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: wbr:WGLp593 glycyl-tRNA synthetase alpha chain%3B overlaps another CDS with the same product name gene gene2818 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02819 S100027_02820 S100027_02820 S100027_02820 2676500 2677270 - DNA repair protein RecO DNA damage%3B DNA recombination%3B DNA repair%3B Involved in DNA repair and RecF pathway recombination%3B Belongs to the RecO family gene gene2819 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02820 S100027_02821 S100027_02821 S100027_02821 2677308 2677451 - uncharacterized protein gene gene2820 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02821 S100027_02822 S100027_02822 S100027_02822 2677613 2678518 - GTPase Era Cell membrane%3B Cytoplasm%3B GTP-binding%3B Membrane%3B Nucleotide-binding%3B Ribosome biogenesis%3B RNA-binding%3B rRNA-binding%3B An essential GTPase that binds both GDP and GTP%2C with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity). Binds both GDP and GTP. Complements an E. coli era disruption mutant%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. Era GTPase family%3B Contains 1 Era-type G (guanine nucleotide-binding) domain%3B Contains 1 KH type-2 domain gene gene2821 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02822 S100027_02823 S100027_02823 S100027_02823 2678499 2678909 - Cytidine deaminase Hydrolase%3B Metal-binding%3B Zinc%3B This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. Belongs to the cytidine and deoxycytidylate deaminase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: bli:BL03673 cytidine deaminase gene gene2822 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02823 S100027_02824 S100027_02824 S100027_02824 2679041 2679421 - Undecaprenol kinase ATP-binding%3B Cell membrane%3B Kinase%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Nucleotide-binding%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Recycling of diacylglycerol produced during the turnover of membrane phospholipid%3B Belongs to the bacterial diacylglycerol kinase family%3B KEGG: bli:BL03672 undecaprenol kinase gene gene2823 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02824 S100027_02825 S100027_02825 S100027_02825 2679399 2679875 - Endoribonuclease YbeY Cytoplasm%3B Endonuclease%3B Hydrolase%3B Metal-binding%3B Nuclease%3B Ribosome biogenesis%3B rRNA processing%3B Zinc%3B Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA%3B Belongs to the endoribonuclease YbeY family gene gene2824 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02825 S100027_02826 S100027_02826 S100027_02826 2679872 2682022 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2825 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02826 S100027_02827 S100027_02827 S100027_02827 2682091 2683050 - PhoH-like protein ATP-binding%3B Cytoplasm%3B Nucleotide-binding%3B Belongs to the PhoH family gene gene2826 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02827 S100027_02828 S100027_02828 S100027_02828 2683047 2684243 - uncharacterized protein Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B To B. megaterium SpoIV gene gene2827 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02828 S100027_02829 S100027_02829 S100027_02829 2684261 2684542 - uncharacterized protein gene gene2828 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02829 S100027_02830 S100027_02830 S100027_02830 2684598 2685047 - uncharacterized protein Cell membrane%3B Coiled coil%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2829 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02830 S100027_02831 S100027_02831 S100027_02831 2685077 2686069 - UPF0365 protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0365 family gene gene2830 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02831 S100027_02832 S100027_02832 S100027_02832 2686093 2687412 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2831 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02832 S100027_02833 S100027_02833 S100027_02833 2687557 2688003 - uncharacterized protein gene gene2832 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02833 S100027_02834 S100027_02834 S100027_02834 2688018 2688191 - 30S ribosomal protein S21 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein S21P family gene gene2833 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02834 S100027_02835 S100027_02835 S100027_02835 2688377 2689312 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B To E. coli YjbB gene gene2834 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02835 S100027_02836 S100027_02836 deoC deoC 2689332 2690003 - Deoxyribose-phosphate aldolase Cytoplasm%3B Lyase%3B Schiff base%3B Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate%3B Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily%3B KEGG: bli:BL02102 deoxyribose-phosphate aldolase gene gene2835 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02836 S100027_02837 S100027_02837 mtaB mtaB 2690094 2691449 - tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase 4Fe-4S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B S-adenosyl-L-methionine%3B Transferase%3B tRNA processing%3B Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A)%2C leading to the formation of 2- methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine%3B Belongs to the methylthiotransferase family. MtaB subfamily%3B Contains 1 MTTase N-terminal domain%3B Contains 1 TRAM domain%3B KEGG: bsu:BSU25430 threonylcarbamoyladenosine tRNA methylthiotransferase MtaB gene gene2836 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02837 S100027_02838 S100027_02838 rsmE rsmE 2691452 2692219 - 16S rRNA (uracil(1498)-N(3))-methyltransferase Cytoplasm%3B Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)%3B Belongs to the RNA methyltransferase RsmE family%3B KEGG: bli:BL02100 16S rRNA (uracil1498-N3)-methyltransferase gene gene2837 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02838 S100027_02839 S100027_02839 prmA prmA 2692243 2693178 - Ribosomal protein L11 methyltransferase Cytoplasm%3B Methyltransferase%3B Transferase%3B Methylates ribosomal protein L11%3B Belongs to the methyltransferase superfamily. PrmA family%3B KEGG: bli:BL02099 ribosomal protein L11 methyltransferase%3B Methyltransferases gene gene2838 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02839 S100027_02840 S100027_02840 S100027_02840 2693202 2694329 - Chaperone protein DnaJ Chaperone%3B Cytoplasm%3B DNA replication%3B Metal-binding%3B Repeat%3B Stress response%3B Zinc%3B Zinc-finger%3B Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins%2C also in an autonomous%2C DnaK-independent fashion. Unfolded proteins bind initially to Dna%3B upon interaction with the DnaJ-bound protein%2C DnaK hydrolyzes its bound ATP%2C resulting in the formation of a stable complex. GrpE releases ADP from Dna%3B ATP binding to DnaK triggers the release of the substrate protein%2C thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ%2C DnaK and GrpE are required for fully efficient folding. Also involved%2C together with DnaK and GrpE%2C in the DNA replication of plasmids through activation of initiation proteins%3B Belongs to the DnaJ family%3B Contains 1 CR-type zinc finger%3B Contains 1 J domain gene gene2839 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02840 S100027_02841 S100027_02841 S100027_02841 2694512 2696350 - Chaperone protein DnaK ATP-binding%3B Chaperone%3B Nucleotide-binding%3B Phosphoprotein%3B Stress response%3B Acts as a chaperone%3B Belongs to the heat shock protein 70 family gene gene2840 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02841 S100027_02842 S100027_02842 S100027_02842 2696374 2696958 - Protein GrpE Chaperone%3B Cytoplasm%3B Stress response%3B Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins%2C in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to Dna%3B upon interaction with the DnaJ-bound protein%2C DnaK hydrolyzes its bound ATP%2C resulting in the formation of a stable complex. GrpE releases ADP from Dna%3B ATP binding to DnaK triggers the release of the substrate protein%2C thus completing the reaction cycle. Several rounds of ATP- dependent interactions between DnaJ%2C DnaK and GrpE are required for fully efficient folding%3B Belongs to the GrpE family gene gene2841 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02842 S100027_02843 S100027_02843 S100027_02843 2697037 2698068 - Heat-inducible transcription repressor HrcA Repressor%3B Stress response%3B Transcription%3B Transcription regulation%3B Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons%3B Belongs to the HrcA family gene gene2842 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02843 S100027_02844 S100027_02844 S100027_02844 2698149 2699288 - Coproporphyrinogen dehydrogenase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase%3B Porphyrin biosynthesis%3B S-adenosyl-L-methionine%3B Involved in the biosynthesis of porphyrin-containing compound%3B Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemN-like subfamily%3B KEGG: bli:BL02093 oxygen-independent coproporphyrinogen III oxidase gene gene2843 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02844 S100027_02845 S100027_02845 S100027_02845 2699348 2701186 - Elongation factor Cell membrane%3B GTP-binding%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Protein biosynthesis%3B Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction%2C by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex%2C thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene2844 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02845 S100027_02846 S100027_02846 S100027_02846 2701332 2701655 - uncharacterized protein gene gene2845 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02846 S100027_02847 S100027_02847 S100027_02847 2701671 2702876 - Stage II sporulation protein Sporulation. gene gene2846 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02847 S100027_02848 S100027_02848 S100027_02848 2702995 2704101 - GPR endopeptidase Hydrolase%3B Protease%3B Zymogen%3B Initiates the rapid degradation of small%2C acid-soluble proteins during spore germination%3B Belongs to the peptidase A25 family%3B KEGG: bli:BL02089 spore protease gene gene2847 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02848 S100027_02849 S100027_02849 S100027_02849 2704306 2704572 + 30S ribosomal protein S20 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Binds directly to 16S ribosomal RNA%3B Belongs to the ribosomal protein S20P family gene gene2848 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02849 S100027_02850 S100027_02850 holA holA 2704634 2705698 - DNA-directed DNA polymerase KEGG: bld:BLi02748 DNA polymerase III subunit delta gene gene2849 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02850 S100027_02851 S100027_02851 S100027_02851 2705907 2706038 + putative membrane protein YqzM Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2850 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02851 S100027_02852 S100027_02852 S100027_02852 2706063 2708450 - ComE operon protein Cell membrane%3B Competence%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The comE operon is required for the binding and uptake of transforming DNA. ComEC is required for internalization but is dispensable for DNA binding. To H. influenzae REC2%2C N. gonorrhoeae ComA and E. coli YcaI gene gene2851 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02852 S100027_02853 S100027_02853 S100027_02853 2708454 2709023 - dCMP deaminase Hydrolase%3B Metal-binding%3B Zinc%3B Dispensable for transformability. Belongs to the cytidine and deoxycytidylate deaminase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: bsu:BSU25580 dCMP deaminase gene gene2852 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02853 S100027_02854 S100027_02854 S100027_02854 2709092 2709721 - ComE operon protein Cell membrane%3B Competence%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Needed for both DNA binding and transport. It is absolutely required for the uptake of transforming DNA but not for binding. Its role in binding may be indirect. Contains 2 HhH domains gene gene2853 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02854 S100027_02855 S100027_02855 S100027_02855 2709805 2710626 + ComE operon protein Dispensable for transformability. Not known if it can act as a pyrroline-5-carboxylate reductase. Belongs to the pyrroline-5-carboxylate reductase family gene gene2854 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02855 S100027_02856 S100027_02856 ubiG ubiG 2710696 2711451 - 2-polyprenyl-6-hydroxyphenol methylase Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B May be a S-adenosyl-L-methionine (SAM)-dependent methyltransferase. Belongs to the methyltransferase superfamily%3B KEGG: fil:BN1229_v1_1253 2-polyprenyl-6-hydroxyphenyl methylase / 3-demethylubiquinone-9 3-methyltransferase gene gene2855 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02856 S100027_02857 S100027_02857 S100027_02857 2711448 2711804 - Ribosomal silencing factor RsfS Cytoplasm%3B Repressor%3B Translation regulation%3B Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN)%2C blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes%2C thus repressing translation%3B Belongs to the Iojap/RsfS family gene gene2856 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02857 S100027_02858 S100027_02858 S100027_02858 2711818 2712381 - Nicotinate-nucleotide adenylyltransferase Contains 1 HD domain%3B KEGG: ccel:CCDG5_0474 nicotinate-nucleotide adenylyltransferase%3B overlaps another CDS with the same product name gene gene2857 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02858 S100027_02859 S100027_02859 S100027_02859 2712371 2712940 - Nicotinate-nucleotide adenylyltransferase ATP-binding%3B NAD%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Pyridine nucleotide biosynthesis%3B Transferase%3B Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)%3B Belongs to the NadD family%3B KEGG: nma:NMA0416 nicotinate-nucleotide adenylyltransferase%3B overlaps another CDS with the same product name gene gene2858 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02859 S100027_02860 S100027_02860 S100027_02860 2712959 2713249 - putative RNA-binding protein YqeI RNA-binding%3B Contains 1 CRM domain gene gene2859 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02860 S100027_02861 S100027_02861 aroE aroE 2713243 2714079 - Shikimate dehydrogenase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B NADP%3B Oxidoreductase%3B Involved in the biosynthesis of the chorismate%2C which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)%3B Belongs to the shikimate dehydrogenase family%3B KEGG: bli:BL02079 shikimate dehydrogenase gene gene2860 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02861 S100027_02862 S100027_02862 S100027_02862 2714099 2715199 - uncharacterized protein GTP-binding%3B Nucleotide-binding%3B Binds GTP and GDP. Belongs to the TRAFAC class YlqF/YawG GTPase family%3B Contains 1 CP-type G (guanine nucleotide-binding) domain gene gene2861 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02862 S100027_02863 S100027_02863 S100027_02863 2715203 2715721 - uncharacterized protein gene gene2862 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02863 S100027_02864 S100027_02864 S100027_02864 2716347 2716502 - hypothetical protein gene gene2863 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02864 S100027_02865 S100027_02865 S100027_02865 2716580 2717311 - putative lipoprotein YqeF Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal. gene gene2864 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02865 S100027_02866 S100027_02866 S100027_02866 2717455 2718216 - putative N-acetyltransferase YdfB Acyltransferase%3B Transferase%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK4362 null%3B Transferring groups other than amino-acyl groups gene gene2865 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02866 S100027_02867 S100027_02867 S100027_02867 2718248 2718622 - uncharacterized protein gene gene2866 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02867 S100027_02868 S100027_02868 S100027_02868 2718926 2721865 + Formate dehydrogenase 2Fe-2S%3B 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Molybdenum%3B NAD%3B Oxidoreductase%3B Repeat%3B In the C-terminal sectio%3B belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 2Fe-2S ferredoxin-type domain%3B Contains 2 4Fe-4S ferredoxin-type domains%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: bli:BL02109 formate dehydrogenase major subunit gene gene2867 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02868 S100027_02869 S100027_02869 S100027_02869 2721887 2722366 + uncharacterized protein To A. fulgidus AF1717 gene gene2868 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02869 S100027_02870 S100027_02870 S100027_02870 2722442 2722678 - hypothetical protein gene gene2869 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02870 S100027_02871 S100027_02871 S100027_02871 2722913 2723638 + RNA polymerase sigma-K factor DNA-binding%3B Sigma factor%3B Sporulation%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the mother cell. Belongs to the sigma-70 factor family gene gene2870 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02871 S100027_02872 S100027_02872 S100027_02872 2723933 2724883 - hypothetical protein gene gene2871 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02872 S100027_02873 S100027_02873 S100027_02873 2725555 2727360 - Subtilin transport ATP-binding protein SpaT ATP-binding%3B Bacteriocin transport%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably implicated in the export process of the lantibiotic subtilin. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene2872 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02873 S100027_02874 S100027_02874 S100027_02874 2727612 2728157 - hypothetical protein gene gene2873 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02874 S100027_02875 S100027_02875 S100027_02875 2728154 2728684 - hypothetical protein gene gene2874 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02875 S100027_02876 S100027_02876 S100027_02876 2728874 2730031 + Stage II sporulation protein Sporulation. gene gene2875 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02876 S100027_02877 S100027_02877 S100027_02877 2730454 2730675 - hypothetical protein gene gene2876 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02877 S100027_02878 S100027_02878 S100027_02878 2730997 2731311 + RNA polymerase sigma-28 factor DNA-binding%3B Sigma factor%3B Sporulation%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor directs the transcription of crystal protein genes%2C a sporulation-regulated event (By similarity)%3B Belongs to the sigma-70 factor family gene gene2877 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02878 S100027_02879 S100027_02879 S100027_02879 2731764 2733614 + hypothetical protein gene gene2878 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02879 S100027_02880 S100027_02880 S100027_02880 2733810 2734493 - hypothetical protein gene gene2879 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02880 S100027_02881 S100027_02881 S100027_02881 2734666 2737176 - hypothetical protein gene gene2880 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02881 S100027_02882 S100027_02882 S100027_02882 2737525 2737839 + RNA polymerase sigma-28 factor DNA-binding%3B Sigma factor%3B Sporulation%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor directs the transcription of crystal protein genes%2C a sporulation-regulated event (By similarity)%3B Belongs to the sigma-70 factor family gene gene2881 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02882 S100027_02883 S100027_02883 S100027_02883 2738218 2738784 - hypothetical protein gene gene2882 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02883 S100027_02884 S100027_02884 S100027_02884 2739514 2740194 - Methionine import ATP-binding protein MetN Amino-acid transport%3B ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Methionine importer (TC 3. A. 1. 24) family%3B Contains 1 ABC transporter domain gene gene2883 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02884 S100027_02885 S100027_02885 S100027_02885 2740191 2741294 - Putative hemin transport system permease protein HrtB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the ABC-4 integral membrane protein family. HrtB subfamily gene gene2884 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02885 S100027_02886 S100027_02886 S100027_02886 2741397 2742776 - Heme sensor protein HssS ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Virulence%3B Member of the two-component regulatory system HssS/HssR involved in intracellular heme homeostasis and tempering of staphylococcal virulence. HssS functions as a heme sensor histidine kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to an aspartate residue of HssR. HssR/HssS activates the expression of hrtAB%2C an efflux pump%2C in response to extracellular heme%2C hemin%2C hemoglobin or blood (By similarity)%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: lwe:lwe2532 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene2885 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02886 S100027_02887 S100027_02887 S100027_02887 2742773 2743447 - Response regulator ArlR Activator%3B Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Repressor%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Virulence%3B Member of the two-component regulatory system ArlS/ArlR involved in the regulation of adhesion%2C autolysis%2C multidrug resistance and virulence%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2886 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02887 S100027_02888 S100027_02888 S100027_02888 2745515 2745634 - hypothetical protein gene gene2887 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02888 S100027_02889 S100027_02889 S100027_02889 2746071 2746385 + RNA polymerase sigma-28 factor DNA-binding%3B Sigma factor%3B Sporulation%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor directs the transcription of crystal protein genes%2C a sporulation-regulated event (By similarity)%3B Belongs to the sigma-70 factor family gene gene2888 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02889 S100027_02890 S100027_02890 S100027_02890 2746437 2746967 - hypothetical protein gene gene2889 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02890 S100027_02891 S100027_02891 S100027_02891 2747050 2747574 - putative N-acetyltransferase YuaI Acyltransferase%3B Transferase%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: tth:TTC0848 null%3B Transferring groups other than amino-acyl groups gene gene2890 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02891 S100027_02892 S100027_02892 S100027_02892 2748825 2749199 - UPF0715 membrane protein YwlA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0715 family gene gene2891 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02892 S100027_02893 S100027_02893 S100027_02893 2749255 2750604 + hypothetical protein gene gene2892 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02893 S100027_02894 S100027_02894 S100027_02894 2751167 2752477 - hypothetical protein gene gene2893 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02894 S100027_02895 S100027_02895 S100027_02895 2753139 2753879 - hypothetical protein gene gene2894 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02895 S100027_02896 S100027_02896 S100027_02896 2754138 2755571 - Hydroxyacylglutathione hydrolase Belongs to the UPF0033 family%3B Contains 1 rhodanese domain%3B KEGG: bst:GYO_2875 hydroxyacylglutathione hydrolase gene gene2895 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02896 S100027_02897 S100027_02897 S100027_02897 2755644 2756843 - Sulfide:quinone oxidoreductase%2C mitochondrial FAD%3B Flavoprotein%3B Mitochondrion%3B Oxidoreductase%3B Quinone%3B Transit peptide%3B Catalyzes the oxidation of hydrogen sulfide%2C with the help of a quinone%3B Belongs to the SQRD family%3B KEGG: bst:GYO_2876 sulfide:quinone oxidoreductase%3B With a quinone or similar compound as acceptor gene gene2896 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02897 S100027_02898 S100027_02898 S100027_02898 2757004 2757648 - Chemotaxis response regulator protein-glutamate methylesterase Chemotaxis%3B Cytoplasm%3B Hydrolase%3B Phosphoprotein%3B Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene2897 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02898 S100027_02899 S100027_02899 nreB nreB 2757623 2758702 - Histidine kinase 4Fe-4S%3B ATP-binding%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Kinase%3B Metal-binding%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Two-component regulatory system%3B Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated%2C in the absence of oxygen%2C probably at the conserved histidine residue%2C and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons%2C as well as the putative nitrate transporter gene narT%3B Contains 1 histidine kinase domain%3B KEGG: bbe:BBR47_03990 two-component system%2C NarL family%2C sensor histidine kinase NreB gene gene2898 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02899 S100027_02900 S100027_02900 S100027_02900 2758724 2759059 - Thioredoxin-like protein YdfQ Disulfide bond%3B Redox-active center%3B Contains 1 thioredoxin domain gene gene2899 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02900 S100027_02901 S100027_02901 S100027_02901 2759081 2759863 - UPF0721 transmembrane protein YrkJ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0721 family gene gene2900 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02901 S100027_02902 S100027_02902 tusA tusA 2759918 2760145 - UPF0033 protein YrkI Belongs to the UPF0033 family%3B KEGG: afe:Lferr_2187 tRNA 2-thiouridine synthesizing protein A%3B Sulfurtransferases gene gene2901 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02902 S100027_02903 S100027_02903 S100027_02903 2760173 2761303 - Hydroxyacylglutathione hydrolase Contains 1 rhodanese domain%3B KEGG: mba:Mbar_A2729 hydroxyacylglutathione hydrolase gene gene2902 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02903 S100027_02904 S100027_02904 S100027_02904 2761404 2761976 - UPF0033 protein YrkI Belongs to the UPF0033 family%3B KEGG: afe:Lferr_2187 tRNA 2-thiouridine synthesizing protein A%3B Sulfurtransferases gene gene2903 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02904 S100027_02905 S100027_02905 S100027_02905 2762083 2762565 - uncharacterized protein KEGG: gca:Galf_0318 tRNA 2-thiouridine synthesizing protein A%3B Sulfurtransferases gene gene2904 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02905 S100027_02906 S100027_02906 S100027_02906 2762728 2762988 - Copper-sensing transcriptional repressor CsoR Copper%3B Cytoplasm%3B DNA-binding%3B Metal-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Copper-sensitive repressor that has a key role in copper homeostasis. Negatively regulates expression of the copZA operon and of ycnJ. In the absence of copper ions%2C binds with high affinity to the copZA promoter and represses the transcription. In the presence of copper ions%2C CsoR binds Cu(1+)%2C which significantly decreases its DNA binding affinity and leads to the transcription of the genes%3B Belongs to the CsoR family gene gene2905 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02906 S100027_02907 S100027_02907 S100027_02907 2763463 2764059 - hypothetical protein gene gene2906 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02907 S100027_02908 S100027_02908 S100027_02908 2764104 2764811 - uncharacterized protein gene gene2907 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02908 S100027_02909 S100027_02909 S100027_02909 2766179 2767021 - hypothetical protein gene gene2908 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02909 S100027_02910 S100027_02910 S100027_02910 2767530 2767775 - Putative membrane protein insertion efficiency factor Cell membrane%3B Membrane%3B Could be involved in insertion of integral membrane proteins into the membrane%3B Belongs to the UPF0161 family gene gene2909 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02910 S100027_02911 S100027_02911 S100027_02911 2768342 2768446 - hypothetical protein gene gene2910 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02911 S100027_02912 S100027_02912 hxlB hxlB 2768607 2769164 - 6-phospho-3-hexuloisomerase Carbohydrate metabolism%3B Isomerase%3B Catalyzes the isomerization between 3-hexulose 6- phosphate and fructose 6-phosphate%3B Belongs to the SIS family. PHI subfamily%3B Contains 1 SIS domain%3B KEGG: blh:BaLi_c28990 6-phospho-3-hexuloisomerase gene gene2911 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02912 S100027_02913 S100027_02913 hxlA hxlA 2769161 2769793 - 3-hexulose-6-phosphate synthase Carbohydrate metabolism%3B Lyase%3B One-carbon metabolism%3B Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate%3B Belongs to the HPS/KGPDC family. HPS subfamily%3B KEGG: eum:ECUMN_2963 3-hexulose-6-phosphate synthase gene gene2912 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02913 S100027_02914 S100027_02914 S100027_02914 2769981 2770328 - HTH-type transcriptional activator HxlR Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Positive regulator of hxlAB expression. Contains 1 HTH hxlR-type DNA-binding domain gene gene2913 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02914 S100027_02915 S100027_02915 S100027_02915 2770622 2771680 + Fatty acid desaturase Cell membrane%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsaturated fatty acids%3B Belongs to the fatty acid desaturase family%3B KEGG: bsu:BSU19180 omega-6 fatty acid desaturase (delta-12 desaturase)%3B With oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water gene gene2914 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02915 S100027_02916 S100027_02916 desK desK 2771801 2772913 + Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system DesR/DesK%2C responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase. Acts as a sensor of the membrane fluidity. Probably activates DesR by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bsr:I33_2153 two-component system%2C NarL family%2C sensor histidine kinase DesK gene gene2915 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02916 S100027_02917 S100027_02917 S100027_02917 2772932 2773531 + Transcriptional regulatory protein DesR Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system DesR/DesK%2C responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase%3B Contains 1 HTH luxR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2916 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02917 S100027_02918 S100027_02918 S100027_02918 2773607 2774656 - Thioredoxin-disulfide reductase FAD%3B Flavoprotein%3B NADP%3B Oxidoreductase%3B Belongs to the ferredoxin--NADP reductase type 2 family%3B KEGG: bli:BL02042 thioredoxin reductase (NADPH) gene gene2917 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02918 S100027_02919 S100027_02919 S100027_02919 2774946 2776568 + Nickel-binding periplasmic protein Nickel%3B Periplasm%3B Signal%3B Transport%3B Involved in a nickel transport system%2C probably represents the nickel binder. Belongs to the bacterial solute-binding protein 5 family gene gene2918 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02919 S100027_02920 S100027_02920 S100027_02920 2776578 2777522 + Putative oligopeptide transport system permease protein oppB2 Cell membrane%3B Membrane%3B Peptide transport%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of a transport system that may be involved in oligopeptide uptake. Probably responsible for the translocation of the substrate across the membrane. Important for S. aureus growth and survival during the infection process (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2919 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02920 S100027_02921 S100027_02921 S100027_02921 2777519 2778352 + Oligopeptide transport system permease protein OppC Cell membrane%3B Competence%3B Membrane%3B Peptide transport%3B Protein transport%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system for oligopeptide%3B probably responsible for the translocation of the substrate across the membrane. Also required for sporulation and competence. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2920 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02921 S100027_02922 S100027_02922 nikD nikD 2778368 2779186 + Nickel-transporting ATPase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Peptide transport%3B Protein transport%3B Transport%3B Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: bli:BL02421 nickel transport system ATP-binding protein gene gene2921 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02922 S100027_02923 S100027_02923 S100027_02923 2779183 2780046 + putative ABC transporter ATP-binding protein YcbN ATP-binding%3B Nucleotide-binding%3B Transport%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene2922 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02923 S100027_02924 S100027_02924 S100027_02924 2780359 2781195 + putative HTH-type transcriptional regulator YdfL DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH merR-type DNA-binding domain gene gene2923 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02924 S100027_02925 S100027_02925 S100027_02925 2781252 2782607 + Multidrug export protein MepA Antibiotic resistance%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Multidrug resistance efflux protein%3B Belongs to the multi antimicrobial extrusion (MATE) (TC 2. A. 66. 1) family. MepA subfamily gene gene2924 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02925 S100027_02926 S100027_02926 S100027_02926 2782921 2783928 + HTH-type transcriptional regulator GadX Activator%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Virulence%3B Positively regulates the expression of about fifteen genes involved in acid resistance such as gadA%2C gadB and gadC. Depending on the conditions (growth phase and medium)%2C can repress gadW (By similarity). Negatively regulates perA expression in acidic conditions and positively regulates it in alkaline conditions%3B Contains 1 HTH araC/xylS-type DNA-binding domain gene gene2925 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02926 S100027_02927 S100027_02927 S100027_02927 2783946 2784740 + 3-oxoacyl-[acyl-carrier-protein] reductase Acetylation%3B Alternative splicing%3B Mitochondrion%3B Nucleus%3B Oxidoreductase%3B Phosphoprotein%3B Polymorphism%3B Transit peptide%3B Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3%2C4-Hexanedione%2C 2%2C3-Heptanedione and 1-Phenyl-1%2C2- propanedione as substrates. No reductase activity is displayed in vitro with steroids%2C retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation%2C leading to p53/TP53 stabilization and increased transcription activity%2C resulting in the accumulation of MDM2 and CDKN1A/p21%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: pao:Pat9b_1844 3-oxoacyl-(acyl-carrier protein) reductase gene gene2926 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02927 S100027_02928 S100027_02928 phoN phoN 2784852 2786642 - Acid phosphatase Hydrolase%3B Periplasm%3B Signal%3B Belongs to the class A bacterial acid phosphatase family%3B KEGG: sty:STY4519 acid phosphatase (class A) gene gene2927 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02928 S100027_02929 S100027_02929 S100027_02929 2786916 2787755 - Isoprenylcysteine alpha-carbonyl methylesterase ICME Alternative splicing%3B Endoplasmic reticulum%3B Golgi apparatus%3B Hydrolase%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the demethylation of isoprenylcysteine methylesters. In vitro%2C is specific for N-acetyl-S-farnesyl-L- cysteine methyl ester (AFCme) and has low activity toward N- acetyl-S-geranyl-L-cysteine methyl ester (AGCme). Acts as a positive regulator of ABA signaling. May be involved in the demethylation and inactivation of isoprenylated negative regulators of abscisic acid (ABA) signaling. Carboxyl methylation is a reversible and potentially regulated step in the post- translational modification of prenylated proteins%3B Belongs to the AB hydrolase superfamily. Isoprenylcysteine methylesterase family%3B KEGG: pat:Patl_0510 para-nitrobenzyl esterase%3B Carboxylic ester hydrolases gene gene2928 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02929 S100027_02930 S100027_02930 S100027_02930 2788169 2789404 - Cytochrome P450 Heme%3B Iron%3B Metal-binding%3B Monooxygenase%3B Oxidoreductase%3B Belongs to the cytochrome P450 family%3B KEGG: ban:BA_2627 null%3B Acting on paired donors%2C with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O(2) gene gene2929 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02930 S100027_02931 S100027_02931 S100027_02931 2789802 2790689 - UPF0721 transmembrane protein YtnM Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0721 family gene gene2930 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02931 S100027_02932 S100027_02932 S100027_02932 2790998 2791378 + hypothetical protein gene gene2931 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02932 S100027_02933 S100027_02933 S100027_02933 2791565 2792362 + 3-oxoacyl-[acyl-carrier-protein] reductase Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bld:BLi02826 3-oxoacyl-(acyl-carrier protein) reductase gene gene2932 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02933 S100027_02934 S100027_02934 S100027_02934 2792400 2794433 - Fructan beta-fructosidase Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Secreted%3B Signal%3B Exo-fructosidase that can hydrolyze both levan and inulin%2C leading to the production of free fructose. Is also able to hydrolyze sucrose and to a small extent raffinose%2C but not melezitose%2C stachylose%2C cellobiose%2C maltose%2C and lactose%3B Belongs to the glycosyl hydrolase 32 family%3B KEGG: bsu:BSU27030 fructan beta-fructosidase gene gene2933 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02934 S100027_02935 S100027_02935 S100027_02935 2794554 2795381 - Fructose permease IID component Cell membrane%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in fructose transport. Contains 1 PTS EIID domain gene gene2934 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02935 S100027_02936 S100027_02936 S100027_02936 2795403 2796206 - Fructose permease IIC component Cell membrane%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in fructose transport. Contains 1 PTS EIIC type-4 domain gene gene2935 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02936 S100027_02937 S100027_02937 levE levE 2796225 2796716 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cytoplasm%3B Kinase%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport. LevD and LevE act as negative regulators of the levanase operon. They may be involved in a PTS-mediated phosphorylation of a regulator. Contains 1 PTS EIIB type-4 domain%3B KEGG: kox:KOX_13535 PTS system%2C fructose-specific IIB component%3B overlaps another CDS with the same product name gene gene2936 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02937 S100027_02938 S100027_02938 agaF agaF 2796716 2797153 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cytoplasm%3B Kinase%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport. LevD and LevE act as negative regulators of the levanase operon. They may be involved in a PTS-mediated phosphorylation of a regulator. Contains 1 PTS EIIA type-4 domain%3B KEGG: ece:Z4488 PTS system%2C N-acetylgalactosamine-specific IIA component%3B overlaps another CDS with the same product name gene gene2937 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02938 S100027_02939 S100027_02939 S100027_02939 2797355 2799295 - Transcriptional regulatory protein LevR Activator%3B ATP-binding%3B DNA-binding%3B Kinase%3B Nucleotide-binding%3B Phosphoprotein%3B Repeat%3B Transcription%3B Transcription regulation%3B Transferase%3B Involved in positive regulation of the levanase operon which comprises the levDEFG genes for a fructose PTS system%2C and sacA for levanase. Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains%3B Contains 1 PTS EIIA type-4 domain%3B Contains 1 sigma-54 factor interaction domain gene gene2938 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02939 S100027_02940 S100027_02940 S100027_02940 2799381 2799719 - Transcriptional regulatory protein LevR Activator%3B ATP-binding%3B DNA-binding%3B Kinase%3B Nucleotide-binding%3B Phosphoprotein%3B Repeat%3B Transcription%3B Transcription regulation%3B Transferase%3B Involved in positive regulation of the levanase operon which comprises the levDEFG genes for a fructose PTS system%2C and sacA for levanase. Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains%3B Contains 1 PTS EIIA type-4 domain%3B Contains 1 sigma-54 factor interaction domain gene gene2939 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02940 S100027_02941 S100027_02941 S100027_02941 2800040 2800504 - uncharacterized protein Signal. gene gene2940 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02941 S100027_02942 S100027_02942 S100027_02942 2800625 2800885 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2941 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02942 S100027_02943 S100027_02943 catA catA 2800953 2801603 - Chloramphenicol O-acetyltransferase Acyltransferase%3B Antibiotic resistance%3B Plasmid%3B Transferase%3B This enzyme is an effector of chloramphenicol resistance in bacteria. Belongs to the chloramphenicol acetyltransferase family%3B KEGG: bli:BL03127 chloramphenicol O-acetyltransferase type A gene gene2942 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02943 S100027_02944 S100027_02944 adaA adaA 2801818 2802378 + Bifunctional transcriptional activator/DNA repair enzyme AdaA Activator%3B DNA damage%3B DNA repair%3B DNA-binding%3B Metal-binding%3B Methyltransferase%3B Transcription%3B Transcription regulation%3B Transferase%3B Zinc%3B Is involved in the adaptive response to alkylation damage in DNA caused by alkylating agents. Repairs the methylphosphotriester lesions in DNA by a direct and irreversible transfer of the methyl group to one of its own cysteine residues. The methylation of AdaA by methylphosphotriesters in DNA leads to its activation as a transcriptional regulator that activates the transcription of the ada operon which consists of adaA and adaB%2C and of the adjacent gene alkA. Contains 1 HTH araC/xylS-type DNA-binding domain%3B KEGG: bli:BL05281 AraC family transcriptional regulator%2C regulatory protein of adaptative response / methylphosphotriester-DNA alkyltransferase methyltransferase%3B Methyltransferases gene gene2943 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02944 S100027_02945 S100027_02945 adaB adaB 2802383 2802910 + Methylated-DNA--[protein]-cysteine S-methyltransferase DNA damage%3B DNA repair%3B Methyltransferase%3B Transferase%3B Is involved in the adaptive response to alkylation damage in DNA caused by alkylating agents. Repairs O6- methylguanine residues in alkylated DNA by a direct and irreversible transfer of the methyl group from the base to one of its own cysteine residues%3B Belongs to the MGMT family%3B KEGG: bli:BL00477 methylated-DNA-(protein)-cysteine S-methyltransferase gene gene2944 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02945 S100027_02946 S100027_02946 akr1 akr1 2802944 2803792 - Aldehyde reductase NADP%3B Oxidoreductase%3B Reduces glyoxal and methylglyoxal. Is not involved in the vitamin B6 biosynthesis%3B Belongs to the aldo/keto reductase family%3B KEGG: nce:NCER_101329 aldehyde reductase gene gene2945 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02946 S100027_02947 S100027_02947 S100027_02947 2803822 2805057 - putative MFS-type transporter YtbD Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene2946 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02947 S100027_02948 S100027_02948 S100027_02948 2805214 2805591 + putative HTH-type transcriptional regulator YtcD DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH hxlR-type DNA-binding domain gene gene2947 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02948 S100027_02949 S100027_02949 pepE pepE 2805611 2806276 + Dipeptidase E Cytoplasm%3B Dipeptidase%3B Hydrolase%3B Protease%3B Serine protease%3B Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids%3B Belongs to the peptidase S51 family%3B KEGG: bli:BL00475 dipeptidase E gene gene2948 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02949 S100027_02950 S100027_02950 hemD hemD 2806587 2807414 - Uroporphyrinogen-III synthase KEGG: bsu:BSU12230 uroporphyrinogen-III synthase gene gene2949 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02950 S100027_02951 S100027_02951 S100027_02951 2807522 2808466 + hypothetical protein gene gene2950 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02951 S100027_02952 S100027_02952 S100027_02952 2808509 2809465 - Iron(3+)-hydroxamate-binding protein YxeB Cell membrane%3B Ion transport%3B Iron%3B Iron transport%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B Part of the ABC transporter complex FhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Partially required for the transport of desferrioxamine%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene2951 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02952 S100027_02953 S100027_02953 S100027_02953 2809543 2810442 - HTH-type transcriptional regulator CfxR Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Trans-acting transcriptional regulator of RuBisCO genes (cfxLS) expression. Contains 1 HTH lysR-type DNA-binding domain gene gene2952 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02953 S100027_02954 S100027_02954 S100027_02954 2810563 2811780 + putative transporter Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene2953 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02954 S100027_02955 S100027_02955 S100027_02955 2811929 2812312 + hypothetical protein gene gene2954 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02955 S100027_02956 S100027_02956 S100027_02956 2812337 2815561 - Unspecific monooxygenase Cytoplasm%3B Electron transport%3B FAD%3B Flavoprotein%3B FMN%3B Heme%3B Iron%3B Metal-binding%3B Monooxygenase%3B Multifunctional enzyme%3B NADP%3B Oxidoreductase%3B Transport%3B Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of a range of medium to long-chain fatty acids%2C with a preference for long-chain unsaturated and branched-chain fatty acids over saturated fatty acids. Hydroxylation of myristic acid occurs mainly at the omega-2 and omega-3 positions%2C in approximately equal proportions. Also displays a NADPH-dependent reductase activity in the C-terminal domain%2C which allows electron transfer from NADPH to the heme iron of the cytochrome P450 N- terminal domain%3B In the N-terminal sectio%3B belongs to the cytochrome P450 family%3B Contains 1 FAD-binding FR-type domain%3B Contains 1 flavodoxin-like domain%3B KEGG: bli:BL02398 cytochrome P450 / NADPH-cytochrome P450 reductase gene gene2955 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02956 S100027_02957 S100027_02957 S100027_02957 2815596 2816171 - HTH-type transcriptional repressor FatR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Negatively regulates the transcription of the fatR-cypB operon. Is displaced from its operator by a range of fatty acids such as oleate%2C linoleate and phytanate%2C thereby allowing transcription of the fatR-cypB operon%3B Contains 1 HTH tetR-type DNA-binding domain gene gene2956 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02957 S100027_02958 S100027_02958 wprA wprA 2816435 2819578 - Cell wall-associated protease Cell wall%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Protease%3B Secreted%3B Serine protease%3B Signal%3B Zymogen%3B CWBP52 is a serine-type protease that could be involved in proteoglycan peptide bridges%3B Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bld:BLi02850 cell wall-associated protease%3B Serine endopeptidases gene gene2957 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02958 S100027_02959 S100027_02959 S100027_02959 2819750 2820355 - Demethylmenaquinone methyltransferase Menaquinone biosynthesis%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family%3B KEGG: age:AA314_00425 demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1%2C4-benzoquinol methylase gene gene2958 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02959 S100027_02960 S100027_02960 S100027_02960 2820632 2820781 + hypothetical protein gene gene2959 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02960 S100027_02961 S100027_02961 S100027_02961 2821198 2821347 - uncharacterized protein gene gene2960 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02961 S100027_02962 S100027_02962 S100027_02962 2821755 2821988 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2961 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02962 S100027_02963 S100027_02963 mccB mccB 2822077 2823219 - Cystathionine gamma-lyase Amino-acid biosynthesis%3B Cytoplasm%3B Lyase%3B Methionine biosynthesis%3B Pyridoxal phosphate%3B The enzymatic degradation of amino acids in cheese is believed to generate aroma compounds and therefore to be essential for flavor development. Cystathionine beta-lyase (CBL) can convert cystathionine to homocysteine but is also able to catalyze an alpha%2C gamma elimination. With methionine as a substrate%2C it produces volatile sulfur compounds which are important for flavor formation in Gouda cheese. Belongs to the trans-sulfuration enzymes family%3B KEGG: bli:BL02018 cystathionine gamma-lyase / homocysteine desulfhydrase gene gene2962 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02963 S100027_02964 S100027_02964 S100027_02964 2823221 2824144 - Cysteine synthase Amino-acid biosynthesis%3B Cysteine biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Belongs to the cysteine synthase/cystathionine beta- synthase family gene gene2963 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02964 S100027_02965 S100027_02965 mtnN mtnN 2824196 2824891 - Adenosylhomocysteine nucleosidase Amino-acid biosynthesis%3B Hydrolase%3B Menaquinone biosynthesis%3B Methionine biosynthesis%3B Catalyzes the direct conversion of aminodeoxyfutalosine (AFL) into dehypoxanthine futalosine (DHFL) and adenine via the hydrolysis of the N-glycosidic bon%3B this reaction seems to represent an essential step in the menaquinone biosynthesis pathway in Campylobacter species. Also catalyzes the hydrolysis of 5'-methylthioadenosine (MTA) to adenine and 5'-methylthioribose. Can also probably use S-adenosylhomocysteine (SAH) as substrate%2C leading to adenine and S-ribosylhomocysteine. These other activities highlight the tremendous versatility of the enzyme%2C which also plays key roles in S-adenosylmethionine recycling and in the biosynthesis of the quorum-sensing molecule autoinducer-2. Shows negligible activity with futalosine (FL) as substrate%3B Belongs to the PNP/UDP phosphorylase family%3B KEGG: pat:Patl_0518 adenosylhomocysteine nucleosidase gene gene2964 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02965 S100027_02966 S100027_02966 yrrT yrrT 2824913 2825554 - putative methyltransferase Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Could be a S-adenosyl-L-methionine-dependent methyltransferase%3B Belongs to the methyltransferase superfamily. YrrT family%3B KEGG: bsu:BSU27280 putative AdoMet-dependent methyltransferase%3B Methyltransferases gene gene2965 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02966 S100027_02967 S100027_02967 S100027_02967 2825744 2825947 + uncharacterized protein Coiled coil. gene gene2966 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02967 S100027_02968 S100027_02968 S100027_02968 2825986 2826678 - putative membrane protein YrrS Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2967 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02968 S100027_02969 S100027_02969 S100027_02969 2826737 2828491 - Penicillin-binding protein 4B Cell cycle%3B Cell division%3B Cell membrane%3B Membrane%3B Signal-anchor%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Penicillin-binding protein with an unknown catalytic activity. Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis. Beta-lactamase inactivates the PBPs by acylating an essential serine residue in the active site of these proteins%2C thereby interrupting normal cell wall synthesis. Belongs to the transpeptidase family gene gene2968 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02969 S100027_02970 S100027_02970 S100027_02970 2828546 2829022 - Transcription elongation factor GreA Coiled coil%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through%2C resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides%3B Belongs to the GreA/GreB family gene gene2969 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02970 S100027_02971 S100027_02971 S100027_02971 2829262 2829897 - Uridine kinase ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the uridine kinase family%3B KEGG: bli:BL02025 uridine kinase gene gene2970 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02971 S100027_02972 S100027_02972 S100027_02972 2829902 2831170 - putative protease YrrO Hydrolase%3B Protease%3B Belongs to the peptidase U32 family%3B KEGG: bli:BL02026 putative protease%3B Acting on peptide bonds (peptidases) gene gene2971 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02972 S100027_02973 S100027_02973 S100027_02973 2831185 2832114 - putative protease YrrN Hydrolase%3B Protease%3B Belongs to the peptidase U32 family%3B KEGG: bsu:BSU27350 putative protease%3B Acting on peptide bonds (peptidases) gene gene2972 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02973 S100027_02974 S100027_02974 S100027_02974 2832111 2832773 - Caffeoyl-CoA O-methyltransferase Metal-binding%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O- methyltransferase family%3B KEGG: ctc:CTC01062 caffeoyl-CoA O-methyltransferase gene gene2973 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02974 S100027_02975 S100027_02975 S100027_02975 2832921 2834033 - UPF0755 protein YrrL Belongs to the UPF0755 family gene gene2974 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02975 S100027_02976 S100027_02976 S100027_02976 2834228 2834512 - UPF0473 protein Belongs to the UPF0473 family gene gene2975 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02976 S100027_02977 S100027_02977 ruvX ruvX 2834523 2834942 - Putative pre-16S rRNA nuclease Cytoplasm%3B Hydrolase%3B Nuclease%3B Ribosome biogenesis%3B Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA%3B Belongs to the YqgF nuclease family%3B KEGG: dao:Desac_2916 putative holliday junction resolvase%3B Acting on ester bonds gene gene2976 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02977 S100027_02978 S100027_02978 S100027_02978 2834949 2835215 - UPF0297 protein Belongs to the UPF0297 family%3B KEGG: snu:SPNA45_01835 putative holliday junction resolvase%3B Acting on ester bonds gene gene2977 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02978 S100027_02979 S100027_02979 aarS aarS 2835299 2837935 - Alanine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B RNA-binding%3B tRNA-binding%3B Zinc%3B Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: dno:DNO_0286 alanyl-tRNA synthetase gene gene2978 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02979 S100027_02980 S100027_02980 S100027_02980 2838286 2839344 - UPF0118 membrane protein YrrI Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0118 (PerM) family gene gene2979 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02980 S100027_02981 S100027_02981 S100027_02981 2839582 2839773 - uncharacterized protein gene gene2980 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02981 S100027_02982 S100027_02982 S100027_02982 2839789 2840253 - uncharacterized protein gene gene2981 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02982 S100027_02983 S100027_02983 recD recD 2840342 2842738 - Exodeoxyribonuclease V ATP-binding%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs%2C requires at least 10 bases of 5'-ssDNA for helicase activity%3B Belongs to the RecD family. RecD-like subfamily%3B KEGG: bli:BL02037 exodeoxyribonuclease V alpha subunit gene gene2982 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02983 S100027_02984 S100027_02984 S100027_02984 2842789 2843439 - TPR repeat-containing protein YrrB Repeat%3B TPR repeat%3B Could be an interacting mediator in the complex formation among RNA sulfuration components%2C RNA processing components%2C and aminoacyl-tRNA synthetases. Contains 6 TPR repeats gene gene2983 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02984 S100027_02985 S100027_02985 mnmA mnmA 2843533 2844651 - tRNA-specific 2-thiouridylase MnmA ATP-binding%3B Cytoplasm%3B Disulfide bond%3B Nucleotide-binding%3B RNA-binding%3B Transferase%3B tRNA processing%3B tRNA-binding%3B Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA%2C leading to the formation of s(2)U34%3B Belongs to the MnmA/TRMU family%3B KEGG: azl:AZL_020120 tRNA-specific 2-thiouridylase%3B Sulfurtransferases gene gene2984 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02985 S100027_02986 S100027_02986 iscS iscS 2844757 2845896 - Cysteine desulfurase Iron%3B Iron-sulfur%3B Metal-binding%3B Pyridoxal phosphate%3B Transferase%3B Catalyzes the removal of elemental sulfur from cysteine to produce alanine%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily%3B KEGG: tti:THITH_16475 cysteine desulfurase gene gene2985 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02986 S100027_02987 S100027_02987 S100027_02987 2845917 2846333 - HTH-type transcriptional regulator CymR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Master repressor of cysteine metabolism in B. subtilis. Controls the expression of genes involved either in cysteine synthesis from sulfide (cysK)%2C sulfonates (ssu)%2C or methionine (mccAB) or in cystine uptake (tcyP). Activity of CymR is positively regulated by CysK in response to cysteine availability. When cysteine is present%2C the pool of O-acetylserine (OAS) is low%2C which leads to the formation of a CymR-CysK complex and transcriptional repression of the CymR regulon occurs. In the absence of cysteine%2C the OAS pool is high and the CymR-CysK complex is mostly dissociated%2C leading to a faster dissociation of CymR from its DNA targets and the lifting of CymR-dependent repression%3B Contains 1 HTH rrf2-type DNA-binding domain gene gene2986 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02987 S100027_02988 S100027_02988 S100027_02988 2846908 2848173 + putative AAA domain-containing protein YrvN ATP-binding%3B Nucleotide-binding%3B Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily gene gene2987 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02988 S100027_02989 S100027_02989 S100027_02989 2848258 2849022 - tRNA threonylcarbamoyladenosine dehydratase ATP-binding%3B Ligase%3B Nucleotide-binding%3B Catalyzes the ATP-dependent dehydration of threonylcarbamoyladenosine at position 37 (t(6)A37) to form cyclic t(6)A37 (ct(6)A37) in tRNAs that read codons beginning with adenine%3B Belongs to the HesA/MoeB/ThiF family gene gene2988 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02989 S100027_02990 S100027_02990 darS darS 2849442 2851220 - Aspartate--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn)%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: bsu:BSU27550 aspartyl-tRNA synthetase gene gene2989 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02990 S100027_02991 S100027_02991 harS harS 2851235 2852509 - Histidine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: bsu:BSU27560 histidyl-tRNA synthetase gene gene2990 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02991 S100027_02992 S100027_02992 S100027_02992 2852884 2853048 - uncharacterized protein gene gene2991 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02992 S100027_02993 S100027_02993 S100027_02993 2853191 2854762 + N-acetylmuramoyl-L-alanine amidase Cell wall%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Metal-binding%3B Secreted%3B Signal%3B Zinc%3B Probably involved in cell-wall metabolism%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B KEGG: bli:BL01120 N-acetylmuramoyl-L-alanine amidase gene gene2992 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02993 S100027_02994 S100027_02994 dtd1 dtd1 2854790 2855233 - D-aminoacyl-tRNA deacylase Cytoplasm%3B Hydrolase%3B D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules%2C this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo%3B Belongs to the DTD family%3B KEGG: sml:Smlt4166 D-tyrosyl-tRNA(Tyr) deacylase%3B Acting on ester bonds gene gene2993 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02994 S100027_02995 S100027_02995 relA relA 2855247 2857448 - GTP diphosphokinase ATP-binding%3B GTP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase%3B In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp (By similarity)%3B Belongs to the RelA/SpoT family%3B Contains 1 ACT domain%3B Contains 1 HD domain%3B KEGG: bsu:BSU27600 GTP pyrophosphokinase gene gene2994 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02995 S100027_02996 S100027_02996 aprT aprT 2857619 2858131 - Adenine phosphoribosyltransferase Cytoplasm%3B Glycosyltransferase%3B Purine salvage%3B Transferase%3B Catalyzes a salvage reaction resulting in the formation of AMP%2C that is energically less costly than de novo synthesis%3B Belongs to the purine/pyrimidine phosphoribosyltransferase family%3B KEGG: bli:BL01126 adenine phosphoribosyltransferase gene gene2995 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02996 S100027_02997 S100027_02997 recJ recJ 2858149 2860497 - Single-stranded-DNA-specific exonuclease RecJ Coiled coil%3B DNA-binding%3B Exonuclease%3B Hydrolase%3B Nuclease%3B Putative single-stranded-DNA-specific exonuclease (By similarity). RecA thread formation during DNA double-strand break repair requires RecJ or AadAB%3B Belongs to the RecJ family%3B Contains 1 OB DNA-binding domain%3B KEGG: bsu:BSU27620 single-stranded-DNA-specific exonuclease%3B Acting on ester bonds gene gene2996 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02997 S100027_02998 S100027_02998 S100027_02998 2860569 2860862 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2997 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02998 S100027_02999 S100027_02999 S100027_02999 2861016 2863241 - Protein translocase subunit SecDF Cell membrane%3B Membrane%3B Protein transport%3B Translocation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Required for efficient translocation of secretory pre- proteins under conditions of hypersecretion but is not required for the release of mature proteins from the membrane%3B Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)%3B In the N-terminal sectio%3B belongs to the SecD/SecF family. SecD subfamily%3B In the C-terminal sectio%3B belongs to the SecD/SecF family. SecF subfamily gene gene2998 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_02999 S100027_03000 S100027_03000 S100027_03000 2863278 2863574 - Post-transcriptional regulator ComN Competence%3B Cytoplasm%3B Required for post-transcription initiation control of the comE operon. Promotes the accumulation of its target comE mRNA to septal and polar sites gene gene2999 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03000 S100027_03001 S100027_03001 S100027_03001 2863692 2865245 + Stage V sporulation protein Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Involved%2C directly or indirectly%2C in spore cortex biosynthesis. Affects only indirectly the expression of late sporulation genes. Belongs to the polysaccharide synthase family gene gene3000 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03001 S100027_03002 S100027_03002 S100027_03002 2865254 2865904 - UPF0702 transmembrane protein YrbG Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0702 family gene gene3001 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03002 S100027_03003 S100027_03003 S100027_03003 2866060 2866443 + putative membrane protein YrzE Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3002 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03003 S100027_03004 S100027_03004 S100027_03004 2866625 2866885 - UPF0092 membrane protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0092 family gene gene3003 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03004 S100027_03005 S100027_03005 S100027_03005 2866935 2867822 - tRNA-guanine(34) transglycosylase Glycosyltransferase%3B Metal-binding%3B Queuosine biosynthesis%3B Transferase%3B tRNA processing%3B Zinc%3B Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp%2C -Asn%2C -His and -Tyr). After this exchange%2C a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine%2C resulting in the hypermodified nucleoside queuosine (Q) (7-(((4%2C5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)%3B Belongs to the queuine tRNA-ribosyltransferase family%3B KEGG: fau:Fraau_2350 queuine tRNA-ribosyltransferase%3B overlaps another CDS with the same product name gene gene3004 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03005 S100027_03006 S100027_03006 S100027_03006 2867819 2868079 - tRNA-guanine(34) transglycosylase Glycosyltransferase%3B Metal-binding%3B Queuosine biosynthesis%3B Transferase%3B tRNA processing%3B Zinc%3B Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp%2C -Asn%2C -His and -Tyr). After this exchange%2C a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine%2C resulting in the hypermodified nucleoside queuosine (Q) (7-(((4%2C5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)%3B Belongs to the queuine tRNA-ribosyltransferase family%3B KEGG: bsu:BSU27710 queuine tRNA-ribosyltransferase%3B overlaps another CDS with the same product name gene gene3005 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03006 S100027_03007 S100027_03007 queA queA 2868108 2869136 - S-adenosylmethionine:tRNA ribosyltransferase-isomerase Cytoplasm%3B Queuosine biosynthesis%3B S-adenosyl-L-methionine%3B Transferase%3B Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)%3B Belongs to the QueA family%3B KEGG: atu:Atu1678 S-adenosylmethionine:tRNA ribosyltransferase-isomerase gene gene3006 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03007 S100027_03008 S100027_03008 ruvB ruvB 2869177 2869377 - DNA helicase Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B KEGG: bamp:B938_12840 holliday junction DNA helicase RuvB%3B overlaps another CDS with the same product name gene gene3007 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03008 S100027_03009 S100027_03009 S100027_03009 2869370 2870374 - DNA helicase ATP-binding%3B DNA damage%3B DNA recombination%3B DNA repair%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B SOS response%3B RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing%3B Belongs to the RuvB family%3B KEGG: bsu:BSU27730 holliday junction DNA helicase RuvB%3B overlaps another CDS with the same product name gene gene3008 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03009 S100027_03010 S100027_03010 ruvA ruvA 2870384 2870989 - DNA helicase ATP-binding%3B DNA damage%3B DNA recombination%3B DNA repair%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B SOS response%3B RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates%2C in the presence of DNA%2C the weak ATPase activity of RuvB%3B Belongs to the RuvA family%3B KEGG: bsu:BSU27740 holliday junction DNA helicase RuvA gene gene3009 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03010 S100027_03011 S100027_03011 S100027_03011 2871112 2871633 - Protein BofC Signal%3B Sporulation. gene gene3010 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03011 S100027_03012 S100027_03012 S100027_03012 2871876 2872526 + Putative serine/threonine-protein kinase YrzF ATP-binding%3B Kinase%3B Nucleotide-binding%3B Serine/threonine-protein kinase%3B Transferase%3B Belongs to the protein kinase superfamily. Ser/Thr protein kinase family%3B Contains 1 protein kinase domain%3B KEGG: bcz:BCZK2452 null%3B Phosphotransferases with an alcohol group as acceptor gene gene3011 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03012 S100027_03013 S100027_03013 S100027_03013 2872597 2872719 + hypothetical protein gene gene3012 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03013 S100027_03014 S100027_03014 S100027_03014 2872804 2872983 - Small%2C acid-soluble spore protein Sporulation%3B Belongs to the SspH family gene gene3013 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03014 S100027_03015 S100027_03015 S100027_03015 2873079 2873543 - uncharacterized protein Metal-binding%3B Phosphoprotein%3B Belongs to the DinB family gene gene3014 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03015 S100027_03016 S100027_03016 S100027_03016 2873604 2874314 - UPF0714 protein YjqB Belongs to the UPF0714 family gene gene3015 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03016 S100027_03017 S100027_03017 S100027_03017 2874728 2874907 + uncharacterized protein gene gene3016 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03017 S100027_03018 S100027_03018 S100027_03018 2874999 2875325 - hypothetical protein gene gene3017 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03018 S100027_03019 S100027_03019 glgC glgC 2875467 2876189 - Glucose-1-phosphate adenylyltransferase Cytoplasm%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Belongs to the TACO1 family%3B KEGG: pmf:P9303_05381 glucose-1-phosphate adenylyltransferase gene gene3018 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03019 S100027_03020 S100027_03020 S100027_03020 2876306 2877736 - hypothetical protein gene gene3019 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03020 S100027_03021 S100027_03021 S100027_03021 2877862 2878497 - Sporulation cortex protein CoxA Signal%3B Sporulation. gene gene3020 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03021 S100027_03022 S100027_03022 S100027_03022 2878670 2879569 - SpoIVD-associated factor Sporulation%3B Probably involved in the assembly of some coat protein components implicated in both lysozyme resistance and germination. Could be required for the assembly of CotG. Associates with SpoIVD during the early stage of coat assembly. Contains 1 LysM repeat gene gene3021 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03022 S100027_03023 S100027_03023 nadA nadA 2879837 2880946 - Quinolinate synthase 4Fe-4S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Pyridine nucleotide biosynthesis%3B Transferase%3B Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate%3B Belongs to the quinolinate synthase A family. Type 3 subfamily%3B KEGG: bli:BL01153 quinolinate synthase gene gene3022 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03023 S100027_03024 S100027_03024 nadC nadC 2880968 2881807 - Nicotinate-nucleotide diphosphorylase (carboxylating) Alternative splicing%3B Chloroplast%3B Glycosyltransferase%3B Plastid%3B Pyridine nucleotide biosynthesis%3B Transferase%3B Transit peptide%3B Involved in the catabolism of quinolinic acid (QA)%3B Belongs to the NadC/ModD family%3B KEGG: bli:BL01154 nicotinate-nucleotide pyrophosphorylase (carboxylating) gene gene3023 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03024 S100027_03025 S100027_03025 nadB nadB 2881788 2883362 - L-aspartate oxidase Cytoplasm%3B FAD%3B Flavoprotein%3B Oxidoreductase%3B Pyridine nucleotide biosynthesis%3B Catalyzes the oxidation of L-aspartate to iminoaspartate. Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily%3B KEGG: bli:BL01155 L-aspartate oxidase gene gene3024 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03025 S100027_03026 S100027_03026 S100027_03026 2883463 2884641 + Cysteine desulfurase Iron%3B Iron-sulfur%3B Metal-binding%3B Pyridoxal phosphate%3B Transferase%3B Catalyzes the removal of elemental sulfur from cysteine to produce alanine (By similarity). Seems to be required for NAD biosynthesis (PubMed:8444804)%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily%3B KEGG: ppf:Pput_1517 cysteine desulfurase gene gene3025 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03026 S100027_03027 S100027_03027 S100027_03027 2884610 2885152 + Transcription repressor NadR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B In the presence of nicotinic acid represses transcription of the nadBCA and nifS-nadR operons. Also binds to DNA upstream of the niaP gene%2C probably regulating it as well. May bind nicotinic acid gene gene3026 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03027 S100027_03028 S100027_03028 S100027_03028 2885196 2886065 - Prephenate dehydratase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Lyase%3B Phenylalanine biosynthesis%3B Contains 1 ACT domain%3B Contains 1 prephenate dehydratase domain%3B KEGG: bld:BLi02917 prephenate dehydratase gene gene3027 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03028 S100027_03029 S100027_03029 pheB pheB 2886074 2886517 - Chorismate mutase Belongs to the UPF0735 family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU27910 chorismate mutase gene gene3028 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03029 S100027_03030 S100027_03030 S100027_03030 2886631 2887917 - GTPase Obg Cytoplasm%3B GTP-binding%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B An essential GTPase which binds GTP%2C GDP and possibly (p)ppGpp with moderate affinity%2C with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle%2C stress response%2C ribosome biogenesis and in those bacteria that undergo differentiation%2C in morphogenesis control%3B Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family%3B Contains 1 OBG-type G (guanine nucleotide-binding) domain gene gene3029 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03030 S100027_03031 S100027_03031 S100027_03031 2887950 2888528 - Sporulation initiation phosphotransferase Cytoplasm%3B Kinase%3B Phosphoprotein%3B Sensory transduction%3B Sporulation%3B Transferase%3B KEGG: bli:BL01158 stage 0 sporulation protein B (sporulation initiation phosphotransferase)%3B Transferring phosphorus-containing groups gene gene3030 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03031 S100027_03032 S100027_03032 S100027_03032 2888754 2889035 - 50S ribosomal protein L27 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L27P family gene gene3031 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03032 S100027_03033 S100027_03033 S100027_03033 2889048 2889389 - uncharacterized protein To M. genitalium MG233 gene gene3032 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03033 S100027_03034 S100027_03034 S100027_03034 2889402 2889710 - 50S ribosomal protein L21 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B This protein binds to 23S rRNA in the presence of protein L20%3B Belongs to the ribosomal protein L21P family gene gene3033 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03034 S100027_03035 S100027_03035 S100027_03035 2889867 2890733 - Stage IV sporulation protein FB Hydrolase%3B Membrane%3B Metal-binding%3B Metalloprotease%3B Protease%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Zinc%3B Implicated in the coupling of mother cell to forespore gene expression. Required for spore formation. Processes the pro- sigma K factor. Belongs to the peptidase M50B family%3B KEGG: bli:BL05293 stage IV sporulation protein FB%3B Metalloendopeptidases gene gene3034 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03035 S100027_03036 S100027_03036 S100027_03036 2890726 2891517 - Stage IV sporulation protein FA Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix. gene gene3035 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03036 S100027_03037 S100027_03037 S100027_03037 2891663 2892091 + uncharacterized protein Belongs to the AHA1 family gene gene3036 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03037 S100027_03038 S100027_03038 S100027_03038 2892091 2892411 + Transcriptional repressor SdpR Cytoplasm%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Represses the transcription of the sdpIR operon and of several other operons that probably contribute to delaying commitment to sporulation%3B Contains 1 HTH arsR-type DNA-binding domain gene gene3037 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03038 S100027_03039 S100027_03039 S100027_03039 2892456 2893262 - Septum site-determining protein MinD ATP-binding%3B Cell cycle%3B Cell division%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Septation%3B ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings (By similarity)%3B Belongs to the ParA family. MinD subfamily gene gene3038 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03039 S100027_03040 S100027_03040 S100027_03040 2893265 2893987 - putative septum site-determining protein MinC Cell cycle%3B Cell division%3B Septation%3B Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization%3B Belongs to the MinC family gene gene3039 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03040 S100027_03041 S100027_03041 S100027_03041 2894000 2894518 - Rod shape-determining protein MreD Cell membrane%3B Cell shape%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins (By similarity)%3B Belongs to the MreD family gene gene3040 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03041 S100027_03042 S100027_03042 S100027_03042 2894515 2895423 - Cell shape-determining protein MreC Cell shape%3B Coiled coil%3B Signal%3B Involved in formation and maintenance of cell shape%3B Belongs to the MreC family gene gene3041 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03042 S100027_03043 S100027_03043 S100027_03043 2895454 2896464 - Rod shape-determining protein MreB Cell shape%3B Involved in formation of the rod shape of the cell%3B Belongs to the FtsA/MreB family gene gene3042 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03043 S100027_03044 S100027_03044 S100027_03044 2896552 2896845 - UPF0758 protein Belongs to the UPF0758 family gene gene3043 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03044 S100027_03045 S100027_03045 S100027_03045 2897064 2897648 + hypothetical protein gene gene3044 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03045 S100027_03046 S100027_03046 S100027_03046 2897747 2898115 + SPBc2 prophage-derived uncharacterized protein YolD gene gene3045 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03046 S100027_03047 S100027_03047 S100027_03047 2898229 2898348 - hypothetical protein gene gene3046 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03047 S100027_03048 S100027_03048 rapI rapI 2898338 2899459 - Response regulator aspartate phosphatase Hydrolase%3B Protein phosphatase%3B Repeat%3B TPR repeat%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bli:BL02161 response regulator aspartate phosphatase I%3B Acting on ester bonds gene gene3047 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03048 S100027_03049 S100027_03049 S100027_03049 2899712 2901328 + putative ribonuclease YokI Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 449-571) inhibits growth upon expression in E. coli which is neutralized by cognate antitoxin YokJ%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene3048 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03049 S100027_03050 S100027_03050 S100027_03050 2901341 2901757 + hypothetical protein gene gene3049 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03050 S100027_03051 S100027_03051 S100027_03051 2901788 2902741 - Lysozyme M1 Disulfide bond%3B Glycosidase%3B Hydrolase%3B Secreted%3B Signal%3B This enzyme has both lysozyme (acetylmuramidase) and diacetylmuramidase activities. Belongs to the glycosyl hydrolase 25 family gene gene3050 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03051 S100027_03052 S100027_03052 S100027_03052 2902789 2903052 - SPBc2 prophage-derived protein BhlB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B May be involved in the secretion of the autolysin BlyA. Belongs to the SPP1 holin family gene gene3051 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03052 S100027_03053 S100027_03053 S100027_03053 2903068 2903361 - putative 11.0 kDa protein in cwlL 5'region To B. licheniformis xpaL1 and to B. subtilis XhlA gene gene3052 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03053 S100027_03054 S100027_03054 S100027_03054 2903401 2903583 - hypothetical protein gene gene3053 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03054 S100027_03055 S100027_03055 S100027_03055 2903580 2903903 - SPBc2 prophage-derived uncharacterized protein YomQ gene gene3054 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03055 S100027_03056 S100027_03056 S100027_03056 2903916 2905355 - Phage-like element PBSX protein XkdV To B. subtilis YqcC gene gene3055 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03056 S100027_03057 S100027_03057 S100027_03057 2905394 2906947 - hypothetical protein gene gene3056 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03057 S100027_03058 S100027_03058 S100027_03058 2906984 2908066 - hypothetical protein gene gene3057 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03058 S100027_03059 S100027_03059 S100027_03059 2908084 2908692 - N-acetylmuramoyl-L-alanine amidase Cell wall%3B Cell wall biogenesis/degradation%3B Glycosidase%3B Hydrolase%3B Magnesium%3B Secreted%3B Signal%3B Is the major glucosaminidase responsible for peptidoglycan structural determination during vegetative growth. Acts processively from the ends of the glycan strands. Also plays a role in motility%2C chemotaxis and cell division%3B Belongs to the glycosyl hydrolase 73 family%3B KEGG: smu:SMU_76 N-acetylmuramoyl-L-alanine amidase gene gene3058 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03059 S100027_03060 S100027_03060 S100027_03060 2908705 2909541 - hypothetical protein gene gene3059 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03060 S100027_03061 S100027_03061 S100027_03061 2909541 2910887 - hypothetical protein gene gene3060 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03061 S100027_03062 S100027_03062 S100027_03062 2910896 2911354 - hypothetical protein gene gene3061 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03062 S100027_03063 S100027_03063 S100027_03063 2911401 2913428 - Tape measure protein Host membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Viral tail assembly%3B Virus exit from host cell%3B Plays a role in virion tail formation. The length of the tape measure protein is proportional to the length of the phage's tail gene gene3062 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03063 S100027_03064 S100027_03064 S100027_03064 2913626 2913961 - hypothetical protein gene gene3063 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03064 S100027_03065 S100027_03065 S100027_03065 2914030 2914629 - hypothetical protein gene gene3064 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03065 S100027_03066 S100027_03066 S100027_03066 2915033 2915377 - hypothetical protein gene gene3065 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03066 S100027_03067 S100027_03067 S100027_03067 2915673 2916023 - hypothetical protein gene gene3066 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03067 S100027_03068 S100027_03068 S100027_03068 2916039 2916488 - Collagen alpha-1(V) chain Collagen%3B Extracellular matrix%3B Heparin-binding%3B Hydroxylation%3B Repeat%3B Secreted%3B Signal%3B Sulfation%3B Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA%2C heparan sulfate%2C thrombospondin%2C heparin%2C and insulin (By similarity)%3B Belongs to the fibrillar collagen family%3B Contains 1 fibrillar collagen NC1 domain%3B Contains 1 laminin G-like domain gene gene3067 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03068 S100027_03069 S100027_03069 S100027_03069 2916514 2917830 - hypothetical protein gene gene3068 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03069 S100027_03070 S100027_03070 S100027_03070 2917871 2918500 - hypothetical protein gene gene3069 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03070 S100027_03071 S100027_03071 S100027_03071 2918490 2919734 - hypothetical protein gene gene3070 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03071 S100027_03072 S100027_03072 S100027_03072 2919740 2919910 - hypothetical protein gene gene3071 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03072 S100027_03073 S100027_03073 S100027_03073 2919922 2921631 - uncharacterized protein Belongs to the phage terminase family gene gene3072 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03073 S100027_03074 S100027_03074 S100027_03074 2921631 2922164 - hypothetical protein gene gene3073 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03074 S100027_03075 S100027_03075 S100027_03075 2922251 2922577 - hypothetical protein gene gene3074 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03075 S100027_03076 S100027_03076 S100027_03076 2922546 2922920 - hypothetical protein gene gene3075 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03076 S100027_03077 S100027_03077 S100027_03077 2923080 2923724 - hypothetical protein gene gene3076 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03077 S100027_03078 S100027_03078 S100027_03078 2923943 2924167 - Spore coat protein Sporulation. gene gene3077 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03078 S100027_03079 S100027_03079 S100027_03079 2924917 2925297 - hypothetical protein gene gene3078 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03079 S100027_03080 S100027_03080 S100027_03080 2925315 2925413 - hypothetical protein gene gene3079 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03080 S100027_03081 S100027_03081 S100027_03081 2925410 2925787 - hypothetical protein gene gene3080 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03081 S100027_03082 S100027_03082 S100027_03082 2925803 2926318 - hypothetical protein gene gene3081 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03082 S100027_03083 S100027_03083 S100027_03083 2926322 2926492 - hypothetical protein gene gene3082 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03083 S100027_03084 S100027_03084 S100027_03084 2926489 2927028 - hypothetical protein gene gene3083 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03084 S100027_03085 S100027_03085 S100027_03085 2927025 2927480 - hypothetical protein gene gene3084 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03085 S100027_03086 S100027_03086 S100027_03086 2927440 2927895 - hypothetical protein gene gene3085 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03086 S100027_03087 S100027_03087 S100027_03087 2928032 2930464 - Putative helicase L207/L206 ATP-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Contains 1 SF3 helicase domain gene gene3086 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03087 S100027_03088 S100027_03088 S100027_03088 2930525 2930965 - hypothetical protein gene gene3087 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03088 S100027_03089 S100027_03089 S100027_03089 2930984 2931337 - hypothetical protein gene gene3088 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03089 S100027_03090 S100027_03090 S100027_03090 2931327 2932262 - hypothetical protein gene gene3089 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03090 S100027_03091 S100027_03091 S100027_03091 2932266 2932823 - hypothetical protein gene gene3090 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03091 S100027_03092 S100027_03092 S100027_03092 2932916 2933020 - hypothetical protein gene gene3091 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03092 S100027_03093 S100027_03093 S100027_03093 2933017 2933286 - hypothetical protein gene gene3092 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03093 S100027_03094 S100027_03094 S100027_03094 2933283 2933474 - hypothetical protein gene gene3093 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03094 S100027_03095 S100027_03095 S100027_03095 2933490 2933624 - hypothetical protein gene gene3094 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03095 S100027_03096 S100027_03096 S100027_03096 2933625 2933864 - ImmF control region 10 kDa protein DNA-binding%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene3095 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03096 S100027_03097 S100027_03097 S100027_03097 2934114 2934557 + Repressor LexA DNA-binding%3B Early protein%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH cro/C1-type DNA-binding domain%3B KEGG: cpas:Clopa_0551 repressor LexA gene gene3096 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03097 S100027_03098 S100027_03098 S100027_03098 2934661 2935068 + putative immunity region protein gene gene3097 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03098 S100027_03099 S100027_03099 S100027_03099 2935108 2936496 + putative immunity region protein DNA integration%3B DNA invertase%3B DNA recombination%3B DNA-binding%3B Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene3098 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03099 S100027_03100 S100027_03100 S100027_03100 2936509 2936895 - UPF0758 protein Belongs to the UPF0758 family gene gene3099 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03100 S100027_03101 S100027_03101 S100027_03101 2936950 2937522 - Septum formation protein Maf Cytoplasm%3B Involved in septum formation%3B Belongs to the maf family gene gene3100 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03101 S100027_03102 S100027_03102 S100027_03102 2937676 2938707 - Stage II sporulation protein Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Involved in endospore development. Contains 1 SPOR domain gene gene3101 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03102 S100027_03103 S100027_03103 comC comC 2938911 2939660 - Type 4 prepilin-like protein leader peptide-processing enzyme Cell membrane%3B Competence%3B Hydrolase%3B Membrane%3B Methyltransferase%3B Multifunctional enzyme%3B Protease%3B S-adenosyl-L-methionine%3B Sporulation%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue%3B Belongs to the peptidase A24 family%3B KEGG: bli:BL00633 leader peptidase (prepilin peptidase) / N-methyltransferase%3B Prepilin peptidase gene gene3102 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03103 S100027_03104 S100027_03104 folC folC 2939803 2941107 - Dihydrofolate synthase ATP-binding%3B Folate biosynthesis%3B Ligase%3B Magnesium%3B Metal-binding%3B Multifunctional enzyme%3B Nucleotide-binding%3B Transferase%3B Can complement an H. volcanii mutant strain that is thymidine auxotroph because it lacks the two dihydrofolate reductase genes encoded by hdrA and hdrB%3B In the N-terminal sectio%3B belongs to the folylpolyglutamate synthase family%3B In the C-terminal sectio%3B belongs to the DHPS family%3B Contains 1 pterin-binding domain%3B KEGG: bld:BLi02937 dihydrofolate synthase / folylpolyglutamate synthase gene gene3103 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03104 S100027_03105 S100027_03105 varS varS 2941183 2943675 - Valine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Ligase%3B Mitochondrion%3B Nucleotide-binding%3B Protein biosynthesis%3B Transit peptide%3B Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: rip:RIEPE_0265 valyl-tRNA synthetase%3B overlaps another CDS with the same product name gene gene3104 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03105 S100027_03106 S100027_03106 S100027_03106 2943672 2943824 - Valine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Coiled coil%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine%2C to avoid such errors%2C it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner%3B Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily%3B KEGG: bli:BL00631 valyl-tRNA synthetase%3B overlaps another CDS with the same product name gene gene3105 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03106 S100027_03107 S100027_03107 S100027_03107 2944286 2944477 + putative membrane protein YszA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3106 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03107 S100027_03108 S100027_03108 S100027_03108 2944497 2945519 - uncharacterized protein gene gene3107 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03108 S100027_03109 S100027_03109 S100027_03109 2945547 2947004 - Stage VI sporulation protein D Sporulation. gene gene3108 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03109 S100027_03110 S100027_03110 S100027_03110 2947153 2948448 - Glutamate-1-semialdehyde 2%2C1-aminomutase Cytoplasm%3B Isomerase%3B Porphyrin biosynthesis%3B Pyridoxal phosphate%3B Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily%3B KEGG: bsu:BSU28120 glutamate-1-semialdehyde 2%2C1-aminomutase gene gene3109 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03110 S100027_03111 S100027_03111 hemB hemB 2948474 2949448 - Porphobilinogen synthase Heme biosynthesis%3B Lyase%3B Magnesium%3B Metal-binding%3B Porphyrin biosynthesis%3B Zinc%3B Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit%2C each at a distinct site%2C and catalyzes their condensation to form porphobilinogen (By similarity)%3B Belongs to the ALAD family%3B KEGG: bli:BL00627 porphobilinogen synthase gene gene3110 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03111 S100027_03112 S100027_03112 S100027_03112 2949452 2950243 - Uroporphyrinogen-III synthase Lyase%3B Methyltransferase%3B Multifunctional enzyme%3B Porphyrin biosynthesis%3B S-adenosyl-L-methionine%3B Transferase%3B May catalyze sequential reactions to synthesize uroporphyrinogen III from hydroxymethylbilane (HMB) and then precorrin-2%2C which are intermediate compounds in both vitamin B12 and siroheme biosyntheses%3B In the N-terminal sectio%3B belongs to the precorrin methyltransferase family%3B In the C-terminal sectio%3B belongs to the uroporphyrinogen-III synthase family%3B KEGG: bli:BL00626 uroporphyrinogen-III synthase gene gene3111 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03112 S100027_03113 S100027_03113 hemC hemC 2950233 2951174 - Hydroxymethylbilane synthase Porphyrin biosynthesis%3B Transferase%3B Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps%3B Belongs to the HMBS family%3B KEGG: bli:BL00625 hydroxymethylbilane synthase gene gene3112 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03113 S100027_03114 S100027_03114 S100027_03114 2951214 2952044 - Protein HemX Cell membrane%3B Membrane%3B Porphyrin biosynthesis%3B Transmembrane%3B Transmembrane helix%3B Required for HemL synthesis. To M. leprae U1620K gene gene3113 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03114 S100027_03115 S100027_03115 hemA hemA 2952050 2953435 - Glutamyl-tRNA reductase NADP%3B Oxidoreductase%3B Porphyrin biosynthesis%3B Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)%3B Belongs to the glutamyl-tRNA reductase family%3B KEGG: bay:RBAM_025230 glutamyl-tRNA reductase gene gene3114 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03115 S100027_03116 S100027_03116 S100027_03116 2953600 2954085 + putative membrane protein YsxD Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3115 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03116 S100027_03117 S100027_03117 S100027_03117 2954134 2954721 - putative GTP-binding protein EngB Cell cycle%3B Cell division%3B GTP-binding%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Septation%3B Necessary for normal cell division and for the maintenance of normal septation%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. EngB GTPase family%3B Contains 1 EngB-type G (guanine nucleotide-binding) domain gene gene3116 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03117 S100027_03118 S100027_03118 S100027_03118 2954718 2954999 - Endopeptidase La ATP-binding%3B Cytoplasm%3B Hydrolase%3B Nucleotide-binding%3B Protease%3B Serine protease%3B Stress response%3B ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Binds to DNA in a double-stranded%2C site-specific manner (By similarity). Has been implicated in preventing sigma(G) activity under non-sporulation conditions%3B Belongs to the peptidase S16 family%3B Contains 1 Lon domain%3B KEGG: mmk:MU9_3240 ATP-dependent Lon protease%3B overlaps another CDS with the same product name gene gene3117 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03118 S100027_03119 S100027_03119 S100027_03119 2954972 2957041 - Endopeptidase La ATP-binding%3B Cytoplasm%3B Hydrolase%3B Nucleotide-binding%3B Protease%3B Serine protease%3B Stress response%3B ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Binds to DNA in a double-stranded%2C site-specific manner%3B Belongs to the peptidase S16 family%3B Contains 1 Lon domain%3B KEGG: bli:BL00621 ATP-dependent Lon protease%3B overlaps another CDS with the same product name gene gene3118 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03119 S100027_03120 S100027_03120 lonB lonB 2957260 2958915 - Lon protease ATP-binding%3B Cytoplasm%3B Hydrolase%3B Nucleotide-binding%3B Protease%3B Serine protease%3B Stress response%3B ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Binds to DNA in a double-stranded%2C site-specific manner (By similarity)%3B Belongs to the peptidase S16 family%3B KEGG: bli:BL00620 Lon-like ATP-dependent protease%3B Serine endopeptidases gene gene3119 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03120 S100027_03121 S100027_03121 S100027_03121 2959098 2960363 - ATP-dependent Clp protease ATP-binding subunit ClpX ATP-binding%3B Chaperone%3B Metal-binding%3B Nucleotide-binding%3B Zinc%3B Zinc-finger%3B ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP%3B Belongs to the ClpX chaperone family gene gene3120 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03121 S100027_03122 S100027_03122 S100027_03122 2960632 2961906 - Trigger factor Cell cycle%3B Cell division%3B Chaperone%3B Cytoplasm%3B Isomerase%3B Rotamase%3B Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase%3B Belongs to the FKBP-type PPIase family. Tig subfamily%3B Contains 1 PPIase FKBP-type domain gene gene3121 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03122 S100027_03123 S100027_03123 S100027_03123 2962133 2963140 - TPR repeat-containing protein YsoA Repeat%3B TPR repeat%3B Contains 3 TPR repeats gene gene3122 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03123 S100027_03124 S100027_03124 leuD leuD 2963270 2963869 - 3-isopropylmalate dehydratase Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Leucine biosynthesis%3B Lyase%3B Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate%2C via the formation of 2-isopropylmaleate%3B Belongs to the LeuD family. LeuD type 1 subfamily%3B KEGG: bli:BL00615 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit gene gene3123 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03124 S100027_03125 S100027_03125 leuC leuC 2963882 2965300 - 3-isopropylmalate dehydratase 4Fe-4S%3B Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Iron%3B Iron-sulfur%3B Leucine biosynthesis%3B Lyase%3B Metal-binding%3B Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate%2C via the formation of 2-isopropylmaleate%3B Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily%3B KEGG: bsu:BSU28260 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit gene gene3124 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03125 S100027_03126 S100027_03126 leuB leuB 2965334 2966446 - 3-isopropylmalate dehydrogenase Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Cytoplasm%3B Leucine biosynthesis%3B Magnesium%3B Manganese%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate%3B Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily%3B KEGG: xft:PD1397 3-isopropylmalate dehydrogenase gene gene3125 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03126 S100027_03127 S100027_03127 leuA leuA 2966474 2968030 - 2-isopropylmalate synthase Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Leucine biosynthesis%3B Transferase%3B Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)%3B Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily%3B KEGG: dgg:DGI_2503 2-isopropylmalate synthase gene gene3126 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03127 S100027_03128 S100027_03128 ilvC ilvC 2968017 2969045 - Ketol-acid reductoisomerase (NADP(+)) Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B NADP%3B Oxidoreductase%3B Belongs to the ketol-acid reductoisomerase family%3B KEGG: bsu:BSU28290 ketol-acid reductoisomerase gene gene3127 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03128 S100027_03129 S100027_03129 ilvH ilvH 2969069 2969587 - Acetolactate synthase Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Transferase%3B Belongs to the acetolactate synthase small subunit family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU28300 acetolactate synthase I/III small subunit%3B overlaps another CDS with the same product name gene gene3128 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03129 S100027_03130 S100027_03130 ilvB ilvB 2969584 2971308 - Acetolactate synthase Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B FAD%3B Flavoprotein%3B Magnesium%3B Metal-binding%3B Thiamine pyrophosphate%3B Transferase%3B Belongs to the TPP enzyme family%3B KEGG: bsu:BSU28310 acetolactate synthase I/II/III large subunit%3B overlaps another CDS with the same product name gene gene3129 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03130 S100027_03131 S100027_03131 S100027_03131 2971733 2972647 - Branched-chain-amino-acid transaminase Aminotransferase%3B Pyridoxal phosphate%3B Transferase%3B Acts on the D-isomers of alanine%2C leucine%2C aspartate%2C glutamate%2C aminobutyrate%2C norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction. The second half-reaction is the reverse of the first%2C transferring the amino group from the pyridoxamine to a second alpha-keto acid to form the product D- amino acid via a ping-pong mechanism. This is an important process in the formation of D-alanine and D-glutamate%2C which are essential bacterial cell wall components (By similarity)%3B Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bli:BL00607 branched-chain amino acid aminotransferase gene gene3130 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03131 S100027_03132 S100027_03132 S100027_03132 2973101 2973331 + hypothetical protein gene gene3131 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03132 S100027_03133 S100027_03133 gdhA gdhA 2973374 2974756 - Glutamate dehydrogenase (NADP(+)) NADP%3B Oxidoreductase%3B Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia%3B Belongs to the Glu/Leu/Phe/Val dehydrogenases family%3B KEGG: bli:BL00756 glutamate dehydrogenase (NADP+) gene gene3132 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03133 S100027_03134 S100027_03134 S100027_03134 2975169 2975423 + hypothetical protein gene gene3133 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03134 S100027_03135 S100027_03135 S100027_03135 2975467 2975958 - PERQ amino acid-rich with GYF domain-containing protein May play a role in tyrosine kinase receptor signaling regulation%3B Belongs to the PERQ family%3B Contains 1 GYF domain gene gene3134 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03135 S100027_03136 S100027_03136 S100027_03136 2976394 2976609 - Phage-like element PBSX protein XkdE Belongs to the phage portal family. PBSX subfamily gene gene3135 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03136 S100027_03137 S100027_03137 S100027_03137 2976613 2977908 - PBSX phage terminase large subunit Viral genome packaging%3B Virus exit from host cell%3B Functions as a terminase. To B. subtilis YqaT and phage SPP1 terminase large subunit gene gene3136 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03137 S100027_03138 S100027_03138 S100027_03138 2977905 2978765 - hypothetical protein gene gene3137 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03138 S100027_03139 S100027_03139 S100027_03139 2978812 2979060 - hypothetical protein gene gene3138 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03139 S100027_03140 S100027_03140 S100027_03140 2979188 2980213 - DNA (cytosine-5-)-methyltransferase Methyltransferase%3B Restriction system%3B S-adenosyl-L-methionine%3B Transferase%3B This methylase recognizes the double-stranded sequence GTGCAC%2C causes specific methylation on C-? on both strands%2C and protects the DNA from cleavage by the ApaLI endonuclease. Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family%3B Contains 1 SAM-dependent MTase C5-type domain%3B KEGG: bld:BLi02974 DNA (cytosine-5)-methyltransferase 1 gene gene3139 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03140 S100027_03141 S100027_03141 S100027_03141 2980362 2980553 - hypothetical protein gene gene3140 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03141 S100027_03142 S100027_03142 S100027_03142 2980584 2980871 - hypothetical protein gene gene3141 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03142 S100027_03143 S100027_03143 S100027_03143 2980966 2981445 - putative antitoxin YezG Coiled coil%3B Probable antitoxin component of a toxin-antitoxin (TA) module. Probably neutralizes the ability to inhibit growth of cognate toxin YeeF. Probably does not have antitoxin activity on other toxins with the LXG toxin domain (Probable) gene gene3142 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03143 S100027_03144 S100027_03144 S100027_03144 2981451 2983445 - Ribonuclease YxiD Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene3143 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03144 S100027_03145 S100027_03145 S100027_03145 2983639 2984829 + Response regulator aspartate phosphatase Hydrolase%3B Protein phosphatase%3B Repeat%3B TPR repeat%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bpu:BPUM_3641 response regulator aspartate phosphatase K%3B Acting on ester bonds gene gene3144 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03145 S100027_03146 S100027_03146 S100027_03146 2984826 2984957 + hypothetical protein gene gene3145 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03146 S100027_03147 S100027_03147 S100027_03147 2985052 2985300 - hypothetical protein gene gene3146 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03147 S100027_03148 S100027_03148 S100027_03148 2985549 2985698 - hypothetical protein gene gene3147 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03148 S100027_03149 S100027_03149 S100027_03149 2985826 2985902 - tRNA-Arg tRNA gene3148 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03149 S100027_03150 S100027_03150 S100027_03150 2986022 2986543 - Putative metallophosphoesterase YsnB Hydrolase%3B Belongs to the metallophosphoesterase superfamily. YfcE family gene gene3149 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03150 S100027_03151 S100027_03151 rdgB rdgB 2986560 2987150 - XTP/dITP diphosphatase Hydrolase%3B Magnesium%3B Manganese%3B Metal-binding%3B Nucleotide metabolism%3B Nucleotide-binding%3B Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP/dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool%2C thus preventing their incorporation into DNA and avoiding chromosomal lesions%3B Belongs to the HAM1 NTPase family%3B KEGG: gme:Gmet_1875 XTP/dITP diphosphohydrolase gene gene3150 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03151 S100027_03152 S100027_03152 S100027_03152 2987172 2987912 - tRNA nucleotidyltransferase Nucleotidyltransferase%3B Transferase%3B tRNA processing%3B Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates%3B Belongs to the RNase PH family%3B KEGG: bli:BL00312 ribonuclease PH gene gene3151 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03152 S100027_03153 S100027_03153 S100027_03153 2988038 2989147 - Spore germination protein GerM Germination%3B Sporulation. gene gene3152 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03153 S100027_03154 S100027_03154 murI murI 2989299 2990114 - Glutamate racemase Cell shape%3B Cell wall biogenesis/degradation%3B Isomerase%3B Peptidoglycan synthesis%3B Provides the (R)-glutamate required for cell wall biosynthesis%3B Belongs to the aspartate/glutamate racemases family%3B KEGG: bsu:BSU28390 glutamate racemase gene gene3153 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03154 S100027_03155 S100027_03155 S100027_03155 2990125 2990568 - putative HTH-type transcriptional regulator YsmB DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH marR-type DNA-binding domain gene gene3154 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03155 S100027_03156 S100027_03156 S100027_03156 2990732 2990956 - Spore germination protein GerE DNA-binding%3B Germination%3B Transcription%3B Transcription regulation%3B Involved in the regulation of spore formation. Directs the transcription of several genes that encode structural components of the protein coat that encases the mature spore (CotB%2C CotC%2C CotG%2C CotS%2C CotV%2C CotW%2C CotX%2C CotY and CotZ). Controls also the cgeAB and cgeCDE operons. Contains 1 HTH luxR-type DNA-binding domain gene gene3155 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03156 S100027_03157 S100027_03157 S100027_03157 2991132 2991830 - putative oxidoreductase Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family gene gene3156 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03157 S100027_03158 S100027_03158 S100027_03158 2991848 2992318 - uncharacterized protein KEGG: bli:BL00319 acyl-CoA thioester hydrolase%3B Thiolester hydrolases gene gene3157 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03158 S100027_03159 S100027_03159 sdhB sdhB 2992381 2993145 - Succinate dehydrogenase (quinone) 2Fe-2S%3B 3Fe-4S%3B 4Fe-4S%3B Electron transport%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase%3B Transport%3B Tricarboxylic acid cycle%3B Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family%3B Contains 1 4Fe-4S ferredoxin-type domain%3B KEGG: bsu:BSU28430 succinate dehydrogenase / fumarate reductase%2C iron-sulfur subunit%3B overlaps another CDS with the same product name gene gene3158 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03159 S100027_03160 S100027_03160 sdhA sdhA 2993142 2994905 - Succinate dehydrogenase (quinone) Cell membrane%3B Electron transport%3B FAD%3B Flavoprotein%3B Membrane%3B Oxidoreductase%3B Transport%3B Tricarboxylic acid cycle%3B Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily%3B KEGG: bsu:BSU28440 succinate dehydrogenase / fumarate reductase%2C flavoprotein subunit%3B overlaps another CDS with the same product name gene gene3159 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03160 S100027_03161 S100027_03161 S100027_03161 2994939 2995547 - Succinate dehydrogenase cytochrome b558 subunit Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Tricarboxylic acid cycle%3B Di-heme cytochrome of the succinate dehydrogenase complex. Belongs to the cytochrome b558 family gene gene3160 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03161 S100027_03162 S100027_03162 S100027_03162 2995849 2996292 + uncharacterized protein gene gene3161 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03162 S100027_03163 S100027_03163 S100027_03163 2996337 2997566 - Aspartate kinase Alternative initiation%3B Amino-acid biosynthesis%3B ATP-binding%3B Diaminopimelate biosynthesis%3B Kinase%3B Lysine biosynthesis%3B Nucleotide-binding%3B Repeat%3B Transferase%3B Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate%2C which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine%2C isoleucine and methionine%3B Belongs to the aspartokinase family%3B Contains 2 ACT domains%3B KEGG: vsp:VS_2582 aspartate kinase gene gene3162 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03163 S100027_03164 S100027_03164 S100027_03164 2997960 2999732 - UvrABC system protein Cytoplasm%3B DNA damage%3B DNA excision%3B DNA repair%3B Excision nuclease%3B SOS response%3B The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision%3B Belongs to the UvrC family%3B Contains 1 GIY-YIG domain%3B Contains 1 UVR domain gene gene3163 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03164 S100027_03165 S100027_03165 S100027_03165 2999875 3000189 - Thioredoxin Disulfide bond%3B Electron transport%3B Redox-active center%3B Transport%3B Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Belongs to the thioredoxin family%3B Contains 1 thioredoxin domain gene gene3164 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03165 S100027_03166 S100027_03166 S100027_03166 3000402 3001379 - Electron transfer flavoprotein subunit alpha Electron transport%3B FAD%3B Flavoprotein%3B Transport%3B The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity)%3B Belongs to the ETF alpha-subunit/FixB family gene gene3165 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03166 S100027_03167 S100027_03167 S100027_03167 3001429 3002202 - Electron transfer flavoprotein subunit beta Electron transport%3B FAD%3B Flavoprotein%3B Transport%3B The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity)%3B Belongs to the ETF beta-subunit/FixA family gene gene3166 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03167 S100027_03168 S100027_03168 S100027_03168 3002234 3003010 - Enoyl-CoA hydratase Fatty acid metabolism%3B Lipid degradation%3B Lipid metabolism%3B Lyase%3B Involved in the degradation of long-chain fatty acids. Belongs to the enoyl-CoA hydratase/isomerase family%3B KEGG: bsu:BSU28540 enoyl-CoA hydratase gene gene3167 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03168 S100027_03169 S100027_03169 S100027_03169 3003013 3003615 - Fatty acid metabolism regulator protein Cytoplasm%3B DNA-binding%3B Fatty acid metabolism%3B Lipid degradation%3B Lipid metabolism%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation%2C including acdA%2C fadA%2C fadB%2C fadE%2C fadF%2C fadG%2C fadH%2C fadM%2C fadN%2C lcfA and lcfB. Binding of FadR to DNA is specifically inhibited by long chain fatty acyl-CoA compounds of 14-20 carbon atoms in length%3B Contains 1 HTH tetR-type DNA-binding domain gene gene3168 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03169 S100027_03170 S100027_03170 S100027_03170 3003757 3005436 - Long-chain-fatty-acid--CoA ligase ATP-binding%3B Fatty acid metabolism%3B Ligase%3B Lipid metabolism%3B Nucleotide-binding%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: care:LT85_4544 long-chain acyl-CoA synthetase gene gene3169 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03170 S100027_03171 S100027_03171 S100027_03171 3005646 3006050 - UPF0719 transmembrane protein YshE Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0719 family gene gene3170 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03171 S100027_03172 S100027_03172 S100027_03172 3006069 3008426 - Endonuclease MutS2 ATP-binding%3B DNA-binding%3B Endonuclease%3B Hydrolase%3B Nuclease%3B Nucleotide-binding%3B Belongs to the DNA mismatch repair MutS family. MutS2 subfamily%3B Contains 1 Smr domain gene gene3171 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03172 S100027_03173 S100027_03173 S100027_03173 3008443 3010158 - DNA polymerase/3'-5' exonuclease PolX DNA damage%3B DNA repair%3B DNA replication%3B DNA synthesis%3B DNA-binding%3B DNA-directed DNA polymerase%3B Hydrolase%3B Magnesium%3B Manganese%3B Metal-binding%3B Multifunctional enzyme%3B Nucleotidyltransferase%3B Transferase%3B Strictly DNA-template-directed DNA polymerase%2C preferentially acting on DNA structures containing gaps from one to a few nucleotides and bearing a phosphate group at the 5' end of the downstream DNA. The fact that PolX is able to conduct filling of a single-nucleotide gap%2C allowing further sealing of the resulting nick by a DNA ligase%2C points to a putative role in base excision repair (BER) during the B. subtilis life cycle. Moreover%2C also possesses a 3'-5' exonuclease activity able to edit unpaired 3'-termini in a gapped DNA substrate and likely involved in resecting unannealed 3'-termini during DNA repair. The same PolX molecule could perform the subsequent gap-filling step. Does not display 5'-deoxyribose 5'-phosphate (dRP) lyase activity%2C as predicted by the lack of the lysine and tyrosine residues responsible for the dRP lyase activity in some other PolX members%3B In the N-terminal sectio%3B belongs to the DNA polymerase type-X family%3B In the C-terminal sectio%3B belongs to the PHP family gene gene3172 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03173 S100027_03174 S100027_03174 S100027_03174 3010302 3010838 - putative transmembrane protein YshB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3173 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03174 S100027_03175 S100027_03175 S100027_03175 3010847 3011104 - Cell division protein ZapA Cell cycle%3B Cell division%3B Coiled coil%3B Cytoplasm%3B Septation%3B Activator of cell division through the inhibition of FtsZ GTPase activity%2C therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division%3B Belongs to the ZapA family. Type 2 subfamily gene gene3174 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03175 S100027_03176 S100027_03176 rnhC rnhC 3011254 3012195 + Ribonuclease H Cytoplasm%3B Endonuclease%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nuclease%3B Endonuclease that specifically degrades the RNA of RNA- DNA hybrids%3B Belongs to the RNase HII family. RnhC subfamily%3B KEGG: bsu:BSU28620 ribonuclease HIII gene gene3175 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03176 S100027_03177 S100027_03177 S100027_03177 3012943 3013746 + hypothetical protein gene gene3176 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03177 S100027_03178 S100027_03178 S100027_03178 3013824 3014684 - putative transposase-like protein DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene3177 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03178 S100027_03179 S100027_03179 S100027_03179 3014654 3014986 - hypothetical protein gene gene3178 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03179 S100027_03180 S100027_03180 S100027_03180 3015485 3015784 + hypothetical protein gene gene3179 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03180 S100027_03181 S100027_03181 S100027_03181 3015856 3017298 + hypothetical protein gene gene3180 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03181 S100027_03182 S100027_03182 phnC phnC 3017307 3017999 + Phosphonate-transporting ATPase ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the ABC transporter superfamily. Energy- coupling factor EcfA family%3B Contains 1 ABC transporter domain%3B KEGG: maq:Maqu_3258 phosphonate transport system ATP-binding protein gene gene3181 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03182 S100027_03183 S100027_03183 S100027_03183 3017956 3018492 + hypothetical protein gene gene3182 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03183 S100027_03184 S100027_03184 S100027_03184 3018503 3019051 + hypothetical protein gene gene3183 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03184 S100027_03185 S100027_03185 pheT pheT 3019223 3021637 - Phenylalanine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B RNA-binding%3B tRNA-binding%3B Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily%3B Contains 1 B5 domain%3B Contains 1 FDX-ACB domain%3B Contains 1 tRNA-binding domain%3B KEGG: bsu:BSU28630 phenylalanyl-tRNA synthetase beta chain gene gene3184 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03185 S100027_03186 S100027_03186 pheS pheS 3021653 3022687 - Phenylalanine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily%3B KEGG: nmp:NMBB_0820 phenylalanyl-tRNA synthetase alpha chain gene gene3185 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03186 S100027_03187 S100027_03187 S100027_03187 3023049 3023795 - putative tRNA/rRNA methyltransferase YsgA Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family gene gene3186 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03187 S100027_03188 S100027_03188 S100027_03188 3023910 3024125 + Small%2C acid-soluble spore protein Sporulation%3B Belongs to the SspI family gene gene3187 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03188 S100027_03189 S100027_03189 S100027_03189 3024157 3025953 - Carbon starvation protein A like protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the CstA family gene gene3188 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03189 S100027_03190 S100027_03190 S100027_03190 3026157 3026432 - hypothetical protein gene gene3189 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03190 S100027_03191 S100027_03191 abfA abfA 3026526 3028034 - Non-reducing end alpha-L-arabinofuranosidase Carbohydrate metabolism%3B Cytoplasm%3B Glycosidase%3B Hydrolase%3B Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the cleavage of terminal alpha-(1->5)-arabinofuranosyl bonds in small oligosaccharides as alpha-(1->5)-linked arabinobiose/arabinotriose%2C but does not display significant activity against linear non-substituted arabinan. It is also highly efficient in the cleavage of alpha-(1->3)-linked arabinoside of xylobiose and of the alpha-(1->3)-linked arabinoside decorations of polymeric wheat arabinoxylan. It exhibits very low activity against sugar beet arabinan%3B Belongs to the glycosyl hydrolase 51 family%3B KEGG: bli:BL00345 alpha-N-arabinofuranosidase gene gene3190 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03191 S100027_03192 S100027_03192 S100027_03192 3028070 3028912 - L-arabinose transport system permease protein AraQ Cell membrane%3B Membrane%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system for L-arabinose. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3191 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03192 S100027_03193 S100027_03193 S100027_03193 3028912 3029856 - L-arabinose transport system permease protein AraP Cell membrane%3B Membrane%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system for L-arabinose. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3192 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03193 S100027_03194 S100027_03194 S100027_03194 3029887 3031200 - putative arabinose-binding protein Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Sugar transport%3B Transport%3B Part of the binding-protein-dependent transport system for L-arabinose. Belongs to the bacterial solute-binding protein 1 family gene gene3193 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03194 S100027_03195 S100027_03195 araM araM 3031197 3032402 - sn-glycerol-1-phosphate dehydrogenase Cytoplasm%3B Lipid biosynthesis%3B Lipid metabolism%3B Metal-binding%3B NAD%3B NADP%3B Nickel%3B Oxidoreductase%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species%3B Belongs to the glycerol-1-phosphate dehydrogenase family%3B KEGG: bli:BL00349 glycerol-1-phosphate dehydrogenase (NAD(P)+) gene gene3194 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03195 S100027_03196 S100027_03196 S100027_03196 3032419 3033105 - L-ribulose-5-phosphate 4-epimerase Arabinose catabolism%3B Carbohydrate metabolism%3B Isomerase%3B Metal-binding%3B Zinc%3B Belongs to the aldolase class II family. AraD/FucA subfamily%3B KEGG: sgl:SG1415 L-ribulose-5-phosphate 4-epimerase gene gene3195 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03196 S100027_03197 S100027_03197 S100027_03197 3033121 3034779 - Ribulokinase Arabinose catabolism%3B ATP-binding%3B Carbohydrate metabolism%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the ribulokinase family%3B KEGG: bsu:BSU28790 L-ribulokinase gene gene3196 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03197 S100027_03198 S100027_03198 S100027_03198 3034827 3036308 - L-arabinose isomerase Arabinose catabolism%3B Carbohydrate metabolism%3B Isomerase%3B Manganese%3B Metal-binding%3B Catalyzes the conversion of L-arabinose to L-ribulose%3B Belongs to the arabinose isomerase family%3B KEGG: bli:BL00352 L-arabinose isomerase gene gene3197 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03198 S100027_03199 S100027_03199 S100027_03199 3036573 3037535 - Arabinan endo-1%2C5-alpha-L-arabinosidase Calcium%3B Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Metal-binding%3B Secreted%3B Signal%3B Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the internal cleavage of alpha-(1->5)-L-arabinofuranosyl residues of linear 1%2C5-alpha-L-arabinan and of branched sugar beet arabinan. It displays no activity against heavily substituted arabinans or a range of other polysaccharides (larch wood arabinogalactan%2C wheat arabinoxylan and p-nitrophenyl-alpha-L- arabinofuranoside). The enzyme activity is progressively reduced as alpha-(1->5)-chains become shorter or more highly substituted%3B Belongs to the glycosyl hydrolase 43 family%3B KEGG: bli:BL00353 arabinan endo-1%2C5-alpha-L-arabinosidase gene gene3198 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03199 S100027_03200 S100027_03200 S100027_03200 3037692 3038777 - Cellulase Aminopeptidase%3B Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Putative aminopeptidase. Belongs to the peptidase M42 family%3B KEGG: bsu:BSU28820 endoglucanase gene gene3199 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03200 S100027_03201 S100027_03201 S100027_03201 3038951 3039352 + Sigma-w pathway protein YsdB Membrane%3B Transmembrane%3B Transmembrane helix%3B May mediate a negative feedback loop that down-regulates the expression of the sigma-W regulon following the activation of sigma-W in response to conditions of cell envelope stress. Might interact with and inhibit the activity of the protease PrsW%2C or could bind to the anti-sigma-W factor RsiW and thereby protect it from PrsW-mediated cleavage gene gene3200 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03201 S100027_03202 S100027_03202 S100027_03202 3039369 3039611 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3201 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03202 S100027_03203 S100027_03203 S100027_03203 3039749 3040108 - 50S ribosomal protein L20%2C chloroplastic Chloroplast%3B Plastid%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA editing%3B RNA-binding%3B rRNA-binding%3B Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit%3B Belongs to the ribosomal protein L20P family gene gene3202 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03203 S100027_03204 S100027_03204 S100027_03204 3040142 3040342 - 50S ribosomal protein L35 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L35P family gene gene3203 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03204 S100027_03205 S100027_03205 S100027_03205 3040360 3040995 - Translation initiation factor IF-3 Cytoplasm%3B Initiation factor%3B Protein biosynthesis%3B IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits%2C thus enhancing the availability of 30S subunits on which protein synthesis initiation begins%3B Belongs to the IF-3 family gene gene3204 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03205 S100027_03206 S100027_03206 S100027_03206 3041214 3041897 - Antiholin-like protein LrgB Cell membrane%3B Cytolysis%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Inhibits the expression or activity of extracellular murein hydrolases by interacting%2C possibly with LrgA%2C with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD)%2C possibly triggering PCD in response to antibiotics and environmental stresses%3B Belongs to the CidB/LrgB family. LrgB subfamily gene gene3205 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03206 S100027_03207 S100027_03207 S100027_03207 3041921 3042334 - Antiholin-like protein LrgA Cell membrane%3B Cytolysis%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Inhibits the expression or activity of extracellular murein hydrolases by interacting%2C possibly with LrgB%2C with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD)%2C possibly triggering PCD in response to antibiotics and environmental stresses%3B Belongs to the CidA/LrgA family. LrgA subfamily gene gene3206 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03207 S100027_03208 S100027_03208 S100027_03208 3042571 3044127 + Alkaline phosphatase Hydrolase%3B Signal%3B Stress response%3B Belongs to the PhoD family%3B KEGG: bli:BL05301 alkaline phosphatase D gene gene3207 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03208 S100027_03209 S100027_03209 S100027_03209 3044183 3044905 - Chemotaxis response regulator protein-glutamate methylesterase Chemotaxis%3B Cytoplasm%3B Hydrolase%3B Phosphoprotein%3B Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene3208 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03209 S100027_03210 S100027_03210 lytS lytS 3044880 3046664 - Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism. Contains 1 GAF domain%3B Contains 1 histidine kinase domain%3B KEGG: bli:BL00380 two-component system%2C LytT family%2C sensor histidine kinase LytS gene gene3209 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03210 S100027_03211 S100027_03211 S100027_03211 3046824 3047051 - hypothetical protein gene gene3210 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03211 S100027_03212 S100027_03212 S100027_03212 3047304 3048116 + Putative uncharacterized hydrolase YsaA Hydrolase%3B Belongs to the HAD-like hydrolase superfamily gene gene3211 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03212 S100027_03213 S100027_03213 S100027_03213 3048148 3050079 - Threonine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B Zinc%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: bli:BL00382 threonyl-tRNA synthetase gene gene3212 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03213 S100027_03214 S100027_03214 S100027_03214 3050423 3051265 - uncharacterized protein gene gene3213 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03214 S100027_03215 S100027_03215 S100027_03215 3051342 3051971 - TVP38/TMEM64 family membrane protein YtxB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the TVP38/TMEM64 family gene gene3214 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03215 S100027_03216 S100027_03216 S100027_03216 3052010 3052945 - Primosomal protein DnaI ATP-binding%3B DNA replication%3B Nucleotide-binding%3B Primosome. gene gene3215 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03216 S100027_03217 S100027_03217 S100027_03217 3052960 3054384 - Replication initiation and membrane attachment protein ATP-binding%3B DNA replication%3B DNA-binding%3B Nucleotide-binding%3B Primosome. gene gene3216 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03217 S100027_03218 S100027_03218 S100027_03218 3054501 3054959 - Transcriptional repressor NrdR ATP-binding%3B DNA-binding%3B Metal-binding%3B Nucleotide-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Zinc%3B Zinc-finger%3B Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes%3B Belongs to the NrdR family%3B Contains 1 ATP-cone domain gene gene3217 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03218 S100027_03219 S100027_03219 S100027_03219 3054975 3055367 - hypothetical protein gene gene3218 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03219 S100027_03220 S100027_03220 speD speD 3055549 3055935 - Adenosylmethionine decarboxylase Autocatalytic cleavage%3B Decarboxylase%3B Lyase%3B Polyamine biosynthesis%3B Pyruvate%3B S-adenosyl-L-methionine%3B Schiff base%3B Spermidine biosynthesis%3B Zymogen%3B Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet)%2C the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine%3B Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily%3B KEGG: nis:NIS_1526 S-adenosylmethionine decarboxylase gene gene3219 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03220 S100027_03221 S100027_03221 gapA gapA 3056172 3057194 - Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) Cytoplasm%3B Glycolysis%3B NAD%3B Nucleotide-binding%3B Oxidoreductase%3B Involved in the glycolysis. Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1%2C3- bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue%2C and this hemiacetal intermediate is then oxidized to a thioester%2C with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD%2C and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG%3B Belongs to the glyceraldehyde-3-phosphate dehydrogenase family%3B KEGG: eco:b1779 glyceraldehyde 3-phosphate dehydrogenase gene gene3220 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03221 S100027_03222 S100027_03222 S100027_03222 3057446 3058930 + Pectin lyase Lyase%3B Belongs to the polysaccharide lyase 1 family%3B KEGG: bli:BL00361 pectin lyase gene gene3221 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03222 S100027_03223 S100027_03223 coaE coaE 3058957 3059562 - Dephospho-CoA kinase ATP-binding%3B Coenzyme A biosynthesis%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A%3B Belongs to the CoaE family%3B Contains 1 DPCK (dephospho-CoA kinase) domain%3B KEGG: ppr:PBPRA3204 dephospho-CoA kinase gene gene3222 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03223 S100027_03224 S100027_03224 S100027_03224 3059580 3060212 - Putative membrane protein YtaF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3223 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03224 S100027_03225 S100027_03225 mutM mutM 3060433 3061260 - DNA-formamidopyrimidine glycosylase DNA damage%3B DNA repair%3B DNA-binding%3B Glycosidase%3B Hydrolase%3B Lyase%3B Metal-binding%3B Multifunctional enzyme%3B Zinc%3B Zinc-finger%3B Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines%2C such as 7%2C8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates%3B Belongs to the FPG family%3B Contains 1 FPG-type zinc finger%3B KEGG: dma:DMR_16970 formamidopyrimidine-DNA glycosylase gene gene3224 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03225 S100027_03226 S100027_03226 S100027_03226 3061279 3063918 - DNA-directed DNA polymerase DNA damage%3B DNA repair%3B DNA replication%3B DNA-binding%3B DNA-directed DNA polymerase%3B Exonuclease%3B Hydrolase%3B Nuclease%3B Nucleotidyltransferase%3B Transferase%3B In addition to polymerase activity%2C this DNA polymerase exhibits 3' to 5' and 5' to 3' exonuclease activity%3B Belongs to the DNA polymerase type-A family%3B Contains 1 3'-5' exonuclease domain%3B Contains 1 5'-3' exonuclease domain%3B KEGG: bsu:BSU29090 DNA polymerase I gene gene3225 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03226 S100027_03227 S100027_03227 S100027_03227 3064174 3065919 - Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphate transport%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Two-component regulatory system%3B Member of the two-component regulatory system PhoP/PhoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoP in response to environmental signals. Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bsu:BSU29100 two-component system%2C OmpR family%2C phosphate regulon sensor histidine kinase PhoR gene gene3226 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03227 S100027_03228 S100027_03228 S100027_03228 3065912 3066634 - Phosphate regulon transcriptional regulatory protein Activator%3B Cytoplasm%3B DNA-binding%3B Phosphate transport%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Transport%3B Two-component regulatory system%3B This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited (By similarity)%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3227 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03228 S100027_03229 S100027_03229 S100027_03229 3066978 3067916 - Malate dehydrogenase NAD%3B Oxidoreductase%3B Phosphoprotein%3B Tricarboxylic acid cycle%3B Catalyzes the reversible oxidation of malate to oxaloacetate%3B Belongs to the LDH/MDH superfamily. MDH type 3 family%3B KEGG: bli:BL00397 malate dehydrogenase gene gene3228 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03229 S100027_03230 S100027_03230 idh1 idh1 3067965 3069281 - Isocitrate dehydrogenase (NADP(+)) Acetylation%3B Glyoxylate bypass%3B Magnesium%3B Manganese%3B Metal-binding%3B NADP%3B Oxidoreductase%3B Phosphoprotein%3B Tricarboxylic acid cycle%3B Belongs to the isocitrate and isopropylmalate dehydrogenases family%3B KEGG: bld:BLi03061 isocitrate dehydrogenase gene gene3229 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03230 S100027_03231 S100027_03231 S100027_03231 3069404 3070522 - Citrate (Si)-synthase Allosteric enzyme%3B Phosphoprotein%3B Transferase%3B Tricarboxylic acid cycle%3B Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect. Belongs to the citrate synthase family%3B KEGG: bsu:BSU29140 citrate synthase gene gene3230 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03231 S100027_03232 S100027_03232 S100027_03232 3070945 3071409 - UPF0756 membrane protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0756 family gene gene3231 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03232 S100027_03233 S100027_03233 S100027_03233 3071511 3072626 + UPF0118 membrane protein YtvI Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0118 (PerM) family gene gene3232 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03233 S100027_03234 S100027_03234 S100027_03234 3072669 3073055 - UPF0716 protein YtzA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0716 (FxsA) family gene gene3233 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03234 S100027_03235 S100027_03235 S100027_03235 3073368 3075125 - Pyruvate kinase ATP-binding%3B Cytoplasm%3B Glycolysis%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Potassium%3B Pyruvate%3B Transferase%3B Belongs to the pyruvate kinase family%3B KEGG: eco:b1676 pyruvate kinase gene gene3234 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03235 S100027_03236 S100027_03236 pfkA pfkA 3075150 3076109 - 6-phosphofructokinase Allosteric enzyme%3B ATP-binding%3B Cytoplasm%3B Glycolysis%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Transferase%3B Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1%2C6-bisphosphate by ATP%2C the first committing step of glycolysis%3B Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily%3B KEGG: eco:b3916 6-phosphofructokinase 1 gene gene3235 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03236 S100027_03237 S100027_03237 accA accA 3076352 3077329 - Acetyl-CoA carboxylase ATP-binding%3B Cytoplasm%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Ligase%3B Lipid biosynthesis%3B Lipid metabolism%3B Nucleotide-binding%3B Component of the acetyl coenzyme A carboxylase (ACC) complex. First%2C biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA%3B Belongs to the AccA family%3B KEGG: bli:BL00404 acetyl-CoA carboxylase carboxyl transferase subunit alpha%3B overlaps another CDS with the same product name gene gene3236 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03237 S100027_03238 S100027_03238 accD accD 3077314 3078189 - Acetyl-CoA carboxylase ATP-binding%3B Cytoplasm%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Ligase%3B Lipid biosynthesis%3B Lipid metabolism%3B Metal-binding%3B Nucleotide-binding%3B Zinc%3B Zinc-finger%3B Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA%3B Belongs to the AccD/PCCB family%3B KEGG: bli:BL00405 acetyl-CoA carboxylase carboxyl transferase subunit beta%3B overlaps another CDS with the same product name gene gene3237 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03238 S100027_03239 S100027_03239 sfcA sfcA 3078550 3079785 - Malate dehydrogenase (oxaloacetate-decarboxylating) Metal-binding%3B NAD%3B Oxidoreductase%3B Belongs to the malic enzymes family%3B KEGG: bsu:BSU29220 malate dehydrogenase (oxaloacetate-decarboxylating) gene gene3238 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03239 S100027_03240 S100027_03240 dnaE dnaE 3079928 3083272 - DNA-directed DNA polymerase Cytoplasm%3B DNA replication%3B DNA-directed DNA polymerase%3B Nucleotidyltransferase%3B Transferase%3B DNA polymerase III is a complex%2C multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase (By similarity)%3B Belongs to the DNA polymerase type-C family. DnaE subfamily%3B KEGG: bsu:BSU29230 DNA polymerase III subunit alpha gene gene3239 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03240 S100027_03241 S100027_03241 S100027_03241 3083412 3083753 + Sporulation membrane protein YtrH Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Involved in sporulation. May contribute to cortex formation or stability gene gene3240 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03241 S100027_03242 S100027_03242 S100027_03242 3083750 3084253 + Sporulation membrane protein YtrI Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Involved in sporulation gene gene3241 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03242 S100027_03243 S100027_03243 S100027_03243 3084366 3084545 + uncharacterized protein gene gene3242 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03243 S100027_03244 S100027_03244 S100027_03244 3084661 3085605 - Bifunctional oligoribonuclease and PAP phosphatase NrnA Exonuclease%3B Hydrolase%3B Nuclease%3B Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA and DNA oligonucleotides with a length of 5 nucleotides and shorter%2C with a preference for 3-mers. Directionality is controversia%3B shown to degrade 5-mers and less in a 3' to 5' direction (PubMed:17586819)%2C and 11-mers in a 5' to 3' direction (PubMed:21087930). Converts 3'(2')- phosphoadenosine 5'-phosphate (PAP) to AMP%3B Belongs to the NrnA oligoribonuclease family gene gene3243 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03244 S100027_03245 S100027_03245 S100027_03245 3085752 3086054 + putative membrane protein YtpI Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3244 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03245 S100027_03246 S100027_03246 S100027_03246 3086083 3087414 - IMP dehydrogenase CBS domain%3B Repeat%3B Contains 2 CBS domains%3B KEGG: afu:AF_1259 IMP dehydrogenase gene gene3245 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03246 S100027_03247 S100027_03247 S100027_03247 3087498 3088055 - Negative transcription regulator PadR Cytoplasm%3B Repressor%3B Transcription%3B Transcription regulation%3B Negative transcriptional regulator of padC phenolic acid decarboxylase gene gene3246 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03247 S100027_03248 S100027_03248 S100027_03248 3088172 3088858 - UPF0173 metal-dependent hydrolase Hydrolase%3B Belongs to the UPF0173 family gene gene3247 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03248 S100027_03249 S100027_03249 S100027_03249 3088893 3089702 - 3-oxoacyl-[acyl-carrier-protein] reductase Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: blh:BaLi_c31620 3-oxoacyl-(acyl-carrier protein) reductase gene gene3248 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03249 S100027_03250 S100027_03250 S100027_03250 3089833 3089976 - hypothetical protein gene gene3249 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03250 S100027_03251 S100027_03251 argH argH 3090051 3091430 - Argininosuccinate lyase Amino-acid biosynthesis%3B Arginine biosynthesis%3B Cytoplasm%3B Lyase%3B Belongs to the lyase 1 family. Argininosuccinate lyase subfamily%3B KEGG: bam:Bamb_6457 argininosuccinate lyase gene gene3250 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03251 S100027_03252 S100027_03252 argG argG 3091427 3092638 - Argininosuccinate synthase Amino-acid biosynthesis%3B Arginine biosynthesis%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Belongs to the argininosuccinate synthase family. Type 1 subfamily%3B KEGG: bli:BL00417 argininosuccinate synthase gene gene3251 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03252 S100027_03253 S100027_03253 S100027_03253 3092831 3093349 - Molybdenum cofactor biosynthesis protein Molybdenum cofactor biosynthesis%3B May be involved in the biosynthesis of molybdopterin%3B Belongs to the MoaB/Mog family gene gene3252 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03253 S100027_03254 S100027_03254 ackA ackA 3093448 3094635 - Acetate kinase ATP-binding%3B Cytoplasm%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Transferase%3B Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction%3B Belongs to the acetokinase family%3B KEGG: tau:Tola_1703 acetate kinase gene gene3253 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03254 S100027_03255 S100027_03255 S100027_03255 3094865 3095851 - Site-specific DNA-methyltransferase (adenine-specific) To type I restriction system adenine methylases%3B KEGG: bli:BL00420 site-specific DNA-methyltransferase (adenine-specific) gene gene3254 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03255 S100027_03256 S100027_03256 S100027_03256 3095937 3096440 - Peroxiredoxin Antioxidant%3B Oxidoreductase%3B Peroxidase%3B Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)%3B Belongs to the AhpC/TSA family. Tpx subfamily%3B Contains 1 thioredoxin domain%3B KEGG: pbc:CD58_15555 thiol peroxidase%2C atypical 2-Cys peroxiredoxin gene gene3255 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03256 S100027_03257 S100027_03257 S100027_03257 3096586 3097044 - putative spore protein YtfJ Sporulation. gene gene3256 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03257 S100027_03258 S100027_03258 S100027_03258 3097057 3097740 - uncharacterized protein Signal. gene gene3257 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03258 S100027_03259 S100027_03259 S100027_03259 3097862 3098380 - putative membrane protein YteJ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Contains 1 RDD domain gene gene3258 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03259 S100027_03260 S100027_03260 sppA sppA 3098396 3099403 - Putative signal peptide peptidase SppA Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Serine protease%3B Transmembrane%3B Transmembrane helix%3B Digestion of cleaved signal peptides (By similarity). Required for efficient processing of precursors under conditions of hyper-secretion. Has a preference for leucine-rich substrate peptides%3B Belongs to the peptidase S49 family%3B KEGG: bsu:BSU29530 protease IV%3B Serine endopeptidases gene gene3259 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03260 S100027_03261 S100027_03261 S100027_03261 3099596 3100393 + NAD(+) kinase ATP-binding%3B Cytoplasm%3B Kinase%3B NAD%3B NADP%3B Nucleotide-binding%3B Transferase%3B Involved in the regulation of the intracellular balance of NAD and NADP%2C and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP%3B Belongs to the NAD kinase family%3B KEGG: bli:BL00367 NAD+ kinase gene gene3260 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03261 S100027_03262 S100027_03262 S100027_03262 3100455 3101090 - Putative efflux system component YhbJ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene3261 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03262 S100027_03263 S100027_03263 S100027_03263 3101093 3102715 - putative MFS-type transporter YubD Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene3262 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03263 S100027_03264 S100027_03264 S100027_03264 3102853 3103281 - putative HTH-type transcriptional regulator YxaD DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH marR-type DNA-binding domain gene gene3263 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03264 S100027_03265 S100027_03265 S100027_03265 3103307 3104896 - Acetate--CoA ligase ATP-binding%3B Ligase%3B Nucleotide-binding%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bsu:BSU29560 acetyl-CoA synthetase gene gene3264 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03265 S100027_03266 S100027_03266 S100027_03266 3105039 3105251 - Small%2C acid-soluble spore protein DNA-binding%3B Sporulation%3B SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. Belongs to the alpha/beta-type SASP family gene gene3265 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03266 S100027_03267 S100027_03267 S100027_03267 3105363 3106568 - putative tRNA sulfurtransferase ATP-binding%3B Cytoplasm%3B Nucleotide-binding%3B RNA-binding%3B Thiamine biosynthesis%3B Transferase%3B tRNA-binding%3B Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs%2C which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS%2C forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole%2C in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS%3B Belongs to the ThiI family%3B Contains 1 THUMP domain gene gene3266 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03267 S100027_03268 S100027_03268 S100027_03268 3106576 3107721 - Cysteine desulfurase Iron%3B Iron-sulfur%3B Metal-binding%3B Pyridoxal phosphate%3B Transferase%3B Catalyzes the removal of elemental sulfur from cysteine to produce alanine%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily%3B KEGG: bsu:BSU29590 cysteine desulfurase gene gene3267 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03268 S100027_03269 S100027_03269 S100027_03269 3107915 3109252 + Branched-chain amino acid transport system carrier protein BrnQ Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Component of the transport system for branched-chain amino acids (leucine%2C isoleucine and valine) Which is coupled to a proton motive force%3B Belongs to the branched chain amino acid transporter family gene gene3268 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03269 S100027_03270 S100027_03270 S100027_03270 3109421 3109753 + hypothetical protein gene gene3269 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03270 S100027_03271 S100027_03271 S100027_03271 3109723 3110583 + putative transposase-like protein DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene3270 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03271 S100027_03272 S100027_03272 S100027_03272 3110644 3112338 - Septation ring formation regulator EzrA Cell cycle%3B Cell division%3B Cell membrane%3B Coiled coil%3B Membrane%3B Septation%3B Transmembrane%3B Transmembrane helix%3B Negative regulator of FtsZ ring formatio%3B modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization%3B Belongs to the EzrA family gene gene3271 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03272 S100027_03273 S100027_03273 S100027_03273 3112527 3113339 + Histidinol-phosphatase Amino-acid biosynthesis%3B Histidine biosynthesis%3B Hydrolase%3B Belongs to the PHP hydrolase family. HisK subfamily%3B KEGG: bsu:BSU29620 histidinol-phosphatase (PHP family) gene gene3272 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03273 S100027_03274 S100027_03274 S100027_03274 3113332 3113970 - putative HTH-type transcriptional regulator YttP DNA-binding%3B Repressor%3B Stress response%3B Transcription%3B Transcription regulation%3B Contains 1 HTH tetR-type DNA-binding domain gene gene3273 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03274 S100027_03275 S100027_03275 S100027_03275 3114099 3114593 + Protein YtsP Belongs to the free Met sulfoxide reductase family gene gene3274 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03275 S100027_03276 S100027_03276 S100027_03276 3114607 3116307 - Diguanylate cyclase Contains 1 GGDEF domain%3B KEGG: yen:YE2425 diguanylate cyclase gene gene3275 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03276 S100027_03277 S100027_03277 S100027_03277 3116637 3117239 + 30S ribosomal protein S4 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B One of the primary rRNA binding proteins%2C it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit%3B With S5 and S12 plays an important role in translational accuracy%3B Belongs to the ribosomal protein S4P family%3B Contains 1 S4 RNA-binding domain gene gene3276 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03277 S100027_03278 S100027_03278 S100027_03278 3117275 3117463 - hypothetical protein gene gene3277 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03278 S100027_03279 S100027_03279 S100027_03279 3117541 3117771 + hypothetical protein gene gene3278 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03279 S100027_03280 S100027_03280 S100027_03280 3118060 3118497 - Inner membrane protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B To E. coli YhaI gene gene3279 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03280 S100027_03281 S100027_03281 S100027_03281 3118993 3119763 - UPF0173 protein YddR Hydrolase%3B Belongs to the UPF0173 family gene gene3280 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03281 S100027_03282 S100027_03282 S100027_03282 3119887 3120306 + Proline dehydrogenase transcriptional activator Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Transcriptional activator of the putA gene in response to proline. Contains 1 HTH asnC-type DNA-binding domain gene gene3281 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03282 S100027_03283 S100027_03283 S100027_03283 3120357 3120503 - hypothetical protein gene gene3282 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03283 S100027_03284 S100027_03284 S100027_03284 3120636 3121901 - Tyrosine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B RNA-binding%3B Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)%3B Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily%3B Contains 1 S4 RNA-binding domain%3B KEGG: bli:BL00439 tyrosyl-tRNA synthetase gene gene3283 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03284 S100027_03285 S100027_03285 S100027_03285 3122243 3123961 - Acetate--CoA ligase Acetylation%3B ATP-binding%3B Ligase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Catalyzes the conversion of acetate into acetyl-CoA (AcCoA)%2C an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction%2C AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction%2C it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA%2C forming the product AcCoA (By similarity). Has a role in growth and sporulation on acetate%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bsu:BSU29680 acetyl-CoA synthetase gene gene3284 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03285 S100027_03286 S100027_03286 acuA acuA 3124117 3124749 + Acetoin utilization protein AcuA Acetoin catabolism%3B Acyltransferase%3B Transferase%3B Part of the acuABC operon%2C which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bsu:BSU29690 acetoin utilization protein AcuA%3B Transferring groups other than amino-acyl groups gene gene3285 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03286 S100027_03287 S100027_03287 S100027_03287 3124771 3125415 + Acetoin utilization protein AcuB Acetoin catabolism%3B CBS domain%3B Repeat%3B Sporulation%3B Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source. Contains 2 CBS domains gene gene3286 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03287 S100027_03288 S100027_03288 S100027_03288 3125412 3126572 + Acetoin utilization protein AcuC Acetoin catabolism%3B Sporulation%3B Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source. Belongs to the histone deacetylase family gene gene3287 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03288 S100027_03289 S100027_03289 S100027_03289 3126634 3127323 - putative 24.6 kDa protein in ccpA 3'region Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B May be involved in some transport function. Belongs to the MotB family%3B Contains 1 OmpA-like domain gene gene3288 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03289 S100027_03290 S100027_03290 S100027_03290 3127313 3128131 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B May be involved in some transport function. Belongs to the MotA family gene gene3289 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03290 S100027_03291 S100027_03291 S100027_03291 3128227 3129228 - Catabolite control protein Activator%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA)%2C which ensures optimal energy usage under diverse conditions. Interacts with either P-Ser-HPr or P-Ser-Crh%2C leading to the formation of a complex that binds to DNA at the catabolite-response elements (cre). Binding to DNA allows activation or repression of many different genes and operons%3B Contains 1 HTH lacI-type DNA-binding domain gene gene3290 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03291 S100027_03292 S100027_03292 aroG aroG 3129544 3130620 - 3-deoxy-7-phosphoheptulonate synthase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Isomerase%3B Multifunctional enzyme%3B Phosphoprotein%3B Transferase%3B Belongs to the class-I DAHP synthase family%3B Contains 1 chorismate mutase domain%3B KEGG: bsu:BSU29750 3-deoxy-7-phosphoheptulonate synthase / chorismate mutase gene gene3291 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03292 S100027_03293 S100027_03293 S100027_03293 3130731 3130889 - hypothetical protein gene gene3292 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03293 S100027_03294 S100027_03294 S100027_03294 3130831 3131280 - UPF0134 protein Belongs to the UPF0134 family gene gene3293 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03294 S100027_03295 S100027_03295 S100027_03295 3131430 3131756 - uncharacterized protein gene gene3294 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03295 S100027_03296 S100027_03296 S100027_03296 3131777 3132193 - uncharacterized protein To C. plantagineum desiccation-related protein clone PCC3-06 gene gene3295 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03296 S100027_03297 S100027_03297 S100027_03297 3132197 3132619 - UPF0478 protein YtxG Coiled coil%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0478 family gene gene3296 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03297 S100027_03298 S100027_03298 murC murC 3132786 3134084 - UDP-N-acetylmuramate--L-alanine ligase ATP-binding%3B Cell cycle%3B Cell division%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Peptidoglycan synthesis%3B Cell wall formation%3B Belongs to the MurCDEF family%3B KEGG: bsu:BSU29790 UDP-N-acetylmuramate--alanine ligase gene gene3297 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03298 S100027_03299 S100027_03299 S100027_03299 3134350 3137256 - DNA translocase SftA ATP-binding%3B Cell cycle%3B Cell division%3B Chromosome partition%3B Cytoplasm%3B DNA-binding%3B Nucleotide-binding%3B Required for the accurate completion of chromosome partitioning%2C in part by promoting efficient resolution of chromosome dimers%2C before the formation of the division septum. Binds to DNA in a non-specific manner. Shows ATPase activity. Not required for cytokinesis%3B Belongs to the FtsK/SpoIIIE/SftA family%3B Contains 1 FtsK domain gene gene3298 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03299 S100027_03300 S100027_03300 S100027_03300 3137441 3138046 - Putative tRNA-binding protein YtpR RNA-binding%3B tRNA-binding%3B Contains 1 tRNA-binding domain gene gene3299 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03300 S100027_03301 S100027_03301 S100027_03301 3138065 3138874 - UPF0354 protein Belongs to the UPF0354 family gene gene3300 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03301 S100027_03302 S100027_03302 S100027_03302 3138894 3139214 - Thioredoxin-like protein YtpP Disulfide bond%3B Redox-active center%3B Contains 1 thioredoxin domain gene gene3301 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03302 S100027_03303 S100027_03303 S100027_03303 3139504 3139950 + uncharacterized protein gene gene3302 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03303 S100027_03304 S100027_03304 pepA pepA 3140003 3141076 - Glutamyl aminopeptidase Aminopeptidase%3B Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Belongs to the peptidase M42 family%3B KEGG: cml:BN424_1132 glutamyl aminopeptidase gene gene3303 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03304 S100027_03305 S100027_03305 S100027_03305 3141213 3141527 + uncharacterized protein gene gene3304 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03305 S100027_03306 S100027_03306 S100027_03306 3141564 3143261 - Malate dehydrogenase (oxaloacetate-decarboxylating) Metal-binding%3B NAD%3B Oxidoreductase%3B Belongs to the malic enzymes family%3B KEGG: bli:BL00044 malate dehydrogenase (oxaloacetate-decarboxylating) gene gene3305 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03306 S100027_03307 S100027_03307 S100027_03307 3143334 3144179 - putative quorum-quenching lactonase YtnP Hydrolase%3B Metal-binding%3B Phosphoprotein%3B Zinc%3B Probable hydrolase that is able to inhibit the signaling pathway required for the streptomycin production and development of aerial mycelium in S. griseus. Thus%2C serves as a defensive strategy against competing bacteria. The putative target for YtnP may be a gamma-butyrolactone termed A factor%2C which is the quorum- sensing signaling molecule that positively regulates streptomycin production and development of aerial hyphae in S. griseus%3B Belongs to the metallo-beta-lactamase superfamily gene gene3306 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03307 S100027_03308 S100027_03308 trmB trmB 3144275 3144916 - tRNA (guanine(46)-N(7))-methyltransferase Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B tRNA processing%3B Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family%3B KEGG: bsu:BSU29900 tRNA (guanine-N7-)-methyltransferase gene gene3307 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03308 S100027_03309 S100027_03309 S100027_03309 3145097 3145375 + uncharacterized protein gene gene3308 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03309 S100027_03310 S100027_03310 S100027_03310 3145370 3146173 - Putative phosphotransferase YtmP ATP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the aminoglycoside phosphotransferase family gene gene3309 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03310 S100027_03311 S100027_03311 S100027_03311 3146362 3148062 - Pullulanase Glycosidase%3B Hydrolase%3B Belongs to the glycosyl hydrolase 13 family%3B KEGG: bli:BL00040 pullulanase%3B overlaps another CDS with the same product name gene gene3310 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03311 S100027_03312 S100027_03312 S100027_03312 3148059 3148493 - Pullulanase KEGG: bli:BL00040 pullulanase%3B overlaps another CDS with the same product name gene gene3311 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03312 S100027_03313 S100027_03313 cerK cerK 3148520 3149440 - Ceramide kinase ATP-binding%3B Kinase%3B Lipid biosynthesis%3B Lipid metabolism%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG). In fact%2C is not able to exhibit diacylglycerol kinase activity in vitro. Belongs to the diacylglycerol/lipid kinase family%3B Contains 1 DAGKc domain%3B KEGG: ppp:PHYPADRAFT_158844 ceramide kinase gene gene3312 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03313 S100027_03314 S100027_03314 S100027_03314 3149493 3150434 - uncharacterized protein Coiled coil. gene gene3313 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03314 S100027_03315 S100027_03315 ligT ligT 3150418 3151023 - RNA 2'%2C3'-cyclic phosphodiesterase Hydrolase%3B Hydrolyzes RNA 2'%2C3'-cyclic phosphodiester to an RNA 2'- phosphomonoester%3B Belongs to the 2H phosphoesterase superfamily. ThpR family%3B KEGG: bli:BL00037 2'-5' RNA ligase%3B Forming phosphoric ester bonds gene gene3314 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03315 S100027_03316 S100027_03316 S100027_03316 3151161 3152093 + Cysteine synthase Amino-acid biosynthesis%3B Cysteine biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Belongs to the cysteine synthase/cystathionine beta- synthase family%3B KEGG: bli:BL00070 cysteine synthase A gene gene3315 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03316 S100027_03317 S100027_03317 S100027_03317 3152897 3153034 - hypothetical protein gene gene3316 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03317 S100027_03318 S100027_03318 dapE dapE 3153051 3154442 - Succinyl-diaminopimelate desuccinylase Dipeptidase%3B Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Zinc%3B Belongs to the peptidase M20A family%3B KEGG: bli:BL00035 succinyl-diaminopimelate desuccinylase gene gene3317 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03318 S100027_03319 S100027_03319 S100027_03319 3154550 3155857 + Guanine/hypoxanthine permease PbuO Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the uptake of the purine bases hypoxanthine and guanine. May work at purine concentrations higher than 100 uM%3B Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2. A. 1. 40) subfamily gene gene3318 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03319 S100027_03320 S100027_03320 S100027_03320 3156190 3156411 + putative HTH-type transcriptional regulator YtzE DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH deoR-type DNA-binding domain gene gene3319 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03320 S100027_03321 S100027_03321 rsuA rsuA 3156532 3157254 - 16S rRNA pseudouridine(516) synthase Isomerase%3B RNA-binding%3B Belongs to the pseudouridine synthase RsuA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: par:Psyc_0024 16S rRNA pseudouridine516 synthase gene gene3320 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03321 S100027_03322 S100027_03322 S100027_03322 3157294 3158937 - putative cell division protein YtgP Cell cycle%3B Cell division%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B May play a role in cell division%2C although it is not essential for growth%3B Belongs to the polysaccharide synthase family gene gene3321 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03322 S100027_03323 S100027_03323 S100027_03323 3159157 3160431 + uncharacterized protein gene gene3322 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03323 S100027_03324 S100027_03324 S100027_03324 3160659 3162197 + Glycine betaine transporter OpuD Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B High-affinity uptake of glycine betaine. Does not mediate either carnitine or choline uptake%3B Belongs to the BCCT transporter (TC 2. A. 15) family gene gene3323 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03324 S100027_03325 S100027_03325 S100027_03325 3162233 3162415 - Sporulation protein cse60 Sporulation. gene gene3324 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03325 S100027_03326 S100027_03326 S100027_03326 3162591 3162908 - UPF0033 protein YrkF Belongs to the UPF0033 family%3B Contains 1 rhodanese domain gene gene3325 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03326 S100027_03327 S100027_03327 S100027_03327 3162988 3163122 - hypothetical protein gene gene3326 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03327 S100027_03328 S100027_03328 S100027_03328 3163119 3163925 - Response regulator aspartate phosphatase Hydrolase%3B Protein phosphatase%3B Repeat%3B TPR repeat%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bha:BH4014 response regulator aspartate phosphatase G%3B Acting on ester bonds gene gene3327 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03328 S100027_03329 S100027_03329 S100027_03329 3164332 3164691 - hypothetical protein gene gene3328 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03329 S100027_03330 S100027_03330 S100027_03330 3164728 3165375 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3329 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03330 S100027_03331 S100027_03331 iolG iolG 3165392 3166669 - Inositol 2-dehydrogenase Oxidoreductase%3B Signal%3B May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: rhi:NGR_b04530 myo-inositol 2-dehydrogenase / D-chiro-inositol 1-dehydrogenase gene gene3330 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03331 S100027_03332 S100027_03332 S100027_03332 3166689 3167183 - Putative lipoprotein YteS Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls gene gene3331 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03332 S100027_03333 S100027_03333 S100027_03333 3167180 3168301 - Unsaturated rhamnogalacturonyl hydrolase Cytoplasm%3B Glycosidase%3B Hydrolase%3B Catalyzes the hydrolysis of unsaturated rhamnogalacturonan disaccharide to yield unsaturated D- galacturonic acid and L-rhamnose. It cannot act on unsaturated glucuronyl hydrolase (UGL) substrates containing unsaturated D- glucuronic acid at the non-reducing terminus%2C although the active pockets of YesR and UGL are very similar%3B Belongs to the glycosyl hydrolase 105 family%3B KEGG: bli:BL00024 unsaturated rhamnogalacturonyl hydrolase gene gene3332 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03333 S100027_03334 S100027_03334 S100027_03334 3168330 3169295 - putative multiple-sugar transport system permease YteP Cell membrane%3B Membrane%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane. May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene3333 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03334 S100027_03335 S100027_03335 S100027_03335 3169511 3171820 + Histidine kinase Cell membrane%3B DNA-binding%3B Membrane%3B Transcription%3B Transcription regulation%3B Transmembrane%3B Transmembrane helix%3B Contains 1 HTH araC/xylS-type DNA-binding domain%3B KEGG: pod:PODO_24995 two-component system%2C sensor histidine kinase YesM gene gene3334 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03335 S100027_03336 S100027_03336 S100027_03336 3172054 3173559 - Putative ABC transporter peptide-binding protein YtcQ Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Probably part of a binding-protein-dependent transport system%3B Belongs to the bacterial solute-binding protein 1 family gene gene3335 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03336 S100027_03337 S100027_03337 S100027_03337 3173576 3174424 - putative ABC transporter permease protein YtcP Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3336 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03337 S100027_03338 S100027_03338 S100027_03338 3174595 3175359 - uncharacterized protein Belongs to the NAD(P)-dependent epimerase/dehydratase family gene gene3337 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03338 S100027_03339 S100027_03339 S100027_03339 3175377 3176264 - Putative hydrolase Hydrolase%3B Belongs to the dienelactone hydrolase family gene gene3338 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03339 S100027_03340 S100027_03340 S100027_03340 3176296 3177546 - putative amino acid permease YecA Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene3339 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03340 S100027_03341 S100027_03341 S100027_03341 3177675 3178568 + putative HTH-type transcriptional regulator YwqM Cytoplasm%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH lysR-type DNA-binding domain gene gene3340 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03341 S100027_03342 S100027_03342 S100027_03342 3178574 3178978 - Prolyl oligopeptidase KEGG: vfi:VF_A0660 prolyl oligopeptidase gene gene3341 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03342 S100027_03343 S100027_03343 larS larS 3179109 3181523 - Leucine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: dvu:DVU1196 leucyl-tRNA synthetase gene gene3342 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03343 S100027_03344 S100027_03344 S100027_03344 3181945 3182274 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3343 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03344 S100027_03345 S100027_03345 S100027_03345 3182495 3183676 - putative MFS-type transporter YttB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene3344 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03345 S100027_03346 S100027_03346 S100027_03346 3183796 3184620 - putative D-methionine-binding lipoprotein MetQ Amino-acid transport%3B Cell outer membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B This protein is a component of a D-methionine permease%2C a binding protein-dependent%2C ATP-driven transport system%3B Belongs to the NlpA lipoprotein family gene gene3345 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03346 S100027_03347 S100027_03347 S100027_03347 3184916 3185596 + putative membrane protein YttA Cell membrane%3B Coiled coil%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3346 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03347 S100027_03348 S100027_03348 S100027_03348 3185624 3186916 - ABC transporter permease YtrF Cell membrane%3B Coiled coil%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transmembrane%3B Transmembrane helix%3B Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation%3B Belongs to the ABC-4 integral membrane protein family gene gene3347 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03348 S100027_03349 S100027_03349 S100027_03349 3186945 3187643 - ABC transporter ATP-binding protein YtrE ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene3348 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03349 S100027_03350 S100027_03350 S100027_03350 3187669 3188646 - putative ABC transporter permease YtrC Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation%3B Belongs to the ABC-5 integral membrane protein family gene gene3349 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03350 S100027_03351 S100027_03351 S100027_03351 3188640 3189518 - L-arabinose transport ATP-binding protein AraG ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Repeat%3B Sugar transport%3B Transport%3B Part of the binding-protein-dependent transport system for L-arabinose. Probably responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 2 ABC transporter domains gene gene3350 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03351 S100027_03352 S100027_03352 S100027_03352 3189511 3189903 - HTH-type transcriptional repressor YtrA DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Negatively regulates ABC transporter complex ytrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation%3B Contains 1 HTH gntR-type DNA-binding domain gene gene3351 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03352 S100027_03353 S100027_03353 S100027_03353 3189946 3190074 - hypothetical protein gene gene3352 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03353 S100027_03354 S100027_03354 S100027_03354 3190200 3190472 - uncharacterized protein Coiled coil. gene gene3353 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03354 S100027_03355 S100027_03355 S100027_03355 3190625 3191593 + Putative protein YtqA 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B S-adenosyl-L-methionine%3B Belongs to the radical SAM superfamily gene gene3354 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03355 S100027_03356 S100027_03356 S100027_03356 3191590 3192174 + Putative rRNA methylase YtqB Methyltransferase%3B Transferase%3B Belongs to the methyltransferase superfamily gene gene3355 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03356 S100027_03357 S100027_03357 S100027_03357 3192355 3193605 + Proton glutamate symport protein Cell membrane%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B This carrier protein is part of the Na(+)-dependent%2C binding-protein-independent glutamate-aspartate transport system. Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family gene gene3356 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03357 S100027_03358 S100027_03358 ytpB ytpB 3193646 3194725 - Tetraprenyl-beta-curcumene synthase Lyase%3B Catalyzes the transformation of a linear C35 prenyl diphosphate chain to form tetraprenyl-beta-curcumene%3B KEGG: bsu:BSU30500 tetraprenyl-beta-curcumene synthase gene gene3357 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03358 S100027_03359 S100027_03359 pldB pldB 3194740 3195519 - Lysophospholipase Antibiotic biosynthesis%3B Hydrolase%3B Serine esterase%3B Phospholipase involved in the biosynthesis of the antibiotic bacilysocin. It probably catalyzes the hydrolysis of the 2-sn-acyl moiety of phosphatidylglycerol to produce bacilysocin (lysophosphatidylglycerol). Is also able to catalyze the hydrolysis reaction of one acyl bond in phosphatidylcholine in vitro (actual cleavage point is unknown)%2C resulting in lysophosphatidylcholine%3B Belongs to the AB hydrolase superfamily%3B KEGG: bli:BL00003 lysophospholipase gene gene3358 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03359 S100027_03360 S100027_03360 S100027_03360 3195563 3196081 + putative transferase YtoA Transferase%3B Belongs to the transferase hexapeptide repeat family gene gene3359 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03360 S100027_03361 S100027_03361 S100027_03361 3196258 3196782 + Undecaprenyl-diphosphate phosphatase KEGG: bli:BL00058 undecaprenyl-diphosphatase gene gene3360 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03361 S100027_03362 S100027_03362 S100027_03362 3196841 3197977 + GDP-mannose-dependent alpha-mannosyltransferase Glycosyltransferase%3B Lipid biosynthesis%3B Lipid metabolism%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B Catalyzes the addition of a mannose residue from GDP-D- mannose to GlcAGroAc2 to generate 1%2C2-di-O-C16/C18:1-(alpha-D- mannopyranosyl)-(1-4)-(alpha-D-glucopyranosyluronic acid)-(1-3)- glycerol(ManGlcAGroAc2)%3B Belongs to the glycosyltransferase group 1 family%3B KEGG: bcz:BCZK4513 null%3B Hexosyltransferases gene gene3361 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03362 S100027_03363 S100027_03363 S100027_03363 3198021 3199919 - Asparagine synthase (glutamine-hydrolyzing) Amino-acid biosynthesis%3B Asparagine biosynthesis%3B ATP-binding%3B Glutamine amidotransferase%3B Ligase%3B Nucleotide-binding%3B Main asparagine synthetase in vegetative cells. Belongs to the asparagine synthetase family%3B Contains 1 glutamine amidotransferase type-2 domain%3B KEGG: bsu:BSU30540 asparagine synthase (glutamine-hydrolysing) gene gene3362 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03363 S100027_03364 S100027_03364 metK metK 3200149 3201351 - Methionine adenosyltransferase ATP-binding%3B Cobalt%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B One-carbon metabolism%3B Potassium%3B Transferase%3B Catalyzes the formation of S-adenosylmethionine from methionine and ATP%3B Belongs to the AdoMet synthase family%3B KEGG: geo:Geob_1656 S-adenosylmethionine synthetase gene gene3363 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03364 S100027_03365 S100027_03365 pckA pckA 3202075 3203658 + Phosphoenolpyruvate carboxykinase (ATP) ATP-binding%3B Cytoplasm%3B Decarboxylase%3B Gluconeogenesis%3B Lyase%3B Manganese%3B Metal-binding%3B Nucleotide-binding%3B Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA%3B Belongs to the phosphoenolpyruvate carboxykinase [ATP] family%3B KEGG: bli:BL00839 phosphoenolpyruvate carboxykinase (ATP) gene gene3364 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03365 S100027_03366 S100027_03366 S100027_03366 3203908 3205092 + hypothetical protein gene gene3365 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03366 S100027_03367 S100027_03367 S100027_03367 3205133 3205375 - uncharacterized protein gene gene3366 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03367 S100027_03368 S100027_03368 dpp4 dpp4 3205400 3206200 - Dipeptidyl-peptidase IV Hydrolase%3B Protease%3B Serine protease%3B Belongs to the peptidase S9B family%3B KEGG: ehx:EMIHUDRAFT_466891 dipeptidyl-peptidase 4 gene gene3367 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03368 S100027_03369 S100027_03369 S100027_03369 3206308 3207300 + Putative binding protein YtlA Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Belongs to the bacterial solute-binding protein SsuA/TauA family gene gene3368 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03369 S100027_03370 S100027_03370 S100027_03370 3207313 3208101 + Lipoprotein-releasing system ATP-binding protein LolD ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins%2C from the inner membrane to the periplasmic chaperone%2C LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner%3B Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3. A. 1. 125) family%3B Contains 1 ABC transporter domain gene gene3369 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03370 S100027_03371 S100027_03371 S100027_03371 3208064 3208888 + putative ABC transporter permease protein YtlD Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene3370 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03371 S100027_03372 S100027_03372 S100027_03372 3208919 3209395 - 8-oxo-dGTP diphosphatase Hydrolase%3B Magnesium%3B Metal-binding%3B Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7%2C8-dihydro-8-oxoguanine%2C 8- oxo-dGTP) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A. T to G. C transversions (By similarity). Functions%2C in conjuction with MutT%2C to protect vegetatively growing cells from DNA-damaging agents such as H(2)O(2) or t-BHP (t-butylhydroperoxide). The 2 proteins do not however protect spores. According to PubMed:15576788%2C phosphohydrolase that catalyzes the hydrolysis of all common nucleoside triphosphates as well as of the mutagenic analog 8-oxo- dGTP. The high catalytic efficiency on dGTP is in contrast to results from PubMed:14761999. According to PubMed:14761999%2C catalyzes the hydrolysis of 8-oxo-dGTP with a specific activity 413 times higher than that exhibited against dGTP. Preferentially catalyzes the hydrolysis of 8-oxo-dGTP and 8-oxo-GTP. According to PubMed:15576788%2C hydrolyzes nucleoside triphosphates in a stepwise fashion through the diphosphate to the monophosphate%2C releasing two molecules of inorganic orthophosphate%3B Belongs to the Nudix hydrolase family%3B Contains 1 nudix hydrolase domain%3B KEGG: bsu:BSU30630 8-oxo-dGTP diphosphatase gene gene3371 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03372 S100027_03373 S100027_03373 S100027_03373 3209590 3209913 - hypothetical protein gene gene3372 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03373 S100027_03374 S100027_03374 S100027_03374 3209961 3210365 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the Cp-1 holin family gene gene3373 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03374 S100027_03375 S100027_03375 S100027_03375 3210518 3210955 - DNA protection during starvation protein Cytoplasm%3B Iron%3B Iron storage%3B Metal-binding%3B Oxidoreductase%3B Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions%2C which prevents hydroxyl radical production by the Fenton Fe(2+) ion (By similarity). It is capable of binding and sequestering Fe(2+) ion. Does not bind DNA%3B Belongs to the Dps family gene gene3374 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03375 S100027_03376 S100027_03376 S100027_03376 3211089 3211232 + hypothetical protein gene gene3375 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03376 S100027_03377 S100027_03377 S100027_03377 3211226 3211669 - uncharacterized protein gene gene3376 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03377 S100027_03378 S100027_03378 luxS luxS 3211801 3212274 - S-ribosylhomocysteine lyase Autoinducer synthesis%3B Iron%3B Lyase%3B Metal-binding%3B Quorum sensing%3B Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4%2C5- dihydroxy-2%2C3-pentadione (DPD)%3B Belongs to the LuxS family%3B KEGG: bsu:BSU30670 S-ribosylhomocysteine lyase gene gene3377 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03378 S100027_03379 S100027_03379 S100027_03379 3212412 3212639 + Putative membrane protein insertion efficiency factor Cell membrane%3B Membrane%3B Could be involved in insertion of integral membrane proteins into the membrane%3B Belongs to the UPF0161 family gene gene3378 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03379 S100027_03380 S100027_03380 S100027_03380 3212636 3213205 - Carbonate dehydratase Lyase%3B Metal-binding%3B Zinc%3B Reversible hydration of carbon dioxide%3B Belongs to the beta-class carbonic anhydrase family%3B KEGG: salv:SALWKB2_2139 carbonic anhydrase gene gene3379 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03380 S100027_03381 S100027_03381 S100027_03381 3213332 3214513 + COBW domain-containing protein ATP-binding%3B Coiled coil%3B Nucleotide-binding%3B Belongs to the SIMIBI class G3E GTPase family. CobW subfamily%3B Contains 1 cobW C-terminal domain gene gene3380 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03381 S100027_03382 S100027_03382 S100027_03382 3214612 3215643 + Zinc-binding protein AdcA Ion transport%3B Signal%3B Transport%3B Zinc%3B Zinc transport%3B Part of the ATP-driven transport system AdcABC for zinc. Belongs to the bacterial solute-binding protein 9 family gene gene3381 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03382 S100027_03383 S100027_03383 S100027_03383 3215729 3215974 - 50S ribosomal protein L31 type Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L31P family. Type B subfamily gene gene3382 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03383 S100027_03384 S100027_03384 cydA cydA 3216166 3217491 + Cytochrome bd ubiquinol oxidase subunit Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the cytochrome ubiquinol oxidase subunit 1 family%3B KEGG: gbm:Gbem_2016 cytochrome d ubiquinol oxidase subunit I%3B With oxygen as acceptor gene gene3383 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03384 S100027_03385 S100027_03385 cydB cydB 3217521 3218573 + Putative cytochrome bd menaquinol oxidase subunit II Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B May have a role in sporulation. Can compensate for the loss of cytochrome aa3%3B Belongs to the cytochrome ubiquinol oxidase subunit 2 family%3B KEGG: bld:BLi03216 cytochrome d ubiquinol oxidase subunit II%3B With oxygen as acceptor gene gene3384 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03385 S100027_03386 S100027_03386 S100027_03386 3218618 3218779 + uncharacterized protein gene gene3385 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03386 S100027_03387 S100027_03387 S100027_03387 3218806 3218997 + hypothetical protein gene gene3386 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03387 S100027_03388 S100027_03388 menC menC 3219156 3220265 - o-succinylbenzoate synthase Lyase%3B Magnesium%3B Menaquinone biosynthesis%3B Metal-binding%3B Converts 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)%3B Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily%3B KEGG: bli:BL02404 O-succinylbenzoate synthase gene gene3387 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03388 S100027_03389 S100027_03389 menE menE 3220278 3221714 - o-succinylbenzoate--CoA ligase ATP-binding%3B Ligase%3B Menaquinone biosynthesis%3B Nucleotide-binding%3B Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl- CoA (OSB-CoA)%3B Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily%3B KEGG: bli:BL02405 O-succinylbenzoic acid--CoA ligase gene gene3388 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03389 S100027_03390 S100027_03390 menB menB 3221792 3222610 - 1%2C4-dihydroxy-2-naphthoyl-CoA synthase Lyase%3B Menaquinone biosynthesis%3B Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1%2C4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)%3B Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily%3B KEGG: bst:GYO_3334 naphthoate synthase gene gene3389 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03390 S100027_03391 S100027_03391 S100027_03391 3222624 3223436 - 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate synthase Lyase%3B Menaquinone biosynthesis%3B Catalyzes a proton abstraction reaction that results in 2%2C5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate (SHCHC)%3B Belongs to the AB hydrolase superfamily. MenH family%3B KEGG: bsu:BSU30810 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate synthase gene gene3390 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03391 S100027_03392 S100027_03392 menD menD 3223433 3225175 - 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acidsynthase Magnesium%3B Manganese%3B Menaquinone biosynthesis%3B Metal-binding%3B Thiamine pyrophosphate%3B Transferase%3B Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)%3B Belongs to the TPP enzyme family. MenD subfamily%3B KEGG: bli:BL02408 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase gene gene3391 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03392 S100027_03393 S100027_03393 menF menF 3225172 3226596 - Isochorismate synthase Isomerase%3B Magnesium%3B Menaquinone biosynthesis%3B Metal-binding%3B Catalyzes the conversion of chorismate to isochorismate%3B Belongs to the isochorismate synthase family%3B KEGG: bsu:BSU30830 menaquinone-specific isochorismate synthase gene gene3392 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03393 S100027_03394 S100027_03394 menA menA 3226865 3227797 + 1%2C4-dihydroxy-2-naphthoate octaprenyltransferase Cell membrane%3B Membrane%3B Menaquinone biosynthesis%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Conversion of 1%2C4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK)%3B Belongs to the MenA family. Type 1 subfamily%3B KEGG: bli:BL01413 1%2C4-dihydroxy-2-naphthoate octaprenyltransferase%3B 1%2C4-dihydroxy-2-naphthoate polyprenyltransferase gene gene3393 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03394 S100027_03395 S100027_03395 S100027_03395 3227906 3228661 + uncharacterized protein Metal-binding%3B Zinc%3B Zinc-finger%3B Contains 1 dksA C4-type zinc finger gene gene3394 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03395 S100027_03396 S100027_03396 glgP glgP 3228695 3230152 - Glycogen phosphorylase Allosteric enzyme%3B Carbohydrate metabolism%3B Chloroplast%3B Glycosyltransferase%3B Plastid%3B Pyridoxal phosphate%3B Transferase%3B Transit peptide%3B Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However%2C all known phosphorylases share catalytic and structural properties (By similarity). May be not required for the degradation of starch%2C but the phosphorolysis of starch may play an important role in water stress tolerance%3B Belongs to the glycogen phosphorylase family%3B KEGG: eco:b3417 starch phosphorylase gene gene3395 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03396 S100027_03397 S100027_03397 S100027_03397 3230205 3231089 - Glycogen phosphorylase Allosteric enzyme%3B Carbohydrate metabolism%3B Glycogen metabolism%3B Glycosyltransferase%3B Pyridoxal phosphate%3B Transferase%3B Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However%2C all known phosphorylases share catalytic and structural properties (By similarity)%3B Belongs to the glycogen phosphorylase family%3B KEGG: blh:BaLi_c33000 starch phosphorylase gene gene3396 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03397 S100027_03398 S100027_03398 glgA glgA 3231050 3232531 - Starch synthase Glycogen biosynthesis%3B Glycosyltransferase%3B Transferase%3B Synthesizes alpha-1%2C4-glucan chains using ADP-glucose%3B Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily%3B KEGG: pat:Patl_0080 starch synthase gene gene3397 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03398 S100027_03399 S100027_03399 S100027_03399 3232528 3233556 - Glucose-1-phosphate adenylyltransferase ATP-binding%3B Carbohydrate metabolism%3B Glycogen biosynthesis%3B Glycogen metabolism%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase%3B Catalyzes the synthesis of ADP-glucose%2C a sugar donor used in elongation reactions on alpha-glucans%3B Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family%3B KEGG: bli:BL01417 glucose-1-phosphate adenylyltransferase gene gene3398 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03399 S100027_03400 S100027_03400 S100027_03400 3233583 3234722 - Glucose-1-phosphate adenylyltransferase ATP-binding%3B Carbohydrate metabolism%3B Glycogen biosynthesis%3B Glycogen metabolism%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase%3B Catalyzes the synthesis of ADP-glucose%2C a sugar donor used in elongation reactions on alpha-glucans%3B Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family%3B KEGG: bli:BL01418 glucose-1-phosphate adenylyltransferase gene gene3399 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03400 S100027_03401 S100027_03401 glgB glgB 3234719 3236602 - 1%2C4-alpha-glucan branching enzyme Carbohydrate metabolism%3B Glycogen biosynthesis%3B Glycogen metabolism%3B Glycosyltransferase%3B Transferase%3B Catalyzes the formation of the alpha-1%2C6-glucosidic linkages in glycogen by scission of a 1%2C4-alpha-linked oligosaccharide from growing alpha-1%2C4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1%2C6 position%3B Belongs to the glycosyl hydrolase 13 family. GlgB subfamily%3B KEGG: bli:BL01419 1%2C4-alpha-glucan branching enzyme gene gene3400 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03401 S100027_03402 S100027_03402 S100027_03402 3236786 3236860 - tRNA-Glu tRNA gene3401 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03402 S100027_03403 S100027_03403 S100027_03403 3236873 3236963 - tRNA-Ser tRNA gene3402 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03403 S100027_03404 S100027_03404 S100027_03404 3236965 3237039 - tRNA-Asn tRNA gene3403 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03404 S100027_03405 S100027_03405 S100027_03405 3237046 3237122 - tRNA-Ile tRNA gene3404 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03405 S100027_03406 S100027_03406 S100027_03406 3237135 3237208 - tRNA-Gly tRNA gene3405 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03406 S100027_03407 S100027_03407 S100027_03407 3237217 3237292 - tRNA-His tRNA gene3406 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03407 S100027_03408 S100027_03408 S100027_03408 3237315 3237390 - tRNA-Phe tRNA gene3407 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03408 S100027_03409 S100027_03409 S100027_03409 3237401 3237477 - tRNA-Asp tRNA gene3408 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03409 S100027_03410 S100027_03410 S100027_03410 3237523 3237599 - tRNA-Met tRNA gene3409 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03410 S100027_03411 S100027_03411 S100027_03411 3237624 3237716 - tRNA-Ser tRNA gene3410 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03411 S100027_03412 S100027_03412 S100027_03412 3237724 3237800 - tRNA-Met tRNA gene3411 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03412 S100027_03413 S100027_03413 S100027_03413 3237806 3237879 - tRNA-Met tRNA gene3412 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03413 S100027_03414 S100027_03414 S100027_03414 3237905 3237977 - tRNA-Ala tRNA gene3413 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03414 S100027_03415 S100027_03415 S100027_03415 3237984 3238060 - tRNA-Pro tRNA gene3414 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03415 S100027_03416 S100027_03416 S100027_03416 3238069 3238145 - tRNA-Arg tRNA gene3415 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03416 S100027_03417 S100027_03417 S100027_03417 3238156 3238227 - tRNA-Gly tRNA gene3416 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03417 S100027_03418 S100027_03418 S100027_03418 3238243 3238327 - tRNA-Leu tRNA gene3417 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03418 S100027_03419 S100027_03419 S100027_03419 3238334 3238409 - tRNA-Lys tRNA gene3418 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03419 S100027_03420 S100027_03420 S100027_03420 3238491 3238566 - tRNA-Thr tRNA gene3419 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03420 S100027_03421 S100027_03421 S100027_03421 3238582 3238657 - tRNA-Val tRNA gene3420 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03421 S100027_03422 S100027_03422 S100027_03422 3238853 3239059 - hypothetical protein gene gene3421 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03422 S100027_03423 S100027_03423 S100027_03423 3239384 3239499 - 5S ribosomal RNA rRNA gene3422 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03423 S100027_03424 S100027_03424 S100027_03424 3239631 3242561 - 23S ribosomal RNA rRNA gene3423 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03424 S100027_03425 S100027_03425 S100027_03425 3242733 3244283 - 16S ribosomal RNA rRNA gene3424 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03425 S100027_03426 S100027_03426 S100027_03426 3244910 3246010 - Arabinose metabolism transcriptional repressor Cytoplasm%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcriptional repressor of the arabinose utilization genes. Also regulates its own expression. Binds to two sequences within the promoters of the araABDLMNPQ-abfA operon and the araE gene%2C and to one sequence in the araR promoter. Contains 1 HTH gntR-type DNA-binding domain gene gene3425 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03426 S100027_03427 S100027_03427 S100027_03427 3246384 3246968 + Thiamine transporter ThiT Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably a thiamine-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane%2C not extracytoplasmic soluble proteins (By similarity)%3B Belongs to the ECF family. Thiamine transporter (TC 2. A. 88) subfamily gene gene3426 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03427 S100027_03428 S100027_03428 S100027_03428 3247009 3247566 - Sortase A Membrane%3B Transmembrane%3B Transmembrane helix%3B KEGG: blh:BaLi_c33300 sortase A gene gene3427 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03428 S100027_03429 S100027_03429 S100027_03429 3247673 3248668 - hypothetical protein gene gene3428 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03429 S100027_03430 S100027_03430 S100027_03430 3248849 3249037 + hypothetical protein gene gene3429 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03430 S100027_03431 S100027_03431 S100027_03431 3249163 3250275 + Response regulator aspartate phosphatase Hydrolase%3B Protein phosphatase%3B Repeat%3B TPR repeat%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bli:BL02513 response regulator aspartate phosphatase D%3B Acting on ester bonds gene gene3430 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03431 S100027_03432 S100027_03432 S100027_03432 3250277 3250405 + hypothetical protein gene gene3431 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03432 S100027_03433 S100027_03433 S100027_03433 3250485 3251132 + Pyroglutamyl-peptidase I Cytoplasm%3B Hydrolase%3B Protease%3B Thiol protease%3B Removes 5-oxoproline from various penultimate amino acid residues except L-proline. Belongs to the peptidase C15 family%3B KEGG: bsu:BSU02650 pyroglutamyl-peptidase gene gene3432 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03433 S100027_03434 S100027_03434 S100027_03434 3251251 3251907 + Ktr system potassium uptake protein Cell membrane%3B Ion transport%3B Membrane%3B NAD%3B Potassium%3B Potassium transport%3B Transport%3B Catalytic subunit of the KtrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress%3B Belongs to the KtrA potassium transport family%3B Contains 1 RCK C-terminal domain%3B Contains 1 RCK N-terminal domain gene gene3433 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03434 S100027_03435 S100027_03435 S100027_03435 3251910 3253229 + Ktr system potassium uptake protein Cell membrane%3B Ion transport%3B Membrane%3B Potassium%3B Potassium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Integral membrane subunit of the KtrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress%3B Belongs to the TrkH potassium transport family. Ktr (TC 2. A. 38. 4) subfamily gene gene3434 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03435 S100027_03436 S100027_03436 S100027_03436 3253240 3254154 - hypothetical protein gene gene3435 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03436 S100027_03437 S100027_03437 S100027_03437 3254278 3254760 + uncharacterized protein gene gene3436 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03437 S100027_03438 S100027_03438 S100027_03438 3254807 3255388 - Putative metal-sulfur cluster biosynthesis protein YuaD Contains 1 MOSC domain gene gene3437 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03438 S100027_03439 S100027_03439 gbsB gbsB 3255500 3256708 - Alcohol dehydrogenase Alternative initiation%3B NAD%3B Oxidoreductase%3B Essential for the utilization of choline as a precursor%3B Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: bsu:BSU31050 choline dehydrogenase gene gene3438 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03439 S100027_03440 S100027_03440 betB betB 3256726 3258198 - Betaine-aldehyde dehydrogenase NAD%3B Oxidoreductase%3B This is a soluble NAD-dependent betaine aldehyde- specific dehydrogenase. Essential for the utilization of choline as a precursor%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: bsu:BSU31060 betaine-aldehyde dehydrogenase gene gene3439 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03440 S100027_03441 S100027_03441 S100027_03441 3258522 3259076 + HTH-type transcriptional repressor GbsR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Negatively regulates the expression of the gbsAB and opuB operons. Required to control expression of these genes in response to choline availability. Also required to downregulate glycine betaine production once cellular adjustment to high osmolarity has been achieved%3B Belongs to the GbsR family gene gene3440 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03441 S100027_03442 S100027_03442 S100027_03442 3259196 3260824 + High-affinity choline transporter Glycoprotein%3B Ion transport%3B Membrane%3B Neurotransmitter biosynthesis%3B Sodium%3B Sodium transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Imports choline from the extracellular space to the neuron with high affinity. Rate-limiting step in acetylcholine synthesis. Sodium ion and chloride ion dependent (By similarity)%3B Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene3441 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03442 S100027_03443 S100027_03443 S100027_03443 3260868 3261785 - Putative S-adenosyl-L-methionine-dependent methyltransferase YktD Methyltransferase%3B Transferase%3B May be involved in polyketide synthesis. Belongs to the UPF0677 family gene gene3442 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03443 S100027_03444 S100027_03444 S100027_03444 3261960 3263141 - Alanine racemase Isomerase%3B Pyridoxal phosphate%3B Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids%3B Belongs to the alanine racemase family%3B KEGG: bsu:BSU17640 alanine racemase gene gene3443 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03444 S100027_03445 S100027_03445 oxdD oxdD 3263456 3264637 + Oxalate decarboxylase Cytoplasm%3B Decarboxylase%3B Lyase%3B Manganese%3B Metal-binding%3B Converts oxalate to formate and CO(2). To B. subtilis OxdC%3B KEGG: bsm:BSM4216_3794 oxalate decarboxylase gene gene3444 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03445 S100027_03446 S100027_03446 S100027_03446 3265177 3265698 + hypothetical protein gene gene3445 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03446 S100027_03447 S100027_03447 S100027_03447 3265706 3266665 + hypothetical protein gene gene3446 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03447 S100027_03448 S100027_03448 S100027_03448 3267086 3267661 - N-acetylmuramoyl-L-alanine amidase Cell wall biogenesis/degradation%3B Hydrolase%3B Repeat%3B Secreted%3B Signal%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B KEGG: bli:BL01582 N-acetylmuramoyl-L-alanine amidase gene gene3447 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03448 S100027_03449 S100027_03449 S100027_03449 3267887 3268069 + hypothetical protein gene gene3448 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03449 S100027_03450 S100027_03450 S100027_03450 3268129 3268201 - tRNA-Ala tRNA gene3449 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03450 S100027_03451 S100027_03451 S100027_03451 3268439 3268837 - hypothetical protein gene gene3450 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03451 S100027_03452 S100027_03452 S100027_03452 3268852 3270774 - hypothetical protein gene gene3451 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03452 S100027_03453 S100027_03453 S100027_03453 3270794 3271117 - hypothetical protein gene gene3452 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03453 S100027_03454 S100027_03454 S100027_03454 3271114 3271821 - hypothetical protein gene gene3453 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03454 S100027_03455 S100027_03455 S100027_03455 3271839 3272189 - hypothetical protein gene gene3454 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03455 S100027_03456 S100027_03456 S100027_03456 3272208 3272567 - hypothetical protein gene gene3455 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03456 S100027_03457 S100027_03457 S100027_03457 3272861 3273070 + uncharacterized protein gene gene3456 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03457 S100027_03458 S100027_03458 S100027_03458 3273093 3273266 + hypothetical protein gene gene3457 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03458 S100027_03459 S100027_03459 S100027_03459 3273287 3274768 - hypothetical protein gene gene3458 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03459 S100027_03460 S100027_03460 S100027_03460 3274785 3275918 - 1%2C2-diacylglycerol 3-glucosyltransferase Glycosyltransferase%3B Transferase%3B Belongs to the glycosyltransferase 28 family%3B KEGG: pjd:Pjdr2_5001 processive 1%2C2-diacylglycerol beta-glucosyltransferase gene gene3459 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03460 S100027_03461 S100027_03461 S100027_03461 3276018 3276566 + uncharacterized protein gene gene3460 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03461 S100027_03462 S100027_03462 S100027_03462 3276611 3277426 - putative metallophosphoesterase YkoQ Hydrolase%3B Metal-binding%3B Belongs to the metallophosphoesterase superfamily gene gene3461 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03462 S100027_03463 S100027_03463 S100027_03463 3277558 3278388 - Undecaprenyl-diphosphate phosphatase Antibiotic resistance%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Membrane%3B Peptidoglycan synthesis%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin%3B Belongs to the UppP family%3B KEGG: bli:BL02576 undecaprenyl-diphosphatase gene gene3462 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03463 S100027_03464 S100027_03464 S100027_03464 3278466 3279611 - UPF0118 membrane protein YubA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0118 (PerM) family gene gene3463 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03464 S100027_03465 S100027_03465 S100027_03465 3279826 3280809 + D-xylose 1-dehydrogenase (NADP(+)) NADP%3B Oxidoreductase%3B Plasmid%3B Secreted%3B Signal%3B NADP-dependent D-xylose dehydrogenase involved in the degradation of D-xylose%2C a major component of hemicelluloses such as xylan. Even if it shows D-xylose dehydrogenase activity%2C it is not essential for D-xylose degradation%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: lsa:LSA1535 null%3B Oxidoreductases gene gene3464 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03465 S100027_03466 S100027_03466 S100027_03466 3280854 3281378 - uncharacterized protein Belongs to the peptidase C56 family%3B Contains 1 PfpI endopeptidase domain%3B KEGG: dsa:Desal_2750 protease I%3B Glycosylases gene gene3465 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03466 S100027_03467 S100027_03467 S100027_03467 3281511 3283493 - Methyl-accepting chemotaxis protein McpB Cell membrane%3B Chemotaxis%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpB is required for taxis towards asparagine%2C aspartate%2C glutamine%2C and histidine%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene3466 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03467 S100027_03468 S100027_03468 S100027_03468 3283627 3285612 - Methyl-accepting chemotaxis protein McpA Cell membrane%3B Chemotaxis%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpA is required for taxis towards glucose and alpha-methylglucoside%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene3467 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03468 S100027_03469 S100027_03469 S100027_03469 3285758 3286942 - Methyl-accepting chemotaxis protein McpA Cell membrane%3B Chemotaxis%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpA is required for taxis towards glucose and alpha-methylglucoside%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene3468 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03469 S100027_03470 S100027_03470 S100027_03470 3286923 3287735 - Methyl-accepting chemotaxis protein McpB Cell membrane%3B Chemotaxis%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpB is required for taxis towards asparagine%2C aspartate%2C glutamine%2C and histidine%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene3469 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03470 S100027_03471 S100027_03471 S100027_03471 3287857 3288603 + Protein-glutamine gamma-glutamyltransferase Acyltransferase%3B Sporulation%3B Transferase%3B Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links%3B Belongs to the bacillus TGase family%3B KEGG: blh:BaLi_c33790 protein-glutamine gamma-glutamyltransferase gene gene3470 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03471 S100027_03472 S100027_03472 ncd2 ncd2 3288583 3289638 - Nitronate monooxygenase Flavoprotein%3B FMN%3B Monooxygenase%3B Oxidoreductase%3B Catalyzes the oxidation of alkyl nitronates to produce the corresponding carbonyl compounds and nitrites%3B Belongs to the nitronate monooxygenase family%3B KEGG: bli:BL02583 nitronate monooxygenase gene gene3471 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03472 S100027_03473 S100027_03473 S100027_03473 3289654 3290055 - Nitronate monooxygenase Belongs to the UPF0047 family%3B KEGG: bao:BAMF_2926 nitronate monooxygenase gene gene3472 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03473 S100027_03474 S100027_03474 S100027_03474 3290094 3291776 - Alpha-glucosidase Cytoplasm%3B Glycosidase%3B Hydrolase%3B Belongs to the glycosyl hydrolase 13 family%3B KEGG: aza:AZKH_2678 alpha-glucosidase gene gene3473 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03474 S100027_03475 S100027_03475 S100027_03475 3292079 3292669 + hypothetical protein gene gene3474 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03475 S100027_03476 S100027_03476 S100027_03476 3292666 3293340 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3475 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03476 S100027_03477 S100027_03477 S100027_03477 3293423 3294208 - Xyloglucan-specific endo-beta-1%2C4-glucanase Carbohydrate metabolism%3B Cellulose degradation%3B Glycosidase%3B Hydrolase%3B Polysaccharide degradation%3B Signal%3B Belongs to the glycosyl hydrolase 12 (cellulase H) family%3B KEGG: tre:TRIREDRAFT_123232 xyloglucan-specific endo-beta-1%2C4-glucanase gene gene3476 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03477 S100027_03478 S100027_03478 S100027_03478 3294389 3295678 - UPF0053 protein YhdP CBS domain%3B Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0053 family%3B Contains 2 CBS domains%3B Contains 1 DUF21 domain gene gene3477 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03478 S100027_03479 S100027_03479 S100027_03479 3295729 3296409 - Putative membrane protease YugP Cell membrane%3B Hydrolase%3B Membrane%3B Metal-binding%3B Metalloprotease%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Zinc. gene gene3478 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03479 S100027_03480 S100027_03480 S100027_03480 3296503 3296679 - hypothetical protein gene gene3479 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03480 S100027_03481 S100027_03481 S100027_03481 3296877 3297164 + Protein mistic Cell membrane%3B Chaperone%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Chaperone that facilitates the production and integration of integral membrane proteins into the bacterial lipid bilayer gene gene3480 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03481 S100027_03482 S100027_03482 S100027_03482 3297161 3298144 + Putative potassium channel protein YugO Cell membrane%3B Ion channel%3B Ion transport%3B Membrane%3B Potassium%3B Potassium channel%3B Potassium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Contains 1 RCK N-terminal domain gene gene3481 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03482 S100027_03483 S100027_03483 S100027_03483 3298141 3298545 - uncharacterized protein gene gene3482 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03483 S100027_03484 S100027_03484 S100027_03484 3298687 3299148 - UPF0702 transmembrane protein YdfR Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0702 family gene gene3483 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03484 S100027_03485 S100027_03485 S100027_03485 3299266 3299742 + putative membrane protein YtaB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the TspO/BZRP family gene gene3484 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03485 S100027_03486 S100027_03486 S100027_03486 3299811 3300335 + Ribosomal-protein-alanine N-acetyltransferase Acyltransferase%3B Transferase%3B Contains 1 N-acetyltransferase domain%3B KEGG: bha:BH0837 ribosomal-protein-alanine N-acetyltransferase gene gene3485 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03486 S100027_03487 S100027_03487 S100027_03487 3300668 3301351 + hypothetical protein gene gene3486 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03487 S100027_03488 S100027_03488 S100027_03488 3301453 3301821 + SPBc2 prophage-derived uncharacterized protein YolD gene gene3487 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03488 S100027_03489 S100027_03489 S100027_03489 3301846 3302076 - hypothetical protein gene gene3488 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03489 S100027_03490 S100027_03490 S100027_03490 3302331 3302474 - hypothetical protein gene gene3489 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03490 S100027_03491 S100027_03491 S100027_03491 3302650 3303102 + hypothetical protein gene gene3490 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03491 S100027_03492 S100027_03492 S100027_03492 3303099 3303503 + hypothetical protein gene gene3491 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03492 S100027_03493 S100027_03493 S100027_03493 3303505 3303702 - putative 10.3 kDa protein in GP2-GP6 intergenic region gene gene3492 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03493 S100027_03494 S100027_03494 S100027_03494 3303999 3305498 + Ribonuclease YxiD Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene3493 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03494 S100027_03495 S100027_03495 S100027_03495 3305513 3305911 + hypothetical protein gene gene3494 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03495 S100027_03496 S100027_03496 S100027_03496 3305957 3307036 - N-acetylmuramoyl-L-alanine amidase Cell wall biogenesis/degradation%3B Hydrolase%3B Repeat%3B Secreted%3B Signal%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B KEGG: bli:BL01582 N-acetylmuramoyl-L-alanine amidase gene gene3495 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03496 S100027_03497 S100027_03497 S100027_03497 3307088 3307351 - SPBc2 prophage-derived protein BhlB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B May be involved in the secretion of the autolysin BlyA. Belongs to the SPP1 holin family gene gene3496 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03497 S100027_03498 S100027_03498 S100027_03498 3307367 3307636 - putative 11.0 kDa protein in cwlL 5'region To B. licheniformis xpaL1 and to B. subtilis XhlA gene gene3497 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03498 S100027_03499 S100027_03499 S100027_03499 3307699 3307881 - hypothetical protein gene gene3498 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03499 S100027_03500 S100027_03500 S100027_03500 3307878 3308201 - SPBc2 prophage-derived uncharacterized protein YomQ gene gene3499 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03500 S100027_03501 S100027_03501 S100027_03501 3308214 3309563 - uncharacterized protein To B. subtilis XkdV gene gene3500 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03501 S100027_03502 S100027_03502 S100027_03502 3309577 3312222 - Putative phage-related protein YobO Repeat%3B Contains 6 PbH1 repeats gene gene3501 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03502 S100027_03503 S100027_03503 S100027_03503 3312259 3313971 - N-acetylmuramoyl-L-alanine amidase Cell wall%3B Cell wall biogenesis/degradation%3B Glycosidase%3B Hydrolase%3B Magnesium%3B Secreted%3B Signal%3B Is the major glucosaminidase responsible for peptidoglycan structural determination during vegetative growth. Acts processively from the ends of the glycan strands. Also plays a role in motility%2C chemotaxis and cell division%3B Belongs to the glycosyl hydrolase 73 family%3B KEGG: smu:SMU_76 N-acetylmuramoyl-L-alanine amidase gene gene3502 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03503 S100027_03504 S100027_03504 S100027_03504 3313984 3314613 - hypothetical protein gene gene3503 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03504 S100027_03505 S100027_03505 S100027_03505 3314819 3319288 - Tape measure protein Host membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Viral tail assembly%3B Virus exit from host cell%3B Plays a role in virion tail formation. The length of the tape measure protein is proportional to the length of the phage's tail gene gene3504 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03505 S100027_03506 S100027_03506 S100027_03506 3319351 3319449 - hypothetical protein gene gene3505 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03506 S100027_03507 S100027_03507 S100027_03507 3319497 3319862 - hypothetical protein gene gene3506 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03507 S100027_03508 S100027_03508 S100027_03508 3319916 3320533 - hypothetical protein gene gene3507 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03508 S100027_03509 S100027_03509 S100027_03509 3320548 3320931 - hypothetical protein gene gene3508 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03509 S100027_03510 S100027_03510 S100027_03510 3320928 3321326 - hypothetical protein gene gene3509 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03510 S100027_03511 S100027_03511 S100027_03511 3321326 3321634 - hypothetical protein gene gene3510 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03511 S100027_03512 S100027_03512 S100027_03512 3321624 3321926 - hypothetical protein gene gene3511 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03512 S100027_03513 S100027_03513 S100027_03513 3321947 3322372 - Collagen alpha chain Alternative splicing%3B Cell membrane%3B Coiled coil%3B Collagen%3B Membrane%3B Repeat%3B Signal-anchor%3B Transmembrane%3B Transmembrane helix%3B Contains 7 collagen-like domains gene gene3512 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03513 S100027_03514 S100027_03514 S100027_03514 3322395 3323705 - hypothetical protein gene gene3513 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03514 S100027_03515 S100027_03515 S100027_03515 3323745 3324476 - Endopeptidase Clp Cytoplasm%3B Hydrolase%3B Protease%3B Serine protease%3B Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins%3B Belongs to the peptidase S14 family%3B KEGG: cba:CLB_2447 ATP-dependent Clp protease%2C protease subunit gene gene3514 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03515 S100027_03516 S100027_03516 S100027_03516 3324421 3325731 - hypothetical protein gene gene3515 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03516 S100027_03517 S100027_03517 S100027_03517 3325732 3325926 - hypothetical protein gene gene3516 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03517 S100027_03518 S100027_03518 S100027_03518 3325936 3327645 - Putative terminase large subunit Viral genome packaging%3B Virus exit from host cell%3B Belongs to the phage terminase family gene gene3517 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03518 S100027_03519 S100027_03519 S100027_03519 3327642 3328157 - hypothetical protein gene gene3518 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03519 S100027_03520 S100027_03520 S100027_03520 3328388 3328762 - hypothetical protein gene gene3519 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03520 S100027_03521 S100027_03521 S100027_03521 3328789 3329097 - hypothetical protein gene gene3520 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03521 S100027_03522 S100027_03522 S100027_03522 3329312 3329536 - Spore coat protein Sporulation. gene gene3521 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03522 S100027_03523 S100027_03523 S100027_03523 3330275 3330655 - hypothetical protein gene gene3522 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03523 S100027_03524 S100027_03524 S100027_03524 3331030 3331854 + hypothetical protein gene gene3523 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03524 S100027_03525 S100027_03525 S100027_03525 3331938 3332141 - hypothetical protein gene gene3524 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03525 S100027_03526 S100027_03526 S100027_03526 3332256 3332777 - hypothetical protein gene gene3525 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03526 S100027_03527 S100027_03527 S100027_03527 3332774 3332944 - hypothetical protein gene gene3526 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03527 S100027_03528 S100027_03528 S100027_03528 3332941 3333480 - hypothetical protein gene gene3527 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03528 S100027_03529 S100027_03529 S100027_03529 3333477 3333914 - hypothetical protein gene gene3528 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03529 S100027_03530 S100027_03530 S100027_03530 3334183 3336621 - Putative helicase L207/L206 ATP-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Contains 1 SF3 helicase domain gene gene3529 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03530 S100027_03531 S100027_03531 S100027_03531 3336682 3337122 - hypothetical protein gene gene3530 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03531 S100027_03532 S100027_03532 S100027_03532 3337122 3338054 - hypothetical protein gene gene3531 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03532 S100027_03533 S100027_03533 S100027_03533 3338058 3338615 - hypothetical protein gene gene3532 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03533 S100027_03534 S100027_03534 S100027_03534 3338708 3338974 - hypothetical protein gene gene3533 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03534 S100027_03535 S100027_03535 S100027_03535 3338931 3339047 - hypothetical protein gene gene3534 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03535 S100027_03536 S100027_03536 S100027_03536 3339044 3339310 - hypothetical protein gene gene3535 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03536 S100027_03537 S100027_03537 S100027_03537 3339434 3339703 - hypothetical protein gene gene3536 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03537 S100027_03538 S100027_03538 S100027_03538 3339709 3339894 - hypothetical protein gene gene3537 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03538 S100027_03539 S100027_03539 S100027_03539 3340163 3340591 + hypothetical protein gene gene3538 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03539 S100027_03540 S100027_03540 S100027_03540 3340600 3341022 + putative immunity region protein gene gene3539 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03540 S100027_03541 S100027_03541 S100027_03541 3341067 3342215 + ICEBs1 integrase DNA integration%3B DNA recombination%3B DNA-binding%3B Viral genome integration%3B Virus entry into host cell%3B Putative integrase that is involved in the insertion of the integrative and conjugative element ICEBs1. Required for the excision of ICEBs1 from the donor cell genome and subsequent integration in the recipient cell genome. Appears not to be transferred through the mating pore. Integration of ICEBs1 involves an attachment site in the chromosome%2C attB%2C and a site in the circular form of ICEBs1%2C attICEBs1%3B Belongs to the 'phage' integrase family gene gene3540 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03541 S100027_03542 S100027_03542 S100027_03542 3342299 3343651 - Glucose-6-phosphate isomerase Cytoplasm%3B Gluconeogenesis%3B Glycolysis%3B Isomerase%3B Phosphoprotein%3B Belongs to the GPI family%3B KEGG: bsu:BSU31350 glucose-6-phosphate isomerase gene gene3541 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03542 S100027_03543 S100027_03543 S100027_03543 3343941 3345104 - putative NADH-dependent butanol dehydrogenase NAD%3B Oxidoreductase%3B Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: bsu:BSU31370 null%3B With NAD(+) or NADP(+) as acceptor gene gene3542 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03543 S100027_03544 S100027_03544 S100027_03544 3345247 3345483 + putative membrane protein YuzA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3543 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03544 S100027_03545 S100027_03545 S100027_03545 3345716 3346105 - General stress protein Cytoplasm%3B Stress response%3B Contains 1 S1 motif domain gene gene3544 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03545 S100027_03546 S100027_03546 S100027_03546 3346309 3347481 - Putative aminotransferase YugH Amino-acid biosynthesis%3B Aminotransferase%3B Cytoplasm%3B Pyridoxal phosphate%3B Transferase%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bli:BL02594 aminotransferase%3B Transaminases gene gene3545 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03546 S100027_03547 S100027_03547 S100027_03547 3347482 3347982 - putative HTH-type transcriptional regulator YugG DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH asnC-type DNA-binding domain gene gene3546 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03547 S100027_03548 S100027_03548 dhaA dhaA 3348187 3349008 + Haloalkane dehalogenase Hydrolase%3B Serine esterase%3B Belongs to the DmpD/TodF/XylF esterase family%3B KEGG: hme:HFX_2390 haloalkane dehalogenase gene gene3547 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03548 S100027_03549 S100027_03549 S100027_03549 3349048 3349302 - uncharacterized protein gene gene3548 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03549 S100027_03550 S100027_03550 S100027_03550 3349382 3349879 - hypothetical protein gene gene3549 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03550 S100027_03551 S100027_03551 patB patB 3349986 3351149 + Cystathionine beta-lyase Amino-acid biosynthesis%3B Lyase%3B Methionine biosynthesis%3B Pyridoxal phosphate%3B Catalyzes the transformation of cystathionine to homocysteine. Also exhibits cysteine desulfhydrase activity in vitro%2C producing sulfide from cysteine. Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. MalY/PatB cystathionine beta-lyase subfamily%3B KEGG: bli:BL02532 cystathione beta-lyase gene gene3550 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03551 S100027_03552 S100027_03552 S100027_03552 3351176 3351376 - hypothetical protein gene gene3551 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03552 S100027_03553 S100027_03553 S100027_03553 3351444 3351833 + Kinase-associated lipoprotein Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal. gene gene3552 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03553 S100027_03554 S100027_03554 S100027_03554 3351861 3352478 - putative 3'-5' exonuclease KapD Exonuclease%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nuclease%3B Sporulation%3B Specifically inhibits the KinA pathway to sporulation%3B Contains 1 exonuclease domain gene gene3553 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03554 S100027_03555 S100027_03555 S100027_03555 3352697 3353965 + Multi-drug resistance efflux pump PmrA like protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Efflux pump for various substrates%3B Belongs to the major facilitator superfamily. TCR/Tet family gene gene3554 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03555 S100027_03556 S100027_03556 S100027_03556 3354099 3355934 + Penicillin-binding protein Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Peptidoglycan synthesis%3B Signal%3B In the N-terminal sectio%3B belongs to the glycosyltransferase 51 family%3B In the C-terminal sectio%3B belongs to the transpeptidase family gene gene3555 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03556 S100027_03557 S100027_03557 nagA nagA 3355958 3356365 + Alpha-N-acetylgalactosaminidase Belongs to the DCC thiol-disulfide oxidoreductase family%3B KEGG: dfa:DFA_08734 alpha-N-acetylgalactosaminidase gene gene3556 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03557 S100027_03558 S100027_03558 S100027_03558 3356416 3356973 - putative membrane protein YufK Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3557 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03558 S100027_03559 S100027_03559 yufL yufL 3357160 3358761 + Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of a two-component regulatory system MalK/MalR. Involved in the activation of maeA%2C maeN and yflS in presence of malate. Probably activates MalR by phosphorylation%3B Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bsu:BSU31520 two-component system%2C CitB family%2C sensor histidine kinase MalK gene gene3558 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03559 S100027_03560 S100027_03560 S100027_03560 3358754 3359461 + Chemotaxis response regulator protein-glutamate methylesterase Chemotaxis%3B Cytoplasm%3B Hydrolase%3B Phosphoprotein%3B Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene3559 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03560 S100027_03561 S100027_03561 cho1 cho1 3360016 3360552 + CDP-diacylglycerol--serine O-phosphatidyltransferase Cell membrane%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Belongs to the CDP-alcohol phosphatidyltransferase class-I family%3B KEGG: bli:BL02540 CDP-diacylglycerol---serine O-phosphatidyltransferase gene gene3560 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03561 S100027_03562 S100027_03562 S100027_03562 3360559 3361041 + putative membrane protein YbfM Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the DedA family gene gene3561 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03562 S100027_03563 S100027_03563 pisD pisD 3361084 3361875 + Phosphatidylserine decarboxylase Decarboxylase%3B Lipid biosynthesis%3B Lipid metabolism%3B Lyase%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Pyruvate%3B Zymogen%3B Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily%3B KEGG: bli:BL02542 phosphatidylserine decarboxylase gene gene3562 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03563 S100027_03564 S100027_03564 S100027_03564 3362147 3363490 + Na(+)-malate symporter Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Acts as a Na(+)-malate symporter%2C as it catalyzes malate-dependent uptake of Na(+) and Na(+)-dependent uptake of malate%3B Belongs to the sodium:citrate (SCF) symporter family gene gene3563 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03564 S100027_03565 S100027_03565 S100027_03565 3363550 3363783 - hypothetical protein gene gene3564 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03565 S100027_03566 S100027_03566 S100027_03566 3364029 3366431 + Na(+)/H(+) antiporter subunit A1 Antiport%3B Cell membrane%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion%3B Belongs to the CPA3 antiporters (TC 2. A. 63) subunit A family gene gene3565 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03566 S100027_03567 S100027_03567 S100027_03567 3366428 3366859 + Na(+)/H(+) antiporter subunit Antiport%3B Cell membrane%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mnh complex is a Na(+)Li(+)/H(+) antiporter involved in Na(+) and/or Li(+) excretion and Na(+) resistance. Na(+)/H(+) antiport consumes a transmembrane electrical potential%2C and is thus inferred to be electrogenic. Does not transport K(+)%2C Ca(2+) or Mg(2+). Belongs to the CPA3 antiporters (TC 2. A. 63) subunit B family gene gene3566 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03567 S100027_03568 S100027_03568 S100027_03568 3366859 3367200 + Na(+)/H(+) antiporter subunit C1 Antiport%3B Cell membrane%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion%3B Belongs to the CPA3 antiporters (TC 2. A. 63) subunit C family gene gene3567 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03568 S100027_03569 S100027_03569 S100027_03569 3367184 3368671 + Putative antiporter subunit mnhD2 Antiport%3B Cell membrane%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the CPA3 antiporters (TC 2. A. 63) subunit D family gene gene3568 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03569 S100027_03570 S100027_03570 S100027_03570 3368677 3369153 + Na(+)/H(+) antiporter subunit E1 Antiport%3B Cell membrane%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion%3B Belongs to the CPA3 antiporters (TC 2. A. 63) subunit E family gene gene3569 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03570 S100027_03571 S100027_03571 S100027_03571 3369153 3369437 + Na(+)/H(+) antiporter subunit Antiport%3B Cell membrane%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B. subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter%2C although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+)%2C Ca(2+) or Mg(2+). Involved in cholate and Na(+) efflux activities%2C which may be mechanistically coupled. Does not require other Mrp proteins for its own function. Belongs to the CPA3 antiporters (TC 2. A. 63) subunit F family%3B overlaps another CDS with the same product name gene gene3570 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03571 S100027_03572 S100027_03572 S100027_03572 3369421 3369795 + Na(+)/H(+) antiporter subunit Antiport%3B Cell membrane%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B May enhance MrpA stability%2C assembly%2C or function. May play chaperone or assembly roles for MrpA and perhaps for other mrp proteins. Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B. subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter%2C although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+)%2C Ca(2+) or Mg(2+). Belongs to the CPA3 antiporters (TC 2. A. 63) subunit G family%3B overlaps another CDS with the same product name gene gene3571 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03572 S100027_03573 S100027_03573 menI menI 3369835 3370227 - 1%2C4-dihydroxy-2-naphthoyl-CoA hydrolase Hydrolase%3B Is not required for competence. Belongs to the thioesterase PaaI family%3B KEGG: eal:EAKF1_ch4366 1%2C4-dihydroxy-2-naphthoyl-CoA hydrolase gene gene3572 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03573 S100027_03574 S100027_03574 S100027_03574 3370241 3370879 - Transcriptional regulatory protein ComA Activator%3B Competence%3B Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Response regulator in the two-component regulatory system ComP/ComA involved in a major quorum response pathway that regulates the development of genetic competence. Regulates directly the expression of over 20 genes%2C including genes of the srfA operon%2C degQ%2C rapA%2C rapC%2C rapE%2C rapF%2C etc. Regulates indirectly%2C through the regulation of comK transcription%2C the expression of late competence genes%3B Contains 1 HTH luxR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3573 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03574 S100027_03575 S100027_03575 comP comP 3370966 3373266 - Histidine kinase ATP-binding%3B Cell membrane%3B Competence%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Sporulation%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Sensor in the two-component regulatory system ComP/ComA involved in a major quorum response pathway that regulates the development of genetic competence. Plays a role in sporulation%2C at least partly interchangeable with that of SpoIIJ. Probably activates ComA by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bao:BAMF_2968 two-component system%2C NarL family%2C sensor histidine kinase ComP gene gene3574 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03575 S100027_03576 S100027_03576 S100027_03576 3373268 3373441 - hypothetical protein gene gene3575 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03576 S100027_03577 S100027_03577 S100027_03577 3373445 3374326 - Competence regulatory protein ComQ Cell membrane%3B Competence%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Involved in the maturation of ComX%2C part of a major quorum-sensing system that regulates the development of genetic competence gene gene3576 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03577 S100027_03578 S100027_03578 S100027_03578 3374515 3374655 - Degradation enzyme regulation protein DegQ Stimulates the phosphotransfer from phospho-DegS to DegU. Affects protease and levansucrose production (By similarity)%3B Belongs to the DegQ family gene gene3577 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03578 S100027_03579 S100027_03579 S100027_03579 3374933 3375148 - hypothetical protein gene gene3578 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03579 S100027_03580 S100027_03580 S100027_03580 3375150 3375488 + uncharacterized protein gene gene3579 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03580 S100027_03581 S100027_03581 S100027_03581 3375531 3376751 - uncharacterized protein Contains 1 EAL domain gene gene3580 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03581 S100027_03582 S100027_03582 pncB pncB 3376930 3378399 - Nicotinate phosphoribosyltransferase Ligase%3B Pyridine nucleotide biosynthesis%3B Transferase%3B Catalyzes the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN)%3B Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP%3B Belongs to the NAPRTase family%3B KEGG: bli:BL02611 nicotinate phosphoribosyltransferase gene gene3581 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03582 S100027_03583 S100027_03583 S100027_03583 3378417 3378968 - putative isochorismatase family protein PncA Hydrolase%3B Belongs to the isochorismatase family gene gene3582 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03583 S100027_03584 S100027_03584 S100027_03584 3379153 3379554 - uncharacterized protein gene gene3583 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03584 S100027_03585 S100027_03585 S100027_03585 3379649 3379897 - uncharacterized protein gene gene3584 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03585 S100027_03586 S100027_03586 S100027_03586 3379971 3380192 - Spore germination protein-like protein YueG Belongs to the GerPA/GerPF family gene gene3585 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03586 S100027_03587 S100027_03587 S100027_03587 3380249 3381358 - UPF0118 membrane protein YueF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0118 (PerM) family gene gene3586 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03587 S100027_03588 S100027_03588 S100027_03588 3381547 3381981 + Putative HTH-type transcriptional regulator YwnA DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH rrf2-type DNA-binding domain gene gene3587 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03588 S100027_03589 S100027_03589 S100027_03589 3382235 3383047 + hypothetical protein gene gene3588 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03589 S100027_03590 S100027_03590 S100027_03590 3383194 3384657 + hypothetical protein gene gene3589 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03590 S100027_03591 S100027_03591 S100027_03591 3384654 3385184 - Putative phosphohydrolase YueE Hydrolase%3B Contains 1 HD domain gene gene3590 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03591 S100027_03592 S100027_03592 yueD yueD 3385321 3386052 - Benzil reductase ((S)-benzoin forming) Cytoplasm%3B NADP%3B Oxidoreductase%3B Reduces benzil stereospecifically to (S)-benzoin%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bli:BL02617 benzil reductase ((S)-benzoin forming) gene gene3591 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03592 S100027_03593 S100027_03593 S100027_03593 3386199 3386687 - hypothetical protein gene gene3592 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03593 S100027_03594 S100027_03594 S100027_03594 3386677 3389739 - Bacteriophage SPP1 adsorption protein YueB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Bacteriophage SPP1 receptor. Essential for the irreversible adsorption of the bacteriophage gene gene3593 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03594 S100027_03595 S100027_03595 S100027_03595 3389736 3394220 - Ftsk domain-containing protein YukB ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Contains 2 FtsK domains gene gene3594 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03595 S100027_03596 S100027_03596 S100027_03596 3394257 3395573 - uncharacterized protein Cell membrane%3B Coiled coil%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the EssB family gene gene3595 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03596 S100027_03597 S100027_03597 S100027_03597 3395588 3395827 - putative ubiquitin-like protein YukD gene gene3596 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03597 S100027_03598 S100027_03598 S100027_03598 3395908 3396204 - Virulence factor EsxA Secreted%3B Virulence%3B Virulence factor that is important for the establishment of infection in the host%3B Belongs to the ESAT-6 (esx) family gene gene3597 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03598 S100027_03599 S100027_03599 S100027_03599 3396537 3397946 - Sodium/alanine symporter AgcS Amino-acid transport%3B Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably functions as a sodium/L- and D-alanine symporter for alanine uptake%3B Belongs to the sodium:alanine (SAF) symporter family gene gene3598 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03599 S100027_03600 S100027_03600 S100027_03600 3398129 3399367 + Transcriptional activator AdeR Activator%3B DNA-binding%3B Sporulation%3B Transcription%3B Transcription regulation%3B Mediates ald expression in response to alanine availability and is important for normal sporulation in B. subtilis%3B Belongs to the CdaR family gene gene3599 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03600 S100027_03601 S100027_03601 pntA pntA 3399478 3400617 + NAD(P)(+) transhydrogenase (Re/Si-specific) NAD%3B Oxidoreductase%3B May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer%3B Belongs to the AlaDH/PNT family%3B KEGG: eco:b1603 NAD(P) transhydrogenase subunit alpha gene gene3600 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03601 S100027_03602 S100027_03602 S100027_03602 3400668 3400913 - hypothetical protein gene gene3601 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03602 S100027_03603 S100027_03603 yedY yedY 3400928 3401521 - putative oxidoreductase YuiH Metal-binding%3B Molybdenum%3B Oxidoreductase%3B KEGG: bli:BL05322 sulfoxide reductase catalytic subunit YedY%3B Acting on a sulfur group of donors gene gene3602 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03603 S100027_03604 S100027_03604 S100027_03604 3401624 3402220 + Putative biotin transporter BioYB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Putative biotin transporter%3B Belongs to the BioY family gene gene3603 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03604 S100027_03605 S100027_03605 S100027_03605 3402301 3403629 - Putative amino acid transporter YuiF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport. gene gene3604 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03605 S100027_03606 S100027_03606 carP carP 3403781 3405271 - Leucyl aminopeptidase Aminopeptidase%3B Cytoplasm%3B Hydrolase%3B Manganese%3B Metal-binding%3B Protease%3B Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides%3B Belongs to the peptidase M17 family%3B KEGG: bli:BL05323 leucyl aminopeptidase gene gene3605 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03606 S100027_03607 S100027_03607 S100027_03607 3405437 3405913 + putative membrane protein YuiD Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3606 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03607 S100027_03608 S100027_03608 S100027_03608 3405956 3406630 - uncharacterized protein Signal. gene gene3607 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03608 S100027_03609 S100027_03609 S100027_03609 3406756 3407085 - putative membrane protein YuiB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3608 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03609 S100027_03610 S100027_03610 S100027_03610 3407588 3408799 - NADH dehydrogenase FAD%3B Flavoprotein%3B Oxidoreductase%3B Belongs to the NADH dehydrogenase family%3B KEGG: bsu:BSU32100 NADH dehydrogenase gene gene3609 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03610 S100027_03611 S100027_03611 S100027_03611 3409144 3410142 + Thioredoxin-disulfide reductase FAD%3B Flavoprotein%3B NADP%3B Oxidoreductase%3B Belongs to the ferredoxin--NADP reductase type 2 family%3B KEGG: bsu:BSU32110 thioredoxin reductase (NADPH) gene gene3610 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03611 S100027_03612 S100027_03612 S100027_03612 3410177 3410377 - hypothetical protein gene gene3611 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03612 S100027_03613 S100027_03613 S100027_03613 3410520 3410744 + uncharacterized protein gene gene3612 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03613 S100027_03614 S100027_03614 S100027_03614 3410839 3411393 - DNA-3-methyladenine glycosylase I Contains 1 N-acetyltransferase domain%3B KEGG: bha:BH1453 DNA-3-methyladenine glycosylase I gene gene3613 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03614 S100027_03615 S100027_03615 S100027_03615 3411414 3411779 - Iron-sulfur cluster insertion protein ErpA Iron%3B Iron-sulfur%3B Metal-binding%3B Required for insertion of 4Fe-4S clusters for at least IspG%3B Belongs to the HesB/IscA family gene gene3614 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03615 S100027_03616 S100027_03616 dapF dapF 3411854 3412711 - Diaminopimelate epimerase Amino-acid biosynthesis%3B Cytoplasm%3B Disulfide bond%3B Isomerase%3B Lysine biosynthesis%3B Catalyzes the stereoinversion of LL-2%2C6- diaminoheptanedioate (L%2CL-DAP) to meso-diaminoheptanedioate (meso- DAP)%2C a precursor of L-lysine and an essential component of the bacterial peptidoglycan%3B Belongs to the diaminopimelate epimerase family%3B KEGG: bsu:BSU32170 diaminopimelate epimerase gene gene3615 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03616 S100027_03617 S100027_03617 S100027_03617 3412837 3414054 - putative transporter YutK Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the concentrative nucleoside transporter (CNT) (TC 2. A. 41) family gene gene3616 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03617 S100027_03618 S100027_03618 S100027_03618 3414211 3414447 - UPF0349 protein Belongs to the UPF0349 family gene gene3617 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03618 S100027_03619 S100027_03619 S100027_03619 3414719 3415786 + NADH dehydrogenase FAD%3B Flavoprotein%3B Oxidoreductase%3B Belongs to the NADH dehydrogenase family%3B KEGG: blh:BaLi_c34690 NADH dehydrogenase gene gene3618 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03619 S100027_03620 S100027_03620 S100027_03620 3415894 3416265 - Intracellular iron chaperone frataxin Cytoplasm%3B Ion transport%3B Iron%3B Iron transport%3B Metal-binding%3B Transport%3B Possible global iron distributor for the cell. Promotes the biosynthesis of iron-sulfur clusters by delivering Fe to the iron-sulfur cluster assembly scaffold protein SufU. In the presence of SufS and L-cysteine reconstitutes Fe-S clusters on SufU%2C which when further incubated with apo-aconitase (citB) reconstitutes aconitase activity. Able to reconstitute an Fe-S cluster on Thermotoga maritima IscU gene gene3619 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03620 S100027_03621 S100027_03621 S100027_03621 3416594 3416785 - hypothetical protein gene gene3620 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03621 S100027_03622 S100027_03622 S100027_03622 3416782 3417888 - Response regulator aspartate phosphatase Hydrolase%3B Protein phosphatase%3B Repeat%3B TPR repeat%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bli:BL02337 response regulator aspartate phosphatase K%3B Acting on ester bonds gene gene3621 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03622 S100027_03623 S100027_03623 S100027_03623 3418164 3418664 + Phenolic acid decarboxylase PadC Aromatic hydrocarbons catabolism%3B Decarboxylase%3B Detoxification%3B Lyase%3B Involved in the decarboxylation and detoxification of phenolic derivatives. It is able to catalyze the decarboxylation of ferulic%2C p-coumaric and caffeic acids%3B Belongs to the PadC family%3B KEGG: bli:BL02117 phenolic acid decarboxylase%3B Carboxy-lyases gene gene3622 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03623 S100027_03624 S100027_03624 S100027_03624 3418674 3418940 - hypothetical protein gene gene3623 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03624 S100027_03625 S100027_03625 S100027_03625 3419051 3419377 - Putative disulfide oxidoreductase YuzD Disulfide bond%3B Redox-active center. gene gene3624 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03625 S100027_03626 S100027_03626 S100027_03626 3419570 3419809 + Putative nitrogen fixation protein YutI Nitrogen fixation%3B May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins%3B Belongs to the NifU family gene gene3625 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03626 S100027_03627 S100027_03627 apeH apeH 3420046 3422007 - Acylaminoacyl-peptidase Hydrolase%3B Protease%3B Serine protease%3B Belongs to the peptidase S9B family%3B KEGG: bce:BC0192 acylaminoacyl-peptidase gene gene3626 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03627 S100027_03628 S100027_03628 S100027_03628 3422114 3423034 - Homoserine kinase Amino-acid biosynthesis%3B ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Threonine biosynthesis%3B Transferase%3B Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate%3B Belongs to the GHMP kinase family. Homoserine kinase subfamily%3B KEGG: bsu:BSU32240 homoserine kinase gene gene3627 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03628 S100027_03629 S100027_03629 thrC thrC 3423031 3424098 - Threonine synthase Amino-acid biosynthesis%3B Lyase%3B Pyridoxal phosphate%3B Threonine biosynthesis%3B Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine%3B Belongs to the threonine synthase family%3B KEGG: bsl:A7A1_2331 threonine synthase gene gene3628 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03629 S100027_03630 S100027_03630 S100027_03630 3424089 3425390 - Homoserine dehydrogenase Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Isoleucine biosynthesis%3B Methionine biosynthesis%3B NADP%3B Oxidoreductase%3B Threonine biosynthesis%3B Belongs to the homoserine dehydrogenase family%3B Contains 1 ACT domain%3B KEGG: seds:AAY24_06030 homoserine dehydrogenase gene gene3629 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03630 S100027_03631 S100027_03631 gyaR gyaR 3425624 3426586 - Glyoxylate reductase Cytoplasm%3B NAD%3B Oxidoreductase%3B Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GyaR subfamily%3B KEGG: bmq:BMQ_4977 glyoxylate reductase gene gene3630 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03631 S100027_03632 S100027_03632 S100027_03632 3426676 3427698 - Endospore coat-associated protein YutH Membrane%3B Sporulation%3B Involved in sporulation%3B Belongs to the CotS family gene gene3631 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03632 S100027_03633 S100027_03633 S100027_03633 3427849 3428331 + Phosphatidylglycerophosphatase To B. subtilis YutG%3B KEGG: bpu:BPUM_1917 phosphatidylglycerophosphatase A gene gene3632 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03633 S100027_03634 S100027_03634 S100027_03634 3428377 3429147 - 4-nitrophenylphosphatase Hydrolase%3B Belongs to the HAD-like hydrolase superfamily%3B KEGG: bsu:BSU32290 4-nitrophenyl phosphatase gene gene3633 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03634 S100027_03635 S100027_03635 S100027_03635 3429167 3429610 - UPF0331 protein YutE Belongs to the UPF0331 family gene gene3634 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03635 S100027_03636 S100027_03636 S100027_03636 3429635 3429910 - uncharacterized protein Disulfide bond. gene gene3635 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03636 S100027_03637 S100027_03637 S100027_03637 3430013 3430636 + putative lipoprotein YutC Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal. gene gene3636 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03637 S100027_03638 S100027_03638 lipA lipA 3430690 3431586 - Lipoyl synthase 4Fe-4S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B S-adenosyl-L-methionine%3B Transferase%3B Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes%2C thereby converting the octanoylated domains into lipoylated derivatives%3B Belongs to the radical SAM superfamily. Lipoyl synthase family%3B KEGG: bsu:BSU32330 lipoic acid synthetase gene gene3637 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03638 S100027_03639 S100027_03639 S100027_03639 3431839 3432819 + L-Ala--D-Glu endopeptidase Cell cycle%3B Cell wall biogenesis/degradation%3B Differentiation%3B Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Signal%3B Sporulation%3B Zinc%3B L-Ala--D-Glu endopeptidase involved in production of single L-alanine side chains from tetrapeptides in the spore cortex peptidoglycan. Therefore%2C is required for the endospore cortex maturation%3B Belongs to the peptidase M23B family gene gene3638 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03639 S100027_03640 S100027_03640 S100027_03640 3432868 3432981 - hypothetical protein gene gene3639 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03640 S100027_03641 S100027_03641 S100027_03641 3432978 3434507 - putative sodium-dependent transporter YhdH Cell membrane%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Putative sodium-dependent transporter%3B Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2. A. 22) family gene gene3640 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03641 S100027_03642 S100027_03642 S100027_03642 3434693 3435466 - Sporulation protein YunB Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Required for sporulation gene gene3641 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03642 S100027_03643 S100027_03643 S100027_03643 3435534 3435839 - uncharacterized protein gene gene3642 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03643 S100027_03644 S100027_03644 S100027_03644 3435917 3437272 - 5'-nucleotidase Coiled coil%3B Hydrolase%3B Metal-binding%3B Belongs to the metallophosphoesterase superfamily%3B KEGG: llm:llmg_0192 5'-nucleotidase gene gene3643 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03644 S100027_03645 S100027_03645 S100027_03645 3437292 3438113 - UPF0721 transmembrane protein YunE Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0721 family gene gene3644 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03645 S100027_03646 S100027_03646 S100027_03646 3438131 3438982 - UPF0759 protein YunF Belongs to the UPF0759 family gene gene3645 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03646 S100027_03647 S100027_03647 S100027_03647 3439114 3439647 - putative membrane protein YmcC Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3646 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03647 S100027_03648 S100027_03648 S100027_03648 3439738 3440322 + HTH-type transcriptional regulator PksA DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcriptional regulation of the polyketide synthase operon. Contains 1 HTH tetR-type DNA-binding domain gene gene3647 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03648 S100027_03649 S100027_03649 S100027_03649 3440511 3440732 - hypothetical protein gene gene3648 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03649 S100027_03650 S100027_03650 pucG pucG 3441241 3442467 - Purine catabolism protein PucG Aminotransferase%3B Purine metabolism%3B Pyridoxal phosphate%3B Transferase%3B Could encode ureidoglycolase or L-alanine:glyoxylate aminotransferase%2C or perhaps both activities%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bli:BL02152 (S)-ureidoglycine-glyoxylate aminotransferase%3B Transaminases gene gene3649 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03650 S100027_03651 S100027_03651 S100027_03651 3442483 3443736 - Allantoate deiminase Hydrolase%3B Metal-binding%3B Purine metabolism%3B Zinc%3B Involved in the anaerobic utilization of allantoin. Converts allantoate to (S)-ureidoglycolate and ammonia%3B Belongs to the peptidase M20 family%3B KEGG: bli:BL02153 allantoate deiminase gene gene3650 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03651 S100027_03652 S100027_03652 S100027_03652 3443901 3445499 + Purine catabolism regulatory protein Activator%3B DNA-binding%3B Purine metabolism%3B Repressor%3B Transcription%3B Transcription regulation%3B Activates the expression of pucFG%2C pucH%2C pucI%2C pucJKLM and guaD%2C while it represses pucABCDE and its own expression%3B Belongs to the CdaR family gene gene3651 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03652 S100027_03653 S100027_03653 S100027_03653 3445602 3446798 - Multidrug resistance protein Antibiotic resistance%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Energy-dependent efflux pump responsible for decreased drug accumulation in multi-drug-resistant cells. Probably uses a transmembrane proton gradient as the energy source. Causes the efflux of a variety of toxic substances%2C including such structurally diverse compounds as ethidium bromide%2C rhodamine and acridine dyes%2C tetraphenylphosphonium%2C puromycin%2C chloramphenicol%2C doxorubicin%2C and fluoroquinolone antibiotics. Belongs to the major facilitator superfamily. TCR/Tet family gene gene3652 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03653 S100027_03654 S100027_03654 S100027_03654 3446977 3448383 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B To E. coli YfcC and H. influenzae HI_0594 gene gene3653 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03654 S100027_03655 S100027_03655 S100027_03655 3448627 3449361 + Anthranilate phosphoribosyltransferase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Glycosyltransferase%3B Magnesium%3B Metal-binding%3B Transferase%3B Tryptophan biosynthesis%3B Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)%3B Belongs to the anthranilate phosphoribosyltransferase family%3B KEGG: blh:BaLi_c35040 anthranilate phosphoribosyltransferase%3B overlaps another CDS with the same product name gene gene3654 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03655 S100027_03656 S100027_03656 S100027_03656 3449325 3449672 + Anthranilate phosphoribosyltransferase KEGG: blh:BaLi_c35040 anthranilate phosphoribosyltransferase%3B overlaps another CDS with the same product name gene gene3655 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03656 S100027_03657 S100027_03657 S100027_03657 3449752 3450564 + Extracellular ribonuclease Hydrolase%3B Nuclease%3B Secreted%3B Signal%3B Mg(2+)-activated ribonuclease which hydrolyzes RNA apparently nonspecifically into oligonucleotides with 5'-terminal phosphate gene gene3656 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03657 S100027_03658 S100027_03658 ygeS ygeS 3450855 3451694 - Xanthine dehydrogenase KEGG: bce:BC3167 xanthine dehydrogenase molybdenum-binding subunit gene gene3657 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03658 S100027_03659 S100027_03659 dadA dadA 3451895 3453016 - D-arginine dehydrogenase FAD%3B Flavoprotein%3B Oxidoreductase%3B Belongs to the DadA oxidoreductase family%3B KEGG: bsu:BSU32630 D-amino-acid dehydrogenase gene gene3658 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03659 S100027_03660 S100027_03660 S100027_03660 3453082 3453942 - hypothetical protein gene gene3659 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03660 S100027_03661 S100027_03661 S100027_03661 3453973 3454356 - hypothetical protein gene gene3660 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03661 S100027_03662 S100027_03662 S100027_03662 3454640 3454813 - hypothetical protein gene gene3661 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03662 S100027_03663 S100027_03663 S100027_03663 3454944 3456059 - Response regulator aspartate phosphatase J Hydrolase%3B Protein phosphatase%3B Repeat%3B TPR repeat%3B Belongs to the RAP family%3B Contains 5 TPR repeats%3B KEGG: bli:BL02161 response regulator aspartate phosphatase I%3B Acting on ester bonds gene gene3662 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03663 S100027_03664 S100027_03664 S100027_03664 3456506 3457903 - FeS cluster assembly protein SufB The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake from extracellular iron chelators under iron limitation (By similarity)%3B Belongs to the UPF0051 (ycf24) family gene gene3663 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03664 S100027_03665 S100027_03665 S100027_03665 3457922 3458368 - Zinc-dependent sulfurtransferase SufU Metal-binding%3B Transferase%3B Zinc%3B Its function is controversial. Has been generally assumed to be an iron-sulfur cluster assembly scaffold protein (PubMed:20097860%2C PubMed:21236255)%2C but more recent evidence suggest it is a sulfurtransferase rather than a scaffold assembly protein (PubMed:24321018). Has been shown to bind low levels of a labile%2C air-sensitive Fe-S cluste%3B this can be assembled under anaerobic conditions from FeCl(3) and Li(2)S. Has been shown to be able to transfer this Fe-S cluster to an acceptor protein. Stimulates the cysteine desulfurase activity of SufS%2C for which it acts as a second substrate. Alkylation eliminates its ability to stimulate SufS. A mixture of SufS%2C SufU%2C Fra and L-cysteine is able to reconstitute Fe-S clusters on apo-aconitase (citB)%2C reconstituting aconitase activity%3B Belongs to the NifU family gene gene3664 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03665 S100027_03666 S100027_03666 S100027_03666 3458358 3459578 - Cysteine desulfurase Cytoplasm%3B Lyase%3B Pyridoxal phosphate%3B Transferase%3B Cysteine desulfurases mobilize the sulfur from L- cysteine to yield L-alanine%2C an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon%2C which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro%2C that mobilizes selenium from L-selenocysteine. Selenocysteine lyase activity is however unsure in vivo%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily%3B KEGG: bli:BL02164 cysteine desulfurase / selenocysteine lyase gene gene3665 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03666 S100027_03667 S100027_03667 S100027_03667 3459578 3460891 - FeS cluster assembly protein SufD The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake from extracellular iron chelators under iron limitation (By similarity)%3B Belongs to the UPF0051 (ycf24) family gene gene3666 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03667 S100027_03668 S100027_03668 S100027_03668 3460909 3461694 - Vegetative protein 296 ATP-binding%3B Nucleotide-binding%3B Transport%3B Belongs to the ABC transporter superfamily. Ycf16 family%3B Contains 1 ABC transporter domain gene gene3667 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03668 S100027_03669 S100027_03669 S100027_03669 3461923 3462858 - Cadmium%2C cobalt and zinc/H(+)-K(+) antiporter Cadmium%3B Cell membrane%3B Cobalt%3B Cobalt transport%3B Ion transport%3B Membrane%3B Potassium%3B Potassium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Zinc%3B Zinc transport%3B Involved in divalent cation and potassium homeostasis in the cell. Catalyzes the active efflux of zinc%2C cadmium and cobalt%2C in exchange for potassium and H(+) ions (By similarity)%3B Belongs to the cation diffusion facilitator (CDF) transporter (TC 2. A. 4) family. SLC30A subfamily gene gene3668 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03669 S100027_03670 S100027_03670 S100027_03670 3463279 3463647 - 4-carboxymuconolactone decarboxylase KEGG: bca:BCE_2858 4-carboxymuconolactone decarboxylase gene gene3669 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03670 S100027_03671 S100027_03671 S100027_03671 3463754 3464584 - Methionine-binding lipoprotein MetQ Amino-acid transport%3B Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B Part of the ABC transporter complex MetNPQ involved in methionine import. Binds the methionine and transfers it to the membrane-bound permease. It has also been shown to be involved in methionine sulfoxide transport (Probable)%3B Belongs to the NlpA lipoprotein family gene gene3670 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03671 S100027_03672 S100027_03672 S100027_03672 3464598 3465266 - Methionine import system permease protein MetP Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex MetNPQ involved in methionine import. Responsible for the translocation of the substrate across the membrane (Probable). It has also been shown to be involved in methionine sulfoxide transport%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3671 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03672 S100027_03673 S100027_03673 S100027_03673 3465259 3466284 - Lipoprotein-releasing system ATP-binding protein LolD ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins%2C from the inner membrane to the periplasmic chaperone%2C LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner%3B Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3. A. 1. 125) family%3B Contains 1 ABC transporter domain%3B KEGG: yen:YE1199 macrolide transport system ATP-binding/permease protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene3672 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03673 S100027_03674 S100027_03674 S100027_03674 3466692 3467039 - uncharacterized protein gene gene3673 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03674 S100027_03675 S100027_03675 S100027_03675 3467161 3467469 - Thioredoxin-like protein YusE Disulfide bond%3B Redox-active center%3B Contains 1 thioredoxin domain gene gene3674 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03675 S100027_03676 S100027_03676 S100027_03676 3467495 3467839 - uncharacterized protein Contains 1 Toprim domain gene gene3675 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03676 S100027_03677 S100027_03677 S100027_03677 3467902 3468138 - uncharacterized protein gene gene3676 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03677 S100027_03678 S100027_03678 S100027_03678 3468192 3468575 - Glycine cleavage system H protein Lipoyl%3B The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein%3B Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate%3B Belongs to the GcvH family%3B Contains 1 lipoyl-binding domain gene gene3677 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03678 S100027_03679 S100027_03679 S100027_03679 3468637 3468993 - Arsenate reductase (glutaredoxin) Oxidoreductase%3B Belongs to the ArsC family%3B KEGG: bli:BL02177 arsenate reductase gene gene3678 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03679 S100027_03680 S100027_03680 S100027_03680 3469113 3470897 - putative acyl-CoA dehydrogenase FAD%3B Fatty acid metabolism%3B Flavoprotein%3B Lipid degradation%3B Lipid metabolism%3B Oxidoreductase%3B Involved in the degradation of long-chain fatty acids. Belongs to the acyl-CoA dehydrogenase family%3B KEGG: bcl:ABC2988 null%3B With other acceptors gene gene3679 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03680 S100027_03681 S100027_03681 atoB atoB 3470917 3472092 - Acetyl-CoA C-acetyltransferase Acyltransferase%3B Fatty acid metabolism%3B Lipid degradation%3B Lipid metabolism%3B Transferase%3B Involved in the degradation of long-chain fatty acids. Belongs to the thiolase family%3B KEGG: spe:Spro_4857 acetyl-CoA C-acetyltransferase gene gene3680 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03681 S100027_03682 S100027_03682 fadN fadN 3472104 3474494 - 3-hydroxyacyl-CoA dehydrogenase Fatty acid metabolism%3B Lipid degradation%3B Lipid metabolism%3B NAD%3B Oxidoreductase%3B Involved in the degradation of long-chain fatty acids. Belongs to the 3-hydroxyacyl-CoA dehydrogenase family%3B KEGG: bsu:BSU32840 3-hydroxyacyl-CoA dehydrogenase gene gene3681 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03682 S100027_03683 S100027_03683 S100027_03683 3474704 3474865 + hypothetical protein gene gene3682 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03683 S100027_03684 S100027_03684 S100027_03684 3474942 3475190 + uncharacterized protein gene gene3683 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03684 S100027_03685 S100027_03685 S100027_03685 3475201 3475542 + uncharacterized protein gene gene3684 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03685 S100027_03686 S100027_03686 S100027_03686 3475572 3475823 - uncharacterized protein Coiled coil. gene gene3685 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03686 S100027_03687 S100027_03687 S100027_03687 3475824 3476564 - hypothetical protein gene gene3686 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03687 S100027_03688 S100027_03688 S100027_03688 3476557 3477375 - Iron-chelate-transporting ATPase ATP-binding%3B Cell membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Nucleotide-binding%3B Transport%3B Provides the ATPase subunit for at least 2 ABC transporter complexe%3B YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen%2C arthrobactin and corprogen (Probable)%2C and FeuABC/YusV involved in import of the catecholate siderophores bacillibactin and enterobactin (Probable). Probably responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: bsu:BSU32940 iron complex transport system ATP-binding protein gene gene3687 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03688 S100027_03689 S100027_03689 S100027_03689 3477393 3478448 - putative siderophore transport system permease protein YfhA Cell membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen%2C arthrobactin and corprogen%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene3688 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03689 S100027_03690 S100027_03690 S100027_03690 3478445 3479446 - putative siderophore transport system permease protein YfiZ Cell membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Signal%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen%2C arthrobactin and corprogen%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene3689 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03690 S100027_03691 S100027_03691 S100027_03691 3479599 3480576 + putative siderophore-binding lipoprotein YfiY Cell membrane%3B Cytoplasm%3B Ion transport%3B Iron%3B Iron transport%3B Lipoprotein%3B Membrane%3B Palmitate%3B Phosphoprotein%3B Signal%3B Transport%3B Part of the ABC transporter complex YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen%2C arthrobactin and corprogen. Binds the siderophores and delivers them to the surface of YfiZ/YfhA (Probable)%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene3690 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03691 S100027_03692 S100027_03692 S100027_03692 3480616 3481062 - uncharacterized protein Coiled coil%3B Signal. gene gene3691 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03692 S100027_03693 S100027_03693 S100027_03693 3481140 3482924 - Oligoendopeptidase F%2C plasmid Hydrolase%3B Metal-binding%3B Metalloprotease%3B Plasmid%3B Protease%3B Zinc%3B Hydrolyzes peptides containing between 7 and 17 amino acids with a rather wide specificity. Belongs to the peptidase M3B family%3B KEGG: gbm:Gbem_1295 oligoendopeptidase F%3B Metalloendopeptidases gene gene3692 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03693 S100027_03694 S100027_03694 S100027_03694 3483036 3484190 - Serine-type D-Ala-D-Ala carboxypeptidase Carboxypeptidase%3B Cell shape%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Membrane%3B Peptidoglycan synthesis%3B Protease%3B Signal%3B Sporulation%3B Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. Required specifically for the synthesis of the spore form of peptidoglycan (cortex). Belongs to the peptidase S11 family%3B KEGG: bli:BL05330 D-alanyl-D-alanine carboxypeptidase gene gene3693 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03694 S100027_03695 S100027_03695 S100027_03695 3484331 3485173 + 3-oxoacyl-[acyl-carrier-protein] reductase Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: aad:TC41_1190 3-oxoacyl-(acyl-carrier protein) reductase gene gene3694 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03695 S100027_03696 S100027_03696 S100027_03696 3485268 3485732 + Metalloregulation DNA-binding stress protein DNA-binding%3B Stress response%3B Forms highly stable%2C multimeric protein-DNA complexes which accumulate in stationary-phase cells and protect against oxidative killing. Belongs to the Dps family gene gene3695 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03696 S100027_03697 S100027_03697 S100027_03697 3485768 3487138 - Peptidase Do Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Serine protease%3B Stress response%3B Transmembrane%3B Transmembrane helix%3B Degrades abnormal exported proteins and responsible for the propeptide processing of a natural pro-protein and for the maturation of a native protein. It also plays a prominent role in stress (heat shock%2C ethanol%2C puromycin and NaCl) resistance during active exponential growth (Probable)%3B Belongs to the peptidase S1C family%3B Contains 1 PDZ (DHR) domain%3B KEGG: bli:BL00734 serine protease Do gene gene3696 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03697 S100027_03698 S100027_03698 S100027_03698 3487377 3488051 + Transcriptional regulatory protein CssR Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3697 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03698 S100027_03699 S100027_03699 cssS cssS 3488048 3489394 + Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress. Required for the transcription of htrA. Could detect misfolded proteins at the membrane-cell wall interface and then activate CssR by phosphorylation%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: bli:BL00749 two-component system%2C OmpR family%2C sensor histidine kinase CssS gene gene3698 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03699 S100027_03700 S100027_03700 S100027_03700 3489418 3489582 - uncharacterized protein gene gene3699 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03700 S100027_03701 S100027_03701 S100027_03701 3489701 3490654 + putative HTH-type transcriptional regulator YuxN DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH tetR-type DNA-binding domain gene gene3700 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03701 S100027_03702 S100027_03702 fumC fumC 3490700 3492088 - Fumarate hydratase Allosteric enzyme%3B Cytoplasm%3B Lyase%3B Tricarboxylic acid cycle%3B Catalyzes the reversible addition of water to fumarate to give L-malate%3B Belongs to the class-II fumarase/aspartase family. Fumarase subfamily%3B KEGG: hin:HI1398 fumarate hydratase%2C class II gene gene3701 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03702 S100027_03703 S100027_03703 S100027_03703 3492172 3492339 - uncharacterized protein gene gene3702 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03703 S100027_03704 S100027_03704 S100027_03704 3492463 3493905 + Spore germination protein A1 Cell membrane%3B Germination%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Forms a complex at the inner spore membrane which acts as a receptor for L-alanine%2C thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of GerD and GerK gene products (fructose and glucose receptors%2C respectively)%2C but the response is improved in their presence. Belongs to the GerABKA family gene gene3703 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03704 S100027_03705 S100027_03705 S100027_03705 3493874 3494974 + Spore germination protein A2 Amino-acid transport%3B Cell membrane%3B Germination%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the germinative response to L-alanine. Could be an amino acid transporter. Forms a complex at the inner spore membrane which acts as a receptor for L-alanine%2C thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors%2C respectively)%2C but the response is improved in their presence. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2. A. 3. 9) family gene gene3704 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03705 S100027_03706 S100027_03706 S100027_03706 3494971 3496092 + Spore germination protein B3 Cell membrane%3B Germination%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Involved in the response to the germinative mixture of L-asparagine%2C glucose%2C fructose and potassium ions (AGFK). Cannot stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors respectively). Belongs to the GerABKC lipoprotein family gene gene3705 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03706 S100027_03707 S100027_03707 S100027_03707 3496154 3496519 + hypothetical protein gene gene3706 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03707 S100027_03708 S100027_03708 S100027_03708 3496556 3497191 - Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon Chemotaxis%3B Cytoplasm%3B Hydrolase%3B Phosphoprotein%3B Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene3707 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03708 S100027_03709 S100027_03709 liaS liaS 3497195 3498259 - Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system LiaS/LiaR probably involved in response to a subset of cell wall-active antibiotics that interfere with the lipid II cycle in the cytoplasmic membrane (bacitracin%2C nisin%2C ramoplanin and vancomycin). Seems also involved in response to cationic antimicrobial peptides and secretion stress. Activates probably LiaR by phosphorylation%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: bli:BL00729 two-component system%2C NarL family%2C sensor histidine kinase LiaS gene gene3708 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03709 S100027_03710 S100027_03710 S100027_03710 3498256 3498987 - Protein LiaF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3709 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03710 S100027_03711 S100027_03711 S100027_03711 3499018 3499881 - hypothetical protein gene gene3710 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03711 S100027_03712 S100027_03712 S100027_03712 3499987 3500670 - Protein LiaH Coiled coil%3B Belongs to the PspA/IM30 family gene gene3711 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03712 S100027_03713 S100027_03713 S100027_03713 3500691 3501077 - Protein LiaI Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3712 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03713 S100027_03714 S100027_03714 S100027_03714 3501250 3502203 - Pectinesterase Aspartyl esterase%3B Disulfide bond%3B Glycoprotein%3B Hydrolase%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Acts in the modification of cell walls via demethylesterification of cell wall pectin%3B In the N-terminal sectio%3B belongs to the PMEI family%3B In the C-terminal sectio%3B belongs to the pectinesterase family%3B KEGG: bli:BL00724 pectinesterase gene gene3713 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03714 S100027_03715 S100027_03715 mmaB mmaB 3502334 3502912 - Cob(I)yrinic acid a%2Cc-diamide adenosyltransferase ATP-binding%3B Cobalamin biosynthesis%3B Cytoplasm%3B Nucleotide-binding%3B Porphyrin biosynthesis%3B Transferase%3B Belongs to the Cob(I)alamin adenosyltransferase family%3B KEGG: bsu:BSU33150 cob(I)alamin adenosyltransferase gene gene3714 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03715 S100027_03716 S100027_03716 S100027_03716 3503098 3503844 + 3-oxoacyl-[acyl-carrier-protein] reductase NAD%3B Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: mbat:BN1208_0787 3-oxoacyl-(acyl-carrier protein) reductase gene gene3715 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03716 S100027_03717 S100027_03717 pdxA pdxA 3503882 3504100 - 4-hydroxythreonine-4-phosphate dehydrogenase Cobalt%3B Cytoplasm%3B Magnesium%3B Metal-binding%3B NAD%3B NADP%3B Oxidoreductase%3B Pyridoxine biosynthesis%3B Zinc%3B Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)%3B Belongs to the PdxA family%3B KEGG: eco:b0052 4-hydroxythreonine-4-phosphate dehydrogenase gene gene3716 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03717 S100027_03718 S100027_03718 S100027_03718 3504618 3505787 - Alcohol dehydrogenase NAD%3B Oxidoreductase%3B Long-chain alkyl alcohol dehydrogenase that can oxidize a broad range of alkyl alcohols from ethanol to 1-triacontanol (C2 to C30) as well as 1%2C3-propanediol and acetaldehyde. The best substrate is ethanol. Also oxidizes glycerol%3B Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: bld:BLi03502 alcohol dehydrogenase gene gene3717 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03718 S100027_03719 S100027_03719 S100027_03719 3505792 3506694 - 4-hydroxy-tetrahydrodipicolinate synthase Amino-acid biosynthesis%3B Cytoplasm%3B Diaminopimelate biosynthesis%3B Lyase%3B Lysine biosynthesis%3B Schiff base%3B Catalyzes the condensation of (S)-aspartate-beta- semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)%3B Belongs to the DapA family%3B KEGG: msu:MS0282 4-hydroxy-tetrahydrodipicolinate synthase gene gene3718 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03719 S100027_03720 S100027_03720 S100027_03720 3506871 3508154 - Heme-transporting ATPase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Repeat%3B Sugar transport%3B Transport%3B Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose%2C galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Carbohydrate importer 2 (CUT2) (TC 3. A. 1. 2) family%3B Contains 2 ABC transporter domains%3B KEGG: pao:Pat9b_2799 heme exporter protein A gene gene3719 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03720 S100027_03721 S100027_03721 S100027_03721 3508147 3509211 - putative ABC transporter permease protein YvrB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably part of an ABC transporter complex. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene3720 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03721 S100027_03722 S100027_03722 S100027_03722 3509174 3510124 - putative ABC transporter substrate-binding lipoprotein YvrC Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Probably part of an ABC transporter complex%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene3721 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03722 S100027_03723 S100027_03723 S100027_03723 3510504 3511184 + Nta operon transcriptional regulator DNA-binding%3B Transcription%3B Transcription regulation%3B Probable regulator for the expression of the NTA monooxygenase subunits. Contains 1 HTH gntR-type DNA-binding domain gene gene3722 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03723 S100027_03724 S100027_03724 S100027_03724 3511283 3512074 + 3-oxoacyl-[acyl-carrier-protein] reductase Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: pjd:Pjdr2_3073 3-oxoacyl-(acyl-carrier protein) reductase gene gene3723 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03724 S100027_03725 S100027_03725 S100027_03725 3512117 3512812 - uncharacterized protein Contains 1 MOSC domain gene gene3724 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03725 S100027_03726 S100027_03726 S100027_03726 3512973 3513881 + Hydrogen peroxide-inducible protein activator Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase%3B Contains 1 HTH lysR-type DNA-binding domain gene gene3725 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03726 S100027_03727 S100027_03727 S100027_03727 3513919 3515229 - Alpha-L-rhamnosidase Alginate biosynthesis%3B Calcium%3B Isomerase%3B Repeat%3B Secreted%3B Converts beta-D-mannuronic acid (M) to alpha-L-guluronic acid (G). Has both epimerase and lyase activities. Contributes to abortive encystment by degrading the coat from inside the cyst. Important for cyst germination. Belongs to the D-mannuronate C5-epimerase family%3B Contains 8 hemolysin-type calcium-binding repeats%3B Contains 9 PbH1 repeats%3B KEGG: vba:IMCC26134_08560 alpha-L-rhamnosidase gene gene3726 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03727 S100027_03728 S100027_03728 uxaA uxaA 3515243 3516733 - Altronate dehydratase Iron%3B Lyase%3B Manganese%3B Catalyzes the dehydration of D-altronate%3B Belongs to the UxaA family%3B KEGG: bli:BL00712 altronate hydrolase gene gene3727 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03728 S100027_03729 S100027_03729 S100027_03729 3516733 3518202 - Tagaturonate reductase NAD%3B Oxidoreductase%3B Belongs to the mannitol dehydrogenase family. UxaB subfamily%3B KEGG: bli:BL00711 tagaturonate reductase gene gene3728 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03729 S100027_03730 S100027_03730 S100027_03730 3518263 3519261 - Catabolite control protein A Activator%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA)%2C which ensures optimal energy usage under diverse conditions%3B Contains 1 HTH lacI-type DNA-binding domain gene gene3729 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03730 S100027_03731 S100027_03731 S100027_03731 3519341 3520729 - putative symporter YjmB Cell membrane%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the sodium:galactoside symporter (TC 2. A. 2) family gene gene3730 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03731 S100027_03732 S100027_03732 uxaC uxaC 3520765 3522186 - Glucuronate isomerase Isomerase%3B Belongs to the uronate isomerase family%3B KEGG: eco:b3092 glucuronate isomerase gene gene3731 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03732 S100027_03733 S100027_03733 S100027_03733 3522363 3524120 - Sensor histidine kinase YvrG ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA%2C wapA- yxxG%2C dltABCDE%2C sunA%2C sunT-bdbA-yolJ-bdbB%2C sigO-rsoA%2C and sigX- rsiX)%2C and negatively regulates the lytABC operon. Probably activates YvrH by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: ban:BA_1118 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene3732 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03733 S100027_03734 S100027_03734 S100027_03734 3524117 3524845 - Transcriptional regulatory protein YvrH Activator%3B Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Repressor%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA%2C wapA- yxxG%2C dltABCDE%2C sunA%2C sunT-bdbA-yolJ-bdbB%2C sigO-rsoA%2C and sigX- rsiX)%2C and negatively regulates the lytABC operon%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3733 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03734 S100027_03735 S100027_03735 S100027_03735 3525069 3525881 - Iron-chelate-transporting ATPase ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Phosphate transport%3B Transport%3B Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphate importer (TC 3. A. 1. 7) family%3B Contains 1 ABC transporter domain%3B KEGG: eca:ECA1073 iron complex transport system ATP-binding protein gene gene3734 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03735 S100027_03736 S100027_03736 S100027_03736 3525900 3526913 - putative siderophore transport system permease protein YfhA Cell membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen%2C arthrobactin and corprogen%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene3735 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03736 S100027_03737 S100027_03737 S100027_03737 3526913 3527977 - Achromobactin transport system permease protein CbrB Cell inner membrane%3B Cell membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system CbrABCD for uptake of the siderophore achromobactin. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene3736 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03737 S100027_03738 S100027_03738 S100027_03738 3528133 3529536 - Putative arginine/ornithine antiporter Amino-acid transport%3B Antiport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene3737 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03738 S100027_03739 S100027_03739 S100027_03739 3530370 3530840 + uncharacterized protein Cell membrane%3B Membrane%3B Signal%3B Transmembrane%3B Transmembrane helix%3B To E. coli YdjM gene gene3738 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03739 S100027_03740 S100027_03740 S100027_03740 3530940 3532799 + Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase Cell membrane%3B Manganese%3B Membrane%3B Metal-binding%3B Secreted%3B Transmembrane%3B Transmembrane helix%3B Belongs to the LTA synthase family%3B KEGG: baci:B1NLA3E_11025 lipoteichoic acid synthase gene gene3739 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03740 S100027_03741 S100027_03741 S100027_03741 3533001 3534452 + Multidrug export protein Antibiotic resistance%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the tripartite efflux system EmrAB-TolC%2C which confers resistance to antibiotics%3B Belongs to the major facilitator superfamily. EmrB family gene gene3740 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03741 S100027_03742 S100027_03742 dkgA dkgA 3534492 3535331 - 2%2C5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) NADP%3B Oxidoreductase%3B Reduces glyoxal and methylglyoxal. Is not involved in the vitamin B6 biosynthesis%3B Belongs to the aldo/keto reductase family%3B KEGG: yfr:AW19_2489 2%2C5-diketo-D-gluconate reductase A gene gene3741 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03742 S100027_03743 S100027_03743 scrK scrK 3535421 3536281 - Fructokinase ATP-binding%3B Carbohydrate metabolism%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Polysaccharide degradation%3B Transferase%3B Zinc%3B Seems to be involved in the degradation of glucomannan%3B Belongs to the ROK (NagC/XylR) family%3B KEGG: bli:BL00700 fructokinase gene gene3742 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03743 S100027_03744 S100027_03744 kynU kynU 3536548 3537672 + Kynureninase Aminotransferase%3B Pyridoxal phosphate%3B Transferase%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: msv:Mesil_0484 kynureninase gene gene3743 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03744 S100027_03745 S100027_03745 S100027_03745 3537752 3538162 + hypothetical protein gene gene3744 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03745 S100027_03746 S100027_03746 S100027_03746 3538168 3540498 - DNA helicase ATP-binding%3B Coiled coil%3B Cytoplasm%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Catalyzes the unwinding of duplex DNA in the 3' to 5' directio%3B this reaction is dependent on the hydrolysis of ATP%3B Belongs to the helicase family. UvrD subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B KEGG: bli:BL00699 DNA helicase II / ATP-dependent DNA helicase PcrA gene gene3745 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03746 S100027_03747 S100027_03747 S100027_03747 3540677 3541285 - UPF0126 membrane protein YvgT Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0126 family gene gene3746 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03747 S100027_03748 S100027_03748 S100027_03748 3541410 3541760 + UPF0157 protein Belongs to the UPF0157 (GrpB) family gene gene3747 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03748 S100027_03749 S100027_03749 S100027_03749 3541932 3542024 + hypothetical protein gene gene3748 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03749 S100027_03750 S100027_03750 S100027_03750 3542033 3542518 - hypothetical protein gene gene3749 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03750 S100027_03751 S100027_03751 S100027_03751 3542625 3543038 - Disulfide bond formation protein Cell membrane%3B Chaperone%3B Competence%3B Disulfide bond%3B Electron transport%3B Membrane%3B Oxidoreductase%3B Redox-active center%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Required for the stabilization%2C possibly via formation of a disulfide bond%2C of the obligatory competence protein ComGC. Not normally required for production of the secreted lantibiotic sublancin 168%2C although it can partially substitute for BdbB when the latter is absent. It may also be required for the stability of other secreted proteins. Not required for sporulation%3B Belongs to the DsbB family. BdbC subfamily gene gene3750 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03751 S100027_03752 S100027_03752 S100027_03752 3543028 3543723 - Disulfide bond formation protein D Competence%3B Disulfide bond%3B Oxidoreductase%3B Redox-active center%3B Signal%3B Required for the stabilization%2C possibly via formation of a disulfide bond%2C of the obligatory competence protein ComGC. May be required for the stability of secreted proteins with disulfide bonds. Not required for sporulation%3B Belongs to the thioredoxin family. DsbA subfamily%3B Contains 1 thioredoxin domain gene gene3751 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03752 S100027_03753 S100027_03753 S100027_03753 3543849 3545960 - Cadmium-exporting ATPase ATP-binding%3B Cadmium%3B Cadmium resistance%3B Cell membrane%3B Cobalt%3B Cobalt transport%3B Copper%3B Copper transport%3B Hydrolase%3B Ion transport%3B Magnesium%3B Membrane%3B Metal-binding%3B Nucleotide-binding%3B Phosphoprotein%3B Stress response%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Zinc%3B Zinc transport%3B Couples the hydrolysis of ATP with the transport of cadmium%2C zinc and cobalt out of the cell. Does not seem to transport copper%3B Belongs to the cation transport ATPase (P-type) (TC 3. A. 3) family. Type IB subfamily%3B Contains 1 HMA domain%3B KEGG: bli:BL03007 Cd2+/Zn2+-exporting ATPase gene gene3752 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03753 S100027_03754 S100027_03754 S100027_03754 3546213 3547427 + Putative binding protein Periplasm%3B Signal%3B Transport%3B Probably part of an ABC transporter complex. Belongs to the bacterial solute-binding protein 1 family gene gene3753 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03754 S100027_03755 S100027_03755 S100027_03755 3547454 3548347 + Inner membrane ABC transporter permease protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably part of the binding-protein-dependent transport system YcjNOP. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3754 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03755 S100027_03756 S100027_03756 S100027_03756 3548344 3549165 + putative ABC transporter permease protein YurM Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably part of the binding-protein-dependent transport system YurMNO. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3755 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03756 S100027_03757 S100027_03757 yicI yicI 3549187 3551496 + Alpha-D-xyloside xylohydrolase Glycosidase%3B Hydrolase%3B Can catalyze the transfer of alpha-xylosyl residue from alpha-xyloside to xylose%2C glucose%2C mannose%2C fructose%2C maltose%2C isomaltose%2C nigerose%2C kojibiose%2C sucrose and trehalose%3B Belongs to the glycosyl hydrolase 31 family%3B KEGG: scu:SCE1572_13305 alpha-D-xyloside xylohydrolase gene gene3756 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03757 S100027_03758 S100027_03758 bglX bglX 3551512 3554457 + Beta-glucosidase Carbohydrate metabolism%3B Extracellular matrix%3B Glycoprotein%3B Glycosidase%3B Hydrolase%3B Multifunctional enzyme%3B Polysaccharide degradation%3B Secreted%3B Signal%3B Xylan degradation%3B A bifunctional beta-xylosidase/alpha-L-arabinosidase%2C exo-enzyme that acts synergistically with endohydrolases. Releases xylose and arabinose from cell walls. Does not cleave xylan from oat spelts although xylan from oat spelts was degraded to xylose when this enzyme was used in combination with xylanase. Also releases xylose and arabinose from aryl glycosides%2C xylo- oligosaccharides%2C arabinan from sugar beet and arabino- oligosaccharides%2C arabinan from sugar beet and arabinoxylan from wheat%3B Belongs to the glycoside hydrolase 3 family%3B KEGG: bli:BL02680 beta-glucosidase gene gene3757 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03758 S100027_03759 S100027_03759 S100027_03759 3554673 3555425 + Octopine permease ATP-binding protein ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Plasmid%3B Transport%3B Component of the octopine active transport system probably consisting of four subunits: Q%2C M%2C P and T%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene3758 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03759 S100027_03760 S100027_03760 S100027_03760 3555425 3556285 + Manganese transport system membrane protein MntC Cell membrane%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B This protein is probably a component of a manganese permease%2C a binding protein-dependent%2C ATP-driven transport system%3B Belongs to the ABC-3 integral membrane protein family gene gene3759 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03760 S100027_03761 S100027_03761 S100027_03761 3556313 3557242 + Zinc-binding protein AdcA Ion transport%3B Signal%3B Transport%3B Zinc%3B Zinc transport%3B Part of the ATP-driven transport system AdcABC for zinc. Belongs to the bacterial solute-binding protein 9 family gene gene3760 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03761 S100027_03762 S100027_03762 S100027_03762 3557347 3557673 + putative cysteine-rich protein YhjQ gene gene3761 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03762 S100027_03763 S100027_03763 S100027_03763 3557783 3557998 + hypothetical protein gene gene3762 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03763 S100027_03764 S100027_03764 S100027_03764 3558031 3558561 + putative HTH-type transcriptional regulator DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH rpiR-type DNA-binding domain%3B Contains 1 SIS domain gene gene3763 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03764 S100027_03765 S100027_03765 fruK fruK 3558645 3559559 + 1-phosphofructokinase ATP-binding%3B Kinase%3B Lactose metabolism%3B Nucleotide-binding%3B Transferase%3B Belongs to the carbohydrate kinase PfkB family. LacC subfamily%3B KEGG: bli:BL01904 1-phosphofructokinase gene gene3764 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03765 S100027_03766 S100027_03766 S100027_03766 3559573 3560973 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Membrane%3B Phosphoprotein%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport (By similarity)%3B Contains 1 PTS EIIA type-2 domain%3B Contains 1 PTS EIIB type-2 domain%3B Contains 1 PTS EIIC type-2 domain%3B KEGG: bld:BLi03550 PTS system%2C fructose-specific IIB component gene gene3765 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03766 S100027_03767 S100027_03767 S100027_03767 3560980 3561438 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Membrane%3B Phosphoprotein%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport (By similarity)%3B Contains 1 PTS EIIA type-2 domain%3B Contains 1 PTS EIIB type-2 domain%3B Contains 1 PTS EIIC type-2 domain%3B KEGG: bld:BLi03551 PTS system%2C fructose-specific IIA component gene gene3766 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03767 S100027_03768 S100027_03768 S100027_03768 3561464 3562315 + Tagatose-bisphosphate aldolase Galactitol metabolism%3B Lyase%3B Metal-binding%3B Zinc%3B Catalytic subunit of the tagatose-1%2C6-bisphosphate aldolase GatYZ%2C which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1%2C6- bisphosphate (TBP). Requires GatZ subunit for full activity and stability. Is involved in the catabolism of galactitol and D- tagatose%3B Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase GatY subfamily%3B KEGG: bli:BL01900 tagatose 1%2C6-diphosphate aldolase GatY/KbaY gene gene3767 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03768 S100027_03769 S100027_03769 S100027_03769 3562360 3562509 - hypothetical protein gene gene3768 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03769 S100027_03770 S100027_03770 copA copA 3562506 3564941 - Cu(+) exporting ATPase ATP-binding%3B Cell membrane%3B Copper%3B Copper transport%3B Hydrolase%3B Ion transport%3B Magnesium%3B Membrane%3B Metal-binding%3B Nucleotide-binding%3B Phosphoprotein%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in copper export%3B Belongs to the cation transport ATPase (P-type) (TC 3. A. 3) family. Type IB subfamily%3B Contains 2 HMA domains%3B KEGG: bli:BL01899 Cu+-exporting ATPase gene gene3769 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03770 S100027_03771 S100027_03771 S100027_03771 3564978 3565187 - Copper chaperone CopZ Chaperone%3B Copper%3B Cytoplasm%3B Metal-binding%3B Chaperone that serves for the intracellular sequestration and transport of Cu(+). Delivers Cu(+) to the copper-transporting ATPase CopA. Contains 1 HMA domain gene gene3770 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03771 S100027_03772 S100027_03772 S100027_03772 3565282 3565584 - Copper-sensing transcriptional repressor CsoR Copper%3B Cytoplasm%3B DNA-binding%3B Metal-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Copper-sensitive repressor that has a key role in copper homeostasis. Negatively regulates expression of the copZA operon and of ycnJ. In the absence of copper ions%2C binds with high affinity to the copZA promoter and represses the transcription. In the presence of copper ions%2C CsoR binds Cu(1+)%2C which significantly decreases its DNA binding affinity and leads to the transcription of the genes%3B Belongs to the CsoR family gene gene3771 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03772 S100027_03773 S100027_03773 S100027_03773 3565708 3566259 - Protein DJ-1 like protein Lyase%3B Oxidation%3B Repeat%3B Stress response%3B Possesses glyoxalase I activity. Catalyzes the conversion of hemimercaptal%2C formed from methylglyoxal and glutathione%2C to S-lactoylglutathione. May be involved in oxidative stress response%3B Belongs to the peptidase C56 family%3B Contains 2 PfpI endopeptidase domains%3B KEGG: bcy:Bcer98_3045 protease I%3B Glycosylases gene gene3772 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03773 S100027_03774 S100027_03774 S100027_03774 3566345 3567106 - putative HTH-type transcriptional regulator YulB DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH deoR-type DNA-binding domain gene gene3773 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03774 S100027_03775 S100027_03775 rhaB rhaB 3567186 3568667 - Rhamnulokinase ATP-binding%3B Cytoplasm%3B Isomerase%3B Kinase%3B Manganese%3B Metal-binding%3B Multifunctional enzyme%3B Nucleotide-binding%3B Rhamnose metabolism%3B Transferase%3B In the N-terminal sectio%3B belongs to the rhamnulokinase family%3B In the C-terminal sectio%3B belongs to the rhamnose isomerase family%3B KEGG: bli:BL00812 rhamnulokinase gene gene3774 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03775 S100027_03776 S100027_03776 rhaA rhaA 3568664 3569887 - putative sugar isomerase Isomerase%3B Manganese%3B Metal-binding%3B Belongs to the rhamnose isomerase family%3B KEGG: bli:BL00813 L-rhamnose isomerase / sugar isomerase gene gene3775 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03776 S100027_03777 S100027_03777 S100027_03777 3569877 3570266 - hypothetical protein gene gene3776 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03777 S100027_03778 S100027_03778 S100027_03778 3570321 3572390 - putative oxidoreductase YuxG Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bsu:BSU31220 null%3B Oxidoreductases gene gene3777 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03778 S100027_03779 S100027_03779 S100027_03779 3572752 3573870 + putative MFS-type transporter YfhI Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene3778 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03779 S100027_03780 S100027_03780 S100027_03780 3573867 3573956 + hypothetical protein gene gene3779 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03780 S100027_03781 S100027_03781 S100027_03781 3573974 3575200 - putative MFS-type transporter YvmA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily. TCR/Tet family gene gene3780 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03781 S100027_03782 S100027_03782 yvmC yvmC 3575736 3576485 + Cyclo(L-leucyl-L-leucyl) synthase Transferase%3B Involved in the biosynthesis of pulcherrimin%2C a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues%2C such as L- phenylalanine%2C L-leucine and methionine%2C into cyclodipeptides%3B Belongs to the CDPS family%3B KEGG: bli:BL00817 cyclo(L-leucyl-L-leucyl) synthase gene gene3781 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03782 S100027_03783 S100027_03783 S100027_03783 3576482 3577702 + Pulcherriminic acid synthase Heme%3B Iron%3B Metal-binding%3B Monooxygenase%3B Oxidoreductase%3B Involved in the biosynthesis of pulcherrimin%2C a red extracellular pigment. Catalyzes the oxidation of cyclo(L-Leu-L- Leu) (cLL) to yield pulcherriminic acid which forms pulcherrimin via a nonenzymic reaction with Fe(3+). Substrates with small alkyl groups (cAA%2C cLG%2C cLP) exhibit weaker binding to CYP134A1%2C but substrates with larger hydrophobic side chains bind in a similar regime to cLL%3B Belongs to the cytochrome P450 family%3B KEGG: bli:BL00818 pulcherriminic acid synthase gene gene3782 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03783 S100027_03784 S100027_03784 S100027_03784 3577699 3578154 - hypothetical protein gene gene3783 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03784 S100027_03785 S100027_03785 S100027_03785 3578171 3578644 - putative HTH-type transcriptional regulator YvnA Cytoplasm%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH marR-type DNA-binding domain gene gene3784 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03785 S100027_03786 S100027_03786 S100027_03786 3578767 3579204 - Amidase Chloroplast%3B Membrane%3B Plastid%3B Plastid outer membrane%3B Protein transport%3B Repeat%3B TPR repeat%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Chaperone receptor mediating Hsp90-dependent protein targeting to chloroplasts. Bi-functional preprotein receptor acting on both sides of the membrane. Not essential for an efficient import of pre-proteins into plastids%3B Contains 3 TPR repeats%3B KEGG: blh:BaLi_c36320 amidase gene gene3785 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03786 S100027_03787 S100027_03787 S100027_03787 3579279 3579944 - Amidase Acetylation%3B Auxin biosynthesis%3B Cytoplasm%3B Hydrolase%3B Amidase involved in auxin biosynthesis. Converts indole- 3-acetamide into indole-3-acetic acid. Can also use L-asparagine%2C oleamide and 1-naphtalene-acetamide as substrates%2C but not indole- 3-acetonitrile or indole-3-acetyl-L-aspartic acid%3B Belongs to the amidase family%3B KEGG: blh:BaLi_c36320 amidase gene gene3786 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03787 S100027_03788 S100027_03788 iolW iolW 3580134 3581183 + Scyllo-inositol 2-dehydrogenase (NADP(+)) NADP%3B Oxidoreductase%3B Catalyzes the NADP(+)-dependent oxidation of scyllo- inositol to 2%2C4%2C6/3%2C5-pentahydroxycyclohexanone (scyllo-inosose)%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: bli:BL00819 scyllo-inositol 2-dehydrogenase (NADP+) gene gene3787 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03788 S100027_03789 S100027_03789 S100027_03789 3581215 3581850 - FMN-dependent NADH-azoreductase Flavoprotein%3B FMN%3B NAD%3B Oxidoreductase%3B Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH%2C but not NADPH%2C as an electron donor for its activity%3B Belongs to the azoreductase type 1 family%3B KEGG: bli:BL00833 FMN-dependent NADH-azoreductase%3B Acting on other nitrogenous compounds as donors gene gene3788 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03789 S100027_03790 S100027_03790 S100027_03790 3581813 3581992 - hypothetical protein gene gene3789 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03790 S100027_03791 S100027_03791 S100027_03791 3582151 3583119 - UPF0176 protein Belongs to the UPF0176 family%3B Contains 1 rhodanese domain gene gene3790 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03791 S100027_03792 S100027_03792 S100027_03792 3583315 3583533 - Sigma-O factor regulatory protein RsoA Activator%3B Transcription%3B Transcription regulation%3B Together with RNA polymerase sigma factor SigO%2C positively regulates the expression of at least three operons%2C including oxdC-yvrL%2C sigO-rsoA and yvrJ. Required for the acid stress-dependent induction of the oxalate decarboxylase oxdC gene gene3791 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03792 S100027_03793 S100027_03793 S100027_03793 3583508 3584089 - RNA polymerase sigma factor SigO DNA-binding%3B Sigma factor%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Together with its coactivator RsoA%2C positively regulates the expression of at least three operons%2C including oxdC-yvrL%2C sigO-rsoA and yvrJ. Required for the acid stress- dependent induction of the oxalate decarboxylase oxdC%3B Belongs to the sigma-70 factor family gene gene3792 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03793 S100027_03794 S100027_03794 S100027_03794 3584246 3584395 + uncharacterized protein gene gene3793 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03794 S100027_03795 S100027_03795 S100027_03795 3584489 3585643 + Oxalate decarboxylase Cytoplasm%3B Decarboxylase%3B Lyase%3B Manganese%3B Metal-binding%3B Converts oxalate to formate and CO(2) in an O(2)- dependent reaction. Can also catalyze minor side reactions: oxalate oxidation to produce H(2)O(2)%2C and oxalate-dependent%2C H(2)O(2)-independent dye oxidations%3B To B. subtilis OxdD%3B KEGG: bli:BL00821 oxalate decarboxylase gene gene3794 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03795 S100027_03796 S100027_03796 S100027_03796 3585716 3586114 + Membrane-bound negative regulator YvrL Cell membrane%3B Membrane%3B Repressor%3B Transmembrane%3B Transmembrane helix%3B Negatively regulates RNA polymerase sigma factor SigO- dependent transcription. Prevents the expression or secretion of OxdC under nonstress conditions. May act as an anti-sigma factor gene gene3795 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03796 S100027_03797 S100027_03797 S100027_03797 3586211 3586696 + hypothetical protein gene gene3796 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03797 S100027_03798 S100027_03798 S100027_03798 3586849 3587076 + hypothetical protein gene gene3797 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03798 S100027_03799 S100027_03799 S100027_03799 3587201 3587359 - hypothetical protein gene gene3798 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03799 S100027_03800 S100027_03800 S100027_03800 3587559 3588101 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3799 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03800 S100027_03801 S100027_03801 S100027_03801 3588274 3588654 + hypothetical protein gene gene3800 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03801 S100027_03802 S100027_03802 S100027_03802 3588929 3590647 + Putative ribonuclease YwqJ Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Probable toxic component of a toxin-antitoxin (TA) module. The C-terminus may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YwqK%2C but not by antitoxins specific to other toxins with the LXG domain (By similarity)%3B Contains 1 LXG domain gene gene3801 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03802 S100027_03803 S100027_03803 S100027_03803 3590653 3590937 + hypothetical protein gene gene3802 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03803 S100027_03804 S100027_03804 S100027_03804 3590968 3591177 - N-acetylmuramoyl-L-alanine amidase Cell wall biogenesis/degradation%3B Hydrolase%3B Repeat%3B Secreted%3B Signal%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B KEGG: bay:RBAM_012470 N-acetylmuramoyl-L-alanine amidase gene gene3803 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03804 S100027_03805 S100027_03805 S100027_03805 3591918 3592391 - SsrA-binding protein Cytoplasm%3B RNA-binding%3B Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA)%2C required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape%2C replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gen%3B the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide'%2C a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA%2C entering the A-site of stalled ribosomes%2C displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRN%3B the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation%2C which seems to be the essential function of trans- translation%3B Belongs to the SmpB family gene gene3804 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03805 S100027_03806 S100027_03806 vacB vacB 3592503 3594806 - Ribonuclease Cytoplasm%3B Exonuclease%3B Hydrolase%3B Nuclease%3B RNA-binding%3B 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs%3B Belongs to the RNR ribonuclease family. RNase R subfamily%3B Contains 1 S1 motif domain%3B KEGG: bli:BL03482 ribonuclease R%3B Acting on ester bonds gene gene3805 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03806 S100027_03807 S100027_03807 S100027_03807 3594820 3595566 - Carboxylesterase Hydrolase%3B Serine esterase%3B Involved in the detoxification of xenobiotics. Shows maximal activity with C6 substrates%2C with gradually decreasing activity from C8 to C12 substrates. No activity for higher chain length substrates acids rather than long-chain ones (By similarity)%3B Belongs to the lipase/esterase LIP3/BchO family%3B KEGG: bli:BL03481 carboxylesterase gene gene3806 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03807 S100027_03808 S100027_03808 S100027_03808 3595707 3595937 - putative protein-export membrane protein SecG Cell membrane%3B Membrane%3B Protein transport%3B Translocation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in protein export. Participates in an early event of protein translocation (By similarity)%3B Belongs to the SecG family gene gene3807 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03808 S100027_03809 S100027_03809 S100027_03809 3596108 3596392 - Transition state regulatory protein AbrB Activator%3B DNA-binding%3B Repressor%3B Sporulation%3B Transcription%3B Transcription regulation%3B Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites%2C it may be the sole repressor of tycA transcription%3B Contains 1 SpoVT-AbrB domain%3B To B. subtilis Abh and SpoVT gene gene3808 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03809 S100027_03810 S100027_03810 S100027_03810 3596421 3596738 - putative HTH-type transcriptional regulator YvzC Cytoplasm%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene3809 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03810 S100027_03811 S100027_03811 S100027_03811 3596807 3597208 + HTH-type transcriptional repressor RghR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Represses the expression of yvaM and both rapG and rapH. Binds directly to the promoter regions of yvaM%2C rapG and rapH%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene3810 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03811 S100027_03812 S100027_03812 S100027_03812 3597378 3597776 + Repressor LexA DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH cro/C1-type DNA-binding domain%3B KEGG: aac:Aaci_2954 repressor LexA gene gene3811 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03812 S100027_03813 S100027_03813 S100027_03813 3597824 3598501 - Choline transport system permease protein OpuBD Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in a high affinity multicomponent binding- protein-dependent transport system for cholin%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3812 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03813 S100027_03814 S100027_03814 S100027_03814 3598518 3599435 - Glycine betaine/carnitine/choline-binding protein OpuCC Amino-acid transport%3B Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B Member of a high affinity multicomponent binding- protein-dependent transport system for glycine betaine%2C carnitine%2C and choline%3B Belongs to the OsmX family gene gene3813 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03814 S100027_03815 S100027_03815 S100027_03815 3599449 3600102 - Glycine betaine/carnitine/choline transport system permease protein OpuCB Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine%2C carnitine and cholin%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3814 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03815 S100027_03816 S100027_03816 S100027_03816 3600124 3601263 - Energy-coupling factor transporter ATP-binding protein EcfA ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the ABC transporter superfamily. Energy- coupling factor EcfA family%3B Contains 1 ABC transporter domain gene gene3815 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03816 S100027_03817 S100027_03817 S100027_03817 3601521 3602060 + HTH-type transcriptional repressor OpcR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Negatively regulates the transcription of the opuC operon. In the absence of GbsR%2C is also a negative regulator of the opuB operon. Binds to an inverted repeat in the promoter region of the operons%3B Belongs to the GbsR family gene gene3816 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03817 S100027_03818 S100027_03818 S100027_03818 3602107 3602739 - UPF0056 membrane protein YvbG Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0056 (MarC) family gene gene3817 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03818 S100027_03819 S100027_03819 S100027_03819 3602902 3603681 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3818 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03819 S100027_03820 S100027_03820 S100027_03820 3603725 3604852 - putative membrane protein YvbJ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B overlaps another CDS with the same product name gene gene3819 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03820 S100027_03821 S100027_03821 S100027_03821 3604827 3605492 - putative membrane protein YvbJ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B overlaps another CDS with the same product name gene gene3820 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03821 S100027_03822 S100027_03822 S100027_03822 3605621 3606568 - Fe(3+)-citrate-binding protein YfmC Cell membrane%3B Ion transport%3B Iron%3B Iron transport%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B Part of the ABC transporter complex YfmCDEF involved in citrate-dependent Fe(3+) import. Binds citrate-dependent Fe(3+) and delivers it to the surface of YfmDE (Probable)%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene3821 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03822 S100027_03823 S100027_03823 S100027_03823 3606856 3607248 + hypothetical protein gene gene3822 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03823 S100027_03824 S100027_03824 S100027_03824 3607851 3608483 - putative protease YoaZ Hydrolase%3B Protease%3B Belongs to the peptidase C56 family%3B Contains 1 PfpI endopeptidase domain gene gene3823 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03824 S100027_03825 S100027_03825 S100027_03825 3608619 3609911 - Phosphopyruvate hydratase Cytoplasm%3B Glycolysis%3B Lyase%3B Magnesium%3B Metal-binding%3B Secreted%3B Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis%3B Belongs to the enolase family%3B KEGG: bsu:BSU33900 enolase gene gene3824 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03825 S100027_03826 S100027_03826 gpmI gpmI 3609934 3611469 - Phosphoglycerate mutase (2%2C3-diphosphoglycerate-independent) Glycolysis%3B Isomerase%3B Manganese%3B Metal-binding%3B Phosphoprotein%3B Sporulation%3B Essential for rapid growth and for sporulation. Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate%3B Belongs to the BPG-independent phosphoglycerate mutase family%3B KEGG: bli:BL03467 2%2C3-bisphosphoglycerate-independent phosphoglycerate mutase gene gene3825 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03826 S100027_03827 S100027_03827 tpiA tpiA 3611462 3612223 - Triose-phosphate isomerase Cytoplasm%3B Gluconeogenesis%3B Glycolysis%3B Isomerase%3B Pentose shunt%3B Belongs to the triosephosphate isomerase family%3B KEGG: mej:Q7A_2894 triosephosphate isomerase (TIM) gene gene3826 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03827 S100027_03828 S100027_03828 S100027_03828 3612254 3613438 - Phosphoglycerate kinase ATP-binding%3B Cytoplasm%3B Glycolysis%3B Kinase%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Belongs to the phosphoglycerate kinase family%3B KEGG: sat:SYN_01396 phosphoglycerate kinase gene gene3827 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03828 S100027_03829 S100027_03829 S100027_03829 3613612 3614619 - Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) Cytoplasm%3B Glycolysis%3B NAD%3B Nucleotide-binding%3B Oxidoreductase%3B Involved in the glycolysis. Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1%2C3- bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue%2C and this hemiacetal intermediate is then oxidized to a thioester%2C with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD%2C and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG%3B Belongs to the glyceraldehyde-3-phosphate dehydrogenase family%3B KEGG: eco:b1779 glyceraldehyde 3-phosphate dehydrogenase gene gene3828 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03829 S100027_03830 S100027_03830 S100027_03830 3614653 3615693 - Central glycolytic protein regulator DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B In the absence of glucose%2C represses the transcription of the gapA operon%2C which encodes five key glycolytic enzymes. Binds specifically to the cggR-gapA promoter region and blocks the progression of the RNA polymerase%2C leading to the arrest of the transcription%3B Belongs to the SorC transcriptional regulatory family gene gene3829 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03830 S100027_03831 S100027_03831 S100027_03831 3616095 3617102 - uncharacterized protein To bacterial alkanal monooxygenase alpha and beta chains gene gene3830 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03831 S100027_03832 S100027_03832 S100027_03832 3617242 3618597 - Putative histidine permease Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene3831 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03832 S100027_03833 S100027_03833 S100027_03833 3619241 3619714 + hypothetical protein gene gene3832 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03833 S100027_03834 S100027_03834 S100027_03834 3619891 3620817 - Galactose/methyl galactoside import ATP-binding protein MglA ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Repeat%3B Sugar transport%3B Transport%3B Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3. A. 1. 2. 3) family%3B Contains 2 ABC transporter domains gene gene3833 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03834 S100027_03835 S100027_03835 S100027_03835 3620817 3621506 - hypothetical protein gene gene3834 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03835 S100027_03836 S100027_03836 S100027_03836 3621840 3622562 - Lactate utilization protein Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source%3B Belongs to the LutC/YkgG family%3B overlaps another CDS with the same product name gene gene3835 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03836 S100027_03837 S100027_03837 S100027_03837 3622559 3623992 - Lactate utilization protein 4Fe-4S%3B Electron transport%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Repeat%3B Transport%3B Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate%3B Belongs to the LutB/YkgF family%3B Contains 2 4Fe-4S ferredoxin-type domains%3B overlaps another CDS with the same product name gene gene3836 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03837 S100027_03838 S100027_03838 S100027_03838 3624036 3624821 - Lactate utilization protein A Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source%3B Belongs to the LutA/YkgE family gene gene3837 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03838 S100027_03839 S100027_03839 S100027_03839 3624895 3625635 - Exu regulon transcriptional regulator DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the ExuT%2C UxaCA and UxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers. Contains 1 HTH gntR-type DNA-binding domain gene gene3838 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03839 S100027_03840 S100027_03840 S100027_03840 3625843 3627534 + L-lactate permease Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Is the principal permease for the uptake of L-lactate in B. subtilis%3B Belongs to the lactate permease family gene gene3839 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03840 S100027_03841 S100027_03841 S100027_03841 3627568 3628881 - RNA polymerase sigma-54 factor DNA-binding%3B DNA-directed RNA polymerase%3B Nucleotidyltransferase%3B Sigma factor%3B Transcription%3B Transcription regulation%3B Transferase%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of the levanase operon. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for receipt of the melting signal from the remotely bound activator protein LevR for the expression of the levanase operon. Belongs to the sigma-54 factor family gene gene3840 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03841 S100027_03842 S100027_03842 S100027_03842 3628952 3629167 + uncharacterized protein gene gene3841 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03842 S100027_03843 S100027_03843 epsO epsO 3629183 3630160 - Putative pyruvyl transferase EpsO Exopolysaccharide synthesis%3B Transferase%3B May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Belongs to the polysaccharide pyruvyl transferase family%3B KEGG: bli:BL03453 pyruvyl transferase EpsO%3B Transferases gene gene3842 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03843 S100027_03844 S100027_03844 epsN epsN 3630171 3631316 - Putative pyridoxal phosphate-dependent aminotransferase EpsN Aminotransferase%3B Exopolysaccharide synthesis%3B Pyridoxal phosphate%3B Transferase%3B May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Belongs to the DegT/DnrJ/EryC1 family%3B KEGG: bli:BL03452 pyridoxal phosphate-dependent aminotransferase EpsN%3B Transaminases gene gene3843 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03844 S100027_03845 S100027_03845 epsM epsM 3631340 3631966 - Putative acetyltransferase EpsM Acyltransferase%3B Exopolysaccharide synthesis%3B Repeat%3B Transferase%3B May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Belongs to the transferase hexapeptide repeat family%3B KEGG: bli:BL03451 acetyltransferase EpsM%3B Transferring groups other than amino-acyl groups gene gene3844 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03845 S100027_03846 S100027_03846 S100027_03846 3631966 3632568 - Undecaprenyl-phosphate glucose phosphotransferase Exopolysaccharide synthesis%3B Glycosyltransferase%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Involved in the biosynthesis of the exopolysaccharide acetan%2C a water-soluble polysaccharide involved in production of bacterial cellulose (BC)%3B Belongs to the bacterial sugar transferase family gene gene3845 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03846 S100027_03847 S100027_03847 S100027_03847 3632589 3634145 - putative membrane protein EpsK Cell membrane%3B Exopolysaccharide synthesis%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3846 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03847 S100027_03848 S100027_03848 epsJ epsJ 3634142 3635161 - Chondroitin synthase Glycosyltransferase%3B Repeat%3B Transferase%3B Catalyzes the polymerization of chondroitin%2C a polysaccharide composed of a repeating disaccharide of N- acetylgalactosamine (GalNAc) and glucuronic acid (GlcUA) units. Each unit has the composition in beta-(1->4)-GlcUA-beta-(1->3)- GalNAc. Belongs to the glycosyltransferase 2 family. CS/HAS subfamily%3B KEGG: bli:BL03447 glycosyltransferase EpsJ%3B Glycosyltransferases gene gene3847 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03848 S100027_03849 S100027_03849 epsI epsI 3635158 3636237 - Putative pyruvyl transferase EpsI Exopolysaccharide synthesis%3B Transferase%3B May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Belongs to the polysaccharide pyruvyl transferase family%3B KEGG: bli:BL03446 pyruvyl transferase EpsI%3B Transferases gene gene3848 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03849 S100027_03850 S100027_03850 epsH epsH 3636249 3637280 - Putative glycosyltransferase EpsH Exopolysaccharide synthesis%3B Glycosyltransferase%3B Transferase%3B May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance%3B Belongs to the glycosyltransferase 2 family%3B KEGG: bli:BL03445 glycosyltransferase EpsH%3B Glycosyltransferases gene gene3849 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03850 S100027_03851 S100027_03851 S100027_03851 3637340 3638443 - Transmembrane protein EpsG Cell membrane%3B Exopolysaccharide synthesis%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3850 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03851 S100027_03852 S100027_03852 epsF epsF 3638448 3639608 - Putative glycosyltransferase EpsF Exopolysaccharide synthesis%3B Glycosyltransferase%3B Transferase%3B May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance. Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: bli:BL03443 glycosyltransferase EpsF%3B Glycosyltransferases gene gene3851 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03852 S100027_03853 S100027_03853 epsE epsE 3639601 3640443 - Putative glycosyltransferase EpsE Exopolysaccharide synthesis%3B Glycosyltransferase%3B Transferase%3B May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance. Belongs to the glycosyltransferase 2 family%3B KEGG: bli:BL03442 glycosyltransferase EpsE%3B Glycosyltransferases gene gene3852 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03853 S100027_03854 S100027_03854 epsD epsD 3640440 3641588 - Putative glycosyltransferase EpsD Exopolysaccharide synthesis%3B Glycosyltransferase%3B Transferase%3B May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance. Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: bli:BL03441 glycosyltransferase EpsD%3B Glycosyltransferases gene gene3853 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03854 S100027_03855 S100027_03855 S100027_03855 3641599 3643416 - putative polysaccharide biosynthesis protein EpsC Cell membrane%3B Exopolysaccharide synthesis%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Involved in biofilm formation%3B Belongs to the polysaccharide synthase family gene gene3854 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03855 S100027_03856 S100027_03856 epsB epsB 3643677 3644369 - Non-specific protein-tyrosine kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Tyrosine-protein kinase%3B Belongs to the CpsD/CapB family%3B KEGG: bli:BL03438 protein-tyrosine kinase gene gene3855 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03856 S100027_03857 S100027_03857 S100027_03857 3644359 3645111 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the CpsC/CapA family gene gene3856 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03857 S100027_03858 S100027_03858 S100027_03858 3645347 3645805 + HTH-type transcriptional regulator SlrR DNA-binding%3B Transcription%3B Transcription regulation%3B Represses sigma(D)-dependent flagellar genes and activate the eps and yqxM operons. Repressor activity is regulated by SlrA. Controls the initiation of biofilm formation%3B Contains 1 HTH cro/C1-type DNA-binding domain%3B Contains 1 Sin domain gene gene3857 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03858 S100027_03859 S100027_03859 S100027_03859 3646215 3646739 + General stress protein Oxidoreductase%3B Stress response%3B Belongs to the NAD(P)H dehydrogenase (quinone) family gene gene3858 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03859 S100027_03860 S100027_03860 S100027_03860 3646776 3648059 - putative glucarate transporter Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Uptake of D-glucarate. Belongs to the major facilitator superfamily. Phthalate permease family gene gene3859 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03860 S100027_03861 S100027_03861 S100027_03861 3648129 3649079 - Phosphoglycerate dehydrogenase Amino-acid biosynthesis%3B NAD%3B Oxidoreductase%3B Serine biosynthesis%3B Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family%3B Contains 1 ACT domain%3B KEGG: kpu:KP1_2666 D-3-phosphoglycerate dehydrogenase gene gene3860 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03861 S100027_03862 S100027_03862 S100027_03862 3649107 3650105 - 4-hydroxythreonine-4-phosphate dehydrogenase Cytoplasm%3B Metal-binding%3B NAD%3B NADP%3B Oxidoreductase%3B Pyridoxine biosynthesis%3B Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)%3B Belongs to the PdxA family%3B KEGG: bli:BL03434 4-hydroxythreonine-4-phosphate dehydrogenase gene gene3861 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03862 S100027_03863 S100027_03863 S100027_03863 3650109 3651380 - uncharacterized protein To E. coli YgbK gene gene3862 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03863 S100027_03864 S100027_03864 adhE adhE 3651394 3652560 - Acetaldehyde dehydrogenase (acetylating) Cytoplasm%3B Magnesium%3B Methanol utilization%3B NAD%3B Oxidoreductase%3B Zinc%3B Catalyzes the oxidation of methanol to yield formaldehyde. It possesses a NADH-dependent formaldehyde reductase activity and can not use NADP%3B Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: hor:Hore_02110 acetaldehyde dehydrogenase / alcohol dehydrogenase gene gene3863 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03864 S100027_03865 S100027_03865 S100027_03865 3652574 3653461 - 4-hydroxy-tetrahydrodipicolinate synthase Amino-acid biosynthesis%3B Cytoplasm%3B Diaminopimelate biosynthesis%3B Lyase%3B Lysine biosynthesis%3B Schiff base%3B Catalyzes the condensation of (S)-aspartate-beta- semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)%3B Belongs to the DapA family%3B KEGG: bli:BL03431 4-hydroxy-tetrahydrodipicolinate synthase gene gene3864 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03865 S100027_03866 S100027_03866 S100027_03866 3653605 3655323 - Propionate catabolism operon regulatory protein ATP-binding%3B DNA-binding%3B Nucleotide-binding%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Involved in the transcriptional regulation of the propionate catabolism operon. Contains 1 sigma-54 factor interaction domain gene gene3865 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03866 S100027_03867 S100027_03867 S100027_03867 3655295 3655747 - putative HTH-type transcriptional regulator DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH hxlR-type DNA-binding domain gene gene3866 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03867 S100027_03868 S100027_03868 fadH fadH 3655919 3657013 + 2%2C4-dienoyl-CoA reductase (NADPH) FAD%3B Flavoprotein%3B NAD%3B Oxidoreductase%3B Belongs to the NADH:flavin oxidoreductase/NADH oxidase family%3B KEGG: bur:Bcep18194_C7286 2%2C4-dienoyl-CoA reductase (NADPH2) gene gene3867 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03868 S100027_03869 S100027_03869 sacB sacB 3657363 3658811 + Levansucrase Glycosyltransferase%3B Secreted%3B Signal%3B Transferase%3B Belongs to the glycosyl hydrolase 68 family%3B KEGG: blh:BaLi_c37120 levansucrase gene gene3868 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03869 S100027_03870 S100027_03870 levB levB 3658888 3660435 + 2%2C6-beta-fructan 6-levanbiohydrolase Carbohydrate metabolism%3B Cell membrane%3B Glycosidase%3B Hydrolase%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the degradation of levan mainly into levanbiose (difructose). Is not active on sucrose%3B Belongs to the glycosyl hydrolase 32 family%3B KEGG: bli:BL03606 levanbiose-producing levanase gene gene3869 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03870 S100027_03871 S100027_03871 S100027_03871 3660561 3660636 - tRNA-Arg tRNA gene3870 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03871 S100027_03872 S100027_03872 S100027_03872 3660733 3661050 - hypothetical protein gene gene3871 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03872 S100027_03873 S100027_03873 S100027_03873 3661291 3661887 + Endopeptidase Clp Cytoplasm%3B Hydrolase%3B Protease%3B Serine protease%3B Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins%3B Belongs to the peptidase S14 family%3B KEGG: eco:b0437 ATP-dependent Clp protease%2C protease subunit gene gene3872 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03873 S100027_03874 S100027_03874 S100027_03874 3661967 3662542 - putative cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG6 Cytokinin biosynthesis%3B Hydrolase%3B Cytokinin-activating enzyme working in the direct activation pathway. Phosphoribohydrolase that converts inactive cytokinin nucleotides to the biologically active free-base forms (By similarity)%3B Belongs to the LOG family gene gene3873 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03874 S100027_03875 S100027_03875 S100027_03875 3662654 3662989 + uncharacterized protein overlaps another CDS with the same product name gene gene3874 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03875 S100027_03876 S100027_03876 S100027_03876 3662961 3663953 + uncharacterized protein Contains 1 HD domain%3B overlaps another CDS with the same product name gene gene3875 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03876 S100027_03877 S100027_03877 S100027_03877 3664000 3665619 - Putative sulfate transporter YvdB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the SLC26A/SulP transporter (TC 2. A. 53) family%3B Contains 1 STAS domain gene gene3876 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03877 S100027_03878 S100027_03878 S100027_03878 3665641 3666231 - Carbonate dehydratase Lyase%3B Metal-binding%3B Zinc%3B Reversible hydration of carbon dioxide%3B Belongs to the beta-class carbonic anhydrase family%3B KEGG: bli:BL03424 carbonic anhydrase gene gene3877 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03878 S100027_03879 S100027_03879 S100027_03879 3666628 3667599 + Gluconate 2-dehydrogenase Gluconate utilization%3B NADP%3B Oxidoreductase%3B Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family%3B KEGG: bsu:BSU34680 gluconate 2-dehydrogenase gene gene3878 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03879 S100027_03880 S100027_03880 S100027_03880 3667610 3668209 - uncharacterized protein Flavoprotein%3B Belongs to the flavoredoxin family gene gene3879 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03880 S100027_03881 S100027_03881 S100027_03881 3668298 3668993 + putative HTH-type transcriptional regulator YdfF DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH arsR-type DNA-binding domain gene gene3880 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03881 S100027_03882 S100027_03882 S100027_03882 3669251 3669706 + Ribonuclease Endonuclease%3B Hydrolase%3B Nuclease%3B Secreted%3B Signal%3B Hydrolyzes phosphodiester bonds in RNA%2C poly- and oligoribonucleotides resulting in 3'-nucleoside monophosphates via 2'%2C3'-cyclophosphate intermediates. Belongs to the ribonuclease N1/T1 family gene gene3881 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03882 S100027_03883 S100027_03883 S100027_03883 3669711 3669986 + Barstar Cytoplasm%3B Inhibitor of the ribonuclease barnase. Forms a one-to- one non-covalent complex. Belongs to the barstar family gene gene3882 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03883 S100027_03884 S100027_03884 nhoA nhoA 3670054 3670812 - N-hydroxyarylamine O-acetyltransferase Acyltransferase%3B Transferase%3B Belongs to the arylamine N-acetyltransferase family%3B KEGG: blh:BaLi_c37260 N-hydroxyarylamine O-acetyltransferase gene gene3883 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03884 S100027_03885 S100027_03885 S100027_03885 3670855 3671124 - HPr-like protein Crh Phosphoprotein%3B Along with seryl-phosphorylated HPr%2C phosphorylated Crh is implicated in carbon catabolite repression (CCR) of levanase%2C inositol dehydrogenase%2C and beta-xylosidase. Exerts its effect on CCR by interacting with CcpA%3B Belongs to the HPr family%3B Contains 1 HPr domain gene gene3884 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03885 S100027_03886 S100027_03886 S100027_03886 3671142 3672092 - Putative sporulation transcription regulator WhiA DNA-binding%3B Transcription%3B Transcription regulation%3B May be required for sporulation%3B Belongs to the WhiA transcriptional regulatory family gene gene3885 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03886 S100027_03887 S100027_03887 S100027_03887 3672121 3673116 - Gluconeoproteinis factor Cytoplasm%3B Required for morphogenesis under gluconeogenic growth conditions. Required%2C in gluconeogenic growth conditions%2C for the correct localization of PBP1 and hence for displaying a normal rod shape%3B Belongs to the gluconeogenesis factor family gene gene3886 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03887 S100027_03888 S100027_03888 S100027_03888 3673076 3673963 - Nucleotide-binding protein ATP-binding%3B GTP-binding%3B Nucleotide-binding%3B Displays ATPase and GTPase activities%3B Belongs to the RapZ-like family gene gene3887 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03888 S100027_03889 S100027_03889 S100027_03889 3673985 3674449 - 8-oxo-dGTP diphosphatase Hydrolase%3B Magnesium%3B Metal-binding%3B Belongs to the Nudix hydrolase family%3B Contains 1 nudix hydrolase domain%3B KEGG: bsu:BSU34780 8-oxo-dGTP diphosphatase gene gene3888 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03889 S100027_03890 S100027_03890 S100027_03890 3674870 3675820 - Thioredoxin-disulfide reductase Cytoplasm%3B Disulfide bond%3B FAD%3B Flavoprotein%3B NADP%3B Oxidoreductase%3B Redox-active center%3B Stress response%3B Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: rsl:RPSI07_mp0554 thioredoxin reductase (NADPH) gene gene3889 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03890 S100027_03891 S100027_03891 S100027_03891 3675987 3677447 - TPR repeat-containing protein YvcD Repeat%3B TPR repeat%3B Contains 3 TPR repeats gene gene3890 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03891 S100027_03892 S100027_03892 S100027_03892 3677742 3678221 + putative N-acetyltransferase YbbJ Acyltransferase%3B Transferase%3B Contains 1 N-acetyltransferase domain gene gene3891 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03892 S100027_03893 S100027_03893 S100027_03893 3678280 3678912 - Phosphoribosyl-ATP diphosphatase Amino-acid biosynthesis%3B Cytoplasm%3B Histidine biosynthesis%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Zinc%3B Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP%3B Belongs to the PRA-CH family%3B KEGG: bli:BL03413 phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase gene gene3892 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03893 S100027_03894 S100027_03894 hisF hisF 3678909 3679667 - Imidazole glycerol phosphate synthase subunit HisF Amino-acid biosynthesis%3B Cytoplasm%3B Histidine biosynthesis%3B Lyase%3B IGPS catalyzes the conversion of PRFAR and glutamine to IGP%2C AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit%3B Belongs to the HisA/HisF family%3B KEGG: xfa:XF2214 cyclase%3B Oxo-acid-lyases gene gene3893 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03894 S100027_03895 S100027_03895 hisA hisA 3679664 3680401 - 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamideisomerase Amino-acid biosynthesis%3B Cytoplasm%3B Histidine biosynthesis%3B Isomerase%3B Belongs to the HisA/HisF family%3B KEGG: bli:BL03411 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase gene gene3894 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03895 S100027_03896 S100027_03896 hisH hisH 3680398 3681036 - Imidazole glycerol phosphate synthase subunit HisH Amino-acid biosynthesis%3B Cytoplasm%3B Glutamine amidotransferase%3B Histidine biosynthesis%3B Transferase%3B IGPS catalyzes the conversion of PRFAR and glutamine to IGP%2C AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: cff:CFF8240_1352 glutamine amidotransferase%3B Pentosyltransferases gene gene3895 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03896 S100027_03897 S100027_03897 hisB hisB 3681037 3681621 - Imidazoleglycerol-phosphate dehydratase Amino-acid biosynthesis%3B Cytoplasm%3B Histidine biosynthesis%3B Lyase%3B Belongs to the imidazoleglycerol-phosphate dehydratase family%3B KEGG: hba:Hbal_3133 imidazoleglycerol-phosphate dehydratase gene gene3896 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03897 S100027_03898 S100027_03898 hisD hisD 3681621 3682901 - Histidinol dehydrogenase Amino-acid biosynthesis%3B Histidine biosynthesis%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Zinc%3B Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine%3B Belongs to the histidinol dehydrogenase family%3B KEGG: bsu:BSU34910 histidinol dehydrogenase gene gene3897 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03898 S100027_03899 S100027_03899 hisG hisG 3682898 3683539 - ATP phosphoribosyltransferase Amino-acid biosynthesis%3B ATP-binding%3B Cytoplasm%3B Glycosyltransferase%3B Histidine biosynthesis%3B Nucleotide-binding%3B Transferase%3B Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity%3B Belongs to the ATP phosphoribosyltransferase family. Short subfamily%3B KEGG: csa:Csal_2213 ATP phosphoribosyltransferase gene gene3898 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03899 S100027_03900 S100027_03900 S100027_03900 3683532 3684707 - ATP phosphoribosyltransferase regulatory subunit Amino-acid biosynthesis%3B Cytoplasm%3B Histidine biosynthesis%3B Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine%3B Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily gene gene3899 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03900 S100027_03901 S100027_03901 S100027_03901 3684943 3685677 + uncharacterized protein Signal. gene gene3900 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03901 S100027_03902 S100027_03902 pelC pelC 3685961 3686626 + Pectate lyase Calcium%3B Lyase%3B Metal-binding%3B Secreted%3B Signal%3B Catalyzes the depolymerization of both polygalacturonate and pectins of methyl esterification degree from 22 to 89%25%2C with an endo mode of action. In contrast to the majority of pectate lyases%2C displays high activity on highly methylated pectins (By similarity)%3B Belongs to the polysaccharide lyase 3 family%3B KEGG: bli:BL03597 pectate lyase C gene gene3901 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03902 S100027_03903 S100027_03903 lacA lacA 3686656 3687174 - Galactoside O-acetyltransferase Acyltransferase%3B Repeat%3B Transferase%3B Belongs to the transferase hexapeptide repeat family%3B KEGG: nph:NP_4198A galactoside O-acetyltransferase gene gene3902 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03903 S100027_03904 S100027_03904 ppaX ppaX 3687171 3687818 - Inorganic diphosphatase Hydrolase%3B Magnesium%3B Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool%3B Belongs to the HAD-like hydrolase superfamily. PpaX family%3B KEGG: bli:BL03404 pyrophosphatase PpaX gene gene3903 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03904 S100027_03905 S100027_03905 S100027_03905 3687808 3688755 - putative membrane protein YvoD Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3904 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03905 S100027_03906 S100027_03906 umpA umpA 3688781 3689593 - Prolipoprotein diacylglyceryl transferase Cell membrane%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins%3B Belongs to the Lgt family%3B KEGG: bli:BL03402 phosphatidylglycerol:prolipoprotein diacylglycerol transferase%3B Transferases gene gene3905 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03906 S100027_03907 S100027_03907 hprK hprK 3689605 3690537 - HPr kinase/phosphorylase ATP-binding%3B Carbohydrate metabolism%3B Kinase%3B Magnesium%3B Metal-binding%3B Multifunctional enzyme%3B Nucleotide-binding%3B Serine/threonine-protein kinase%3B Transferase%3B Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr%2C a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing%2C inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites%2C which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose%2C fructose%2C etc.) in the growth medium. Also phosphorylates/dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore%2C by controlling the phosphorylation state of HPr and crh%2C HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR)%2C and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion%3B Belongs to the HPrK/P family%3B KEGG: bsu:BSU35000 HPr kinase/phosphorylase%3B Protein-serine/threonine kinases gene gene3906 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03907 S100027_03908 S100027_03908 S100027_03908 3690720 3691199 + putative HTH-type transcriptional regulator YfiV DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH marR-type DNA-binding domain gene gene3907 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03908 S100027_03909 S100027_03909 S100027_03909 3691339 3692898 + putative MFS-type transporter YfiU Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily. TCR/Tet family gene gene3908 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03909 S100027_03910 S100027_03910 S100027_03910 3692916 3696905 - uncharacterized protein Signal. gene gene3909 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03910 S100027_03911 S100027_03911 S100027_03911 3697003 3697362 - putative membrane protein YvlD Cell membrane%3B Membrane%3B Signal%3B Transmembrane%3B Transmembrane helix. gene gene3910 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03911 S100027_03912 S100027_03912 S100027_03912 3697359 3697559 - putative membrane protein YvlC Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3911 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03912 S100027_03913 S100027_03913 S100027_03913 3697564 3698658 - uncharacterized protein Coiled coil. gene gene3912 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03913 S100027_03914 S100027_03914 S100027_03914 3698684 3699010 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3913 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03914 S100027_03915 S100027_03915 S100027_03915 3699225 3699455 + uncharacterized protein gene gene3914 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03915 S100027_03916 S100027_03916 S100027_03916 3699688 3699831 - Virulence protein Virulence%3B Is critically involved in promoting the replication of S. typhimurium cells inside host macrophages%2C suggesting a role in the establishment of bacterial colonization within macrophages. May be involved in the biosynthesis and modification of the peptidoglycan layer of the cell wall gene gene3915 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03916 S100027_03917 S100027_03917 S100027_03917 3699975 3701249 - UvrABC system protein ATP-binding%3B Cytoplasm%3B DNA damage%3B DNA excision%3B DNA repair%3B DNA-binding%3B Excision nuclease%3B Metal-binding%3B Nucleotide-binding%3B Repeat%3B SOS response%3B Zinc%3B Zinc-finger%3B The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB%2C the UvrA molecules dissociate%3B Belongs to the ABC transporter superfamily. UvrA family%3B Contains 2 ABC transporter domains gene gene3916 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03917 S100027_03918 S100027_03918 S100027_03918 3701333 3702847 - UvrABC system protein ATP-binding%3B Cytoplasm%3B DNA damage%3B DNA excision%3B DNA repair%3B DNA-binding%3B Excision nuclease%3B Metal-binding%3B Nucleotide-binding%3B Repeat%3B SOS response%3B Zinc%3B Zinc-finger%3B The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB%2C the UvrA molecules dissociate%3B Belongs to the ABC transporter superfamily. UvrA family%3B Contains 2 ABC transporter domains gene gene3917 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03918 S100027_03919 S100027_03919 S100027_03919 3702855 3704840 - UvrABC system protein ATP-binding%3B Cytoplasm%3B DNA damage%3B DNA excision%3B DNA repair%3B Excision nuclease%3B Nucleotide-binding%3B SOS response%3B The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site%2C the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix%2C facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found%2C the DNA wraps around the other UvrB subunit that will check the other stand for damage%3B Belongs to the UvrB family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B Contains 1 UVR domain gene gene3918 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03919 S100027_03920 S100027_03920 S100027_03920 3705024 3705257 - Protein CsbA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3919 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03920 S100027_03921 S100027_03921 S100027_03921 3705376 3705669 - hypothetical protein gene gene3920 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03921 S100027_03922 S100027_03922 S100027_03922 3705794 3707029 - Cell division topological determinant MinJ Cell cycle%3B Cell division%3B Cell membrane%3B Membrane%3B Septation%3B Transmembrane%3B Transmembrane helix%3B The main function of the Min system is to promote the disassembly of the cytokinetic ring after cell division%2C thereby ensuring that division occurs only once per cell cycle. MinJ acts as a bridge between DivIVA and MinD. May modulate activity and localization of MinD and MinC through direct interaction with MinD%3B Belongs to the MinJ family%3B Contains 1 PDZ (DHR) domain gene gene3921 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03922 S100027_03923 S100027_03923 S100027_03923 3707303 3707656 - Swarming motility protein SwrAA Cytoplasm%3B Required for swarm cell differentiation. Plays a crucial role in regulating the degree of cell flagellation gene gene3922 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03923 S100027_03924 S100027_03924 S100027_03924 3708009 3709448 - C-terminal processing peptidase Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Serine protease%3B Transmembrane%3B Transmembrane helix%3B Belongs to the peptidase S41A family%3B Contains 1 PDZ (DHR) domain%3B KEGG: bli:BL03390 carboxyl-terminal processing protease gene gene3923 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03924 S100027_03925 S100027_03925 ttuC ttuC 3709578 3710687 - Tartrate dehydrogenase Lyase%3B NAD%3B Oxidoreductase%3B Belongs to the isocitrate and isopropylmalate dehydrogenases family%3B KEGG: bli:BL03389 tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase gene gene3924 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03925 S100027_03926 S100027_03926 S100027_03926 3710792 3712042 - Golgin IMH1 Coiled coil%3B Cytoplasm%3B Golgi apparatus%3B Membrane%3B Protein transport%3B Transport%3B Involved in vesicular transport between an endosomal compartment and the Golgi apparatus%3B Contains 1 GRIP domain gene gene3925 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03926 S100027_03927 S100027_03927 S100027_03927 3712135 3713034 - Cell division protein FtsX Cell cycle%3B Cell division%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. May act as an importer%2C possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation. Acts upstream of the histidine kinases KinA%2C KinB and KinC%2C the RapA phosphatase and the Spo0A sporulation protein%3B Belongs to the ABC-4 integral membrane protein family. FtsX subfamily gene gene3926 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03927 S100027_03928 S100027_03928 S100027_03928 3713018 3713704 - Cell division ATP-binding protein FtsE ATP-binding%3B Cell cycle%3B Cell division%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter FtsEX involved in sporulation. May act as an importer%2C possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation. Acts upstream of the histidine kinases KinA%2C KinB and KinC%2C the RapA phosphatase and the Spo0A sporulation protein%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene3927 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03928 S100027_03929 S100027_03929 S100027_03929 3714057 3714383 - Cytochrome c-551 Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Lipoprotein%3B Membrane%3B Metal-binding%3B Palmitate%3B Signal%3B Transport%3B Electron carrier protein%3B Contains 1 cytochrome c domain gene gene3928 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03929 S100027_03930 S100027_03930 S100027_03930 3714432 3715286 - UPF0750 membrane protein YvjA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0750 family gene gene3929 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03930 S100027_03931 S100027_03931 S100027_03931 3715487 3716470 - Peptide chain release factor Cytoplasm%3B Methylation%3B Protein biosynthesis%3B Ribosomal frameshifting%3B Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. Belongs to the prokaryotic/mitochondrial release factor family gene gene3930 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03931 S100027_03932 S100027_03932 S100027_03932 3716651 3719176 - Protein translocase subunit SecA ATP-binding%3B Cell membrane%3B Cytoplasm%3B Membrane%3B Metal-binding%3B Nucleotide-binding%3B Protein transport%3B Translocation%3B Transport%3B Zinc%3B Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane%2C serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane%3B Belongs to the SecA family gene gene3931 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03932 S100027_03933 S100027_03933 S100027_03933 3719337 3719897 - uncharacterized protein Belongs to the ribosomal protein S30Ae family gene gene3932 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03933 S100027_03934 S100027_03934 S100027_03934 3720124 3720501 - uncharacterized protein gene gene3933 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03934 S100027_03935 S100027_03935 S100027_03935 3720511 3720852 - Flagellar protein FliT Bacterial flagellum biogenesis%3B Chaperone%3B Coiled coil%3B Cytoplasm%3B May act as an export chaperone for the filament capping protein FliD%3B Belongs to the bacillales FliT family gene gene3934 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03935 S100027_03936 S100027_03936 S100027_03936 3720852 3721253 - Flagellar protein FliS Bacterial flagellum biogenesis%3B Cytoplasm%3B Belongs to the FliS family gene gene3935 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03936 S100027_03937 S100027_03937 S100027_03937 3721275 3722756 - Flagellar hook-associated protein Bacterial flagellum%3B Coiled coil%3B Secreted%3B Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure%2C which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end (By similarity)%3B Belongs to the FliD family gene gene3936 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03937 S100027_03938 S100027_03938 S100027_03938 3722775 3723116 - uncharacterized protein gene gene3937 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03938 S100027_03939 S100027_03939 S100027_03939 3723301 3724122 - Flagellin Bacterial flagellum%3B Cell wall%3B Secreted%3B Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Belongs to the bacterial flagellin family gene gene3938 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03939 S100027_03940 S100027_03940 S100027_03940 3724256 3724480 - Carbon storage regulator like protein RNA-binding%3B Could accelerate the degradation of some genes transcripts potentially through selective RNA binding%3B Belongs to the CsrA family gene gene3939 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03940 S100027_03941 S100027_03941 S100027_03941 3724474 3724908 - Flagellar assembly factor FliW Bacterial flagellum biogenesis%3B Cytoplasm%3B Binds to the C-terminal region of flagellin%2C which is implicated in polymerization%2C and participates in the assembly of the flagellum%3B Belongs to the FliW family gene gene3940 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03941 S100027_03942 S100027_03942 S100027_03942 3724927 3725493 - uncharacterized protein gene gene3941 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03942 S100027_03943 S100027_03943 S100027_03943 3725543 3726454 - Flagellar hook-associated protein Bacterial flagellum%3B Secreted%3B Belongs to the bacterial flagellin family gene gene3942 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03943 S100027_03944 S100027_03944 S100027_03944 3726465 3727988 - Flagellar hook-associated protein Bacterial flagellum%3B Secreted%3B Belongs to the flagella basal body rod proteins family gene gene3943 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03944 S100027_03945 S100027_03945 S100027_03945 3728004 3728480 - uncharacterized protein Bacterial flagellum biogenesis%3B Phosphoprotein. gene gene3944 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03945 S100027_03946 S100027_03946 S100027_03946 3728499 3728765 - Negative regulator of flagellin synthesis Bacterial flagellum biogenesis%3B Repressor%3B Transcription%3B Transcription regulation%3B Allows the coupling of early and late flagellar synthesis through the repression of RNA polymerase sigma-D factor- dependent transcription. Belongs to the FlgM family gene gene3945 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03946 S100027_03947 S100027_03947 S100027_03947 3728845 3729264 - uncharacterized protein Bacterial flagellum biogenesis%3B May be involved in the assembly%2C structure%2C or function of the flagellum. May polymerize to form a filamentous structure that is part of the flagellum. To S. typhimurium FliF gene gene3946 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03947 S100027_03948 S100027_03948 S100027_03948 3730014 3730298 - ComF operon protein Competence. gene gene3947 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03948 S100027_03949 S100027_03949 S100027_03949 3730353 3731747 - ComF operon protein ATP-binding%3B Competence%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Involved in transformation (competence for DNA uptake). Required for DNA uptake but not for binding. May provide the driving force for transport of DNA through an aqueous channel. Belongs to the helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain gene gene3948 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03949 S100027_03950 S100027_03950 S100027_03950 3731868 3732710 - DegV domain-containing protein Lipid-binding%3B May bind long-chain fatty acids%2C such as palmitate%2C and may play a role in lipid transport or fatty acid metabolism%3B Contains 1 DegV domain gene gene3949 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03950 S100027_03951 S100027_03951 S100027_03951 3732830 3733519 - Transcriptional regulatory protein DegU Activator%3B Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Repressor%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system DegS/DegU%2C which plays an important role in the transition growth phase. Involved in the control of expression of different cellular functions%2C including production of degradative enzymes such as the neutral and alkaline proteases%2C flagellum formation%2C biofilm formation%2C and competence for DNA uptake. Positively or negatively regulates expression of many different genes. The phosphorylated form is required for synthesis of degradative enzymes%2C flagellum formation and biofilm formation. The unphosphorylated form is required for expression of genetic competence%2C via induction of comK%3B Contains 1 HTH luxR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3950 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03951 S100027_03952 S100027_03952 degS degS 3733601 3734758 - Histidine kinase ATP-binding%3B Coiled coil%3B Cytoplasm%3B Hydrolase%3B Kinase%3B Nucleotide-binding%3B Phosphoprotein%3B Protein phosphatase%3B Transferase%3B Two-component regulatory system%3B Member of the two-component regulatory system DegS/DegU%2C which plays an important role in the transition growth phase. Involved in the control of expression of different cellular functions%2C including production of degradative enzymes such as the neutral and alkaline proteases%2C flagellum formation and biofilm formation. Acts as both a protein kinase that undergoes autophosphorylation and subsequently transfers the phosphate to DegU%2C and a protein phosphatase that dephosphorylates phospho- DegU%3B Contains 1 histidine kinase domain%3B KEGG: bli:BL03360 two-component system%2C NarL family%2C sensor histidine kinase DegS gene gene3951 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03952 S100027_03953 S100027_03953 S100027_03953 3734972 3735610 + Xaa-Pro dipeptidase Belongs to the IMPACT family%3B KEGG: sph:MGAS10270_Spy1444 Xaa-Pro dipeptidase gene gene3952 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03953 S100027_03954 S100027_03954 S100027_03954 3735625 3736698 + Putative transcriptional regulator YvhJ Cell membrane%3B Membrane%3B Signal-anchor%3B Transcription%3B Transcription regulation%3B Transmembrane%3B Transmembrane helix%3B Belongs to the LytR/CpsA/Psr regulatory protein family gene gene3953 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03954 S100027_03955 S100027_03955 S100027_03955 3736783 3737157 - uncharacterized protein gene gene3954 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03955 S100027_03956 S100027_03956 wecA wecA 3737277 3738341 - UDP-N-acetylglucosamine--undecaprenyl-phosphateN-acetylglucosaminephosphotransferase Cell membrane%3B Cell wall biogenesis/degradation%3B Glycosyltransferase%3B Magnesium%3B Manganese%3B Membrane%3B Teichoic acid biosynthesis%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to the peptidoglycan of B. subtili%3B may also be involved in teichuronic acid biosynthesis (Probable)%3B Belongs to the glycosyltransferase 4 family%3B KEGG: bli:BL03358 UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase gene gene3955 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03956 S100027_03957 S100027_03957 tuaH tuaH 3738472 3739653 - Putative teichuronic acid biosynthesis glycosyltransferase TuaH Cell wall biogenesis/degradation%3B Glycosyltransferase%3B Stress response%3B Transferase%3B Belongs to the glycosyltransferase group 1 family%3B KEGG: bli:BL03357 teichuronic acid biosynthesis glycosyltransferase TuaH%3B Glycosyltransferases gene gene3956 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03957 S100027_03958 S100027_03958 tuaG tuaG 3739681 3740439 - putative glycosyltransferase Glycosyltransferase%3B Transferase%3B Belongs to the glycosyltransferase 2 family%3B KEGG: bso:BSNT_05412 teichuronic acid biosynthesis glycosyltransferase TuaG%3B Glycosyltransferases gene gene3957 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03958 S100027_03959 S100027_03959 S100027_03959 3740469 3741143 - Teichuronic acid biosynthesis protein TuaF Cell membrane%3B Cell wall biogenesis/degradation%3B Membrane%3B Stress response%3B Transmembrane%3B Transmembrane helix. gene gene3958 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03959 S100027_03960 S100027_03960 S100027_03960 3741185 3742639 - Teichuronic acid biosynthesis protein TuaE Cell membrane%3B Cell wall biogenesis/degradation%3B Membrane%3B Stress response%3B Transmembrane%3B Transmembrane helix. gene gene3959 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03960 S100027_03961 S100027_03961 S100027_03961 3742703 3743632 - UDP-glucose 4-epimerase Carbohydrate metabolism%3B Galactose metabolism%3B Isomerase%3B NAD%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: dji:CH75_11130 UDP-glucose 4-epimerase gene gene3960 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03961 S100027_03962 S100027_03962 ugdH ugdH 3743650 3744984 - UDP-glucose 6-dehydrogenase Cell wall biogenesis/degradation%3B Cytoplasm%3B NAD%3B Oxidoreductase%3B Phosphoprotein%3B Stress response%3B Catalyzes the conversion of UDP-glucose into UDP- glucuronate%2C one of the precursors of teichuronic acid. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family%3B KEGG: bso:BSNT_05418 UDPglucose 6-dehydrogenase gene gene3961 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03962 S100027_03963 S100027_03963 tuaC tuaC 3745179 3746357 - Putative teichuronic acid biosynthesis glycosyltransferase TuaC Cell wall biogenesis/degradation%3B Glycosyltransferase%3B Stress response%3B Transferase%3B Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: bsu:BSU35590 teichuronic acid biosynthesis glycosyltransferase TuaC%3B Glycosyltransferases gene gene3962 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03963 S100027_03964 S100027_03964 S100027_03964 3746380 3747819 - Teichuronic acid biosynthesis protein TuaB Cell membrane%3B Cell wall biogenesis/degradation%3B Membrane%3B Stress response%3B Transmembrane%3B Transmembrane helix%3B Might be involved in the translocation of teichuronic acid repeating units from the inner to the outer surface of the membrane. Belongs to the polysaccharide synthase family gene gene3963 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03964 S100027_03965 S100027_03965 S100027_03965 3747843 3748502 - Putative undecaprenyl-phosphate N-acetylgalactosaminyl 1-phosphate transferase Cell membrane%3B Cell wall biogenesis/degradation%3B Glycosyltransferase%3B Membrane%3B Stress response%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Might mediate the very first reaction in teichuronic synthesis%2C i. e. the formation of lipid-linked N-acetylglucosamine. Belongs to the bacterial sugar transferase family gene gene3964 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03965 S100027_03966 S100027_03966 S100027_03966 3748734 3750221 - N-acetylmuramoyl-L-alanine amidase Cell wall%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Repeat%3B Secreted%3B Signal%3B Autolysins are cell wall hydrolases involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella - in particular of its basal body - and sporulation. Has a high affinity for teichoic acid-endowed peptidoglycan. LytC is required for efficient swarming motility but not at the level of cell separation or flagellum biosynthesis. Rather%2C LytC appears to be important for proper flagellar function%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B KEGG: bli:BL03348 N-acetylmuramoyl-L-alanine amidase gene gene3965 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03966 S100027_03967 S100027_03967 S100027_03967 3750306 3752450 - N-acetylmuramoyl-L-alanine amidase Cell membrane%3B Cell wall%3B Cell wall biogenesis/degradation%3B Membrane%3B Repeat%3B Secreted%3B Signal%3B KEGG: csq:CSCA_5254 N-acetylmuramoyl-L-alanine amidase gene gene3966 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03967 S100027_03968 S100027_03968 S100027_03968 3752480 3752800 - Membrane-bound protein LytA Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal. gene gene3967 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03968 S100027_03969 S100027_03969 S100027_03969 3752998 3753918 + Transcriptional regulator LytR Cell membrane%3B Membrane%3B Signal-anchor%3B Transcription%3B Transcription regulation%3B Transmembrane%3B Transmembrane helix%3B Attenuator role for operon expression%3B Belongs to the LytR/CpsA/Psr regulatory protein family gene gene3968 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03969 S100027_03970 S100027_03970 wecB wecB 3754158 3755300 - UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) Cell wall biogenesis/degradation%3B Cytoplasm%3B Isomerase%3B Teichoic acid biosynthesis%3B Catalyzes the conversion of UDP-N-acetylglucosamine into UDP-N-acetylmannosamine%2C a precursor of the teichoic acid linkage unit%3B Belongs to the UDP-N-acetylglucosamine 2-epimerase family%3B KEGG: cfu:CFU_3660 UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) gene gene3969 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03970 S100027_03971 S100027_03971 ugp2 ugp2 3755677 3756555 + UTP--glucose-1-phosphate uridylyltransferase Capsule biogenesis/degradation%3B Exopolysaccharide synthesis%3B Nucleotidyltransferase%3B Transferase%3B Belongs to the UDPGP type 2 family%3B KEGG: pmr:PMI1490 UTP--glucose-1-phosphate uridylyltransferase gene gene3970 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03971 S100027_03972 S100027_03972 tagH tagH 3756626 3757537 - Teichoic-acid-transporting ATPase ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Teichoic acids exporter (TC 3. A. 1. 104. 1) family%3B Contains 1 ABC transporter domain%3B KEGG: bsu:BSU35700 teichoic acid transport system ATP-binding protein gene gene3971 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03972 S100027_03973 S100027_03973 S100027_03973 3757558 3758385 - Teichoic acid translocation permease protein TagG Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex TagGH (TC 3. A. 1. 34. 1) involved in exporting the two types of intracellularly synthesized teichoic acids. Probably responsible for the translocation of the substrate across the membrane. Belongs to the ABC-2 integral membrane protein family%3B Contains 1 ABC transmembrane type-2 domain gene gene3972 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03973 S100027_03974 S100027_03974 S100027_03974 3758729 3760042 + hypothetical protein gene gene3973 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03974 S100027_03975 S100027_03975 tagF tagF 3760387 3762963 - CDP-glycerol glycerophosphotransferase Cell membrane%3B Cell wall biogenesis/degradation%3B Glycosyltransferase%3B Membrane%3B Teichoic acid biosynthesis%3B Transferase%3B Catalyzes the addition of a second single glycerol-P residue to the prenolpyrophosphate-linked disaccharide%2C to complete the linkage unit%3B Belongs to the CDP-glycerol glycerophosphotransferase family%3B KEGG: bso:BSNT_05451 CDP-glycerol glycerophosphotransferase gene gene3974 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03975 S100027_03976 S100027_03976 S100027_03976 3763275 3765410 - CDP-glycerol glycerophosphotransferase Cell membrane%3B Cell wall biogenesis/degradation%3B Glycosyltransferase%3B Membrane%3B Teichoic acid biosynthesis%3B Transferase%3B Is responsible for the polymerization of the main chain of the major teichoic acid by sequential transfer of glycerol phosphate units from CDP-glycerol to the disaccharide linkage unit. Synthesizes polymers of approximately 35 glycerol phosphate units in length%3B Belongs to the CDP-glycerol glycerophosphotransferase family%3B KEGG: bli:BL02463 CDP-glycerol glycerophosphotransferase gene gene3975 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03976 S100027_03977 S100027_03977 tagD tagD 3765552 3765947 - Glycerol-3-phosphate cytidylyltransferase Cell wall biogenesis/degradation%3B Cobalt%3B Cytoplasm%3B Iron%3B Magnesium%3B Manganese%3B Nucleotidyltransferase%3B Teichoic acid biosynthesis%3B Transferase%3B Provides activated glycerol phosphate for teichoic acid synthesis%2C via incorporation into both the linkage unit and the teichoic acid polymer by TagB and TagF. Belongs to the cytidylyltransferase family%3B KEGG: ecc:c3696 glycerol-3-phosphate cytidylyltransferase gene gene3976 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03977 S100027_03978 S100027_03978 tagA tagA 3766303 3767085 + N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase Cell wall biogenesis/degradation%3B Glycosyltransferase%3B Secreted%3B Teichoic acid biosynthesis%3B Transferase%3B Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol%2C a key lipid intermediate in the de novo synthesis of teichoic acid%3B Belongs to the glycosyltransferase 26 family%3B KEGG: bso:BSNT_05454 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase gene gene3977 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03978 S100027_03979 S100027_03979 tarL tarL 3767105 3768268 + CDP-ribitol ribitolphosphotransferase Cell membrane%3B Cell wall biogenesis/degradation%3B Glycosyltransferase%3B Membrane%3B Teichoic acid biosynthesis%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the addition of a first single glycerol-P residue to the prenolpyrophosphate-linked disaccharide%3B Belongs to the CDP-glycerol glycerophosphotransferase family%3B KEGG: bsl:A7A1_1141 CDP-ribitol ribitolphosphotransferase gene gene3978 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03979 S100027_03980 S100027_03980 S100027_03980 3768297 3770927 - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Cell wall%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Repeat%3B Secreted%3B Signal%3B Cell wall hydrolase not involved in cell autolysis%2C competence%2C sporulation or germination. It hydrolyzes the beta-1%2C4 glycan bond between the N-acetylglucosaminyl and the N- acetylmuramoyl residues in the glycan chain%3B Belongs to the glycosyl hydrolase 73 family%3B Contains 3 SPOR domains%3B KEGG: bli:BL02465 mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase gene gene3979 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03980 S100027_03981 S100027_03981 S100027_03981 3771056 3772006 - Mannose-6-phosphate isomerase Carbohydrate metabolism%3B Isomerase%3B Metal-binding%3B Zinc%3B Belongs to the mannose-6-phosphate isomerase type 1 family%3B KEGG: bsu:BSU35790 mannose-6-phosphate isomerase gene gene3980 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03981 S100027_03982 S100027_03982 nrdG nrdG 3772162 3772674 - [Formate-C-acetyltransferase]-activating enzyme 4Fe-4S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase%3B S-adenosyl-L-methionine%3B Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical%2C using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. Belongs to the organic radical-activating enzymes family%3B KEGG: bld:BLi03823 anaerobic ribonucleoside-triphosphate reductase activating protein gene gene3981 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03982 S100027_03983 S100027_03983 nrdD nrdD 3772623 3774491 - Ribonucleoside-triphosphate reductase Metal-binding%3B Organic radical%3B Oxidoreductase%3B Zinc%3B Belongs to the anaerobic ribonucleoside-triphosphate reductase family%3B Contains 1 glycine radical domain%3B KEGG: bli:BL02468 ribonucleoside-triphosphate reductase gene gene3982 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03983 S100027_03984 S100027_03984 S100027_03984 3774659 3775645 - 2-keto-3-deoxygluconate permease Cell membrane%3B Membrane%3B Sugar transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell%2C where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)%3B Belongs to the KdgT transporter family gene gene3983 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03984 S100027_03985 S100027_03985 S100027_03985 3775730 3776344 - 2-dehydro-3-deoxy-phosphogluconate aldolase Cytoplasm%3B Lyase%3B Multifunctional enzyme%3B Schiff base%3B Belongs to the KHG/KDPG aldolase family%3B KEGG: bli:BL02470 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase gene gene3984 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03985 S100027_03986 S100027_03986 kdgK kdgK 3776350 3777315 - 2-dehydro-3-deoxygluconokinase ATP-binding%3B Carbohydrate metabolism%3B Kinase%3B Nucleotide-binding%3B Plasmid%3B Transferase%3B Involved in the degradation of glucose via the semi- phosphorylative Entner-Doudoroff pathway. Catalyzes the phosphorylation of 2-keto-3-deoxygluconate (KDG) to produce 2- keto-3-deoxy-6-phosphogluconate (KDPG)%3B Belongs to the carbohydrate kinase pfkB family%3B KEGG: bma:BMA0961 2-dehydro-3-deoxygluconokinase gene gene3985 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03986 S100027_03987 S100027_03987 S100027_03987 3777418 3778434 - putative HTH-type transcriptional regulator EndR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Putative repressor of the endoglucanase operon. Contains 1 HTH lacI-type DNA-binding domain gene gene3986 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03987 S100027_03988 S100027_03988 kduI kduI 3778690 3779517 + 5-dehydro-4-deoxy-D-glucuronate isomerase Isomerase%3B Metal-binding%3B Zinc%3B Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2%2C5-hexodiulosonate%3B Belongs to the KduI family%3B KEGG: cja:CJA_0169 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase gene gene3987 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03988 S100027_03989 S100027_03989 kduD kduD 3779533 3780297 + 2-deoxy-D-gluconate 3-dehydrogenase NAD%3B Oxidoreductase%3B Catalyzes the reversible reduction of 2%2C5-diketo-3- deoxygluconate (DKII or 4%2C6-dihydroxy-2%2C5-dioxohexanoate) into 2- keto-3-deoxygluconate (KDG or 2-dehydro-3-deoxygluconate) with a concomitant oxidation of NADH (Ref. 4). To a lesser extent%2C can also reduce 5-keto-D-gluconate and oxidize D-gluconate and 1%2C2- propanediol (PubMed:24509771). Together with KduI%2C seems to play a role in the catabolism of hexuronates under osmotic stress conditions%2C substituting for the regular hexuronate degrading enzymes UxaABC and UxuAB whose expression is repressed in these conditions (PubMed:23437267). In vitro%2C also exhibits NADH- dependent 20-ketosteroid reductase activity against eukaryotic steroid hormone 11-deoxycorticosterone (11-DOC)%2C which is converted into the product 4-pregnen-20%2C21-diol-3-one. In addition to 11-DOC%2C five other C21 steroid compounds (11-deoxycortisol%2C cortisol%2C corticosterone%2C cortisone%2C and 21-hydroxypregnenolone) are reduced by KduD%2C but steroids lacking the hydroxyl group at C21 position%2C such as pregnenolone%2C testosterone propionate%2C cortisone acetate%2C or progesterone%2C cannot be used as substrate (PubMed:24509771)%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bli:BL02435 2-deoxy-D-gluconate 3-dehydrogenase gene gene3988 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03989 S100027_03990 S100027_03990 frmA frmA 3780338 3781471 - S-(hydroxymethyl)glutathione dehydrogenase Metal-binding%3B Oxidoreductase%3B Zinc%3B Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily%3B KEGG: bsu:BSU26970 S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase gene gene3989 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03990 S100027_03991 S100027_03991 S100027_03991 3781613 3781750 + hypothetical protein gene gene3990 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03991 S100027_03992 S100027_03992 S100027_03992 3781802 3783175 - Putative metabolite transport protein YwtG Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene3991 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03992 S100027_03993 S100027_03993 S100027_03993 3783474 3784430 + Putative transcriptional regulator YwtF Cell membrane%3B Membrane%3B Signal-anchor%3B Transcription%3B Transcription regulation%3B Transmembrane%3B Transmembrane helix%3B Belongs to the LytR/CpsA/Psr regulatory protein family gene gene3992 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03993 S100027_03994 S100027_03994 S100027_03994 3784620 3785480 + Putative phosphatase YcsE Hydrolase%3B Magnesium%3B Metal-binding%3B Belongs to the HAD-like hydrolase superfamily. Cof family gene gene3993 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03994 S100027_03995 S100027_03995 S100027_03995 3785531 3786775 - Gamma-DL-glutamyl hydrolase Cell wall%3B Hydrolase%3B Secreted%3B Signal%3B Cleaves%2C in an endo-type manner%2C the gamma-glutamyl bond between D-glutamate and L-glutamate of poly-gamma-glutamate (PGA). Belongs to the peptidase C40 family%3B KEGG: lfu:HR49_15335 peptidoglycan endopeptidase LytF%3B Acting on peptide bonds (peptidases) gene gene3994 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03995 S100027_03996 S100027_03996 S100027_03996 3787232 3787399 - uncharacterized protein Signal. gene gene3995 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03996 S100027_03997 S100027_03997 S100027_03997 3787396 3788565 - Capsule biosynthesis protein CapA Capsule biogenesis/degradation%3B Cell membrane%3B Membrane%3B Plasmid%3B Transmembrane%3B Transmembrane helix%3B Virulence%3B Essential for the synthesis of the polyglutamate capsule of B. anthracis which is one of the principal virulence factors during anthrax infection. May form a polyglutamyl synthetase complex together with proteins CapB and CapC. Belongs to the CapA family gene gene3996 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03997 S100027_03998 S100027_03998 S100027_03998 3788585 3789034 - Capsule biosynthesis protein CapC Capsule biogenesis/degradation%3B Cell membrane%3B Membrane%3B Plasmid%3B Transmembrane%3B Transmembrane helix%3B Virulence. gene gene3997 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03998 S100027_03999 S100027_03999 S100027_03999 3789050 3790231 - PGA synthase CapB Alternative initiation%3B Ligase%3B Catalyzes the biosynthesis of PGA (gamma-polyglutamic acid) from L-glutamate. Both the 44-kDa and the 33-kDa forms are required for PGA synthesis gene gene3998 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_03999 S100027_04000 S100027_04000 S100027_04000 3791026 3792006 + Sucrose operon repressor DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Repressor for the csc operon. Binds D-fructose as an inducer (By similarity)%3B Contains 1 HTH lacI-type DNA-binding domain gene gene3999 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04000 S100027_04001 S100027_04001 rbsK rbsK 3792009 3792890 + Ribokinase ATP-binding%3B Carbohydrate metabolism%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the carbohydrate kinase PfkB family%3B KEGG: hpas:JL26_09640 ribokinase gene gene4000 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04001 S100027_04002 S100027_04002 rbsD rbsD 3792887 3793282 + D-ribose pyranase Carbohydrate metabolism%3B Cytoplasm%3B Isomerase%3B Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose%3B Belongs to the RbsD / FucU family. RbsD subfamily%3B KEGG: cvi:CV_3019 D-ribose pyranase gene gene4001 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04002 S100027_04003 S100027_04003 S100027_04003 3793320 3794801 + Sulfate/thiosulfate import ATP-binding protein CysA ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Sulfate transport%3B Transport%3B Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3. A. 1. 6) family%3B Contains 1 ABC transporter domain gene gene4002 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04003 S100027_04004 S100027_04004 S100027_04004 3794803 3795765 + Ribose transport system permease protein RbsC Cell membrane%3B Membrane%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system for ribose. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily gene gene4003 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04004 S100027_04005 S100027_04005 S100027_04005 3795780 3796694 + D-xylose-binding periplasmic protein Periplasm%3B Signal%3B Sugar transport%3B Transport%3B Involved in the high-affinity D-xylose membrane transport system. Binds with high affinity to xylose (By similarity)%3B Belongs to the bacterial solute-binding protein 2 family gene gene4004 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04005 S100027_04006 S100027_04006 alsD alsD 3796974 3797735 - Acetolactate decarboxylase Acetoin biosynthesis%3B Decarboxylase%3B Lyase%3B Converts acetolactate into acetoin%3B Belongs to the alpha-acetolactate decarboxylase family%3B KEGG: bli:BL02479 acetolactate decarboxylase gene gene4005 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04006 S100027_04007 S100027_04007 S100027_04007 3797788 3799506 - Acetolactate synthase Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B FAD%3B Flavoprotein%3B Magnesium%3B Metal-binding%3B Thiamine pyrophosphate%3B Transferase%3B Belongs to the TPP enzyme family%3B KEGG: bli:BL02480 acetolactate synthase I/II/III large subunit gene gene4006 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04007 S100027_04008 S100027_04008 S100027_04008 3799667 3800545 + HTH-type transcriptional regulator BenM Activator%3B Aromatic hydrocarbons catabolism%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Positive regulator of the ben and cat genes for benzoate degradation. BenM is necessary for ben gene expression but not for expression of the cat genes%2C which can be regulated by CatM. Binds to the inducers cis%2Ccis-muconate and benzoate. Contains 1 HTH lysR-type DNA-binding domain gene gene4007 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04008 S100027_04009 S100027_04009 S100027_04009 3800663 3800995 + hypothetical protein gene gene4008 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04009 S100027_04010 S100027_04010 S100027_04010 3800965 3801825 + putative transposase-like protein DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene4009 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04010 S100027_04011 S100027_04011 S100027_04011 3801922 3803505 - Gamma-glutamyltransferase Acyltransferase%3B Hydrolase%3B Protease%3B Transferase%3B Zymogen%3B Belongs to the gamma-glutamyltransferase family%3B KEGG: bli:BL02481 gamma-glutamyltranspeptidase / glutathione hydrolase gene gene4010 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04011 S100027_04012 S100027_04012 S100027_04012 3803742 3804218 + putative HTH-type transcriptional regulator YwrC DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH asnC-type DNA-binding domain gene gene4011 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04012 S100027_04013 S100027_04013 S100027_04013 3804240 3804824 + putative transporter YwrB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the chromate ion transporter (CHR) (TC 2. A. 51) family gene gene4012 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04013 S100027_04014 S100027_04014 S100027_04014 3804821 3805357 + putative transporter YwrA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the chromate ion transporter (CHR) (TC 2. A. 51) family gene gene4013 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04014 S100027_04015 S100027_04015 S100027_04015 3805455 3806198 - Protein-tyrosine-phosphatase Capsule biogenesis/degradation%3B Exopolysaccharide synthesis%3B Hydrolase%3B Protein phosphatase%3B Required for the biosynthesis of type 1 capsular polysaccharide. Belongs to the CpsB/CapC family%3B KEGG: pfv:Psefu_1694 protein-tyrosine phosphatase gene gene4014 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04015 S100027_04016 S100027_04016 S100027_04016 3806225 3806947 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the CpsC/CapA family gene gene4015 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04016 S100027_04017 S100027_04017 S100027_04017 3807173 3807316 - uncharacterized protein gene gene4016 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04017 S100027_04018 S100027_04018 S100027_04018 3807532 3809130 + uncharacterized protein Coiled coil%3B Metal-binding%3B Zinc%3B Zinc-finger%3B Contains 1 SWIM-type zinc finger gene gene4017 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04018 S100027_04019 S100027_04019 S100027_04019 3809117 3811882 + Non-specific serine/threonine protein kinase ATP-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Belongs to the SNF2/RAD54 helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: stp:Strop_3363 non-specific serine/threonine protein kinase gene gene4018 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04019 S100027_04020 S100027_04020 S100027_04020 3811879 3812025 - hypothetical protein gene gene4019 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04020 S100027_04021 S100027_04021 S100027_04021 3812279 3813157 - Putative phosphatase Hydrolase%3B Magnesium%3B Metal-binding%3B Belongs to the HAD-like hydrolase superfamily. Cof family gene gene4020 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04021 S100027_04022 S100027_04022 S100027_04022 3813173 3813943 - HTH-type transcriptional repressor GlcR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Plays a role in carbon catabolite repression (CCR). Specifically required for transcriptional repression of the levanase operon by glucose but not by other sugars%3B Contains 1 HTH deoR-type DNA-binding domain gene gene4021 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04022 S100027_04023 S100027_04023 fsaB fsaB 3814086 3814751 - Fructose-6-phosphate aldolase Carbohydrate metabolism%3B Cytoplasm%3B Lyase%3B Schiff base%3B Catalyzes the reversible formation of fructose 6- phosphate from dihydroxyacetone and D-glyceraldehyde 3-phosphate via an aldolization reaction%3B Belongs to the transaldolase family. Type 3A subfamily%3B KEGG: bli:BL02486 fructose-6-phosphate aldolase 2%3B Aldehyde-lyases gene gene4022 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04023 S100027_04024 S100027_04024 srlD srlD 3814772 3815557 - Sorbitol-6-phosphate 2-dehydrogenase Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B NADP%3B Oxidoreductase%3B Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products%2C the first reductive step in the elongation cycle of fatty acid biosynthesis%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bli:BL02488 sorbitol-6-phosphate 2-dehydrogenase gene gene4023 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04024 S100027_04025 S100027_04025 srlB srlB 3815572 3815943 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cytoplasm%3B Kinase%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucitol/sorbitol transport. Contains 1 PTS EIIA type-5 domain%3B KEGG: bli:BL02487 PTS system%2C glucitol/sorbitol-specific IIA component gene gene4024 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04025 S100027_04026 S100027_04026 srlE srlE 3815968 3816975 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Kinase%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucitol/sorbitol transport. Contains 1 PTS EIIB type-5 domain%3B KEGG: bli:BL02489 PTS system%2C glucitol/sorbitol-specific IIB component gene gene4025 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04026 S100027_04027 S100027_04027 S100027_04027 3816993 3817541 - Glucitol/sorbitol permease IIC component Cell inner membrane%3B Cell membrane%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in glucitol/sorbitol transport. Contains 1 PTS EIIC type-5 domain gene gene4026 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04027 S100027_04028 S100027_04028 S100027_04028 3817538 3817981 - Glucitol operon activator protein Activator%3B DNA-binding%3B Phosphotransferase system%3B Transcription%3B Transcription regulation. gene gene4027 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04028 S100027_04029 S100027_04029 S100027_04029 3817978 3818940 - Sorbitol operon regulator Activator%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Positively regulates%2C in the presence of L-sorbose%2C and negatively regulates%2C in the absence of L-sorbose%2C the transcription of the sor operon. Belongs to the SorC transcriptional regulatory family gene gene4028 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04029 S100027_04030 S100027_04030 S100027_04030 3819162 3819509 - Single-stranded DNA-binding protein DNA damage%3B DNA recombination%3B DNA repair%3B DNA replication%3B DNA-binding%3B Plays an important role in DNA replication%2C recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism%3B Contains 1 SSB domain gene gene4029 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04030 S100027_04031 S100027_04031 S100027_04031 3819615 3819986 - uncharacterized protein gene gene4030 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04031 S100027_04032 S100027_04032 S100027_04032 3820168 3820581 + uncharacterized protein gene gene4031 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04032 S100027_04033 S100027_04033 S100027_04033 3820622 3821002 - Large-conductance mechanosensitive channel Cell membrane%3B Ion channel%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell%3B Belongs to the MscL family gene gene4032 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04033 S100027_04034 S100027_04034 S100027_04034 3821072 3821506 - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase Cytoplasm%3B Lipid A biosynthesis%3B Lipid biosynthesis%3B Lipid metabolism%3B Lyase%3B Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs%3B Belongs to the thioester dehydratase family. FabZ subfamily%3B KEGG: bli:BL02496 3-hydroxyacyl-(acyl-carrier-protein) dehydratase gene gene4033 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04034 S100027_04035 S100027_04035 S100027_04035 3821700 3822527 - Flagellar hook-basal body complex protein FlhP Bacterial flagellum biogenesis%3B Coiled coil%3B Belongs to the flagella basal body rod proteins family gene gene4034 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04035 S100027_04036 S100027_04036 S100027_04036 3822571 3823410 - Flagellar hook-basal body complex protein FlhO Bacterial flagellum biogenesis%3B Not required for motility. Belongs to the flagella basal body rod proteins family gene gene4035 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04036 S100027_04037 S100027_04037 S100027_04037 3823619 3824620 - MreB-like protein Belongs to the FtsA/MreB family gene gene4036 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04037 S100027_04038 S100027_04038 S100027_04038 3824806 3825081 - Stage III sporulation protein DNA-binding%3B Repressor%3B Sporulation%3B Transcription%3B Transcription regulation%3B This protein regulates the transcription of sigK%2C which encodes mother cell chamber RNA polymerase sigma-factor (sigma K). Contains 1 HTH deoR-type DNA-binding domain gene gene4037 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04038 S100027_04039 S100027_04039 S100027_04039 3825418 3825846 + putative HTH-type transcriptional regulator YwoH DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH marR-type DNA-binding domain gene gene4038 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04039 S100027_04040 S100027_04040 S100027_04040 3825850 3827043 + putative MFS-type transporter YwoG Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene4039 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04040 S100027_04041 S100027_04041 S100027_04041 3827193 3827771 + Undecaprenyl-diphosphate phosphatase Antibiotic resistance%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Membrane%3B Peptidoglycan synthesis%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin%3B Belongs to the BcrC/YbjG family%3B KEGG: bli:BL02453 undecaprenyl-diphosphatase gene gene4040 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04041 S100027_04042 S100027_04042 ppaC ppaC 3827814 3828743 - Inorganic diphosphatase Cytoplasm%3B Hydrolase%3B Manganese%3B Metal-binding%3B Belongs to the PPase class C family%3B KEGG: bsu:BSU40550 manganese-dependent inorganic pyrophosphatase gene gene4041 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04042 S100027_04043 S100027_04043 S100027_04043 3828878 3829699 - putative manganese catalase Calcium%3B Manganese%3B Metal-binding%3B Oxidoreductase%3B Peroxidase%3B Stress response%3B Belongs to the manganese catalase family gene gene4042 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04043 S100027_04044 S100027_04044 S100027_04044 3829829 3830566 + uncharacterized protein gene gene4043 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04044 S100027_04045 S100027_04045 S100027_04045 3830604 3830792 - IMP dehydrogenase CBS domain%3B Repeat%3B Contains 2 CBS domains%3B KEGG: bsu:BSU09230 IMP dehydrogenase gene gene4044 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04045 S100027_04046 S100027_04046 S100027_04046 3830793 3831011 - IMP dehydrogenase CBS domain%3B Repeat%3B Contains 2 CBS domains%3B KEGG: azo:azo1748 IMP dehydrogenase gene gene4045 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04046 S100027_04047 S100027_04047 S100027_04047 3831074 3832030 - Magnesium transport protein CorA Cell membrane%3B Ion transport%3B Magnesium%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mediates influx of magnesium ions%3B Belongs to the CorA metal ion transporter (MIT) (TC 1. A. 35) family gene gene4046 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04047 S100027_04048 S100027_04048 S100027_04048 3832191 3833489 + UPF0053 protein YqhB CBS domain%3B Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0053 family%3B Contains 2 CBS domains%3B Contains 1 DUF21 domain gene gene4047 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04048 S100027_04049 S100027_04049 S100027_04049 3833650 3834861 + Ammonium transporter NrgA Ammonia transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Functions as an ammonium and methylammonium transporter in the absence of glutamine. Required for ammonium utilization at low concentrations or at low pH values%2C when ammonium is the single nitrogen source. Required for binding of NrgB to the membrane%3B Belongs to the ammonia transporter channel (TC 1. A. 11. 2) family gene gene4048 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04049 S100027_04050 S100027_04050 S100027_04050 3834880 3835230 + Nitrogen regulatory PII-like protein Activator%3B Cell membrane%3B Membrane%3B Transcription%3B Transcription regulation%3B Required for full induction of the nrgAB operon under conditions of ammonium limitation%3B Belongs to the P(II) protein family gene gene4049 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04050 S100027_04051 S100027_04051 S100027_04051 3835279 3835851 - Endopeptidase Clp Cytoplasm%3B Hydrolase%3B Protease%3B Serine protease%3B Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins%3B Belongs to the peptidase S14 family%3B KEGG: dma:DMR_28170 ATP-dependent Clp protease%2C protease subunit gene gene4050 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04051 S100027_04052 S100027_04052 S100027_04052 3835865 3836470 - hypothetical protein gene gene4051 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04052 S100027_04053 S100027_04053 S100027_04053 3836607 3837482 - Stage II sporulation protein Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Involved in forespore engulfment and required for anchoring membrane proteins on the forespore side of the septal membrane. Forms a channel with SpoIIIAH that is open on the forespore end and closed (or gated) on the mother cell end. This allows sigma-E-directed gene expression in the mother-cell compartment of the sporangium to trigger the activation of sigma-G forespore-specific gene expression by a pathway of intercellular signaling gene gene4052 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04053 S100027_04054 S100027_04054 S100027_04054 3837675 3838172 + Phosphinothricin acetyltransferase Acyltransferase%3B Antibiotic resistance%3B Herbicide resistance%3B Transferase%3B This enzyme is an effector of phosphinothricin tripeptide (PTT or bialaphos) resistance. Inactivates PTT by transfer of an acetyl group (By similarity)%3B Belongs to the acetyltransferase family. PAT/BAR subfamily%3B Contains 1 N-acetyltransferase domain%3B KEGG: bli:BL04040 phosphinothricin acetyltransferase gene gene4053 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04054 S100027_04055 S100027_04055 S100027_04055 3838220 3838663 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4054 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04055 S100027_04056 S100027_04056 S100027_04056 3838895 3840361 + Major cardiolipin synthase ClsA Cell membrane%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Repeat%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol%3B Belongs to the phospholipase D family. Cardiolipin synthase subfamily%3B Contains 2 PLD phosphodiesterase domains%3B KEGG: bli:BL04039 cardiolipin synthase%3B Transferases for other substituted phosphate groups gene gene4055 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04056 S100027_04057 S100027_04057 S100027_04057 3840501 3841931 + hypothetical protein gene gene4056 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04057 S100027_04058 S100027_04058 S100027_04058 3841962 3843395 - putative transport protein HsrA Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily. EmrB family gene gene4057 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04058 S100027_04059 S100027_04059 S100027_04059 3843388 3843615 - uncharacterized protein gene gene4058 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04059 S100027_04060 S100027_04060 S100027_04060 3843628 3850785 - Dimodular nonribosomal peptide synthase Ligase%3B Phosphopantetheine%3B Phosphoprotein%3B Repeat%3B Specifically adenylates threonine and glycine%2C and loads them onto their corresponding peptidyl carrier domains%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 2 acyl carrier domains gene gene4059 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04060 S100027_04061 S100027_04061 S100027_04061 3850800 3851726 - Isochorismatase Hydrolase%3B Phosphopantetheine%3B Phosphoprotein%3B Belongs to the isochorismatase family%3B Contains 1 acyl carrier domain%3B KEGG: bli:BL04023 bifunctional isochorismate lyase / aryl carrier protein gene gene4060 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04061 S100027_04062 S100027_04062 entE entE 3851751 3853373 - (2%2C3-dihydroxybenzoyl)adenylate synthase ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Activation of the carboxylate group of 2%2C3-dihydroxy- benzoate (DHB)%2C via ATP-dependent PPi exchange reactions%2C to the acyladenylate. Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bli:BL04022 2%2C3-dihydroxybenzoate-AMP ligase gene gene4061 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04062 S100027_04063 S100027_04063 entC entC 3853387 3854577 - Isochorismate synthase Isomerase%3B Phosphoprotein%3B Belongs to the isochorismate synthase family%3B KEGG: bli:BL04021 isochorismate synthase gene gene4062 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04063 S100027_04064 S100027_04064 S100027_04064 3854602 3855372 - 2-deoxy-D-gluconate 3-dehydrogenase Lipid metabolism%3B NADP%3B Oxidoreductase%3B Catalyzes the NADPH-dependent reduction of long chain acyl-CoA (with chain lengths of 14 to 22 carbons) to the corresponding aldehyde%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: yel:LC20_03973 2-deoxy-D-gluconate 3-dehydrogenase gene gene4063 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04064 S100027_04065 S100027_04065 S100027_04065 3855603 3856451 - Ferri-bacillibactin esterase BesA Cytoplasm%3B Hydrolase%3B Serine esterase%3B Catalyzes the hydrolysis of the trilactone cycle of ferri-bacillibactin (ferri-BB) complex%2C leading to the formation of bacillibactin monomers and to cytosolic iron release%2C thus making iron available for metabolic use. Can also hydrolyze bacillibactin (BB)%2C however the catalytic efficiency for ferri-BB hydrolysis is much higher than for BB%3B Belongs to the esterase D family gene gene4064 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04065 S100027_04066 S100027_04066 S100027_04066 3856492 3857511 - Iron-uptake system permease protein FeuC Cell membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the uptake of iron. Probably responsible for the translocation of the substrate across the membrane%3B Part of the ABC transporter complex FeuABC/YusV involved in import of the catecholate siderophores bacillibactin and enterobactin%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene4065 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04066 S100027_04067 S100027_04067 S100027_04067 3857504 3858508 - Iron-uptake system permease protein FeuB Cell membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the uptake of iron. Probably responsible for the translocation of the substrate across the membrane%3B Part of the ABC transporter complex FeuABC/YusV involved in import of the catecholate siderophores bacillibactin and enterobactin%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene4066 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04067 S100027_04068 S100027_04068 S100027_04068 3858526 3859482 - Iron-uptake system-binding protein Cell membrane%3B Cytoplasm%3B Ion transport%3B Iron%3B Iron transport%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B Involved in the uptake of iron%3B Part of the ABC transporter complex FeuABC/YusV involved in import of the catecholate siderophores bacillibactin and enterobactin%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene4067 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04068 S100027_04069 S100027_04069 S100027_04069 3859574 3861169 - HTH-type transcriptional activator Btr Activator%3B Cytoplasm%3B DNA-binding%3B Transcription%3B Transcription regulation%3B In iron-limited conditions%2C activates expression of the feuABCybbA operon%2C which encodes the bacillibactin uptake system. Acts by binding directly to a conserved direct repeat element upstream of the feuA promoter. Activity is increased in the presence of bacillibactin%3B Contains 1 Fe/B12 periplasmic-binding domain%3B Contains 1 HTH araC/xylS-type DNA-binding domain gene gene4068 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04069 S100027_04070 S100027_04070 S100027_04070 3861569 3861889 + uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4069 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04070 S100027_04071 S100027_04071 S100027_04071 3861934 3862575 - uncharacterized protein gene gene4070 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04071 S100027_04072 S100027_04072 S100027_04072 3862650 3863051 - Putative HTH-type transcriptional regulator YwnA DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH rrf2-type DNA-binding domain gene gene4071 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04072 S100027_04073 S100027_04073 S100027_04073 3863223 3863762 + hypothetical protein gene gene4072 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04073 S100027_04074 S100027_04074 S100027_04074 3863643 3864122 - putative membrane protein YwmF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4073 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04074 S100027_04075 S100027_04075 moaA moaA 3864272 3865297 - Cyclic pyranopterin phosphate synthase 4Fe-4S%3B GTP-binding%3B Iron%3B Iron-sulfur%3B Lyase%3B Metal-binding%3B Molybdenum cofactor biosynthesis%3B Nucleotide-binding%3B S-adenosyl-L-methionine%3B Catalyzes%2C together with MoaC%2C the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z)%3B Belongs to the radical SAM superfamily. MoaA family%3B KEGG: bsu:BSU36700 cyclic pyranopterin phosphate synthase gene gene4074 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04075 S100027_04076 S100027_04076 S100027_04076 3865313 3866104 - Protein FdhD like protein Cytoplasm%3B Necessary for formate dehydrogenase activity%3B Belongs to the FdhD family gene gene4075 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04076 S100027_04077 S100027_04077 S100027_04077 3866366 3867628 + putative MFS-type transporter Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene4076 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04077 S100027_04078 S100027_04078 narB narB 3867661 3870012 + Ferredoxin--nitrate reductase 2Fe-2S%3B 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Molybdenum%3B NAD%3B Oxidoreductase%3B Repeat%3B In the C-terminal sectio%3B belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 2Fe-2S ferredoxin-type domain%3B Contains 2 4Fe-4S ferredoxin-type domains%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: pmx:PERMA_0888 ferredoxin-nitrate reductase gene gene4077 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04078 S100027_04079 S100027_04079 S100027_04079 3870059 3870730 - uncharacterized protein Signal%3B Contains 1 VWFA domain%3B To B. subtilis YwmD gene gene4078 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04079 S100027_04080 S100027_04080 S100027_04080 3871124 3871810 - uncharacterized protein Signal%3B Contains 1 VWFA domain%3B To B. subtilis YwmD gene gene4079 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04080 S100027_04081 S100027_04081 S100027_04081 3872128 3873144 - Stage II sporulation protein D Sporulation. gene gene4080 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04081 S100027_04082 S100027_04082 murA murA 3873342 3874652 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Cell cycle%3B Cell division%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Peptidoglycan synthesis%3B Pyruvate%3B Transferase%3B Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine%3B Belongs to the EPSP synthase family. MurA subfamily%3B KEGG: maq:Maqu_2703 UDP-N-acetylglucosamine 1-carboxyvinyltransferase gene gene4081 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04082 S100027_04083 S100027_04083 S100027_04083 3874685 3875428 - uncharacterized protein Signal. gene gene4082 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04083 S100027_04084 S100027_04084 S100027_04084 3875570 3875803 - putative membrane protein YwzB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4083 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04084 S100027_04085 S100027_04085 S100027_04085 3876187 3876582 - ATP synthase epsilon chain ATP synthesis%3B Cell inner membrane%3B Cell membrane%3B CF(1)%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Transport%3B Produces ATP from ADP in the presence of a proton gradient across the membrane%3B Belongs to the ATPase epsilon chain family gene gene4084 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04085 S100027_04086 S100027_04086 atpD atpD 3876606 3878027 - H(+)-transporting two-sector ATPase ATP synthesis%3B ATP-binding%3B Cell membrane%3B CF(1)%3B Hydrogen ion transport%3B Hydrolase%3B Ion transport%3B Membrane%3B Nucleotide-binding%3B Transport%3B Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits%3B Belongs to the ATPase alpha/beta chains family%3B KEGG: bsu:BSU36810 F-type H+-transporting ATPase subunit beta gene gene4085 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04086 S100027_04087 S100027_04087 S100027_04087 3878053 3878907 - ATP synthase gamma chain ATP synthesis%3B Cell inner membrane%3B Cell membrane%3B CF(1)%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Transport%3B Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex%3B Belongs to the ATPase gamma chain family gene gene4086 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04087 S100027_04088 S100027_04088 atpA atpA 3878996 3880504 - H(+)-transporting two-sector ATPase ATP synthesis%3B ATP-binding%3B Cell inner membrane%3B Cell membrane%3B CF(1)%3B Hydrogen ion transport%3B Hydrolase%3B Ion transport%3B Membrane%3B Nucleotide-binding%3B Transport%3B Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit%3B Belongs to the ATPase alpha/beta chains family%3B KEGG: hhm:BN341_p0008 F-type H+-transporting ATPase subunit alpha gene gene4087 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04088 S100027_04089 S100027_04089 S100027_04089 3880512 3881066 - ATP synthase subunit delta ATP synthesis%3B Cell membrane%3B CF(1)%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Transport%3B F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains%2C F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel%2C linked together by a central stalk and a peripheral stalk. During catalysis%2C ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation%3B This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction%3B Belongs to the ATPase delta chain family gene gene4088 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04089 S100027_04090 S100027_04090 S100027_04090 3881063 3881581 - ATP synthase subunit ATP synthesis%3B Cell membrane%3B CF(0)%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains%2C F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel%2C linked together by a central stalk and a peripheral stalk. During catalysis%2C ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation%3B Component of the F(0) channel%2C it forms part of the peripheral stalk%2C linking F(1) to F(0)%3B Belongs to the ATPase B chain family gene gene4089 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04090 S100027_04091 S100027_04091 S100027_04091 3881756 3881968 - ATP synthase subunit ATP synthesis%3B Cell membrane%3B CF(0)%3B Hydrogen ion transport%3B Ion transport%3B Lipid-binding%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains%2C F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel%2C linked together by a central stalk and a peripheral stalk. During catalysis%2C ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation%3B Key component of the F(0) channe%3B it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits%3B Belongs to the ATPase C chain family gene gene4090 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04091 S100027_04092 S100027_04092 S100027_04092 3882018 3882752 - ATP synthase subunit ATP synthesis%3B Cell membrane%3B CF(0)%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Key component of the proton channe%3B it plays a direct role in the translocation of protons across the membrane%3B Belongs to the ATPase A chain family gene gene4091 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04092 S100027_04093 S100027_04093 S100027_04093 3882760 3883143 - ATP synthase protein Cell membrane%3B CF(0)%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex. Belongs to the bacterial AtpI family gene gene4092 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04093 S100027_04094 S100027_04094 uprT uprT 3883544 3884173 - Uracil phosphoribosyltransferase Allosteric enzyme%3B Glycosyltransferase%3B GTP-binding%3B Magnesium%3B Nucleotide-binding%3B Transferase%3B Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate%3B Belongs to the UPRTase family%3B KEGG: bsu:BSU36890 uracil phosphoribosyltransferase gene gene4093 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04094 S100027_04095 S100027_04095 glyA glyA 3884300 3885547 - Glycine hydroxymethyltransferase Amino-acid biosynthesis%3B Cytoplasm%3B One-carbon metabolism%3B Pyridoxal phosphate%3B Transferase%3B Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines%2C thymidylate%2C methionine%2C and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids%2C producing glycine and aldehydes%2C via a retro-aldol mechanism%3B Belongs to the SHMT family%3B KEGG: bsu:BSU36900 glycine hydroxymethyltransferase gene gene4094 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04095 S100027_04096 S100027_04096 S100027_04096 3885773 3886315 - UPF0340 protein Belongs to the UPF0340 family gene gene4095 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04096 S100027_04097 S100027_04097 rpiB rpiB 3886331 3886780 - Ribose-5-phosphate isomerase Isomerase%3B Belongs to the LacAB/RpiB family%3B KEGG: bli:BL03989 ribose 5-phosphate isomerase B gene gene4096 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04097 S100027_04098 S100027_04098 S100027_04098 3886923 3887378 - Protein-tyrosine-phosphatase Hydrolase%3B Protein phosphatase%3B Catalyzes the specific dephosphorylation of phosphoarginine residues in a large number of proteins. Counteracts the protein arginine kinase McsB in vivo. Can dephosphorylate CtsR-%3B thus%2C can restore the DNA-binding ability of the CtsR repressor by reversing the McsB-mediated phosphorylation. Is the only active pArg phosphatase present in B. subtilis. Exhibits almost no activity against pSer%2C pThr%2C or pTyr peptides. Appears to play a role in B. subtilis stress resistance. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes%2C such as protein homeostasis%2C motility%2C competence%2C and stringent and stress responses%2C by regulating gene expression and protein activity%3B Belongs to the low molecular weight phosphotyrosine protein phosphatase family%3B KEGG: bsu:BSU36930 protein-tyrosine phosphatase gene gene4097 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04098 S100027_04099 S100027_04099 S100027_04099 3887529 3888089 - Putative manganese efflux pump MntP Cell membrane%3B Ion transport%3B Manganese%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably functions as a manganese efflux pump%3B Belongs to the MntP (TC 9. B. 29) family gene gene4098 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04099 S100027_04100 S100027_04100 tsaC tsaC 3888164 3889213 - L-threonylcarbamoyladenylate synthase ATP-binding%3B Cytoplasm%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase%3B tRNA processing%3B Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine%2C HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate%2C with the release of diphosphate. Is also able to catalyze the reverse reaction in vitro%2C i. e. the formation of ATP from TC-AMP and PPi%3B Belongs to the SUA5 family%3B Contains 1 YrdC-like domain%3B KEGG: bld:BLi03940 L-threonylcarbamoyladenylate synthase gene gene4099 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04100 S100027_04101 S100027_04101 S100027_04101 3889365 3889772 - uncharacterized protein gene gene4100 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04101 S100027_04102 S100027_04102 S100027_04102 3890152 3890817 - Stage II sporulation protein Sporulation. gene gene4101 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04102 S100027_04103 S100027_04103 S100027_04103 3890937 3892121 - Glucose/mannose transporter GlcP Cell membrane%3B Membrane%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Can transport glucose%2C mannose%2C 2-deoxyglucose and methyl alpha-glucoside%2C but not galactose%3B Belongs to the major facilitator superfamily gene gene4102 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04103 S100027_04104 S100027_04104 ntdC ntdC 3892198 3893244 - Glucose-6-phosphate 3-dehydrogenase Antibiotic biosynthesis%3B NAD%3B Oxidoreductase%3B Involved in the biosynthesis of kanosamine (3-amino-3- deoxy-D-glucose)%2C which is known to have antibiotic and antifungal properties%2C and to be a precursor of the antibiotic neotrehalosadiamine (3%2C3'-diamino-3%2C3'-dideoxy-alpha%2Cbeta- trehalose (NTD)). Catalyzes the oxidation of glucose 6-phosphate to 3-oxo-D-glucose 6-phosphate. It can only use NAD%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: bli:BL03982 glucose-6-phosphate 3-dehydrogenase gene gene4103 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04104 S100027_04105 S100027_04105 ntdB ntdB 3893258 3894106 - Kanosamine-6-phosphate phosphatase Antibiotic biosynthesis%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Involved in the biosynthesis of kanosamine (3-amino-3- deoxy-D-glucose)%2C which is known to have antibiotic and antifungal properties%2C and to be a precursor of the antibiotic neotrehalosadiamine (3%2C3'-diamino-3%2C3'-dideoxy-alpha%2Cbeta- trehalose (NTD)). Catalyzes the dephosphorylation of kanosamine 6- phosphate to yield kanosamine. There is a trace amount of activity using glucosamine-6-phosphate%3B Belongs to the HAD-like hydrolase superfamily. Cof family%3B KEGG: bli:BL03981 kanosamine-6-phosphate phosphatase gene gene4104 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04105 S100027_04106 S100027_04106 ntdA ntdA 3894093 3895406 - 3-dehydro-glucose-6-phosphate--glutamate transaminase Aminotransferase%3B Antibiotic biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Involved in the biosynthesis of kanosamine (3-amino-3- deoxy-D-glucose)%2C which is known to have antibiotic and antifungal properties%2C and to be a precursor of the antibiotic neotrehalosadiamine (3%2C3'-diamino-3%2C3'-dideoxy-alpha%2Cbeta- trehalose (NTD)). Catalyzes the reversible pyridoxal phosphate- dependent transamination of 3-dehydro-alpha-D-glucose 6-phosphate to form alpha-D-kanosamine-6-phosphate. It can only use alpha- anomer and glutamate is the only amino donor%3B Belongs to the DegT/DnrJ/EryC1 family%3B KEGG: bli:BL03980 3-dehydro-glucose-6-phosphate---glutamate transaminase gene gene4105 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04106 S100027_04107 S100027_04107 S100027_04107 3895513 3896502 + NTD biosynthesis operon regulator NtdR Activator%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Positively regulates the ntdABC operon and negatively regulates its own transcription. Binds to NTD to induce ntdABC transcription%3B Contains 1 HTH lacI-type DNA-binding domain gene gene4106 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04107 S100027_04108 S100027_04108 hemK hemK 3896835 3897701 - Peptide chain release factor N(5)-glutamine methyltransferase Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif%3B Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily%3B KEGG: bsu:BSU37000 release factor glutamine methyltransferase gene gene4107 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04108 S100027_04109 S100027_04109 S100027_04109 3897704 3898774 - Peptide chain release factor Cytoplasm%3B Methylation%3B Protein biosynthesis%3B Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA%3B Belongs to the prokaryotic/mitochondrial release factor family gene gene4108 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04109 S100027_04110 S100027_04110 S100027_04110 3898910 3899293 + uncharacterized protein gene gene4109 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04110 S100027_04111 S100027_04111 S100027_04111 3899429 3899989 + Chromosome-anchoring protein RacA Cell cycle%3B Cell division%3B Chromosome partition%3B Coiled coil%3B Cytoplasm%3B DNA-binding%3B Sporulation%3B Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells%2C thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome%2C causing condensation of the chromosome and its remodeling into an elongated%2C anchored structure%3B Belongs to the RacA family gene gene4110 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04111 S100027_04112 S100027_04112 S100027_04112 3900044 3901000 - putative transporter YwkB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the auxin efflux carrier (TC 2. A. 69) family gene gene4111 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04112 S100027_04113 S100027_04113 S100027_04113 3901179 3902882 - Malate dehydrogenase (oxaloacetate-decarboxylating) Metal-binding%3B NAD%3B Oxidoreductase%3B Belongs to the malic enzymes family%3B KEGG: bsu:BSU37050 malate dehydrogenase (oxaloacetate-decarboxylating) gene gene4112 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04113 S100027_04114 S100027_04114 S100027_04114 3903221 3903805 - Thymidine kinase ATP-binding%3B Cytoplasm%3B DNA synthesis%3B Kinase%3B Metal-binding%3B Nucleotide-binding%3B Transferase%3B Zinc%3B Belongs to the thymidine kinase family%3B KEGG: bsu:BSU37060 thymidine kinase gene gene4113 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04114 S100027_04115 S100027_04115 S100027_04115 3903884 3904084 - 50S ribosomal protein L31 Metal-binding%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Zinc%3B Binds the 23S rRNA%3B Belongs to the ribosomal protein L31P family. Type A subfamily gene gene4114 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04115 S100027_04116 S100027_04116 S100027_04116 3904212 3905495 - Transcription termination factor Rho ATP-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B RNA-binding%3B Transcription%3B Transcription regulation%3B Transcription termination%3B Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA%2C activation of Rho's RNA-dependent ATPase activity%2C and release of the mRNA from the DNA template%3B Belongs to the Rho family gene gene4115 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04116 S100027_04117 S100027_04117 glpX glpX 3905957 3906922 - Fructose-bisphosphatase Calvin cycle%3B Carbohydrate metabolism%3B Hydrolase%3B Manganese%3B Metal-binding%3B Catalyzes the hydrolysis of fructose 1%2C6-bisphosphate (Fru 1%2C6-P2) and sedoheptulose 1%2C7-bisphosphate (Sed 1%2C7-P2) to fructose 6-phosphate and sedoheptulose 7-phosphate%2C respectively%3B Belongs to the FBPase class 2 family%3B KEGG: hap:HAPS_0273 fructose-1%2C6-bisphosphatase II gene gene4116 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04117 S100027_04118 S100027_04118 S100027_04118 3906989 3908278 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Cell cycle%3B Cell division%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Peptidoglycan synthesis%3B Pyruvate%3B Transferase%3B Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine%3B Belongs to the EPSP synthase family. MurA subfamily%3B KEGG: bsu:BSU37100 UDP-N-acetylglucosamine 1-carboxyvinyltransferase gene gene4117 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04118 S100027_04119 S100027_04119 talA talA 3908536 3909171 - Transaldolase Cytoplasm%3B Pentose shunt%3B Schiff base%3B Transferase%3B Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway%3B Belongs to the transaldolase family. Type 3B subfamily%3B KEGG: spiu:SPICUR_04415 transaldolase gene gene4118 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04119 S100027_04120 S100027_04120 fbaA fbaA 3909404 3910261 - Fructose-bisphosphate aldolase Glycolysis%3B Lyase%3B Metal-binding%3B Phosphoprotein%3B Sporulation%3B Zinc%3B Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1%2C6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis%3B Belongs to the class II fructose-bisphosphate aldolase family%3B KEGG: bsu:BSU37120 fructose-bisphosphate aldolase%2C class II gene gene4119 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04120 S100027_04121 S100027_04121 S100027_04121 3910464 3910838 - DNA-binding response regulator MtrA DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system MtrA/MtrB%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene4120 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04121 S100027_04122 S100027_04122 S100027_04122 3911015 3911545 + uncharacterized protein gene gene4121 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04122 S100027_04123 S100027_04123 S100027_04123 3911742 3912074 + hypothetical protein gene gene4122 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04123 S100027_04124 S100027_04124 S100027_04124 3912044 3912904 + putative transposase-like protein DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene4123 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04124 S100027_04125 S100027_04125 pyrG pyrG 3912968 3914575 - CTP synthase (glutamine hydrolyzing) ATP-binding%3B Glutamine amidotransferase%3B Ligase%3B Nucleotide-binding%3B Pyrimidine biosynthesis%3B Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen%3B Belongs to the CTP synthase family%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: sbw:TGUWTKB_3070 CTP synthase gene gene4124 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04125 S100027_04126 S100027_04126 S100027_04126 3914830 3915345 - putative DNA-directed RNA polymerase subunit delta DNA-directed RNA polymerase%3B Nucleotidyltransferase%3B Transcription%3B Transferase%3B Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit%2C RNAP displays an increased specificity of transcription%2C a decreased affinity for nucleic acids%2C and an increased efficiency of RNA synthesis because of enhanced recycling%3B Belongs to the RpoE family gene gene4125 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04126 S100027_04127 S100027_04127 S100027_04127 3915647 3916786 - Acyl-CoA dehydrogenase FAD%3B Fatty acid metabolism%3B Flavoprotein%3B Lipid degradation%3B Lipid metabolism%3B Oxidoreductase%3B Involved in the degradation of long-chain fatty acids. Belongs to the acyl-CoA dehydrogenase family%3B KEGG: rme:Rmet_5425 null%3B With other acceptors gene gene4126 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04127 S100027_04128 S100027_04128 S100027_04128 3916808 3917938 - Acyl-CoA dehydrogenase FAD%3B Flavoprotein%3B Oxidoreductase%3B Sporulation%3B Belongs to the acyl-CoA dehydrogenase family%3B KEGG: bli:BL03927 null%3B With other acceptors gene gene4127 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04128 S100027_04129 S100027_04129 paaH paaH 3917951 3918814 - 3-hydroxybutyryl-CoA dehydrogenase Fatty acid metabolism%3B Lipid metabolism%3B NADP%3B Oxidoreductase%3B Belongs to the 3-hydroxyacyl-CoA dehydrogenase family%3B KEGG: bli:BL03926 3-hydroxybutyryl-CoA dehydrogenase gene gene4128 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04129 S100027_04130 S100027_04130 S100027_04130 3918830 3920008 - Acetyl-CoA C-acetyltransferase Acyltransferase%3B Transferase%3B Belongs to the thiolase family%3B KEGG: bli:BL03925 acetyl-CoA C-acetyltransferase gene gene4129 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04130 S100027_04131 S100027_04131 S100027_04131 3920106 3922220 - uncharacterized protein Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Contains 2 4Fe-4S ferredoxin-type domains%3B KEGG: gfo:GFO_1637 null%3B Oxidoreductases gene gene4130 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04131 S100027_04132 S100027_04132 S100027_04132 3922370 3923560 + Minor cardiolipin synthase ClsB Cell membrane%3B Membrane%3B Repeat%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Involved in the biosynthesis of cardiolipin%3B Belongs to the phospholipase D family. Cardiolipin synthase subfamily%3B Contains 2 PLD phosphodiesterase domains%3B KEGG: bli:BL03965 cardiolipin synthase%3B Transferases for other substituted phosphate groups gene gene4131 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04132 S100027_04133 S100027_04133 S100027_04133 3923635 3923901 + uncharacterized protein gene gene4132 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04133 S100027_04134 S100027_04134 rarS rarS 3923986 3925656 - Arginine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: bli:BL03923 arginyl-tRNA synthetase gene gene4133 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04134 S100027_04135 S100027_04135 S100027_04135 3925653 3926147 - putative beta-barrel protein YwiB gene gene4134 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04135 S100027_04136 S100027_04136 speB speB 3926239 3927111 - Agmatinase Hydrolase%3B Manganese%3B Metal-binding%3B Polyamine biosynthesis%3B Putrescine biosynthesis%3B Spermidine biosynthesis%3B Catalyzes the formation of putrescine from agmatine%3B Belongs to the arginase family. Agmatinase subfamily%3B KEGG: bsu:BSU37490 agmatinase gene gene4135 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04136 S100027_04137 S100027_04137 speE speE 3927166 3927996 - Spermidine synthase Cytoplasm%3B Polyamine biosynthesis%3B Spermidine biosynthesis%3B Transferase%3B Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1%2C4-diaminobutane) to yield spermidine%3B Belongs to the spermidine/spermine synthase family%3B Contains 1 PABS (polyamine biosynthesis) domain%3B KEGG: bli:BL03920 spermidine synthase gene gene4136 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04137 S100027_04138 S100027_04138 S100027_04138 3928251 3928973 + hypothetical protein gene gene4137 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04138 S100027_04139 S100027_04139 S100027_04139 3929101 3931176 + Penicillin-binding protein 2D Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Peptidoglycan synthesis%3B Signal-anchor%3B Transmembrane%3B Transmembrane helix%3B Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall%2C the first layer of peptidoglycan synthesized on the surface of the inner forespore membrane%3B In the N-terminal sectio%3B belongs to the glycosyltransferase 51 family%3B In the C-terminal sectio%3B belongs to the transpeptidase family gene gene4138 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04139 S100027_04140 S100027_04140 S100027_04140 3931234 3931749 - uncharacterized protein gene gene4139 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04140 S100027_04141 S100027_04141 S100027_04141 3931762 3932451 - Putative zinc metalloprotease YwhC Cell membrane%3B Hydrolase%3B Membrane%3B Metal-binding%3B Metalloprotease%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Zinc%3B Belongs to the peptidase M50B family gene gene4140 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04141 S100027_04142 S100027_04142 S100027_04142 3932532 3932717 + 2-hydroxymuconate tautomerase Isomerase%3B Belongs to the 4-oxalocrotonate tautomerase family%3B KEGG: bli:BL03961 4-oxalocrotonate tautomerase gene gene4141 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04142 S100027_04143 S100027_04143 S100027_04143 3932761 3933567 - hypothetical protein gene gene4142 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04143 S100027_04144 S100027_04144 S100027_04144 3933754 3934257 - uncharacterized protein gene gene4143 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04144 S100027_04145 S100027_04145 S100027_04145 3934288 3935586 - uncharacterized protein Contains 1 HD domain gene gene4144 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04145 S100027_04146 S100027_04146 S100027_04146 3935826 3936050 - UPF0741 protein Belongs to the UPF0741 family gene gene4145 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04146 S100027_04147 S100027_04147 S100027_04147 3936273 3937058 + Prespore-specific transcriptional regulator RsfA Activator%3B DNA-binding%3B Repressor%3B Sporulation%3B Transcription%3B Transcription regulation%3B Seems to improve the efficiency of sporulation by fine- tuning the expression of genes in the sigma F regulon%2C particularly the timing of their expression. Negatively regulates spoIIR and its own synthesis. Contains 1 Myb-like domain gene gene4146 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04147 S100027_04148 S100027_04148 S100027_04148 3937239 3937568 + uncharacterized protein Membrane%3B Signal%3B Transmembrane%3B Transmembrane helix. gene gene4147 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04148 S100027_04149 S100027_04149 lipL lipL 3937723 3938673 - Octanoyl-[GcvH]:protein N-octanoyltransferase Acyltransferase%3B Transferase%3B Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes%3B Belongs to the octanoyltransferase LipL family%3B Contains 1 BPL/LPL catalytic domain%3B KEGG: bli:BL03912 octanoyl-(GcvH):protein N-octanoyltransferase gene gene4148 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04149 S100027_04150 S100027_04150 pobA pobA 3938670 3939875 - 4-hydroxybenzoate 3-monooxygenase Aromatic hydrocarbons catabolism%3B FAD%3B Flavoprotein%3B Monooxygenase%3B NADP%3B Oxidoreductase%3B KEGG: efe:EFER_4403 p-hydroxybenzoate 3-monooxygenase gene gene4149 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04150 S100027_04151 S100027_04151 S100027_04151 3939891 3941267 - Benzoate transport protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probable uptake of benzoate. Belongs to the major facilitator superfamily. Aromatic acid:H(+) symporter (AAHS) (TC 2. A. 1. 15) family gene gene4150 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04151 S100027_04152 S100027_04152 hpaD hpaD 3941306 3942157 - 3%2C4-dihydroxyphenylacetate 2%2C3-dioxygenase Aromatic hydrocarbons catabolism%3B Dioxygenase%3B Iron%3B Oxidoreductase%3B KEGG: bli:BL03909 3%2C4-dihydroxyphenylacetate 2%2C3-dioxygenase gene gene4151 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04152 S100027_04153 S100027_04153 S100027_04153 3942181 3942372 - 2-hydroxymuconate tautomerase Isomerase%3B Belongs to the 4-oxalocrotonate tautomerase family%3B KEGG: ror:RORB6_15955 4-oxalocrotonate tautomerase gene gene4152 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04153 S100027_04154 S100027_04154 dmpH dmpH 3942390 3943175 - 2-oxo-3-hexenedioate decarboxylase Aromatic hydrocarbons catabolism%3B Lyase%3B Plasmid%3B Belongs to the hydratase/decarboxylase family%3B KEGG: bli:BL03907 2-oxo-3-hexenedioate decarboxylase gene gene4153 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04154 S100027_04155 S100027_04155 dmpC dmpC 3943190 3944674 - Aminomuconate-semialdehyde dehydrogenase Cytoplasm%3B NAD%3B Oxidoreductase%3B Ubl conjugation%3B Involved in ferulic acid and sinapic acid biosynthesis by oxidation of conyferylaldehyde and sinapaldehyde%2C respectively. Can oxidize L-lactaldehyde. Possesses activity on acetaldehyde and glycolaldehyde in vitro%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: bli:BL03906 aminomuconate-semialdehyde/2-hydroxymuconate-6-semialdehyde dehydrogenase gene gene4154 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04155 S100027_04156 S100027_04156 S100027_04156 3944867 3945646 + Glycerol operon regulatory protein Activator%3B DNA-binding%3B Glycerol metabolism%3B Transcription%3B Transcription regulation%3B May be an activator protein for the gylABX operon. Contains 1 HTH iclR-type DNA-binding domain%3B Contains 1 iclR-ED (iclR effector binding) domain gene gene4155 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04156 S100027_04157 S100027_04157 S100027_04157 3945665 3946615 + 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase Decarboxylase%3B Lyase%3B Metal-binding%3B Zinc%3B Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA)%2C a key precursor of NAD%2C and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD%2C ACMS is converted to AMS%2C a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway (By similarity)%3B Belongs to the ACMSD family gene gene4156 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04157 S100027_04158 S100027_04158 S100027_04158 3946659 3947630 - Phosphate acetyltransferase Acyltransferase%3B Cytoplasm%3B Transferase%3B Belongs to the phosphate acetyltransferase and butyryltransferase family%3B KEGG: bsu:BSU37660 phosphate acetyltransferase gene gene4157 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04158 S100027_04159 S100027_04159 S100027_04159 3947920 3948684 + Chlorite O(2)-lyase Heme%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Peroxidase%3B May function as heme-dependent peroxidase%3B Belongs to the UPF0447 family%3B KEGG: bsr:I33_3915 chlorite dismutase gene gene4158 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04159 S100027_04160 S100027_04160 S100027_04160 3948733 3949275 - uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix%3B Required for complex colony architecture gene gene4159 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04160 S100027_04161 S100027_04161 S100027_04161 3949692 3951038 + Ktr system potassium uptake protein Cell membrane%3B Ion transport%3B Membrane%3B Potassium%3B Potassium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Integral membrane subunit of the KtrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress%3B Belongs to the TrkH potassium transport family. Ktr (TC 2. A. 38. 4) subfamily gene gene4160 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04161 S100027_04162 S100027_04162 S100027_04162 3951275 3951802 + Spore coat protein GerQ Germination%3B Isopeptide bond%3B Sporulation%3B Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA gene gene4161 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04162 S100027_04163 S100027_04163 S100027_04163 3951843 3952988 - Putative transport permease YfiN Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the ABC-2 integral membrane protein family%3B Contains 1 ABC transmembrane type-2 domain gene gene4162 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04163 S100027_04164 S100027_04164 S100027_04164 3952990 3954111 - hypothetical protein gene gene4163 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04164 S100027_04165 S100027_04165 S100027_04165 3954128 3955063 - Polyamine-transporting ATPase ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3. A. 1. 11. 1) family%3B Contains 1 ABC transporter domain%3B KEGG: rme:Rmet_4399 spermidine/putrescine transport system ATP-binding protein gene gene4164 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04165 S100027_04166 S100027_04166 S100027_04166 3955167 3956273 - Sensor histidine kinase YfiJ ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system YfiJ/YfiK. Probably activates YfiK by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bcz:BCZK1607 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene4165 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04166 S100027_04167 S100027_04167 cheB cheB 3956288 3956959 - Protein-glutamate methylesterase Chemotaxis%3B Cytoplasm%3B Hydrolase%3B Phosphoprotein%3B Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain%3B KEGG: tbe:Trebr_0103 two-component system%2C chemotaxis family%2C response regulator CheB gene gene4166 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04167 S100027_04168 S100027_04168 S100027_04168 3957085 3957462 - Proline--tRNA ligase Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0382 family%3B KEGG: gsl:Gasu_24190 prolyl-tRNA synthetase gene gene4167 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04168 S100027_04169 S100027_04169 S100027_04169 3957524 3958825 - Putative purine permease YwdJ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2. A. 40) subfamily gene gene4168 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04169 S100027_04170 S100027_04170 S100027_04170 3958865 3959173 - uncharacterized protein gene gene4169 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04170 S100027_04171 S100027_04171 S100027_04171 3959445 3960827 + Aldehyde dehydrogenase (NAD(+)) Acetylation%3B Cytoplasm%3B NAD%3B NADP%3B Oxidoreductase%3B ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids%2C biogenic amines%2C neurotransmitters%2C and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes (By similarity)%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: bli:BL03952 aldehyde dehydrogenase (NAD+) gene gene4170 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04171 S100027_04172 S100027_04172 S100027_04172 3960875 3961552 - Uracil-DNA glycosylase Cytoplasm%3B DNA damage%3B DNA repair%3B Glycosidase%3B Hydrolase%3B Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine%3B Belongs to the uracil-DNA glycosylase family%3B KEGG: bsu:BSU37970 uracil-DNA glycosylase gene gene4171 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04172 S100027_04173 S100027_04173 S100027_04173 3961566 3962384 - putative glycosyltransferase YwdF Glycosyltransferase%3B Transferase%3B Belongs to the glycosyltransferase 2 family gene gene4172 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04173 S100027_04174 S100027_04174 pdxK pdxK 3962622 3963434 + Pyridoxal kinase ATP-binding%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Transferase%3B Phosphorylates B6 vitamer%3B functions in a salvage pathway. Uses pyridoxal%2C pyridoxine%2C and pyridoxamine as substrates. Can also use hydroxymethylpyrimidine (HMP) as substrate%3B Belongs to the ThiD family%3B KEGG: bsu:BSU38020 pyridoxine kinase gene gene4173 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04174 S100027_04175 S100027_04175 S100027_04175 3963468 3963806 - hypothetical protein gene gene4174 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04175 S100027_04176 S100027_04176 sacA sacA 3963823 3965259 - Beta-fructofuranosidase Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Belongs to the glycosyl hydrolase 32 family%3B KEGG: bli:BL03892 beta-fructofuranosidase gene gene4175 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04176 S100027_04177 S100027_04177 S100027_04177 3965277 3966656 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Kinase%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in sucrose transport (By similarity)%3B Acts as both a kinase and a phosphatase on SacT%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bli:BL03890 PTS system%2C sucrose-specific IIB component gene gene4176 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04177 S100027_04178 S100027_04178 S100027_04178 3966902 3967741 - SacPA operon antiterminator Activator%3B Phosphoprotein%3B Repeat%3B RNA-binding%3B Transcription%3B Transcription regulation%3B Mediates positive regulation of the sacPA operon by functioning as an antiterminator factor of transcription. Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains gene gene4177 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04178 S100027_04179 S100027_04179 S100027_04179 3967775 3968065 - hypothetical protein gene gene4178 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04179 S100027_04180 S100027_04180 S100027_04180 3968546 3970966 + Minor extracellular protease vpr Hydrolase%3B Protease%3B Secreted%3B Serine protease%3B Signal%3B Zymogen%3B Not required for growth or sporulation. Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bli:BL03950 minor extracellular serine protease Vpr%3B Serine endopeptidases gene gene4179 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04180 S100027_04181 S100027_04181 S100027_04181 3971090 3971338 + hypothetical protein gene gene4180 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04181 S100027_04182 S100027_04182 S100027_04182 3971335 3972342 - uncharacterized protein To bacterial alkanal monooxygenase alpha and beta chains gene gene4181 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04182 S100027_04183 S100027_04183 S100027_04183 3972429 3972566 + hypothetical protein gene gene4182 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04183 S100027_04184 S100027_04184 S100027_04184 3972595 3973344 - FMN reductase (NADPH) Flavoprotein%3B FMN%3B Luminescence%3B NADP%3B Oxidoreductase%3B Involved in bioluminescence. It is a good supplier of reduced flavin mononucleotide (FMNH2) to the bioluminescence reaction. Belongs to the flavin oxidoreductase frp family%3B KEGG: bli:BL03887 FMN reductase (NADPH) gene gene4183 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04184 S100027_04185 S100027_04185 hipO hipO 3973489 3974664 + Hippurate hydrolase Cobalt%3B Hydrolase%3B Metal-binding%3B Zinc%3B Belongs to the peptidase M20A family%3B KEGG: brh:RBRH_03274 hippurate hydrolase gene gene4184 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04185 S100027_04186 S100027_04186 S100027_04186 3974692 3975861 - Rod shape-determining protein RodA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Required for the maintenance of the rod cell shape. Also essential for the elongation of the lateral wall of the cell%3B Belongs to the SEDS family. RodA subfamily gene gene4185 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04186 S100027_04187 S100027_04187 S100027_04187 3975973 3977157 - Rod shape-determining protein RodA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Required for the maintenance of the rod cell shape. Also essential for the elongation of the lateral wall of the cell%3B Belongs to the SEDS family. RodA subfamily gene gene4186 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04187 S100027_04188 S100027_04188 S100027_04188 3977436 3978791 + uncharacterized protein gene gene4187 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04188 S100027_04189 S100027_04189 S100027_04189 3978781 3978963 - hypothetical protein gene gene4188 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04189 S100027_04190 S100027_04190 S100027_04190 3979215 3979475 + Spore morphoproteinis and germination protein YwcE Cell membrane%3B Germination%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Required for proper spore morphogenesis. Important for spore germination (By similarity)%3B Belongs to the YwcE family gene gene4189 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04190 S100027_04191 S100027_04191 S100027_04191 3979523 3980467 - hypothetical protein gene gene4190 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04191 S100027_04192 S100027_04192 S100027_04192 3980464 3980721 - hypothetical protein gene gene4191 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04192 S100027_04193 S100027_04193 S100027_04193 3980739 3981194 - putative N-acetyltransferase YfmK Acyltransferase%3B Transferase%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain gene gene4192 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04193 S100027_04194 S100027_04194 S100027_04194 3981206 3983014 - ABC transporter B family member 23%2C mitochondrial ATP-binding%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Mitochondrion%3B Mitochondrion inner membrane%3B Nucleotide-binding%3B Transit peptide%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Performs an essential function in the generation of cytoplasmic iron-sulfur proteins by mediating export of Fe/S cluster precursors synthesized by NFS1 and other mitochondrial proteins. Not involved in the export of cyclic pyranopterin monophosphate (cPMP) from mitochondria into the cytosol%3B Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3. A. 1. 210) subfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene4193 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04194 S100027_04195 S100027_04195 S100027_04195 3983008 3984957 - putative anion import ATP-binding protein ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of an ABC transporter complex involved in anions import (Probable). Responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene4194 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04195 S100027_04196 S100027_04196 S100027_04196 3984976 3986976 - Asparagine synthase (glutamine-hydrolyzing) KEGG: blh:BaLi_c40470 asparagine synthase (glutamine-hydrolysing) gene gene4195 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04196 S100027_04197 S100027_04197 S100027_04197 3986973 3987437 - hypothetical protein gene gene4196 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04197 S100027_04198 S100027_04198 S100027_04198 3987437 3987709 - hypothetical protein gene gene4197 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04198 S100027_04199 S100027_04199 S100027_04199 3988060 3988692 - Response regulator GacA Activator%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Involved in the regulation of secondary metabolism. Involved in the synthesis of the antifungal factors cyanide and 2%2C4-diacetylphloroglucinol. Contains 1 HTH luxR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene4198 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04199 S100027_04200 S100027_04200 S100027_04200 3988864 3988980 + hypothetical protein gene gene4199 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04200 S100027_04201 S100027_04201 qoxD qoxD 3989035 3989400 - Menaquinol oxidase (H(+)-transporting) Cell membrane%3B Membrane%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth. Belongs to the cytochrome c oxidase bacterial subunit 4 family%3B KEGG: bli:BL03874 cytochrome aa3-600 menaquinol oxidase subunit IV%3B overlaps another CDS with the same product name gene gene4200 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04201 S100027_04202 S100027_04202 qoxC qoxC 3989400 3990014 - Menaquinol oxidase (H(+)-transporting) Cell membrane%3B Membrane%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth. Belongs to the cytochrome c oxidase subunit 3 family%3B KEGG: bli:BL03873 cytochrome aa3-600 menaquinol oxidase subunit III%3B overlaps another CDS with the same product name gene gene4201 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04202 S100027_04203 S100027_04203 qoxB qoxB 3990029 3991978 - Menaquinol oxidase (H(+)-transporting) Cell membrane%3B Copper%3B Electron transport%3B Heme%3B Hydrogen ion transport%3B Ion transport%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Respiratory chain%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth. Belongs to the heme-copper respiratory oxidase family%3B KEGG: bli:BL03872 cytochrome aa3-600 menaquinol oxidase subunit I gene gene4202 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04203 S100027_04204 S100027_04204 qoxA qoxA 3991996 3992964 - Menaquinol oxidase (H(+)-transporting) Cell membrane%3B Electron transport%3B Lipoprotein%3B Membrane%3B Oxidoreductase%3B Palmitate%3B Respiratory chain%3B Signal%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I. Belongs to the cytochrome c oxidase subunit 2 family%3B KEGG: bld:BLi04040 cytochrome aa3-600 menaquinol oxidase subunit II gene gene4203 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04204 S100027_04205 S100027_04205 S100027_04205 3993436 3994425 - UDP-glucose 4-epimerase Carbohydrate metabolism%3B Galactose metabolism%3B Isomerase%3B NAD%3B Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD (By similarity)%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: ecl:EcolC_3183 UDP-glucose 4-epimerase gene gene4204 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04205 S100027_04206 S100027_04206 S100027_04206 3995227 3995376 + hypothetical protein gene gene4205 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04206 S100027_04207 S100027_04207 S100027_04207 3995547 3995765 - hypothetical protein gene gene4206 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04207 S100027_04208 S100027_04208 S100027_04208 3995918 3996157 + Putative NAD(P)H-dependent FMN-containing oxidoreductase YwqN Flavoprotein%3B FMN%3B NAD%3B NADP%3B Oxidoreductase%3B Putative NADPH-dependent oxidoreductase%3B Belongs to the SsuE family gene gene4207 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04208 S100027_04209 S100027_04209 S100027_04209 3996176 3996487 + Putative NAD(P)H-dependent FMN-containing oxidoreductase YwqN Flavoprotein%3B FMN%3B NAD%3B NADP%3B Oxidoreductase%3B Putative NADPH-dependent oxidoreductase%3B Belongs to the SsuE family gene gene4208 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04209 S100027_04210 S100027_04210 S100027_04210 3996656 3996970 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4209 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04210 S100027_04211 S100027_04211 S100027_04211 3996967 3998505 + putative symporter YwcA Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene4210 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04211 S100027_04212 S100027_04212 xylB xylB 3998558 4000057 - Xylulokinase ATP-binding%3B Carbohydrate metabolism%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Xylose metabolism%3B Belongs to the FGGY kinase family%3B KEGG: sod:Sant_1620 xylulokinase gene gene4211 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04212 S100027_04213 S100027_04213 xylA xylA 4000057 4001403 - Xylose isomerase Carbohydrate metabolism%3B Cytoplasm%3B Isomerase%3B Magnesium%3B Metal-binding%3B Pentose shunt%3B Xylose metabolism%3B Belongs to the xylose isomerase family%3B KEGG: bli:BL03867 xylose isomerase gene gene4212 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04213 S100027_04214 S100027_04214 S100027_04214 4001595 4002758 + Xylose repressor Carbohydrate metabolism%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Xylose metabolism%3B Transcriptional repressor of xylose-utilizing enzymes. Belongs to the ROK (NagC/XylR) family gene gene4213 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04214 S100027_04215 S100027_04215 thiE thiE 4002999 4003673 - Thiamine phosphate synthase Magnesium%3B Metal-binding%3B Thiamine biosynthesis%3B Transferase%3B Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)%3B Belongs to the thiamine-phosphate synthase family%3B KEGG: bli:BL03866 thiamine-phosphate pyrophosphorylase gene gene4214 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04215 S100027_04216 S100027_04216 thiM thiM 4003675 4004484 - Hydroxyethylthiazole kinase ATP-binding%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Thiamine biosynthesis%3B Transferase%3B Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)%3B Belongs to the Thz kinase family%3B KEGG: bli:BL03865 hydroxyethylthiazole kinase gene gene4215 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04216 S100027_04217 S100027_04217 S100027_04217 4004481 4005398 - putative HTH-type transcriptional regulator YwbI DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH lysR-type DNA-binding domain gene gene4216 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04217 S100027_04218 S100027_04218 S100027_04218 4005519 4005788 - uncharacterized protein Coiled coil%3B overlaps another CDS with the same product name gene gene4217 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04218 S100027_04219 S100027_04219 S100027_04219 4005785 4006213 - uncharacterized protein Coiled coil%3B overlaps another CDS with the same product name gene gene4218 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04219 S100027_04220 S100027_04220 S100027_04220 4006688 4007074 + Holin-like protein CidA Cell membrane%3B Cytolysis%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell%2C the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment%2C CidA possibly oligomerizes within the bacterial cell membrane%2C creating lesions that disrupt the proton motive force%2C which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and/or regulating their activity by a possible change in the cell wall pH that results from loss of membrane potential%3B Belongs to the CidA/LrgA family. CidA subfamily gene gene4219 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04220 S100027_04221 S100027_04221 S100027_04221 4007056 4007739 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the YohK (E. coli)/YwbG (IPA-22R) (B. subtilis) family gene gene4220 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04221 S100027_04222 S100027_04222 S100027_04222 4007796 4008080 - hypothetical protein gene gene4221 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04222 S100027_04223 S100027_04223 S100027_04223 4008091 4009557 - Osmoregulated proline transporter OpuE Amino-acid transport%3B Cell membrane%3B Membrane%3B Stress response%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Catalyzes the uptake of extracellular proline under high-osmolarity growth conditions. Essential for the use of proline present in the environment as an osmoprotectant%3B Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene4222 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04223 S100027_04224 S100027_04224 rlmI rlmI 4009656 4010846 - 23S rRNA (cytosine(1962)-C(5))-methyltransferase Cytoplasm%3B Methyltransferase%3B RNA-binding%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B Belongs to the methyltransferase superfamily. RlmI family%3B Contains 1 PUA domain%3B KEGG: bli:BL03857 23S rRNA (cytosine1962-C5)-methyltransferase gene gene4223 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04224 S100027_04225 S100027_04225 S100027_04225 4010989 4011369 + Lactoylglutathione lyase Lyase%3B Belongs to the glyoxalase I family%3B KEGG: bli:BL03939 lactoylglutathione lyase gene gene4224 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04225 S100027_04226 S100027_04226 S100027_04226 4011400 4012347 - Phosphoglycerate dehydrogenase Cytoplasm%3B NAD%3B NADP%3B Oxidoreductase%3B Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate%2C respectively%3B Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily%3B KEGG: blh:BaLi_c40720 D-3-phosphoglycerate dehydrogenase gene gene4225 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04226 S100027_04227 S100027_04227 waaJ waaJ 4012486 4013349 - Lipopolysaccharide glucosyltransferase I Glycosyltransferase%3B Stress response%3B Transferase%3B Belongs to the glycosyltransferase 8 family%3B KEGG: stm:STM3717 UDP-glucose:(galactosyl)LPS alpha-1%2C2-glucosyltransferase gene gene4226 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04227 S100027_04228 S100027_04228 S100027_04228 4013303 4013437 - hypothetical protein gene gene4227 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04228 S100027_04229 S100027_04229 S100027_04229 4013471 4013641 - putative membrane protein YdzP Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4228 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04229 S100027_04230 S100027_04230 ydfH ydfH 4014145 4015308 + Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system YdfH/YdfI. May activate YdfI by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bsu:BSU05410 two-component system%2C NarL family%2C sensor histidine kinase YdfH gene gene4229 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04230 S100027_04231 S100027_04231 S100027_04231 4015301 4015939 + Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon Chemotaxis%3B Cytoplasm%3B Hydrolase%3B Phosphoprotein%3B Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene4230 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04231 S100027_04232 S100027_04232 S100027_04232 4016056 4018230 + Membrane protein YdfJ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family. MmpL subfamily gene gene4231 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04232 S100027_04233 S100027_04233 S100027_04233 4018327 4019067 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4232 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04233 S100027_04234 S100027_04234 S100027_04234 4019162 4020493 - Inner membrane transport protein RhmT Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily. Phthalate permease family gene gene4233 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04234 S100027_04235 S100027_04235 dgoD dgoD 4020555 4021703 - Galactonate dehydratase Lyase%3B Magnesium%3B Metal-binding%3B Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate%3B Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily%3B KEGG: bli:BL03851 galactonate dehydratase gene gene4234 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04235 S100027_04236 S100027_04236 S100027_04236 4021720 4022346 - 2-dehydro-3-deoxy-phosphogluconate aldolase Cytoplasm%3B Lyase%3B Multifunctional enzyme%3B Schiff base%3B Belongs to the KHG/KDPG aldolase family%3B KEGG: bli:BL03850 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase gene gene4235 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04236 S100027_04237 S100027_04237 S100027_04237 4022374 4023327 - 2-dehydro-3-deoxygluconokinase ATP-binding%3B Carbohydrate metabolism%3B Kinase%3B Nucleotide-binding%3B Plasmid%3B Transferase%3B Involved in the degradation of glucose via the semi- phosphorylative Entner-Doudoroff pathway. Catalyzes the phosphorylation of 2-keto-3-deoxygluconate (KDG) to produce 2- keto-3-deoxy-6-phosphogluconate (KDPG)%3B Belongs to the carbohydrate kinase pfkB family%3B KEGG: efe:EFER_3552 2-dehydro-3-deoxygluconokinase gene gene4236 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04237 S100027_04238 S100027_04238 S100027_04238 4023345 4024103 - putative HTH-type transcriptional regulator YagI DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH iclR-type DNA-binding domain%3B Contains 1 iclR-ED (iclR effector binding) domain gene gene4237 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04238 S100027_04239 S100027_04239 S100027_04239 4024333 4025682 + Aminopeptidase YwaD Aminopeptidase%3B Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Secreted%3B Signal%3B Zinc%3B Catalyzes the hydrolysis of a range of N-terminal amino acids%3B Belongs to the peptidase M28 family. M28B subfamily%3B KEGG: bcz:BCZK5056 aminopeptidase%3B Aminopeptidases gene gene4238 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04239 S100027_04240 S100027_04240 S100027_04240 4025906 4027267 - putative MFS-type transporter YwoD Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene4239 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04240 S100027_04241 S100027_04241 S100027_04241 4027268 4027480 - hypothetical protein gene gene4240 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04241 S100027_04242 S100027_04242 S100027_04242 4027939 4028598 - GTP diphosphokinase ATP-binding%3B GTP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Functions as a (p)ppGpp synthase. In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. activities in response to changes in nutritional abundance. YwaC has probably a minor role in stringent response%3B Belongs to the RelA/SpoT family%3B KEGG: bli:BL03845 putative GTP pyrophosphokinase gene gene4241 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04242 S100027_04243 S100027_04243 S100027_04243 4028689 4028850 - hypothetical protein gene gene4242 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04243 S100027_04244 S100027_04244 S100027_04244 4029139 4029288 + putative membrane protein YwzH Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4243 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04244 S100027_04245 S100027_04245 dltA dltA 4029303 4030811 + D-alanine--poly(phosphoribitol) ligase ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp%3B Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily%3B KEGG: bli:BL03934 D-alanine--poly(phosphoribitol) ligase subunit 1 gene gene4244 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04245 S100027_04246 S100027_04246 S100027_04246 4030808 4031965 + Protein DltB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Could be involved in the transport of activated D- alanine through the membrane. Belongs to the membrane-bound acyltransferase family gene gene4245 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04246 S100027_04247 S100027_04247 dltC dltC 4031981 4032217 + D-alanine--poly(phosphoribitol) ligase ATP-binding%3B Cell shape%3B Cell wall biogenesis/degradation%3B Ligase%3B Nucleotide-binding%3B Phosphopantetheine%3B Phosphoprotein%3B Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA%3B Contains 1 acyl carrier domain%3B KEGG: bli:BL03932 D-alanine--poly(phosphoribitol) ligase subunit 2 gene gene4246 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04247 S100027_04248 S100027_04248 S100027_04248 4032217 4033386 + Protein DltD Signal. gene gene4247 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04248 S100027_04249 S100027_04249 S100027_04249 4033558 4034649 + Branched-chain-amino-acid transaminase Amino-acid biosynthesis%3B Aminotransferase%3B Branched-chain amino acid biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Transaminates branched-chain amino acids and ketoglutarate%3B Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bli:BL03930 branched-chain amino acid aminotransferase gene gene4248 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04249 S100027_04250 S100027_04250 S100027_04250 4034882 4036144 + putative MFS-type transporter YvqJ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene4249 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04250 S100027_04251 S100027_04251 S100027_04251 4036246 4037574 - 6-phospho-beta-glucosidase Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Manganese%3B Metal-binding%3B NAD%3B Hydrolyzes phospho-beta-glucosides%3B Belongs to the glycosyl hydrolase 4 family%3B KEGG: bsu:BSU38560 6-phospho-beta-glucosidase gene gene4250 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04251 S100027_04252 S100027_04252 S100027_04252 4037574 4037834 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cytoplasm%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in lichenan transport. Contains 1 PTS EIIA type-3 domain%3B KEGG: cama:F384_22785 PTS system%2C cellobiose-specific IIA component gene gene4251 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04252 S100027_04253 S100027_04253 S100027_04253 4037919 4039271 - Cellobiose permease IIC component Cell membrane%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in cellobiose transport. Contains 1 PTS EIIC type-3 domain gene gene4252 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04253 S100027_04254 S100027_04254 S100027_04254 4039286 4039591 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cytoplasm%3B Kinase%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in cellobiose transport. Contains 1 PTS EIIB type-3 domain%3B KEGG: ebi:EbC_39840 PTS system%2C cellobiose-specific IIB component gene gene4253 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04254 S100027_04255 S100027_04255 S100027_04255 4039718 4041667 - putative licABCH operon regulator Activator%3B Kinase%3B Phosphoprotein%3B Repeat%3B RNA-binding%3B Transcription%3B Transcription regulation%3B Transferase%3B Positive regulator of the licABCH operon. Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains%3B Contains 1 PTS EIIA type-2 domain%3B Contains 1 PTS EIIB type-2 domain gene gene4254 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04255 S100027_04256 S100027_04256 S100027_04256 4041823 4041930 - hypothetical protein gene gene4255 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04256 S100027_04257 S100027_04257 S100027_04257 4041993 4042583 - DNA-3-methyladenine glycosylase II DNA damage%3B DNA repair%3B Hydrolase%3B Belongs to the DNA glycosylase MPG family%3B KEGG: bli:BL05369 DNA-3-methyladenine glycosylase gene gene4256 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04257 S100027_04258 S100027_04258 S100027_04258 4042790 4043461 + putative HTH-type transcriptional regulator in unstable DNA locus DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH gntR-type DNA-binding domain gene gene4257 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04258 S100027_04259 S100027_04259 S100027_04259 4043537 4044652 + Citrate (Si)-synthase Transferase%3B Tricarboxylic acid cycle%3B Belongs to the citrate synthase family%3B KEGG: bli:BL00561 citrate synthase gene gene4258 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04259 S100027_04260 S100027_04260 prpD prpD 4044688 4046127 + 2-methylcitrate dehydratase Lyase%3B Mitochondrion%3B Transit peptide%3B Component of the methylcitrate cycle that catalyzes the dehydration of 2-methylcitrate to 2-methyl-cis-aconitate. The methylcitrate cycle is a metabolic pathway for the consumption of propionic acid%3B Belongs to the PrpD family%3B KEGG: bli:BL00562 2-methylcitrate dehydratase gene gene4259 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04260 S100027_04261 S100027_04261 S100027_04261 4046140 4047057 + Carboxyvinyl-carboxyphosphonate phosphorylmutase Lyase%3B Magnesium%3B Metal-binding%3B Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R%2C3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate%3B Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family%3B KEGG: bli:BL00563 carboxyvinyl-carboxyphosphonate phosphorylmutase gene gene4260 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04261 S100027_04262 S100027_04262 S100027_04262 4047100 4048293 - putative chromate transport protein Cell membrane%3B Chromate resistance%3B Membrane%3B Plasmid%3B Stress response%3B Transmembrane%3B Transmembrane helix%3B Transport%3B May function in the active transport of chromate into the cell under sulfur-deficient conditions. Belongs to the chromate ion transporter (CHR) (TC 2. A. 51) family gene gene4261 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04262 S100027_04263 S100027_04263 S100027_04263 4048306 4048737 - hypothetical protein gene gene4262 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04263 S100027_04264 S100027_04264 S100027_04264 4048760 4050475 - putative ABC transporter ATP-binding protein YwjA ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene4263 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04264 S100027_04265 S100027_04265 S100027_04265 4050590 4051249 - Rhamnogalacturonan acetylesterase RhgT Hydrolase%3B May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls. This enzyme has a broad substrate specificity%2C and shows strong preference for glucose pentaacetate%2C beta-naphthylacetate%2C and p-nitrophenyl acetate (pNPA). Also active toward acetylated xylan%3B Belongs to the 'GDSL' lipolytic enzyme family gene gene4264 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04265 S100027_04266 S100027_04266 S100027_04266 4051562 4052146 + uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix%3B To B. subtilis YuaB gene gene4265 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04266 S100027_04267 S100027_04267 S100027_04267 4052374 4052847 + uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix%3B Required for complex colony architecture gene gene4266 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04267 S100027_04268 S100027_04268 S100027_04268 4052888 4054117 - Multidrug resistance protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Multidrug resistance pump that participates in a low energy shock adaptive response. Belongs to the major facilitator superfamily gene gene4267 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04268 S100027_04269 S100027_04269 S100027_04269 4054227 4055003 - putative transmembrane protein YxlG Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4268 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04269 S100027_04270 S100027_04270 S100027_04270 4055000 4055887 - Putative phosphonates utilization ATP-binding protein ATP-binding%3B Nucleotide-binding%3B Transport%3B Belongs to an operon involved in alkylphosphonate uptake and C-P lyase. Exact function not known. PhnK is not required for the ribophosphonate triphosphate (RPnTP) synthase reaction. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene4269 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04270 S100027_04271 S100027_04271 S100027_04271 4055887 4056099 - Negative regulatory protein YxlE Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Together with YxlD is important for negative regulation of sigma Y activity gene gene4270 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04271 S100027_04272 S100027_04272 S100027_04272 4056096 4056314 - Negative regulatory protein YxlD Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Together with YxlE%2C is important for negative regulation of sigma Y activity%2C being the major negative regulator gene gene4271 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04272 S100027_04273 S100027_04273 S100027_04273 4056315 4056638 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4272 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04273 S100027_04274 S100027_04274 S100027_04274 4056635 4057261 - ECF RNA polymerase sigma factor SigW DNA-binding%3B Sigma factor%3B Stress response%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma factors are held in an inactive form by a cognate anti-sigma factor (RsiW for this protein) until released by regulated membrane proteolysis. Sigma-W controls genes involved in transport processes and detoxification%3B Belongs to the sigma-70 factor family. ECF subfamily gene gene4273 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04274 S100027_04275 S100027_04275 S100027_04275 4057322 4058575 + putative MFS-type transporter YxlH Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily. TCR/Tet family gene gene4274 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04275 S100027_04276 S100027_04276 katE katE 4058619 4060217 - Catalase Cytoplasm%3B Heme%3B Hydrogen peroxide%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Peroxidase%3B Decomposes hydrogen peroxide into water and oxyge%3B serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family%3B KEGG: bli:BL00939 catalase gene gene4275 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04276 S100027_04277 S100027_04277 S100027_04277 4060404 4061861 + Catalase Cytoplasm%3B Heme%3B Hydrogen peroxide%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Peroxidase%3B Decomposes hydrogen peroxide into water and oxyge%3B serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family%3B KEGG: bli:BL00951 catalase gene gene4276 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04277 S100027_04278 S100027_04278 S100027_04278 4061979 4062395 + Peroxide operon regulator Cytoplasm%3B Disulfide bond%3B DNA-binding%3B Manganese%3B Metal-binding%3B Oxidation%3B Repressor%3B Transcription%3B Transcription regulation%3B Zinc%3B Hydrogen and organic peroxide sensor. Represses the expression of a regulon of peroxide-inducible genes such as katA%2C ahpC%2C ahpF%2C the heme biosynthesis operon (hemAXCDBL)%2C fur%2C perR%2C zosA and mrgA. Belongs to the Fur family gene gene4277 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04278 S100027_04279 S100027_04279 S100027_04279 4062402 4063355 + Protoporphyrin ferrochelatase Cytoplasm%3B Heme biosynthesis%3B Iron%3B Lyase%3B Metal-binding%3B Porphyrin biosynthesis%3B Catalyzes the ferrous insertion into protoporphyrin IX%3B Belongs to the ferrochelatase family%3B KEGG: bsu:BSU10130 ferrochelatase gene gene4278 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04279 S100027_04280 S100027_04280 S100027_04280 4063382 4064323 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4279 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04280 S100027_04281 S100027_04281 S100027_04281 4064329 4065231 - Ribose import ATP-binding protein RbsA ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Repeat%3B Sugar transport%3B Transport%3B Part of the ABC transporter complex RbsABCD involved in ribose import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Ribose importer (TC 3. A. 1. 2. 1) family%3B Contains 2 ABC transporter domains gene gene4280 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04281 S100027_04282 S100027_04282 S100027_04282 4065212 4065961 - hypothetical protein gene gene4281 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04282 S100027_04283 S100027_04283 S100027_04283 4065915 4066628 - hypothetical protein gene gene4282 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04283 S100027_04284 S100027_04284 S100027_04284 4066615 4067250 - Sulfate/thiosulfate import ATP-binding protein CysA ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Sulfate transport%3B Transport%3B Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3. A. 1. 6) family%3B Contains 1 ABC transporter domain gene gene4283 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04284 S100027_04285 S100027_04285 S100027_04285 4067253 4067540 - hypothetical protein gene gene4284 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04285 S100027_04286 S100027_04286 S100027_04286 4067540 4067779 - putative HTH-type transcriptional regulator DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene4285 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04286 S100027_04287 S100027_04287 S100027_04287 4067928 4068116 - hypothetical protein gene gene4286 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04287 S100027_04288 S100027_04288 S100027_04288 4068122 4069453 - hypothetical protein gene gene4287 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04288 S100027_04289 S100027_04289 S100027_04289 4069450 4071543 - Lacticin-481/lactococcin-DR transport/processing ATP-binding protein lcnDR3 ATP-binding%3B Bacteriocin transport%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Protease%3B Protein transport%3B Thiol protease%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably implicated in the export process of the lantibiotic lacticin-481/lactococcin-DR. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain%3B Contains 1 peptidase C39 domain gene gene4288 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04289 S100027_04290 S100027_04290 S100027_04290 4071615 4074725 - Lacticin 481/lactococcin biosynthesis protein lcnDR2 Antibiotic biosynthesis%3B Bacteriocin biosynthesis. gene gene4289 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04290 S100027_04291 S100027_04291 S100027_04291 4074776 4074994 - Lantibiotic lichenicidin VK21 A2 Antibiotic%3B Antimicrobial%3B Bacteriocin%3B Lantibiotic%3B Secreted%3B Thioether bond%3B Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes%2C initiated by the formation of aqueous transmembrane pores. When present individually%2C LchA2 exhibits activity towards B. subtilis L1 (IC(50)%3D30 uM)%2C Rhodococcus sp. SS2 (IC(50)%3D16. 6 uM)%2C M. luteus B1314 (IC(50)%3D2. 6 uM)%2C B. megaterium VKM41 (IC(50)%3D2 uM)%2C S. aureus 209p (IC(50)%3D20 uM)%2C B. pumilus 2001%2C B. globigii I%2C B. amyloliquefaciens I%2C M. smegmatis 1171 and M. phlei 1291. However%2C when combined with LchA1%2C it displays much stronger activty against B. subtilis L1 (IC(50)%3D0. 64 uM)%2C Rhodococcus sp. SS2 (IC(50)%3D0. 64 uM)%2C M. luteus B1314 (IC(50)%3D0. 09 uM)%2C B. megaterium VKM41 (IC(50)%3D0. 12 uM) and S. aureus 209p (IC(50)%3D0. 64 uM). The activity of the combined LchA1 and LchA2 peptides is strongest at a molar ratio of 1. Even when applied at 17-fold concentration of the highest IC(50) values for Gram-positive bacteria%2C neither the individual nor the combined peptides display activity against Gram-negative bacteria P. aeruginosa PAO1%2C P. putida I-97 or E. coli C600 gene gene4290 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04291 S100027_04292 S100027_04292 S100027_04292 4075132 4075356 + Lantibiotic lichenicidin Antibiotic%3B Antimicrobial%3B Bacteriocin%3B Cell wall%3B Lantibiotic%3B Secreted%3B Thioether bond%3B Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes%2C initiated by the formation of aqueous transmembrane pores. When present individually%2C LchA1 exhibits activity towards L. lactis HP. When combined with LchA2%2C it displays activity towards a broad spectrum of non-pathogenic and pathogenic Gram-positive bacteria including strains of L. monocytogenes%2C methicillin-resistant S. aureus%2C S. pneumoniae and strains of vancomycin-resistant enterococci%2C but not towards E. faecium L4001 and BM4147-1. Combined LchA1 and LchA2 peptides also inhibit Bacillus sp. HIL-Y85/54728%2C L. lactis DPC3417 and B. halodurans C-125%2C which produce lantibiotics themselves. Inactivated by proteinase K and pronase E%2C but not by trypsin and chymotrypsin gene gene4291 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04292 S100027_04293 S100027_04293 S100027_04293 4075418 4078576 + Lacticin 481/lactococcin biosynthesis protein lcnDR2 Antibiotic biosynthesis%3B Bacteriocin biosynthesis. gene gene4292 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04293 S100027_04294 S100027_04294 S100027_04294 4078867 4079892 + Pectate lyase Calcium%3B Carbohydrate metabolism%3B Cell wall biogenesis/degradation%3B Lyase%3B Metal-binding%3B Polysaccharide degradation%3B Repeat%3B Secreted%3B Signal%3B Cleaves unsaturated oligo-galacturonides from pectin. The major product is trigalacturonat%3B digalacturonate and tetragalacturonate are also produced. Activity on methylated pectins decreases with an increasing degree of methylation (By similarity)%3B Belongs to the polysaccharide lyase 1 family%3B Contains 4 PbH1 repeats%3B KEGG: blh:BaLi_c41260 pectate lyase gene gene4293 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04294 S100027_04295 S100027_04295 S100027_04295 4079929 4080780 - ADP-dependent NAD(P)H-hydrate dehydratase ATP-binding%3B Isomerase%3B Lyase%3B Metal-binding%3B Multifunctional enzyme%3B NAD%3B NADP%3B Nucleotide-binding%3B Potassium%3B Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP%2C which is converted to AMP. This allows the repair of both epimers of NAD(P)HX%2C a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)%3B In the N-terminal sectio%3B belongs to the NnrE/AIBP family%3B In the C-terminal sectio%3B belongs to the NnrD/CARKD family%3B Contains 1 YjeF C-terminal domain%3B Contains 1 YjeF N-terminal domain%3B KEGG: bli:BL00927 ADP-dependent NAD(P)H-hydrate dehydratase gene gene4294 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04295 S100027_04296 S100027_04296 S100027_04296 4080949 4082697 - ATP-binding/permease protein CydD ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system (By similarity)%3B Belongs to the ABC transporter superfamily. Cysteine exporter (TC 3. A. 1. 129. 1) family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene4295 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04296 S100027_04297 S100027_04297 S100027_04297 4082694 4084418 - ATP-binding/permease protein CydC ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system (By similarity)%3B Belongs to the ABC transporter superfamily. Cysteine exporter (TC 3. A. 1. 129. 1) family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene4296 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04297 S100027_04298 S100027_04298 S100027_04298 4084418 4085434 - Cytochrome bd ubiquinol oxidase subunit Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the cytochrome ubiquinol oxidase subunit 2 family%3B KEGG: bli:BL00924 cytochrome d ubiquinol oxidase subunit II%3B With oxygen as acceptor%3B overlaps another CDS with the same product name gene gene4297 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04298 S100027_04299 S100027_04299 S100027_04299 4085421 4086827 - Cytochrome bd ubiquinol oxidase subunit Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the cytochrome ubiquinol oxidase subunit 1 family%3B KEGG: gbm:Gbem_2016 cytochrome d ubiquinol oxidase subunit I%3B With oxygen as acceptor%3B overlaps another CDS with the same product name gene gene4298 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04299 S100027_04300 S100027_04300 S100027_04300 4087626 4088414 + putative transporter YwcJ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the FNT transporter (TC 2. A. 44) family gene gene4299 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04300 S100027_04301 S100027_04301 S100027_04301 4088559 4088888 + hypothetical protein gene gene4300 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04301 S100027_04302 S100027_04302 S100027_04302 4088906 4090237 - Malate dehydrogenase (oxaloacetate-decarboxylating) Metal-binding%3B NAD%3B Oxidoreductase%3B Belongs to the malic enzymes family%3B Contains 1 ACT domain%3B KEGG: bli:BL00922 malate dehydrogenase (oxaloacetate-decarboxylating) gene gene4301 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04302 S100027_04303 S100027_04303 S100027_04303 4090272 4091669 - Malate-2H(+)/Na(+)-lactate antiporter Antiport%3B Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Couples proton uptake and Na(+) efflux to the substrate- product malate/lactate antiport%2C in an electroneutral malate- 2H(+)/Na(+)-lactate exchange. Plays a role in supporting growth to high density on malate at reduced protonmotive force. Belongs to the NhaC Na(+)/H(+) (TC 2. A. 35) antiporter family gene gene4302 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04303 S100027_04304 S100027_04304 S100027_04304 4091912 4093339 - Aspartate ammonia-lyase Lyase%3B Belongs to the class-II fumarase/aspartase family. Aspartase subfamily%3B KEGG: bli:BL05376 aspartate ammonia-lyase gene gene4303 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04304 S100027_04305 S100027_04305 S100027_04305 4093360 4094349 - Asparaginase Alternative initiation%3B Cytoplasm%3B Hydrolase%3B Belongs to the asparaginase 1 family%3B Contains 1 asparaginase/glutaminase domain%3B KEGG: bsu:BSU23580 L-asparaginase gene gene4304 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04305 S100027_04306 S100027_04306 S100027_04306 4094565 4094912 + HTH-type transcriptional regulator AnsR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcriptional repressor for the ans operon coding for L-asparaginase and L-aspartase. NH4(+) may influence this repression. Contains 1 HTH cro/C1-type DNA-binding domain gene gene4305 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04306 S100027_04307 S100027_04307 S100027_04307 4094993 4096039 - 6-phosphogluconolactonase Carbohydrate metabolism%3B Glucose metabolism%3B Hydrolase%3B Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate%3B Belongs to the cycloisomerase 2 family%3B KEGG: bli:BL02413 6-phosphogluconolactonase gene gene4306 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04307 S100027_04308 S100027_04308 S100027_04308 4096236 4096925 + Response regulator ArlR Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system ArlS/ArlR%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene4307 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04308 S100027_04309 S100027_04309 yxdK yxdK 4096922 4097902 + Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Probable member of the two-component regulatory system YxdK/YxdJ. May activate YxdJ in response to the antibacterial protein LL-37%3B Contains 1 histidine kinase domain%3B KEGG: bli:BL02955 two-component system%2C OmpR family%2C sensor histidine kinase YxdK gene gene4308 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04309 S100027_04310 S100027_04310 S100027_04310 4098185 4098961 + Methionine import ATP-binding protein MetN Amino-acid transport%3B ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Methionine importer (TC 3. A. 1. 24) family%3B Contains 1 ABC transporter domain gene gene4309 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04310 S100027_04311 S100027_04311 S100027_04311 4098936 4100813 + ABC transporter permease protein YxdM Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex YxdLM which could be involved in peptide resistance. Belongs to the ABC-4 integral membrane protein family gene gene4310 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04311 S100027_04312 S100027_04312 S100027_04312 4100820 4101170 + uncharacterized protein Signal. gene gene4311 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04312 S100027_04313 S100027_04313 S100027_04313 4101286 4101456 + hypothetical protein gene gene4312 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04313 S100027_04314 S100027_04314 S100027_04314 4101772 4102023 + hypothetical protein gene gene4313 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04314 S100027_04315 S100027_04315 pgaB pgaB 4102056 4102895 - Putative polysaccharide deacetylase YxkH Cell membrane%3B Hydrolase%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Belongs to the polysaccharide deacetylase family%3B KEGG: bbe:BBR47_54040 biofilm PGA synthesis lipoprotein PgaB%3B Hydrolases gene gene4314 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04315 S100027_04316 S100027_04316 S100027_04316 4102956 4103852 - HTH-type transcriptional regulatory protein GabR Activator%3B Aminotransferase%3B DNA-binding%3B Pyridoxal phosphate%3B Repressor%3B Transcription%3B Transcription regulation%3B Transferase%3B Activates the transcription of the gabTD operon. Is also a repressor of its own expression%2C both in the presence and absence of GABA. Binds specifically to the DNA region overlapping the -35 region of the gabT promoter and the -10 and +1 regions of the gabR promoter. Principally regulates the utilization of gamma- aminobutyrate%3B In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene4315 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04316 S100027_04317 S100027_04317 bcsA bcsA 4103993 4106251 - Cellulose synthase (UDP-forming) Cell inner membrane%3B Cell membrane%3B Cellulose biosynthesis%3B Glycosyltransferase%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B In the N-terminal sectio%3B belongs to the glycosyltransferase 2 family%3B In the C-terminal sectio%3B belongs to the AcsB/BcsB family%3B Contains 1 PilZ domain%3B KEGG: bpu:BPUM_3398 cellulose synthase (UDP-forming) gene gene4316 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04317 S100027_04318 S100027_04318 S100027_04318 4106383 4106715 + hypothetical protein gene gene4317 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04318 S100027_04319 S100027_04319 S100027_04319 4106685 4107545 + putative transposase-like protein DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene4318 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04319 S100027_04320 S100027_04320 S100027_04320 4108128 4109480 + Citrate/malate transporter Cell membrane%3B Citrate utilization%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Proton motive force-driven secondary transporter that catalyzes the uptake of both citrate and malate. Appears to be an electroneutral proton-solute symporte%3B the number of protons transported is equal to the valence of the transported anions. Is strictly stereoselective%2C translocating only the (S)-enantiomer of malate. Belongs to the sodium:citrate (SCF) symporter family gene gene4319 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04320 S100027_04321 S100027_04321 S100027_04321 4109527 4110387 - Glycerophosphodiester phosphodiesterase Calcium%3B Glycerol metabolism%3B Hydrolase%3B Metal-binding%3B Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to sn-glycerol 3-phosphate (G3P) and the corresponding alcohols%3B Belongs to the glycerophosphoryl diester phosphodiesterase family%3B Contains 1 GP-PDE domain%3B KEGG: bli:BL02963 glycerophosphoryl diester phosphodiesterase gene gene4320 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04321 S100027_04322 S100027_04322 S100027_04322 4110528 4110797 - uncharacterized protein Signal. gene gene4321 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04322 S100027_04323 S100027_04323 S100027_04323 4110939 4111598 - hypothetical protein gene gene4322 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04323 S100027_04324 S100027_04324 S100027_04324 4111718 4113637 - Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase Cell membrane%3B Cell wall biogenesis/degradation%3B Manganese%3B Membrane%3B Metal-binding%3B Secreted%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate%2C a reaction that presumably uses phosphatidylglycerol (PG) as substrate%3B Belongs to the LTA synthase family%3B KEGG: bli:BL02415 lipoteichoic acid synthase gene gene4323 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04324 S100027_04325 S100027_04325 S100027_04325 4113909 4114466 - uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix%3B To B. subtilis YfjD gene gene4324 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04325 S100027_04326 S100027_04326 S100027_04326 4114639 4115559 - UPF0750 membrane protein YxkD Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0750 family gene gene4325 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04326 S100027_04327 S100027_04327 S100027_04327 4115837 4116277 + Arginine regulator Arginine metabolism%3B Cytoplasm%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Regulates the transcription of the arc operon%2C involved in arginine catabolism%3B Belongs to the ArgR family gene gene4326 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04327 S100027_04328 S100027_04328 arcA arcA 4116545 4117780 + Arginine deiminase Arginine metabolism%3B Cytoplasm%3B Hydrolase%3B Belongs to the arginine deiminase family%3B KEGG: bli:BL01912 arginine deiminase gene gene4327 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04328 S100027_04329 S100027_04329 S100027_04329 4117809 4118816 + Ornithine carbamoyltransferase Arginine metabolism%3B Cytoplasm%3B Transferase%3B Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline%3B Belongs to the ATCase/OTCase family%3B KEGG: bli:BL01914 ornithine carbamoyltransferase gene gene4328 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04329 S100027_04330 S100027_04330 S100027_04330 4118870 4120276 + Putative amino-acid transporter Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Could be an amino acid transporter. Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene4329 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04330 S100027_04331 S100027_04331 S100027_04331 4120298 4121248 + Carbamate kinase Arginine metabolism%3B ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the carbamate kinase family%3B KEGG: bli:BL01916 carbamate kinase gene gene4330 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04331 S100027_04332 S100027_04332 S100027_04332 4121358 4122035 + CRP-like cAMP-activated global transcriptional regulator Activator%3B cAMP%3B cAMP-binding%3B DNA-binding%3B Kinase%3B Nucleotide-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Transferase%3B Global transcriptional regulator that complexes with cAMP and binds to specific DNA promoter sites%2C causing DNA- bending%2C to regulate transcription. cAMP improves binding to specific DNA sequences%2C probably by altering protein conformation. Involved in the regulation of gntP and gntK genes%2C which are involved in gluconate metabolism (PubMed:16385030). May form dimers which bind to the aceB promoter region in the presence of cAMP and repress the glyoxylate bypass genes (PubMed:15150232). It could be a positive regulator of rpf2 gene expression during growth on acetate as the sole carbon source%2C however because the cytosolic cAMP level is elevated in the presence of glucose and low upon growth on acetate%2C it is conceivable that it is unable to function as an activator under acetate conditions (PubMed:18355281)%3B Contains 1 cyclic nucleotide-binding domain%3B Contains 1 HTH crp-type DNA-binding domain gene gene4331 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04332 S100027_04333 S100027_04333 bglB bglB 4122087 4123523 - Beta-glucosidase Chloroplast%3B Disulfide bond%3B Glycosidase%3B Hydrolase%3B Plant defense%3B Plastid%3B Transit peptide%3B Beta-glucosidase acting as a preformed defense system. Hydrolyzes the bisdesmosides avenacosides A and B to 26-desgluco- avenacosides exhibiting fungicidal activity. Can use beta-fucoside > beta-glucoside > beta-galactoside > beta-xyloside as substrates%2C but not alpha-glycosides%2C beta-thioglucosides and disaccharides%3B Belongs to the glycosyl hydrolase 1 family%3B KEGG: bli:BL01920 beta-glucosidase gene gene4332 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04333 S100027_04334 S100027_04334 S100027_04334 4123547 4124866 - Oligo-beta-mannoside permease IIC component Cell membrane%3B Membrane%3B Phosphotransferase system%3B Polysaccharide transport%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in the transport of oligo- glucomannans such as cellobiose or mannobiose (Probable)%3B Contains 1 PTS EIIC type-3 domain gene gene4333 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04334 S100027_04335 S100027_04335 S100027_04335 4125024 4126415 - hypothetical protein gene gene4334 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04335 S100027_04336 S100027_04336 S100027_04336 4126385 4126933 - RNA polymerase sigma factor SigV Activator%3B DNA-binding%3B Sigma factor%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin%2C paraquat and tellurite%3B Belongs to the sigma-70 factor family. ECF subfamily gene gene4335 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04336 S100027_04337 S100027_04337 S100027_04337 4127043 4127672 - [Formate-C-acetyltransferase]-activating enzyme 4Fe-4S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase%3B S-adenosyl-L-methionine%3B Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical%2C using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. Belongs to the organic radical-activating enzymes family%3B KEGG: cbo:CBO1002 anaerobic ribonucleoside-triphosphate reductase activating protein gene gene4336 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04337 S100027_04338 S100027_04338 S100027_04338 4127672 4128337 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4337 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04338 S100027_04339 S100027_04339 S100027_04339 4128330 4128548 - hypothetical protein gene gene4338 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04339 S100027_04340 S100027_04340 S100027_04340 4128560 4129003 - hypothetical protein gene gene4339 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04340 S100027_04341 S100027_04341 S100027_04341 4129020 4130684 - Vesicle-fusing ATPase ATP-binding%3B Chloroplast%3B Nucleotide-binding%3B Plastid%3B Belongs to the AAA ATPase family. Highly divergent%3B KEGG: pca:Pcar_0681 vesicle-fusing ATPase gene gene4340 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04341 S100027_04342 S100027_04342 pepT pepT 4130824 4132056 + Tripeptide aminopeptidase Aminopeptidase%3B Cytoplasm%3B Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Zinc%3B Cleaves the N-terminal amino acid of tripeptides%3B Belongs to the peptidase M20B family%3B KEGG: smaf:D781_1854 tripeptide aminopeptidase gene gene4341 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04342 S100027_04343 S100027_04343 S100027_04343 4132215 4133693 - Beta-fructofuranosidase Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Secreted%3B Signal%3B Exo-fructosidase that can hydrolyze both levan and inulin%2C leading to the production of free fructose. Is also able to hydrolyze sucrose and to a small extent raffinose%2C but not melezitose%2C stachylose%2C cellobiose%2C maltose%2C and lactose%3B Belongs to the glycosyl hydrolase 32 family%3B KEGG: bli:BL01929 beta-fructofuranosidase gene gene4342 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04343 S100027_04344 S100027_04344 S100027_04344 4133708 4134943 - Sucrose transport protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Sugar transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Proton symport transport system. Has an essential role in sucrose metabolism. Belongs to the LacY/RafB permease family gene gene4343 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04344 S100027_04345 S100027_04345 S100027_04345 4135382 4136356 + Catabolite control protein DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcriptional regulator involved in catabolite repression of several operons. Contains 1 HTH lacI-type DNA-binding domain gene gene4344 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04345 S100027_04346 S100027_04346 S100027_04346 4136545 4137069 + hypothetical protein gene gene4345 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04346 S100027_04347 S100027_04347 S100027_04347 4137168 4137851 - uncharacterized protein Signal. gene gene4346 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04347 S100027_04348 S100027_04348 S100027_04348 4137878 4138039 - hypothetical protein gene gene4347 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04348 S100027_04349 S100027_04349 S100027_04349 4138354 4139484 + 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase To B. subtilis YxjH%3B KEGG: tmn:UCRPA7_3279 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase gene gene4348 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04349 S100027_04350 S100027_04350 S100027_04350 4139623 4141857 + Putative mannosyltransferase YkcB Cell membrane%3B Glycosyltransferase%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Belongs to the glycosyltransferase 39 family gene gene4349 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04350 S100027_04351 S100027_04351 S100027_04351 4141857 4142855 + Dolichyl-phosphate beta-D-mannosyltransferase Cell membrane%3B Glycosyltransferase%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Belongs to the glycosyltransferase 2 family. GtrB subfamily%3B KEGG: bld:BLi04189 dolichol-phosphate mannosyltransferase gene gene4350 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04351 S100027_04352 S100027_04352 S100027_04352 4142880 4143875 + UDP-glucose 4-epimerase Carbohydrate metabolism%3B Galactose metabolism%3B Isomerase%3B NAD%3B Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD (By similarity)%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: sbg:SBG_1909 UDP-glucose 4-epimerase gene gene4351 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04352 S100027_04353 S100027_04353 S100027_04353 4144080 4145219 - hypothetical protein gene gene4352 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04353 S100027_04354 S100027_04354 S100027_04354 4145230 4146660 - hypothetical protein gene gene4353 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04354 S100027_04355 S100027_04355 S100027_04355 4146679 4147317 - hypothetical protein gene gene4354 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04355 S100027_04356 S100027_04356 S100027_04356 4147320 4147616 - hypothetical protein gene gene4355 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04356 S100027_04357 S100027_04357 S100027_04357 4148374 4149567 + Pyrimidine nucleoside transport protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the concentrative nucleoside transporter (CNT) (TC 2. A. 41) family gene gene4356 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04357 S100027_04358 S100027_04358 S100027_04358 4149613 4151073 - Catalase Cell wall%3B Glycoprotein%3B Heme%3B Hydrogen peroxide%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Peroxidase%3B Secreted%3B Thioether bond%3B Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide%3B Belongs to the catalase family%3B KEGG: sml:Smlt3583 catalase gene gene4357 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04358 S100027_04359 S100027_04359 S100027_04359 4151077 4151694 - Catalase Heme%3B Hydrogen peroxide%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Peroxidase%3B Sporulation%3B Decomposes hydrogen peroxide into water and oxyge%3B serves to protect cells from the toxic effects of hydrogen peroxide. Involved in sporulation. Belongs to the catalase family. HPII subfamily%3B KEGG: blh:BaLi_c41890 catalase gene gene4358 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04359 S100027_04360 S100027_04360 S100027_04360 4151829 4152305 - hypothetical protein gene gene4359 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04360 S100027_04361 S100027_04361 S100027_04361 4152449 4153867 - 6-phospho-beta-glucosidase Carbohydrate metabolism%3B Cellulose degradation%3B Glycosidase%3B Hydrolase%3B Polysaccharide degradation%3B BglA is intracellular and cleaves cellobiose probably through inorganic phosphate mediated hydrolysis. Belongs to the glycosyl hydrolase 1 family%3B KEGG: bli:BL01946 6-phospho-beta-glucosidase gene gene4360 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04361 S100027_04362 S100027_04362 S100027_04362 4153857 4155716 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Kinase%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in beta-glucoside transport (By similarity)%3B Contains 1 PTS EIIA type-1 domain%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bli:BL01947 PTS system%2C beta-glucosides-specific IIA component gene gene4361 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04362 S100027_04363 S100027_04363 S100027_04363 4156027 4156860 - Beta-glucoside operon antiterminator Activator%3B Phosphoprotein%3B Repeat%3B RNA-binding%3B Transcription%3B Transcription regulation%3B Mediates the positive regulation of the beta-glucoside (arb) operon by functioning as a transcriptional antiterminator. This is an RNA-binding protein that recognizes a specific sequence located just upstream of two termination sites within the operon (By similarity)%3B Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains gene gene4362 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04363 S100027_04364 S100027_04364 S100027_04364 4157055 4157789 - Putative HMP/thiamine permease protein YkoC Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Probably responsible for the translocation of the substrate across the membrane (Probable)%3B Belongs to the CbiQ family gene gene4363 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04364 S100027_04365 S100027_04365 S100027_04365 4157786 4159378 - Putative ABC transporter ATP-binding protein ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Repeat%3B Transport%3B Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 2 ABC transporter domains%3B KEGG: bli:BL02650 energy-coupling factor transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene4364 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04365 S100027_04366 S100027_04366 S100027_04366 4159353 4159952 - Putative HMP/thiamine permease protein YkoE Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Probably responsible for the translocation of the substrate across the membrane (Probable) gene gene4365 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04366 S100027_04367 S100027_04367 S100027_04367 4159949 4160635 - Aminopyrimidine aminohydrolase Hydrolase%3B Thiamine biosynthesis%3B Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds%2C a reaction that is part of a thiamine salvage pathway. Thus%2C catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP). Is also able to catalyze the hydrolytic cleavage of thiamin%3B however%2C this thiaminase activity may not be physiologically relevant. Therefore%2C is probably involved in the regeneration of the thiamine pyrimidine from thiamine degraded products present in the environment%2C rather than in thiamine degradation%3B Belongs to the TenA family%3B KEGG: bli:BL02647 thiaminase (transcriptional activator TenA) gene gene4366 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04367 S100027_04368 S100027_04368 S100027_04368 4161054 4161212 + hypothetical protein gene gene4367 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04368 S100027_04369 S100027_04369 aceA aceA 4161264 4162535 - Isocitrate lyase Glyoxylate bypass%3B Lyase%3B Magnesium%3B Metal-binding%3B Tricarboxylic acid cycle%3B Involved in the persistence and virulence of Mycobacterium. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate%2C a key step of the glyoxylate cycle%2C which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates%3B Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family%3B KEGG: bli:BL02646 isocitrate lyase gene gene4368 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04369 S100027_04370 S100027_04370 aceB aceB 4162550 4164139 - Malate synthase Glyoxylate bypass%3B Glyoxysome%3B Peroxisome%3B Transferase%3B Tricarboxylic acid cycle%3B Belongs to the malate synthase family%3B KEGG: bli:BL02644 malate synthase gene gene4369 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04370 S100027_04371 S100027_04371 S100027_04371 4164182 4164319 - hypothetical protein gene gene4370 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04371 S100027_04372 S100027_04372 arnT arnT 4164524 4166605 + Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase Cell membrane%3B Glycosyltransferase%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Belongs to the glycosyltransferase 39 family%3B KEGG: amo:Anamo_1886 4-amino-4-deoxy-L-arabinose transferase gene gene4371 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04372 S100027_04373 S100027_04373 S100027_04373 4166758 4168698 - Bacitracin export permease protein BceB Antibiotic resistance%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex BceAB (TC 3. A. 1. 123. 5) involved in bacitracin export. Belongs to the ABC-4 integral membrane protein family gene gene4372 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04373 S100027_04374 S100027_04374 S100027_04374 4168688 4169449 - Bacitracin export ATP-binding protein BceA Antibiotic resistance%3B ATP-binding%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex BceAB (TC 3. A. 1. 123. 5) involved in bacitracin export. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: hpo:HMPREF4655_20610 ATP-binding cassette%2C subfamily B%2C bacterial MsbA%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene4373 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04374 S100027_04375 S100027_04375 bceS bceS 4169550 4170554 - Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system BceS/BceR involved in the regulation of bacitracin resistance. Activates BceR in response to extracellular bacitracin%3B Contains 1 histidine kinase domain%3B KEGG: bss:BSUW23_14730 two-component system%2C OmpR family%2C bacitracin resistance sensor histidine kinase BceS gene gene4374 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04375 S100027_04376 S100027_04376 S100027_04376 4170560 4171246 - Sensory transduction protein BceR Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system BceS/BceR involved in the regulation of bacitracin resistance. When activated by BceS%2C binds to the upstream region of the bceAB promoter and up-regulates the expression of these two genes (By similarity)%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene4375 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04376 S100027_04377 S100027_04377 S100027_04377 4171357 4172766 - 6-phospho-beta-glucosidase Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P)%2C phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. BglA and BglH are the major proteins contributing to hydrolysis of MUG-P by extracts of late-exponential-phase or stationary-phase B. subtilis cells%3B Belongs to the glycosyl hydrolase 1 family%3B KEGG: bli:BL00212 6-phospho-beta-glucosidase gene gene4376 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04377 S100027_04378 S100027_04378 S100027_04378 4172807 4174651 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Kinase%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in beta-glucoside transport (By similarity)%3B Contains 1 PTS EIIA type-1 domain%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bsu:BSU39270 PTS system%2C beta-glucosides-specific IIA component gene gene4377 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04378 S100027_04379 S100027_04379 S100027_04379 4174980 4175522 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4378 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04379 S100027_04380 S100027_04380 S100027_04380 4175541 4176530 - Choloylglycine hydrolase Hydrolase%3B Belongs to the peptidase C59 family%3B KEGG: bli:BL00216 choloylglycine hydrolase gene gene4379 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04380 S100027_04381 S100027_04381 S100027_04381 4176658 4177491 - hypothetical protein gene gene4380 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04381 S100027_04382 S100027_04382 S100027_04382 4177513 4178499 - hypothetical protein gene gene4381 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04382 S100027_04383 S100027_04383 S100027_04383 4178714 4179829 - Arabinan endo-1%2C5-alpha-L-arabinosidase Calcium%3B Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Metal-binding%3B Secreted%3B Signal%3B Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the internal cleavage of alpha-(1->5)-L-arabinofuranosyl residues of the alpha-1%2C5-L-arabinan to produce arabino- oligosaccharides and L-arabinose. It is also active toward linear branched sugar beet arabinan%2C and pectin from apple%3B Belongs to the glycosyl hydrolase 43 family%3B KEGG: sde:Sde_2809 arabinan endo-1%2C5-alpha-L-arabinosidase gene gene4382 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04383 S100027_04384 S100027_04384 S100027_04384 4179839 4180441 - hypothetical protein gene gene4383 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04384 S100027_04385 S100027_04385 S100027_04385 4180460 4181239 - hypothetical protein gene gene4384 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04385 S100027_04386 S100027_04386 S100027_04386 4181254 4182846 - Ribonuclease YxiD Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene4385 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04386 S100027_04387 S100027_04387 S100027_04387 4182864 4183133 - hypothetical protein gene gene4386 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04387 S100027_04388 S100027_04388 S100027_04388 4183143 4183535 - hypothetical protein gene gene4387 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04388 S100027_04389 S100027_04389 S100027_04389 4183864 4185165 - Pyrimidine-nucleoside phosphorylase Glycosyltransferase%3B Transferase%3B The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources%2C or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family%3B KEGG: bli:BL00227 pyrimidine-nucleoside phosphorylase gene gene4388 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04389 S100027_04390 S100027_04390 S100027_04390 4185196 4186377 - Pyrimidine nucleoside transport protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the concentrative nucleoside transporter (CNT) (TC 2. A. 41) family gene gene4389 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04390 S100027_04391 S100027_04391 S100027_04391 4186459 4187130 - Deoxyribose-phosphate aldolase Cytoplasm%3B Lyase%3B Schiff base%3B Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate%3B Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily%3B KEGG: bsu:BSU39420 deoxyribose-phosphate aldolase gene gene4390 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04391 S100027_04392 S100027_04392 S100027_04392 4187256 4188194 - Deoxyribonucleoside regulator DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Negative regulator of the dra-nupC-pdp operon. DeoR binds cooperatively to the operator DNA%2C which consists of a palindrome and a direct repeat sequence located 3' to the palindrome. Belongs to the SorC transcriptional regulatory family gene gene4391 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04392 S100027_04393 S100027_04393 S100027_04393 4188230 4188664 - hypothetical protein gene gene4392 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04393 S100027_04394 S100027_04394 S100027_04394 4188781 4189395 + Putative lipoprotein YdaJ Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal. gene gene4393 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04394 S100027_04395 S100027_04395 S100027_04395 4189406 4190227 + Diguanylate cyclase Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Contains 1 GGDEF domain%3B KEGG: bli:BL05221 diguanylate cyclase gene gene4394 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04395 S100027_04396 S100027_04396 S100027_04396 4190217 4191212 + uncharacterized protein Cell membrane%3B Membrane%3B Signal%3B Transmembrane%3B Transmembrane helix. gene gene4395 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04396 S100027_04397 S100027_04397 S100027_04397 4191232 4191939 + uncharacterized protein Cell membrane%3B Membrane%3B Signal%3B Transmembrane%3B Transmembrane helix. gene gene4396 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04397 S100027_04398 S100027_04398 mgdA mgdA 4191932 4193194 + 1%2C2-diacylglycerol 3-glucosyltransferase Glycosyltransferase%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Belongs to the glycosyltransferase 2 family%3B KEGG: synp:Syn7502_03368 1%2C2-diacylglycerol 3-beta-glucosyltransferase gene gene4397 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04398 S100027_04399 S100027_04399 S100027_04399 4193191 4195326 + uncharacterized protein Cell membrane%3B Membrane%3B Signal%3B Transmembrane%3B Transmembrane helix. gene gene4398 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04399 S100027_04400 S100027_04400 avtA avtA 4195357 4196613 - Valine--pyruvate transaminase Aminotransferase%3B Cytoplasm%3B Pyridoxal phosphate%3B Transferase%3B Involved in the biosynthesis of alanine%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bli:BL00232 valine--pyruvate aminotransferase gene gene4399 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04400 S100027_04401 S100027_04401 S100027_04401 4196606 4197880 - hypothetical protein gene gene4400 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04401 S100027_04402 S100027_04402 S100027_04402 4197877 4198443 - hypothetical protein gene gene4401 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04402 S100027_04403 S100027_04403 S100027_04403 4198445 4199722 - Carnosine synthase Amino-acid biosynthesis%3B Arginine biosynthesis%3B Cytoplasm%3B Lyase%3B Plasmid%3B In the C-terminal sectio%3B belongs to the lyase 1 family. Argininosuccinate lyase subfamily%3B Contains 1 ATP-grasp domain%3B KEGG: cme:CYME_CMF080C carnosine synthase gene gene4402 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04403 S100027_04404 S100027_04404 S100027_04404 4199679 4200617 - putative transporter Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene4403 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04404 S100027_04405 S100027_04405 S100027_04405 4200828 4201706 - Fructose-bisphosphate aldolase Lyase%3B Metal-binding%3B Phosphoprotein%3B Zinc%3B Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)%3B Belongs to the class II fructose-bisphosphate aldolase family. IolJ subfamily%3B KEGG: bge:BC1002_3213 fructose-bisphosphate aldolase%2C class II gene gene4404 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04405 S100027_04406 S100027_04406 iolI iolI 4201728 4202564 - 2-keto-myo-inositol isomerase Isomerase%3B Metal-binding%3B Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI%2C inosose or 2%2C4%2C6/3%2C5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2%2C3%2C5/4%2C6- pentahydroxycyclohexanone)%3B Belongs to the IolI family%3B KEGG: bsu:BSU39680 2-keto-myo-inositol isomerase gene gene4405 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04406 S100027_04407 S100027_04407 S100027_04407 4202634 4203500 - Protein IolH gene gene4406 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04407 S100027_04408 S100027_04408 S100027_04408 4203524 4204558 - Inositol 2-dehydrogenase NAD%3B Oxidoreductase%3B Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose)%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: eta:ETA_32880 myo-inositol 2-dehydrogenase / D-chiro-inositol 1-dehydrogenase gene gene4407 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04408 S100027_04409 S100027_04409 S100027_04409 4204583 4205887 - Minor myo-inositol transporter IolF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Minor myo-inositol uptake transporter%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene4408 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04409 S100027_04410 S100027_04410 iolE iolE 4205900 4206802 - Myo-inosose-2 dehydratase Cobalt%3B Lyase%3B Manganese%3B Catalyzes the dehydration of inosose (2-keto-myo- inositol%2C 2KMI or 2%2C4%2C6/3%2C5-pentahydroxycyclohexanone) to 3D- (3%2C5/4)-trihydroxycyclohexane-1%2C2-dione (D-2%2C3-diketo-4-deoxy-epi- inositol)%3B Belongs to the IolE/MocC family%3B KEGG: bli:BL00242 inosose dehydratase gene gene4409 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04410 S100027_04411 S100027_04411 iolD iolD 4206816 4208729 - 3D-(3%2C5/4)-trihydroxycyclohexane-1%2C2-dione acylhydrolase (decyclizing) Hydrolase%3B Magnesium%3B Metal-binding%3B NAD%3B Thiamine pyrophosphate%3B Involved in the cleavage of the C1-C2 bond of 3D- (3%2C5/4)-trihydroxycyclohexane-1%2C2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)%3B Belongs to the TPP enzyme family%3B KEGG: bsu:BSU39730 3D-(3%2C5/4)-trihydroxycyclohexane-1%2C2-dione acylhydrolase (decyclizing) gene gene4410 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04411 S100027_04412 S100027_04412 iolC iolC 4208761 4209738 - 5-dehydro-2-deoxygluconokinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)%3B Belongs to the carbohydrate kinase PfkB family%3B KEGG: bsu:BSU39740 5-dehydro-2-deoxygluconokinase gene gene4411 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04412 S100027_04413 S100027_04413 iolB iolB 4209766 4210581 - 5-deoxy-glucuronate isomerase Isomerase%3B Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)%3B Belongs to the isomerase IolB family%3B KEGG: bli:BL00245 5-deoxy-glucuronate isomerase gene gene4412 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04413 S100027_04414 S100027_04414 doeC doeC 4210656 4212119 - Methylmalonate semialdehyde dehydrogenase (acylating) NAD%3B Oxidoreductase%3B Converts malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA%2C respectively%3B Belongs to the aldehyde dehydrogenase family. IolA subfamily%3B KEGG: vej:VEJY3_17211 aspartate-semialdehyde dehydrogenase%3B With NAD(+) or NADP(+) as acceptor gene gene4413 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04414 S100027_04415 S100027_04415 S100027_04415 4212590 4213354 + HTH-type transcriptional regulator IolR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Iol operon repressor. Contains 1 HTH deoR-type DNA-binding domain gene gene4414 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04415 S100027_04416 S100027_04416 iolS iolS 4213438 4214373 + Protein IolS NADP%3B Oxidoreductase%3B Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily%3B KEGG: bli:BL00183 myo-inositol catabolism protein IolS%3B With NAD(+) or NADP(+) as acceptor gene gene4415 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04416 S100027_04417 S100027_04417 S100027_04417 4214629 4215522 + Glycerophosphodiester phosphodiesterase Calcium%3B Glycerol metabolism%3B Hydrolase%3B Metal-binding%3B Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols. Belongs to the glycerophosphoryl diester phosphodiesterase family%3B Contains 1 GP-PDE domain%3B KEGG: bli:BL00184 glycerophosphoryl diester phosphodiesterase gene gene4416 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04417 S100027_04418 S100027_04418 S100027_04418 4215545 4216903 + Glycerol-3-phosphate transporter Cell membrane%3B Glycerol metabolism%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Responsible for glycerol-3-phosphate uptake. Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2. A. 1. 4) family gene gene4417 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04418 S100027_04419 S100027_04419 S100027_04419 4216956 4218836 - Chaperone protein HtpG ATP-binding%3B Chaperone%3B Cytoplasm%3B Nucleotide-binding%3B Stress response%3B Molecular chaperone. Has ATPase activity%3B Belongs to the heat shock protein 90 family gene gene4418 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04419 S100027_04420 S100027_04420 S100027_04420 4219263 4220798 + Putative phosphonates utilization ATP-binding protein ATP-binding%3B Nucleotide-binding%3B Transport%3B Belongs to an operon involved in alkylphosphonate uptake and C-P lyase. Exact function not known. PhnK is not required for the ribophosphonate triphosphate (RPnTP) synthase reaction. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene4419 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04420 S100027_04421 S100027_04421 S100027_04421 4220834 4221646 - Putative phosphatase Hydrolase%3B Magnesium%3B Metal-binding%3B Belongs to the HAD-like hydrolase superfamily. Cof family gene gene4420 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04421 S100027_04422 S100027_04422 S100027_04422 4221803 4222345 - sn-glycerol-1-phosphate dehydrogenase Cytoplasm%3B Lipid biosynthesis%3B Lipid metabolism%3B Metal-binding%3B NAD%3B NADP%3B Oxidoreductase%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Zinc%3B Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea%3B Belongs to the glycerol-1-phosphate dehydrogenase family%3B KEGG: bli:BL00250 glycerol-1-phosphate dehydrogenase (NAD(P)+) gene gene4421 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04422 S100027_04423 S100027_04423 S100027_04423 4222408 4222851 - sn-glycerol-1-phosphate dehydrogenase Cytoplasm%3B Lipid biosynthesis%3B Lipid metabolism%3B Metal-binding%3B NAD%3B NADP%3B Nickel%3B Oxidoreductase%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species%3B Belongs to the glycerol-1-phosphate dehydrogenase family%3B KEGG: bli:BL00250 glycerol-1-phosphate dehydrogenase (NAD(P)+) gene gene4422 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04423 S100027_04424 S100027_04424 S100027_04424 4222851 4223501 - hypothetical protein gene gene4423 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04424 S100027_04425 S100027_04425 S100027_04425 4223648 4224109 - hypothetical protein gene gene4424 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04425 S100027_04426 S100027_04426 S100027_04426 4224283 4225242 + Iron(3+)-hydroxamate-binding protein YxeB Cell membrane%3B Ion transport%3B Iron%3B Iron transport%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B Part of the ABC transporter complex FhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Partially required for the transport of desferrioxamine%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene4425 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04426 S100027_04427 S100027_04427 S100027_04427 4225267 4225668 - hypothetical protein gene gene4426 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04427 S100027_04428 S100027_04428 S100027_04428 4225874 4226242 + Catechol 2%2C3-dioxygenase KEGG: bpf:BpOF4_17485 catechol 2%2C3-dioxygenase gene gene4427 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04428 S100027_04429 S100027_04429 S100027_04429 4226438 4228450 - Ferrous iron transport protein B like protein Cell inner membrane%3B Cell membrane%3B GTP-binding%3B Manganese%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Not involved in Fe(2+) uptake but is involved in manganese uptake. Could be GTP-driven%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. FeoB GTPase (TC 9. A. 8) family%3B Contains 1 FeoB-type G (guanine nucleotide-binding) domain gene gene4428 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04429 S100027_04430 S100027_04430 S100027_04430 4228447 4228674 - hypothetical protein gene gene4429 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04430 S100027_04431 S100027_04431 S100027_04431 4228858 4229946 - Putative membrane-bound acyltransferase YfiQ Acyltransferase%3B Cell membrane%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Belongs to the acyltransferase 3 family gene gene4430 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04431 S100027_04432 S100027_04432 S100027_04432 4230094 4231980 - ABC transporter permease protein YxdM Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex YxdLM which could be involved in peptide resistance. Belongs to the ABC-4 integral membrane protein family gene gene4431 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04432 S100027_04433 S100027_04433 lolD lolD 4231955 4232719 - ATP-binding cassette sub-family A member Alternative splicing%3B ATP-binding%3B Disease mutation%3B Membrane%3B Nucleotide-binding%3B Polymorphism%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Plays an important role in the formation of pulmonary surfactant%2C probably by transporting lipids such as cholesterol. Belongs to the ABC transporter superfamily. ABCA family%3B Contains 2 ABC transporter domains%3B KEGG: cse:Cseg_2118 lipoprotein-releasing system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene4432 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04433 S100027_04434 S100027_04434 S100027_04434 4232811 4233818 - Sensor histidine kinase YxdK ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Probable member of the two-component regulatory system YxdK/YxdJ. May activate YxdJ in response to the antibacterial protein LL-37%3B Contains 1 histidine kinase domain%3B KEGG: ctc:CTC_p22 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene4433 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04434 S100027_04435 S100027_04435 S100027_04435 4233815 4234522 - Response regulator ArlR Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system ArlS/ArlR%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene4434 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04435 S100027_04436 S100027_04436 S100027_04436 4234705 4235076 + hypothetical protein gene gene4435 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04436 S100027_04437 S100027_04437 S100027_04437 4235105 4236790 - Putative methyl-accepting chemotaxis protein YoaH Cell membrane%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene4436 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04437 S100027_04438 S100027_04438 S100027_04438 4236917 4238341 - putative transporter YflA Cell membrane%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the sodium:alanine (SAF) symporter family gene gene4437 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04438 S100027_04439 S100027_04439 S100027_04439 4238655 4239785 + NAD(P)(+) transhydrogenase (Re/Si-specific) NAD%3B Oxidoreductase%3B May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer%3B Belongs to the AlaDH/PNT family%3B KEGG: eco:b1603 NAD(P) transhydrogenase subunit alpha gene gene4438 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04439 S100027_04440 S100027_04440 S100027_04440 4239945 4241219 - Arabinogalactan endo-beta-1%2C4-galactanase Calcium%3B Glycosidase%3B Hydrolase%3B Metal-binding%3B Signal%3B Hydrolyzes the beta-1%2C4-galactan linkages of arabinogalactan type I%2C a pectic substance found in plants such as soybeans. Belongs to the glycosyl hydrolase 53 family%3B KEGG: bli:BL00263 arabinogalactan endo-1%2C4-beta-galactosidase gene gene4439 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04440 S100027_04441 S100027_04441 S100027_04441 4241324 4243378 - Beta-galactosidase Glycosidase%3B Hydrolase%3B Metal-binding%3B Zinc%3B Hydrolyzes oligosaccharides released by the endo-1%2C4- beta-galactosidase GalA from arabinogalactan type I%2C a pectic plant polysaccharide. It is unable to use lactose as a sole carbon source (By similarity). Catalyzes the hydrolysis of lactose to its constituent monosaccharides glucose and galactose. Possesses a low level of transgalactosylation activity for the production of galacto-oligosaccharides (GOS) from lactose%3B Belongs to the glycosyl hydrolase 42 family%3B KEGG: bli:BL00264 beta-galactosidase gene gene4440 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04441 S100027_04442 S100027_04442 S100027_04442 4243415 4244254 - Putative arabinogalactan oligomer transport system permease protein GanQ Cell membrane%3B Membrane%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Could be part of a binding-protein-dependent transport system for arabinogalactan oligomer%3B probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene4441 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04442 S100027_04443 S100027_04443 S100027_04443 4244258 4245514 - Putative arabinogalactan oligomer transport system permease protein GanP Cell membrane%3B Membrane%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Could be part of a binding-protein-dependent transport system for arabinogalactan oligomer%3B probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene4442 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04443 S100027_04444 S100027_04444 S100027_04444 4245597 4246865 - Cyclodextrin-binding protein Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Sugar transport%3B Transport%3B Binding protein for cyclodextri%3B involved in its cellular uptake. Interacts with all natural cyclodextrins: alpha%2C beta and gamma%3B Belongs to the bacterial solute-binding protein 1 family gene gene4443 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04444 S100027_04445 S100027_04445 S100027_04445 4247010 4248002 - HTH-type transcriptional regulator EbgR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Repressor for beta galactosidase alpha and beta subunits (ebgA and ebgC). Binds lactose as an inducer. Contains 1 HTH lacI-type DNA-binding domain gene gene4444 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04445 S100027_04446 S100027_04446 galK galK 4248258 4249427 + Galactokinase ATP-binding%3B Carbohydrate metabolism%3B Cytoplasm%3B Galactose metabolism%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Transferase%3B Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)%3B Belongs to the GHMP kinase family. GalK subfamily%3B KEGG: bli:BL00191 galactokinase gene gene4445 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04446 S100027_04447 S100027_04447 S100027_04447 4249442 4250443 + UDP-glucose 4-epimerase Carbohydrate metabolism%3B Galactose metabolism%3B Isomerase%3B NAD%3B Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD (By similarity)%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: eal:EAKF1_ch3984 UDP-glucose 4-epimerase gene gene4446 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04447 S100027_04448 S100027_04448 galT galT 4250440 4251927 + UDP-glucose--hexose-1-phosphate uridylyltransferase Carbohydrate metabolism%3B Cytoplasm%3B Galactose metabolism%3B Nucleotidyltransferase%3B Transferase%3B Belongs to the galactose-1-phosphate uridylyltransferase type 2 family%3B KEGG: bli:BL00193 UDPglucose--hexose-1-phosphate uridylyltransferase gene gene4447 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04448 S100027_04449 S100027_04449 S100027_04449 4251964 4253136 - Glucokinase Carbohydrate metabolism%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Xylose metabolism%3B Transcriptional repressor of xylose-utilizing enzymes. Belongs to the ROK (NagC/XylR) family%3B KEGG: tex:Teth514_1432 glucokinase gene gene4448 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04449 S100027_04450 S100027_04450 S100027_04450 4253451 4254182 + Gluconate operon transcriptional repressor DNA-binding%3B Gluconate utilization%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcriptional repressor of the gluconate operon (gntRKPZ)%2C which encodes the proteins for gluconate utilization. Represses mRNA synthesis by binding to the gnt operato%3B the binding is suppressed by gluconate or glucono-delta-lactone. Contains 1 HTH gntR-type DNA-binding domain gene gene4449 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04450 S100027_04451 S100027_04451 gntK gntK 4254175 4255716 + Gluconokinase ATP-binding%3B Gluconate utilization%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the FGGY kinase family%3B KEGG: bsu:BSU40060 gluconokinase gene gene4450 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04451 S100027_04452 S100027_04452 S100027_04452 4255739 4257085 + Gluconate permease Cell membrane%3B Gluconate utilization%3B Membrane%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the GntP permease family gene gene4451 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04452 S100027_04453 S100027_04453 S100027_04453 4257115 4258518 + Phosphogluconate dehydrogenase (NADP(+)-dependent%2C decarboxylating) Gluconate utilization%3B NAD%3B Oxidoreductase%3B Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2)%2C with concomitant reduction of NAD to NADH. Does not contribute to oxidative pentose phosphate (PP) pathway fluxes during growth on glucose. The functional role of GntZ remains obscure%3B Belongs to the 6-phosphogluconate dehydrogenase family%3B KEGG: bsu:BSU40080 6-phosphogluconate dehydrogenase gene gene4452 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04453 S100027_04454 S100027_04454 S100027_04454 4258792 4261395 + Acetaldehyde dehydrogenase (acetylating) NADP%3B Oxidoreductase%3B KEGG: bli:BL00199 acetaldehyde dehydrogenase / alcohol dehydrogenase gene gene4453 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04454 S100027_04455 S100027_04455 S100027_04455 4261860 4262423 + Peroxiredoxin Antioxidant%3B Disulfide bond%3B Oxidoreductase%3B Peroxidase%3B Redox-active center%3B Stress response%3B Directly reduces organic hydroperoxides in its reduced dithiol form. Belongs to the AhpC/TSA family%3B Contains 1 thioredoxin domain%3B KEGG: ssan:NX02_24280 peroxiredoxin (alkyl hydroperoxide reductase subunit C) gene gene4454 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04455 S100027_04456 S100027_04456 ahpF ahpF 4262437 4263966 + NADH dehydrogenase Cell membrane%3B Disulfide bond%3B Electron transport%3B FAD%3B Flavoprotein%3B Membrane%3B NAD%3B Oxidoreductase%3B Redox-active center%3B Transport%3B Ubiquinone%3B Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)%3B Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: meh:M301_0244 alkyl hydroperoxide reductase subunit F%3B With a disulfide as acceptor gene gene4455 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04456 S100027_04457 S100027_04457 S100027_04457 4264536 4265165 - hypothetical protein gene gene4456 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04457 S100027_04458 S100027_04458 S100027_04458 4265233 4266249 - hypothetical protein gene gene4457 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04458 S100027_04459 S100027_04459 S100027_04459 4266434 4268077 + uncharacterized protein Cytoplasm%3B Nucleus. gene gene4458 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04459 S100027_04460 S100027_04460 S100027_04460 4268068 4268385 + dCTP diphosphatase KEGG: cit:102607840 dCTP diphosphatase gene gene4459 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04460 S100027_04461 S100027_04461 S100027_04461 4268667 4269563 + Nucleotide-binding protein ExpZ ATP-binding%3B Nucleotide-binding%3B Repeat%3B Belongs to the ABC transporter superfamily%3B Contains 2 ABC transporter domains gene gene4460 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04461 S100027_04462 S100027_04462 S100027_04462 4269565 4270113 + Putative transport permease YvfS Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the ABC-2 integral membrane protein family%3B Contains 1 ABC transmembrane type-2 domain gene gene4461 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04462 S100027_04463 S100027_04463 S100027_04463 4270304 4271311 + Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system YvfT/YvfU. Probably activates YvfU by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: blh:BaLi_c43020 two-component system%2C NarL family%2C sensor histidine kinase DesK%3B overlaps another CDS with the same product name gene gene4462 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04463 S100027_04464 S100027_04464 S100027_04464 4271283 4271444 + Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system YvfT/YvfU. Probably activates YvfU by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bld:BLi04303 two-component system%2C NarL family%2C sensor histidine kinase DesK%3B overlaps another CDS with the same product name gene gene4463 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04464 S100027_04465 S100027_04465 S100027_04465 4271441 4272034 + putative transcriptional regulatory protein YvfU Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system YvfT/YvfU%3B Contains 1 HTH luxR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene4464 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04465 S100027_04466 S100027_04466 S100027_04466 4272682 4274655 - hypothetical protein gene gene4465 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04466 S100027_04467 S100027_04467 S100027_04467 4275002 4275358 - hypothetical protein gene gene4466 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04467 S100027_04468 S100027_04468 S100027_04468 4275355 4276050 - Manganese transport system ATP-binding protein MntB ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Transport%3B This protein is probably a component of a manganese permease%2C a binding protein-dependent%2C ATP-driven transport system. Probably responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene4467 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04468 S100027_04469 S100027_04469 S100027_04469 4277013 4277393 - hypothetical protein gene gene4468 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04469 S100027_04470 S100027_04470 S100027_04470 4278176 4278334 + hypothetical protein gene gene4469 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04470 S100027_04471 S100027_04471 rlmH rlmH 4279062 4279541 - 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase Cytoplasm%3B Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA%3B Belongs to the RNA methyltransferase RlmH family%3B KEGG: bli:BL02382 23S rRNA (pseudouridine1915-N3)-methyltransferase gene gene4470 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04471 S100027_04472 S100027_04472 S100027_04472 4279622 4279780 - uncharacterized protein gene gene4471 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04472 S100027_04473 S100027_04473 S100027_04473 4279979 4280518 - hypothetical protein gene gene4472 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04473 S100027_04474 S100027_04474 S100027_04474 4280892 4281413 - Phosphinothricin acetyltransferase Acyltransferase%3B Transferase%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: gwc:GWCH70_2852 phosphinothricin acetyltransferase gene gene4473 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04474 S100027_04475 S100027_04475 S100027_04475 4281441 4281911 - hypothetical protein gene gene4474 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04475 S100027_04476 S100027_04476 S100027_04476 4282168 4283013 - Adenosyl-chloride synthase Chloride%3B S-adenosyl-L-methionine%3B Transferase%3B Involved in the biosynthesis of the proteosome inhibitor salinosporamide A (SalA). Catalyzes the halogenation of S- adenosyl-L-methionine (SAM) with chloride to generate 5'-chloro- 5'-deoxyadenosine (5'-CIDA) and L-methionine. It can also use bromide and iodide%2C producing halogenated 5'-deoxyadenosine (5'- XDA) and L-methionine%2C however no halogenase activity is detected in the presence of fluoride%3B Belongs to the SalL family gene gene4475 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04476 S100027_04477 S100027_04477 S100027_04477 4283310 4284521 - Peptidase Do Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Serine protease%3B Transmembrane%3B Transmembrane helix%3B Belongs to the peptidase S1C family%3B Contains 1 PDZ (DHR) domain%3B KEGG: afl:Aflv_2834 serine protease Do gene gene4476 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04477 S100027_04478 S100027_04478 S100027_04478 4284604 4285398 - Putative metallo-hydrolase YycJ Hydrolase%3B Metal-binding%3B Belongs to the metallo-beta-lactamase superfamily%3B KEGG: rch:RUM_07740 ribonuclease J%3B Acting on ester bonds gene gene4477 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04478 S100027_04479 S100027_04479 S100027_04479 4285413 4286261 - Two-component system YycFG regulatory protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Together with YycH%2C regulates the activity of the two- component system YycF/YycG gene gene4478 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04479 S100027_04480 S100027_04480 S100027_04480 4286248 4287612 - Two-component system YycF/YycG regulatory protein YycH Calcium%3B Cell membrane%3B Membrane%3B Metal-binding%3B Transmembrane%3B Transmembrane helix%3B Together with YycI%2C regulates the activity of the two- component system YycF/YycG gene gene4479 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04480 S100027_04481 S100027_04481 vicK vicK 4287602 4289446 - Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon%2C the yocH and ykvT%2C cwlO%2C lytE%2C ydjM%2C yjeA%2C yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B Contains 1 PAC (PAS-associated C-terminal) domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bli:BL02372 two-component system%2C OmpR family%2C sensor histidine kinase VicK gene gene4480 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04481 S100027_04482 S100027_04482 S100027_04482 4289454 4290161 - Phosphate regulon transcriptional regulatory protein Activator%3B Cytoplasm%3B DNA-binding%3B Phosphate transport%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Transport%3B Two-component regulatory system%3B This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited (By similarity)%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene4481 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04482 S100027_04483 S100027_04483 S100027_04483 4290580 4290652 - tRNA-Phe tRNA gene4482 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04483 S100027_04484 S100027_04484 S100027_04484 4290679 4290755 - tRNA-Asp tRNA gene4483 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04484 S100027_04485 S100027_04485 S100027_04485 4290844 4290915 - tRNA-Glu tRNA gene4484 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04485 S100027_04486 S100027_04486 S100027_04486 4290923 4290998 - tRNA-Lys tRNA gene4485 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04486 S100027_04487 S100027_04487 S100027_04487 4291214 4291627 - 8-oxo-dGTP diphosphatase Hydrolase%3B Magnesium%3B Manganese%3B Metal-binding%3B Probably mediates the hydrolysis of some nucleoside diphosphate derivatives%3B Belongs to the Nudix hydrolase family%3B Contains 1 nudix hydrolase domain%3B KEGG: blh:BaLi_c43220 8-oxo-dGTP diphosphatase gene gene4486 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04487 S100027_04488 S100027_04488 purA purA 4291691 4292983 - Adenylosuccinate synthase Cytoplasm%3B GTP-binding%3B Ligase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Purine biosynthesis%3B Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP%3B Belongs to the adenylosuccinate synthetase family%3B KEGG: vvu:VV2_0768 adenylosuccinate synthase gene gene4487 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04488 S100027_04489 S100027_04489 S100027_04489 4293248 4293514 + hypothetical protein gene gene4488 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04489 S100027_04490 S100027_04490 S100027_04490 4293532 4294896 - DNA helicase ATP-binding%3B DNA replication%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Primosome%3B Belongs to the helicase family. DnaB subfamily%3B Contains 1 SF4 helicase domain%3B KEGG: bsu:BSU40440 replicative DNA helicase gene gene4489 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04490 S100027_04491 S100027_04491 S100027_04491 4295090 4295287 + uncharacterized protein gene gene4490 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04491 S100027_04492 S100027_04492 S100027_04492 4295325 4295543 - hypothetical protein gene gene4491 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04492 S100027_04493 S100027_04493 S100027_04493 4295686 4295823 + uncharacterized protein gene gene4492 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04493 S100027_04494 S100027_04494 S100027_04494 4295894 4297099 + 2-nitroimidazole transporter Antibiotic resistance%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in efflux of 2-nitroimidazole%3B Belongs to the major facilitator superfamily. Cyanate porter (TC 2. A. 1. 17) family gene gene4493 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04494 S100027_04495 S100027_04495 S100027_04495 4297232 4298482 + N-acetylglucosamine-6-phosphate deacetylase Carbohydrate metabolism%3B Hydrolase%3B Iron%3B Metal-binding%3B Involved in the first committed step in the biosynthesis of amino-sugar-nucleotides. Catalyzes the hydrolysis of the N- acetyl group of N-acetylglucosamine-6-phosphate (GlcNAc-6-P) to yield glucosamine 6-phosphate and acetate%3B Belongs to the NagA family%3B KEGG: bli:BL00084 N-acetylglucosamine-6-phosphate deacetylase gene gene4494 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04495 S100027_04496 S100027_04496 S100027_04496 4298479 4299225 + Glucosamine-6-phosphate deaminase Carbohydrate metabolism%3B Hydrolase%3B Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion%3B Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily%3B KEGG: bli:BL00085 glucosamine-6-phosphate deaminase gene gene4495 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04496 S100027_04497 S100027_04497 S100027_04497 4299222 4299953 + HTH-type transcriptional repressor YvoA DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Acts as a weak repressor of yflG expression%3B Contains 1 HTH gntR-type DNA-binding domain gene gene4496 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04497 S100027_04498 S100027_04498 S100027_04498 4299950 4300846 + N-acetylmuramic acid 6-phosphate etherase Carbohydrate metabolism%3B Lyase%3B Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate%2C producing GlcNAc 6- phosphate and D-lactate%3B Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily%3B Contains 1 SIS domain%3B KEGG: syd:Syncc9605_1393 N-acetylmuramic acid 6-phosphate etherase gene gene4497 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04498 S100027_04499 S100027_04499 S100027_04499 4300849 4302222 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Kinase%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylglucosamine transport (By similarity)%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bli:BL00088 PTS system%2C N-acetylglucosamine-specific IIB component gene gene4498 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04499 S100027_04500 S100027_04500 S100027_04500 4302259 4302708 - 50S ribosomal protein L9 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Binds to the 23S rRNA%3B Belongs to the ribosomal protein L9P family gene gene4499 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04500 S100027_04501 S100027_04501 S100027_04501 4302705 4304687 - uncharacterized protein Contains 1 GGDEF domain gene gene4500 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04501 S100027_04502 S100027_04502 S100027_04502 4304723 4305616 - uncharacterized protein gene gene4501 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04502 S100027_04503 S100027_04503 S100027_04503 4306164 4306640 + Spore coat protein Sporulation%3B Belongs to the CotF family gene gene4502 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04503 S100027_04504 S100027_04504 S100027_04504 4306683 4307102 - TRAP-T-associated universal stress protein TeaD ATP-binding%3B Cytoplasm%3B Nucleotide-binding%3B ATP-binding protein that negatively regulates activity of the tripartite ATP-independent periplasmic (TRAP) ectoine transport system TeaABC. May regulate uptake according to the ATP status of the cell%3B Belongs to the universal stress protein A family gene gene4503 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04504 S100027_04505 S100027_04505 S100027_04505 4307120 4308586 - Bicarbonate transporter BicA Cell inner membrane%3B Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Low/medium affinity%2C Na(+)-dependent bicarbonate transporter%3B Belongs to the SLC26A/SulP transporter (TC 2. A. 53) family%3B Contains 1 STAS domain gene gene4504 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04505 S100027_04506 S100027_04506 S100027_04506 4308802 4310103 + putative transporter YybO Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily. Phthalate permease family gene gene4505 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04506 S100027_04507 S100027_04507 S100027_04507 4310181 4310420 - 30S ribosomal protein S18 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA%2C where it helps stabilize the platform of the 30S subunit%3B Belongs to the ribosomal protein S18P family gene gene4506 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04507 S100027_04508 S100027_04508 S100027_04508 4310472 4310984 - Single-stranded DNA-binding protein DNA damage%3B DNA recombination%3B DNA repair%3B DNA replication%3B DNA-binding%3B Plays an important role in DNA replication%2C recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism%3B Contains 1 SSB domain gene gene4507 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04508 S100027_04509 S100027_04509 S100027_04509 4311031 4311318 - 30S ribosomal protein S6%2C chloroplastic Chloroplast%3B Plastid%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Binds together with S18 to 16S ribosomal RNA%3B Belongs to the ribosomal protein S6P family gene gene4508 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04509 S100027_04510 S100027_04510 S100027_04510 4311432 4312532 - Ribosome-binding ATPase YchF ATP-binding%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner%3B Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily%3B Contains 1 OBG-type G (guanine nucleotide-binding) domain gene gene4509 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04510 S100027_04511 S100027_04511 S100027_04511 4312711 4312920 - uncharacterized protein gene gene4510 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04511 S100027_04512 S100027_04512 S100027_04512 4313005 4314003 - uncharacterized protein gene gene4511 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04512 S100027_04513 S100027_04513 S100027_04513 4314322 4314939 + uncharacterized protein gene gene4512 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04513 S100027_04514 S100027_04514 S100027_04514 4314976 4315824 - Stage 0 sporulation protein J Chromosome partition%3B DNA-binding%3B Sporulation%3B Required for the initiation of sporulation and for normal chromosome segregation. Antagonizes sporulation inhibition by Soj. It probably interacts with a specific DNA site and other proteins involved in partitioning and cell division%2C and antagonizes Soj in response to cell cycle events related to chromosome partitioning%3B Belongs to the ParB family gene gene4513 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04514 S100027_04515 S100027_04515 S100027_04515 4315817 4316578 - Putative septum site-determining protein MinD ATP-binding%3B Cell cycle%3B Cell division%3B Chloroplast%3B Nucleotide-binding%3B Plastid%3B Septation%3B ATPase required for the correct placement of the division site%3B Belongs to the ParA family. MinD subfamily gene gene4514 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04515 S100027_04516 S100027_04516 S100027_04516 4316821 4317264 - uncharacterized protein gene gene4515 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04516 S100027_04517 S100027_04517 S100027_04517 4317331 4318188 - hypothetical protein gene gene4516 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04517 S100027_04518 S100027_04518 S100027_04518 4318244 4319095 - Nucleoid occlusion protein Cell cycle%3B Cell division%3B Cytoplasm%3B DNA-binding%3B Septation%3B Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid%2C especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid%2C which would cause chromosome breakage%3B Belongs to the ParB family gene gene4517 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04518 S100027_04519 S100027_04519 gidB gidB 4319193 4319945 - 16S rRNA (guanine(527)-N(7))-methyltransferase Cytoplasm%3B Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B Specifically methylates the N7 position of guanine in position 535 of 16S rRNA%3B Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family%3B KEGG: bli:BL00108 16S rRNA (guanine527-N7)-methyltransferase gene gene4518 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04519 S100027_04520 S100027_04520 S100027_04520 4319926 4321812 - tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG Cytoplasm%3B FAD%3B Flavoprotein%3B NAD%3B tRNA processing%3B NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs%2C forming tRNA-cmnm(5)s(2)U34%3B Belongs to the MnmG family gene gene4519 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04520 S100027_04521 S100027_04521 mnmE mnmE 4321829 4323208 - tRNA modification GTPase MnmE Cytoplasm%3B GTP-binding%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Potassium%3B tRNA processing%3B Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs%2C forming tRNA- cmnm(5)s(2)U34%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. TrmE GTPase family%3B Contains 1 TrmE-type G (guanine nucleotide-binding) domain%3B KEGG: bsu:BSU41020 tRNA modification GTPase%3B Acting on acid anhydrides gene gene4520 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04521 S100027_04522 S100027_04522 S100027_04522 4323543 4324166 - Protein jag RNA-binding%3B Contains 1 KH domain%3B Contains 1 R3H domain gene gene4521 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04522 S100027_04523 S100027_04523 S100027_04523 4324163 4324960 - Membrane protein insertase MisCA Cell membrane%3B Chaperone%3B Lipoprotein%3B Membrane%3B Palmitate%3B Protein transport%3B Signal%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex%2C as well as at least some lipoproteins (By similarity). Also involved in protein secretion processes. Essential for sporulation by activating sigma factor SpoIIIG/SigG after engulfment is completed in the prespore%2C maybe by acting on SpoIIIAE. It has an overlapping%2C although partly distinct%2C function compared to YqjG(MisCB)%3B Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily gene gene4522 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04523 S100027_04524 S100027_04524 rnpA rnpA 4325130 4325423 - Ribonuclease P Endonuclease%3B Hydrolase%3B Nuclease%3B RNA-binding%3B tRNA processing%3B RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4. 5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme%3B Belongs to the RnpA family%3B KEGG: bsu:BSU41050 ribonuclease P protein component gene gene4523 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04524 S100027_04525 S100027_04525 S100027_04525 23 622 + putative 35.5 kDa protein in gldA 3'region gene gene4524 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04525 S100027_04526 S100027_04526 S100027_04526 666 1139 + tRNA (cytidine(34)-2'-O)-methyltransferase Cytoplasm%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B tRNA processing%3B Could methylate the ribose at the nucleotide 34 wobble position in tRNA%3B Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily%3B KEGG: gpb:HDN1F_07340 tRNA (cytidine/uridine-2'-O-)-methyltransferase gene gene4525 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04526 S100027_04527 S100027_04527 S100027_04527 1231 1845 + uncharacterized protein gene gene4526 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04527 S100027_04528 S100027_04528 S100027_04528 1860 2570 + uncharacterized protein gene gene4527 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04528 S100027_04529 S100027_04529 S100027_04529 2585 3286 + uncharacterized protein gene gene4528 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04529 S100027_04530 S100027_04530 S100027_04530 3687 5582 + Protein PrkA Belongs to the PrkA family gene gene4529 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04530 S100027_04531 S100027_04531 S100027_04531 5757 6443 + Stress response UPF0229 protein YhbH Stress response%3B Belongs to the UPF0229 family gene gene4530 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04531 S100027_04532 S100027_04532 S100027_04532 6664 8256 - hypothetical protein gene gene4531 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04532 S100027_04533 S100027_04533 S100027_04533 8427 8615 - hypothetical protein gene gene4532 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04533 S100027_04534 S100027_04534 S100027_04534 8737 9621 - hypothetical protein gene gene4533 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04534 S100027_04535 S100027_04535 S100027_04535 9635 9775 - hypothetical protein gene gene4534 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04535 S100027_04536 S100027_04536 S100027_04536 10078 10260 - hypothetical protein gene gene4535 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04536 S100027_04537 S100027_04537 S100027_04537 10265 10585 - hypothetical protein gene gene4536 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04537 S100027_04538 S100027_04538 S100027_04538 10678 10824 - hypothetical protein gene gene4537 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04538 S100027_04539 S100027_04539 S100027_04539 11003 11413 + hypothetical protein gene gene4538 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04539 S100027_04540 S100027_04540 S100027_04540 12216 12653 + hypothetical protein gene gene4539 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04540 S100027_04541 S100027_04541 S100027_04541 13343 13444 - hypothetical protein gene gene4540 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04541 S100027_04542 S100027_04542 S100027_04542 13458 13958 - hypothetical protein gene gene4541 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04542 S100027_04543 S100027_04543 S100027_04543 13986 14225 - hypothetical protein gene gene4542 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04543 S100027_04544 S100027_04544 S100027_04544 14237 14740 - hypothetical protein gene gene4543 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04544 S100027_04545 S100027_04545 S100027_04545 14742 15032 - hypothetical protein gene gene4544 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04545 S100027_04546 S100027_04546 S100027_04546 15134 15334 - hypothetical protein gene gene4545 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04546 S100027_04547 S100027_04547 S100027_04547 15412 15774 - hypothetical protein gene gene4546 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04547 S100027_04548 S100027_04548 S100027_04548 15861 16316 - hypothetical protein gene gene4547 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04548 S100027_04549 S100027_04549 S100027_04549 16467 16640 - hypothetical protein gene gene4548 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04549 S100027_04550 S100027_04550 S100027_04550 18064 18411 + hypothetical protein gene gene4549 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04550 S100027_04551 S100027_04551 S100027_04551 18746 19513 + hypothetical protein gene gene4550 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04551 S100027_04552 S100027_04552 S100027_04552 19839 19961 - hypothetical protein gene gene4551 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04552 S100027_04553 S100027_04553 S100027_04553 19951 21072 - Response regulator aspartate phosphatase Hydrolase%3B Protein phosphatase%3B Repeat%3B TPR repeat%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bli:BL02161 response regulator aspartate phosphatase I%3B Acting on ester bonds gene gene4552 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04553 S100027_04554 S100027_04554 S100027_04554 21303 21476 + uncharacterized protein gene gene4553 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04554 S100027_04555 S100027_04555 S100027_04555 21645 23309 + Ribonuclease YxiD Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene4554 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04555 S100027_04556 S100027_04556 S100027_04556 23331 23792 + hypothetical protein gene gene4555 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04556 S100027_04557 S100027_04557 S100027_04557 23845 24309 + hypothetical protein gene gene4556 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04557 S100027_04558 S100027_04558 S100027_04558 24440 25303 + hypothetical protein gene gene4557 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04558 S100027_04559 S100027_04559 S100027_04559 25432 25677 + hypothetical protein gene gene4558 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04559 S100027_04560 S100027_04560 S100027_04560 25955 26194 + Putative uncharacterized protein ORFD in retron EC67 Transposable element%3B To phage P2 uncharacterized 12. 9 kDa protein in gpA 3'region gene gene4559 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04560 S100027_04561 S100027_04561 S100027_04561 26216 26404 + hypothetical protein gene gene4560 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04561 S100027_04562 S100027_04562 S100027_04562 26508 26720 + hypothetical protein gene gene4561 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04562 S100027_04563 S100027_04563 S100027_04563 26717 27037 + hypothetical protein gene gene4562 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04563 S100027_04564 S100027_04564 S100027_04564 27030 27386 + hypothetical protein gene gene4563 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04564 S100027_04565 S100027_04565 S100027_04565 27482 28156 + SPBc2 prophage-derived UPF0714 protein YoqZ Belongs to the UPF0714 family gene gene4564 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04565 S100027_04566 S100027_04566 S100027_04566 28331 30085 + SPBc2 prophage-derived uncharacterized protein YorA Repeat%3B Contains 13 PbH1 repeats gene gene4565 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04566 S100027_04567 S100027_04567 S100027_04567 30508 30735 + hypothetical protein gene gene4566 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04567 S100027_04568 S100027_04568 S100027_04568 30680 30829 + hypothetical protein gene gene4567 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04568 S100027_04569 S100027_04569 S100027_04569 30961 31707 + UPF0736 protein Belongs to the UPF0736 family gene gene4568 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04569 S100027_04570 S100027_04570 S100027_04570 31700 32122 + dCMP deaminase Hydrolase%3B Metal-binding%3B Zinc%3B Dispensable for transformability. Belongs to the cytidine and deoxycytidylate deaminase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: blr:BRLA_c013630 dCMP deaminase gene gene4569 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04570 S100027_04571 S100027_04571 S100027_04571 32106 32375 + Putative transition state regulator Abh DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 SpoVT-AbrB domain%3B To B. subtilis AbrB and SpoVT gene gene4570 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04571 S100027_04572 S100027_04572 S100027_04572 32499 32732 + hypothetical protein gene gene4571 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04572 S100027_04573 S100027_04573 S100027_04573 32735 32932 + hypothetical protein gene gene4572 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04573 S100027_04574 S100027_04574 S100027_04574 33118 33519 + hypothetical protein gene gene4573 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04574 S100027_04575 S100027_04575 S100027_04575 33516 33827 + hypothetical protein gene gene4574 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04575 S100027_04576 S100027_04576 S100027_04576 33927 34709 + hypothetical protein gene gene4575 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04576 S100027_04577 S100027_04577 S100027_04577 34719 35207 + hypothetical protein gene gene4576 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04577 S100027_04578 S100027_04578 S100027_04578 35182 35883 + hypothetical protein gene gene4577 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04578 S100027_04579 S100027_04579 S100027_04579 35897 36394 + hypothetical protein gene gene4578 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04579 S100027_04580 S100027_04580 S100027_04580 36493 37137 + hypothetical protein gene gene4579 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04580 S100027_04581 S100027_04581 S100027_04581 37266 37544 + hypothetical protein gene gene4580 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04581 S100027_04582 S100027_04582 S100027_04582 37544 38101 + hypothetical protein gene gene4581 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04582 S100027_04583 S100027_04583 S100027_04583 38124 38897 + hypothetical protein gene gene4582 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04583 S100027_04584 S100027_04584 S100027_04584 38959 39261 - hypothetical protein gene gene4583 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04584 S100027_04585 S100027_04585 S100027_04585 39740 40417 + hypothetical protein gene gene4584 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04585 S100027_04586 S100027_04586 S100027_04586 40417 42003 + hypothetical protein gene gene4585 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04586 S100027_04587 S100027_04587 S100027_04587 42096 43454 + hypothetical protein gene gene4586 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04587 S100027_04588 S100027_04588 S100027_04588 43471 44520 + hypothetical protein gene gene4587 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04588 S100027_04589 S100027_04589 S100027_04589 44541 44960 + hypothetical protein gene gene4588 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04589 S100027_04590 S100027_04590 S100027_04590 44990 45919 + hypothetical protein gene gene4589 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04590 S100027_04591 S100027_04591 S100027_04591 45992 46390 + hypothetical protein gene gene4590 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04591 S100027_04592 S100027_04592 S100027_04592 46393 46755 + hypothetical protein gene gene4591 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04592 S100027_04593 S100027_04593 S100027_04593 46755 46916 + hypothetical protein gene gene4592 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04593 S100027_04594 S100027_04594 S100027_04594 46932 47438 + hypothetical protein gene gene4593 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04594 S100027_04595 S100027_04595 S100027_04595 47780 48499 + hypothetical protein gene gene4594 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04595 S100027_04596 S100027_04596 S100027_04596 48518 48988 + hypothetical protein gene gene4595 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04596 S100027_04597 S100027_04597 S100027_04597 49251 49703 + hypothetical protein gene gene4596 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04597 S100027_04598 S100027_04598 S100027_04598 49696 50193 + hypothetical protein gene gene4597 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04598 S100027_04599 S100027_04599 S100027_04599 50199 50663 + hypothetical protein gene gene4598 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04599 S100027_04600 S100027_04600 S100027_04600 50676 56636 + putative tape measure protein Antimicrobial%3B Bacteriolytic enzyme%3B Coiled coil%3B Degradation of host cell envelope components during virus entry%3B Degradation of host peptidoglycans during virus entry%3B Lyase%3B Viral genome ejection through host cell envelope%3B Viral penetration into host cytoplasm%3B Viral tail assembly%3B Virion%3B Virus entry into host cell%3B Virus exit from host cell%3B Serves as a base for tail tube protein polymerization and acts as a template for tail length determination. Exolysin involved in host peptidoglycan digestion necessary for viral DNA entry into the host cell (PubMed:14763988)%3B Belongs to the P2likevirus tape measure protein family gene gene4599 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04600 S100027_04601 S100027_04601 S100027_04601 56636 56998 + hypothetical protein gene gene4600 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04601 S100027_04602 S100027_04602 S100027_04602 57015 61124 + hypothetical protein gene gene4601 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04602 S100027_04603 S100027_04603 S100027_04603 61144 63546 + hypothetical protein gene gene4602 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04603 S100027_04604 S100027_04604 S100027_04604 63567 64106 + hypothetical protein gene gene4603 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04604 S100027_04605 S100027_04605 S100027_04605 64128 64592 + hypothetical protein gene gene4604 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04605 S100027_04606 S100027_04606 S100027_04606 64692 64994 + hypothetical protein gene gene4605 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04606 S100027_04607 S100027_04607 S100027_04607 65022 66101 + N-acetylmuramoyl-L-alanine amidase Cell wall biogenesis/degradation%3B Competence%3B Hydrolase%3B Secreted%3B Sporulation%3B Autolysins are involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella and sporulation. Involved in prophage SP-beta-mediated cell lysis%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B KEGG: psab:PSAB_06125 N-acetylmuramoyl-L-alanine amidase gene gene4606 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04607 S100027_04608 S100027_04608 S100027_04608 66114 66398 + hypothetical protein gene gene4607 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04608 S100027_04609 S100027_04609 S100027_04609 66473 66838 + hypothetical protein gene gene4608 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04609 S100027_04610 S100027_04610 S100027_04610 66897 67415 + hypothetical protein gene gene4609 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04610 S100027_04611 S100027_04611 S100027_04611 67426 67977 - hypothetical protein gene gene4610 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04611 S100027_04612 S100027_04612 S100027_04612 67974 68840 - Thymidylate synthase Cytoplasm%3B Methyltransferase%3B Nucleotide biosynthesis%3B Transferase%3B Provides the sole de novo source of dTMP for DNA biosynthesis%3B Belongs to the thymidylate synthase family. Bacterial- type ThyA subfamily%3B KEGG: bsu:BSU17680 thymidylate synthase gene gene4611 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04612 S100027_04613 S100027_04613 S100027_04613 68809 69324 - Dihydrofolate reductase Cell cycle%3B Cell division%3B Chromosome partition%3B Cytoplasm%3B Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)%3B Belongs to the ScpA family%3B Contains 1 DHFR (dihydrofolate reductase) domain%3B KEGG: xfa:XF2331 dihydrofolate reductase gene gene4612 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04613 S100027_04614 S100027_04614 S100027_04614 69335 70066 - hypothetical protein gene gene4613 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04614 S100027_04615 S100027_04615 dnaQ dnaQ 70066 70692 - DNA-directed DNA polymerase KEGG: lgr:LCGT_1296 DNA polymerase III subunit epsilon gene gene4614 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04615 S100027_04616 S100027_04616 S100027_04616 70720 70902 - hypothetical protein gene gene4615 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04616 S100027_04617 S100027_04617 S100027_04617 70918 71928 - hypothetical protein gene gene4616 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04617 S100027_04618 S100027_04618 S100027_04618 71931 72110 - hypothetical protein gene gene4617 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04618 S100027_04619 S100027_04619 S100027_04619 72166 73506 - DNA helicase KEGG: sbw:TGUWTKB_3580 replicative DNA helicase gene gene4618 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04619 S100027_04620 S100027_04620 S100027_04620 73499 74038 - Guanylate kinase KEGG: cbl:CLK_A0185 guanylate kinase gene gene4619 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04620 S100027_04621 S100027_04621 S100027_04621 74068 74760 - hypothetical protein gene gene4620 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04621 S100027_04622 S100027_04622 S100027_04622 74829 75041 - hypothetical protein gene gene4621 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04622 S100027_04623 S100027_04623 S100027_04623 75034 75420 - hypothetical protein gene gene4622 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04623 S100027_04624 S100027_04624 S100027_04624 75493 75777 - hypothetical protein gene gene4623 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04624 S100027_04625 S100027_04625 S100027_04625 75842 76285 - hypothetical protein gene gene4624 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04625 S100027_04626 S100027_04626 S100027_04626 76344 77012 - hypothetical protein ATP-binding%3B Cytoplasm%3B Nucleotide-binding%3B Belongs to the PhoH family gene gene4625 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04626 S100027_04627 S100027_04627 S100027_04627 77043 77588 - hypothetical protein gene gene4626 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04627 S100027_04628 S100027_04628 S100027_04628 77612 78151 - hypothetical protein gene gene4627 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04628 S100027_04629 S100027_04629 S100027_04629 78181 79182 - hypothetical protein gene gene4628 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04629 S100027_04630 S100027_04630 S100027_04630 79172 79429 - hypothetical protein gene gene4629 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04630 S100027_04631 S100027_04631 S100027_04631 79493 80443 - hypothetical protein gene gene4630 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04631 S100027_04632 S100027_04632 S100027_04632 80552 81592 - Ribonucleoside-diphosphate reductase DNA replication%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase small chain family%3B KEGG: bha:BH0502 ribonucleoside-diphosphate reductase beta chain gene gene4631 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04632 S100027_04633 S100027_04633 S100027_04633 81668 83998 - Ribonucleoside-diphosphate reductase Allosteric enzyme%3B ATP-binding%3B Disulfide bond%3B DNA replication%3B Nucleotide-binding%3B Oxidoreductase%3B Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase large chain family%3B Contains 1 ATP-cone domain%3B KEGG: sml:Smlt2842 ribonucleoside-diphosphate reductase alpha chain gene gene4632 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04633 S100027_04634 S100027_04634 S100027_04634 84010 84384 - hypothetical protein gene gene4633 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04634 S100027_04635 S100027_04635 S100027_04635 84377 84625 - hypothetical protein gene gene4634 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04635 S100027_04636 S100027_04636 S100027_04636 84630 84944 - hypothetical protein gene gene4635 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04636 S100027_04637 S100027_04637 S100027_04637 85157 85336 - hypothetical protein gene gene4636 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04637 S100027_04638 S100027_04638 S100027_04638 85425 85901 + UPF0229 protein Belongs to the UPF0229 family gene gene4637 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04638 S100027_04639 S100027_04639 S100027_04639 86209 86841 + Putative efflux system component YhbJ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene4638 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04639 S100027_04640 S100027_04640 S100027_04640 86881 88470 + Lincomycin resistance protein LmrB Antibiotic resistance%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Proton-dependent transporter. May mediate the efflux of lincomycin. Belongs to the major facilitator superfamily. EmrB family gene gene4639 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04640 S100027_04641 S100027_04641 S100027_04641 88488 89018 + NAD(P)H dehydrogenase (quinone) Contains 1 flavodoxin-like domain%3B KEGG: bsl:A7A1_3824 NAD(P)H dehydrogenase (quinone) gene gene4640 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04641 S100027_04642 S100027_04642 S100027_04642 89032 89364 + hypothetical protein gene gene4641 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04642 S100027_04643 S100027_04643 S100027_04643 90145 90354 + hypothetical protein gene gene4642 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04643 S100027_04644 S100027_04644 S100027_04644 90374 91297 + Monosaccharide-transporting ATPase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Phosphonate transport%3B Transport%3B Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3. A. 1. 9. 1) family%3B Contains 1 ABC transporter domain%3B KEGG: yen:YE0142 simple sugar transport system ATP-binding protein gene gene4643 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04644 S100027_04645 S100027_04645 S100027_04645 91290 92231 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4644 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04645 S100027_04646 S100027_04646 S100027_04646 92305 93165 - putative transposase-like protein DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene4645 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04646 S100027_04647 S100027_04647 S100027_04647 93135 93467 - hypothetical protein gene gene4646 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04647 S100027_04648 S100027_04648 S100027_04648 93638 93838 - Cold shock protein CspB Activator%3B Cytoplasm%3B DNA-binding%3B Stress response%3B Transcription%3B Transcription regulation%3B Binds to the pentamer sequences ATTGG and CCAAT with highest affinity in single-stranded DNA%2C and also to other sequences. Has greater affinity for ATTGG than CCAAT. Can act as transcriptional activator of cold shock genes by recognizing putative ATTGG-box elements present in promoter regions of genes induced under cold shock conditions%3B Contains 1 CSD (cold-shock) domain gene gene4647 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04648 S100027_04649 S100027_04649 S100027_04649 94354 95355 + Methionine import ATP-binding protein MetN Amino-acid transport%3B ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Methionine importer (TC 3. A. 1. 24) family%3B Contains 1 ABC transporter domain gene gene4648 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04649 S100027_04650 S100027_04650 S100027_04650 95358 96008 + D-methionine transport system permease protein MetI Amino-acid transport%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system for D-methionine and the toxic methionine analog alpha-methyl- methionine. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene4649 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04650 S100027_04651 S100027_04651 S100027_04651 96030 96848 + D-methionine-binding lipoprotein MetQ Amino-acid transport%3B Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B This protein is a component of a D-methionine permease%2C a binding protein-dependent%2C ATP-driven transport system%3B Belongs to the NlpA lipoprotein family gene gene4650 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04651 S100027_04652 S100027_04652 S100027_04652 97286 97660 + L-cystine uptake protein TcyP Amino-acid transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mediates uptake of L-cystine%2C the oxidized form of L- cysteine%3B Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family%3B overlaps another CDS with the same product name gene gene4651 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04652 S100027_04653 S100027_04653 S100027_04653 97615 98031 + L-cystine uptake protein TcyP Amino-acid transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mediates uptake of L-cystine%2C the oxidized form of L- cysteine%3B Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family%3B overlaps another CDS with the same product name gene gene4652 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04653 S100027_04654 S100027_04654 S100027_04654 98851 99093 - Prolyl oligopeptidase Alternative splicing%3B Aminopeptidase%3B Cell membrane%3B Disulfide bond%3B Glycoprotein%3B Hydrolase%3B Membrane%3B Protease%3B Serine protease%3B Signal-anchor%3B Transmembrane%3B Transmembrane helix%3B Removes N-terminal dipeptides sequentially from polypeptides (By similarity). Essential for control of distal tip cell migration%3B Belongs to the peptidase S9B family. DPPIV subfamily%3B KEGG: cps:CPS_3511 prolyl oligopeptidase%3B overlaps another CDS with the same product name gene gene4653 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04654 S100027_04655 S100027_04655 S100027_04655 99090 99992 - Prolyl oligopeptidase Aminopeptidase%3B Hydrolase%3B Protease%3B Serine protease%3B Signal%3B Exopeptidase that catalyzes the removal of dipeptide units (NH2-P2-P1- or -P1'-P2'-COOH) from the free amino or carboxy termini. Prefers substrates composed of bulky%2C hydrophobic amino acids at P1 and P1' positions. Has endopeptidase activity on N- terminally blocked peptide derivatives which contain aromatic amino acid residue at the P1 position. Exopeptidase activity is much higher than its endopeptidase activity%3B Belongs to the peptidase S9 family%3B KEGG: cps:CPS_3511 prolyl oligopeptidase%3B overlaps another CDS with the same product name gene gene4654 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04655 S100027_04656 S100027_04656 S100027_04656 100111 100461 - hypothetical protein gene gene4655 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04656 S100027_04657 S100027_04657 S100027_04657 100413 100571 - hypothetical protein gene gene4656 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04657 S100027_04658 S100027_04658 S100027_04658 891 1952 + Phage-like element PBSX protein XkdV To B. subtilis YqcC gene gene4657 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04658 S100027_04659 S100027_04659 S100027_04659 2341 2616 + hypothetical protein gene gene4658 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04659 S100027_04660 S100027_04660 S100027_04660 2637 2807 + hypothetical protein gene gene4659 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04660 S100027_04661 S100027_04661 S100027_04661 2834 3097 + hypothetical protein gene gene4660 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04661 S100027_04662 S100027_04662 S100027_04662 3615 4055 + N-acetylmuramoyl-L-alanine amidase Antimicrobial%3B Bacteriolytic enzyme%3B Cell cycle%3B Cell division%3B Cell wall biogenesis/degradation%3B Glycosidase%3B Hydrolase%3B Repeat%3B Secreted%3B Septation%3B Signal%3B Required for cell separation during growth%3B Belongs to the glycosyl hydrolase 73 family%3B Contains 3 LysM repeats%3B KEGG: bli:BL00542 N-acetylmuramoyl-L-alanine amidase gene gene4661 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04662 S100027_04663 S100027_04663 S100027_04663 4118 4444 + hypothetical protein gene gene4662 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04663 S100027_04664 S100027_04664 S100027_04664 4463 4780 + hypothetical protein gene gene4663 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04664 S100027_04665 S100027_04665 S100027_04665 4818 5084 - hypothetical protein gene gene4664 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04665 S100027_04666 S100027_04666 S100027_04666 5105 6619 - Poly(glycerol-phosphate) alpha-glucosyltransferase Cell inner membrane%3B Cell membrane%3B Glycosyltransferase%3B Membrane%3B Transferase%3B Adds a GalNAc residue on to the Und-PP-Bac2%2C4diNAc- GalNAc disaccharide in the N-linked protein glycosylation pathway. Transfers the third sugar in the heptasaccharide biosynthesis%3B Belongs to the glycosyltransferase group 1 family%3B KEGG: bso:BSNT_02005 poly(glycerol-phosphate) alpha-glucosyltransferase gene gene4665 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04666 S100027_04667 S100027_04667 S100027_04667 6683 6898 - hypothetical protein gene gene4666 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04667 S100027_04668 S100027_04668 S100027_04668 7058 7876 + hypothetical protein gene gene4667 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04668 S100027_04669 S100027_04669 S100027_04669 7949 8278 + hypothetical protein gene gene4668 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04669 S100027_04670 S100027_04670 S100027_04670 8754 9713 + Tyrosine recombinase XerC Cell cycle%3B Cell division%3B Chromosome partition%3B Cytoplasm%3B DNA integration%3B DNA recombination%3B DNA-binding%3B Site-specific tyrosine recombinase%2C which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids%3B Belongs to the 'phage' integrase family. XerC subfamily gene gene4669 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04670 S100027_04671 S100027_04671 S100027_04671 9973 10377 + hypothetical protein gene gene4670 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04671 S100027_04672 S100027_04672 S100027_04672 10338 10901 + hypothetical protein gene gene4671 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04672 S100027_04673 S100027_04673 S100027_04673 10918 11292 + hypothetical protein gene gene4672 http://www.ncbi.nlm.nih.gov/gene/?term=S100027_04673