locus_tag old_locus_tag gene Name start end strand product note type ID NCBI S100141_00001 S100141_00001 S100141_00001 336 1124 + putative ABC transporter permease protein YurN Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably part of the binding-protein-dependent transport system YurMNO. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene0 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00001 S100141_00002 S100141_00002 S100141_00002 1128 2012 + putative ABC transporter permease protein YurM Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably part of the binding-protein-dependent transport system YurMNO. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00002 S100141_00003 S100141_00003 frlD frlD 2026 2169 + Fructosamine kinase FrlD ATP-binding%3B Carbohydrate metabolism%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Catalyzes the phosphorylation of a range of fructosamines to fructosamine 6-phosphates%3B Belongs to the carbohydrate kinase PfkB family%3B KEGG: bsr:I33_3361 fructoselysine 6-kinase%3B Phosphotransferases with an alcohol group as acceptor gene gene2 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00003 S100141_00004 S100141_00004 S100141_00004 2189 2878 + Fructosamine kinase FrlD ATP-binding%3B Carbohydrate metabolism%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Catalyzes the phosphorylation of a range of fructosamines to fructosamine 6-phosphates%3B Belongs to the carbohydrate kinase PfkB family%3B KEGG: bss:BSUW23_15905 fructoselysine 6-kinase%3B Phosphotransferases with an alcohol group as acceptor gene gene3 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00004 S100141_00005 S100141_00005 S100141_00005 2903 3631 - putative HTH-type transcriptional regulator YurK DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH gntR-type DNA-binding domain gene gene4 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00005 S100141_00006 S100141_00006 ugpC ugpC 3885 4892 + Glycerol-3-phosphate-transporting ATPase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Sugar transport%3B Transport%3B Part of the binding-protein-dependent transport system for alpha-glucosides such as sucrose%2C maltose and trehalose. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: eco:b3450 sn-glycerol 3-phosphate transport system ATP-binding protein gene gene5 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00006 S100141_00007 S100141_00007 S100141_00007 4942 5811 - Extracellular ribonuclease Hydrolase%3B Nuclease%3B Secreted%3B Signal. gene gene6 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00007 S100141_00008 S100141_00008 allC allC 6011 7252 + Allantoate deiminase Hydrolase%3B Metal-binding%3B Purine metabolism%3B Zinc%3B Involved in the anaerobic utilization of allantoin. Converts allantoate to (S)-ureidoglycolate and ammonia%3B Belongs to the peptidase M20 family%3B KEGG: bao:BAMF_3048 allantoate deiminase gene gene7 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00008 S100141_00009 S100141_00009 pucG pucG 7271 8524 + Purine catabolism protein PucG Aminotransferase%3B Purine metabolism%3B Pyridoxal phosphate%3B Transferase%3B Could encode ureidoglycolase or L-alanine:glyoxylate aminotransferase%2C or perhaps both activities%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bay:RBAM_029580 (S)-ureidoglycine-glyoxylate aminotransferase%3B Transaminases gene gene8 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00009 S100141_00010 S100141_00010 S100141_00010 8646 9842 + Multidrug resistance protein Antibiotic resistance%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Energy-dependent efflux pump responsible for decreased drug accumulation in multi-drug-resistant cells. Probably uses a transmembrane proton gradient as the energy source. Causes the efflux of a variety of toxic substances%2C including such structurally diverse compounds as ethidium bromide%2C rhodamine and acridine dyes%2C tetraphenylphosphonium%2C puromycin%2C chloramphenicol%2C doxorubicin%2C and fluoroquinolone antibiotics. Belongs to the major facilitator superfamily. TCR/Tet family gene gene9 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00010 S100141_00011 S100141_00011 S100141_00011 9875 10069 + hypothetical protein gene gene10 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00011 S100141_00012 S100141_00012 S100141_00012 10186 10512 - uncharacterized protein gene gene11 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00012 S100141_00013 S100141_00013 S100141_00013 10524 11102 - uncharacterized protein gene gene12 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00013 S100141_00014 S100141_00014 S100141_00014 11240 12670 - Purine catabolism regulatory protein Activator%3B DNA-binding%3B Purine metabolism%3B Repressor%3B Transcription%3B Transcription regulation%3B Activates the expression of pucFG%2C pucH%2C pucI%2C pucJKLM and guaD%2C while it represses pucABCDE and its own expression%3B Belongs to the CdaR family%3B overlaps another CDS with the same product name gene gene13 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00014 S100141_00015 S100141_00015 S100141_00015 12667 12834 - Purine catabolism regulatory protein Activator%3B DNA-binding%3B Purine metabolism%3B Repressor%3B Transcription%3B Transcription regulation%3B Activates the expression of pucFG%2C pucH%2C pucI%2C pucJKLM and guaD%2C while it represses pucABCDE and its own expression%3B Belongs to the CdaR family%3B overlaps another CDS with the same product name gene gene14 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00015 S100141_00016 S100141_00016 ura4 ura4 13014 14378 + Dihydroorotase Hydrolase%3B Metal-binding%3B Purine metabolism%3B Zinc%3B Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring%3B Belongs to the DHOase family. Allantoinase subfamily%3B KEGG: xau:Xaut_1415 dihydroorotase gene gene15 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00016 S100141_00017 S100141_00017 S100141_00017 14451 14804 + uncharacterized protein gene gene16 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00017 S100141_00018 S100141_00018 S100141_00018 14831 15682 + UPF0759 protein YunF Belongs to the UPF0759 family gene gene17 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00018 S100141_00019 S100141_00019 S100141_00019 15702 16523 + UPF0721 transmembrane protein YunE Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0721 family gene gene18 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00019 S100141_00020 S100141_00020 S100141_00020 16541 17935 + 5'-nucleotidase Coiled coil%3B Hydrolase%3B Metal-binding%3B Belongs to the metallophosphoesterase superfamily%3B KEGG: llm:llmg_0192 5'-nucleotidase gene gene19 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00020 S100141_00021 S100141_00021 S100141_00021 18062 18820 + Sporulation protein YunB Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Required for sporulation gene gene20 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00021 S100141_00022 S100141_00022 S100141_00022 18858 19835 - L-Ala--D-Glu endopeptidase Cell cycle%3B Cell wall biogenesis/degradation%3B Differentiation%3B Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Signal%3B Sporulation%3B Zinc%3B L-Ala--D-Glu endopeptidase involved in production of single L-alanine side chains from tetrapeptides in the spore cortex peptidoglycan. Therefore%2C is required for the endospore cortex maturation%3B Belongs to the peptidase M23B family gene gene21 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00022 S100141_00023 S100141_00023 lipA lipA 20038 20934 + Lipoyl synthase 4Fe-4S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B S-adenosyl-L-methionine%3B Transferase%3B Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes%2C thereby converting the octanoylated domains into lipoylated derivatives%3B Belongs to the radical SAM superfamily. Lipoyl synthase family%3B KEGG: bsu:BSU32330 lipoic acid synthetase gene gene22 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00023 S100141_00024 S100141_00024 S100141_00024 21152 21427 + uncharacterized protein Disulfide bond. gene gene23 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00024 S100141_00025 S100141_00025 S100141_00025 21453 21887 + UPF0331 protein YutE Belongs to the UPF0331 family gene gene24 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00025 S100141_00026 S100141_00026 S100141_00026 21921 22691 + 4-nitrophenylphosphatase Belongs to the HAD-like hydrolase superfamily. NagD family%3B KEGG: bao:BAMF_3033 4-nitrophenyl phosphatase gene gene25 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00026 S100141_00027 S100141_00027 pgpA pgpA 22718 23218 - Phosphatidylglycerophosphatase To B. subtilis YpjQ%3B KEGG: acl:ACL_0288 phosphatidylglycerophosphatase A gene gene26 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00027 S100141_00028 S100141_00028 S100141_00028 23372 24388 + Endospore coat-associated protein YutH Membrane%3B Sporulation%3B Involved in sporulation%3B Belongs to the CotS family gene gene27 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00028 S100141_00029 S100141_00029 S100141_00029 24590 25891 + Homoserine dehydrogenase Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Isoleucine biosynthesis%3B Methionine biosynthesis%3B NADP%3B Oxidoreductase%3B Threonine biosynthesis%3B Belongs to the homoserine dehydrogenase family%3B Contains 1 ACT domain%3B KEGG: seds:AAY24_06030 homoserine dehydrogenase gene gene28 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00029 S100141_00030 S100141_00030 thrC thrC 25882 26949 + Threonine synthase Amino-acid biosynthesis%3B Lyase%3B Pyridoxal phosphate%3B Threonine biosynthesis%3B Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine%3B Belongs to the threonine synthase family%3B KEGG: bsl:A7A1_2331 threonine synthase gene gene29 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00030 S100141_00031 S100141_00031 S100141_00031 26946 27875 + Homoserine kinase Amino-acid biosynthesis%3B ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Threonine biosynthesis%3B Transferase%3B Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate%3B Belongs to the GHMP kinase family. Homoserine kinase subfamily%3B KEGG: bsu:BSU32240 homoserine kinase gene gene30 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00031 S100141_00032 S100141_00032 apeH apeH 27979 29238 + Acylaminoacyl-peptidase Hydrolase%3B Protease%3B Serine protease%3B Belongs to the peptidase S9B family%3B KEGG: bce:BC0192 acylaminoacyl-peptidase gene gene31 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00032 S100141_00033 S100141_00033 S100141_00033 29304 29585 + Acylaminoacyl-peptidase Hydrolase%3B Protease%3B Serine protease%3B Belongs to the peptidase S9B family%3B KEGG: gka:GK0961 acylaminoacyl-peptidase gene gene32 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00033 S100141_00034 S100141_00034 S100141_00034 29996 30232 - Putative nitrogen fixation protein YutI Nitrogen fixation%3B May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins%3B Belongs to the NifU family gene gene33 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00034 S100141_00035 S100141_00035 S100141_00035 30411 30737 + Putative disulfide oxidoreductase YuzD Disulfide bond%3B Redox-active center. gene gene34 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00035 S100141_00036 S100141_00036 S100141_00036 30775 31842 - NADH dehydrogenase FAD%3B Flavoprotein%3B Oxidoreductase%3B Belongs to the NADH dehydrogenase family%3B KEGG: bsu:BSU32200 NADH dehydrogenase gene gene35 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00036 S100141_00037 S100141_00037 S100141_00037 32109 32345 + UPF0349 protein Belongs to the UPF0349 family gene gene36 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00037 S100141_00038 S100141_00038 S100141_00038 32480 33697 + putative transporter YutK Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the concentrative nucleoside transporter (CNT) (TC 2. A. 41) family gene gene37 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00038 S100141_00039 S100141_00039 dapF dapF 33821 34675 + Diaminopimelate epimerase Amino-acid biosynthesis%3B Cytoplasm%3B Disulfide bond%3B Isomerase%3B Lysine biosynthesis%3B Catalyzes the stereoinversion of LL-2%2C6- diaminoheptanedioate (L%2CL-DAP) to meso-diaminoheptanedioate (meso- DAP)%2C a precursor of L-lysine and an essential component of the bacterial peptidoglycan%3B Belongs to the diaminopimelate epimerase family%3B KEGG: bsu:BSU32170 diaminopimelate epimerase gene gene38 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00039 S100141_00040 S100141_00040 S100141_00040 34752 35114 + Iron-sulfur cluster insertion protein ErpA Iron%3B Iron-sulfur%3B Metal-binding%3B Required for insertion of 4Fe-4S clusters for at least IspG%3B Belongs to the HesB/IscA family gene gene39 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00040 S100141_00041 S100141_00041 dltE dltE 35257 36018 - putative oxidoreductase DltE Cytoplasm%3B NAD%3B Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: enr:H650_10080 uncharacterized oxidoreductase%3B Oxidoreductases gene gene40 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00041 S100141_00042 S100141_00042 rimJ rimJ 36389 36934 + Ribosomal-protein-alanine N-acetyltransferase Acyltransferase%3B Cytoplasm%3B Transferase%3B This enzyme acetylates the N-terminal alanine of ribosomal protein S5%3B Belongs to the acetyltransferase family. RimJ subfamily%3B Contains 1 N-acetyltransferase domain%3B KEGG: bya:BANAU_3114 ribosomal-protein-alanine N-acetyltransferase gene gene41 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00042 S100141_00043 S100141_00043 S100141_00043 37247 37765 + hypothetical protein gene gene42 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00043 S100141_00044 S100141_00044 S100141_00044 37829 38167 + hypothetical protein gene gene43 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00044 S100141_00045 S100141_00045 S100141_00045 38250 39905 + hypothetical protein gene gene44 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00045 S100141_00046 S100141_00046 S100141_00046 39898 40602 + General L-amino acid transport ATP-binding protein AapP Amino-acid transport%3B ATP-binding%3B Nucleotide-binding%3B Transport%3B Part of a binding-protein-dependent transport system for L-amino acids%2C affects the uptake as well as the efflux of these amino acids. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene45 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00046 S100141_00047 S100141_00047 S100141_00047 40602 41126 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B To M. jannaschii MJ0706 and Synechocystis PCC 6803 slr1478 gene gene46 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00047 S100141_00048 S100141_00048 S100141_00048 41143 41364 + hypothetical protein gene gene47 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00048 S100141_00049 S100141_00049 guaC guaC 41427 42407 - GMP reductase NADP%3B Oxidoreductase%3B Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase%2C nucleoside and nucleotide derivatives of G to A nucleotides%2C and in maintaining the intracellular balance of A and G nucleotides%3B Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily%3B KEGG: bsu:BSU32130 GMP reductase gene gene48 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00049 S100141_00050 S100141_00050 S100141_00050 42498 42767 + uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix. gene gene49 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00050 S100141_00051 S100141_00051 trxB trxB 42806 43801 - Thioredoxin-disulfide reductase FAD%3B Flavoprotein%3B NADP%3B Oxidoreductase%3B Belongs to the ferredoxin--NADP reductase type 2 family%3B KEGG: bsu:BSU32110 thioredoxin reductase (NADPH) gene gene50 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00051 S100141_00052 S100141_00052 S100141_00052 44113 44475 + NADH dehydrogenase FAD%3B Flavoprotein%3B Oxidoreductase%3B Belongs to the NADH dehydrogenase family%3B KEGG: bsu:BSU32100 NADH dehydrogenase gene gene51 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00052 S100141_00053 S100141_00053 S100141_00053 44730 45332 + NADH dehydrogenase FAD%3B Flavoprotein%3B Oxidoreductase%3B Belongs to the NADH dehydrogenase family%3B KEGG: bsu:BSU32100 NADH dehydrogenase gene gene52 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00053 S100141_00054 S100141_00054 S100141_00054 45700 46020 + putative membrane protein YuiB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene53 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00054 S100141_00055 S100141_00055 S100141_00055 46121 46762 + uncharacterized protein Signal. gene gene54 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00055 S100141_00056 S100141_00056 S100141_00056 46792 47268 - putative membrane protein YuiD Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene55 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00056 S100141_00057 S100141_00057 carP carP 47416 48906 + Leucyl aminopeptidase Aminopeptidase%3B Cytoplasm%3B Hydrolase%3B Manganese%3B Metal-binding%3B Protease%3B Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides%3B Belongs to the peptidase M17 family%3B KEGG: bao:BAMF_3001 leucyl aminopeptidase gene gene56 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00057 S100141_00058 S100141_00058 S100141_00058 49038 50366 + Putative amino acid transporter YuiF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport. gene gene57 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00058 S100141_00059 S100141_00059 S100141_00059 50412 51005 - Putative biotin transporter BioYB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Putative biotin transporter%3B Belongs to the BioY family gene gene58 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00059 S100141_00060 S100141_00060 yedY yedY 51105 51701 + putative oxidoreductase YuiH Metal-binding%3B Molybdenum%3B Oxidoreductase%3B KEGG: bsu:BSU32020 sulfoxide reductase catalytic subunit YedY%3B Acting on a sulfur group of donors gene gene59 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00060 S100141_00061 S100141_00061 S100141_00061 51877 52746 + Ferri-bacillibactin esterase BesA Cytoplasm%3B Hydrolase%3B Serine esterase%3B Catalyzes the hydrolysis of the trilactone cycle of ferri-bacillibactin (ferri-BB) complex%2C leading to the formation of bacillibactin monomers and to cytosolic iron release%2C thus making iron available for metabolic use. Can also hydrolyze bacillibactin (BB)%2C however the catalytic efficiency for ferri-BB hydrolysis is much higher than for BB%3B Belongs to the esterase D family gene gene60 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00061 S100141_00062 S100141_00062 entA entA 52882 53667 + 2%2C3-dihydro-2%2C3-dihydroxybenzoate dehydrogenase Heterocyst%3B Oxidoreductase%3B May be involved in repressing heterocyst differentiation and may be essential for preventing all vegetative cells from differentiating. Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bss:BSUW23_15560 2%2C3-dihydro-2%2C3-dihydroxybenzoate dehydrogenase gene gene61 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00062 S100141_00063 S100141_00063 entC entC 53691 54887 + Isochorismate synthase Isomerase%3B Phosphoprotein%3B Belongs to the isochorismate synthase family%3B KEGG: bay:RBAM_029040 isochorismate synthase gene gene62 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00063 S100141_00064 S100141_00064 entE entE 54906 56531 + (2%2C3-dihydroxybenzoyl)adenylate synthase ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Activation of the carboxylate group of 2%2C3-dihydroxy- benzoate (DHB)%2C via ATP-dependent PPi exchange reactions%2C to the acyladenylate. Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bao:BAMF_2994 2%2C3-dihydroxybenzoate-AMP ligase gene gene63 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00064 S100141_00065 S100141_00065 entB entB 56550 57476 + Isochorismatase Hydrolase%3B Phosphopantetheine%3B Phosphoprotein%3B Belongs to the isochorismatase family%3B Contains 1 acyl carrier domain%3B KEGG: bay:RBAM_029020 bifunctional isochorismate lyase / aryl carrier protein gene gene64 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00065 S100141_00066 S100141_00066 S100141_00066 57491 64618 + Linear gramicidin synthase subunit C Antibiotic biosynthesis%3B Isomerase%3B Ligase%3B Multifunctional enzyme%3B Phosphopantetheine%3B Phosphoprotein%3B Repeat%3B Activates the 7th to 12th amino acids (Val%2C D-Val%2C Trp%2C D-Leu%2C Xaa and D-Leu) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 8th (D-Val)%2C the 10th (D- Leu) and 12th (D-Leu) amino acids. The 11th (Xaa) amino acid is Trp in linear gramicidin%3B Phe in linear gramicidin B and Tyr in linear gramicidin C. Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 6 acyl carrier domains gene gene65 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00066 S100141_00067 S100141_00067 S100141_00067 64637 64852 + Protein MbtH Could be involved in mycobactin synthesis%3B To M. tuberculosis MbtH gene gene66 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00067 S100141_00068 S100141_00068 S100141_00068 64897 65574 - uncharacterized protein gene gene67 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00068 S100141_00069 S100141_00069 pntA pntA 65690 66820 - NAD(P)(+) transhydrogenase (Re/Si-specific) NAD%3B Oxidoreductase%3B May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer%3B Belongs to the AlaDH/PNT family%3B KEGG: eco:b1603 NAD(P) transhydrogenase subunit alpha gene gene68 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00069 S100141_00070 S100141_00070 S100141_00070 66924 68153 - Transcriptional activator AdeR Activator%3B DNA-binding%3B Sporulation%3B Transcription%3B Transcription regulation%3B Mediates ald expression in response to alanine availability and is important for normal sporulation in B. subtilis%3B Belongs to the CdaR family gene gene69 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00070 S100141_00071 S100141_00071 S100141_00071 68469 68762 + uncharacterized protein Coiled coil%3B Belongs to the ESAT-6 (esx) family gene gene70 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00071 S100141_00072 S100141_00072 S100141_00072 68832 69104 + putative ubiquitin-like protein YukD gene gene71 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00072 S100141_00073 S100141_00073 S100141_00073 69091 70434 + uncharacterized protein Cell membrane%3B Coiled coil%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the EssB family gene gene72 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00073 S100141_00074 S100141_00074 S100141_00074 70431 74906 + Ftsk domain-containing protein YukB ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Contains 2 FtsK domains gene gene73 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00074 S100141_00075 S100141_00075 S100141_00075 74903 75559 + Bacteriophage SPP1 adsorption protein YueB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Bacteriophage SPP1 receptor. Essential for the irreversible adsorption of the bacteriophage gene gene74 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00075 S100141_00076 S100141_00076 S100141_00076 75556 78027 + Bacteriophage SPP1 adsorption protein YueB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Bacteriophage SPP1 receptor. Essential for the irreversible adsorption of the bacteriophage gene gene75 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00076 S100141_00077 S100141_00077 S100141_00077 78029 78508 + uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix. gene gene76 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00077 S100141_00078 S100141_00078 yueD yueD 78569 78697 + Benzil reductase ((S)-benzoin forming) KEGG: bao:BAMF_2981 benzil reductase ((S)-benzoin forming) gene gene77 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00078 S100141_00079 S100141_00079 S100141_00079 78745 79299 + Benzil reductase ((S)-benzoin forming) Cytoplasm%3B NADP%3B Oxidoreductase%3B Reduces benzil stereospecifically to (S)-benzoin%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bao:BAMF_2981 benzil reductase ((S)-benzoin forming) gene gene78 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00079 S100141_00080 S100141_00080 S100141_00080 79464 79994 + Putative phosphohydrolase YueE Hydrolase%3B Contains 1 HD domain gene gene79 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00080 S100141_00081 S100141_00081 S100141_00081 80132 80368 + uncharacterized protein gene gene80 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00081 S100141_00082 S100141_00082 S100141_00082 80507 81610 + UPF0118 membrane protein YueF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0118 (PerM) family gene gene81 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00082 S100141_00083 S100141_00083 S100141_00083 81672 81893 + Spore germination protein-like protein YueG Belongs to the GerPA/GerPF family gene gene82 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00083 S100141_00084 S100141_00084 S100141_00084 81966 82214 + uncharacterized protein gene gene83 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00084 S100141_00085 S100141_00085 S100141_00085 82280 82678 + uncharacterized protein gene gene84 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00085 S100141_00086 S100141_00086 S100141_00086 82775 83326 + putative isochorismatase family protein PncA Hydrolase%3B Belongs to the isochorismatase family gene gene85 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00086 S100141_00087 S100141_00087 pncB pncB 83344 84810 + Nicotinate phosphoribosyltransferase Ligase%3B Pyridine nucleotide biosynthesis%3B Transferase%3B Catalyzes the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN)%3B Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP%3B Belongs to the NAPRTase family%3B KEGG: baq:BACAU_2910 nicotinate phosphoribosyltransferase gene gene86 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00087 S100141_00088 S100141_00088 S100141_00088 84940 86163 + uncharacterized protein Contains 1 EAL domain gene gene87 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00088 S100141_00089 S100141_00089 S100141_00089 86170 86511 - uncharacterized protein gene gene88 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00089 S100141_00090 S100141_00090 S100141_00090 86976 87116 + Degradation enzyme regulation protein DegQ Stimulates the phosphotransfer from phospho-DegS to DegU (By similarity). Affects protease and levansucrose production%3B Belongs to the DegQ family gene gene89 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00090 S100141_00091 S100141_00091 S100141_00091 87268 88110 + Competence regulatory protein ComQ Cell membrane%3B Competence%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Involved in the maturation of ComX%2C part of a major quorum-sensing system that regulates the development of genetic competence gene gene90 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00091 S100141_00092 S100141_00092 S100141_00092 88184 88360 + Competence pheromone Competence%3B Lipoprotein%3B Pheromone%3B Prenylation%3B Secreted%3B Sporulation%3B Part of a major quorum-sensing system that regulates the development of genetic competence. Acts through the activation of the two-component regulatory system ComP/ComA composed of a sensor histidine kinase%2C ComP%2C and a response regulator%2C ComA%2C that regulates directly the transcription of over 20 genes. Transport through the membrane may involve Spo0K. Under certain conditions plays a role in sporulation gene gene91 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00092 S100141_00093 S100141_00093 comP comP 88380 90689 + Histidine kinase ATP-binding%3B Cell membrane%3B Competence%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Sporulation%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Sensor in the two-component regulatory system ComP/ComA involved in a major quorum response pathway that regulates the development of genetic competence. Plays a role in sporulation%2C at least partly interchangeable with that of SpoIIJ. Probably activates ComA by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bama:RBAU_3007 two-component system%2C NarL family%2C sensor histidine kinase ComP gene gene92 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00093 S100141_00094 S100141_00094 S100141_00094 90784 91413 + Transcriptional regulatory protein ComA Activator%3B Competence%3B Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Response regulator in the two-component regulatory system ComP/ComA involved in a major quorum response pathway that regulates the development of genetic competence. Regulates directly the expression of over 20 genes%2C including genes of the srfA operon%2C degQ%2C rapA%2C rapC%2C rapE%2C rapF%2C etc. Regulates indirectly%2C through the regulation of comK transcription%2C the expression of late competence genes%3B Contains 1 HTH luxR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene93 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00094 S100141_00095 S100141_00095 menI menI 91435 91818 + 1%2C4-dihydroxy-2-naphthoyl-CoA hydrolase Hydrolase%3B Is not required for competence. Belongs to the thioesterase PaaI family%3B KEGG: yel:LC20_02935 1%2C4-dihydroxy-2-naphthoyl-CoA hydrolase gene gene94 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00095 S100141_00096 S100141_00096 S100141_00096 91858 92232 - UPF0091 protein Belongs to the UPF0091 family gene gene95 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00096 S100141_00097 S100141_00097 S100141_00097 92216 92500 - Na(+)/H(+) antiporter subunit Antiport%3B Cell membrane%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B. subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter%2C although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+)%2C Ca(2+) or Mg(2+). Involved in cholate and Na(+) efflux activities%2C which may be mechanistically coupled. Does not require other Mrp proteins for its own function. Belongs to the CPA3 antiporters (TC 2. A. 63) subunit F family%3B overlaps another CDS with the same product name gene gene96 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00097 S100141_00098 S100141_00098 S100141_00098 92500 92976 - Na(+)/H(+) antiporter subunit Antiport%3B Cell membrane%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mnh complex is a Na(+)Li(+)/H(+) antiporter involved in Na(+) and/or Li(+) excretion and Na(+) resistance. Na(+)/H(+) antiport consumes a transmembrane electrical potential%2C and is thus inferred to be electrogenic. Does not transport K(+)%2C Ca(2+) or Mg(2+). Mrp complex is a Na(+)/H(+) antiporter involved in Na(+) excretion and Na(+) resistance. Belongs to the CPA3 antiporters (TC 2. A. 63) subunit E family%3B overlaps another CDS with the same product name gene gene97 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00098 S100141_00099 S100141_00099 S100141_00099 92982 94472 - Na(+)/H(+) antiporter subunit D Antiport%3B Cell membrane%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B. subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter%2C although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+)%2C Ca(2+) or Mg(2+)%3B Belongs to the CPA3 antiporters (TC 2. A. 63) subunit D family gene gene98 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00099 S100141_00100 S100141_00100 S100141_00100 94575 94796 - Na(+)/H(+) antiporter subunit Antiport%3B Cell membrane%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B. subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter%2C although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+)%2C Ca(2+) or Mg(2+)%3B Belongs to the CPA3 antiporters (TC 2. A. 63) subunit C family%3B overlaps another CDS with the same product name gene gene99 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00100 S100141_00101 S100141_00101 S100141_00101 94796 95227 - Na(+)/H(+) antiporter subunit Antiport%3B Cell membrane%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B. subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter%2C although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+)%2C Ca(2+) or Mg(2+)%3B Belongs to the CPA3 antiporters (TC 2. A. 63) subunit B family%3B overlaps another CDS with the same product name gene gene100 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00101 S100141_00102 S100141_00102 S100141_00102 95224 97626 - Na(+)/H(+) antiporter subunit A1 Antiport%3B Cell membrane%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion%3B Belongs to the CPA3 antiporters (TC 2. A. 63) subunit A family gene gene101 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00102 S100141_00103 S100141_00103 S100141_00103 97870 98088 + hypothetical protein gene gene102 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00103 S100141_00104 S100141_00104 S100141_00104 98133 99092 - putative ABC transporter permease protein YufQ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system. Probably responsible for the translocation of the substrates across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family gene gene103 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00104 S100141_00105 S100141_00105 S100141_00105 99093 100139 - putative ABC transporter permease protein YufP Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily gene gene104 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00105 S100141_00106 S100141_00106 S100141_00106 100132 101664 - Monosaccharide-transporting ATPase ATP-binding%3B Nucleotide-binding%3B Repeat%3B Transport%3B Belongs to the ABC transporter superfamily%3B Contains 2 ABC transporter domains%3B KEGG: bsu:BSU31550 simple sugar transport system ATP-binding protein gene gene105 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00106 S100141_00107 S100141_00107 S100141_00107 101806 102879 - putative lipoprotein YufN Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Belongs to the BMP lipoprotein family gene gene106 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00107 S100141_00108 S100141_00108 S100141_00108 103281 103988 - Transcriptional regulatory protein DcuR Activator%3B Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system DcuR/DcuS. Involved in the C4-dicarboxylate-stimulated regulation of the genes encoding the anaerobic fumarate respiratory system (frdABC%3B nuoA%3B dcu%3B dcu%3B sdhCDA%3B etc.). Weakly regulates the aerobic C4-dicarboxylate transporter dctA (By similarity)%3B Contains 1 response regulatory domain gene gene107 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00108 S100141_00109 S100141_00109 yufL yufL 103981 105582 - Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of a two-component regulatory system MalK/MalR. Involved in the activation of maeA%2C maeN and yflS in presence of malate. Probably activates MalR by phosphorylation%3B Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bsu:BSU31520 two-component system%2C CitB family%2C sensor histidine kinase MalK gene gene108 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00109 S100141_00110 S100141_00110 S100141_00110 105757 106314 + putative membrane protein YufK Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene109 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00110 S100141_00111 S100141_00111 nagA nagA 106329 106742 - Alpha-N-acetylgalactosaminidase Belongs to the DCC thiol-disulfide oxidoreductase family%3B KEGG: dfa:DFA_08734 alpha-N-acetylgalactosaminidase gene gene110 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00111 S100141_00112 S100141_00112 S100141_00112 106764 108638 - Penicillin-binding protein Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Peptidoglycan synthesis%3B Signal%3B In the N-terminal sectio%3B belongs to the glycosyltransferase 51 family%3B In the C-terminal sectio%3B belongs to the transpeptidase family gene gene111 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00112 S100141_00113 S100141_00113 S100141_00113 108728 109972 - putative MFS-type transporter YuxJ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene112 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00113 S100141_00114 S100141_00114 S100141_00114 110123 110740 + putative 3'-5' exonuclease KapD Exonuclease%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nuclease%3B Sporulation%3B Specifically inhibits the KinA pathway to sporulation%3B Contains 1 exonuclease domain gene gene113 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00114 S100141_00115 S100141_00115 S100141_00115 110765 111151 - Kinase-associated lipoprotein Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal. gene gene114 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00115 S100141_00116 S100141_00116 kinB kinB 111199 111888 - Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Sporulation%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Phosphorylates the sporulation-regulatory proteins spo0A and spo0F. Spo0F is required for the KinB activity. Contains 1 histidine kinase domain%3B KEGG: bao:BAMF_2945 two-component system%2C sporulation sensor kinase B gene gene115 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00116 S100141_00117 S100141_00117 S100141_00117 112155 112481 - Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Sporulation%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Phosphorylates the sporulation-regulatory proteins spo0A and spo0F. Spo0F is required for the KinB activity. Contains 1 histidine kinase domain%3B KEGG: bsu:BSU31450 two-component system%2C sporulation sensor kinase B gene gene116 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00117 S100141_00118 S100141_00118 patB patB 112603 113766 - Cystathionine beta-lyase Amino-acid biosynthesis%3B Lyase%3B Methionine biosynthesis%3B Pyridoxal phosphate%3B Catalyzes the transformation of cystathionine to homocysteine. Also exhibits cysteine desulfhydrase activity in vitro%2C producing sulfide from cysteine. Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. MalY/PatB cystathionine beta-lyase subfamily%3B KEGG: bao:BAMF_2944 cystathione beta-lyase gene gene117 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00118 S100141_00119 S100141_00119 S100141_00119 113853 114113 + uncharacterized protein gene gene118 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00119 S100141_00120 S100141_00120 nicD nicD 114138 114959 - N-formylmaleamate deformylase Hydrolase%3B Serine esterase%3B Belongs to the DmpD/TodF/XylF esterase family%3B KEGG: bav:BAV2743 N-formylmaleamate deformylase gene gene119 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00120 S100141_00121 S100141_00121 S100141_00121 115112 115612 + putative HTH-type transcriptional regulator YugG DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH asnC-type DNA-binding domain gene gene120 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00121 S100141_00122 S100141_00122 S100141_00122 115613 116782 + Putative aminotransferase YugH Amino-acid biosynthesis%3B Aminotransferase%3B Cytoplasm%3B Pyridoxal phosphate%3B Transferase%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bao:BAMF_2940 aminotransferase%3B Transaminases gene gene121 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00122 S100141_00123 S100141_00123 S100141_00123 116979 117371 + General stress protein Cytoplasm%3B Stress response%3B Contains 1 S1 motif domain gene gene122 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00123 S100141_00124 S100141_00124 S100141_00124 117419 117655 - putative membrane protein YuzA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene123 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00124 S100141_00125 S100141_00125 S100141_00125 117886 119049 + putative NADH-dependent butanol dehydrogenase NAD%3B Oxidoreductase%3B Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: bsu:BSU31370 null%3B With NAD(+) or NADP(+) as acceptor gene gene124 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00125 S100141_00126 S100141_00126 S100141_00126 119136 119519 + putative NADH-dependent butanol dehydrogenase NAD%3B Oxidoreductase%3B Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: bsu:BSU31370 null%3B With NAD(+) or NADP(+) as acceptor gene gene125 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00126 S100141_00127 S100141_00127 yqhD yqhD 119571 120308 + putative NADH-dependent butanol dehydrogenase NAD%3B Oxidoreductase%3B Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: zmp:Zymop_1352 NADP-dependent alcohol dehydrogenase%3B Acting on the CH-OH group of donors gene gene126 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00127 S100141_00128 S100141_00128 S100141_00128 120502 121146 - uncharacterized protein Hydrolase. gene gene127 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00128 S100141_00129 S100141_00129 S100141_00129 121271 121837 - Chromate reductase Flavoprotein%3B FMN%3B NAD%3B NADP%3B Oxidoreductase%3B Involved in the protection against chromate toxicity. Catalyzes the transfer of three electrons to Cr(6+) producing Cr(3+) and one electron to molecular oxygen. This reaction produces transiently a minimal amount of the toxic Cr(5+) species and reactive oxygen species (ROS). It can also reduce quinones%2C potassium ferricyanide and 2%2C6-dichloroindophenol. The quinone reductase activity may protect against oxidative stress by preventing redox cycling of quinones which would otherwise generate ROS and by maintaining a pool of reduced quinone in the cell that is able to quench ROS directly. It displayed an eightfold preference for NADH over NADPH%3B Belongs to the SsuE family%3B KEGG: ssa:SSA_1386 null%3B With NAD(+) or NADP(+) as acceptor gene gene128 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00129 S100141_00130 S100141_00130 S100141_00130 122235 123587 + Glucose-6-phosphate isomerase Cytoplasm%3B Gluconeogenesis%3B Glycolysis%3B Isomerase%3B Phosphoprotein%3B Belongs to the GPI family%3B KEGG: bsu:BSU31350 glucose-6-phosphate isomerase gene gene129 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00130 S100141_00131 S100141_00131 S100141_00131 123653 124006 + hypothetical protein gene gene130 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00131 S100141_00132 S100141_00132 S100141_00132 124029 124265 + uncharacterized protein gene gene131 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00132 S100141_00133 S100141_00133 S100141_00133 124429 125415 - Putative potassium channel protein YugO Cell membrane%3B Ion channel%3B Ion transport%3B Membrane%3B Potassium%3B Potassium channel%3B Potassium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Contains 1 RCK N-terminal domain gene gene132 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00133 S100141_00134 S100141_00134 S100141_00134 125412 125666 - Protein mistic Cell membrane%3B Chaperone%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Chaperone that facilitates the production and integration of integral membrane proteins into the bacterial lipid bilayer gene gene133 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00134 S100141_00135 S100141_00135 S100141_00135 125799 126062 + putative membrane protein YuzI Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene134 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00135 S100141_00136 S100141_00136 S100141_00136 126109 126279 + Putative membrane protease YugP Cell membrane%3B Hydrolase%3B Membrane%3B Metal-binding%3B Metalloprotease%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Zinc. gene gene135 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00136 S100141_00137 S100141_00137 S100141_00137 126330 126785 + Putative membrane protease YugP Cell membrane%3B Hydrolase%3B Membrane%3B Metal-binding%3B Metalloprotease%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Zinc. gene gene136 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00137 S100141_00138 S100141_00138 S100141_00138 126828 128117 + UPF0053 protein YhdP CBS domain%3B Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0053 family%3B Contains 2 CBS domains%3B Contains 1 DUF21 domain gene gene137 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00138 S100141_00139 S100141_00139 malZ malZ 128207 129865 + Alpha-glucosidase Glycosidase%3B Hydrolase%3B Belongs to the glycosyl hydrolase 13 family%3B KEGG: bao:BAMF_2927 alpha-glucosidase gene gene138 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00139 S100141_00140 S100141_00140 ncd2 ncd2 129987 130409 + Nitronate monooxygenase Belongs to the UPF0047 family%3B KEGG: bao:BAMF_2926 nitronate monooxygenase%3B overlaps another CDS with the same product name gene gene139 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00140 S100141_00141 S100141_00141 S100141_00141 130402 131433 + Nitronate monooxygenase Flavoprotein%3B FMN%3B Monooxygenase%3B Oxidoreductase%3B Catalyzes the oxidation of alkyl nitronates to produce the corresponding carbonyl compounds and nitrites%3B Belongs to the nitronate monooxygenase family%3B KEGG: bao:BAMF_2926 nitronate monooxygenase%3B overlaps another CDS with the same product name gene gene140 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00141 S100141_00142 S100141_00142 S100141_00142 131456 131710 + uncharacterized protein gene gene141 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00142 S100141_00143 S100141_00143 S100141_00143 131604 132464 - Protein-glutamine gamma-glutamyltransferase Acyltransferase%3B Sporulation%3B Transferase%3B Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links. In wild-type spores at 37 degrees Celsius%2C tgl mediates the cross- linking of GerQ in higher molecular mass forms%2C probably in cooperation with YabG. Belongs to the bacillus TGase family%3B KEGG: bsu:BSU31270 protein-glutamine gamma-glutamyltransferase gene gene142 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00143 S100141_00144 S100141_00144 S100141_00144 132607 133497 + Methyl-accepting chemotaxis protein McpB Cell membrane%3B Chemotaxis%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpB is required for taxis towards asparagine%2C aspartate%2C glutamine%2C and histidine%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene143 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00144 S100141_00145 S100141_00145 S100141_00145 133503 134591 + Methyl-accepting chemotaxis protein McpA Cell membrane%3B Chemotaxis%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpA is required for taxis towards glucose and alpha-methylglucoside%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene144 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00145 S100141_00146 S100141_00146 S100141_00146 134775 136763 + Methyl-accepting chemotaxis protein TlpA Cell membrane%3B Chemotaxis%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene145 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00146 S100141_00147 S100141_00147 S100141_00147 136890 138494 + Methyl-accepting chemotaxis protein McpA Cell membrane%3B Chemotaxis%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpA is required for taxis towards glucose and alpha-methylglucoside%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene146 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00147 S100141_00148 S100141_00148 S100141_00148 138533 138874 + Methyl-accepting chemotaxis protein TlpA Cell membrane%3B Chemotaxis%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene147 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00148 S100141_00149 S100141_00149 S100141_00149 138989 140995 + Methyl-accepting chemotaxis protein McpB Cell membrane%3B Chemotaxis%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpB is required for taxis towards asparagine%2C aspartate%2C glutamine%2C and histidine%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene148 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00149 S100141_00150 S100141_00150 S100141_00150 141061 141585 + uncharacterized protein Belongs to the peptidase C56 family%3B Contains 1 PfpI endopeptidase domain%3B KEGG: dsa:Desal_2750 protease I%3B Glycosylases gene gene149 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00150 S100141_00151 S100141_00151 S100141_00151 141616 142602 - putative oxidoreductase YgjR Membrane%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: ecc:c3845 null%3B Oxidoreductases gene gene150 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00151 S100141_00152 S100141_00152 S100141_00152 142782 143942 + UPF0118 membrane protein YubA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0118 (PerM) family gene gene151 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00152 S100141_00153 S100141_00153 bacA bacA 144034 144864 + Undecaprenyl-diphosphate phosphatase Antibiotic resistance%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Membrane%3B Peptidoglycan synthesis%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin%3B Belongs to the UppP family%3B KEGG: bao:BAMF_2916 undecaprenyl-diphosphatase gene gene152 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00153 S100141_00154 S100141_00154 S100141_00154 144992 145063 + tRNA-Ala tRNA gene153 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00154 S100141_00155 S100141_00155 S100141_00155 145205 145753 + hypothetical protein gene gene154 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00155 S100141_00156 S100141_00156 S100141_00156 146333 146635 - uncharacterized protein gene gene155 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00156 S100141_00157 S100141_00157 S100141_00157 146642 148510 - Ribonuclease YobL Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 449-600) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YobK%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene156 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00157 S100141_00158 S100141_00158 S100141_00158 148938 149723 + hypothetical protein gene gene157 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00158 S100141_00159 S100141_00159 S100141_00159 149726 150091 + hypothetical protein gene gene158 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00159 S100141_00160 S100141_00160 S100141_00160 150326 150523 + hypothetical protein gene gene159 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00160 S100141_00161 S100141_00161 S100141_00161 151168 151809 - hypothetical protein gene gene160 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00161 S100141_00162 S100141_00162 yhb1 yhb1 152028 152681 + Nitric oxide dioxygenase Detoxification%3B FAD%3B Flavoprotein%3B Heme%3B Iron%3B Metal-binding%3B NAD%3B NADP%3B Oxidoreductase%3B Oxygen transport%3B Transport%3B Is involved in NO detoxification in an aerobic process%2C termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate%2C which protects the bacterium from various noxious nitrogen compounds. Therefore%2C plays a central role in the inducible response to nitrosative stress (By similarity)%3B Belongs to the globin family. Two-domain flavohemoproteins subfamily%3B In the C-terminal sectio%3B belongs to the flavoprotein pyridine nucleotide cytochrome reductase family%3B Contains 1 FAD-binding FR-type domain%3B KEGG: pseo:OM33_21110 nitric oxide dioxygenase gene gene161 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00162 S100141_00163 S100141_00163 S100141_00163 152827 153201 + Nitric oxide dioxygenase FAD%3B Flavoprotein%3B Heme%3B Iron%3B Metal-binding%3B NAD%3B NADP%3B Oxidoreductase%3B Oxygen transport%3B Transport%3B Belongs to the globin family. Two-domain flavohemoproteins subfamily%3B In the C-terminal sectio%3B belongs to the flavoprotein pyridine nucleotide cytochrome reductase family%3B Contains 1 FAD-binding FR-type domain%3B KEGG: mai:MICA_1640 nitric oxide dioxygenase gene gene162 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00163 S100141_00164 S100141_00164 S100141_00164 153343 154188 + N-acetylmuramoyl-L-alanine amidase Cell wall%3B Cell wall biogenesis/degradation%3B Glycosidase%3B Hydrolase%3B Magnesium%3B Secreted%3B Signal%3B Is the major glucosaminidase responsible for peptidoglycan structural determination during vegetative growth. Acts processively from the ends of the glycan strands. Also plays a role in motility%2C chemotaxis and cell division%3B Belongs to the glycosyl hydrolase 73 family%3B KEGG: lsa:LSA1558 N-acetylmuramoyl-L-alanine amidase gene gene163 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00164 S100141_00165 S100141_00165 S100141_00165 154222 154890 - Ktr system potassium uptake protein Cell membrane%3B Ion transport%3B Membrane%3B NAD%3B Potassium%3B Potassium transport%3B Transport%3B Catalytic subunit of the KtrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress%3B Belongs to the KtrA potassium transport family%3B Contains 1 RCK C-terminal domain%3B Contains 1 RCK N-terminal domain gene gene164 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00165 S100141_00166 S100141_00166 S100141_00166 155057 155593 - uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix%3B Required for complex colony architecture gene gene165 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00166 S100141_00167 S100141_00167 S100141_00167 155754 156308 - HTH-type transcriptional repressor GbsR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Negatively regulates the expression of the gbsAB and opuB operons. Required to control expression of these genes in response to choline availability. Also required to downregulate glycine betaine production once cellular adjustment to high osmolarity has been achieved%3B Belongs to the GbsR family gene gene166 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00167 S100141_00168 S100141_00168 betB betB 156509 157981 + Betaine-aldehyde dehydrogenase Chloroplast%3B NAD%3B Oxidoreductase%3B Plastid%3B Transit peptide%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: bao:BAMF_2872 betaine-aldehyde dehydrogenase gene gene167 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00168 S100141_00169 S100141_00169 gbsB gbsB 157999 159207 + Alcohol dehydrogenase Alternative initiation%3B NAD%3B Oxidoreductase%3B Essential for the utilization of choline as a precursor%3B Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: bsu:BSU31050 choline dehydrogenase gene gene168 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00169 S100141_00170 S100141_00170 S100141_00170 159279 159860 + Putative metal-sulfur cluster biosynthesis protein YuaD Contains 1 MOSC domain gene gene169 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00170 S100141_00171 S100141_00171 S100141_00171 159862 160350 - uncharacterized protein gene gene170 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00171 S100141_00172 S100141_00172 S100141_00172 160497 161027 + putative membrane protein YuaF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene171 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00172 S100141_00173 S100141_00173 S100141_00173 161047 162576 + uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix%3B To E. coli YqiK and Synechocystis PCC 6803 sll1021 gene gene172 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00173 S100141_00174 S100141_00174 S100141_00174 162607 163188 - Thiamine transporter ThiT Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably a thiamine-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane%2C not extracytoplasmic soluble proteins (By similarity)%3B Belongs to the ECF family. Thiamine transporter (TC 2. A. 88) subfamily gene gene173 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00174 S100141_00175 S100141_00175 S100141_00175 163755 165302 + 16S ribosomal RNA rRNA gene174 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00175 S100141_00176 S100141_00176 S100141_00176 165479 168409 + 23S ribosomal RNA rRNA gene175 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00176 S100141_00177 S100141_00177 S100141_00177 168580 168695 + 5S ribosomal RNA rRNA gene176 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00177 S100141_00178 S100141_00178 S100141_00178 168705 168779 + tRNA-Asn tRNA gene177 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00178 S100141_00179 S100141_00179 S100141_00179 168786 168877 + tRNA-Ser tRNA gene178 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00179 S100141_00180 S100141_00180 S100141_00180 168892 168966 + tRNA-Glu tRNA gene179 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00180 S100141_00181 S100141_00181 S100141_00181 169084 169159 + tRNA-Val tRNA gene180 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00181 S100141_00182 S100141_00182 S100141_00182 169181 169257 + tRNA-Met tRNA gene181 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00182 S100141_00183 S100141_00183 S100141_00183 169272 169348 + tRNA-Asp tRNA gene182 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00183 S100141_00184 S100141_00184 S100141_00184 169359 169434 + tRNA-Phe tRNA gene183 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00184 S100141_00185 S100141_00185 S100141_00185 169438 169510 + tRNA-Thr tRNA gene184 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00185 S100141_00186 S100141_00186 S100141_00186 169518 169602 + tRNA-Tyr tRNA gene185 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00186 S100141_00187 S100141_00187 S100141_00187 169610 169683 + tRNA-Trp tRNA gene186 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00187 S100141_00188 S100141_00188 S100141_00188 169704 169776 + tRNA-His tRNA gene187 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00188 S100141_00189 S100141_00189 S100141_00189 169785 169856 + tRNA-Gln tRNA gene188 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00189 S100141_00190 S100141_00190 S100141_00190 169910 169984 + tRNA-Gly tRNA gene189 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00190 S100141_00191 S100141_00191 S100141_00191 169998 170068 + tRNA-Cys tRNA gene190 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00191 S100141_00192 S100141_00192 S100141_00192 170079 170167 + tRNA-Leu tRNA gene191 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00192 S100141_00193 S100141_00193 S100141_00193 170353 171312 + Tyrosine recombinase XerC Cell cycle%3B Cell division%3B Chromosome partition%3B Cytoplasm%3B DNA integration%3B DNA recombination%3B DNA-binding%3B Site-specific tyrosine recombinase%2C which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids%3B Belongs to the 'phage' integrase family. XerC subfamily gene gene192 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00193 S100141_00194 S100141_00194 S100141_00194 171572 172501 + hypothetical protein gene gene193 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00194 S100141_00195 S100141_00195 S100141_00195 172518 172892 + hypothetical protein gene gene194 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00195 S100141_00196 S100141_00196 S100141_00196 173087 173434 + hypothetical protein gene gene195 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00196 S100141_00197 S100141_00197 S100141_00197 173412 173600 + hypothetical protein gene gene196 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00197 S100141_00198 S100141_00198 S100141_00198 173600 173923 + hypothetical protein gene gene197 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00198 S100141_00199 S100141_00199 S100141_00199 174098 174433 + hypothetical protein gene gene198 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00199 S100141_00200 S100141_00200 S100141_00200 174430 174675 + hypothetical protein gene gene199 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00200 S100141_00201 S100141_00201 S100141_00201 174675 174848 + hypothetical protein gene gene200 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00201 S100141_00202 S100141_00202 S100141_00202 174849 175175 + hypothetical protein gene gene201 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00202 S100141_00203 S100141_00203 S100141_00203 175175 175543 + hypothetical protein gene gene202 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00203 S100141_00204 S100141_00204 S100141_00204 175527 175910 + hypothetical protein gene gene203 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00204 S100141_00205 S100141_00205 S100141_00205 175927 176322 + hypothetical protein gene gene204 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00205 S100141_00206 S100141_00206 S100141_00206 176517 176663 + hypothetical protein gene gene205 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00206 S100141_00207 S100141_00207 S100141_00207 176682 177476 + hypothetical protein gene gene206 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00207 S100141_00208 S100141_00208 S100141_00208 177446 177946 + hypothetical protein gene gene207 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00208 S100141_00209 S100141_00209 S100141_00209 177946 178149 + hypothetical protein gene gene208 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00209 S100141_00210 S100141_00210 dnaB dnaB 178146 179495 + DNA helicase KEGG: bao:BAMF_0894 replicative DNA helicase gene gene209 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00210 S100141_00211 S100141_00211 S100141_00211 179517 180536 + hypothetical protein gene gene210 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00211 S100141_00212 S100141_00212 S100141_00212 180834 181031 - hypothetical protein gene gene211 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00212 S100141_00213 S100141_00213 S100141_00213 181140 182318 + hypothetical protein gene gene212 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00213 S100141_00214 S100141_00214 S100141_00214 182594 183208 + hypothetical protein gene gene213 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00214 S100141_00215 S100141_00215 S100141_00215 183345 183497 + hypothetical protein gene gene214 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00215 S100141_00216 S100141_00216 S100141_00216 183494 184018 + hypothetical protein gene gene215 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00216 S100141_00217 S100141_00217 S100141_00217 184266 185021 + hypothetical protein gene gene216 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00217 S100141_00218 S100141_00218 S100141_00218 185044 185475 + hypothetical protein gene gene217 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00218 S100141_00219 S100141_00219 S100141_00219 185516 186595 + hypothetical protein gene gene218 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00219 S100141_00220 S100141_00220 dpo1 dpo1 186801 189098 + DNA-directed DNA polymerase DNA damage%3B DNA repair%3B DNA replication%3B DNA-binding%3B DNA-directed DNA polymerase%3B Exonuclease%3B Hydrolase%3B Nuclease%3B Nucleotidyltransferase%3B Transferase%3B In addition to polymerase activity%2C this DNA polymerase exhibits 3' to 5' and 5' to 3' exonuclease activity. It is able to utilize nicked circular duplex DNA as a template and can unwind the parental DNA strand from its template. Belongs to the DNA polymerase type-A family%3B Contains 1 3'-5' exonuclease domain%3B Contains 1 5'-3' exonuclease domain%3B KEGG: bao:BAMF_0904 DNA polymerase I gene gene219 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00220 S100141_00221 S100141_00221 S100141_00221 189099 190148 + hypothetical protein gene gene220 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00221 S100141_00222 S100141_00222 S100141_00222 190148 190468 + hypothetical protein gene gene221 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00222 S100141_00223 S100141_00223 ruvC ruvC 190465 190983 + Crossover junction endodeoxyribonuclease KEGG: bao:BAMF_0908 crossover junction endodeoxyribonuclease RuvC gene gene222 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00223 S100141_00224 S100141_00224 S100141_00224 190989 191354 + hypothetical protein gene gene223 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00224 S100141_00225 S100141_00225 S100141_00225 191359 191616 + hypothetical protein gene gene224 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00225 S100141_00226 S100141_00226 S100141_00226 191613 191807 + hypothetical protein gene gene225 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00226 S100141_00227 S100141_00227 S100141_00227 191804 192004 + hypothetical protein gene gene226 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00227 S100141_00228 S100141_00228 S100141_00228 192001 192150 + hypothetical protein gene gene227 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00228 S100141_00229 S100141_00229 S100141_00229 192144 192506 + Protein NrdI Probably involved in ribonucleotide reductase function%3B Belongs to the NrdI family gene gene228 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00229 S100141_00230 S100141_00230 nrdA nrdA 192513 194612 + Ribonucleoside-diphosphate reductase Allosteric enzyme%3B ATP-binding%3B Disulfide bond%3B DNA replication%3B Nucleotide-binding%3B Oxidoreductase%3B Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase large chain family%3B KEGG: bao:BAMF_0912 ribonucleoside-diphosphate reductase alpha chain gene gene229 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00230 S100141_00231 S100141_00231 S100141_00231 194644 194976 + hypothetical protein gene gene230 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00231 S100141_00232 S100141_00232 nrdB nrdB 195015 195983 + Ribonucleoside-diphosphate reductase DNA replication%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase small chain family%3B KEGG: bamy:V529_20170 ribonucleoside-diphosphate reductase beta chain gene gene231 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00232 S100141_00233 S100141_00233 S100141_00233 196034 196615 + dUTP diphosphatase Hydrolase%3B Magnesium%3B Metal-binding%3B Nucleotide metabolism%3B This enzyme is involved in nucleotide metabolism: it produces dUMP%2C the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA%3B Belongs to the dUTPase family%3B KEGG: bao:BAMF_0916 dUTP pyrophosphatase gene gene232 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00233 S100141_00234 S100141_00234 S100141_00234 196615 196842 + hypothetical protein gene gene233 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00234 S100141_00235 S100141_00235 S100141_00235 196843 197013 + hypothetical protein gene gene234 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00235 S100141_00236 S100141_00236 S100141_00236 197234 197575 + SPBc2 prophage-derived uncharacterized protein YorM Signal. gene gene235 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00236 S100141_00237 S100141_00237 S100141_00237 197591 198655 + uncharacterized protein gene gene236 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00237 S100141_00238 S100141_00238 S100141_00238 198652 199212 + hypothetical protein gene gene237 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00238 S100141_00239 S100141_00239 S100141_00239 199201 199587 - hypothetical protein gene gene238 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00239 S100141_00240 S100141_00240 hsdM hsdM 199698 200972 + Site-specific DNA-methyltransferase (adenine-specific) KEGG: ftd:AS84_1540 type I restriction enzyme M protein gene gene239 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00240 S100141_00241 S100141_00241 S100141_00241 200972 201361 + hypothetical protein gene gene240 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00241 S100141_00242 S100141_00242 S100141_00242 201354 201842 + hypothetical protein gene gene241 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00242 S100141_00243 S100141_00243 S100141_00243 201931 202731 + hypothetical protein gene gene242 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00243 S100141_00244 S100141_00244 S100141_00244 202764 203075 - hypothetical protein gene gene243 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00244 S100141_00245 S100141_00245 S100141_00245 203087 204514 - hypothetical protein gene gene244 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00245 S100141_00246 S100141_00246 S100141_00246 204565 204909 + hypothetical protein gene gene245 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00246 S100141_00247 S100141_00247 S100141_00247 205046 205264 + hypothetical protein gene gene246 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00247 S100141_00248 S100141_00248 S100141_00248 206250 206528 + hypothetical protein gene gene247 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00248 S100141_00249 S100141_00249 S100141_00249 206518 206892 + hypothetical protein gene gene248 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00249 S100141_00250 S100141_00250 S100141_00250 206885 207433 + hypothetical protein gene gene249 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00250 S100141_00251 S100141_00251 S100141_00251 207434 207823 + hypothetical protein gene gene250 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00251 S100141_00252 S100141_00252 S100141_00252 208140 208439 + hypothetical protein gene gene251 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00252 S100141_00253 S100141_00253 S100141_00253 208442 208684 + hypothetical protein gene gene252 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00253 S100141_00254 S100141_00254 S100141_00254 208850 209188 + hypothetical protein gene gene253 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00254 S100141_00255 S100141_00255 S100141_00255 209307 209630 + hypothetical protein gene gene254 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00255 S100141_00256 S100141_00256 S100141_00256 209605 211386 + Putative terminase large subunit Viral genome packaging%3B Virus exit from host cell%3B Belongs to the phage terminase family gene gene255 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00256 S100141_00257 S100141_00257 S100141_00257 211398 212696 + hypothetical protein gene gene256 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00257 S100141_00258 S100141_00258 clpP clpP 212650 213396 + Endopeptidase Clp Cytoplasm%3B Hydrolase%3B Protease%3B Serine protease%3B Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins%3B Belongs to the peptidase S14 family%3B KEGG: bli:BL00880 ATP-dependent Clp protease%2C protease subunit gene gene257 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00258 S100141_00259 S100141_00259 S100141_00259 213396 214550 + hypothetical protein gene gene258 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00259 S100141_00260 S100141_00260 S100141_00260 214591 215088 + Chitinase Carbohydrate metabolism%3B Chitin degradation%3B Chitin-binding%3B Glycosidase%3B Hydrolase%3B Polysaccharide degradation%3B Signal%3B Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily%3B Contains 1 CBM2 (carbohydrate binding type-2) domain%3B Contains 1 fibronectin type-III domain gene gene259 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00260 S100141_00261 S100141_00261 S100141_00261 215091 215330 + hypothetical protein gene gene260 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00261 S100141_00262 S100141_00262 S100141_00262 215335 215670 + hypothetical protein gene gene261 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00262 S100141_00263 S100141_00263 S100141_00263 215667 216089 + hypothetical protein gene gene262 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00263 S100141_00264 S100141_00264 S100141_00264 216107 216430 + hypothetical protein gene gene263 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00264 S100141_00265 S100141_00265 S100141_00265 216439 217020 + hypothetical protein gene gene264 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00265 S100141_00266 S100141_00266 S100141_00266 216971 217285 + hypothetical protein gene gene265 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00266 S100141_00267 S100141_00267 S100141_00267 217336 217671 + hypothetical protein gene gene266 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00267 S100141_00268 S100141_00268 S100141_00268 217914 223214 + Tape measure protein Host membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Viral tail assembly%3B Virus exit from host cell%3B Plays a role in virion tail formation. The length of the tape measure protein is proportional to the length of the phage's tail gene gene267 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00268 S100141_00269 S100141_00269 S100141_00269 223215 224036 + hypothetical protein gene gene268 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00269 S100141_00270 S100141_00270 S100141_00270 224046 225572 + hypothetical protein gene gene269 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00270 S100141_00271 S100141_00271 S100141_00271 225615 227663 + hypothetical protein gene gene270 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00271 S100141_00272 S100141_00272 S100141_00272 227684 229123 + Phage-like element PBSX protein XkdV To B. subtilis YqcC gene gene271 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00272 S100141_00273 S100141_00273 S100141_00273 229136 229432 + hypothetical protein gene gene272 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00273 S100141_00274 S100141_00274 S100141_00274 229433 229627 + hypothetical protein gene gene273 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00274 S100141_00275 S100141_00275 S100141_00275 229631 229894 + hypothetical protein gene gene274 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00275 S100141_00276 S100141_00276 cwlA cwlA 229961 230896 + N-acetylmuramoyl-L-alanine amidase Cell wall biogenesis/degradation%3B Competence%3B Hydrolase%3B Secreted%3B Signal%3B Sporulation%3B Autolysins are involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella and sporulation%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B Contains 1 LysM repeat%3B KEGG: bli:BL00542 N-acetylmuramoyl-L-alanine amidase gene gene275 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00276 S100141_00277 S100141_00277 S100141_00277 230918 231175 + hypothetical protein gene gene276 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00277 S100141_00278 S100141_00278 S100141_00278 231264 231581 + hypothetical protein gene gene277 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00278 S100141_00279 S100141_00279 S100141_00279 231619 231885 - hypothetical protein gene gene278 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00279 S100141_00280 S100141_00280 tagE tagE 231906 233420 - Poly(glycerol-phosphate) alpha-glucosyltransferase Cell inner membrane%3B Cell membrane%3B Glycosyltransferase%3B Membrane%3B Transferase%3B Adds a GalNAc residue on to the Und-PP-Bac2%2C4diNAc- GalNAc disaccharide in the N-linked protein glycosylation pathway. Transfers the third sugar in the heptasaccharide biosynthesis%3B Belongs to the glycosyltransferase group 1 family%3B KEGG: bso:BSNT_02005 poly(glycerol-phosphate) alpha-glucosyltransferase gene gene279 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00280 S100141_00281 S100141_00281 S100141_00281 233484 233699 - hypothetical protein gene gene280 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00281 S100141_00282 S100141_00282 S100141_00282 233859 234677 + hypothetical protein gene gene281 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00282 S100141_00283 S100141_00283 S100141_00283 234750 235079 + hypothetical protein gene gene282 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00283 S100141_00284 S100141_00284 S100141_00284 235384 235468 + tRNA-Leu tRNA gene283 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00284 S100141_00285 S100141_00285 rapD rapD 235795 236073 + Response regulator aspartate phosphatase Hydrolase%3B Protein phosphatase%3B Repeat%3B TPR repeat%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bli:BL02513 response regulator aspartate phosphatase D%3B Acting on ester bonds gene gene284 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00285 S100141_00286 S100141_00286 S100141_00286 236293 236763 + Response regulator aspartate phosphatase D Hydrolase%3B Protein phosphatase%3B Repeat%3B TPR repeat%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bli:BL02513 response regulator aspartate phosphatase D%3B Acting on ester bonds gene gene285 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00286 S100141_00287 S100141_00287 S100141_00287 236818 236955 + hypothetical protein gene gene286 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00287 S100141_00288 S100141_00288 S100141_00288 239296 239511 + hypothetical protein gene gene287 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00288 S100141_00289 S100141_00289 S100141_00289 239484 239855 + N-acetylmuramoyl-L-alanine amidase Cell wall biogenesis/degradation%3B Hydrolase%3B Repeat%3B Secreted%3B Signal%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B KEGG: bli:BL01582 N-acetylmuramoyl-L-alanine amidase gene gene288 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00289 S100141_00290 S100141_00290 S100141_00290 239914 240252 - hypothetical protein gene gene289 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00290 S100141_00291 S100141_00291 S100141_00291 240278 242002 - Ribonuclease YxiD Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene290 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00291 S100141_00292 S100141_00292 S100141_00292 242268 242564 + hypothetical protein gene gene291 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00292 S100141_00293 S100141_00293 S100141_00293 242795 243235 - hypothetical protein gene gene292 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00293 S100141_00294 S100141_00294 S100141_00294 243252 244160 - hypothetical protein gene gene293 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00294 S100141_00295 S100141_00295 S100141_00295 244208 244810 - Ribonuclease YxiD Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene294 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00295 S100141_00296 S100141_00296 rapE rapE 245136 246326 + Response regulator aspartate phosphatase Hydrolase%3B Protein phosphatase%3B Repeat%3B Sporulation%3B TPR repeat%3B Prevents sporulation by dephosphorylating Spo0F%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bli:BL01908 response regulator aspartate phosphatase E%3B Acting on ester bonds gene gene295 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00296 S100141_00297 S100141_00297 tarS tarS 247046 248371 + Threonine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B Zinc%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: pod:PODO_08475 threonyl-tRNA synthetase gene gene296 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00297 S100141_00298 S100141_00298 aroD aroD 249224 249988 + 3-dehydroquinate dehydratase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Lyase%3B Schiff base%3B Involved in the third step of the chorismate pathway%2C which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate%3B Belongs to the type-I 3-dehydroquinase family%3B KEGG: bli:BL00001 3-dehydroquinate dehydratase I gene gene297 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00298 S100141_00299 S100141_00299 thiC thiC 250394 252169 + Phosphomethylpyrimidine synthase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Lyase%3B Metal-binding%3B S-adenosyl-L-methionine%3B Thiamine biosynthesis%3B Zinc%3B Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction%3B Belongs to the ThiC family%3B KEGG: bsu:BSU08790 phosphomethylpyrimidine synthase gene gene298 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00299 S100141_00300 S100141_00300 ssuB ssuB 252372 253139 + Aliphatic sulfonates import ATP-binding protein SsuB ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3. A. 1. 17. 2) family%3B Contains 1 ABC transporter domain%3B KEGG: bli:BL03206 sulfonate transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene299 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00300 S100141_00301 S100141_00301 S100141_00301 253160 254149 + Putative aliphatic sulfonates-binding protein Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B Part of a binding-protein-dependent transport system for aliphatic sulfonates. Putative binding protein. Belongs to the bacterial solute-binding protein SsuA/TauA family gene gene300 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00301 S100141_00302 S100141_00302 S100141_00302 254146 254982 + Putative aliphatic sulfonates transport permease protein SsuC Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of a binding-protein-dependent transport system for aliphatic sulfonates. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene301 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00302 S100141_00303 S100141_00303 ssuD ssuD 254996 256126 + Alkanesulfonate monooxygenase Flavoprotein%3B FMN%3B Monooxygenase%3B Oxidoreductase%3B Catalyzes the desulfonation of aliphatic sulfonates%3B Belongs to the SsuD family%3B KEGG: rme:Rmet_1371 alkanesulfonate monooxygenase gene gene302 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00303 S100141_00304 S100141_00304 S100141_00304 256157 256615 - putative lipoprotein YgaO Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transmembrane%3B Transmembrane helix. gene gene303 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00304 S100141_00305 S100141_00305 S100141_00305 256612 256818 - putative HTH-type transcriptional regulator YgzD DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene304 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00305 S100141_00306 S100141_00306 S100141_00306 257368 257580 + hypothetical protein gene gene305 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00306 S100141_00307 S100141_00307 potA potA 257688 258434 + Polyamine-transporting ATPase Amino-acid transport%3B ATP-binding%3B CBS domain%3B Nucleotide-binding%3B Repeat%3B Transport%3B Involved in a high affinity multicomponent binding- protein-dependent transport system for choline. Probably responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B Contains 2 CBS domains%3B KEGG: pkc:PKB_2225 spermidine/putrescine transport system ATP-binding protein gene gene306 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00307 S100141_00308 S100141_00308 S100141_00308 258400 259869 + hypothetical protein gene gene307 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00308 S100141_00309 S100141_00309 S100141_00309 259859 260767 + hypothetical protein gene gene308 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00309 S100141_00310 S100141_00310 S100141_00310 260764 261048 + hypothetical protein gene gene309 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00310 S100141_00311 S100141_00311 S100141_00311 261156 261425 + 30S ribosomal protein S14 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Binds 16S rRNA%2C required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site%3B Belongs to the ribosomal protein S14P family gene gene310 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00311 S100141_00312 S100141_00312 S100141_00312 261568 261641 + tRNA-Gly tRNA gene311 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00312 S100141_00313 S100141_00313 S100141_00313 261750 262379 - uncharacterized protein gene gene312 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00313 S100141_00314 S100141_00314 queG queG 262460 263608 + Epoxyqueuosine reductase 4Fe-4S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase%3B Queuosine biosynthesis%3B Repeat%3B tRNA processing%3B Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q)%2C which is a hypermodified base found in the wobble positions of tRNA(Asp)%2C tRNA(Asn)%2C tRNA(His) and tRNA(Tyr)%3B Belongs to the QueG family%3B Contains 2 4Fe-4S ferredoxin-type domains%3B KEGG: bli:BL03196 epoxyqueuosine reductase gene gene313 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00314 S100141_00315 S100141_00315 S100141_00315 263672 264577 + uncharacterized protein gene gene314 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00315 S100141_00316 S100141_00316 trmL trmL 264621 265094 + tRNA (cytidine(34)-2'-O)-methyltransferase Cytoplasm%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B tRNA processing%3B Could methylate the ribose at the nucleotide 34 wobble position in tRNA%3B Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily%3B KEGG: gpb:HDN1F_07340 tRNA (cytidine/uridine-2'-O-)-methyltransferase gene gene315 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00316 S100141_00317 S100141_00317 S100141_00317 265186 265800 + uncharacterized protein gene gene316 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00317 S100141_00318 S100141_00318 S100141_00318 265815 266525 + uncharacterized protein gene gene317 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00318 S100141_00319 S100141_00319 S100141_00319 266540 267241 + uncharacterized protein gene gene318 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00319 S100141_00320 S100141_00320 S100141_00320 267642 269537 + Protein PrkA Belongs to the PrkA family gene gene319 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00320 S100141_00321 S100141_00321 S100141_00321 269712 270398 + Stress response UPF0229 protein YhbH Stress response%3B Belongs to the UPF0229 family gene gene320 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00321 S100141_00322 S100141_00322 S100141_00322 270619 272211 - hypothetical protein gene gene321 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00322 S100141_00323 S100141_00323 S100141_00323 272383 272571 - hypothetical protein gene gene322 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00323 S100141_00324 S100141_00324 S100141_00324 272693 273577 - hypothetical protein gene gene323 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00324 S100141_00325 S100141_00325 S100141_00325 274220 274540 - hypothetical protein gene gene324 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00325 S100141_00326 S100141_00326 S100141_00326 274633 274779 - hypothetical protein gene gene325 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00326 S100141_00327 S100141_00327 S100141_00327 274958 275368 + hypothetical protein gene gene326 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00327 S100141_00328 S100141_00328 S100141_00328 276171 276608 + hypothetical protein gene gene327 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00328 S100141_00329 S100141_00329 S100141_00329 277298 277399 - hypothetical protein gene gene328 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00329 S100141_00330 S100141_00330 S100141_00330 277413 277913 - hypothetical protein gene gene329 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00330 S100141_00331 S100141_00331 S100141_00331 277941 278180 - hypothetical protein gene gene330 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00331 S100141_00332 S100141_00332 S100141_00332 278192 278695 - hypothetical protein gene gene331 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00332 S100141_00333 S100141_00333 S100141_00333 278697 278987 - hypothetical protein gene gene332 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00333 S100141_00334 S100141_00334 S100141_00334 279089 279289 - hypothetical protein gene gene333 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00334 S100141_00335 S100141_00335 S100141_00335 279367 279729 - hypothetical protein gene gene334 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00335 S100141_00336 S100141_00336 S100141_00336 279816 280271 - hypothetical protein gene gene335 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00336 S100141_00337 S100141_00337 S100141_00337 280291 280395 - hypothetical protein gene gene336 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00337 S100141_00338 S100141_00338 S100141_00338 280422 280595 - hypothetical protein gene gene337 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00338 S100141_00339 S100141_00339 S100141_00339 282019 282366 + hypothetical protein gene gene338 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00339 S100141_00340 S100141_00340 S100141_00340 282701 283468 + hypothetical protein gene gene339 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00340 S100141_00341 S100141_00341 S100141_00341 283794 283916 - hypothetical protein gene gene340 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00341 S100141_00342 S100141_00342 rapI rapI 283906 285027 - Response regulator aspartate phosphatase Hydrolase%3B Protein phosphatase%3B Repeat%3B TPR repeat%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bli:BL02161 response regulator aspartate phosphatase I%3B Acting on ester bonds gene gene341 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00342 S100141_00343 S100141_00343 S100141_00343 285258 285431 + uncharacterized protein gene gene342 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00343 S100141_00344 S100141_00344 S100141_00344 285600 287264 + Ribonuclease YxiD Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene343 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00344 S100141_00345 S100141_00345 S100141_00345 287286 287747 + hypothetical protein gene gene344 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00345 S100141_00346 S100141_00346 S100141_00346 287800 288264 + hypothetical protein gene gene345 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00346 S100141_00347 S100141_00347 S100141_00347 288395 289258 + hypothetical protein gene gene346 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00347 S100141_00348 S100141_00348 S100141_00348 289386 289631 + hypothetical protein gene gene347 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00348 S100141_00349 S100141_00349 S100141_00349 289696 289884 + hypothetical protein gene gene348 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00349 S100141_00350 S100141_00350 S100141_00350 289909 290148 + Putative uncharacterized protein ORFD in retron EC67 Transposable element%3B To phage P2 uncharacterized 12. 9 kDa protein in gpA 3'region gene gene349 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00350 S100141_00351 S100141_00351 S100141_00351 290170 290358 + hypothetical protein gene gene350 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00351 S100141_00352 S100141_00352 S100141_00352 290462 290674 + hypothetical protein gene gene351 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00352 S100141_00353 S100141_00353 S100141_00353 290671 290991 + hypothetical protein gene gene352 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00353 S100141_00354 S100141_00354 S100141_00354 290984 291340 + hypothetical protein gene gene353 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00354 S100141_00355 S100141_00355 S100141_00355 291436 292110 + SPBc2 prophage-derived UPF0714 protein YoqZ Belongs to the UPF0714 family gene gene354 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00355 S100141_00356 S100141_00356 S100141_00356 292285 294039 + SPBc2 prophage-derived uncharacterized protein YorA Repeat%3B Contains 13 PbH1 repeats gene gene355 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00356 S100141_00357 S100141_00357 S100141_00357 294259 294411 + hypothetical protein gene gene356 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00357 S100141_00358 S100141_00358 S100141_00358 294463 294690 + hypothetical protein gene gene357 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00358 S100141_00359 S100141_00359 S100141_00359 294635 294784 + hypothetical protein gene gene358 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00359 S100141_00360 S100141_00360 S100141_00360 294916 295662 + UPF0736 protein Belongs to the UPF0736 family gene gene359 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00360 S100141_00361 S100141_00361 S100141_00361 295655 296077 + dCMP deaminase Hydrolase%3B Metal-binding%3B Zinc%3B Dispensable for transformability. Belongs to the cytidine and deoxycytidylate deaminase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: blr:BRLA_c013630 dCMP deaminase gene gene360 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00361 S100141_00362 S100141_00362 S100141_00362 296061 296330 + Putative transition state regulator Abh DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 SpoVT-AbrB domain%3B To B. subtilis AbrB and SpoVT gene gene361 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00362 S100141_00363 S100141_00363 S100141_00363 296454 296687 + hypothetical protein gene gene362 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00363 S100141_00364 S100141_00364 S100141_00364 296690 296887 + hypothetical protein gene gene363 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00364 S100141_00365 S100141_00365 S100141_00365 297073 297474 + hypothetical protein gene gene364 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00365 S100141_00366 S100141_00366 S100141_00366 297471 297782 + hypothetical protein gene gene365 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00366 S100141_00367 S100141_00367 S100141_00367 297882 298664 + hypothetical protein gene gene366 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00367 S100141_00368 S100141_00368 S100141_00368 298674 299162 + hypothetical protein gene gene367 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00368 S100141_00369 S100141_00369 S100141_00369 299137 299838 + hypothetical protein gene gene368 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00369 S100141_00370 S100141_00370 S100141_00370 299852 300349 + hypothetical protein gene gene369 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00370 S100141_00371 S100141_00371 S100141_00371 300448 301092 + hypothetical protein gene gene370 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00371 S100141_00372 S100141_00372 S100141_00372 301221 301499 + hypothetical protein gene gene371 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00372 S100141_00373 S100141_00373 S100141_00373 301499 302056 + hypothetical protein gene gene372 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00373 S100141_00374 S100141_00374 S100141_00374 302079 302852 + hypothetical protein gene gene373 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00374 S100141_00375 S100141_00375 S100141_00375 302914 303216 - hypothetical protein gene gene374 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00375 S100141_00376 S100141_00376 S100141_00376 303695 304372 + hypothetical protein gene gene375 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00376 S100141_00377 S100141_00377 S100141_00377 304372 305958 + hypothetical protein gene gene376 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00377 S100141_00378 S100141_00378 S100141_00378 306051 307409 + hypothetical protein gene gene377 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00378 S100141_00379 S100141_00379 S100141_00379 307426 308475 + hypothetical protein gene gene378 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00379 S100141_00380 S100141_00380 S100141_00380 308496 308915 + hypothetical protein gene gene379 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00380 S100141_00381 S100141_00381 S100141_00381 308945 309874 + hypothetical protein gene gene380 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00381 S100141_00382 S100141_00382 S100141_00382 309947 310345 + hypothetical protein gene gene381 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00382 S100141_00383 S100141_00383 S100141_00383 310348 310710 + hypothetical protein gene gene382 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00383 S100141_00384 S100141_00384 S100141_00384 310710 310871 + hypothetical protein gene gene383 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00384 S100141_00385 S100141_00385 S100141_00385 310887 311393 + hypothetical protein gene gene384 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00385 S100141_00386 S100141_00386 S100141_00386 311735 312454 + hypothetical protein gene gene385 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00386 S100141_00387 S100141_00387 S100141_00387 312473 312943 + hypothetical protein gene gene386 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00387 S100141_00388 S100141_00388 S100141_00388 313206 313658 + hypothetical protein gene gene387 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00388 S100141_00389 S100141_00389 S100141_00389 313651 314148 + hypothetical protein gene gene388 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00389 S100141_00390 S100141_00390 S100141_00390 314155 314619 + hypothetical protein gene gene389 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00390 S100141_00391 S100141_00391 S100141_00391 314632 320592 + putative tape measure protein Antimicrobial%3B Bacteriolytic enzyme%3B Coiled coil%3B Degradation of host cell envelope components during virus entry%3B Degradation of host peptidoglycans during virus entry%3B Lyase%3B Viral genome ejection through host cell envelope%3B Viral penetration into host cytoplasm%3B Viral tail assembly%3B Virion%3B Virus entry into host cell%3B Virus exit from host cell%3B Serves as a base for tail tube protein polymerization and acts as a template for tail length determination. Exolysin involved in host peptidoglycan digestion necessary for viral DNA entry into the host cell (PubMed:14763988)%3B Belongs to the P2likevirus tape measure protein family gene gene390 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00391 S100141_00392 S100141_00392 S100141_00392 320592 320954 + hypothetical protein gene gene391 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00392 S100141_00393 S100141_00393 S100141_00393 320971 325080 + Tail fiber protein Coiled coil%3B Virion%3B Structural protein%2C a component of a tail fiber gene gene392 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00393 S100141_00394 S100141_00394 S100141_00394 325100 327502 + hypothetical protein gene gene393 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00394 S100141_00395 S100141_00395 S100141_00395 327523 328062 + hypothetical protein gene gene394 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00395 S100141_00396 S100141_00396 S100141_00396 328085 328534 + hypothetical protein gene gene395 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00396 S100141_00397 S100141_00397 S100141_00397 328648 328950 + hypothetical protein gene gene396 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00397 S100141_00398 S100141_00398 amiA amiA 328978 330057 + N-acetylmuramoyl-L-alanine amidase Cell wall biogenesis/degradation%3B Competence%3B Hydrolase%3B Secreted%3B Sporulation%3B Autolysins are involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella and sporulation. Involved in prophage SP-beta-mediated cell lysis%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B KEGG: psab:PSAB_06125 N-acetylmuramoyl-L-alanine amidase gene gene397 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00398 S100141_00399 S100141_00399 S100141_00399 330070 330354 + hypothetical protein gene gene398 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00399 S100141_00400 S100141_00400 S100141_00400 330432 330794 + hypothetical protein gene gene399 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00400 S100141_00401 S100141_00401 S100141_00401 330852 331472 + hypothetical protein gene gene400 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00401 S100141_00402 S100141_00402 S100141_00402 331484 332035 - hypothetical protein gene gene401 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00402 S100141_00403 S100141_00403 thyA thyA 332032 332880 - Thymidylate synthase Cytoplasm%3B Methyltransferase%3B Nucleotide biosynthesis%3B Transferase%3B Provides the sole de novo source of dTMP for DNA biosynthesis%3B Belongs to the thymidylate synthase family. Bacterial- type ThyA subfamily%3B KEGG: bsu:BSU17680 thymidylate synthase gene gene402 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00403 S100141_00404 S100141_00404 folA folA 332867 333382 - Dihydrofolate reductase Cell cycle%3B Cell division%3B Chromosome partition%3B Cytoplasm%3B Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)%3B Belongs to the ScpA family%3B Contains 1 DHFR (dihydrofolate reductase) domain%3B KEGG: xfa:XF2331 dihydrofolate reductase gene gene403 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00404 S100141_00405 S100141_00405 S100141_00405 333393 334124 - hypothetical protein gene gene404 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00405 S100141_00406 S100141_00406 S100141_00406 334203 334385 - hypothetical protein gene gene405 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00406 S100141_00407 S100141_00407 S100141_00407 334401 335411 - hypothetical protein gene gene406 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00407 S100141_00408 S100141_00408 S100141_00408 335414 335593 - hypothetical protein gene gene407 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00408 S100141_00409 S100141_00409 S100141_00409 335649 336989 - DNA helicase KEGG: sbw:TGUWTKB_3580 replicative DNA helicase gene gene408 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00409 S100141_00410 S100141_00410 S100141_00410 336982 337521 - Guanylate kinase KEGG: cbl:CLK_A0185 guanylate kinase gene gene409 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00410 S100141_00411 S100141_00411 S100141_00411 337551 338243 - hypothetical protein gene gene410 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00411 S100141_00412 S100141_00412 S100141_00412 338314 338526 - hypothetical protein gene gene411 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00412 S100141_00413 S100141_00413 S100141_00413 338519 338905 - hypothetical protein gene gene412 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00413 S100141_00414 S100141_00414 S100141_00414 338978 339262 - hypothetical protein gene gene413 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00414 S100141_00415 S100141_00415 S100141_00415 339327 339770 - hypothetical protein gene gene414 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00415 S100141_00416 S100141_00416 S100141_00416 339829 340497 - hypothetical protein ATP-binding%3B Cytoplasm%3B Nucleotide-binding%3B Belongs to the PhoH family gene gene415 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00416 S100141_00417 S100141_00417 S100141_00417 340529 341074 - hypothetical protein gene gene416 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00417 S100141_00418 S100141_00418 S100141_00418 341098 341637 - hypothetical protein gene gene417 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00418 S100141_00419 S100141_00419 S100141_00419 341667 342668 - hypothetical protein gene gene418 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00419 S100141_00420 S100141_00420 S100141_00420 342668 342916 - hypothetical protein gene gene419 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00420 S100141_00421 S100141_00421 S100141_00421 342980 343930 - hypothetical protein gene gene420 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00421 S100141_00422 S100141_00422 S100141_00422 344039 345079 - Ribonucleoside-diphosphate reductase DNA replication%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase small chain family%3B KEGG: bha:BH0502 ribonucleoside-diphosphate reductase beta chain gene gene421 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00422 S100141_00423 S100141_00423 S100141_00423 345154 347484 - Ribonucleoside-diphosphate reductase Allosteric enzyme%3B ATP-binding%3B Disulfide bond%3B DNA replication%3B Nucleotide-binding%3B Oxidoreductase%3B Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase large chain family%3B Contains 1 ATP-cone domain%3B KEGG: sml:Smlt2842 ribonucleoside-diphosphate reductase alpha chain gene gene422 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00423 S100141_00424 S100141_00424 S100141_00424 347496 347870 - hypothetical protein gene gene423 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00424 S100141_00425 S100141_00425 S100141_00425 347863 348111 - hypothetical protein gene gene424 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00425 S100141_00426 S100141_00426 S100141_00426 348116 348430 - hypothetical protein gene gene425 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00426 S100141_00427 S100141_00427 S100141_00427 348643 348822 - hypothetical protein gene gene426 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00427 S100141_00428 S100141_00428 S100141_00428 348911 349387 + UPF0229 protein Belongs to the UPF0229 family gene gene427 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00428 S100141_00429 S100141_00429 S100141_00429 349695 350327 + Putative efflux system component YhbJ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene428 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00429 S100141_00430 S100141_00430 S100141_00430 350367 351956 + Lincomycin resistance protein LmrB Antibiotic resistance%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Proton-dependent transporter. May mediate the efflux of lincomycin. Belongs to the major facilitator superfamily. EmrB family gene gene429 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00430 S100141_00431 S100141_00431 wrbA wrbA 351974 352504 + NAD(P)H dehydrogenase (quinone) Contains 1 flavodoxin-like domain%3B KEGG: bsl:A7A1_3824 NAD(P)H dehydrogenase (quinone) gene gene430 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00431 S100141_00432 S100141_00432 S100141_00432 352518 352850 + hypothetical protein gene gene431 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00432 S100141_00433 S100141_00433 S100141_00433 353631 353840 + hypothetical protein gene gene432 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00433 S100141_00434 S100141_00434 S100141_00434 353860 354783 + Monosaccharide-transporting ATPase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Phosphonate transport%3B Transport%3B Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3. A. 1. 9. 1) family%3B Contains 1 ABC transporter domain%3B KEGG: yen:YE0142 simple sugar transport system ATP-binding protein gene gene433 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00434 S100141_00435 S100141_00435 S100141_00435 354776 355717 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene434 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00435 S100141_00436 S100141_00436 S100141_00436 355791 356651 - putative transposase-like protein DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene435 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00436 S100141_00437 S100141_00437 S100141_00437 356621 356953 - hypothetical protein gene gene436 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00437 S100141_00438 S100141_00438 S100141_00438 357124 357324 - Cold shock protein CspB Activator%3B Cytoplasm%3B DNA-binding%3B Stress response%3B Transcription%3B Transcription regulation%3B Binds to the pentamer sequences ATTGG and CCAAT with highest affinity in single-stranded DNA%2C and also to other sequences. Has greater affinity for ATTGG than CCAAT. Can act as transcriptional activator of cold shock genes by recognizing putative ATTGG-box elements present in promoter regions of genes induced under cold shock conditions%3B Contains 1 CSD (cold-shock) domain gene gene437 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00438 S100141_00439 S100141_00439 S100141_00439 357841 358842 + Methionine import ATP-binding protein MetN Amino-acid transport%3B ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Methionine importer (TC 3. A. 1. 24) family%3B Contains 1 ABC transporter domain gene gene438 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00439 S100141_00440 S100141_00440 S100141_00440 358845 359495 + D-methionine transport system permease protein MetI Amino-acid transport%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system for D-methionine and the toxic methionine analog alpha-methyl- methionine. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene439 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00440 S100141_00441 S100141_00441 S100141_00441 359517 360335 + D-methionine-binding lipoprotein MetQ Amino-acid transport%3B Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B This protein is a component of a D-methionine permease%2C a binding protein-dependent%2C ATP-driven transport system%3B Belongs to the NlpA lipoprotein family gene gene440 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00441 S100141_00442 S100141_00442 S100141_00442 360462 361847 + L-cystine uptake protein TcyP Amino-acid transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mediates uptake of L-cystine%2C the oxidized form of L- cysteine%3B Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family gene gene441 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00442 S100141_00443 S100141_00443 S100141_00443 361893 362234 - hypothetical protein gene gene442 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00443 S100141_00444 S100141_00444 preP preP 362282 364078 - Prolyl oligopeptidase Aminopeptidase%3B Hydrolase%3B Protease%3B Serine protease%3B Signal%3B Exopeptidase that catalyzes the removal of dipeptide units (NH2-P2-P1- or -P1'-P2'-COOH) from the free amino or carboxy termini. Prefers substrates composed of bulky%2C hydrophobic amino acids at P1 and P1' positions. Has endopeptidase activity on N- terminally blocked peptide derivatives which contain aromatic amino acid residue at the P1 position. Exopeptidase activity is much higher than its endopeptidase activity%3B Belongs to the peptidase S9 family%3B KEGG: cps:CPS_3511 prolyl oligopeptidase gene gene443 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00444 S100141_00445 S100141_00445 S100141_00445 364224 364784 + Lipoprotein YhcN Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Sporulation. gene gene444 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00445 S100141_00446 S100141_00446 S100141_00446 364900 365793 + uncharacterized protein Signal. gene gene445 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00446 S100141_00447 S100141_00447 S100141_00447 365787 366434 - Spore coat protein F-like protein YhcQ Sporulation%3B Belongs to the CotF family gene gene446 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00447 S100141_00448 S100141_00448 S100141_00448 367106 369130 + Protein-glutamate O-methyltransferase Contains 1 cheB-type methylesterase domain%3B Contains 1 cheR-type methyltransferase domain%3B KEGG: bae:BATR1942_02185 two-component system%2C chemotaxis family%2C CheB/CheR fusion protein gene gene447 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00448 S100141_00449 S100141_00449 S100141_00449 369243 372863 + 5'-nucleotidase Calcium%3B Endonuclease%3B Hydrolase%3B Manganese%3B Metal-binding%3B Nuclease%3B Nucleotide-binding%3B Signal%3B Sugar-nonspecific endonuclease that yields nucleotide 3'-monophosphate products. No 5'-nucleotidase activity was detected%2C using 5'-AMP as the substrate%2C in the presence of diverse divalent metals and with various pH values. In the C-terminal sectio%3B belongs to the 5'- nucleotidase family%3B Contains 1 TNase-like domain%3B KEGG: bha:BH1015 5'-nucleotidase gene gene448 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00449 S100141_00450 S100141_00450 srtA srtA 372860 373450 + Sortase A Membrane%3B Transmembrane%3B Transmembrane helix%3B KEGG: bli:BL03172 sortase A gene gene449 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00450 S100141_00451 S100141_00451 rluD rluD 373533 374450 - 23S rRNA pseudouridine(1911/1915/1917) synthase Isomerase%3B RNA-binding%3B Belongs to the pseudouridine synthase RluA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: bli:BL03158 23S rRNA pseudouridine1911/1915/1917 synthase gene gene450 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00451 S100141_00452 S100141_00452 S100141_00452 374563 374931 + uncharacterized protein gene gene451 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00452 S100141_00453 S100141_00453 S100141_00453 375100 375525 + CBS domain-containing protein YhcV CBS domain%3B Repeat%3B Contains 2 CBS domains gene gene452 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00453 S100141_00454 S100141_00454 S100141_00454 375664 376326 + uncharacterized protein Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family gene gene453 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00454 S100141_00455 S100141_00455 S100141_00455 376348 377886 + Hydrolase YhcX Hydrolase%3B Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family%3B Contains 1 CN hydrolase domain%3B Contains 1 N-acetyltransferase domain gene gene454 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00455 S100141_00456 S100141_00456 S100141_00456 377982 378116 + hypothetical protein gene gene455 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00456 S100141_00457 S100141_00457 S100141_00457 378222 379850 + Zinc import ATP-binding protein ZnuC ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Ion transport%3B Membrane%3B Nucleotide-binding%3B Transport%3B Zinc%3B Zinc transport%3B Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Zinc importer (TC 3. A. 1. 15. 5) family%3B Contains 1 ABC transporter domain gene gene456 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00457 S100141_00458 S100141_00458 S100141_00458 380099 380899 + putative transporter YrhG Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the FNT transporter (TC 2. A. 44) family gene gene457 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00458 S100141_00459 S100141_00459 S100141_00459 381466 382377 + putative transporter Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the auxin efflux carrier (TC 2. A. 69) family gene gene458 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00459 S100141_00460 S100141_00460 S100141_00460 382484 383476 - putative zinc-type alcohol dehydrogenase-like protein YogA Oxidoreductase%3B Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily gene gene459 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00460 S100141_00461 S100141_00461 S100141_00461 383653 384210 + Glycerol uptake operon antiterminator regulatory protein Glycerol metabolism%3B RNA-binding%3B Transcription%3B Transcription regulation%3B Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA. May also regulate expression of the glpFK operon gene gene460 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00461 S100141_00462 S100141_00462 S100141_00462 384440 385255 + Glycerol uptake facilitator protein Cell membrane%3B Glycerol metabolism%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Glycerol enters the cell via the glycerol diffusion facilitator protein. This membrane protein facilitates the movement of glycerol across the cytoplasmic membrane. Belongs to the MIP/aquaporin (TC 1. A. 8) family gene gene461 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00462 S100141_00463 S100141_00463 glpK glpK 385298 386788 + Glycerol kinase ATP-binding%3B Glycerol metabolism%3B Kinase%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate%3B Belongs to the FGGY kinase family%3B KEGG: pha:PSHAa0190 glycerol kinase gene gene462 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00463 S100141_00464 S100141_00464 S100141_00464 386766 386960 + hypothetical protein gene gene463 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00464 S100141_00465 S100141_00465 glpA glpA 386935 388602 + Glycerol-3-phosphate dehydrogenase Cytoplasm%3B FAD%3B Flavoprotein%3B Glycerol metabolism%3B Oxidoreductase%3B Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family%3B KEGG: bli:BL02902 glycerol-3-phosphate dehydrogenase gene gene464 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00465 S100141_00466 S100141_00466 S100141_00466 388787 390535 + Phosphoglucomutase (alpha-D-glucose-1%2C6-bisphosphate-dependent) Carbohydrate metabolism%3B Glucose metabolism%3B Isomerase%3B Magnesium%3B Metal-binding%3B Phosphoprotein%3B Catalyzes the interconversion between glucose-6- phosphate and alpha-glucose-1-phosphate. This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG)%2C i. e. the predominant glycolipid found in B. subtilis membrane%2C which is also used as a membrane anchor for lipoteichoic acid (LTA). Has a role in the biosynthesis of all phosphate-containing envelope polymers%2C since glucose-1-phosphate is the precursor of UDP-glucose%2C which serves as a glucosyl donor not only for the biosynthesis of LTA but also for wall teichoic acids (WTAs). Is required for biofilm formation. This is likely due to another role of UDP-glucose%2C which might also act as a metabolic signal regulating biofilm formation or may be involved in some unknown biosynthetic pathway essential for biofilm formation%2C e. g. the synthesis of an exopolysaccharide%3B Belongs to the phosphohexose mutase family%3B KEGG: bli:BL02901 phosphoglucomutase gene gene465 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00466 S100141_00467 S100141_00467 S100141_00467 390657 391115 + uncharacterized protein gene gene466 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00467 S100141_00468 S100141_00468 S100141_00468 391137 391334 + putative HTH-type transcriptional regulator DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene467 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00468 S100141_00469 S100141_00469 S100141_00469 391454 392602 + Histidine kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Two-component regulatory system%3B Member of the two-component regulatory system YhcY/YhcZ. Probably activates YhcZ by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bli:BL02898 two-component system%2C NarL family%2C sensor kinase gene gene468 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00469 S100141_00470 S100141_00470 S100141_00470 392590 393243 + Chemotaxis response regulator protein-glutamate methylesterase Chemotaxis%3B Cytoplasm%3B Hydrolase%3B Phosphoprotein%3B Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene469 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00470 S100141_00471 S100141_00471 S100141_00471 393248 393766 + Azobenzene reductase Flavoprotein%3B FMN%3B NADP%3B Oxidoreductase%3B Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADPH%2C but not NADH%2C as an electron donor for its activity%3B Belongs to the azoreductase type 2 family%3B KEGG: bli:BL02896 azobenzene reductase gene gene470 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00471 S100141_00472 S100141_00472 S100141_00472 393796 394044 - uncharacterized protein gene gene471 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00472 S100141_00473 S100141_00473 S100141_00473 394163 394567 + uncharacterized protein Signal. gene gene472 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00473 S100141_00474 S100141_00474 S100141_00474 394598 395029 - HTH-type transcriptional repressor NsrR 2Fe-2S%3B DNA-binding%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity%3B Contains 1 HTH rrf2-type DNA-binding domain gene gene473 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00474 S100141_00475 S100141_00475 S100141_00475 395287 396501 + Nitric oxide dioxygenase Cytoplasm%3B Detoxification%3B FAD%3B Flavoprotein%3B Heme%3B Iron%3B Metal-binding%3B NAD%3B NADP%3B Oxidoreductase%3B Oxygen transport%3B Transport%3B Is involved in NO detoxification in an aerobic process%2C termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate%2C which protects the cell from various noxious nitrogen compounds. Therefore%2C plays a central role in the inducible response to nitrosative stress%3B In the presence of oxygen and NADH%2C it has NADH oxidase activity%2C which leads to the generation of superoxide and H(2)O(2). Under anaerobic conditions%2C it also exhibits nitric oxide reductase and FAD reductase activities. However%2C all these reactions are much lower than NOD activity (By similarity)%3B Belongs to the globin family. Two-domain flavohemoproteins subfamily%3B In the C-terminal sectio%3B belongs to the flavoprotein pyridine nucleotide cytochrome reductase family%3B Contains 1 FAD-binding FR-type domain%3B KEGG: cps:CPS_0848 nitric oxide dioxygenase gene gene474 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00475 S100141_00476 S100141_00476 S100141_00476 396806 398215 + Stage V sporulation protein Sporulation%3B Appears to be involved in spore cortex formation. To E. coli YcgB gene gene475 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00476 S100141_00477 S100141_00477 lytE lytE 398630 399463 + putative peptidoglycan endopeptidase LytE Cell wall%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Protease%3B Repeat%3B Secreted%3B Signal%3B Thiol protease%3B Cell wall hydrolase that cleaves gamma-D-glutamate-meso- diaminopimelate bonds in peptidoglycan (By similarity). Seems to play a role in cell separation during vegetative growth%3B Belongs to the peptidase C40 family%3B Contains 3 LysM repeats%3B KEGG: bsu:BSU09420 peptidoglycan endopeptidase LytE%3B Acting on peptide bonds (peptidases) gene gene476 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00477 S100141_00478 S100141_00478 S100141_00478 399511 400389 - HTH-type transcriptional regulator CitR Cytoplasm%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Negative regulatory protein for the citA gene for citrate synthase I%3B Contains 1 HTH lysR-type DNA-binding domain gene gene477 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00478 S100141_00479 S100141_00479 gltA gltA 400500 401591 + Citrate (Si)-synthase Allosteric enzyme%3B Transferase%3B Tricarboxylic acid cycle%3B Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect. Belongs to the citrate synthase family%3B KEGG: bli:BL02891 citrate synthase gene gene478 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00479 S100141_00480 S100141_00480 S100141_00480 401714 402778 + Quinoprotein glucose dehydrogenase (PQQ%2C quinone) KEGG: tth:TTC0202 quinoprotein glucose dehydrogenase gene gene479 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00480 S100141_00481 S100141_00481 S100141_00481 402857 403726 + putative oxidoreductase YhdF Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bli:BL02889 null%3B Oxidoreductases gene gene480 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00481 S100141_00482 S100141_00482 S100141_00482 403865 405223 + Sodium-dependent neutral amino acid transporter B(0)AT2 Amino-acid transport%3B Glycoprotein%3B Ion transport%3B Membrane%3B Neurotransmitter transport%3B Phosphoprotein%3B Sodium%3B Sodium transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Functions as a sodium-dependent neutral amino acid transporter. Exhibits preference for methionine and for the branched-chain amino acids%2C particularly leucine%2C valine and isoleucine. Mediates the saturable%2C pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1:1. May have a role as transporter for neurotransmitter precursors into neurons. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2. A. 22) family. SLC6A15 subfamily gene gene481 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00482 S100141_00483 S100141_00483 gadB gadB 405245 406873 + Glutamate decarboxylase Decarboxylase%3B Lyase%3B Neurotransmitter biosynthesis%3B Phosphoprotein%3B Pyridoxal phosphate%3B Catalyzes the production of GABA%3B Belongs to the group II decarboxylase family%3B KEGG: olu:OSTLU_36228 glutamate decarboxylase gene gene482 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00483 S100141_00484 S100141_00484 S100141_00484 406911 407798 - putative HTH-type transcriptional regulator YdeE Cytoplasm%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH araC/xylS-type DNA-binding domain gene gene483 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00484 S100141_00485 S100141_00485 S100141_00485 407876 409288 - putative HTH-type transcriptional regulator YdeL Aminotransferase%3B DNA-binding%3B Pyridoxal phosphate%3B Transcription%3B Transcription regulation%3B Transferase%3B In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene484 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00485 S100141_00486 S100141_00486 S100141_00486 409401 409835 + putative N-acetyltransferase YhdJ Acyltransferase%3B Transferase%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: reh:H16_B1407 null%3B Transferring groups other than amino-acyl groups gene gene485 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00486 S100141_00487 S100141_00487 S100141_00487 409864 410154 - putative anti-sigma-M factor YhdK Cell membrane%3B Membrane%3B Repressor%3B Transcription%3B Transcription regulation%3B Transmembrane%3B Transmembrane helix. gene gene486 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00487 S100141_00488 S100141_00488 S100141_00488 410142 411212 - putative anti-sigma-M factor YhdL Membrane%3B Repressor%3B Transcription%3B Transcription regulation%3B Transmembrane%3B Transmembrane helix. gene gene487 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00488 S100141_00489 S100141_00489 S100141_00489 411205 411696 - RNA polymerase sigma factor SigM DNA-binding%3B Sigma factor%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor may be involved in the maintenance of membrane and cell wall integrity in response to salt%2C acid and ethanol stress. Belongs to the sigma-70 factor family. ECF subfamily gene gene488 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00489 S100141_00490 S100141_00490 S100141_00490 411986 412528 - uncharacterized protein ATP-binding%3B Nucleotide-binding. gene gene489 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00490 S100141_00491 S100141_00491 S100141_00491 412649 412921 + hypothetical protein gene gene490 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00491 S100141_00492 S100141_00492 plsC plsC 412987 413586 + 1-acylglycerol-3-phosphate O-acyltransferase Acyltransferase%3B Cell membrane%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) by incorporating an acyl moiety at the 2 position. This enzyme utilizes acyl-ACP as fatty acyl donor%2C but not acyl-CoA%3B Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family%3B KEGG: blh:BaLi_c11330 1-acyl-sn-glycerol-3-phosphate acyltransferase gene gene491 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00492 S100141_00493 S100141_00493 S100141_00493 413543 413686 + hypothetical protein gene gene492 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00493 S100141_00494 S100141_00494 S100141_00494 413748 414113 + Inner membrane protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B To E. coli YhaH gene gene493 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00494 S100141_00495 S100141_00495 S100141_00495 414144 415421 - Bile acid-CoA:amino acid N-acyltransferase Acyltransferase%3B Fatty acid metabolism%3B Hydrolase%3B Lipid metabolism%3B Peroxisome%3B Phosphoprotein%3B Serine esterase%3B Transferase%3B Involved in bile acid metabolism. In liver hepatocytes catalyzes the second step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi. The major components of bile are cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl-CoA thioester%2C either in peroxisomes (primary bile acids deriving from the cholesterol pathway)%2C or cytoplasmic at the endoplasmic reticulum (secondary bile acids). May catalyze the conjugation of primary or secondary bile acids%2C or both. The conjugation increases the detergent properties of bile acids in the intestine%2C which facilitates lipid and fat-soluble vitamin absorption. In turn%2C bile acids are deconjugated by bacteria in the intestine and are recycled back to the liver for reconjugation (secondary bile acids). May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro%2C catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH)%2C and conjugates glycine to these acyl-CoAs (By similarity)%3B Belongs to the C/M/P thioester hydrolase family gene gene494 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00495 S100141_00496 S100141_00496 S100141_00496 415418 416014 - putative HTH-type transcriptional regulator YvkB DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH tetR-type DNA-binding domain gene gene495 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00496 S100141_00497 S100141_00497 S100141_00497 416145 417464 - UPF0053 protein YhdP CBS domain%3B Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0053 family%3B Contains 2 CBS domains%3B Contains 1 DUF21 domain gene gene496 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00497 S100141_00498 S100141_00498 S100141_00498 417525 417950 - HTH-type transcriptional regulator CueR Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Transcriptional activator of the copZA operon%3B Contains 1 HTH merR-type DNA-binding domain gene gene497 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00498 S100141_00499 S100141_00499 S100141_00499 418054 418224 - hypothetical protein gene gene498 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00499 S100141_00500 S100141_00500 S100141_00500 418265 419638 + UPF0053 protein YhdT CBS domain%3B Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0053 family%3B Contains 2 CBS domains%3B Contains 1 DUF21 domain gene gene499 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00500 S100141_00501 S100141_00501 S100141_00501 419736 420137 + hypothetical protein gene gene500 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00501 S100141_00502 S100141_00502 S100141_00502 420346 420633 + hypothetical protein gene gene501 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00502 S100141_00503 S100141_00503 S100141_00503 420596 421273 + N-acetylmuramoyl-L-alanine amidase Cell wall%3B Cell wall biogenesis/degradation%3B Competence%3B Hydrolase%3B Metal-binding%3B Repeat%3B Secreted%3B Sporulation%3B Zinc%3B Autolysins are involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella - in particular of its basal body - and sporulation. CwlC is able to hydrolyze type A cell walls such as B. subtilis. Its main function is to lyze the mother cell wall peptidoglycan%2C playing a role during sporulation%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B Contains 1 SPOR domain%3B KEGG: bsu:BSU17410 N-acetylmuramoyl-L-alanine amidase gene gene502 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00503 S100141_00504 S100141_00504 S100141_00504 421443 421799 - Putative fluoride ion transporter CrcB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Important for reducing fluoride concentration in the cell%2C thus reducing its toxicity%3B Belongs to the CrcB (TC 9. B. 71) family%3B overlaps another CDS with the same product name gene gene503 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00504 S100141_00505 S100141_00505 S100141_00505 421796 422194 - Putative fluoride ion transporter CrcB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Important for reducing fluoride concentration in the cell%2C thus reducing its toxicity%3B Belongs to the CrcB (TC 9. B. 71) family%3B overlaps another CDS with the same product name gene gene504 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00505 S100141_00506 S100141_00506 glpQ glpQ 422210 422914 - Glycerophosphodiester phosphodiesterase Calcium%3B Glycerol metabolism%3B Hydrolase%3B Metal-binding%3B Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to sn-glycerol 3-phosphate (G3P) and the corresponding alcohols%3B Belongs to the glycerophosphoryl diester phosphodiesterase family%3B Contains 1 GP-PDE domain%3B KEGG: fau:Fraau_3181 glycerophosphoryl diester phosphodiesterase gene gene505 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00506 S100141_00507 S100141_00507 S100141_00507 423106 423213 + uncharacterized protein gene gene506 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00507 S100141_00508 S100141_00508 S100141_00508 423397 424473 + putative MscS family protein YhdY Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B May play a role in resistance to osmotic downshock%3B Belongs to the MscS (TC 1. A. 23) family gene gene507 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00508 S100141_00509 S100141_00509 npdA npdA 424502 425251 + NAD-dependent protein deacetylase Cytoplasm%3B Hydrolase%3B Metal-binding%3B NAD%3B Zinc%3B NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form%3B Belongs to the sirtuin family. Class U subfamily%3B Contains 1 deacetylase sirtuin-type domain%3B KEGG: bli:BL02876 NAD-dependent deacetylase%3B In linear amides gene gene508 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00509 S100141_00510 S100141_00510 S100141_00510 425372 426802 + hypothetical protein gene gene509 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00510 S100141_00511 S100141_00511 S100141_00511 426838 427332 - hypothetical protein gene gene510 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00511 S100141_00512 S100141_00512 S100141_00512 427467 428378 - Chitin deacetylase Cell membrane%3B Hydrolase%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the polysaccharide deacetylase family%3B KEGG: bcz:BCZK1658 chitin deacetylase gene gene511 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00512 S100141_00513 S100141_00513 S100141_00513 428676 429527 + D-amino-acid transaminase Aminotransferase%3B Pyridoxal phosphate%3B Transferase%3B Acts on the D-isomers of alanine%2C leucine%2C aspartate%2C glutamate%2C aminobutyrate%2C norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction. The second half-reaction is the reverse of the first%2C transferring the amino group from the pyridoxamine to a second alpha-keto acid to form the product D- amino acid via a ping-pong mechanism. This is an important process in the formation of D-alanine and D-glutamate%2C which are essential bacterial cell wall components (By similarity)%3B Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bli:BL02875 D-alanine transaminase gene gene512 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00513 S100141_00514 S100141_00514 S100141_00514 429566 430924 - Na(+)/H(+) antiporter NhaC Antiport%3B Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Na(+)/H(+) antiporter. Involved in pH homeostasis and sodium extrusion%3B Belongs to the NhaC Na(+)/H(+) (TC 2. A. 35) antiporter family gene gene513 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00514 S100141_00515 S100141_00515 galM galM 431160 432140 + Aldose 1-epimerase Carbohydrate metabolism%3B Isomerase%3B Belongs to the aldose epimerase family%3B KEGG: bli:BL02874 aldose 1-epimerase gene gene514 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00515 S100141_00516 S100141_00516 S100141_00516 432156 432632 - uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix. gene gene515 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00516 S100141_00517 S100141_00517 S100141_00517 432706 434640 - hypothetical protein gene gene516 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00517 S100141_00518 S100141_00518 S100141_00518 434640 436493 - hypothetical protein gene gene517 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00518 S100141_00519 S100141_00519 S100141_00519 437678 438178 - Stress response protein NhaX Stress response%3B Belongs to the universal stress protein A family gene gene518 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00519 S100141_00520 S100141_00520 S100141_00520 438699 440453 + putative multidrug resistance ABC transporter ATP-binding/permease protein YheI Antibiotic resistance%3B ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the transport of four structurally unrelated drugs%2C including doxorubicin and mitoxantrone. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene519 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00520 S100141_00521 S100141_00521 S100141_00521 440450 442468 + putative multidrug resistance ABC transporter ATP-binding/permease protein YheH Antibiotic resistance%3B ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the transport of four structurally unrelated drugs%2C including doxorubicin and mitoxantrone. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene520 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00521 S100141_00522 S100141_00522 S100141_00522 442488 443135 - uncharacterized protein gene gene521 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00522 S100141_00523 S100141_00523 S100141_00523 443132 443275 - hypothetical protein gene gene522 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00523 S100141_00524 S100141_00524 S100141_00524 443446 443649 - Small%2C acid-soluble spore protein DNA-binding%3B Sporulation%3B SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. Belongs to the alpha/beta-type SASP family gene gene523 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00524 S100141_00525 S100141_00525 S100141_00525 443885 444109 + hypothetical protein gene gene524 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00525 S100141_00526 S100141_00526 S100141_00526 444155 445261 - Phosphonates import ATP-binding protein PhnC ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Phosphonate transport%3B Transport%3B Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3. A. 1. 9. 1) family%3B Contains 1 ABC transporter domain gene gene525 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00526 S100141_00527 S100141_00527 S100141_00527 445377 446258 - uncharacterized protein Coiled coil. gene gene526 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00527 S100141_00528 S100141_00528 S100141_00528 446277 446486 - uncharacterized protein gene gene527 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00528 S100141_00529 S100141_00529 S100141_00529 446639 447997 - Endospore coat-associated protein YheD Membrane%3B Sporulation%3B Involved in sporulation%3B Belongs to the YheC/YheD family gene gene528 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00529 S100141_00530 S100141_00530 S100141_00530 447994 449079 - Endospore coat-associated protein YheC Membrane%3B Sporulation%3B Involved in sporulation%3B Belongs to the YheC/YheD family gene gene529 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00530 S100141_00531 S100141_00531 S100141_00531 449409 450539 + UPF0754 membrane protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0754 family gene gene530 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00531 S100141_00532 S100141_00532 S100141_00532 450662 451015 + UPF0342 protein Belongs to the UPF0342 family gene gene531 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00532 S100141_00533 S100141_00533 S100141_00533 451462 452325 + Stress response protein YhaX Stress response. gene gene532 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00533 S100141_00534 S100141_00534 hemN hemN 452354 453973 + Coproporphyrinogen dehydrogenase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase%3B Porphyrin biosynthesis%3B S-adenosyl-L-methionine%3B Involved in the biosynthesis of porphyrin-containing compound%3B Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemZ subfamily%3B KEGG: bli:BL02869 oxygen-independent coproporphyrinogen III oxidase gene gene533 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00534 S100141_00535 S100141_00535 S100141_00535 454055 455266 - K(+)/H(+) antiporter YhaU Antiport%3B Cell membrane%3B Ion transport%3B Membrane%3B Potassium%3B Potassium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Potassium/proton antiporter that mediates the efflux of potassium ions from the cell. Potassium antiport activity requires the presence of KhtT. Has higher activity at alkaline pH. Can also mediate rubidium/proton antiport. Has no permeability for sodium or lithium ions%3B Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2. A. 37) family gene gene534 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00535 S100141_00536 S100141_00536 S100141_00536 455273 455770 - K(+)/H(+) antiporter subunit KhtT Cell membrane%3B Membrane%3B Modulates the activity of the potassium/proton antiporter YhaU. The transporter is composed of the integral membrane protein YhaU and the regulatory protein KhtT%3B Contains 1 RCK C-terminal domain gene gene535 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00536 S100141_00537 S100141_00537 S100141_00537 455835 456164 - hypothetical protein gene gene536 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00537 S100141_00538 S100141_00538 liuC liuC 456365 457141 + Methylglutaconyl-CoA hydratase Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the enoyl-CoA hydratase/isomerase family%3B KEGG: mro:MROS_2743 methylglutaconyl-CoA hydratase gene gene537 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00538 S100141_00539 S100141_00539 rapJ rapJ 457496 458179 + Response regulator aspartate phosphatase Hydrolase%3B Protein phosphatase%3B Repeat%3B Sporulation%3B TPR repeat%3B Prevents sporulation by dephosphorylating Spo0F%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bsu:BSU02820 response regulator aspartate phosphatase J%3B Acting on ester bonds gene gene538 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00539 S100141_00540 S100141_00540 S100141_00540 458335 458472 + hypothetical protein gene gene539 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00540 S100141_00541 S100141_00541 S100141_00541 458477 458755 + hypothetical protein gene gene540 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00541 S100141_00542 S100141_00542 S100141_00542 458828 459013 - uncharacterized protein gene gene541 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00542 S100141_00543 S100141_00543 rbsA rbsA 459131 460027 + Monosaccharide-transporting ATPase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Phosphonate transport%3B Plasmid%3B Transport%3B Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3. A. 1. 9. 1) family%3B Contains 1 ABC transporter domain%3B KEGG: sod:Sant_0208 ribose transport system ATP-binding protein gene gene542 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00543 S100141_00544 S100141_00544 S100141_00544 460020 461288 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B To M. jannaschii MJ1024 gene gene543 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00544 S100141_00545 S100141_00545 S100141_00545 461408 462634 + putative metallophosphoesterase YhaO Hydrolase%3B Metal-binding%3B Belongs to the metallophosphoesterase superfamily gene gene544 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00545 S100141_00546 S100141_00546 S100141_00546 462648 465614 + uncharacterized protein Cell membrane%3B Coiled coil%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene545 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00546 S100141_00547 S100141_00547 cbf1 cbf1 465664 466608 + 3'-5' exoribonuclease YhaM DNA-binding%3B Exonuclease%3B Hydrolase%3B Nuclease%3B Shows a 3'-5' exoribonuclease activity%3B Belongs to the YhaM family%3B Contains 1 HD domain%3B Contains 1 OB DNA-binding domain%3B KEGG: bsu:BSU09930 3'-5' exoribonuclease%3B Acting on ester bonds gene gene546 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00547 S100141_00548 S100141_00548 S100141_00548 466677 466910 + Sporulation protein YhaL Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Required for efficient sporulation gene gene547 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00548 S100141_00549 S100141_00549 prsA prsA 466956 467816 - Peptidylprolyl isomerase Cell membrane%3B Isomerase%3B Lipoprotein%3B Membrane%3B Palmitate%3B Rotamase%3B Signal%3B Essential protein that plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins. Has PPIase activity but it is not essential for its function in vivo%3B Belongs to the PrsA family%3B Contains 1 PpiC domain%3B KEGG: bsu:BSU09950 foldase protein PrsA gene gene548 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00549 S100141_00550 S100141_00550 S100141_00550 468194 468292 + hypothetical protein gene gene549 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00550 S100141_00551 S100141_00551 S100141_00551 468639 469154 - putative membrane protein YhaJ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene550 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00551 S100141_00552 S100141_00552 S100141_00552 469368 469715 + uncharacterized protein gene gene551 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00552 S100141_00553 S100141_00553 S100141_00553 469712 470332 - HTH-type transcriptional regulator Hpr DNA-binding%3B Repressor%3B Sporulation%3B Transcription%3B Transcription regulation%3B Negative regulator of protease production and sporulation%3B Contains 1 HTH marR-type DNA-binding domain gene gene552 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00553 S100141_00554 S100141_00554 S100141_00554 470526 470882 - putative membrane protein YhaH Cell membrane%3B Coiled coil%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene553 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00554 S100141_00555 S100141_00555 S100141_00555 471044 471235 + putative membrane protein YhzF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene554 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00555 S100141_00556 S100141_00556 S100141_00556 471326 471853 - putative tryptophan transport protein Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably involved in tryptophan uptake. Belongs to the TrpP transporter family gene gene555 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00556 S100141_00557 S100141_00557 serC serC 471996 473117 - Phosphoserine transaminase Amino-acid biosynthesis%3B Aminotransferase%3B Cytoplasm%3B Pyridoxal phosphate%3B Serine biosynthesis%3B Transferase%3B Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily%3B KEGG: bsu:BSU10020 phosphoserine aminotransferase gene gene556 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00557 S100141_00558 S100141_00558 S100141_00558 473268 473687 - Protein HitA Contains 1 HIT domain gene gene557 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00558 S100141_00559 S100141_00559 S100141_00559 474215 474955 + Polar-amino-acid-transporting ATPase ATP-binding%3B Competence%3B Nucleotide-binding%3B Sporulation%3B Transport%3B Has a role in exoprotein production%2C sporulation and competence. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: cama:F384_08655 polar amino acid transport system ATP-binding protein gene gene558 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00559 S100141_00560 S100141_00560 S100141_00560 474948 476174 + Protein EcsB Cell membrane%3B Competence%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Presumed to form part of an ABC-transporter%2C it may form a transport channel gene gene559 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00560 S100141_00561 S100141_00561 S100141_00561 476223 476933 + Protein EcsC gene gene560 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00561 S100141_00562 S100141_00562 S100141_00562 476964 478184 - Putative amidohydrolase YhaA Cobalt%3B Hydrolase%3B Metal-binding%3B Zinc%3B Belongs to the peptidase M20A family%3B KEGG: tep:TepRe1_0059 amidohydrolase%3B In linear amides gene gene561 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00562 S100141_00563 S100141_00563 S100141_00563 478266 479639 - putative membrane protein YhfA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene562 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00563 S100141_00564 S100141_00564 S100141_00564 479748 480251 - Heme-degrading monooxygenase HmoB Cytoplasm%3B Heme%3B Iron%3B Metal-binding%3B Monooxygenase%3B Oxidoreductase%3B Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase%2C with subsequent release of free iron%3B Belongs to the antibiotic biosynthesis monooxygenase family%3B Contains 1 ABM domain gene gene563 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00564 S100141_00565 S100141_00565 S100141_00565 480384 482522 + Penicillin-binding protein 1F Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Peptidoglycan synthesis%3B Signal-anchor%3B Transmembrane%3B Transmembrane helix%3B Cell wall formation. May be involved in outgrowth of the germinated spore or it could function in the synthesis of the germ cell wall. In the N-terminal sectio%3B belongs to the glycosyltransferase 51 family%3B In the C-terminal sectio%3B belongs to the transpeptidase family%3B KEGG: bli:BL01071 penicillin-binding protein 2A%3B Peptidoglycan glycosyltransferase gene gene564 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00565 S100141_00566 S100141_00566 hemE hemE 482648 483709 + Uroporphyrinogen decarboxylase Cytoplasm%3B Decarboxylase%3B Lyase%3B Porphyrin biosynthesis%3B Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III%3B Belongs to the uroporphyrinogen decarboxylase family%3B KEGG: bli:BL01072 uroporphyrinogen decarboxylase gene gene565 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00566 S100141_00567 S100141_00567 hemH hemH 483783 484721 + Protoporphyrin ferrochelatase Cytoplasm%3B Heme biosynthesis%3B Iron%3B Lyase%3B Metal-binding%3B Porphyrin biosynthesis%3B Catalyzes the ferrous insertion into protoporphyrin IX%3B Belongs to the ferrochelatase family%3B KEGG: bsu:BSU10130 ferrochelatase gene gene566 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00567 S100141_00568 S100141_00568 ppoX ppoX 484737 486149 + Protoporphyrinogen oxidase Cytoplasm%3B FAD%3B Flavoprotein%3B Oxidoreductase%3B Porphyrin biosynthesis%3B Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. Also oxidizes the pathway intermediate coproporphyrinogen-III%3B Belongs to the protoporphyrinogen oxidase family%3B KEGG: bli:BL01074 oxygen-dependent protoporphyrinogen oxidase gene gene567 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00568 S100141_00569 S100141_00569 S100141_00569 486346 486918 + putative HTH-type transcriptional regulator YhgD DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH tetR-type DNA-binding domain gene gene568 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00569 S100141_00570 S100141_00570 S100141_00570 486992 489154 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B To L. lactis phage infection protein (PIP) gene gene569 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00570 S100141_00571 S100141_00571 fabH fabH 489210 490205 - Beta-ketoacyl-[acyl-carrier-protein] synthase III Acyltransferase%3B Cytoplasm%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Multifunctional enzyme%3B Transferase%3B Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and/or straight-chain of fatty acids%3B Belongs to the FabH family%3B KEGG: bli:BL01107 3-oxoacyl-(acyl-carrier-protein) synthase III gene gene570 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00571 S100141_00572 S100141_00572 S100141_00572 490312 491349 + Cellulase Aminopeptidase%3B Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Belongs to the peptidase M42 family%3B KEGG: tpe:Tpen_0002 endoglucanase gene gene571 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00572 S100141_00573 S100141_00573 S100141_00573 491428 491625 - hypothetical protein gene gene572 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00573 S100141_00574 S100141_00574 S100141_00574 491787 493073 - Proton/sodium-glutamate symport protein Cell membrane%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B This carrier protein is part of the Na(+)-dependent%2C binding-protein-independent glutamate-aspartate transport system%3B Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family gene gene573 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00574 S100141_00575 S100141_00575 S100141_00575 493381 493515 - uncharacterized protein gene gene574 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00575 S100141_00576 S100141_00576 S100141_00576 493672 494406 + putative metallo-hydrolase YhfI Hydrolase%3B Metal-binding%3B Zinc%3B Belongs to the metallo-beta-lactamase superfamily gene gene575 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00576 S100141_00577 S100141_00577 lplA lplA 494425 495414 + Lipoate--protein ligase ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Transferase%3B Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. Is also able to use octanoate as substrate%3B Belongs to the LplA family%3B Contains 1 BPL/LPL catalytic domain%3B KEGG: bsu:BSU10250 lipoate-protein ligase A gene gene576 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00577 S100141_00578 S100141_00578 acsL acsL 495577 497118 + Long-chain-fatty-acid--CoA ligase ATP-binding%3B Fatty acid metabolism%3B Ligase%3B Lipid degradation%3B Lipid metabolism%3B Nucleotide-binding%3B Involved in the degradation of long-chain fatty acids. Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bli:BL01080 long-chain acyl-CoA synthetase gene gene577 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00578 S100141_00579 S100141_00579 S100141_00579 497089 497556 - hypothetical protein gene gene578 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00579 S100141_00580 S100141_00580 S100141_00580 497663 498214 + HTH-type transcriptional regulator SutR Activator%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Regulates the expression of 12-16 transcription units involved in various steps of sulfur utilization. Represses expression of pfkB%2C fliZ%2C cysE%2C ydcO and its own expression. Activates expression of ypfN. Acts by binding to SutR boxes%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene579 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00580 S100141_00581 S100141_00581 S100141_00581 498227 498943 + putative membrane protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the AzlC family gene gene580 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00581 S100141_00582 S100141_00582 S100141_00582 498936 499247 + hypothetical protein gene gene581 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00582 S100141_00583 S100141_00583 S100141_00583 499319 500575 + Ste24 endopeptidase Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Zinc%3B Belongs to the peptidase M48B family%3B KEGG: tte:TTE0991 STE24 endopeptidase gene gene582 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00583 S100141_00584 S100141_00584 aprE aprE 500633 501772 - Subtilisin Calcium%3B Hydrolase%3B Metal-binding%3B Protease%3B Secreted%3B Serine protease%3B Signal%3B Sporulation%3B Zymogen%3B Subtilisin is an extracellular alkaline serine protease%2C it catalyzes the hydrolysis of proteins and peptide amides. Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bli:BL01111 subtilisin gene gene583 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00584 S100141_00585 S100141_00585 S100141_00585 502183 503082 + putative transporter YdeD Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene584 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00585 S100141_00586 S100141_00586 S100141_00586 503190 504167 + Putative ABC transporter substrate-binding lipoprotein YhfQ Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene585 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00586 S100141_00587 S100141_00587 S100141_00587 504250 505248 + Iron(3+)-hydroxamate import system permease protein FhuG Cell membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex FhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene586 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00587 S100141_00588 S100141_00588 S100141_00588 505248 506276 + Fe(3+)-citrate import system permease protein YfmD Cell membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex YfmCDEF involved in citrate-dependent Fe(3+) import. Involved in the translocation of the substrate across the membrane (Probable)%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene587 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00588 S100141_00589 S100141_00589 S100141_00589 506289 506861 - putative phosphatase PhoE Hydrolase%3B Phosphatase with broad substrate specificity. Does not have phosphoglycerate mutase activity%3B Belongs to the phosphoglycerate mutase family. GpmB subfamily gene gene588 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00589 S100141_00590 S100141_00590 S100141_00590 507146 508438 - Heme-based aerotactic transducer HemAT Heme%3B Iron%3B Metal-binding%3B Transducer%3B Heme-containing signal transducer responsible for aerotaxis%2C the migratory response toward or away from oxygen%3B Contains 1 methyl-accepting transducer domain gene gene589 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00590 S100141_00591 S100141_00591 S100141_00591 508545 510074 - Putative Rieske 2Fe-2S iron-sulfur protein YhfW 2Fe-2S%3B Disulfide bond%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase%3B Contains 1 Rieske domain%3B KEGG: ctc:CTC00417 null%3B With NAD(+) or NADP(+) as acceptor gene gene590 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00591 S100141_00592 S100141_00592 S100141_00592 510215 511072 + putative oxidoreductase YhxC Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bld:BLi01117 null%3B Oxidoreductases gene gene591 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00592 S100141_00593 S100141_00593 S100141_00593 511138 511371 - uncharacterized protein gene gene592 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00593 S100141_00594 S100141_00594 S100141_00594 511644 512222 + Competence transcription factor Activator%3B Competence%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Intermediate regulatory gene required for the expression of the late competence genes comC%2C comE%2C comG and the bdbDC operon. Receives signals from SrfA%2C and possibly other regulatory COM genes%2C and transduces these signals to the late COM genes gene gene593 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00594 S100141_00595 S100141_00595 S100141_00595 512216 512581 - uncharacterized protein Coiled coil. gene gene594 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00595 S100141_00596 S100141_00596 S100141_00596 512790 513401 + putative membrane protein YhjE Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene595 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00596 S100141_00597 S100141_00597 lepB lepB 513414 513932 + Signal peptidase I Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Belongs to the peptidase S26 family%3B KEGG: bli:BL01092 signal peptidase I gene gene596 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00597 S100141_00598 S100141_00598 S100141_00598 514087 515862 - Minor extracellular protease Epr Hydrolase%3B Protease%3B Secreted%3B Serine protease%3B Signal%3B Zymogen%3B Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bli:BL01118 minor extracellular protease Epr%3B Serine endopeptidases gene gene597 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00598 S100141_00599 S100141_00599 S100141_00599 516237 517478 + putative sulfoacetate transporter SauU Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B May transport sulfoacetate into the cell%3B Belongs to the major facilitator superfamily gene gene598 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00599 S100141_00600 S100141_00600 S100141_00600 517507 519120 - Purine catabolism regulatory protein Activator%3B DNA-binding%3B Purine metabolism%3B Repressor%3B Transcription%3B Transcription regulation%3B Activates the expression of pucFG%2C pucH%2C pucI%2C pucJKLM and guaD%2C while it represses pucABCDE and its own expression%3B Belongs to the CdaR family gene gene599 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00600 S100141_00601 S100141_00601 S100141_00601 519274 519363 + hypothetical protein gene gene600 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00601 S100141_00602 S100141_00602 dpyS dpyS 519949 521313 + Dihydropyrimidinase Hydrolase%3B Metal-binding%3B Purine metabolism%3B Zinc%3B Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring%3B Belongs to the DHOase family. Allantoinase subfamily%3B KEGG: mey:TM49_03535 dihydropyrimidinase gene gene601 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00602 S100141_00603 S100141_00603 S100141_00603 521981 523168 + Allantoate deiminase Hydrolase%3B Metal-binding%3B Purine metabolism%3B Zinc%3B Involved in the anaerobic utilization of allantoin. Converts allantoate to (S)-ureidoglycolate and ammonia%3B Belongs to the peptidase M20 family%3B KEGG: bli:BL01095 allantoate deiminase gene gene602 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00603 S100141_00604 S100141_00604 ylbA ylbA 523192 523980 + (S)-ureidoglycine aminohydrolase Cytoplasm%3B Hydrolase%3B Manganese%3B Metal-binding%3B Purine metabolism%3B Involved in the catabolism of purine nucleotides. Catalyzes the second%2C stereospecific hydrolysis reaction of the allantoin degradation pathway%2C producing S-ureidoglycolate and ammonia from S-ureidoglycine%3B Belongs to the UGHY family%3B KEGG: bli:BL01096 (S)-ureidoglycine aminohydrolase gene gene603 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00604 S100141_00605 S100141_00605 allD allD 523996 525024 + Ureidoglycolate dehydrogenase (NAD(+)) Cytoplasm%3B NAD%3B Oxidoreductase%3B Purine metabolism%3B Involved in the anaerobic utilization of allantoin. Belongs to the LDH2/MDH2 oxidoreductase family%3B KEGG: bli:BL01097 ureidoglycolate dehydrogenase (NAD+) gene gene604 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00605 S100141_00606 S100141_00606 S100141_00606 525048 525836 + Ureidoglycolate dehydrogenase (NAD(+)) Cytoplasm%3B NAD%3B Oxidoreductase%3B Purine metabolism%3B Involved in the anaerobic utilization of allantoin. Belongs to the LDH2/MDH2 oxidoreductase family%3B KEGG: yin:CH53_61 ureidoglycolate dehydrogenase (NAD+) gene gene605 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00606 S100141_00607 S100141_00607 S100141_00607 525846 526097 + Ureidoglycolate dehydrogenase (NAD(+)) Cytoplasm%3B NAD%3B Oxidoreductase%3B Purine metabolism%3B Involved in the anaerobic utilization of allantoin. Belongs to the LDH2/MDH2 oxidoreductase family%3B KEGG: sty:STY0576 ureidoglycolate dehydrogenase (NAD+) gene gene606 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00607 S100141_00608 S100141_00608 S100141_00608 526115 527872 + uncharacterized protein To E. coli FdrA and some%2C to bacterial SucD%3B overlaps another CDS with the same product name gene gene607 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00608 S100141_00609 S100141_00609 S100141_00609 527872 529137 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B To E. coli YlbE%3B overlaps another CDS with the same product name gene gene608 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00609 S100141_00610 S100141_00610 S100141_00610 529134 529904 + hypothetical protein gene gene609 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00610 S100141_00611 S100141_00611 arcC arcC 529910 530842 + Carbamate kinase Arginine metabolism%3B ATP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the carbamate kinase family%3B KEGG: bli:BL01102 carbamate kinase gene gene610 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00611 S100141_00612 S100141_00612 S100141_00612 531058 532311 + putative sugar efflux transporter Cell inner membrane%3B Cell membrane%3B Membrane%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites%3B Belongs to the major facilitator superfamily. SotB (TC 2. A. 1. 2) family gene gene611 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00612 S100141_00613 S100141_00613 S100141_00613 532339 532677 + uncharacterized protein Signal. gene gene612 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00613 S100141_00614 S100141_00614 rapG rapG 532980 534080 + Response regulator aspartate phosphatase Hydrolase%3B Protein phosphatase%3B Repeat%3B TPR repeat%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bli:BL01363 response regulator aspartate phosphatase G%3B Acting on ester bonds gene gene613 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00614 S100141_00615 S100141_00615 S100141_00615 534080 534196 + hypothetical protein gene gene614 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00615 S100141_00616 S100141_00616 S100141_00616 535052 535579 - hypothetical protein gene gene615 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00616 S100141_00617 S100141_00617 S100141_00617 535685 536179 + hypothetical protein gene gene616 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00617 S100141_00618 S100141_00618 S100141_00618 536437 537474 + HTH-type transcriptional regulator EbgR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Repressor for beta galactosidase alpha and beta subunits (ebgA and ebgC). Binds lactose as an inducer. Contains 1 HTH lacI-type DNA-binding domain gene gene617 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00618 S100141_00619 S100141_00619 S100141_00619 537588 538841 + Putative binding protein MsmE Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B Probably part of an ABC transporter complex. Belongs to the bacterial solute-binding protein 1 family gene gene618 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00619 S100141_00620 S100141_00620 S100141_00620 538881 539801 + Putative ABC transporter permease protein AmyD Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably part of an ABC transporter complex. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene619 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00620 S100141_00621 S100141_00621 S100141_00621 539802 540632 + Putative ABC transporter permease protein AmyC Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably part of an ABC transporter complex. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene620 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00621 S100141_00622 S100141_00622 melA melA 540663 541961 + Alpha-galactosidase Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Manganese%3B Metal-binding%3B NAD%3B Belongs to the glycosyl hydrolase 4 family%3B KEGG: dsh:Dshi_1245 alpha-galactosidase gene gene621 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00622 S100141_00623 S100141_00623 S100141_00623 541986 543140 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the AbrB family gene gene622 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00623 S100141_00624 S100141_00624 S100141_00624 543351 543584 + Protein CotJA gene gene623 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00624 S100141_00625 S100141_00625 S100141_00625 543590 543853 + Protein CotJB gene gene624 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00625 S100141_00626 S100141_00626 S100141_00626 543875 544444 + Protein CotJC The cotJ operon proteins affect spore coat composition. They are either required for the normal formation of the inner layers of the coat or are themselves structural components of the coat. Belongs to the manganese catalase family gene gene625 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00626 S100141_00627 S100141_00627 S100141_00627 544488 546107 - Long-chain-fatty-acid--CoA ligase ATP-binding%3B Cholesterol metabolism%3B Ligase%3B Lipid metabolism%3B Nucleotide-binding%3B Steroid metabolism%3B Sterol metabolism%3B Involved in the catabolism of the rings C and D of cholesterol. Catalyzes the ATP-dependent CoA thioesterification of 3aalpha-H-4alpha(3'-propanoate)-7abeta-methylhexahydro-1%2C5- indanedione (HIP)%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bli:BL01325 long-chain acyl-CoA synthetase gene gene626 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00627 S100141_00628 S100141_00628 S100141_00628 546159 546713 - putative MFS-type transporter YhjO Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene627 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00628 S100141_00629 S100141_00629 S100141_00629 546949 548190 - hypothetical protein gene gene628 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00629 S100141_00630 S100141_00630 S100141_00630 548273 549640 - Heme sensor protein HssS ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Virulence%3B Member of the two-component regulatory system HssS/HssR involved in intracellular heme homeostasis and tempering of staphylococcal virulence. HssS functions as a heme sensor histidine kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to an aspartate residue of HssR. HssR/HssS activates the expression of hrtAB%2C an efflux pump%2C in response to extracellular heme%2C hemin%2C hemoglobin or blood (By similarity)%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: bli:BL01322 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene629 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00630 S100141_00631 S100141_00631 S100141_00631 549637 550311 - Transcriptional regulatory protein WalR Activator%3B Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system WalK/WalR that regulates genes involved in autolysis%2C biofilm formation and cell wall metabolism%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene630 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00631 S100141_00632 S100141_00632 S100141_00632 550401 550841 - uncharacterized protein gene gene631 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00632 S100141_00633 S100141_00633 S100141_00633 551045 551839 + Putative ABC transporter substrate-binding lipoprotein YvgL Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Belongs to the bacterial solute-binding protein 1 family gene gene632 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00633 S100141_00634 S100141_00634 S100141_00634 551848 552504 + Putative molybdenum transport system permease protein YvgM Cell membrane%3B Membrane%3B Molybdenum%3B Transmembrane%3B Transmembrane helix%3B Transport%3B could be part of the binding-protein-dependent transport system for molybdenu%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene633 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00634 S100141_00635 S100141_00635 addB addB 552614 556114 + ATP-dependent helicase/deoxyribonuclease subunit 4Fe-4S%3B ATP-binding%3B DNA damage%3B DNA repair%3B Exonuclease%3B Hydrolase%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Nuclease%3B Nucleotide-binding%3B The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent%2C dual-direction single-stranded exonuclease%3B this subunit has 5' -> 3' nuclease activity%3B Belongs to the helicase family. AddB/RexB type 1 subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: bli:BL01351 ATP-dependent helicase/nuclease subunit B%3B Acting on ester bonds gene gene634 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00635 S100141_00636 S100141_00636 addA addA 556101 559793 + ATP-dependent helicase/nuclease subunit ATP-binding%3B DNA damage%3B DNA repair%3B DNA-binding%3B Exonuclease%3B Helicase%3B Hydrolase%3B Nuclease%3B Nucleotide-binding%3B The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent%2C dual-direction single-stranded exonuclease%3B this subunit has the helicase and 3' -> 5' nuclease activities%3B Belongs to the helicase family. AddA subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: bli:BL01350 ATP-dependent helicase/nuclease subunit A%3B Acting on ester bonds gene gene635 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00636 S100141_00637 S100141_00637 S100141_00637 559858 561039 + Nuclease SbcCD subunit Coiled coil%3B DNA recombination%3B Exonuclease%3B Hydrolase%3B Nuclease%3B SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity (By similarity)%3B Belongs to the SbcD family%3B overlaps another CDS with the same product name gene gene636 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00637 S100141_00638 S100141_00638 S100141_00638 561036 564428 + Nuclease SbcCD subunit ATP-binding%3B Coiled coil%3B DNA recombination%3B DNA replication%3B Endonuclease%3B Exonuclease%3B Hydrolase%3B Nuclease%3B Nucleotide-binding%3B SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity (By similarity)%3B Belongs to the SMC family. SbcC subfamily%3B overlaps another CDS with the same product name gene gene637 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00638 S100141_00639 S100141_00639 S100141_00639 564472 564690 - putative spore germination protein GerPF Germination%3B Sporulation%3B Required for the formation of functionally normal spores. Could be involved in the establishment of normal spore coat structure and/or permeability%2C which allows the access of germinants to their receptor. Belongs to the GerPA/GerPF family gene gene638 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00639 S100141_00640 S100141_00640 S100141_00640 564746 565132 - putative spore germination protein GerPE Germination%3B Sporulation. gene gene639 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00640 S100141_00641 S100141_00641 S100141_00641 565129 565308 - putative spore germination protein GerPD Germination%3B Sporulation. gene gene640 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00641 S100141_00642 S100141_00642 S100141_00642 565305 565910 - putative spore germination protein GerPC Germination%3B Sporulation. gene gene641 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00642 S100141_00643 S100141_00643 S100141_00643 565931 566173 - putative spore germination protein GerPB Germination%3B Sporulation. gene gene642 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00643 S100141_00644 S100141_00644 S100141_00644 566185 566406 - putative spore germination protein GerPA Germination%3B Sporulation%3B Required for the formation of functionally normal spores. Could be involved in the establishment of normal spore coat structure and/or permeability%2C which allows the access of germinants to their receptor. Belongs to the GerPA/GerPF family gene gene643 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00644 S100141_00645 S100141_00645 S100141_00645 566588 566881 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene644 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00645 S100141_00646 S100141_00646 S100141_00646 566963 567145 - Aspartyl-phosphate phosphatase YisI Hydrolase%3B Sporulation%3B Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation%3B Belongs to the spo0E family gene gene645 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00646 S100141_00647 S100141_00647 S100141_00647 567309 568382 - Inner spore coat protein Sporulation%3B Involved in the assembly of several proteins in the inner and outer layer of the spore coat. Stabilizes CotC and CotU in the mother cell compartment of sporulating cells and promotes the assembly of both early and late forms of CotC-related polypeptides on the spore surface%3B Belongs to the CotH family gene gene646 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00647 S100141_00648 S100141_00648 S100141_00648 568548 569054 + hypothetical protein gene gene647 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00648 S100141_00649 S100141_00649 S100141_00649 569207 570112 + Acylpyruvate hydrolase Metal-binding%3B Belongs to the FAH family%3B KEGG: fal:FRAAL6170 acylpyruvate hydrolase gene gene648 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00649 S100141_00650 S100141_00650 S100141_00650 570128 570238 + hypothetical protein gene gene649 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00650 S100141_00651 S100141_00651 rsgA rsgA 570382 571434 + Putative ribosome bioproteinis GTPase RsgA GTP-binding%3B Hydrolase%3B Metal-binding%3B Nucleotide-binding%3B Plasmid%3B Zinc%3B May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover%3B Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily%3B Contains 1 CP-type G (guanine nucleotide-binding) domain%3B KEGG: bli:BL01344 ribosome biogenesis GTPase%3B In phosphorus-containing anhydrides gene gene650 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00651 S100141_00652 S100141_00652 S100141_00652 571454 571924 + UPF0344 protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0344 family gene gene651 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00652 S100141_00653 S100141_00653 S100141_00653 571964 572530 - uncharacterized protein gene gene652 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00653 S100141_00654 S100141_00654 asnB asnB 572695 574536 + Asparagine synthase (glutamine-hydrolyzing) Amino-acid biosynthesis%3B Asparagine biosynthesis%3B ATP-binding%3B Glutamine amidotransferase%3B Ligase%3B Nucleotide-binding%3B Sporulation%3B Asparagine synthetase involved in sporulation. Belongs to the asparagine synthetase family%3B Contains 1 glutamine amidotransferase type-2 domain%3B KEGG: ppw:PputW619_2683 asparagine synthase (glutamine-hydrolysing) gene gene653 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00654 S100141_00655 S100141_00655 S100141_00655 574668 575498 - Putative ammonium transporter Ammonia transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the ammonia transporter channel (TC 1. A. 11. 2) family gene gene654 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00655 S100141_00656 S100141_00656 S100141_00656 575565 576047 - Putative ammonium transporter Ammonia transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the ammonia transporter channel (TC 1. A. 11. 2) family gene gene655 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00656 S100141_00657 S100141_00657 S100141_00657 576105 576446 - Nitrogen regulatory protein P-II Nucleotide-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B In nitrogen-limiting conditions%2C when the ratio of Gln to 2-ketoglutarate decreases%2C P-II is uridylylated to P-II-UMP. P- II-UMP allows the deadenylation of glutamine synthetase (GS)%2C thus activating the enzyme. Conversely%2C in nitrogen excess P-II is deuridylated and promotes the adenylation of GS. P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate%2C the transcriptional activator of glnA. When P-II is uridylylated to P- II-UMP%2C these events are reversed (By similarity)%3B Belongs to the P(II) protein family gene gene656 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00657 S100141_00658 S100141_00658 S100141_00658 576649 577989 - putative transporter YisQ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the multi antimicrobial extrusion (MATE) (TC 2. A. 66. 1) family gene gene657 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00658 S100141_00659 S100141_00659 S100141_00659 578111 578974 + putative HTH-type transcriptional regulator YisR DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH araC/xylS-type DNA-binding domain gene gene658 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00659 S100141_00660 S100141_00660 S100141_00660 579003 579560 + Putative ribosomal N-acetyltransferase YdaF Acyltransferase%3B Transferase%3B Putative N-acetyltransferase. May act on ribosomal proteins (Potential)%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK1895 null%3B Transferring groups other than amino-acyl groups gene gene659 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00660 S100141_00661 S100141_00661 S100141_00661 579617 580660 + HTH-type transcriptional regulator DegA Activator%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Involved in the control of degradation of B. subtilis amidophosphoribosyltransferase (purF). Probably activates the gene for a degradative protease. Contains 1 HTH lacI-type DNA-binding domain gene gene660 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00661 S100141_00662 S100141_00662 iolX iolX 580828 581388 + Scyllo-inositol 2-dehydrogenase (NAD(+)) NAD%3B Oxidoreductase%3B Catalyzes the NAD(+)-dependent oxidation of scyllo- inositol to 2%2C4%2C6/3%2C5-pentahydroxycyclohexanone (scyllo-inosose)%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: bli:BL01338 scyllo-inositol 2-dehydrogenase (NAD+)%3B overlaps another CDS with the same product name gene gene661 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00662 S100141_00663 S100141_00663 S100141_00663 581388 581855 + Scyllo-inositol 2-dehydrogenase (NAD(+)) NAD%3B Oxidoreductase%3B Catalyzes the NAD(+)-dependent oxidation of scyllo- inositol to 2%2C4%2C6/3%2C5-pentahydroxycyclohexanone (scyllo-inosose)%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: bli:BL01338 scyllo-inositol 2-dehydrogenase (NAD+)%3B overlaps another CDS with the same product name gene gene662 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00663 S100141_00664 S100141_00664 S100141_00664 581947 582732 + putative HTH-type transcriptional regulator YisV Aminotransferase%3B DNA-binding%3B Pyridoxal phosphate%3B Transcription%3B Transcription regulation%3B Transferase%3B In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene663 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00664 S100141_00665 S100141_00665 ectB ectB 583019 584365 + Diaminobutyrate--2-oxoglutarate transaminase Aminotransferase%3B Pyridoxal phosphate%3B Transferase%3B Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bli:BL01336 diaminobutyrate-2-oxoglutarate transaminase gene gene664 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00665 S100141_00666 S100141_00666 S100141_00666 584349 585860 + Diaminobutyrate decarboxylase Decarboxylase%3B Lyase%3B Pyridoxal phosphate%3B Belongs to the group II decarboxylase family%3B KEGG: bli:BL01335 L-2%2C4-diaminobutyrate decarboxylase gene gene665 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00666 S100141_00667 S100141_00667 iucA iucA 585857 587623 + N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase Plasmid%3B Belongs to the IucA family%3B KEGG: vcy:IX92_17045 N2-citryl-N6-acetyl-N6-hydroxylysine synthase gene gene666 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00667 S100141_00668 S100141_00668 iucB iucB 587620 588174 + N(6)-hydroxylysine O-acetyltransferase Plasmid%3B Belongs to the IucB family%3B KEGG: bba:Bd1575 acetyl CoA:N6-hydroxylysine acetyl transferase gene gene667 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00668 S100141_00669 S100141_00669 iucD iucD 588149 589492 + L-lysine N(6)-monooxygenase (NADPH) FAD%3B Flavoprotein%3B NADP%3B Oxidoreductase%3B Plasmid%3B Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family%3B KEGG: bpu:BPUM_1023 lysine N6-hydroxylase gene gene668 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00669 S100141_00670 S100141_00670 iucC iucC 589509 591323 + Aerobactin synthase Plasmid%3B Belongs to the IucC family%3B KEGG: pam:PANA_0352 aerobactin synthase gene gene669 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00670 S100141_00671 S100141_00671 S100141_00671 591366 591806 - putative N-acetyltransferase YitI Acyltransferase%3B Transferase%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bba:Bd0335 null%3B Transferring groups other than amino-acyl groups gene gene670 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00671 S100141_00672 S100141_00672 fabG fabG 591971 592804 - 3-oxoacyl-[acyl-carrier-protein] reductase Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B NADP%3B Oxidoreductase%3B Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products%2C the first reductive step in the elongation cycle of fatty acid biosynthesis%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: sehc:A35E_00575 3-oxoacyl-(acyl-carrier protein) reductase gene gene671 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00672 S100141_00673 S100141_00673 S100141_00673 592916 593878 + putative HTH-type transcriptional regulator YobV Cytoplasm%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH deoR-type DNA-binding domain gene gene672 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00673 S100141_00674 S100141_00674 metH metH 593953 597369 - Methionine synthase Amino-acid biosynthesis%3B Cobalamin%3B Cobalt%3B Metal-binding%3B Methionine biosynthesis%3B Methyltransferase%3B Repeat%3B S-adenosyl-L-methionine%3B Transferase%3B Zinc%3B Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine%2C yielding enzyme-bound cob(I)alamin and methionine. Subsequently%2C remethylates the cofactor using methyltetrahydrofolate (By similarity)%3B Belongs to the vitamin-B12 dependent methionine synthase family%3B Contains 1 AdoMet activation domain%3B Contains 1 B12-binding domain%3B Contains 1 B12-binding N-terminal domain%3B Contains 1 Hcy-binding domain%3B Contains 1 pterin-binding domain%3B KEGG: bli:BL01308 5-methyltetrahydrofolate--homocysteine methyltransferase gene gene673 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00674 S100141_00675 S100141_00675 mmuM mmuM 597362 599191 - Homocysteine S-methyltransferase Amino-acid biosynthesis%3B FAD%3B Flavoprotein%3B Metal-binding%3B Methionine biosynthesis%3B Methyltransferase%3B NAD%3B NADP%3B Oxidoreductase%3B S-adenosyl-L-methionine%3B Transferase%3B Zinc%3B In the C-terminal sectio%3B belongs to the methylenetetrahydrofolate reductase family%3B Contains 1 Hcy-binding domain%3B KEGG: bli:BL01307 homocysteine S-methyltransferase gene gene674 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00675 S100141_00676 S100141_00676 S100141_00676 599461 599952 - UPF0234 protein Belongs to the UPF0234 family gene gene675 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00676 S100141_00677 S100141_00677 S100141_00677 600116 600964 + uncharacterized protein Contains 1 S1 motif domain gene gene676 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00677 S100141_00678 S100141_00678 S100141_00678 601003 601125 - hypothetical protein gene gene677 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00678 S100141_00679 S100141_00679 S100141_00679 601278 601484 + hypothetical protein gene gene678 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00679 S100141_00680 S100141_00680 S100141_00680 601525 602385 - DegV domain-containing protein YitS Lipid-binding%3B May bind long-chain fatty acids%2C such as palmitate%2C and may play a role in lipid transport or fatty acid metabolism%3B Contains 1 DegV domain gene gene679 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00680 S100141_00681 S100141_00681 S100141_00681 602549 603391 + UPF0750 membrane protein YitT Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0750 family gene gene680 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00681 S100141_00682 S100141_00682 S100141_00682 603407 603859 + Intracellular proteinase inhibitor Cytoplasm%3B Protease inhibitor%3B Serine protease inhibitor. gene gene681 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00682 S100141_00683 S100141_00683 S100141_00683 603959 604939 - GMP reductase NADP%3B Oxidoreductase%3B Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase%2C nucleoside and nucleotide derivatives of G to A nucleotides%2C and in maintaining the intracellular balance of A and G nucleotides%3B Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily%3B KEGG: bsu:BSU32130 GMP reductase gene gene682 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00683 S100141_00684 S100141_00684 S100141_00684 605118 605306 - uncharacterized protein gene gene683 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00684 S100141_00685 S100141_00685 S100141_00685 605545 606357 - Putative phosphatase YitU Hydrolase%3B Magnesium%3B Metal-binding%3B Belongs to the HAD-like hydrolase superfamily. Cof family gene gene684 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00685 S100141_00686 S100141_00686 S100141_00686 606480 607247 + Esterase Hydrolase%3B Displays esterase activity toward palmitoyl-CoA and pNP- butyrate gene gene685 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00686 S100141_00687 S100141_00687 S100141_00687 607310 607618 + MIP18 family protein YitW Belongs to the MIP18 family gene gene686 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00687 S100141_00688 S100141_00688 argC argC 607960 608997 + N-acetyl-gamma-glutamyl-phosphate reductase Amino-acid biosynthesis%3B Arginine biosynthesis%3B Cytoplasm%3B NADP%3B Oxidoreductase%3B Belongs to the NAGSA dehydrogenase family. Type 1 subfamily%3B KEGG: hhc:M911_03575 N-acetyl-gamma-glutamyl-phosphate reductase gene gene687 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00688 S100141_00689 S100141_00689 argJ argJ 609017 610237 + Glutamate N-acetyltransferase Acyltransferase%3B Amino-acid biosynthesis%3B Arginine biosynthesis%3B Autocatalytic cleavage%3B Cytoplasm%3B Multifunctional enzyme%3B Transferase%3B Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor%2C and of ornithine by transacetylation between N(2)-acetylornithine and glutamate%3B Belongs to the ArgJ family%3B KEGG: bli:BL03242 glutamate N-acetyltransferase / amino-acid N-acetyltransferase gene gene688 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00689 S100141_00690 S100141_00690 argB argB 610252 611028 + Acetylglutamate kinase Amino-acid biosynthesis%3B Arginine biosynthesis%3B ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the acetylglutamate kinase family%3B KEGG: bsu:BSU11210 acetylglutamate kinase gene gene689 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00690 S100141_00691 S100141_00691 argD argD 611025 612182 + Acetylornithine transaminase Amino-acid biosynthesis%3B Aminotransferase%3B Arginine biosynthesis%3B Cytoplasm%3B Pyridoxal phosphate%3B Transferase%3B Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily%3B KEGG: bli:BL03244 acetylornithine aminotransferase gene gene690 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00691 S100141_00692 S100141_00692 carA carA 612249 613313 + Carbamoyl-phosphate synthase (glutamine-hydrolyzing) Amino-acid biosynthesis%3B Arginine biosynthesis%3B ATP-binding%3B Glutamine amidotransferase%3B Ligase%3B Nucleotide-binding%3B Belongs to the CarA family%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: bba:Bd0856 carbamoyl-phosphate synthase small subunit%3B overlaps another CDS with the same product name gene gene691 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00692 S100141_00693 S100141_00693 carB carB 613306 616395 + Carbamoyl-phosphate synthase (glutamine-hydrolyzing) Amino-acid biosynthesis%3B Arginine biosynthesis%3B ATP-binding%3B Ligase%3B Magnesium%3B Manganese%3B Metal-binding%3B Nucleotide-binding%3B Pyrimidine biosynthesis%3B Repeat%3B Belongs to the CarB family%3B Contains 2 ATP-grasp domains%3B KEGG: dav:DESACE_04490 carbamoyl-phosphate synthase large subunit%3B overlaps another CDS with the same product name gene gene692 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00693 S100141_00694 S100141_00694 argF argF 616383 617333 + Ornithine carbamoyltransferase Amino-acid biosynthesis%3B Arginine biosynthesis%3B Cytoplasm%3B Transferase%3B Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline%3B Belongs to the ATCase/OTCase family%3B KEGG: bli:BL03247 ornithine carbamoyltransferase gene gene693 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00694 S100141_00695 S100141_00695 S100141_00695 617367 618179 - Undecaprenyl-diphosphate phosphatase Antibiotic resistance%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Membrane%3B Peptidoglycan synthesis%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin%3B Belongs to the UppP family%3B KEGG: nma:NMA2077 undecaprenyl-diphosphatase gene gene694 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00695 S100141_00696 S100141_00696 S100141_00696 618361 618540 + uncharacterized protein gene gene695 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00696 S100141_00697 S100141_00697 S100141_00697 618612 618806 - putative membrane protein YjzD Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene696 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00697 S100141_00698 S100141_00698 S100141_00698 619038 619772 + uncharacterized protein gene gene697 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00698 S100141_00699 S100141_00699 S100141_00699 619859 620434 + uncharacterized protein gene gene698 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00699 S100141_00700 S100141_00700 S100141_00700 620521 621474 + Transcriptional activator protein med Activator%3B Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transcription%3B Transcription regulation%3B Positive activator of the comK gene. Belongs to the BMP lipoprotein family gene gene699 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00700 S100141_00701 S100141_00701 S100141_00701 621485 621670 + ComG operon repressor Competence%3B Repressor%3B Transcription%3B Transcription regulation%3B Negatively regulates the transcription of the comG operon gene gene700 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00701 S100141_00702 S100141_00702 S100141_00702 621722 621961 - uncharacterized protein gene gene701 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00702 S100141_00703 S100141_00703 S100141_00703 622131 623069 + Beta-ketoacyl-[acyl-carrier-protein] synthase III Acyltransferase%3B Cytoplasm%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Multifunctional enzyme%3B Transferase%3B Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Has some substrate specificity for branched chain acyl-CoA%2C determining the biosynthesis of branched-chain of fatty acids instead of straight-chain%3B Belongs to the FabH family%3B KEGG: bsu:BSU11330 3-oxoacyl-(acyl-carrier-protein) synthase III gene gene702 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00703 S100141_00704 S100141_00704 fabF fabF 623091 624329 + Beta-ketoacyl-[acyl-carrier-protein] synthase II Acyltransferase%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Transferase%3B Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthesis (By similarity)%3B Belongs to the beta-ketoacyl-ACP synthases family%3B KEGG: spe:Spro_1749 3-oxoacyl-(acyl-carrier-protein) synthase II gene gene703 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00704 S100141_00705 S100141_00705 S100141_00705 624417 625205 + uncharacterized protein gene gene704 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00705 S100141_00706 S100141_00706 S100141_00706 625397 626371 + Oligopeptide transport ATP-binding protein AppD ATP-binding%3B Cell membrane%3B Competence%3B Membrane%3B Nucleotide-binding%3B Peptide transport%3B Protein transport%3B Sporulation%3B Transport%3B This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence%2C though%2C unlike OPP%2C is incapable of transporting tripeptides. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene705 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00706 S100141_00707 S100141_00707 S100141_00707 626375 627397 + Oligopeptide transport ATP-binding protein AppF ATP-binding%3B Cell membrane%3B Competence%3B Membrane%3B Nucleotide-binding%3B Peptide transport%3B Protein transport%3B Sporulation%3B Transport%3B This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence%2C though%2C unlike OPP%2C is incapable of transporting tripeptides. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene706 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00707 S100141_00708 S100141_00708 S100141_00708 627510 629141 + Oligopeptide-binding protein AppA Cell membrane%3B Competence%3B Lipoprotein%3B Membrane%3B Palmitate%3B Peptide transport%3B Protein transport%3B Signal%3B Sporulation%3B Transport%3B This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence. AppA can bind and transport tetra- and pentapeptides but not tripeptides. Belongs to the bacterial solute-binding protein 5 family gene gene707 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00708 S100141_00709 S100141_00709 S100141_00709 629247 630167 + Oligopeptide transport system permease protein AppB Cell membrane%3B Competence%3B Membrane%3B Peptide transport%3B Protein transport%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence%2C though%2C unlike OPP%2C is incapable of transporting tripeptides. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene708 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00709 S100141_00710 S100141_00710 S100141_00710 630186 631100 + Oligopeptide transport system permease protein AppC Cell membrane%3B Competence%3B Membrane%3B Peptide transport%3B Protein transport%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence%2C though%2C unlike OPP%2C is incapable of transporting tripeptides. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene709 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00710 S100141_00711 S100141_00711 S100141_00711 631620 632972 + hypothetical protein gene gene710 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00711 S100141_00712 S100141_00712 S100141_00712 632965 633522 + Phosphopantothenoylcysteine decarboxylase Flavoprotein%3B FMN%3B Lyase%3B Plasmid%3B Catalyzes the removal of two reducing equivalents (oxidative decarboxylation) from the cysteine residue of the C- terminal meso-lanthionine of epidermin to form a --C%3D%3DC-- double bond. Belongs to the HFCD (homooligomeric flavin containing Cys decarboxylase) superfamily%3B KEGG: sul:SYO3AOP1_1251 phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase gene gene711 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00712 S100141_00713 S100141_00713 S100141_00713 633555 634820 + hypothetical protein gene gene712 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00713 S100141_00714 S100141_00714 S100141_00714 635035 635787 + UPF0736 protein Belongs to the UPF0736 family gene gene713 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00714 S100141_00715 S100141_00715 warS warS 636031 637023 - Tryptophan--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: bex:A11Q_1236 tryptophanyl-tRNA synthetase gene gene714 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00715 S100141_00716 S100141_00716 S100141_00716 637761 639386 + Oligopeptide-binding protein OppA Cell membrane%3B Competence%3B Lipoprotein%3B Membrane%3B Palmitate%3B Peptide transport%3B Phosphoprotein%3B Protein transport%3B Signal%3B Sporulation%3B Transport%3B This protein is a component of the oligopeptide permease%2C a binding protein-dependent transport system%2C It binds peptides up to five amino acids long with high affinity. Also required for sporulation and competence. Belongs to the bacterial solute-binding protein 5 family gene gene715 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00716 S100141_00717 S100141_00717 S100141_00717 639482 640417 + Dipeptide transport system permease protein DppB Cell membrane%3B Membrane%3B Peptide transport%3B Protein transport%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system for dipeptide%3B probably responsible for the translocation of the substrate across the membrane. Is expressed to facilitate adaptation to nutrient deficiency conditions. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene716 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00717 S100141_00718 S100141_00718 S100141_00718 640422 641339 + Oligopeptide transport system permease protein OppC Cell membrane%3B Competence%3B Membrane%3B Peptide transport%3B Protein transport%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system for oligopeptide%3B probably responsible for the translocation of the substrate across the membrane. Also required for sporulation and competence. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene717 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00718 S100141_00719 S100141_00719 S100141_00719 641353 642420 + Glutathione import ATP-binding protein GsiA ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Repeat%3B Transport%3B Part of the ABC transporter complex GsiABCD involved in glutathione import. Responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily. Glutathione importer (TC 3. A. 1. 5. 11) family%3B Contains 2 ABC transporter domains gene gene718 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00719 S100141_00720 S100141_00720 S100141_00720 642422 643345 + Oligopeptide transport ATP-binding protein AmiF ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Peptide transport%3B Protein transport%3B Transport%3B Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene719 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00720 S100141_00721 S100141_00721 S100141_00721 643576 644154 + Putative acetyltransferase YjbC Acyltransferase%3B Cytoplasm%3B Transferase%3B Contains 1 N-acetyltransferase domain gene gene720 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00721 S100141_00722 S100141_00722 S100141_00722 644332 644727 + Regulatory protein Spx Cytoplasm%3B Disulfide bond%3B Redox-active center%3B Transcription%3B Transcription regulation%3B Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis%2C during periods of extreme stress%3B Belongs to the ArsC family. Spx subfamily gene gene721 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00722 S100141_00723 S100141_00723 S100141_00723 644950 645612 - putative membrane protein YjbE Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the TerC family gene gene722 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00723 S100141_00724 S100141_00724 S100141_00724 645898 646536 + Adapter protein MecA Competence%3B Sporulation%3B Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed%2C inhibits sporulation. Also involved in Spx degradation by ClpC (By similarity)%3B Belongs to the MecA family gene gene723 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00724 S100141_00725 S100141_00725 S100141_00725 646662 647711 + UPF0065 protein YflP Signal%3B Belongs to the UPF0065 (bug) family gene gene724 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00725 S100141_00726 S100141_00726 S100141_00726 647814 648269 + hypothetical protein gene gene725 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00726 S100141_00727 S100141_00727 S100141_00727 648292 649797 + putative 52.8 kDa protein in TAR-I ttuC' 3'region Plasmid. gene gene726 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00727 S100141_00728 S100141_00728 S100141_00728 649817 650533 - Transcriptional regulatory protein CitT Activator%3B Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system CitT/CitS. Regulates the expression of the citM-yflN operon. Phosphorylated CitT binds to the citM promoter to activate the transcription of the citM-yflN operon%3B Contains 1 response regulatory domain gene gene727 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00728 S100141_00729 S100141_00729 S100141_00729 650556 650903 - Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system CitT/CitS. Regulates the expression of the citM-yflN operon. Functions probably as a membrane-associated protein kinase that phosphorylates CitT in response to environmental citrate or Mg(2+)-citrate complex%3B Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bli:BL03342 two-component system%2C CitB family%2C sensor kinase%3B overlaps another CDS with the same product name gene gene728 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00729 S100141_00730 S100141_00730 S100141_00730 650900 652150 - Histidine kinase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system DcuR/DcuS. Involved in the C4-dicarboxylate-stimulated regulation of the genes encoding the anaerobic fumarate respiratory system (frdABC%3B nuoA%3B dcu%3B dcu%3B sdhCDA%3B etc.). Weakly regulates the aerobic C4-dicarboxylate transporter dctA. Activates DcuR by phosphorylation (By similarity)%3B Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bli:BL03342 two-component system%2C CitB family%2C sensor kinase%3B overlaps another CDS with the same product name gene gene729 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00730 S100141_00731 S100141_00731 S100141_00731 652268 653416 + Putative competence protein CoiA Competence%3B Cytoplasm%3B Required for optimal transformation gene gene730 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00731 S100141_00732 S100141_00732 pepF pepF 653413 655458 + Oligoendopeptidase F like protein Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Zinc%3B Belongs to the peptidase M3B family%3B KEGG: bli:BL03337 oligoendopeptidase F%3B Metalloendopeptidases gene gene731 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00732 S100141_00733 S100141_00733 S100141_00733 655515 655682 - putative membrane protein YizD Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene732 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00733 S100141_00734 S100141_00734 S100141_00734 656094 656996 - UPF0413 protein Belongs to the UPF0413 family gene gene733 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00734 S100141_00735 S100141_00735 S100141_00735 656993 657391 - Group 2 truncated hemoglobin YjbI Heme%3B Iron%3B Metal-binding%3B Transport%3B Hemoglobin-like protein that exhibits a low peroxidase activity. Its very high oxygen affinity may rule out the possibility that it is involved in oxygen transport%3B Belongs to the truncated hemoglobin family. Group II subfamily gene gene734 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00735 S100141_00736 S100141_00736 S100141_00736 657673 658326 - Membrane-bound lytic murein transglycosylase Cell outer membrane%3B Cell wall biogenesis/degradation%3B Lipoprotein%3B Lyase%3B Membrane%3B Palmitate%3B Signal%3B Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division%3B Belongs to the transglycosylase Slt family gene gene735 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00736 S100141_00737 S100141_00737 S100141_00737 658339 658911 - Glutathione transferase Hydrolase%3B Contains 1 CYTH domain%3B KEGG: sar:SAR0971 glutathione S-transferase gene gene736 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00737 S100141_00738 S100141_00738 S100141_00738 659042 659407 + UPF0738 protein Belongs to the UPF0738 family gene gene737 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00738 S100141_00739 S100141_00739 S100141_00739 659439 660074 + GTP diphosphokinase ATP-binding%3B GTP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Functions as a (p)ppGpp synthase. In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. YjbM has probably a minor role in stringent response%3B Belongs to the RelA/SpoT family%3B KEGG: bli:BL03338 putative GTP pyrophosphokinase gene gene738 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00739 S100141_00740 S100141_00740 ppnK ppnK 660089 660892 + NAD(+) kinase ATP-binding%3B Cytoplasm%3B Kinase%3B NAD%3B NADP%3B Nucleotide-binding%3B Transferase%3B Involved in the regulation of the intracellular balance of NAD and NADP%2C and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP%3B Belongs to the NAD kinase family%3B KEGG: bli:BL05111 NAD+ kinase gene gene739 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00740 S100141_00741 S100141_00741 S100141_00741 660904 661794 + 23S rRNA pseudouridine(1911/1915/1917) synthase Isomerase%3B Belongs to the pseudouridine synthase RluA family%3B KEGG: bli:BL01010 23S rRNA pseudouridine1911/1915/1917 synthase gene gene740 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00741 S100141_00742 S100141_00742 apaH apaH 661810 662550 - Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) Hydrolase%3B Nickel%3B Asymmetrically hydrolyzes Ap4p to yield AMP and ATP%3B Belongs to the PrpE family%3B KEGG: bli:BL05112 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) gene gene741 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00742 S100141_00743 S100141_00743 S100141_00743 662823 664667 + Putative Na(+)/H(+) antiporter YjbQ Antiport%3B Cell membrane%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probable Na(+)/H(+) antiporter%3B Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2. A. 37) family%3B Contains 1 RCK C-terminal domain%3B Contains 1 RCK N-terminal domain gene gene742 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00743 S100141_00744 S100141_00744 tenA tenA 664919 665620 + Aminopyrimidine aminohydrolase Hydrolase%3B Thiamine biosynthesis%3B Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds%2C a reaction that is part of a thiamine salvage pathway. Thus%2C catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP). To a lesser extent%2C is also able to catalyze the hydrolytic cleavage of thiamin%3B however%2C this thiaminase activity is unlikely to be physiologically relevant. Therefore%2C is involved in the regeneration of the thiamine pyrimidine from thiamine degraded products present in the environment%2C rather than in thiamine degradation%3B Belongs to the TenA family%3B KEGG: bsu:BSU11650 thiaminase (transcriptional activator TenA) gene gene743 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00744 S100141_00745 S100141_00745 tenI tenI 665595 666206 + Thiazole tautomerase Isomerase%3B Thiamine biosynthesis%3B Catalyzes the irreversible aromatization of 2-((2R%2C5Z)- 2-carboxy-4-methylthiazol-5(2H)-ylidene)ethyl phosphate (cThz*-P) to 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate (cThz-P)%2C a step in the biosynthesis of the thiazole phosphate moiety of thiamine. Cannot use cThz* as substrate%2C indicating that the phosphate group is essential. Has no thiamine phosphate synthase activity%2C despite a high sequence similarity with ThiE%3B Belongs to the thiazole tautomerase family%3B KEGG: bsu:BSU11660 thiazole tautomerase (transcriptional regulator TenI) gene gene744 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00745 S100141_00746 S100141_00746 thiO thiO 666163 667299 + Glycine oxidase Cytoplasm%3B FAD%3B Flavoprotein%3B Herbicide resistance%3B Oxidoreductase%3B Thiamine biosynthesis%3B Catalyzes the FAD-dependent oxidative deamination of various amines and D-amino acids to yield the corresponding alpha- keto acids%2C ammonia/amine%2C and hydrogen peroxide. Oxidizes sarcosine (N-methylglycine)%2C N-ethylglycine and glycine. Can also oxidize the herbicide glyphosate (N-phosphonomethylglycine). Displays lower activities on D-alanine%2C D-valine%2C D-proline and D- methionine. Does not act on L-amino acids and other D-amino acids. Is essential for thiamine biosynthesis since the oxidation of glycine catalyzed by ThiO generates the glycine imine intermediate (dehydroglycine) required for the biosynthesis of the thiazole ring of thiamine pyrophosphate%3B Belongs to the DAO family%3B KEGG: bli:BL01590 glycine oxidase gene gene745 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00746 S100141_00747 S100141_00747 S100141_00747 667296 667499 + Sulfur carrier protein ThiS Nucleotide-binding%3B Phosphoprotein%3B Thiamine biosynthesis%3B Is the sulfur donor in the synthesis of the thiazole phosphate moiety of thiamine phosphate%3B Belongs to the sulfur carrier protein ThiS family gene gene746 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00747 S100141_00748 S100141_00748 thiG thiG 667506 668273 + Thiazole synthase Cytoplasm%3B Schiff base%3B Thiamine biosynthesis%3B Transferase%3B Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro%2C sulfur can be provided by H(2)S%3B Belongs to the ThiG family%3B KEGG: enr:H650_16535 thiazole synthase gene gene747 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00748 S100141_00749 S100141_00749 thiF thiF 668270 669280 + Sulfur carrier protein ThiS adenylyltransferase ATP-binding%3B Metal-binding%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Thiamine biosynthesis%3B Transferase%3B Zinc%3B Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein ThiS%3B Belongs to the HesA/MoeB/ThiF family%3B KEGG: bsu:BSU11700 sulfur carrier protein ThiS adenylyltransferase gene gene748 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00749 S100141_00750 S100141_00750 thiD thiD 669305 670123 + Hydroxymethylpyrimidine kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Thiamine biosynthesis%3B Transferase%3B Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP%2C and of HMP to HMP-P. Shows no activity with pyridoxal%2C pyridoxamine or pyridoxine%3B Belongs to the ThiD family%3B KEGG: bsu:BSU11710 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase gene gene749 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00750 S100141_00751 S100141_00751 fabI fabI 670280 671056 + Enoyl-[acyl-carrier-protein] reductase (NADH) Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B NAD%3B NADP%3B Oxidoreductase%3B Stress response%3B Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily%3B KEGG: bli:BL05113 enoyl-(acyl-carrier protein) reductase I gene gene750 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00751 S100141_00752 S100141_00752 S100141_00752 671160 671639 + Spore coat protein Sporulation%3B Has an important morphogenetic role. Involved in the assembly of at least five coat proteins%2C including CotB%2C CotG%2C CotS%2C CotSA and CotW. Required for appearance of a morphologically normal outer coat. To a large degree%2C CotO and CotH act at a late stage of coat assembly from within the outer coat to direct maturation of this structure gene gene751 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00752 S100141_00753 S100141_00753 S100141_00753 671677 672126 - Spore coat protein Y Disulfide bond%3B Sporulation%3B To B. subtilis CotZ gene gene752 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00753 S100141_00754 S100141_00754 S100141_00754 672277 672765 - Spore coat protein Y Disulfide bond%3B Sporulation%3B To B. subtilis CotZ gene gene753 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00754 S100141_00755 S100141_00755 S100141_00755 672897 673409 - Spore coat protein X Sporulation. gene gene754 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00755 S100141_00756 S100141_00756 S100141_00756 673480 673878 - Spore coat protein Sporulation. gene gene755 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00756 S100141_00757 S100141_00757 S100141_00757 673927 674313 - Spore coat protein Sporulation. gene gene756 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00757 S100141_00758 S100141_00758 S100141_00758 674460 674816 + Sporulation protein YjcA Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Involved in sporulation%3B Belongs to the UPF0713 family gene gene757 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00758 S100141_00759 S100141_00759 S100141_00759 675103 675312 + hypothetical protein gene gene758 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00759 S100141_00760 S100141_00760 S100141_00760 675392 675523 + UPF0752 sporulation protein YjcZ Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0752 family gene gene759 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00760 S100141_00761 S100141_00761 S100141_00761 675653 675910 + Sporulation-specific transcription factor SpoVIF Cytoplasm%3B Sporulation%3B Transcription%3B Transcription regulation%3B Transcription factor involved in spore coat assembly and spore resistance. Regulates the transcription of at least cgeA%2C cotG and cotS gene gene760 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00761 S100141_00762 S100141_00762 uvrD uvrD 675949 678231 - DNA helicase ATP-binding%3B Cytoplasm%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B May be involved in the generation of recombinogenic substrates for the subsequent action of RecA. Belongs to the helicase family. UvrD subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: bsr:I33_1319 DNA helicase II / ATP-dependent DNA helicase PcrA gene gene761 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00762 S100141_00763 S100141_00763 S100141_00763 678353 678610 + uncharacterized protein gene gene762 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00763 S100141_00764 S100141_00764 phoA phoA 678650 679237 - Alkaline phosphatase Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the DedA family%3B KEGG: oih:OB2407 alkaline phosphatase gene gene763 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00764 S100141_00765 S100141_00765 S100141_00765 679333 680319 - UDP-arabinose 4-epimerase Isomerase%3B NAD%3B Catalyzes the interconversion between UDP-glucose and UDP-galactose%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: psd:DSC_08845 UDP-arabinose 4-epimerase gene gene764 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00765 S100141_00766 S100141_00766 rfbA rfbA 680316 681206 - Glucose-1-phosphate thymidylyltransferase Carbohydrate metabolism%3B Nucleotidyltransferase%3B Transferase%3B Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG)%2C i. e. a glycolipid found in the membrane%2C which is also used as a membrane anchor for lipoteichoic acid (LTA) (By similarity)%3B Belongs to the UDPGP type 2 family%3B KEGG: eco:b2039 glucose-1-phosphate thymidylyltransferase gene gene765 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00766 S100141_00767 S100141_00767 S100141_00767 681229 681624 - putative membrane protein YngA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the GtrA family gene gene766 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00767 S100141_00768 S100141_00768 S100141_00768 681789 682208 - putative N-acetyltransferase YjcF Acyltransferase%3B Transferase%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK1121 null%3B Transferring groups other than amino-acyl groups gene gene767 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00768 S100141_00769 S100141_00769 S100141_00769 682218 682727 - Putative phosphoesterase Hydrolase%3B Belongs to the 2H phosphoesterase superfamily. YjcG family gene gene768 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00769 S100141_00770 S100141_00770 S100141_00770 682792 683514 - uncharacterized protein gene gene769 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00770 S100141_00771 S100141_00771 S100141_00771 684031 684519 - hypothetical protein gene gene770 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00771 S100141_00772 S100141_00772 S100141_00772 684600 685547 - putative HTH-type transcriptional regulator YobV Cytoplasm%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH deoR-type DNA-binding domain gene gene771 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00772 S100141_00773 S100141_00773 metB metB 685856 686980 + Cystathionine gamma-synthase Amino-acid biosynthesis%3B Cytoplasm%3B Methionine biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Catalyzes the formation of L-cystathionine from O- acetyl-L-homoserine and L-cysteine. Can not use O-succinyl-L- homoserine as substrate. Also exhibits O-acetylhomoserine thiolyase activity%2C catalyzing the synthesis of L-homocysteine from O-acetyl-L-homoserine and sulfide%3B Belongs to the trans-sulfuration enzymes family%3B KEGG: bli:BL02660 cystathionine gamma-synthase gene gene772 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00773 S100141_00774 S100141_00774 metC metC 686970 688145 + Cystathionine beta-lyase Amino-acid biosynthesis%3B Cytoplasm%3B Lyase%3B Methionine biosynthesis%3B Pyridoxal phosphate%3B Catalyzes the transformation of cystathionine into homocysteine. Also exhibits cysteine desulfhydrase activity in vitro%2C producing sulfide from cysteine%3B Belongs to the trans-sulfuration enzymes family%3B KEGG: bli:BL02659 cystathionine beta-lyase gene gene773 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00774 S100141_00775 S100141_00775 S100141_00775 688191 689381 - putative membrane protein YjcL Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene774 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00775 S100141_00776 S100141_00776 S100141_00776 689555 690124 + hypothetical protein gene gene775 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00776 S100141_00777 S100141_00777 S100141_00777 690114 690398 + hypothetical protein gene gene776 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00777 S100141_00778 S100141_00778 S100141_00778 690574 691947 + Serine-type D-Ala-D-Ala carboxypeptidase Cytoplasm%3B Hydrolase%3B Acts on short-chain (C4-C6) fatty acid esters and triglycerides%2C including tertiary alcohol esters. Activity on p- nitrophenyl esters is generally higher than on o-nitrophenyl esters. Lacks beta-lactamase activit%3B it hydrolyzes the ester bond of cephalosporin substrates but there is no opening of the beta-lactam ring observed. Belongs to the class-A beta-lactamase family%3B KEGG: sth:STH2021 D-alanyl-D-alanine carboxypeptidase gene gene777 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00778 S100141_00779 S100141_00779 S100141_00779 692252 692644 - Arabinan endo-1%2C5-alpha-L-arabinosidase Calcium%3B Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Metal-binding%3B Secreted%3B Signal%3B Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the internal cleavage of alpha-(1->5)-L-arabinofuranosyl residues of linear 1%2C5-alpha-L-arabinan and of branched sugar beet arabinan. It displays no activity against heavily substituted arabinans or a range of other polysaccharides (larch wood arabinogalactan%2C wheat arabinoxylan and p-nitrophenyl-alpha-L- arabinofuranoside). The enzyme activity is progressively reduced as alpha-(1->5)-chains become shorter or more highly substituted%3B Belongs to the glycosyl hydrolase 43 family%3B KEGG: bsu:BSU28810 arabinan endo-1%2C5-alpha-L-arabinosidase%3B overlaps another CDS with the same product name gene gene778 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00779 S100141_00780 S100141_00780 S100141_00780 692641 693237 - Arabinan endo-1%2C5-alpha-L-arabinosidase Calcium%3B Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Metal-binding%3B Secreted%3B Signal%3B Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the internal cleavage of alpha-(1->5)-L-arabinofuranosyl residues of linear 1%2C5-alpha-L-arabinan and of branched sugar beet arabinan. It displays no activity against heavily substituted arabinans or a range of other polysaccharides (larch wood arabinogalactan%2C wheat arabinoxylan and p-nitrophenyl-alpha-L- arabinofuranoside). The enzyme activity is progressively reduced as alpha-(1->5)-chains become shorter or more highly substituted%3B Belongs to the glycosyl hydrolase 43 family%3B KEGG: bli:BL02653 arabinan endo-1%2C5-alpha-L-arabinosidase%3B overlaps another CDS with the same product name gene gene779 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00780 S100141_00781 S100141_00781 S100141_00781 694115 694187 - tRNA-Val tRNA gene780 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00781 S100141_00782 S100141_00782 S100141_00782 694361 694540 + hypothetical protein gene gene781 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00782 S100141_00783 S100141_00783 S100141_00783 694574 695152 + Maltose O-acetyltransferase Repeat%3B Transferase%3B Acetylates maltose and other sugars. Belongs to the transferase hexapeptide repeat family%3B KEGG: eco:b0459 maltose O-acetyltransferase gene gene782 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00783 S100141_00784 S100141_00784 S100141_00784 695239 695604 - hypothetical protein gene gene783 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00784 S100141_00785 S100141_00785 S100141_00785 695734 696624 - HTH-type transcriptional activator AllS Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Positive regulator essential for the expression of AllD operon. Binds to the AllD promoter (By similarity)%3B Contains 1 HTH lysR-type DNA-binding domain gene gene784 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00785 S100141_00786 S100141_00786 cysJ cysJ 696945 698774 + Assimilatory sulfite reductase (NADPH) Amino-acid biosynthesis%3B Cysteine biosynthesis%3B Electron transport%3B FAD%3B Flavoprotein%3B FMN%3B NADP%3B Oxidoreductase%3B Transport%3B Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component (Probable)%3B Contains 1 FAD-binding FR-type domain%3B Contains 1 flavodoxin-like domain%3B KEGG: bsu:BSU33440 sulfite reductase (NADPH) flavoprotein alpha-component gene gene785 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00786 S100141_00787 S100141_00787 cysI cysI 698802 700520 + Assimilatory sulfite reductase (NADPH) 4Fe-4S%3B Amino-acid biosynthesis%3B Cysteine biosynthesis%3B Heme%3B Iron%3B Iron-sulfur%3B Metal-binding%3B NADP%3B Oxidoreductase%3B Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate%3B Belongs to the nitrite and sulfite reductase 4Fe-4S domain family%3B KEGG: bli:BL01950 sulfite reductase (NADPH) hemoprotein beta-component gene gene786 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00787 S100141_00788 S100141_00788 S100141_00788 700578 701465 - putative HTH-type transcriptional regulator YoaU DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH lysR-type DNA-binding domain gene gene787 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00788 S100141_00789 S100141_00789 S100141_00789 701557 702429 + putative transporter YoaV Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene788 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00789 S100141_00790 S100141_00790 glo1 glo1 702477 702854 + Lactoylglutathione lyase KEGG: msu:MS0597 lactoylglutathione lyase gene gene789 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00790 S100141_00791 S100141_00791 S100141_00791 702898 703446 - uncharacterized protein Signal. gene gene790 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00791 S100141_00792 S100141_00792 cwlJ cwlJ 703899 704633 + N-acetylmuramoyl-L-alanine amidase Cell wall%3B Repeat%3B Secreted%3B Signal%3B Contains 2 LysM repeats%3B KEGG: beo:BEH_04935 N-acetylmuramoyl-L-alanine amidase gene gene791 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00792 S100141_00793 S100141_00793 S100141_00793 704689 706113 - putative MFS-type transporter YcnB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily. EmrB family gene gene792 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00793 S100141_00794 S100141_00794 S100141_00794 706129 706707 - putative HTH-type transcriptional regulator DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH tetR-type DNA-binding domain gene gene793 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00794 S100141_00795 S100141_00795 S100141_00795 706720 707055 - hypothetical protein gene gene794 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00795 S100141_00796 S100141_00796 S100141_00796 707084 707497 - hypothetical protein gene gene795 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00796 S100141_00797 S100141_00797 S100141_00797 707872 708354 - putative antitoxin YezG Coiled coil%3B Probable antitoxin component of a toxin-antitoxin (TA) module. Probably neutralizes the ability to inhibit growth of cognate toxin YeeF. Probably does not have antitoxin activity on other toxins with the LXG toxin domain (Probable) gene gene796 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00797 S100141_00798 S100141_00798 S100141_00798 708358 710082 - Ribonuclease YxiD Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene797 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00798 S100141_00799 S100141_00799 S100141_00799 710099 710404 - Ribonuclease YxiD Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene798 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00799 S100141_00800 S100141_00800 S100141_00800 710625 711272 + UPF0714 protein YndL Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0714 family gene gene799 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00800 S100141_00801 S100141_00801 S100141_00801 711286 711942 - Phage-like element PBSX protein XkdA To B. subtilis YqaB gene gene800 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00801 S100141_00802 S100141_00802 lexA lexA 712131 712484 - Repressor LexA DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Repressor of PBSX. Binds to four sites close to its own gene. Necessary for the maintenance of the lysogenic state%3B Contains 1 HTH cro/C1-type DNA-binding domain%3B KEGG: chy:CHY_1697 repressor LexA gene gene801 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00802 S100141_00803 S100141_00803 S100141_00803 712657 712917 + hypothetical protein gene gene802 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00803 S100141_00804 S100141_00804 S100141_00804 712907 713203 + hypothetical protein gene gene803 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00804 S100141_00805 S100141_00805 S100141_00805 713204 714034 + Phage-like element PBSX protein XkdB DNA-binding%3B To B. subtilis YqaL gene gene804 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00805 S100141_00806 S100141_00806 S100141_00806 714084 714734 + Phage-like element PBSX protein XkdC ATP-binding%3B Nucleotide-binding%3B May function as a transcriptional antiterminator. To B. subtilis YqaM gene gene805 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00806 S100141_00807 S100141_00807 S100141_00807 714734 714904 + hypothetical protein gene gene806 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00807 S100141_00808 S100141_00808 S100141_00808 715005 715346 + Phage-like element PBSX protein XkdD gene gene807 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00808 S100141_00809 S100141_00809 S100141_00809 715343 715546 + Phage-like element PBSX protein XtrA To B. subtilis YqaO gene gene808 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00809 S100141_00810 S100141_00810 S100141_00810 715667 716170 + Positive control factor Activator%3B DNA-binding%3B Transcription%3B Transcription regulation. gene gene809 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00810 S100141_00811 S100141_00811 S100141_00811 716313 717113 + PBSX phage terminase small subunit Viral genome packaging%3B Virus exit from host cell%3B Functions as a terminase. To B. subtilis YqaS and B. subtilis phage SPP1 terminase small subunit gene gene810 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00811 S100141_00812 S100141_00812 S100141_00812 717110 718408 + PBSX phage terminase large subunit Viral genome packaging%3B Virus exit from host cell%3B Functions as a terminase. To B. subtilis YqaT and phage SPP1 terminase large subunit gene gene811 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00812 S100141_00813 S100141_00813 S100141_00813 718412 719926 + uncharacterized protein Belongs to the phage portal family. PBSX subfamily gene gene812 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00813 S100141_00814 S100141_00814 S100141_00814 719934 720782 + Phage-like element PBSX protein XkdF To B. subtilis YqbD gene gene813 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00814 S100141_00815 S100141_00815 S100141_00815 720800 721735 + Phage-like element PBSX protein XkdG Secreted%3B Signal%3B To B. subtilis YqbE gene gene814 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00815 S100141_00816 S100141_00816 S100141_00816 721829 722203 + uncharacterized protein overlaps another CDS with the same product name gene gene815 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00816 S100141_00817 S100141_00817 S100141_00817 722200 722556 + uncharacterized protein To B. subtilis XkdH%3B overlaps another CDS with the same product name gene gene816 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00817 S100141_00818 S100141_00818 S100141_00818 722553 723041 + Phage-like element PBSX protein XkdI To B. subtilis YqbI gene gene817 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00818 S100141_00819 S100141_00819 S100141_00819 723054 723494 + Phage-like element PBSX protein XkdJ To B. subtilis YqbJ gene gene818 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00819 S100141_00820 S100141_00820 S100141_00820 723495 723719 + uncharacterized protein overlaps another CDS with the same product name gene gene819 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00820 S100141_00821 S100141_00821 S100141_00821 723719 725065 + uncharacterized protein Belongs to the myoviridae tail sheath protein family%3B overlaps another CDS with the same product name gene gene820 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00821 S100141_00822 S100141_00822 S100141_00822 725067 725510 + Phage-like element PBSX protein XkdM To B. subtilis YqbM gene gene821 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00822 S100141_00823 S100141_00823 S100141_00823 725693 726142 + uncharacterized protein To B. subtilis XkdN gene gene822 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00823 S100141_00824 S100141_00824 S100141_00824 726325 730107 + Phage-like element PBSX protein XkdO To B. subtilis YqbO gene gene823 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00824 S100141_00825 S100141_00825 S100141_00825 730100 730756 + Phage-like element PBSX protein XkdP Contains 1 LysM repeat gene gene824 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00825 S100141_00826 S100141_00826 S100141_00826 730813 731793 + Phage-like element PBSX protein XkdQ To B. subtilis YqbQ gene gene825 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00826 S100141_00827 S100141_00827 S100141_00827 731790 732098 + Phage-like element PBSX protein XkdR To B. subtilis YqbR gene gene826 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00827 S100141_00828 S100141_00828 S100141_00828 732117 732542 + Phage-like element PBSX protein XkdS To B. subtilis YqbS gene gene827 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00828 S100141_00829 S100141_00829 S100141_00829 732535 733578 + Phage-like element PBSX protein XkdT Belongs to the Mu gp47/PBSX XkdT family gene gene828 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00829 S100141_00830 S100141_00830 S100141_00830 733565 734485 + Phage-like element PBSX protein XkdU To B. subtilis YqcA gene gene829 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00830 S100141_00831 S100141_00831 S100141_00831 734499 734885 + hypothetical protein gene gene830 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00831 S100141_00832 S100141_00832 S100141_00832 734901 736106 + Phage-like element PBSX protein XkdV To B. subtilis YqcC gene gene831 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00832 S100141_00833 S100141_00833 S100141_00833 736144 737175 + SPBc2 prophage-derived uncharacterized protein YomR Coiled coil. gene gene832 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00833 S100141_00834 S100141_00834 S100141_00834 737278 737547 + putative 11.0 kDa protein in cwlL 5'region To B. licheniformis xpaL1 and to B. subtilis XhlA gene gene833 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00834 S100141_00835 S100141_00835 S100141_00835 737562 737825 + putative 9.5 kDa protein in ORF3 5'region Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the SPP1 holin family gene gene834 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00835 S100141_00836 S100141_00836 S100141_00836 737876 738940 + N-acetylmuramoyl-L-alanine amidase Cell wall biogenesis/degradation%3B Hydrolase%3B Repeat%3B Secreted%3B Signal%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B KEGG: bli:BL01582 N-acetylmuramoyl-L-alanine amidase gene gene835 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00836 S100141_00837 S100141_00837 S100141_00837 739042 739719 + HTH-type transcriptional repressor RspR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Repressor of the rspAB operon. Acts by binding directly to the upstream region of rspA%3B Contains 1 HTH gntR-type DNA-binding domain gene gene836 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00837 S100141_00838 S100141_00838 rspB rspB 739742 740758 + L-gulonate 5-dehydrogenase Metal-binding%3B NADP%3B Oxidoreductase%3B Zinc%3B Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the acryloyl- CoA dependent NADPH oxidation and formation of propionyl-CoA%3B Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: bli:BL03803 L-gulonate 5-dehydrogenase gene gene837 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00838 S100141_00839 S100141_00839 uxuA uxuA 740779 741876 + Mannonate dehydratase Iron%3B Lyase%3B Manganese%3B Catalyzes the dehydration of D-mannonate%3B Belongs to the mannonate dehydratase family%3B KEGG: bli:BL03802 mannonate dehydratase gene gene838 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00839 S100141_00840 S100141_00840 S100141_00840 741852 742700 + putative oxidoreductase UxuB Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bli:BL03801 null%3B Oxidoreductases gene gene839 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00840 S100141_00841 S100141_00841 S100141_00841 742727 743740 + L-galactonate-5-dehydrogenase Metal-binding%3B NAD%3B Oxidoreductase%3B Zinc%3B Catalyzes the oxidation of L-galactonate to D- tagaturonate. Required for growth on L-galactonate as the sole carbon source. In vitro%2C can also use L-gulonate%3B Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: bli:BL03800 null%3B With NAD(+) or NADP(+) as acceptor gene gene840 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00841 S100141_00842 S100141_00842 S100141_00842 743793 745064 + Hexuronate transporter Cell inner membrane%3B Cell membrane%3B Membrane%3B Signal%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Aldohexuronate transport system%3B Belongs to the major facilitator superfamily. Phthalate permease family gene gene841 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00842 S100141_00843 S100141_00843 S100141_00843 745354 745527 - Stage II sporulation protein SB Sporulation%3B Antitoxin component of a toxin-antitoxin (TA) module. Antitoxin that binds cognate toxin SpoIISA and neutralizes its toxic activit%3B unlike most antitoxins it does not seem to be highly labile upon expression in E. coli%3B Belongs to the SpoIISB antitoxin family gene gene842 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00843 S100141_00844 S100141_00844 S100141_00844 745527 746273 - Stage II sporulation protein SA Cell membrane%3B Membrane%3B Sporulation%3B Toxin%3B Transmembrane%3B Transmembrane helix%3B Toxic component of a toxin-antitoxin (TA) module. Its toxic activity is neutralized by cognate antitoxin SpoIISB. Expression in the absence of SpoIISB permits sporulation to stage II%2C when plasmolysis zones and holes in the peptidoglycan layer are observed%2C resulting in cell death. Lethal when synthesized during vegetative growth in the absence of SpoIISB. In E. coli both the membrane bound and soluble domain are required in cis for toxin activity%3B Belongs to the SpoIISA toxin family gene gene843 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00844 S100141_00845 S100141_00845 S100141_00845 746384 747382 - putative low-affinity inorganic phosphate transporter Cell membrane%3B Membrane%3B Phosphate transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Low-affinity inorganic phosphate transport%3B Belongs to the inorganic phosphate transporter (PiT) (TC 2. A. 20) family. Pit subfamily gene gene844 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00845 S100141_00846 S100141_00846 S100141_00846 747395 748012 - UPF0111 protein YkaA Belongs to the UPF0111 family gene gene845 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00846 S100141_00847 S100141_00847 S100141_00847 748344 750101 + Gamma-glutamyltransferase Acyltransferase%3B Glutathione biosynthesis%3B Hydrolase%3B Protease%3B Secreted%3B Signal%3B Transferase%3B Zymogen%3B Belongs to the gamma-glutamyltransferase family%3B KEGG: bli:BL03798 gamma-glutamyltranspeptidase / glutathione hydrolase gene gene846 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00847 S100141_00848 S100141_00848 S100141_00848 750230 750475 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B overlaps another CDS with the same product name gene gene847 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00848 S100141_00849 S100141_00849 S100141_00849 750472 750873 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B overlaps another CDS with the same product name gene gene848 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00849 S100141_00850 S100141_00850 yesM yesM 750887 752623 + Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system YesM/YesN. Probably activates YesN by phosphorylation%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: bli:BL03796 two-component system%2C sensor histidine kinase YesM gene gene849 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00850 S100141_00851 S100141_00851 S100141_00851 752623 752982 + putative transcriptional regulatory protein YesN Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system YesM/YesN%3B Contains 1 HTH araC/xylS-type DNA-binding domain%3B Contains 1 response regulatory domain%3B overlaps another CDS with the same product name gene gene850 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00851 S100141_00852 S100141_00852 S100141_00852 752979 753791 + putative transcriptional regulatory protein YesN Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system YesM/YesN%3B Contains 1 HTH araC/xylS-type DNA-binding domain%3B Contains 1 response regulatory domain%3B overlaps another CDS with the same product name gene gene851 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00852 S100141_00853 S100141_00853 S100141_00853 753938 755233 + Putative ABC transporter substrate-binding protein YesO May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls%3B Belongs to the bacterial solute-binding protein 1 family gene gene852 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00853 S100141_00854 S100141_00854 S100141_00854 755286 756185 + putative ABC transporter permease protein YesP Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene853 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00854 S100141_00855 S100141_00855 S100141_00855 756189 757082 + putative ABC transporter permease protein YesQ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene854 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00855 S100141_00856 S100141_00856 yteR yteR 757100 758134 + Unsaturated rhamnogalacturonyl hydrolase Cytoplasm%3B Glycosidase%3B Hydrolase%3B Catalyzes the hydrolysis of unsaturated rhamnogalacturonan disaccharide to yield unsaturated D- galacturonic acid and L-rhamnose. It cannot act on unsaturated glucuronyl hydrolase (UGL) substrates containing unsaturated D- glucuronic acid at the non-reducing terminus%2C although the active pockets of YesR and UGL are very similar%3B Belongs to the glycosyl hydrolase 105 family%3B KEGG: bli:BL03791 unsaturated rhamnogalacturonyl hydrolase gene gene855 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00856 S100141_00857 S100141_00857 S100141_00857 758182 760464 + HTH-type transcriptional regulator YesS Cell membrane%3B DNA-binding%3B Membrane%3B Transcription%3B Transcription regulation%3B Transmembrane%3B Transmembrane helix%3B Probable transcription factor regulating the pathway responsible for rhamnogalacturonan depolymerization. Contains 1 HTH araC/xylS-type DNA-binding domain gene gene856 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00857 S100141_00858 S100141_00858 S100141_00858 760478 761194 + Rhamnogalacturonan acetylesterase RhgT Hydrolase%3B May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls. This enzyme has a broad substrate specificity%2C and shows strong preference for glucose pentaacetate%2C beta-naphthylacetate%2C and p-nitrophenyl acetate (pNPA). Also active toward acetylated xylan%3B Belongs to the 'GDSL' lipolytic enzyme family gene gene857 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00858 S100141_00859 S100141_00859 S100141_00859 761181 761873 + uncharacterized protein gene gene858 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00859 S100141_00860 S100141_00860 S100141_00860 761888 762499 + uncharacterized protein gene gene859 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00860 S100141_00861 S100141_00861 yesW yesW 762682 764550 + Rhamnogalacturonan endolyase Calcium%3B Cell wall biogenesis/degradation%3B Lyase%3B Metal-binding%3B Secreted%3B Signal%3B Pectinolytic enzyme that degrades type I rhamnogalacturonan from plant cell walls and releases oligosaccharide products. Degrades rhamnogalacturonan%2C polygalacturonic acid%2C pectic acid and pectin%3B Belongs to the polysaccharide lyase 11 family%3B KEGG: bli:BL03786 rhamnogalacturonan endolyase gene gene860 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00861 S100141_00862 S100141_00862 S100141_00862 764571 764729 + hypothetical protein gene gene861 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00862 S100141_00863 S100141_00863 S100141_00863 764726 765040 + hypothetical protein gene gene862 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00863 S100141_00864 S100141_00864 S100141_00864 765081 766199 + Rhamnogalacturonan acetylesterase RhgT Hydrolase%3B May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls. This enzyme has a broad substrate specificity%2C and shows strong preference for glucose pentaacetate%2C beta-naphthylacetate%2C and p-nitrophenyl acetate (pNPA). Also active toward acetylated xylan%3B Belongs to the 'GDSL' lipolytic enzyme family gene gene863 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00864 S100141_00865 S100141_00865 yesX yesX 766268 768154 + Rhamnogalacturonan exolyase Calcium%3B Cell wall biogenesis/degradation%3B Lyase%3B Metal-binding%3B Secreted%3B Signal%3B Pectinolytic enzyme that degrades type I rhamnogalacturonan from plant cell walls and releases oligosaccharide products. Degrades rhamnogalacturonan%2C polygalacturonic acid%2C pectic acid and pectin%3B Belongs to the polysaccharide lyase 11 family%3B KEGG: bli:BL03783 rhamnogalacturonan exolyase gene gene864 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00865 S100141_00866 S100141_00866 S100141_00866 768299 769291 + L-glyceraldehyde 3-phosphate reductase Oxidoreductase%3B Catalyzes the stereospecific%2C NADPH-dependent reduction of L-glyceraldehyde 3-phosphate (L-GAP). The physiological role of gpr is the detoxification of L-GAP%2C which may be formed by non- enzymatic racemization of GAP. Also involved in the stress response as a methylglyoxal reductase which converts the toxic metabolite methylglyoxal to acetol in vitro and in vivo (By similarity)%3B Belongs to the shaker potassium channel beta subunit family%3B KEGG: bli:BL03782 L-glyceraldehyde 3-phosphate reductase%3B With NAD(+) or NADP(+) as acceptor gene gene865 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00866 S100141_00867 S100141_00867 rgaE rgaE 769308 769952 + Rhamnogalacturonan acetylesterase Hydrolase%3B May play a role in the degradation of rhamnogalacturonan derived from plant cell walls. Probably has broad substrate specificity and may degrade several types of acetylated substrates%3B Belongs to the 'GDSL' lipolytic enzyme family%3B KEGG: adl:AURDEDRAFT_140474 rhamnogalacturonan acetylesterase gene gene866 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00867 S100141_00868 S100141_00868 lacZ lacZ 769949 771946 + Beta-galactosidase Glycosidase%3B Hydrolase%3B Metal-binding%3B Zinc%3B May play a role in the degradation of rhamnogalacturonan derived from plant cell walls%3B Belongs to the glycosyl hydrolase 42 family%3B KEGG: bld:BLi01382 beta-galactosidase gene gene867 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00868 S100141_00869 S100141_00869 S100141_00869 772121 774712 + uncharacterized protein gene gene868 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00869 S100141_00870 S100141_00870 S100141_00870 774798 776321 + Lipoprotein LipO Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal. gene gene869 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00870 S100141_00871 S100141_00871 S100141_00871 776363 777316 + Protein LplB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene870 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00871 S100141_00872 S100141_00872 S100141_00872 777335 778219 + Protein LplC Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene871 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00872 S100141_00873 S100141_00873 S100141_00873 778257 779585 - Serine/threonine exchanger SteT Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Exhibits an obligate exchange activity for serine%2C threonine and aromatic amino acids%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2. A. 3. 8) family gene gene872 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00873 S100141_00874 S100141_00874 S100141_00874 779905 780858 + Putative ring-cleaving dioxygenase MhqA Aromatic hydrocarbons catabolism%3B Cytoplasm%3B Detoxification%3B Dioxygenase%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Putative ring-cleavage dioxygenase that may contribute to the degradation of aromatic compounds%3B Belongs to the extradiol ring-cleavage dioxygenase family gene gene873 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00874 S100141_00875 S100141_00875 S100141_00875 781251 781613 + hypothetical protein gene gene874 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00875 S100141_00876 S100141_00876 degP degP 781787 783088 - Peptidase Do Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Serine protease%3B Stress response%3B Transmembrane%3B Transmembrane helix%3B Degrades abnormal exported proteins and responsible for the propeptide processing of a natural pro-protein and for the maturation of a native protein. It also plays a prominent role in stress (heat shock%2C ethanol%2C puromycin and NaCl) resistance during active exponential growth (Probable)%3B Belongs to the peptidase S1C family%3B Contains 1 PDZ (DHR) domain%3B KEGG: blh:BaLi_c15300 serine protease Do gene gene875 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00876 S100141_00877 S100141_00877 proC proC 783244 784056 + Pyrroline-5-carboxylate reductase Alternative splicing%3B Amino-acid biosynthesis%3B Cytoplasm%3B NADP%3B Oxidoreductase%3B Proline biosynthesis%3B Belongs to the pyrroline-5-carboxylate reductase family%3B KEGG: bli:BL03773 pyrroline-5-carboxylate reductase gene gene876 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00877 S100141_00878 S100141_00878 S100141_00878 784272 785096 + D-aminopeptidase Aminopeptidase%3B Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Sporulation%3B Zinc%3B Hydrolyzes N-terminal residues in D-amino acid containing peptides. Among the tested substrates%2C the highest activities are with D-Ala-D-Ala and D-Ala-Gly-Gly. The physiological role is not clear. Belongs to the peptidase M55 family%3B KEGG: bsu:BSU12920 D-amino peptidase%3B Aminopeptidases gene gene877 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00878 S100141_00879 S100141_00879 S100141_00879 785112 786038 + Oligopeptide transport system permease protein OppB Cell membrane%3B Competence%3B Membrane%3B Peptide transport%3B Protein transport%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system for oligopeptide%3B probably responsible for the translocation of the substrate across the membrane. Also required for sporulation and competence. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene878 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00879 S100141_00880 S100141_00880 S100141_00880 786043 787002 + Dipeptide transport system permease protein DppC Cell membrane%3B Membrane%3B Peptide transport%3B Protein transport%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system for dipeptide%3B probably responsible for the translocation of the substrate across the membrane. Is expressed to facilitate adaptation to nutrient deficiency conditions%2C which also induce sporulation. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene879 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00880 S100141_00881 S100141_00881 nrtC nrtC 787010 788008 + Oligopeptide transport ATP-binding protein AmiF ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Peptide transport%3B Protein transport%3B Transport%3B Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: azo:azo0944 nitrate/nitrite transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene880 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00881 S100141_00882 S100141_00882 S100141_00882 788042 789667 + Dipeptide-binding protein DppE Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Peptide transport%3B Protein transport%3B Signal%3B Sporulation%3B Transport%3B Part of the binding-protein-dependent transport system for dipeptide%3B probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions%2C which also induce sporulation. Belongs to the bacterial solute-binding protein 5 family gene gene881 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00882 S100141_00883 S100141_00883 ldcA ldcA 789750 790673 + Muramoyltetrapeptide carboxypeptidase Carboxypeptidase%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Hydrolase%3B Protease%3B Serine protease%3B May be involved in the degradation of peptidoglycan by catalyzing the cleavage of the terminal D-alanine residue from cytoplasmic murein peptides%3B Belongs to the peptidase S66 family%3B KEGG: bli:BL03766 muramoyltetrapeptide carboxypeptidase gene gene882 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00883 S100141_00884 S100141_00884 catB catB 790691 791788 + Muconate cycloisomerase Cell wall biogenesis/degradation%3B Isomerase%3B Magnesium%3B Metal-binding%3B Catalyzes the epimerization of L-Ala-D-Glu to L-Ala-L- Glu and has probably a role in the metabolism of the murein peptide%2C of which L-Ala-D-Glu is a component. Is also able to catalyze the reverse reaction and the epimerization of the other Ala-X dipeptides L-Ala-L-Asp%2C L-Ala-L-Leu%2C L-Ala-L-Met%2C and L-Ala- L-Ser. Is not able to epimerize other L-Ala-X dipeptides. Is also active with L-Ser-L-Glu and%2C oddly%2C L-Pro-L-Glu%2C but not with L- Glu-L-Glu%2C L-Lys-L-Glu%2C L-Lys-L-Ala%2C or D-Ala-D-Ala%3B Belongs to the mandelate racemase/muconate lactonizing enzyme family%3B KEGG: pol:Bpro_4404 muconate cycloisomerase gene gene883 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00884 S100141_00885 S100141_00885 S100141_00885 791785 792672 + Gamma-D-glutamyl-L-lysine endopeptidase Cell wall biogenesis/degradation%3B Hydrolase%3B Protease%3B Thiol protease%3B Specifically hydrolyzes gamma-D-glutamyl-L-lysine bonds in murein peptides%2C releasing L-Ala-D-Glu%3B Belongs to the peptidase C40 family%3B KEGG: bco:Bcell_3074 peptidoglycan endopeptidase LytE%3B Acting on peptide bonds (peptidases) gene gene884 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00885 S100141_00886 S100141_00886 S100141_00886 792692 793705 + Putative oligopeptide transport ATP-binding protein YkfD ATP-binding%3B Hydrolase%3B Nucleotide-binding%3B Transport%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene885 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00886 S100141_00887 S100141_00887 ddaH ddaH 793799 794686 - Dimethylargininase Hydrolase%3B Belongs to the DDAH family%3B KEGG: scb:SCAB_13451 dimethylargininase gene gene886 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00887 S100141_00888 S100141_00888 S100141_00888 794877 795395 + Acyl-CoA hydrolase Hydrolase%3B Belongs to the acyl coenzyme A hydrolase family%3B Contains 1 HotDog ACOT-type domain%3B KEGG: ban:BA_2053 acyl-CoA hydrolase gene gene887 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00888 S100141_00889 S100141_00889 S100141_00889 795506 796249 + UPF0702 transmembrane protein YkjA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0702 family gene gene888 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00889 S100141_00890 S100141_00890 S100141_00890 796459 797766 + Pectate lyase Calcium%3B Lyase%3B Metal-binding%3B Secreted%3B Signal%3B Produces unsaturated products from polygalacturonate. Belongs to the polysaccharide lyase 1 family%3B KEGG: bli:BL03760 pectate lyase gene gene889 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00890 S100141_00891 S100141_00891 S100141_00891 797886 798218 + Putative DNA-binding protein YizB DNA-binding. gene gene890 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00891 S100141_00892 S100141_00892 S100141_00892 798223 798699 + hypothetical protein gene gene891 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00892 S100141_00893 S100141_00893 S100141_00893 798788 798946 + hypothetical protein gene gene892 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00893 S100141_00894 S100141_00894 S100141_00894 799039 799302 + hypothetical protein gene gene893 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00894 S100141_00895 S100141_00895 S100141_00895 799537 800058 + uncharacterized protein gene gene894 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00895 S100141_00896 S100141_00896 S100141_00896 800268 800597 + Multidrug resistance protein YkkC Antibiotic resistance%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of a multidrug efflux pump. Confers resistance to a broad range of toxic compounds such as cationic dyes%2C neutral and anionic antimicrobials (By similarity)%3B Belongs to the small multidrug resistance (SMR) protein family. YkkC/YkkD (TC 2. A. 7. 1. 5) subfamily gene gene895 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00896 S100141_00897 S100141_00897 S100141_00897 800597 800911 + Multidrug resistance protein YkkD Antibiotic resistance%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of a multidrug efflux pump. Confers resistance to a broad range of toxic compounds such as cationic dyes%2C neutral and anionic antimicrobials (By similarity)%3B Belongs to the small multidrug resistance (SMR) protein family. YkkC/YkkD (TC 2. A. 7. 1. 5) subfamily gene gene896 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00897 S100141_00898 S100141_00898 purU purU 801016 801918 + Formyltetrahydrofolate deformylase Hydrolase%3B One-carbon metabolism%3B Purine biosynthesis%3B Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)%3B Belongs to the PurU family%3B Contains 1 ACT domain%3B KEGG: bli:BL03753 formyltetrahydrofolate deformylase gene gene897 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00898 S100141_00899 S100141_00899 proB proB 802257 803354 + Glutamate 5-kinase Amino-acid biosynthesis%3B ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Proline biosynthesis%3B Transferase%3B Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate%3B Belongs to the glutamate 5-kinase family%3B Contains 1 PUA domain%3B KEGG: rma:Rmag_0413 glutamate 5-kinase gene gene898 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00899 S100141_00900 S100141_00900 proA proA 803367 804614 + Glutamate-5-semialdehyde dehydrogenase Amino-acid biosynthesis%3B Cytoplasm%3B NADP%3B Oxidoreductase%3B Proline biosynthesis%3B Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate%3B Belongs to the gamma-glutamyl phosphate reductase family%3B KEGG: bli:BL03751 glutamate-5-semialdehyde dehydrogenase gene gene899 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00900 S100141_00901 S100141_00901 S100141_00901 804725 805147 + Organic hydroperoxide resistance protein OhrA Involved in organic hydroperoxide resistance%3B Belongs to the OsmC/Ohr family gene gene900 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00901 S100141_00902 S100141_00902 mtaP mtaP 805189 805641 - S-methyl-5'-thioadenosine phosphorylase Cytoplasm%3B DNA-binding%3B Oxidation%3B Repressor%3B Transcription%3B Transcription regulation%3B Organic peroxide sensor. Represses the expression of the peroxide-inducible gene ohrA by cooperative binding to two inverted repeat elements%3B Contains 1 HTH marR-type DNA-binding domain%3B KEGG: tmr:Tmar_1098 5'-methylthioadenosine phosphorylase gene gene901 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00902 S100141_00903 S100141_00903 S100141_00903 805801 806214 + Organic hydroperoxide resistance protein OhrB Stress response%3B Involved in organic hydroperoxide resistance%3B Belongs to the OsmC/Ohr family gene gene902 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00903 S100141_00904 S100141_00904 S100141_00904 806286 806951 + hypothetical protein gene gene903 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00904 S100141_00905 S100141_00905 guaD guaD 806981 807451 - Guanine deaminase Hydrolase%3B Metal-binding%3B Purine metabolism%3B Zinc%3B Catalyzes the hydrolytic deamination of guanine%2C producing xanthine and ammonia%3B Belongs to the cytidine and deoxycytidylate deaminase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: bli:BL03735 guanine deaminase gene gene904 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00905 S100141_00906 S100141_00906 gpmB gpmB 807598 808230 + Phosphoglycerate mutase (2%2C3-diphosphoglycerate-independent) Cobalamin biosynthesis%3B Hydrolase%3B Catalyzes the conversion of adenosylcobalamin 5'- phosphate to adenosylcobalamin (vitamin B12%3B involved in the assembly of the nucleotide loop of cobalamin. Also catalyzes the hydrolysis of the phospho group from alpha-ribazole 5'-phosphate to form alpha-ribazole (By similarity)%3B Belongs to the phosphoglycerate mutase family%3B KEGG: bli:BL03733 probable phosphoglycerate mutase gene gene905 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00906 S100141_00907 S100141_00907 S100141_00907 808273 808986 - hypothetical protein gene gene906 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00907 S100141_00908 S100141_00908 S100141_00908 808983 809297 - hypothetical protein gene gene907 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00908 S100141_00909 S100141_00909 metE metE 809505 811793 - 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase Amino-acid biosynthesis%3B Metal-binding%3B Methionine biosynthesis%3B Methyltransferase%3B Repeat%3B Transferase%3B Zinc%3B Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation%3B Belongs to the vitamin-B12 independent methionine synthase family%3B KEGG: bli:BL03738 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase gene gene908 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00909 S100141_00910 S100141_00910 S100141_00910 812264 813217 - Major intracellular serine protease Cytoplasm%3B Hydrolase%3B Protease%3B Serine protease%3B Zymogen%3B Major intracellular protease produced by Bacillus subtilis. Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bli:BL03740 major intracellular serine protease%3B Serine endopeptidases gene gene909 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00910 S100141_00911 S100141_00911 S100141_00911 813510 813665 + uncharacterized protein gene gene910 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00911 S100141_00912 S100141_00912 S100141_00912 814218 815573 + Magnesium transporter MgtE CBS domain%3B Cell membrane%3B Magnesium%3B Membrane%3B Metal-binding%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Acts as a magnesium transporter%3B Belongs to the SLC41A transporter family%3B Contains 2 CBS domains gene gene911 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00912 S100141_00913 S100141_00913 S100141_00913 815666 816073 + hypothetical protein gene gene912 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00913 S100141_00914 S100141_00914 S100141_00914 816104 816436 - HTH-type transcriptional regulator TnrA Activator%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Regulator of transcription that activates or represses many genes during nitrogen-limited growt%3B among others%2C it activates nrgAB%2C nasABCDE%2C gabP%2C and represses glnRA%3B Contains 1 HTH merR-type DNA-binding domain gene gene913 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00914 S100141_00915 S100141_00915 S100141_00915 816629 816784 + uncharacterized protein Coiled coil. gene gene914 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00915 S100141_00916 S100141_00916 S100141_00916 816891 817070 + Stress response protein YkoL Stress response. gene gene915 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00916 S100141_00917 S100141_00917 S100141_00917 817012 817107 + hypothetical protein gene gene916 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00917 S100141_00918 S100141_00918 S100141_00918 817244 817705 + putative HTH-type transcriptional regulator YkoM DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH marR-type DNA-binding domain gene gene917 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00918 S100141_00919 S100141_00919 ligD ligD 817711 819561 - DNA ligase (ATP) ATP-binding%3B DNA damage%3B DNA recombination%3B DNA repair%3B DNA-binding%3B DNA-directed DNA polymerase%3B Exonuclease%3B Hydrolase%3B Ligase%3B Manganese%3B Metal-binding%3B Multifunctional enzyme%3B Nuclease%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Sporulation%3B Transferase%3B Probably involved in DNA repair during spore germination%3B The preference of the polymerase domain for rNTPs over dNTPs may be advantageous in dormant cells%2C where the dNTP pool may be limiting%3B In the N-terminal sectio%3B belongs to the LigD polymerase family%3B In the C-terminal sectio%3B belongs to the ATP- dependent DNA ligase family gene gene918 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00919 S100141_00920 S100141_00920 S100141_00920 819565 820437 - Non-like proteinous end joining protein Ku DNA damage%3B DNA recombination%3B DNA repair%3B DNA-binding%3B Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD (By similarity). Probably involved in DNA repair during spore germination%3B Belongs to the prokaryotic Ku family%3B Contains 1 Ku domain gene gene919 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00920 S100141_00921 S100141_00921 S100141_00921 820591 822243 - putative signaling protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Contains 1 EAL domain%3B Contains 1 GGDEF domain%3B Contains 1 MHYT domain%3B KEGG: she:Shewmr4_0791 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene920 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00921 S100141_00922 S100141_00922 S100141_00922 822563 823174 + putative membrane protein YkoX Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the DedA family gene gene921 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00922 S100141_00923 S100141_00923 S100141_00923 823446 824213 + putative membrane protein YkoY Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the TerC family gene gene922 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00923 S100141_00924 S100141_00924 S100141_00924 824506 825261 + RNA polymerase sigma factor SigI DNA-binding%3B Sigma factor%3B Stress response%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor plays a role in survival at low temperatures and could be involved in heat shock stress response%2C positively regulating the expression of genes such as bcrC and mreBH during this stress%3B Belongs to the sigma-70 factor family gene gene923 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00924 S100141_00925 S100141_00925 prxQ prxQ 825258 826349 + Peroxiredoxin Cell membrane%3B Membrane%3B Stress response%3B Transmembrane%3B Transmembrane helix%3B Anti-sigma factor for SigI. Negatively regulates SigI activity through direct interaction%3B KEGG: smp:SMAC_05546 peroxiredoxin Q/BCP gene gene924 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00925 S100141_00926 S100141_00926 S100141_00926 826362 826559 - Small%2C acid-soluble spore protein C3 DNA-binding%3B Sporulation%3B SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. Belongs to the alpha/beta-type SASP family gene gene925 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00926 S100141_00927 S100141_00927 S100141_00927 826690 827409 - uncharacterized protein gene gene926 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00927 S100141_00928 S100141_00928 htpX htpX 827551 828444 + Protease HtpX like protein Cell membrane%3B Hydrolase%3B Membrane%3B Metal-binding%3B Metalloprotease%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Zinc%3B Belongs to the peptidase M48B family%3B KEGG: bsu:BSU13490 heat shock protein HtpX%3B Metalloendopeptidases gene gene927 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00928 S100141_00929 S100141_00929 S100141_00929 828591 829940 + Potassium/sodium uptake protein NtpJ Cell membrane%3B Ion transport%3B Membrane%3B Potassium%3B Potassium transport%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mediates electrogenic transport of potassium as well as sodium. Acts probably as a potassium-sodium cotransporter. Major sodium reentry pathway at high pH values%3B Belongs to the TrkH potassium transport family gene gene928 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00929 S100141_00930 S100141_00930 S100141_00930 830053 832053 + Penicillin-binding protein Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Peptidoglycan synthesis%3B Transmembrane%3B Transmembrane helix%3B Belongs to the transpeptidase family gene gene929 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00930 S100141_00931 S100141_00931 S100141_00931 832101 832316 + uncharacterized protein overlaps another CDS with the same product name gene gene930 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00931 S100141_00932 S100141_00932 S100141_00932 832313 832501 + uncharacterized protein overlaps another CDS with the same product name gene gene931 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00932 S100141_00933 S100141_00933 S100141_00933 832554 833579 - Putative membrane-bound acyltransferase YkrP Acyltransferase%3B Cell membrane%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Belongs to the acyltransferase 3 family gene gene932 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00933 S100141_00934 S100141_00934 kinE kinE 833889 835724 + Histidine kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Phosphoprotein%3B Repeat%3B Sporulation%3B Transferase%3B Two-component regulatory system%3B Phosphorylates the sporulation-regulatory protein spo0A under biofilm growth conditions. Also able to weakly phosphorylate spo0F%3B Contains 1 histidine kinase domain%3B Contains 4 PAS (PER-ARNT-SIM) domains%3B KEGG: bli:BL03536 two-component system%2C sporulation sensor kinase E%3B overlaps another CDS with the same product name gene gene933 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00934 S100141_00935 S100141_00935 S100141_00935 835673 836098 + Histidine kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Phosphoprotein%3B Repeat%3B Sporulation%3B Transferase%3B Two-component regulatory system%3B Phosphorylates the sporulation-regulatory protein spo0A under biofilm growth conditions. Also able to weakly phosphorylate spo0F%3B Contains 1 histidine kinase domain%3B Contains 4 PAS (PER-ARNT-SIM) domains%3B KEGG: bli:BL03536 two-component system%2C sporulation sensor kinase E%3B overlaps another CDS with the same product name gene gene934 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00935 S100141_00936 S100141_00936 mgmT mgmT 836106 836603 + Methylated-DNA--[protein]-cysteine S-methyltransferase Cytoplasm%3B DNA damage%3B DNA repair%3B Methyltransferase%3B Transferase%3B Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated%3B Belongs to the MGMT family%3B KEGG: bli:BL03537 methylated-DNA-(protein)-cysteine S-methyltransferase gene gene935 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00936 S100141_00937 S100141_00937 S100141_00937 836695 836808 + hypothetical protein gene gene936 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00937 S100141_00938 S100141_00938 mtnA mtnA 836815 837876 - S-methyl-5-thioribose-1-phosphate isomerase Amino-acid biosynthesis%3B Isomerase%3B Methionine biosynthesis%3B Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)%3B Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily%3B KEGG: bli:BL03632 methylthioribose-1-phosphate isomerase gene gene937 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00938 S100141_00939 S100141_00939 mtnK mtnK 837882 839078 - S-methyl-5-thioribose kinase Amino-acid biosynthesis%3B ATP-binding%3B Kinase%3B Methionine biosynthesis%3B Nucleotide-binding%3B Transferase%3B Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate%3B Belongs to the methylthioribose kinase family%3B KEGG: bli:BL03633 5-methylthioribose kinase gene gene938 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00939 S100141_00940 S100141_00940 S100141_00940 839390 840169 - Hydrolase MtnU Hydrolase%3B May be involved in a regulatory step in the methylthioribose (MTR) recycling pathway%3B Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family%3B Contains 1 CN hydrolase domain gene gene939 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00940 S100141_00941 S100141_00941 mtnE mtnE 840265 841455 + putative aspartate aminotransferase Aminotransferase%3B Cytoplasm%3B Pyridoxal phosphate%3B Transferase%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bli:BL03539 aminotransferase%3B Transaminases gene gene940 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00941 S100141_00942 S100141_00942 mtnW mtnW 841689 842906 + 2%2C3-diketo-5-methylthiopentyl-1-phosphate enolase Amino-acid biosynthesis%3B Isomerase%3B Magnesium%3B Metal-binding%3B Methionine biosynthesis%3B Catalyzes the enolization of 2%2C3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)%3B Belongs to the RuBisCO large chain family. Type IV subfamily%3B KEGG: bsu:BSU13590 2%2C3-diketo-5-methylthiopentyl-1-phosphate enolase gene gene941 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00942 S100141_00943 S100141_00943 mtnB mtnB 842903 844186 + Methylthioribulose 1-phosphate dehydratase Amino-acid biosynthesis%3B Hydrolase%3B Lyase%3B Metal-binding%3B Methionine biosynthesis%3B Multifunctional enzyme%3B Zinc%3B Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2%2C3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)%3B Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1%2C2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)%3B In the N-terminal sectio%3B belongs to the HAD-like hydrolase superfamily. MtnX family%3B In the C-terminal sectio%3B belongs to the aldolase class II family. MtnB subfamily%3B KEGG: bli:BL03541 methylthioribulose-1-phosphate dehydratase gene gene942 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00943 S100141_00944 S100141_00944 mtnD mtnD 844207 844746 + Acireductone dioxygenase (Ni(2+)-requiring) Amino-acid biosynthesis%3B Dioxygenase%3B Iron%3B Metal-binding%3B Methionine biosynthesis%3B Nickel%3B Oxidoreductase%3B Catalyzes 2 different reactions between oxygene and the acireductone 1%2C2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB)%2C the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate%2C carbon monoxide and formate%2C and does not lie on the methionine recycle pathway%3B Belongs to the acireductone dioxygenase (ARD) family%3B KEGG: bsu:BSU13620 1%2C2-dihydroxy-3-keto-5-methylthiopentene dioxygenase gene gene943 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00944 S100141_00945 S100141_00945 fosB fosB 844771 845235 - Metallothiol transferase FosB Antibiotic resistance%3B Cytoplasm%3B Magnesium%3B Metal-binding%3B Transferase%3B Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor%3B Belongs to the fosfomycin resistance protein family. FosB subfamily%3B KEGG: bli:BL03635 metallothiol transferase%3B Transferring alkyl or aryl groups%2C other than methyl groups gene gene944 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00945 S100141_00946 S100141_00946 S100141_00946 845222 845551 - putative membrane protein YkvA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene945 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00946 S100141_00947 S100141_00947 S100141_00947 845770 846012 + Aspartyl-phosphate phosphatase Spo0E Hydrolase%3B Sporulation%3B Transcription%3B Transcription regulation%3B Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation%3B Belongs to the spo0E family gene gene946 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00947 S100141_00948 S100141_00948 kinD kinD 846074 847585 - Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Sporulation%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Phosphorylates the sporulation-regulatory protein spo0F and%2C to a minor extent%2C is responsible for heterogeneous expression of spo0A during logarithmical growth. Also phosphorylates spo0A under biofilm growth conditions%3B Contains 1 histidine kinase domain%3B KEGG: bli:BL03637 two-component system%2C sporulation sensor kinase D gene gene947 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00948 S100141_00949 S100141_00949 S100141_00949 847823 848278 + HTH-type transcriptional regulator MhqR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Negatively regulates mhqA%2C mhqED%2C mhqNOP%2C and azoR2 which may contribute to the degradation of aromatic compounds%3B Contains 1 HTH marR-type DNA-binding domain gene gene948 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00949 S100141_00950 S100141_00950 S100141_00950 848303 849082 - Motility protein Cell membrane%3B Chemotaxis%3B Flagellar rotation%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B MotA and MotB comprise the stator element of the flagellar motor complex. Required for the rotation of the flagellar motor. Might be a linker that fastens the torque- generating machinery to the cell wall (By similarity)%3B Belongs to the MotB family%3B Contains 1 OmpA-like domain%3B overlaps another CDS with the same product name gene gene949 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00950 S100141_00951 S100141_00951 S100141_00951 849075 849878 - Motility protein Cell membrane%3B Chemotaxis%3B Flagellar rotation%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel (By similarity)%3B Belongs to the MotA family%3B overlaps another CDS with the same product name gene gene950 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00951 S100141_00952 S100141_00952 S100141_00952 850077 852173 - ATP-dependent Clp protease ATP-binding subunit ClpE ATP-binding%3B Chaperone%3B Metal-binding%3B Nucleotide-binding%3B Stress response%3B Zinc%3B Zinc-finger%3B ATPase essential both for efficient CtsR-dependent gene derepression during heat stress and for rerepression. Together with ClpP%2C degrades the global regulator CtsR after heat shock. Is also involved in disaggregation of heat-denatured proteins. Has thus a role in overall protein quality control in response to heat stress%3B Belongs to the ClpA/ClpB family. ClpE subfamily%3B Contains 1 UVR domain gene gene951 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00952 S100141_00953 S100141_00953 S100141_00953 852394 853428 + putative membrane protein YkvI Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene952 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00953 S100141_00954 S100141_00954 queC queC 853693 854352 + 7-cyano-7-deazaguanine synthase ATP-binding%3B Ligase%3B Metal-binding%3B Nucleotide-binding%3B Queuosine biosynthesis%3B Zinc%3B Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))%3B Belongs to the QueC family%3B KEGG: psh:Psest_1506 7-cyano-7-deazaguanine synthase gene gene953 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00954 S100141_00955 S100141_00955 queD queD 854355 854795 + 6-pyruvoyltetrahydropterin synthase Lyase%3B Metal-binding%3B Queuosine biosynthesis%3B Zinc%3B Catalyzes the conversion of 7%2C8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5%2C6%2C7%2C8-tetrahydropterin (CPH4) and acetaldehyde%3B Belongs to the PTPS family. QueD subfamily%3B KEGG: bsu:BSU13730 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase gene gene954 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00955 S100141_00956 S100141_00956 queE queE 854845 855519 + 7-carboxy-7-deazaguanine synthase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Lyase%3B Metal-binding%3B Queuosine biosynthesis%3B S-adenosyl-L-methionine%3B Catalyzes the conversion of 6-carboxy-5%2C6%2C7%2C8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG)%3B Belongs to the radical SAM superfamily. 7-carboxy-7- deazaguanine synthase family%3B KEGG: ead:OV14_a0984 7-carboxy-7-deazaguanine synthase gene gene955 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00956 S100141_00957 S100141_00957 queF queF 855541 856038 + PreQ(1) synthase Cytoplasm%3B NADP%3B Oxidoreductase%3B Queuosine biosynthesis%3B Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)%3B Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily%3B KEGG: bsu:BSU13750 7-cyano-7-deazaguanine reductase gene gene956 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00957 S100141_00958 S100141_00958 S100141_00958 856711 856836 - hypothetical protein gene gene957 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00958 S100141_00959 S100141_00959 rapH rapH 856826 857107 - Response regulator aspartate phosphatase Hydrolase%3B Protein phosphatase%3B Repeat%3B Sporulation%3B TPR repeat%3B Prevents sporulation by dephosphorylating Spo0F%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: blh:BaLi_c16130 response regulator aspartate phosphatase H%3B Acting on ester bonds%3B overlaps another CDS with the same product name gene gene958 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00959 S100141_00960 S100141_00960 S100141_00960 857100 857483 - Response regulator aspartate phosphatase Hydrolase%3B Protein phosphatase%3B Repeat%3B TPR repeat%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: blh:BaLi_c16130 response regulator aspartate phosphatase H%3B Acting on ester bonds%3B overlaps another CDS with the same product name gene gene959 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00960 S100141_00961 S100141_00961 S100141_00961 857541 857948 - Response regulator aspartate phosphatase Hydrolase%3B Protein phosphatase%3B Repeat%3B TPR repeat%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bld:BLi01578 response regulator aspartate phosphatase H%3B Acting on ester bonds gene gene960 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00961 S100141_00962 S100141_00962 mobA mobA 858331 859122 - Molybdenum cofactor guanylyltransferase Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B KEGG: lmob:BN419_1252 molybdopterin-guanine dinucleotide biosynthesis protein A gene gene961 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00962 S100141_00963 S100141_00963 S100141_00963 859252 859473 - putative HTH-type transcriptional regulator YozG DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene962 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00963 S100141_00964 S100141_00964 S100141_00964 859484 859966 - putative membrane protein YoaS Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene963 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00964 S100141_00965 S100141_00965 S100141_00965 860504 860749 - hypothetical protein gene gene964 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00965 S100141_00966 S100141_00966 S100141_00966 860848 861168 - hypothetical protein gene gene965 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00966 S100141_00967 S100141_00967 S100141_00967 861165 861947 - hypothetical protein gene gene966 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00967 S100141_00968 S100141_00968 S100141_00968 862192 863052 - putative transposase-like protein DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene967 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00968 S100141_00969 S100141_00969 S100141_00969 863022 863354 - hypothetical protein gene gene968 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00969 S100141_00970 S100141_00970 S100141_00970 863614 863958 + hypothetical protein gene gene969 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00970 S100141_00971 S100141_00971 S100141_00971 864576 865430 + hypothetical protein gene gene970 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00971 S100141_00972 S100141_00972 S100141_00972 865786 865974 - uncharacterized protein gene gene971 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00972 S100141_00973 S100141_00973 S100141_00973 866141 866335 + uncharacterized protein gene gene972 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00973 S100141_00974 S100141_00974 S100141_00974 866565 867176 + N-acetylmuramoyl-L-alanine amidase Signal%3B KEGG: bsu:BSU13820 N-acetylmuramoyl-L-alanine amidase gene gene973 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00974 S100141_00975 S100141_00975 S100141_00975 867366 868706 + Sporulation protein YkvU Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix. gene gene974 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00975 S100141_00976 S100141_00976 S100141_00976 868771 869262 + Sporulation thiol-disulfide oxidoreductase Disulfide bond%3B Membrane%3B Oxidoreductase%3B Redox-active center%3B Signal%3B Sporulation%3B Thiol-disulfide oxidoreductase with a reductive function%2C involved in spore cortex synthesis. It could be involved either in breaking disulfide bonds in cortex components or in proteins that are important for cortex synthesis%2C or in thiol/disulfide bond interchange%3B Belongs to the thioredoxin family%3B Contains 1 thioredoxin domain gene gene975 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00976 S100141_00977 S100141_00977 zntA zntA 869517 871424 + Cadmium-exporting ATPase ATP-binding%3B Cell membrane%3B Hydrolase%3B Ion transport%3B Magnesium%3B Membrane%3B Metal-binding%3B Nucleotide-binding%3B Phosphoprotein%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Zinc%3B Zinc transport%3B Couples the hydrolysis of ATP with the transport of zinc into the cell. Plays an important role in protecting cells against oxidative stress. ZosA-mediated zinc transport is required for post-transcriptional control of comK and competence development%3B Belongs to the cation transport ATPase (P-type) (TC 3. A. 3) family. Type IB subfamily%3B KEGG: bli:BL03560 Cd2+/Zn2+-exporting ATPase gene gene976 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00977 S100141_00978 S100141_00978 pepQ pepQ 871627 872721 + Xaa-Pro dipeptidase Hydrolase%3B Manganese%3B Metal-binding%3B Belongs to the peptidase M24B family%3B KEGG: bsu:BSU13860 Xaa-Pro dipeptidase gene gene977 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00978 S100141_00979 S100141_00979 S100141_00979 872785 872919 - hypothetical protein gene gene978 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00979 S100141_00980 S100141_00980 S100141_00980 873411 874136 + hypothetical protein gene gene979 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00980 S100141_00981 S100141_00981 S100141_00981 874361 875332 + Catabolite control protein DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcriptional regulator involved in catabolite repression of several operons. Contains 1 HTH lacI-type DNA-binding domain gene gene980 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00981 S100141_00982 S100141_00982 S100141_00982 875465 876310 + Beta-glucoside operon antiterminator Activator%3B Phosphoprotein%3B Repeat%3B RNA-binding%3B Transcription%3B Transcription regulation%3B Mediates the positive regulation of the beta-glucoside (arb) operon by functioning as a transcriptional antiterminator. This is an RNA-binding protein that recognizes a specific sequence located just upstream of two termination sites within the operon (By similarity)%3B Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains gene gene981 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00982 S100141_00983 S100141_00983 gamP gamP 876532 878628 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Kinase%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport. Contains 1 PTS EIIA type-1 domain%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bli:BL03565 PTS system%2C D-glucosamine-specific IIA component gene gene982 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00983 S100141_00984 S100141_00984 S100141_00984 878729 878995 + Phosphocarrier protein Cytoplasm%3B Kinase%3B Phosphoprotein%3B Phosphotransferase system%3B Serine/threonine-protein kinase%3B Sugar transport%3B Transcription%3B Transcription regulation%3B Transferase%3B Transport%3B General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the permease (enzymes II/III). P-Ser-HPr interacts with the catabolite control protein A (CcpA)%2C forming a complex that binds to DNA at the catabolite response elements cre%2C operator sites preceding a large number of catabolite-regulated genes. Thus%2C P-Ser-HPr is a corepressor in carbon catabolite repression (CCR)%2C a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion%2C in which it probably interacts with several non-PTS permeases and inhibits their transport activity. Belongs to the HPr family%3B Contains 1 HPr domain gene gene983 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00984 S100141_00985 S100141_00985 ptsI ptsI 878995 880713 + Phosphoenolpyruvate--protein phosphotransferase Cytoplasm%3B Kinase%3B Magnesium%3B Metal-binding%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transport%3B General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). Belongs to the PEP-utilizing enzyme family%3B KEGG: bsu:BSU13910 phosphotransferase system%2C enzyme I%2C PtsI gene gene984 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00985 S100141_00986 S100141_00986 S100141_00986 880833 881066 + Transcriptional regulator SplA Transcription%3B Transcription regulation. gene gene985 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00986 S100141_00987 S100141_00987 splB splB 881044 882168 + Spore photoproduct lyase 4Fe-4S%3B DNA damage%3B DNA repair%3B DNA-binding%3B Iron%3B Iron-sulfur%3B Lyase%3B Metal-binding%3B S-adenosyl-L-methionine%3B Sporulation%3B Involved in repair of UV radiation-induced DNA damage during spore germination. Can repair thymine dimer 5-thyminyl-5%2C6- dihydrothymine (known as spore photoproduct (SP)) by in situ monomerization of SP to two thymines%3B Belongs to the radical SAM superfamily. SPL family%3B KEGG: blh:BaLi_c16380 spore photoproduct lyase gene gene986 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00987 S100141_00988 S100141_00988 S100141_00988 882212 882880 - putative N-acetyltransferase YkwB Acyltransferase%3B Transferase%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain gene gene987 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00988 S100141_00989 S100141_00989 S100141_00989 882994 884961 + Methyl-accepting chemotaxis protein McpC Cell membrane%3B Chemotaxis%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpC is required for taxis to cysteine%2C proline%2C threonine%2C glycine%2C serine%2C lysine%2C valine and arginine and for aspartate%2C glutamine%2C histidine and glutamate. Primarily mediates response to positive stimulus of PTS carbohydrates. Greatly influences the duration or magnitude of the response to negative PTS carbohydrate stimulus%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene988 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00989 S100141_00990 S100141_00990 S100141_00990 884979 885854 + 3-oxoacyl-[acyl-carrier-protein] reductase Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B NADP%3B Oxidoreductase%3B Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products%2C the first reductive step in the elongation cycle of fatty acid biosynthesis%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bld:BLi01605 3-oxoacyl-(acyl-carrier protein) reductase gene gene989 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00990 S100141_00991 S100141_00991 mmsB mmsB 885868 886740 + 3-hydroxyisobutyrate dehydrogenase NAD%3B Oxidoreductase%3B Belongs to the 3-hydroxyisobutyrate dehydrogenase family%3B KEGG: bsr:I33_1574 3-hydroxyisobutyrate dehydrogenase gene gene990 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00991 S100141_00992 S100141_00992 S100141_00992 886785 887546 - uncharacterized protein Signal%3B Contains 1 SCP domain gene gene991 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00992 S100141_00993 S100141_00993 S100141_00993 887894 890002 + Penicillin-binding protein Antibiotic resistance%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Peptidoglycan synthesis%3B Transmembrane%3B Transmembrane helix%3B Involved in the polymerization of peptidoglycan. Plays a redundant role with PBP2a in determining the rod shape of the cell during vegetative growth and spore outgrowth%3B Belongs to the transpeptidase family gene gene992 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00993 S100141_00994 S100141_00994 kinA kinA 890163 891974 + Histidine kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Phosphoprotein%3B Repeat%3B Sporulation%3B Transferase%3B Two-component regulatory system%3B Phosphorylates the sporulation-regulatory proteins spo0A and spo0F. It also autophosphorylates in the presence of ATP. Contains 1 histidine kinase domain%3B Contains 2 PAC (PAS-associated C-terminal) domains%3B Contains 3 PAS (PER-ARNT-SIM) domains%3B KEGG: bli:BL03576 two-component system%2C sporulation sensor kinase A gene gene993 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00994 S100141_00995 S100141_00995 patA patA 892006 893175 - Putative N-acetyl-LL-diaminopimelate aminotransferase Amino-acid biosynthesis%3B Aminotransferase%3B Cytoplasm%3B Diaminopimelate biosynthesis%3B Lysine biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B May catalyze the conversion of L-2-acetamido-6- oxopimelate to N-acetyl-LL-2%2C6-diaminopimelate%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bli:BL03647 aminotransferase%3B Transaminases gene gene994 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00995 S100141_00996 S100141_00996 S100141_00996 893367 893525 - hypothetical protein gene gene995 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00996 S100141_00997 S100141_00997 S100141_00997 893697 894221 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene996 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00997 S100141_00998 S100141_00998 S100141_00998 894318 895637 + putative MFS-type transporter YxiO Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene997 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00998 S100141_00999 S100141_00999 S100141_00999 895711 896628 + Chemotaxis protein CheV Chemotaxis%3B Phosphoprotein%3B Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. Chemotaxis involves both a phosphorylation-dependent excitation and a methylation-dependent adaptation. CheV and CheW are involved in the coupling of the methyl-accepting chemoreceptors to the central two-component kinase Che%3B they are both necessary for efficient chemotaxis. Moreover%2C CheA-dependent phosphorylation of CheV is required for adaptation to attractants during B. subtilis chemotaxis%3B Contains 1 cheW-like domain%3B Contains 1 response regulatory domain gene gene998 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_00999 S100141_01000 S100141_01000 S100141_01000 896660 897121 - uncharacterized protein gene gene999 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01000 S100141_01001 S100141_01001 S100141_01001 897263 898564 - dTMP kinase Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily%3B KEGG: abai:IMCC26256_11234 dTMP kinase gene gene1000 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01001 S100141_01002 S100141_01002 S100141_01002 898653 899150 - Putative L%2CD-transpeptidase YkuD Cell shape%3B Cell wall biogenesis/degradation%3B Glycosyltransferase%3B Hydrolase%3B Peptidoglycan synthesis%3B Sporulation%3B Transferase%3B Probable enzyme that may play an important role in cell wall biology%3B Belongs to the YkuD family%3B Contains 1 LysM repeat gene gene1001 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01002 S100141_01003 S100141_01003 S100141_01003 899330 900187 - putative metallophosphoesterase YkuE Hydrolase%3B Metal-binding%3B Signal%3B Belongs to the metallophosphoesterase superfamily gene gene1002 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01003 S100141_01004 S100141_01004 butA butA 900333 901097 + Cyclopentanol dehydrogenase NAD%3B Oxidoreductase%3B Reduces cyclopentanol to cyclopentanone. The enzyme also shows considerable activity toward cyclohexanol (By similarity)%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: ecy:ECSE_P3-0048 meso-butanediol dehydrogenase / (S%2CS)-butanediol dehydrogenase / diacetyl reductase%3B With NAD(+) or NADP(+) as acceptor gene gene1003 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01004 S100141_01005 S100141_01005 S100141_01005 901165 902385 + Protein-glutamate O-methyltransferase Contains 1 EAL domain%3B KEGG: mah:MEALZ_1025 two-component system%2C chemotaxis family%2C CheB/CheR fusion protein gene gene1004 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01005 S100141_01006 S100141_01006 S100141_01006 902496 903122 + hypothetical protein gene gene1005 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01006 S100141_01007 S100141_01007 S100141_01007 903579 903821 + uncharacterized protein Signal. gene gene1006 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01007 S100141_01008 S100141_01008 S100141_01008 903833 903982 + hypothetical protein gene gene1007 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01008 S100141_01009 S100141_01009 S100141_01009 904040 904558 + uncharacterized protein gene gene1008 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01009 S100141_01010 S100141_01010 S100141_01010 904697 904876 + uncharacterized protein gene gene1009 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01010 S100141_01011 S100141_01011 S100141_01011 905057 905500 + CBS domain-containing protein YkuL CBS domain%3B Contains 1 CBS domain gene gene1010 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01011 S100141_01012 S100141_01012 S100141_01012 905643 906518 + putative HTH-type transcriptional regulator YkuM DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH lysR-type DNA-binding domain gene gene1011 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01012 S100141_01013 S100141_01013 S100141_01013 906650 907129 + putative flavodoxin-1 Electron transport%3B Flavoprotein%3B FMN%3B Transport%3B Low-potential electron donor to a number of redox enzymes%3B Belongs to the flavodoxin family%3B Contains 1 flavodoxin-like domain gene gene1012 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01013 S100141_01014 S100141_01014 S100141_01014 907119 908012 + uncharacterized protein gene gene1013 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01014 S100141_01015 S100141_01015 S100141_01015 908042 908494 + putative flavodoxin-2 Electron transport%3B Flavoprotein%3B FMN%3B Transport%3B Low-potential electron donor to a number of redox enzymes%3B Belongs to the flavodoxin family%3B Contains 1 flavodoxin-like domain gene gene1014 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01015 S100141_01016 S100141_01016 dapH dapH 908600 909310 + Tetrahydrodipicolinate N-acetyltransferase Acyltransferase%3B Amino-acid biosynthesis%3B Diaminopimelate biosynthesis%3B Lysine biosynthesis%3B Repeat%3B Transferase%3B Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate%3B Belongs to the transferase hexapeptide repeat family. DapH subfamily%3B KEGG: bsu:BSU14180 tetrahydrodipicolinate N-acetyltransferase gene gene1015 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01016 S100141_01017 S100141_01017 S100141_01017 909380 910504 + N-acetyldiaminopimelate deacetylase Amino-acid biosynthesis%3B Diaminopimelate biosynthesis%3B Hydrolase%3B Lysine biosynthesis%3B Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate%3B Belongs to the peptidase M20A family. N- acetyldiaminopimelate deacetylase subfamily%3B KEGG: bli:BL05143 N-acetyldiaminopimelate deacetylase gene gene1016 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01017 S100141_01018 S100141_01018 S100141_01018 910567 910812 + UPF0180 protein Belongs to the UPF0180 family gene gene1017 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01018 S100141_01019 S100141_01019 prdX prdX 911107 911649 + Peroxiredoxin Belongs to the thioredoxin family%3B Contains 1 thioredoxin domain%3B KEGG: bfr:BF2266 peroxiredoxin (alkyl hydroperoxide reductase subunit C) gene gene1018 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01019 S100141_01020 S100141_01020 S100141_01020 911731 912189 + Thiol-disulfide oxidoreductase YkuV Cytoplasm%3B Disulfide bond%3B Electron transport%3B Oxidoreductase%3B Redox-active center%3B Transport%3B Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Contains 1 thioredoxin domain gene gene1019 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01020 S100141_01021 S100141_01021 S100141_01021 912737 913327 + Repressor rok Coiled coil%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation. gene gene1020 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01021 S100141_01022 S100141_01022 S100141_01022 913474 914430 - Sporulation protein cse15 Coiled coil%3B Sporulation. gene gene1021 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01022 S100141_01023 S100141_01023 S100141_01023 914583 915170 + Molybdenum cofactor guanylyltransferase Cytoplasm%3B GTP-binding%3B Magnesium%3B Metal-binding%3B Molybdenum cofactor biosynthesis%3B Nucleotide-binding%3B Transferase%3B Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor%3B Belongs to the MobA family%3B KEGG: bli:BL00558 molybdopterin-guanine dinucleotide biosynthesis protein A gene gene1022 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01023 S100141_01024 S100141_01024 S100141_01024 915207 916289 + Molybdopterin-synthase adenylyltransferase ATP-binding%3B Metal-binding%3B Molybdenum cofactor biosynthesis%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase%3B Zinc%3B Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein MoaD%3B Belongs to the HesA/MoeB/ThiF family gene gene1023 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01024 S100141_01025 S100141_01025 moeA moeA 916309 917601 + Molybdopterin molybdotransferase Magnesium%3B Metal-binding%3B Molybdenum%3B Molybdenum cofactor biosynthesis%3B Transferase%3B Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP%3B Belongs to the MoeA family%3B KEGG: bsu:BSU14280 molybdopterin molybdotransferase gene gene1024 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01025 S100141_01026 S100141_01026 S100141_01026 917568 918095 + putative molybdopterin-guanine dinucleotide biosynthesis adapter protein GTP-binding%3B Molybdenum cofactor biosynthesis%3B Nucleotide-binding%3B GTP-binding protein that is not required for the biosynthesis of Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor%2C and not necessary for the formation of active molybdoenzymes using this form of molybdenum cofactor. May act as an adapter protein to achieve the efficient biosynthesis and utilization of MGD. Displays a weak intrinsic GTPase activity (By similarity)%3B Belongs to the MobB family gene gene1025 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01026 S100141_01027 S100141_01027 moaE moaE 918250 918567 + Molybdopterin synthase Molybdenum cofactor biosynthesis%3B Transferase%3B Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD (By similarity)%3B Belongs to the MoaE family%3B KEGG: bli:BL00554 molybdopterin synthase catalytic subunit gene gene1026 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01027 S100141_01028 S100141_01028 S100141_01028 918564 918797 + Molybdopterin synthase sulfur carrier subunit Molybdenum cofactor biosynthesis%3B Nucleotide-binding%3B Phosphoprotein%3B Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin%3B Belongs to the MoaD family gene gene1027 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01028 S100141_01029 S100141_01029 S100141_01029 918827 919204 - hypothetical protein gene gene1028 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01029 S100141_01030 S100141_01030 S100141_01030 919471 921228 + Lipid A export ATP-binding/permease protein MsbA ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Lipid transport%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation%3B Belongs to the ABC transporter superfamily. Lipid exporter (TC 3. A. 1. 106) family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene1029 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01030 S100141_01031 S100141_01031 S100141_01031 921241 923061 + putative ABC transporter ATP-binding protein YknV ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene1030 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01031 S100141_01032 S100141_01032 S100141_01032 923181 923861 + Membrane protein YknW Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Part of an unusual four-component transporter%2C which is required for protection against the killing factor SdpC (sporulation-delaying protein). Has a role in the assembly of the YknXYZ complex gene gene1031 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01032 S100141_01033 S100141_01033 S100141_01033 923862 924998 + Putative efflux system component YknX Cell membrane%3B Coiled coil%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Part of an unusual four-component transporter%2C which is required for protection against the killing factor SdpC (sporulation-delaying protein)%3B Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene1032 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01033 S100141_01034 S100141_01034 macB macB 924995 925687 + Macrolide export ATP-binding/permease protein MacB Antibiotic resistance%3B ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD)%2C which form a pore in the inner membrane%2C and an ATP-binding domain (NBD)%2C which is responsible for energy generation. Confers resistance against macrolides%3B Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3. A. 1. 122) family%3B Contains 1 ABC transporter domain%3B KEGG: efe:EFER_1027 macrolide transport system ATP-binding/permease protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene1033 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01034 S100141_01035 S100141_01035 S100141_01035 925684 926877 + putative ABC transporter permease YknZ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of an unusual four-component transporter%2C which is required for protection against the killing factor SdpC (sporulation-delaying protein)%3B Belongs to the ABC-4 integral membrane protein family gene gene1034 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01035 S100141_01036 S100141_01036 S100141_01036 927508 928263 + putative HTH-type transcriptional regulator FruR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH deoR-type DNA-binding domain gene gene1035 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01036 S100141_01037 S100141_01037 pfkB pfkB 928260 929171 + 6-phosphofructokinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the carbohydrate kinase PfkB family%3B KEGG: sty:STY3436 6-phosphofructokinase 2 gene gene1036 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01037 S100141_01038 S100141_01038 fruB fruB 929185 931080 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Membrane%3B Phosphoprotein%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport (By similarity)%3B Contains 1 PTS EIIA type-2 domain%3B Contains 1 PTS EIIB type-2 domain%3B Contains 1 PTS EIIC type-2 domain%3B KEGG: ron:TE10_11530 PTS system%2C fructose-specific IIA component gene gene1037 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01038 S100141_01039 S100141_01039 S100141_01039 931247 931807 + Signal peptidase I Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Belongs to the peptidase S26 family%3B KEGG: bli:BL01607 signal peptidase I gene gene1038 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01039 S100141_01040 S100141_01040 S100141_01040 931853 932122 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1039 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01040 S100141_01041 S100141_01041 S100141_01041 932135 932377 - hypothetical protein gene gene1040 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01041 S100141_01042 S100141_01042 S100141_01042 932550 934169 + Arabinose import ATP-binding protein AraG ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Repeat%3B Sugar transport%3B Transport%3B Part of the ABC transporter complex AraFGH involved in arabinose import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Arabinose importer (TC 3. A. 1. 2. 2) family%3B Contains 2 ABC transporter domains gene gene1041 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01042 S100141_01043 S100141_01043 S100141_01043 934226 934600 + hypothetical protein gene gene1042 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01043 S100141_01044 S100141_01044 S100141_01044 934738 935970 - Aminopeptidase AmpS Aminopeptidase%3B Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Zinc%3B Metal-dependent exopeptidase%3B Belongs to the peptidase M29 family%3B KEGG: bsu:BSU14450 aminopeptidase%3B Aminopeptidases gene gene1043 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01044 S100141_01045 S100141_01045 S100141_01045 936061 936192 - uncharacterized protein Signal. gene gene1044 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01045 S100141_01046 S100141_01046 S100141_01046 936266 937273 - Protein MreBH Belongs to the FtsA/MreB family gene gene1045 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01046 S100141_01047 S100141_01047 S100141_01047 937580 937867 + Putative transition state regulator Abh DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 SpoVT-AbrB domain%3B To B. subtilis AbrB and SpoVT gene gene1046 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01047 S100141_01048 S100141_01048 kinC kinC 938035 939372 + Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Sporulation%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Phosphorylates the sporulation-regulatory protein spo0A. Contains 1 histidine kinase domain%3B Contains 1 PAC (PAS-associated C-terminal) domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bsu:BSU14490 two-component system%2C sporulation sensor kinase C gene gene1047 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01048 S100141_01049 S100141_01049 S100141_01049 939437 940099 + Ktr system potassium uptake protein Cell membrane%3B Ion transport%3B Membrane%3B NAD%3B Potassium%3B Potassium transport%3B Transport%3B Catalytic subunit of the KtrCD potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress%3B Belongs to the KtrA potassium transport family%3B Contains 1 RCK C-terminal domain%3B Contains 1 RCK N-terminal domain gene gene1048 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01049 S100141_01050 S100141_01050 S100141_01050 940239 941948 + Adenine deaminase Hydrolase%3B Manganese%3B Belongs to the adenine deaminase family%3B KEGG: bli:BL01613 adenine deaminase gene gene1049 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01050 S100141_01051 S100141_01051 S100141_01051 942001 943668 - Ribonuclease J1 Calcium%3B Cytoplasm%3B Endonuclease%3B Exonuclease%3B Hydrolase%3B Metal-binding%3B mRNA processing%3B Nuclease%3B RNA-binding%3B rRNA processing%3B Zinc%3B An RNase that has endonuclease and 5'-3' exonuclease activity%2C playing a role in both rRNA and mRNA stability and degradation. Endonuclease activity can cleave within 4 nucleotides of the 5'-end of a triphosphorylated RNA. Endonuclease digestion by the RNase J1/J2 complex occurs at a different site and in some cases more efficiently than J1 or J2 alone. The exonuclease activity of the J1/J2 complex is highly processive on substrates longer than 5 nucleotides%2C on shorter substrates is distributive. Preferentially cleaves ssRNA%2C possibly in AU-rich regions. The 5'- exonuclease activity acts on 5'-hydroxyl and 5'-monophosphate but not 5'-triphosphate end%3B it can digest through stem-loop structures if they are not too stable. Required for maturation of 16S rRNA. Acts preferentially on 16S rRNA precursors after association of the 30S and 50S ribosomal subunits. Plays a role in the secondary pathway of 23S rRNA 5' end maturation. Probably also participates in processing of pre-scRNA (the precursor of the signal recognition particle RNA)%3B Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily%3B KEGG: bsu:BSU14530 ribonuclease J%3B Acting on ester bonds gene gene1050 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01051 S100141_01052 S100141_01052 S100141_01052 943673 943882 - UPF0356 protein Belongs to the UPF0356 family gene gene1051 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01052 S100141_01053 S100141_01053 S100141_01053 944282 945058 + Putative phosphatase YkrA Hydrolase%3B Magnesium%3B Metal-binding%3B Belongs to the HAD-like hydrolase superfamily. Cof family gene gene1052 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01053 S100141_01054 S100141_01054 S100141_01054 945174 946604 + hypothetical protein gene gene1053 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01054 S100141_01055 S100141_01055 S100141_01055 946638 947195 - Peptide deformylase Hydrolase%3B Iron%3B Metal-binding%3B Protein biosynthesis%3B Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. Belongs to the polypeptide deformylase family%3B KEGG: bld:BLi01671 peptide deformylase gene gene1054 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01055 S100141_01056 S100141_01056 S100141_01056 947314 947445 - UPF0752 membrane protein YkzV Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0752 family gene gene1055 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01056 S100141_01057 S100141_01057 S100141_01057 947702 948370 + putative lipoprotein YkyA Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal. gene gene1056 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01057 S100141_01058 S100141_01058 pdhA pdhA 948770 949885 + Pyruvate dehydrogenase (acetyl-transferring) Glycolysis%3B Oxidoreductase%3B Pyruvate%3B Thiamine pyrophosphate%3B KEGG: bsu:BSU14580 pyruvate dehydrogenase E1 component alpha subunit gene gene1057 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01058 S100141_01059 S100141_01059 pdhB pdhB 949889 950866 + Pyruvate dehydrogenase (acetyl-transferring) Glycolysis%3B Oxidoreductase%3B Pyruvate%3B Thiamine pyrophosphate%3B KEGG: rhd:R2APBS1_0530 pyruvate dehydrogenase E1 component beta subunit gene gene1058 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01059 S100141_01060 S100141_01060 dlaT dlaT 951029 952321 + Dihydrolipoyllysine-residue acetyltransferase Acyltransferase%3B Glycolysis%3B Lipoyl%3B Transferase%3B The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1)%2C dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The B. subtilis PDH complex possesses also branched-chain 2-oxoacid dehydrogenase (BCDH) activity. Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: rbu:PG1C_10405 pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) gene gene1059 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01060 S100141_01061 S100141_01061 pdhD pdhD 952326 953738 + Dihydrolipoyl dehydrogenase Cytoplasm%3B Disulfide bond%3B FAD%3B Flavoprotein%3B Glycolysis%3B NAD%3B Oxidoreductase%3B Redox-active center%3B Catalyzes the oxidation of dihydrolipoamide to lipoamide. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: bsu:BSU14610 dihydrolipoamide dehydrogenase gene gene1060 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01061 S100141_01062 S100141_01062 S100141_01062 953769 953927 + hypothetical protein gene gene1061 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01062 S100141_01063 S100141_01063 S100141_01063 953857 954234 - Pal-related lipoprotein Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal. gene gene1062 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01063 S100141_01064 S100141_01064 S100141_01064 954610 954729 + uncharacterized protein gene gene1063 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01064 S100141_01065 S100141_01065 speA speA 954774 956264 - Arginine decarboxylase Cytoplasm%3B Decarboxylase%3B Lyase%3B Polyamine biosynthesis%3B Putrescine biosynthesis%3B Pyridoxal phosphate%3B Spermidine biosynthesis%3B Catalyzes the formation of agmatine from arginine. Belongs to the Orn/Lys/Arg decarboxylase class-I family%3B KEGG: bli:BL01634 arginine decarboxylase gene gene1064 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01065 S100141_01066 S100141_01066 S100141_01066 956502 956777 + UPF0223 protein Belongs to the UPF0223 family gene gene1065 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01066 S100141_01067 S100141_01067 S100141_01067 956829 957464 - UPF0637 protein Belongs to the UPF0637 family gene gene1066 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01067 S100141_01068 S100141_01068 S100141_01068 957709 957897 + uncharacterized protein Coiled coil. gene gene1067 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01068 S100141_01069 S100141_01069 impA impA 958039 958833 + Inositol-phosphate phosphatase Hydrolase%3B Magnesium%3B Metal-binding%3B Belongs to the inositol monophosphatase family%3B KEGG: bli:BL05151 myo-inositol-1(or 4)-monophosphatase gene gene1068 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01069 S100141_01070 S100141_01070 S100141_01070 958898 959293 + uncharacterized protein Contains 1 N-acetyltransferase domain gene gene1069 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01070 S100141_01071 S100141_01071 S100141_01071 959401 961326 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B overlaps another CDS with the same product name gene gene1070 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01071 S100141_01072 S100141_01072 S100141_01072 961316 961570 + uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix%3B overlaps another CDS with the same product name gene gene1071 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01072 S100141_01073 S100141_01073 S100141_01073 961591 962106 + RNA polymerase sigma factor YlaC DNA-binding%3B Sigma factor%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor contributes to oxidative stress resistance%3B Belongs to the sigma-70 factor family. ECF subfamily gene gene1072 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01073 S100141_01074 S100141_01074 S100141_01074 962111 962407 + Anti-sigma-YlaC factor YlaD Cell membrane%3B Membrane%3B Metal-binding%3B Transmembrane%3B Transmembrane helix%3B Zinc%3B Anti-sigma factor for YlaC%3B Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily gene gene1073 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01074 S100141_01075 S100141_01075 S100141_01075 962481 962669 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1074 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01075 S100141_01076 S100141_01076 S100141_01076 962831 964669 + GTP-binding protein TypA/BipA like protein GTP-binding%3B Nucleotide-binding%3B Not know%3B probably interacts with the ribosomes in a GTP dependent manner%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. TypA subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene1075 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01076 S100141_01077 S100141_01077 S100141_01077 964727 965047 + putative membrane protein YlaH Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1076 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01077 S100141_01078 S100141_01078 S100141_01078 965069 965575 - putative HTH-type transcriptional regulator YhjH Cytoplasm%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH marR-type DNA-binding domain gene gene1077 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01078 S100141_01079 S100141_01079 mhpA mhpA 965664 967145 - 3-(3-hydroxy-phenyl)propanoic acid hydroxylase Antibiotic biosynthesis%3B FAD%3B Flavoprotein%3B NADP%3B Oxidoreductase%3B Catalyzes hydroxylation of the anthracycline structure at position C-6 during the biosynthesis of oxytetracyline%3B Belongs to the PheA/TfdB FAD monooxygenase family%3B KEGG: mxa:MXAN_1594 3-(3-hydroxy-phenyl)propionate hydroxylase gene gene1078 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01079 S100141_01080 S100141_01080 S100141_01080 967284 967490 - uncharacterized protein gene gene1079 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01080 S100141_01081 S100141_01081 S100141_01081 967611 968225 - putative lipoprotein YlaJ Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal. gene gene1080 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01081 S100141_01082 S100141_01082 S100141_01082 968381 969709 + uncharacterized protein ATP-binding%3B Nucleotide-binding%3B In the C-terminal sectio%3B belongs to the PhoH family%3B Contains 1 PINc domain gene gene1081 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01082 S100141_01083 S100141_01083 S100141_01083 969853 970335 - uncharacterized protein gene gene1082 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01083 S100141_01084 S100141_01084 glsA glsA 970454 971383 + Glutaminase Hydrolase%3B Belongs to the glutaminase family%3B KEGG: bsr:I33_1665 glutaminase gene gene1083 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01084 S100141_01085 S100141_01085 S100141_01085 971516 971797 + UPF0358 protein Belongs to the UPF0358 family gene gene1084 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01085 S100141_01086 S100141_01086 S100141_01086 972128 973339 + Putative lipid II flippase FtsW Cell cycle%3B Cell division%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Peptidoglycan synthesis%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Essential cell division protein (Probable). Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane (By similarity)%3B Belongs to the SEDS family. FtsW subfamily gene gene1085 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01086 S100141_01087 S100141_01087 S100141_01087 973418 976861 + Pyruvate carboxylase ATP-binding%3B Biotin%3B Ligase%3B Metal-binding%3B Multifunctional enzyme%3B Nucleotide-binding%3B Catalyzes a 2-step reaction%2C involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second%2C leading to oxaloacetate production. Fulfills an anaplerotic function in B. subtilis as it is necessary for growth on glucose%2C but is not required for sporulation%3B Contains 1 ATP-grasp domain%3B Contains 1 biotin carboxylation domain%3B Contains 1 biotinyl-binding domain%3B Contains 1 carboxyltransferase domain%3B KEGG: bsu:BSU14860 pyruvate carboxylase gene gene1086 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01087 S100141_01088 S100141_01088 S100141_01088 976943 977851 - Heme A synthase Cell membrane%3B Heme biosynthesis%3B Membrane%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group%3B Belongs to the COX15/CtaA family. Type 1 subfamily gene gene1087 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01088 S100141_01089 S100141_01089 cyoE cyoE 978253 979179 + Protoheme IX farnesyltransferase Cell membrane%3B Heme biosynthesis%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group%3B Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily%3B KEGG: bli:BL02979 protoheme IX farnesyltransferase%3B Transferring alkyl or aryl groups%2C other than methyl groups gene gene1088 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01089 S100141_01090 S100141_01090 coxB coxB 979457 980524 + Cytochrome-c oxidase Cell membrane%3B Copper%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Respiratory chain%3B Signal%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). Belongs to the cytochrome c oxidase subunit 2 family%3B Contains 1 cytochrome c domain%3B KEGG: bli:BL02980 cytochrome c oxidase subunit II gene gene1089 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01090 S100141_01091 S100141_01091 coxA coxA 980557 982425 + Cytochrome-c oxidase Cell membrane%3B Copper%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Respiratory chain%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme a of subunit 1 to the bimetallic center formed by heme a3 and copper B. This cytochrome c oxidase shows proton pump activity across the membrane in addition to the electron transfer. Belongs to the heme-copper respiratory oxidase family%3B KEGG: bli:BL02981 cytochrome c oxidase subunit I%3B overlaps another CDS with the same product name gene gene1090 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01091 S100141_01092 S100141_01092 coxC coxC 982425 983048 + Cytochrome-c oxidase Cell membrane%3B Membrane%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Belongs to the cytochrome c oxidase subunit 3 family%3B KEGG: bli:BL02982 cytochrome c oxidase subunit III%3B overlaps another CDS with the same product name gene gene1091 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01092 S100141_01093 S100141_01093 coxD coxD 983051 983380 + Cytochrome-c oxidase Cell membrane%3B Membrane%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Belongs to the cytochrome c oxidase bacterial subunit 4 family%3B KEGG: bli:BL02983 cytochrome c oxidase subunit IV gene gene1092 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01093 S100141_01094 S100141_01094 S100141_01094 983411 984313 + Protein CtaG Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1093 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01094 S100141_01095 S100141_01095 S100141_01095 984370 984729 - uncharacterized protein gene gene1094 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01095 S100141_01096 S100141_01096 S100141_01096 984897 985343 + uncharacterized protein CBS domain%3B Repeat%3B Contains 2 CBS domains gene gene1095 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01096 S100141_01097 S100141_01097 S100141_01097 985484 986527 + putative membrane protein YlbC Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Contains 1 SCP domain gene gene1096 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01097 S100141_01098 S100141_01098 S100141_01098 986681 987076 + uncharacterized protein gene gene1097 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01098 S100141_01099 S100141_01099 S100141_01099 987091 987330 + uncharacterized protein gene gene1098 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01099 S100141_01100 S100141_01100 S100141_01100 987408 987539 + hypothetical protein gene gene1099 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01100 S100141_01101 S100141_01101 S100141_01101 987609 988058 + Regulatory protein YlbF Competence%3B Cytoplasm%3B Sporulation%3B Regulates sporulation prior to stage II. Positively controls the competence regulator ComK at a post-transcriptional level. May modulate the translation%2C stability or activity of ComS. May work together with YmcA to regulate community development gene gene1100 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01101 S100141_01102 S100141_01102 S100141_01102 988058 988402 + UPF0298 protein Cytoplasm%3B Belongs to the UPF0298 family gene gene1101 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01102 S100141_01103 S100141_01103 S100141_01103 988512 988646 + hypothetical protein gene gene1102 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01103 S100141_01104 S100141_01104 rsmD rsmD 988701 989261 + 16S rRNA (guanine(966)-N(2))-methyltransferase Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B May catalyze the S-adenosyl-L-methionine-dependent methylation of a specific base in rRNA%3B Belongs to the methyltransferase superfamily. RsmD family%3B KEGG: vsp:VS_3023 16S rRNA (guanine966-N2)-methyltransferase gene gene1103 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01104 S100141_01105 S100141_01105 coaD coaD 989254 989748 + Pantetheine-phosphate adenylyltransferase ATP-binding%3B Coenzyme A biosynthesis%3B Cytoplasm%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase%3B Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine%2C yielding dephospho-CoA (dPCoA) and pyrophosphate%3B Belongs to the bacterial CoaD family%3B KEGG: bsu:BSU15020 pantetheine-phosphate adenylyltransferase gene gene1104 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01105 S100141_01106 S100141_01106 S100141_01106 989757 990977 - Sporulation integral membrane protein YlbJ Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Required for spore cortex formation gene gene1105 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01106 S100141_01107 S100141_01107 S100141_01107 991301 992323 + uncharacterized protein Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Serine protease%3B Transmembrane%3B Transmembrane helix%3B Contains 1 PDZ (DHR) domain gene gene1106 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01107 S100141_01108 S100141_01108 S100141_01108 992340 993590 - UPF0348 protein Belongs to the UPF0348 family gene gene1107 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01108 S100141_01109 S100141_01109 S100141_01109 993808 994323 + uncharacterized protein gene gene1108 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01109 S100141_01110 S100141_01110 S100141_01110 994347 994520 + 50S ribosomal protein L32-2 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L32P family gene gene1109 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01110 S100141_01111 S100141_01111 S100141_01111 994675 995274 + uncharacterized protein DNA-binding%3B Contains 1 HTH myb-type DNA-binding domain gene gene1110 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01111 S100141_01112 S100141_01112 S100141_01112 995317 995796 - putative N-acetyltransferase Acyltransferase%3B Transferase%3B Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK3680 null%3B Transferring groups other than amino-acyl groups gene gene1111 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01112 S100141_01113 S100141_01113 panE panE 995979 996860 + 2-dehydropantoate 2-reductase Cytoplasm%3B NADP%3B Oxidoreductase%3B Pantothenate biosynthesis%3B Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid%3B Belongs to the ketopantoate reductase family%3B KEGG: bsu:BSU15110 2-dehydropantoate 2-reductase gene gene1112 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01113 S100141_01114 S100141_01114 S100141_01114 996945 998561 + Putative cysteine ligase BshC Coiled coil%3B Ligase%3B Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway%2C the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH%3B Belongs to the BshC family gene gene1113 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01114 S100141_01115 S100141_01115 S100141_01115 998672 999118 + Transcriptional regulator MraZ Cytoplasm%3B DNA-binding%3B Repeat%3B Transcription%3B Transcription regulation%3B Belongs to the MraZ family%3B Contains 2 SpoVT-AbrB domains gene gene1114 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01115 S100141_01116 S100141_01116 mraW mraW 999118 1000122 + 16S rRNA (cytosine(1402)-N(4))-methyltransferase Cytoplasm%3B Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA%3B Belongs to the methyltransferase superfamily. RsmH family%3B KEGG: pca:Pcar_2210 16S rRNA (cytosine1402-N4)-methyltransferase gene gene1115 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01116 S100141_01117 S100141_01117 S100141_01117 1000154 1000507 + Cell division protein FtsL Cell cycle%3B Cell division%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Essential cell division protein%3B Belongs to the FtsL family gene gene1116 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01117 S100141_01118 S100141_01118 S100141_01118 1000514 1002649 + Penicillin-binding protein 2B Antibiotic resistance%3B Cell cycle%3B Cell division%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Peptidoglycan synthesis%3B Repeat%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis. PBP-2B is required for vegetative cell division and sporulation septation. Beta-lactamase inactivates the PBPs by acylating an essential serine residue in the active site of these proteins%2C thereby interrupting normal cell wall synthesis. Belongs to the transpeptidase family%3B Contains 2 PASTA domains gene gene1117 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01118 S100141_01119 S100141_01119 S100141_01119 1002792 1004726 + Stage V sporulation protein D Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Peptidoglycan synthesis%3B Sporulation%3B Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex%2C which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell. Belongs to the transpeptidase family%3B Contains 1 PASTA domain gene gene1118 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01119 S100141_01120 S100141_01120 S100141_01120 1004758 1004898 + hypothetical protein gene gene1119 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01120 S100141_01121 S100141_01121 murE murE 1004922 1006388 + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2%2C6-diaminopimelate ligase ATP-binding%3B Cell cycle%3B Cell division%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Ligase%3B Magnesium%3B Nucleotide-binding%3B Peptidoglycan synthesis%3B Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan%3B Belongs to the MurCDEF family. MurE subfamily%3B KEGG: bsu:BSU15180 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2%2C6-diaminopimelate ligase gene gene1120 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01121 S100141_01122 S100141_01122 mraY mraY 1006516 1007490 + Phospho-N-acetylmuramoyl-pentapeptide-transferase Cell cycle%3B Cell division%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Peptidoglycan synthesis%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan%3B Belongs to the glycosyltransferase 4 family. MraY subfamily%3B KEGG: bsu:BSU15190 phospho-N-acetylmuramoyl-pentapeptide-transferase gene gene1121 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01122 S100141_01123 S100141_01123 murD murD 1007491 1008846 + UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase ATP-binding%3B Cell cycle%3B Cell division%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Peptidoglycan synthesis%3B Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)%3B Belongs to the MurCDEF family%3B KEGG: bli:BL02241 UDP-N-acetylmuramoylalanine--D-glutamate ligase gene gene1122 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01123 S100141_01124 S100141_01124 S100141_01124 1008929 1009999 + Putative lipid II flippase FtsW Cell cycle%3B Cell division%3B Cell inner membrane%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Peptidoglycan synthesis%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Essential cell division protein. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane%3B Belongs to the SEDS family. FtsW subfamily gene gene1123 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01124 S100141_01125 S100141_01125 murG murG 1010071 1011171 + Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase Cell cycle%3B Cell division%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Glycosyltransferase%3B Membrane%3B Peptidoglycan synthesis%3B Transferase%3B Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)%3B Belongs to the glycosyltransferase 28 family. MurG subfamily%3B KEGG: gsu:GSU3069 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase gene gene1124 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01125 S100141_01126 S100141_01126 murB murB 1011200 1012111 + UDP-N-acetylmuramate dehydrogenase Cell cycle%3B Cell division%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B FAD%3B Flavoprotein%3B NADP%3B Oxidoreductase%3B Peptidoglycan synthesis%3B Cell wall formation%3B Belongs to the MurB family%3B Contains 1 FAD-binding PCMH-type domain%3B KEGG: bsu:BSU15230 UDP-N-acetylmuramate dehydrogenase gene gene1125 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01126 S100141_01127 S100141_01127 S100141_01127 1012317 1013105 + Cell division protein DivIB Cell cycle%3B Cell division%3B Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex. Plays an essential role in division at high temperatures%2C maybe by protecting FtsL from degradation or by promoting formation of the FtsL-DivIC complex. May modulate the transpeptidase activity of PBP-2B. Also required for efficient sporulation at all temperatures. Could be directly involved in the engulfment process or be required to form a sporulation septum competent for engulfment. Influences the Spo0J/Soj system of chromosome segregation%3B Belongs to the FtsQ/DivIB family. DivIB subfamily%3B Contains 1 POTRA domain gene gene1126 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01127 S100141_01128 S100141_01128 S100141_01128 1013102 1013794 + UPF0749 protein YlxW Cell cycle%3B Cell division%3B Coiled coil%3B Signal%3B Sporulation%3B May be involved in cell division and sporulation%3B Belongs to the UPF0749 family gene gene1127 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01128 S100141_01129 S100141_01129 S100141_01129 1013820 1014545 + UPF0749 protein YlxX Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0749 family gene gene1128 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01129 S100141_01130 S100141_01130 S100141_01130 1014545 1014898 + Small basic protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the sbp family gene gene1129 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01130 S100141_01131 S100141_01131 S100141_01131 1015082 1016380 + Cell division protein FtsA Cell cycle%3B Cell division%3B Cell membrane%3B Cell shape%3B Membrane%3B Sporulation%3B Cell division protein that is required for the assembly of the Z ring (PubMed:16159787). May serve as a membrane anchor for the Z ring (By similarity). Binds and hydrolyzes ATP (PubMed:11298280). Also involved in sporulation (Probable)%3B Belongs to the FtsA/MreB family gene gene1130 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01131 S100141_01132 S100141_01132 S100141_01132 1016415 1017548 + Cell division protein FtsZ Cell cycle%3B Cell division%3B Cytoplasm%3B GTP-binding%3B Nucleotide-binding%3B Septation%3B Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity%3B Belongs to the FtsZ family gene gene1131 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01132 S100141_01133 S100141_01133 S100141_01133 1017928 1019436 + Bacillopeptidase Hydrolase%3B Protease%3B Secreted%3B Serine protease%3B Signal%3B Zymogen%3B Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: blh:BaLi_c17820 bacillopeptidase F%3B Serine endopeptidases gene gene1132 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01133 S100141_01134 S100141_01134 S100141_01134 1019476 1020906 - hypothetical protein gene gene1133 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01134 S100141_01135 S100141_01135 S100141_01135 1021188 1023071 + Bacillopeptidase Hydrolase%3B Protease%3B Secreted%3B Serine protease%3B Signal%3B Zymogen%3B Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bli:BL02253 bacillopeptidase F%3B Serine endopeptidases%3B overlaps another CDS with the same product name gene gene1134 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01135 S100141_01136 S100141_01136 S100141_01136 1023068 1025485 + Bacillopeptidase Hydrolase%3B Protease%3B Secreted%3B Serine protease%3B Signal%3B Zymogen%3B Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bli:BL02253 bacillopeptidase F%3B Serine endopeptidases%3B overlaps another CDS with the same product name gene gene1135 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01136 S100141_01137 S100141_01137 S100141_01137 1025587 1026597 + Sporulation sigma-E factor-processing peptidase Aspartyl protease%3B Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR (By similarity)%3B Belongs to the peptidase U4 family%3B KEGG: bli:BL02254 stage II sporulation protein GA (sporulation sigma-E factor processing peptidase)%3B Aspartic endopeptidases gene gene1136 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01137 S100141_01138 S100141_01138 S100141_01138 1026657 1027376 + RNA polymerase sigma-E factor DNA-binding%3B Sigma factor%3B Sporulation%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes. Belongs to the sigma-70 factor family gene gene1137 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01138 S100141_01139 S100141_01139 S100141_01139 1027516 1028295 + RNA polymerase sigma-G factor DNA-binding%3B Sigma factor%3B Sporulation%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the forespore. Belongs to the sigma-70 factor family gene gene1138 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01139 S100141_01140 S100141_01140 S100141_01140 1028431 1029120 + Iron-chelate-transporting ATPase ATP-binding%3B Hydrolase%3B Nucleotide-binding%3B Transport%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: fau:Fraau_2706 iron complex transport system ATP-binding protein gene gene1139 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01140 S100141_01141 S100141_01141 S100141_01141 1029495 1030382 + 23S rRNA (guanine(745)-N(1))-methyltransferase Metal-binding%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Zinc%3B Belongs to the methyltransferase superfamily. RlmA family%3B KEGG: blh:BaLi_c17880 23S rRNA (guanine745-N1)-methyltransferase gene gene1140 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01141 S100141_01142 S100141_01142 S100141_01142 1030467 1030700 + uncharacterized protein Belongs to the YlmC/YmxH family gene gene1141 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01142 S100141_01143 S100141_01143 S100141_01143 1030924 1031763 + Laccase domain protein YlmD Belongs to the LACC1 family gene gene1142 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01143 S100141_01144 S100141_01144 S100141_01144 1031771 1032466 + UPF0001 protein YlmE Pyridoxal phosphate%3B Belongs to the UPF0001 family gene gene1143 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01144 S100141_01145 S100141_01145 S100141_01145 1032463 1032915 + Cell division protein SepF Cell cycle%3B Cell division%3B Cytoplasm%3B Septation%3B Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation%2C perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA%3B Belongs to the SepF family gene gene1144 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01145 S100141_01146 S100141_01146 S100141_01146 1032923 1033192 + putative membrane protein YlmG Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the YggT family gene gene1145 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01146 S100141_01147 S100141_01147 S100141_01147 1033328 1034104 + Putative RNA-binding protein YlmH RNA-binding%3B Contains 1 S4 RNA-binding domain gene gene1146 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01147 S100141_01148 S100141_01148 S100141_01148 1034200 1034694 + Septum site-determining protein DivIVA Cell cycle%3B Cell division%3B Coiled coil%3B Cytoplasm%3B Septation%3B Sporulation%3B May act as a pilot protein%2C directing MinCD to the polar septation sites or by inhibiting MinCD at the midcell site of division. Required for polar localization of the chromosome during sporulation%3B Belongs to the DivIVA family gene gene1147 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01148 S100141_01149 S100141_01149 iarS iarS 1035038 1037806 + Isoleucine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B Zinc%3B Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine%2C to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)%3B Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily%3B KEGG: hhe:HH1190 isoleucyl-tRNA synthetase gene gene1148 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01149 S100141_01150 S100141_01150 S100141_01150 1038070 1038435 + uncharacterized protein Metal-binding%3B Zinc%3B Zinc-finger%3B Contains 1 dksA C4-type zinc finger gene gene1149 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01150 S100141_01151 S100141_01151 lspA lspA 1038480 1039019 + Signal peptidase II Aspartyl protease%3B Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Transmembrane%3B Transmembrane helix%3B This protein specifically catalyzes the removal of signal peptides from prolipoproteins%3B Belongs to the peptidase A8 family%3B KEGG: blh:BaLi_c17980 signal peptidase II gene gene1150 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01151 S100141_01152 S100141_01152 S100141_01152 1039021 1039935 + 23S rRNA pseudouridine(1911/1915/1917) synthase Isomerase%3B RNA-binding%3B Belongs to the pseudouridine synthase RluA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: bli:BL02270 23S rRNA pseudouridine1911/1915/1917 synthase gene gene1151 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01152 S100141_01153 S100141_01153 pyrR pyrR 1040113 1040661 + Uracil phosphoribosyltransferase Glycosyltransferase%3B RNA-binding%3B Transcription%3B Transcription regulation%3B Transcription termination%3B Transferase%3B Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator%2C leading to a reduced expression of downstream genes%3B Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant%3B Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily%3B KEGG: bli:BL02271 pyrimidine operon attenuation protein / uracil phosphoribosyltransferase gene gene1152 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01153 S100141_01154 S100141_01154 S100141_01154 1040856 1042160 + Uracil permease Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Transport of uracil in the cell. Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2. A. 40) subfamily gene gene1153 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01154 S100141_01155 S100141_01155 pyrB pyrB 1042304 1043224 + Aspartate carbamoyltransferase Pyrimidine biosynthesis%3B Transferase%3B Belongs to the ATCase/OTCase family%3B KEGG: bli:BL02273 aspartate carbamoyltransferase catalytic subunit gene gene1154 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01155 S100141_01156 S100141_01156 S100141_01156 1043208 1044494 + Dihydroorotase Hydrolase%3B Metal-binding%3B Pyrimidine biosynthesis%3B Zinc%3B Belongs to the DHOase family. Type 2 subfamily%3B KEGG: bsu:BSU15500 dihydroorotase gene gene1155 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01156 S100141_01157 S100141_01157 S100141_01157 1044491 1045585 + Carbamoyl-phosphate synthase (glutamine-hydrolyzing) ATP-binding%3B Glutamine amidotransferase%3B Ligase%3B Nucleotide-binding%3B Pyrimidine biosynthesis%3B Belongs to the CarA family%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: bsu:BSU15510 carbamoyl-phosphate synthase small subunit%3B overlaps another CDS with the same product name gene gene1156 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01157 S100141_01158 S100141_01158 S100141_01158 1045570 1048782 + Carbamoyl-phosphate synthase (glutamine-hydrolyzing) Amino-acid biosynthesis%3B Arginine biosynthesis%3B ATP-binding%3B Ligase%3B Magnesium%3B Manganese%3B Metal-binding%3B Nucleotide-binding%3B Pyrimidine biosynthesis%3B Repeat%3B Belongs to the CarB family%3B Contains 2 ATP-grasp domains%3B KEGG: har:HEAR1165 carbamoyl-phosphate synthase large subunit%3B overlaps another CDS with the same product name gene gene1157 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01158 S100141_01159 S100141_01159 S100141_01159 1048779 1049549 + Dihydroorotate dehydrogenase B (NAD(+))%2C electron transfer subunit 2Fe-2S%3B Electron transport%3B FAD%3B Flavoprotein%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Pyrimidine biosynthesis%3B Transport%3B Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+)%3B Belongs to the PyrK family%3B Contains 1 FAD-binding FR-type domain gene gene1158 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01159 S100141_01160 S100141_01160 S100141_01160 1049546 1050484 + Dihydroorotate dehydrogenase (NAD(+)) Cytoplasm%3B Flavoprotein%3B FMN%3B NAD%3B Oxidoreductase%3B Pyrimidine biosynthesis%3B Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor%3B Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily%3B KEGG: bld:BLi01774 dihydroorotate dehydrogenase (NAD+) catalytic subunit gene gene1159 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01160 S100141_01161 S100141_01161 pyrF pyrF 1050453 1051172 + Orotidine-5'-phosphate decarboxylase Decarboxylase%3B Lyase%3B Pyrimidine biosynthesis%3B Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)%3B Belongs to the OMP decarboxylase family. Type 1 subfamily%3B KEGG: eco:b1281 orotidine-5'-phosphate decarboxylase gene gene1160 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01161 S100141_01162 S100141_01162 pyrE pyrE 1051169 1051798 + Orotate phosphoribosyltransferase Glycosyltransferase%3B Magnesium%3B Pyrimidine biosynthesis%3B Transferase%3B Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate%2C leading to the formation of orotidine monophosphate (OMP)%3B Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily%3B KEGG: bli:BL02280 orotate phosphoribosyltransferase gene gene1161 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01162 S100141_01163 S100141_01163 S100141_01163 1052144 1052287 + hypothetical protein gene gene1162 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01163 S100141_01164 S100141_01164 cysH cysH 1052534 1053076 + Phosphoadenylyl-sulfate reductase (thioredoxin) Cytoplasm%3B Oxidoreductase%3B Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily%3B KEGG: bsu:BSU15570 phosphoadenosine phosphosulfate reductase gene gene1163 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01164 S100141_01165 S100141_01165 S100141_01165 1053088 1054152 + Sulfate permease CysP Cell membrane%3B Membrane%3B Sulfate transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the import of sulfate%3B Belongs to the inorganic phosphate transporter (PiT) (TC 2. A. 20) family gene gene1164 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01165 S100141_01166 S100141_01166 met3 met3 1054178 1055314 + Sulfate adenylyltransferase ATP-binding%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase%3B Belongs to the sulfate adenylyltransferase family%3B KEGG: bsu:BSU15590 sulfate adenylyltransferase gene gene1165 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01166 S100141_01167 S100141_01167 cysC cysC 1055328 1055921 + Adenylyl-sulfate kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Catalyzes the synthesis of activated sulfate%3B Belongs to the APS kinase family%3B KEGG: sun:SUN_1719 adenylylsulfate kinase gene gene1166 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01167 S100141_01168 S100141_01168 cobA cobA 1056073 1056846 + Uroporphyrinogen-III C-methyltransferase Cobalamin biosynthesis%3B Methyltransferase%3B Porphyrin biosynthesis%3B S-adenosyl-L-methionine%3B Transferase%3B Catalyzes both methylations at C-2 and C-7 of uroporphyrinogen III leading to precorrin-1 and precorrin-%3B their oxidative esterification gives respectively factor I octamethyl ester and sirohydrochlorin. Belongs to the precorrin methyltransferase family%3B KEGG: shl:Shal_3534 uroporphyrin-III C-methyltransferase gene gene1167 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01168 S100141_01169 S100141_01169 sirB sirB 1056848 1057633 + Sirohydrochlorin ferrochelatase Iron%3B Lyase%3B Metal-binding%3B Porphyrin biosynthesis%3B Chelates iron to the siroheme precursor%3B Belongs to the CbiX family. SirB subfamily%3B KEGG: bsu:BSU15620 sirohydrochlorin ferrochelatase gene gene1168 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01169 S100141_01170 S100141_01170 met8 met8 1057614 1058108 + Precorrin-2 dehydrogenase Cobalamin biosynthesis%3B Lyase%3B Methyltransferase%3B Multifunctional enzyme%3B NAD%3B Oxidoreductase%3B Phosphoprotein%3B Porphyrin biosynthesis%3B S-adenosyl-L-methionine%3B Transferase%3B Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally%2C it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme%3B In the N-terminal sectio%3B belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family%3B In the C-terminal sectio%3B belongs to the precorrin methyltransferase family%3B KEGG: bli:BL02289 precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase gene gene1169 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01170 S100141_01171 S100141_01171 S100141_01171 1058129 1059841 - uncharacterized protein Coiled coil%3B Belongs to the NEMF family gene gene1170 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01171 S100141_01172 S100141_01172 S100141_01172 1059988 1062660 + Calcium-transporting ATPase ATP-binding%3B Calcium%3B Calcium transport%3B Cell membrane%3B Hydrolase%3B Ion transport%3B Magnesium%3B Membrane%3B Metal-binding%3B Nucleotide-binding%3B Phosphoprotein%3B Transmembrane%3B Transmembrane helix%3B Transport%3B This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium%3B Belongs to the cation transport ATPase (P-type) (TC 3. A. 3) family. Type IIA subfamily%3B KEGG: bsu:BSU15650 Ca2+-transporting ATPase gene gene1171 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01172 S100141_01173 S100141_01173 S100141_01173 1062762 1063646 + UPF0701 protein YloC Belongs to the UPF0701 family gene gene1172 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01173 S100141_01174 S100141_01174 S100141_01174 1063722 1063991 + UPF0296 protein Belongs to the UPF0296 family gene gene1173 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01174 S100141_01175 S100141_01175 S100141_01175 1063999 1064613 + Guanylate kinase ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Essential for recycling GMP and indirectly%2C cGMP%3B Belongs to the guanylate kinase family%3B Contains 1 guanylate kinase-like domain%3B KEGG: bsu:BSU15680 guanylate kinase gene gene1174 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01175 S100141_01176 S100141_01176 rpoZ rpoZ 1064616 1064816 + DNA-directed RNA polymerase DNA-directed RNA polymerase%3B Nucleotidyltransferase%3B Transcription%3B Transferase%3B Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits%3B Belongs to the RNA polymerase subunit omega family%3B KEGG: bsu:BSU15690 DNA-directed RNA polymerase subunit omega gene gene1175 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01176 S100141_01177 S100141_01177 S100141_01177 1064898 1066115 + Phosphopantothenoylcysteine decarboxylase Decarboxylase%3B Flavoprotein%3B FMN%3B Ligase%3B Lyase%3B Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine%2C in the latter compound is decarboxylated to form 4'-phosphopantotheine (By similarity)%3B In the N-terminal sectio%3B belongs to the HFCD (homo- oligomeric flavin containing Cys decarboxylase) superfamily%3B In the C-terminal sectio%3B belongs to the PPC synthetase family%3B KEGG: hpaz:K756_08760 phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase gene gene1176 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01177 S100141_01178 S100141_01178 priA priA 1066112 1068529 + Primosomal protein N' ATP-binding%3B DNA replication%3B DNA-binding%3B Helicase%3B Hydrolase%3B Metal-binding%3B Nucleotide-binding%3B Primosome%3B Zinc%3B Zinc-finger%3B Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex%2C via its helicase activity%2C and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA%3B Belongs to the helicase family. PriA subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bsu:BSU15710 primosomal protein N' (replication factor Y) (superfamily II helicase)%3B Acting on ATP%3B involved in cellular and subcellular movement gene gene1177 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01178 S100141_01179 S100141_01179 S100141_01179 1068559 1069041 + Peptide deformylase Hydrolase%3B Iron%3B Metal-binding%3B Protein biosynthesis%3B Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions%3B Belongs to the polypeptide deformylase family%3B KEGG: mes:Meso_0394 peptide deformylase gene gene1178 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01179 S100141_01180 S100141_01180 S100141_01180 1069046 1069996 + Methionyl-tRNA formyltransferase Protein biosynthesis%3B Transferase%3B Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by: (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP%3B Belongs to the Fmt family%3B KEGG: caj:CIG1485E_1484 methionyl-tRNA formyltransferase gene gene1179 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01180 S100141_01181 S100141_01181 rsmB rsmB 1069980 1071332 + 16S rRNA (cytosine(967)-C(5))-methyltransferase Cytoplasm%3B Methyltransferase%3B Ribosome biogenesis%3B RNA-binding%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family%3B KEGG: bli:BL02299 16S rRNA (cytosine967-C5)-methyltransferase gene gene1180 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01181 S100141_01182 S100141_01182 rlmN rlmN 1071332 1072417 + 23S rRNA (adenine(2503)-C(2))-methyltransferase 4Fe-4S%3B Cytoplasm%3B Disulfide bond%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B tRNA processing%3B Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs%3B Belongs to the radical SAM superfamily. RlmN family%3B KEGG: bli:BL02300 23S rRNA (adenine2503-C2)-methyltransferase gene gene1181 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01182 S100141_01183 S100141_01183 S100141_01183 1072425 1073189 + Protein-serine/threonine phosphatase Hydrolase%3B Manganese%3B Metal-binding%3B Protein phosphatase%3B Sporulation%3B Protein phosphatase that dephosphorylates PrkC and FusA (elongation factor G). PrpC and prkC are cotranscribed%2C which suggests that they form a functional couple in vivo%2C PrpC's primary role being possibly to counter the action of PrkC. May be involved in sporulation and biofilm formation. Does not seem to be involved in stress response%3B Contains 1 PPM-type phosphatase domain%3B KEGG: bsu:BSU15760 protein phosphatase gene gene1182 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01183 S100141_01184 S100141_01184 S100141_01184 1073183 1075156 + Non-specific serine/threonine protein kinase ATP-binding%3B Germination%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Repeat%3B Serine/threonine-protein kinase%3B Signal-anchor%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Protein kinase that is responsible for triggering spore germination in response to muropeptides%2C signaling bacteria to exit dormancy. Autophosphorylates and phosphorylates FusA (EF-G%2C elongation factor G%3B the latter modification is likely necessary for germination in response to peptidoglycan. PrkC is a substrate in vitro of the cotranscribed phosphatase PrpC%2C which suggests that they form a functional couple in vivo. Might also be involved in sporulation and biofilm formation. Does not seem to be involved in stress response%3B Belongs to the protein kinase superfamily. Ser/Thr protein kinase family%3B Contains 3 PASTA domains%3B Contains 1 protein kinase domain%3B KEGG: bsu:BSU15770 serine/threonine protein kinase%2C bacterial gene gene1183 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01184 S100141_01185 S100141_01185 S100141_01185 1075169 1076053 + Putative ribosome bioproteinis GTPase RsgA GTP-binding%3B Hydrolase%3B Metal-binding%3B Nucleotide-binding%3B Zinc%3B May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover%3B Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily%3B Contains 1 CP-type G (guanine nucleotide-binding) domain%3B KEGG: bli:BL02304 ribosome biogenesis GTPase%3B In phosphorus-containing anhydrides gene gene1184 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01185 S100141_01186 S100141_01186 S100141_01186 1076057 1076713 + Ribulose-phosphate 3-epimerase Calvin cycle%3B Carbohydrate metabolism%3B Cobalt%3B Iron%3B Isomerase%3B Manganese%3B Metal-binding%3B Zinc%3B Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate%3B Belongs to the ribulose-phosphate 3-epimerase family%3B KEGG: cjm:CJM1_0433 ribulose-phosphate 3-epimerase gene gene1185 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01186 S100141_01187 S100141_01187 thiN thiN 1076789 1077433 + Thiamine diphosphokinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate. Belongs to the thiamine pyrophosphokinase family%3B KEGG: bsu:BSU15800 thiamine pyrophosphokinase gene gene1186 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01187 S100141_01188 S100141_01188 S100141_01188 1077704 1077892 - 50S ribosomal protein L28 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L28P family gene gene1187 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01188 S100141_01189 S100141_01189 S100141_01189 1078180 1078542 + uncharacterized protein Belongs to the asp23 family gene gene1188 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01189 S100141_01190 S100141_01190 S100141_01190 1078560 1080230 + uncharacterized protein Contains 1 DhaL domain gene gene1189 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01190 S100141_01191 S100141_01191 sdaA sdaA 1080404 1081066 + L-serine ammonia-lyase 4Fe-4S%3B Gluconeogenesis%3B Iron%3B Iron-sulfur%3B Lyase%3B Metal-binding%3B Belongs to the iron-sulfur dependent L-serine dehydratase family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU15850 L-serine dehydratase gene gene1190 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01191 S100141_01192 S100141_01192 S100141_01192 1081085 1081987 + L-serine ammonia-lyase 4Fe-4S%3B Gluconeogenesis%3B Iron%3B Iron-sulfur%3B Lyase%3B Metal-binding%3B Belongs to the iron-sulfur dependent L-serine dehydratase family%3B KEGG: bsu:BSU15860 L-serine dehydratase gene gene1191 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01192 S100141_01193 S100141_01193 recG recG 1081965 1084013 + DNA helicase ATP-binding%3B DNA damage%3B DNA recombination%3B DNA repair%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) (By similarity)%3B Belongs to the helicase family. RecG subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bli:BL02311 ATP-dependent DNA helicase RecG gene gene1192 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01193 S100141_01194 S100141_01194 S100141_01194 1084160 1084696 + Transcription factor FapR DNA-binding%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism%3B Belongs to the FapR family gene gene1193 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01194 S100141_01195 S100141_01195 plsX plsX 1084714 1085706 + Glycerol-3-phosphate 1-O-acyltransferase Cytoplasm%3B Lipid biosynthesis%3B Lipid metabolism%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor%2C but not acyl-CoA%3B Belongs to the PlsX family%3B KEGG: vfi:VF_1743 glycerol-3-phosphate acyltransferase PlsX gene gene1194 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01195 S100141_01196 S100141_01196 fabD fabD 1085724 1086683 + [Acyl-carrier-protein] S-malonyltransferase Acyltransferase%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Transferase%3B Belongs to the FabD family%3B KEGG: rah:Rahaq_2956 (acyl-carrier-protein) S-malonyltransferase gene gene1195 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01196 S100141_01197 S100141_01197 S100141_01197 1086670 1087413 + 3-oxoacyl-[acyl-carrier-protein] reductase Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B NADP%3B Oxidoreductase%3B Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products%2C the first reductive step in the elongation cycle of fatty acid biosynthesis%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: ahd:AI20_12755 3-oxoacyl-(acyl-carrier protein) reductase gene gene1196 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01197 S100141_01198 S100141_01198 S100141_01198 1087490 1087723 + Acyl carrier protein Cytoplasm%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Phosphopantetheine%3B Phosphoprotein%3B Carrier of the growing fatty acid chain in fatty acid biosynthesis%3B Contains 1 acyl carrier domain gene gene1197 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01198 S100141_01199 S100141_01199 rnt1 rnt1 1087865 1088614 + Ribonuclease III Cytoplasm%3B Endonuclease%3B Hydrolase%3B Magnesium%3B Metal-binding%3B mRNA processing%3B Nuclease%3B RNA-binding%3B rRNA processing%3B rRNA-binding%3B tRNA processing%3B Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs%2C and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism%3B Contains 1 DRBM (double-stranded RNA-binding) domain%3B Contains 1 RNase III domain%3B KEGG: bsu:BSU15930 ribonuclease III gene gene1198 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01199 S100141_01200 S100141_01200 S100141_01200 1088714 1092274 + Chromosome partition protein Smc ATP-binding%3B Coiled coil%3B Cytoplasm%3B DNA-binding%3B Nucleotide-binding%3B Required for chromosome condensation and partitioning%3B Belongs to the SMC family gene gene1199 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01200 S100141_01201 S100141_01201 S100141_01201 1092291 1093277 + Signal recognition particle receptor FtsY Cell membrane%3B Cytoplasm%3B GTP-binding%3B Membrane%3B Nucleotide-binding%3B Receptor%3B Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)%3B Belongs to the GTP-binding SRP family. FtsY subfamily gene gene1200 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01201 S100141_01202 S100141_01202 S100141_01202 1093411 1093734 + UPF0122 protein Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein%3B Belongs to the UPF0122 family gene gene1201 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01202 S100141_01203 S100141_01203 S100141_01203 1093750 1095090 + Signal recognition particle protein Cytoplasm%3B GTP-binding%3B Nucleotide-binding%3B Ribonucleoprotein%3B RNA-binding%3B Signal recognition particle%3B Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane%2C the hydrolysis of GTP by both Ffh and FtsY%2C and the dissociation of the SRP-FtsY complex into the individual components (Probable)%3B Belongs to the GTP-binding SRP family. SRP54 subfamily gene gene1202 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01203 S100141_01204 S100141_01204 S100141_01204 1095198 1095470 + 30S ribosomal protein S16 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein S16P family gene gene1203 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01204 S100141_01205 S100141_01205 S100141_01205 1095470 1095715 + UPF0109 protein YlqC RNA-binding%3B Belongs to the UPF0109 family%3B Contains 1 KH domain gene gene1204 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01205 S100141_01206 S100141_01206 S100141_01206 1095853 1096239 + uncharacterized protein gene gene1205 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01206 S100141_01207 S100141_01207 S100141_01207 1096244 1096768 + Ribosome maturation factor RimM Chaperone%3B Cytoplasm%3B Ribosome biogenesis%3B An accessory protein needed during the final step in the assembly of 30S ribosomal subunit%2C possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes%3B Belongs to the RimM family%3B Contains 1 PRC barrel domain gene gene1206 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01207 S100141_01208 S100141_01208 trmD trmD 1096765 1097496 + tRNA (guanine(37)-N(1))-methyltransferase Cytoplasm%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B tRNA processing%3B Specifically methylates guanosine-37 in various tRNAs%3B Belongs to the RNA methyltransferase TrmD family%3B KEGG: dno:DNO_1009 tRNA (guanine37-N1)-methyltransferase gene gene1207 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01208 S100141_01209 S100141_01209 S100141_01209 1097635 1097982 + 50S ribosomal protein L19 Ribonucleoprotein%3B Ribosomal protein%3B This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site%3B Belongs to the ribosomal protein L19P family gene gene1208 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01209 S100141_01210 S100141_01210 S100141_01210 1098097 1098948 + Ribosome bioproteinis GTPase Cytoplasm%3B GTP-binding%3B Hydrolase%3B Nucleotide-binding%3B Ribosome biogenesis%3B RNA-binding%3B Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity. Binds to the 23S rRNA (By similarity)%3B Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily%3B Contains 1 CP-type G (guanine nucleotide-binding) domain gene gene1209 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01210 S100141_01211 S100141_01211 rnhB rnhB 1099026 1099793 + Ribonuclease H Cytoplasm%3B Endonuclease%3B Hydrolase%3B Manganese%3B Metal-binding%3B Nuclease%3B Endonuclease that specifically degrades the RNA of RNA- DNA hybrids%3B Belongs to the RNase HII family%3B KEGG: bsu:BSU16060 ribonuclease HII gene gene1210 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01211 S100141_01212 S100141_01212 S100141_01212 1099809 1101506 + uncharacterized protein overlaps another CDS with the same product name gene gene1211 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01212 S100141_01213 S100141_01213 S100141_01213 1101503 1101784 + uncharacterized protein overlaps another CDS with the same product name gene gene1212 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01213 S100141_01214 S100141_01214 mtkA mtkA 1102029 1103120 + Malate--CoA ligase ATP-binding%3B Ligase%3B Magnesium%3B Manganese%3B Metal-binding%3B Nucleotide-binding%3B Phosphoprotein%3B Tricarboxylic acid cycle%3B Belongs to the succinate/malate CoA ligase beta subunit family%3B Contains 1 ATP-grasp domain%3B KEGG: mpt:Mpe_A3257 malate-CoA ligase subunit beta gene gene1213 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01214 S100141_01215 S100141_01215 mtkB mtkB 1103139 1104041 + Malate--CoA ligase ATP-binding%3B Ligase%3B Nucleotide-binding%3B Phosphoprotein%3B Tricarboxylic acid cycle%3B Belongs to the succinate/malate CoA ligase alpha subunit family%3B KEGG: mmt:Metme_2693 malate-CoA ligase subunit alpha gene gene1214 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01215 S100141_01216 S100141_01216 S100141_01216 1104155 1105057 + Protein smf Belongs to the smf family gene gene1215 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01216 S100141_01217 S100141_01217 topA topA 1105262 1107337 + DNA topoisomerase DNA-binding%3B Isomerase%3B Magnesium%3B Metal-binding%3B Repeat%3B Topoisomerase%3B Zinc%3B Zinc-finger%3B Releases the supercoiling and torsional tension of DNA%2C which is introduced during the DNA replication and transcription%2C by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme%2C resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand%2C thus removing DNA supercoils. Finally%2C in the religation step%2C the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone%3B Belongs to the type IA topoisomerase family%3B Contains 1 Toprim domain%3B KEGG: bsu:BSU16120 DNA topoisomerase I gene gene1216 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01217 S100141_01218 S100141_01218 S100141_01218 1107413 1108717 + Methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-methyltransferase(FADH(2)-oxidizing) Cytoplasm%3B FAD%3B Flavoprotein%3B Methyltransferase%3B Transferase%3B tRNA processing%3B Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs%3B Belongs to the MnmG family. TrmFO subfamily%3B KEGG: mor:MOC_1952 methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase gene gene1217 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01218 S100141_01219 S100141_01219 S100141_01219 1108784 1109698 + Tyrosine recombinase XerC Cell cycle%3B Cell division%3B Chromosome partition%3B Cytoplasm%3B DNA integration%3B DNA recombination%3B DNA-binding%3B Site-specific tyrosine recombinase%2C which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids%3B Belongs to the 'phage' integrase family. XerC subfamily gene gene1218 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01219 S100141_01220 S100141_01220 hslV hslV 1109712 1110257 + HslU--HslV peptidase Cytoplasm%3B Hydrolase%3B Metal-binding%3B Protease%3B Serine protease%3B Sodium%3B Protease subunit of a proteasome-like degradation complex%3B Belongs to the peptidase T1B family. HslV subfamily%3B KEGG: rhd:R2APBS1_3955 ATP-dependent HslUV protease%2C peptidase subunit HslV gene gene1219 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01220 S100141_01221 S100141_01221 S100141_01221 1110274 1111677 + ATP-dependent protease ATPase subunit ClpY ATP-binding%3B Chaperone%3B Cytoplasm%3B Nucleotide-binding%3B ATPase subunit of a proteasome-like degradation comple%3B this subunit has chaperone activity%3B Belongs to the ClpX chaperone family. HslU subfamily gene gene1220 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01221 S100141_01222 S100141_01222 S100141_01222 1111716 1112495 + GTP-sensing transcriptional pleiotropic repressor CodY Cytoplasm%3B DNA-binding%3B GTP-binding%3B Nucleotide-binding%3B Phosphoprotein%3B Repressor%3B Transcription%3B Transcription regulation%3B DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor%3B Belongs to the CodY family gene gene1221 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01222 S100141_01223 S100141_01223 S100141_01223 1112613 1112750 - hypothetical protein gene gene1222 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01223 S100141_01224 S100141_01224 S100141_01224 1112849 1113238 + Flagellar basal body rod protein FlgB Bacterial flagellum%3B Structural component of flagellum%2C the bacterial motility apparatus. Part of the rod structure of flagellar basal body%3B Belongs to the flagella basal body rod proteins family gene gene1223 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01224 S100141_01225 S100141_01225 S100141_01225 1113238 1113690 + Flagellar basal-body rod protein FlgC Bacterial flagellum%3B Belongs to the flagella basal body rod proteins family gene gene1224 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01225 S100141_01226 S100141_01226 S100141_01226 1113704 1114021 + Flagellar hook-basal body complex protein FliE Bacterial flagellum%3B Belongs to the FliE family gene gene1225 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01226 S100141_01227 S100141_01227 S100141_01227 1114072 1115673 + Flagellar M-ring protein Bacterial flagellum%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B The M ring may be actively involved in energy transduction. Belongs to the FliF family gene gene1226 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01227 S100141_01228 S100141_01228 S100141_01228 1115687 1116703 + Flagellar motor switch protein FliG Bacterial flagellum%3B Cell membrane%3B Chemotaxis%3B Flagellar rotation%3B Membrane%3B One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliG family gene gene1227 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01228 S100141_01229 S100141_01229 S100141_01229 1116687 1117454 + putative flagellar assembly protein FliH Bacterial flagellum biogenesis%3B Bacterial flagellum protein export%3B Protein transport%3B Transport%3B Needed for flagellar regrowth and assembly. Belongs to the FliH family gene gene1228 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01229 S100141_01230 S100141_01230 fliI fliI 1117454 1118767 + H(+)-transporting two-sector ATPase ATP synthesis%3B ATP-binding%3B Bacterial flagellum biogenesis%3B Bacterial flagellum protein export%3B Cytoplasm%3B Hydrogen ion transport%3B Hydrolase%3B Ion transport%3B Nucleotide-binding%3B Protein transport%3B Transport%3B Probable catalytic subunit of a protein translocase for flagellum-specific export%2C or a proton translocase involved in local circuits at the flagellum. Belongs to the ATPase alpha/beta chains family%3B KEGG: bli:BL01269 flagellum-specific ATP synthase gene gene1229 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01230 S100141_01231 S100141_01231 S100141_01231 1118770 1119213 + Flagellar FliJ protein Bacterial flagellum biogenesis%3B Bacterial flagellum protein export%3B Cell membrane%3B Chemotaxis%3B Membrane%3B Protein transport%3B Transport%3B Flagellar protein that affects chemotactic events%3B Belongs to the FliJ family gene gene1230 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01231 S100141_01232 S100141_01232 S100141_01232 1119227 1119838 + FlaA locus 22.9 kDa protein Bacterial flagellum biogenesis. gene gene1231 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01232 S100141_01233 S100141_01233 S100141_01233 1119840 1121219 + putative flagellar hook-length control protein Bacterial flagellum biogenesis%3B Controls the length of the flagellar hook%3B Belongs to the FliK family gene gene1232 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01233 S100141_01234 S100141_01234 S100141_01234 1121219 1121686 + FlaA locus uncharacterized protein YlxG Bacterial flagellum biogenesis%3B Belongs to the FlgD family gene gene1233 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01234 S100141_01235 S100141_01235 S100141_01235 1121714 1122505 + Flagellar hook protein FlgE Bacterial flagellum%3B Belongs to the flagella basal body rod proteins family gene gene1234 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01235 S100141_01236 S100141_01236 S100141_01236 1122760 1123191 + Flagellar protein FliL Cell membrane%3B Chemotaxis%3B Flagellar rotation%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Controls the rotational direction of flagella during chemotaxis. Belongs to the FliL family gene gene1235 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01236 S100141_01237 S100141_01237 S100141_01237 1123227 1124225 + Flagellar motor switch protein FliM Bacterial flagellum%3B Cell membrane%3B Chemotaxis%3B Flagellar rotation%3B Membrane%3B One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliM family gene gene1236 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01237 S100141_01238 S100141_01238 S100141_01238 1124215 1125348 + Flagellar motor switch phosphatase FliY Cell membrane%3B Chemotaxis%3B Flagellar rotation%3B Hydrolase%3B Membrane%3B Component of the flagellar switch. Binds CheY-P and increases its hydrolysis rate in vitro. May function constitutively to remove CheY-P around the flagellar switch to maintain an optimal level of CheY-P whereas CheC may function after addition of an attractant to cope with increased levels of CheY-P%3B Belongs to the FliN/MopA/SpaO family gene gene1237 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01238 S100141_01239 S100141_01239 S100141_01239 1125375 1125737 + Chemotaxis protein CheY Chemotaxis%3B Cytoplasm%3B Magnesium%3B Metal-binding%3B Phosphoprotein%3B Two-component regulatory system%3B Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. Phosphorylated CheY interacts with the flagella switch components FliM and FliY%2C which causes counterclockwise rotation of the flagella%2C resulting in smooth swimming%3B Contains 1 response regulatory domain gene gene1238 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01239 S100141_01240 S100141_01240 S100141_01240 1125750 1126424 + Flagellar biosynthetic protein FliZ Bacterial flagellum biogenesis%3B Cell membrane%3B Membrane%3B Signal%3B Transmembrane%3B Transmembrane helix. gene gene1239 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01240 S100141_01241 S100141_01241 S100141_01241 1126417 1127082 + Flagellar biosynthetic protein FliP Bacterial flagellum biogenesis%3B Bacterial flagellum protein export%3B Cell membrane%3B Membrane%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Plays a role in the flagellum-specific transport system%3B Belongs to the FliP/MopC/SpaP family gene gene1240 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01241 S100141_01242 S100141_01242 S100141_01242 1127098 1127367 + Flagellar biosynthetic protein FliQ Bacterial flagellum%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family gene gene1241 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01242 S100141_01243 S100141_01243 S100141_01243 1127375 1128151 + Flagellar biosynthetic protein FliR Bacterial flagellum%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family gene gene1242 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01243 S100141_01244 S100141_01244 S100141_01244 1128148 1129230 + Flagellar biosynthetic protein FlhB Bacterial flagellum biogenesis%3B Bacterial flagellum protein export%3B Cell membrane%3B Membrane%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B May be involved in the export of flagellum proteins. Belongs to the type III secretion exporter family gene gene1243 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01244 S100141_01245 S100141_01245 S100141_01245 1129264 1131300 + Flagellar biosynthesis protein FlhA Bacterial flagellum biogenesis%3B Bacterial flagellum protein export%3B Cell membrane%3B Membrane%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the export of flagellum proteins. Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family gene gene1244 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01245 S100141_01246 S100141_01246 S100141_01246 1131297 1132409 + Flagellar biosynthesis protein FlhF Bacterial flagellum biogenesis%3B Bacterial flagellum protein export%3B Cell membrane%3B GTP-binding%3B Membrane%3B Nucleotide-binding%3B Protein transport%3B Transport%3B Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum. Belongs to the GTP-binding SRP family gene gene1245 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01246 S100141_01247 S100141_01247 S100141_01247 1132406 1133299 + Flagellum site-determining protein YlxH ATP-binding%3B Bacterial flagellum biogenesis%3B Nucleotide-binding%3B Involved in the placement and assembly of flagella (By similarity). Activates the SRP-GTPase activity of FlhF%3B Belongs to the ParA family gene gene1246 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01247 S100141_01248 S100141_01248 S100141_01248 1133296 1134369 + Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon Chemotaxis%3B Cytoplasm%3B Hydrolase%3B Phosphoprotein%3B Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene1247 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01248 S100141_01249 S100141_01249 cheA cheA 1134375 1136396 + Histidine kinase ATP-binding%3B Chemotaxis%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Two-component regulatory system%3B Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylate%3B it can transfer its phosphate group to CheB%2C CheY or CheV%3B Contains 1 cheW-like domain%3B Contains 1 histidine kinase domain%3B Contains 1 HPt domain%3B KEGG: xcc:XCC2700 two-component system%2C chemotaxis family%2C sensor kinase CheA gene gene1248 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01249 S100141_01250 S100141_01250 S100141_01250 1136420 1136896 + Chemotaxis protein CheW Chemotaxis%3B Cytoplasm%3B Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheV and CheW are involved in the coupling of the methyl-accepting chemoreceptors to the central two-component kinase Che%3B they are both necessary for efficient chemotaxis%3B Contains 1 cheW-like domain gene gene1249 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01250 S100141_01251 S100141_01251 S100141_01251 1136907 1137536 + CheY-P phosphatase CheC Chemotaxis%3B Hydrolase%3B Involved in restoring normal CheY-P levels following the addition of attractant by increasing the rate of CheY-P hydrolysis. Is only 6%25 as active as FliY%2C which indicates that CheC may function after addition of an attractant to cope with increased levels of CheY-P whereas FliY may function constitutively to remove CheY-P around the flagellar switch to maintain an optimal level of CheY-P. In addition%2C it was shown to prevent methylation of the methyl-accepting chemotaxis proteins (MCPs). Inhibits CheD%3B Belongs to the CheC family gene gene1250 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01251 S100141_01252 S100141_01252 cheD cheD 1137533 1138039 + Protein-glutamine glutaminase Chemotaxis%3B Hydrolase%3B Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase (By similarity)%3B Belongs to the CheD family%3B KEGG: bli:BL01247 chemotaxis protein CheD gene gene1251 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01252 S100141_01253 S100141_01253 S100141_01253 1138062 1138826 + RNA polymerase sigma-D factor DNA-binding%3B Sigma factor%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This alternative sigma factor is required for the transcription of the flagellin and motility genes as well as for wild-type chemotaxis. Belongs to the sigma-70 factor family gene gene1252 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01253 S100141_01254 S100141_01254 S100141_01254 1138921 1139433 + Swarming motility protein SwrB Required for swarming motility and for maximal sigma-D activity gene gene1253 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01254 S100141_01255 S100141_01255 S100141_01255 1139587 1140327 + 30S ribosomal protein S2 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein S2P family gene gene1254 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01255 S100141_01256 S100141_01256 S100141_01256 1140428 1141309 + Elongation factor Ts Cytoplasm%3B Elongation factor%3B Protein biosynthesis%3B Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA. EF- Tu. GTP complex up to the GTP hydrolysis stage on the ribosome%3B Belongs to the EF-Ts family gene gene1255 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01256 S100141_01257 S100141_01257 pyrH pyrH 1141459 1142181 + UMP kinase Allosteric enzyme%3B ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Pyrimidine biosynthesis%3B Transferase%3B Catalyzes the reversible phosphorylation of UMP to UDP%3B Belongs to the UMP kinase family%3B KEGG: ssan:NX02_14365 uridylate kinase gene gene1256 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01257 S100141_01258 S100141_01258 S100141_01258 1142183 1142740 + Ribosome-recycling factor Cytoplasm%3B Protein biosynthesis%3B Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another%3B Belongs to the RRF family gene gene1257 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01258 S100141_01259 S100141_01259 uppS uppS 1142870 1143652 + Ditrans%2Cpolycis-undecaprenyl-diphosphate synthase ((2E%2C6E)-farnesyl-diphosphate specific) Magnesium%3B Metal-binding%3B Transferase%3B Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids%3B Belongs to the UPP synthase family%3B KEGG: bsu:BSU16530 undecaprenyl diphosphate synthase gene gene1258 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01259 S100141_01260 S100141_01260 cds1 cds1 1143665 1144468 + Phosphatidate cytidylyltransferase Cell membrane%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Nucleotidyltransferase%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Belongs to the CDS family%3B KEGG: bsu:BSU16540 phosphatidate cytidylyltransferase gene gene1259 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01260 S100141_01261 S100141_01261 S100141_01261 1144515 1145666 + 1-deoxy-D-xylulose-5-phosphate reductoisomerase Isoprene biosynthesis%3B Metal-binding%3B NADP%3B Oxidoreductase%3B Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)%3B Belongs to the DXR family%3B KEGG: pat:Patl_1255 1-deoxy-D-xylulose-5-phosphate reductoisomerase gene gene1260 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01261 S100141_01262 S100141_01262 rseP rseP 1145679 1146938 + putative protease eep Cell membrane%3B Hydrolase%3B Membrane%3B Metal-binding%3B Metalloprotease%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Zinc%3B Involved in production of the peptide pheromone cAD1. Belongs to the peptidase M50B family%3B Contains 1 PDZ (DHR) domain%3B KEGG: tcx:Tcr_1279 regulator of sigma E protease%3B Metalloendopeptidases gene gene1261 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01262 S100141_01263 S100141_01263 parS parS 1147048 1148766 + Proline--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine%2C to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS%3B Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily%3B KEGG: bli:BL01235 prolyl-tRNA synthetase gene gene1262 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01263 S100141_01264 S100141_01264 polC polC 1148855 1153171 + DNA-directed DNA polymerase Antibiotic resistance%3B Cytoplasm%3B DNA replication%3B DNA-directed DNA polymerase%3B Exonuclease%3B Hydrolase%3B Nuclease%3B Nucleotidyltransferase%3B Transferase%3B Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. Belongs to the DNA polymerase type-C family. PolC subfamily%3B Contains 1 exonuclease domain%3B KEGG: bsut:BSUB_01790 DNA polymerase III subunit alpha%2C Gram-positive type gene gene1263 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01264 S100141_01265 S100141_01265 S100141_01265 1153586 1153861 + Cellulase Carbohydrate metabolism%3B Cellulose degradation%3B Glycosidase%3B Hydrolase%3B Polysaccharide degradation%3B Secreted%3B Signal%3B Belongs to the glycosyl hydrolase 9 (cellulase E) family%3B Contains 1 CBM3 (carbohydrate binding type-3) domain%3B KEGG: csc:Csac_1079 endoglucanase%3B overlaps another CDS with the same product name gene gene1264 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01265 S100141_01266 S100141_01266 S100141_01266 1153812 1155551 + Cellulase Carbohydrate metabolism%3B Cell wall biogenesis/degradation%3B Cellulose degradation%3B Glycoprotein%3B Glycosidase%3B Hydrolase%3B Polysaccharide degradation%3B Secreted%3B Signal%3B Belongs to the glycosyl hydrolase 9 (cellulase E) family%3B KEGG: csc:Csac_1079 endoglucanase%3B overlaps another CDS with the same product name gene gene1265 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01266 S100141_01267 S100141_01267 S100141_01267 1155579 1157693 + Cellulose 1%2C4-beta-cellobiosidase (non-reducing end) Carbohydrate metabolism%3B Cellulose degradation%3B Glycosidase%3B Hydrolase%3B Polysaccharide degradation%3B Signal%3B Belongs to the glycosyl hydrolase 48 (cellulase L) family%3B Contains 1 CBM3 (carbohydrate binding type-3) domain%3B KEGG: cth:Cthe_0071 cellulose 1%2C4-beta-cellobiosidase gene gene1266 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01267 S100141_01268 S100141_01268 S100141_01268 1157798 1159480 + Cellulase Carbohydrate metabolism%3B Cellulose degradation%3B Glycosidase%3B Hydrolase%3B Polysaccharide degradation%3B Signal%3B Has endoglucanase activity on carboxymethyl-cellulose (CMC)%2C xylan and lichenan%2C but not Avicel. Belongs to the glycosyl hydrolase 5 (cellulase A) family%3B Contains 1 dockerin domain%3B KEGG: bli:BL01230 endoglucanase gene gene1267 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01268 S100141_01269 S100141_01269 S100141_01269 1159544 1160731 + Mannan endo-1%2C4-beta-mannosidase Carbohydrate metabolism%3B Glycoprotein%3B Glycosidase%3B Hydrolase%3B Secreted%3B Signal%3B Endo-1%2C4-mannanase%2C a crucial enzyme for depolymerization of seed galactomannans and wood galactoglucomannans%3B Belongs to the glycosyl hydrolase 5 (cellulase A) family%3B KEGG: bli:BL01229 mannan endo-1%2C4-beta-mannosidase gene gene1268 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01269 S100141_01270 S100141_01270 S100141_01270 1160925 1161398 + Ribosome maturation factor RimP Cytoplasm%3B Ribosome biogenesis%3B Required for maturation of 30S ribosomal subunits%3B Belongs to the RimP family gene gene1269 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01270 S100141_01271 S100141_01271 S100141_01271 1161430 1162548 + Transcription termination/antitermination protein NusA Cytoplasm%3B RNA-binding%3B Transcription%3B Transcription antitermination%3B Transcription regulation%3B Transcription termination%3B Participates in both transcription termination and antitermination%3B Belongs to the NusA family%3B Contains 1 KH domain%3B Contains 1 S1 motif domain gene gene1270 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01271 S100141_01272 S100141_01272 S100141_01272 1162562 1162837 + uncharacterized protein gene gene1271 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01272 S100141_01273 S100141_01273 S100141_01273 1162838 1163140 + putative ribosomal protein YlxQ Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B RNA-binding protein that recognizes the K-turn motif present in ribosomal RNA%2C but also in box C/D and box C'/D' sRNAs%3B Belongs to the ribosomal protein L7Ae family gene gene1272 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01273 S100141_01274 S100141_01274 S100141_01274 1163161 1165311 + Translation initiation factor IF-2 Cytoplasm%3B GTP-binding%3B Initiation factor%3B Nucleotide-binding%3B Protein biosynthesis%3B One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene1273 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01274 S100141_01275 S100141_01275 S100141_01275 1165308 1165586 + uncharacterized protein gene gene1274 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01275 S100141_01276 S100141_01276 S100141_01276 1165605 1165958 + Ribosome-binding factor Cytoplasm%3B rRNA processing%3B Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA%3B Belongs to the RbfA family gene gene1275 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01276 S100141_01277 S100141_01277 truB truB 1166030 1166959 + tRNA pseudouridine(55) synthase Isomerase%3B tRNA processing%3B Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs%3B Belongs to the pseudouridine synthase TruB family. Type 1 subfamily%3B KEGG: ben:BOBLI757_107 tRNA pseudouridine55 synthase gene gene1276 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01277 S100141_01278 S100141_01278 ribF ribF 1166975 1167934 + Riboflavin kinase ATP-binding%3B FAD%3B Flavoprotein%3B FMN%3B Kinase%3B Multifunctional enzyme%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase%3B Belongs to the RibF family%3B KEGG: bsu:BSU16670 riboflavin kinase / FMN adenylyltransferase gene gene1277 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01278 S100141_01279 S100141_01279 S100141_01279 1168120 1168389 + 30S ribosomal protein S15 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B One of the primary rRNA binding proteins%2C it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA%3B Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome%3B Belongs to the ribosomal protein S15P family gene gene1278 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01279 S100141_01280 S100141_01280 S100141_01280 1168591 1170708 + Polyribonucleotide nucleotidyltransferase Cytoplasm%3B Magnesium%3B Metal-binding%3B Nucleotidyltransferase%3B RNA-binding%3B Transferase%3B Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction%3B Belongs to the polyribonucleotide nucleotidyltransferase family%3B Contains 1 KH domain%3B Contains 1 S1 motif domain%3B KEGG: bmx:BMS_1508 polyribonucleotide nucleotidyltransferase gene gene1279 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01280 S100141_01281 S100141_01281 S100141_01281 1170855 1171817 + uncharacterized protein Hydrolase%3B Signal%3B Belongs to the polysaccharide deacetylase family%3B KEGG: baci:B1NLA3E_02370 peptidoglycan-N-acetylmuramic acid deacetylase%3B In linear amides gene gene1280 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01281 S100141_01282 S100141_01282 pqqL pqqL 1171854 1173083 + putative zinc protease YmxG Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Zinc%3B Belongs to the peptidase M16 family%3B KEGG: ftu:FTT_1321 zinc protease%3B Metalloendopeptidases gene gene1281 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01282 S100141_01283 S100141_01283 S100141_01283 1173169 1173429 + uncharacterized protein Sporulation%3B Belongs to the YlmC/YmxH family gene gene1282 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01283 S100141_01284 S100141_01284 S100141_01284 1173572 1174471 + Dipicolinate synthase subunit NADP%3B Oxidoreductase%3B Sporulation%3B Together with DpaB%2C catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)%2C which constitutes up to 10%25 of the dry weight of the spore%3B overlaps another CDS with the same product name gene gene1283 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01284 S100141_01285 S100141_01285 S100141_01285 1174471 1175061 + Dipicolinate synthase subunit NADP%3B Oxidoreductase%3B Sporulation%3B Together with DpaA%2C catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)%2C which constitutes up to 10%25 of the dry weight of the spore%3B overlaps another CDS with the same product name gene gene1284 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01285 S100141_01286 S100141_01286 S100141_01286 1175188 1176228 + Aspartate-semialdehyde dehydrogenase Amino-acid biosynthesis%3B Diaminopimelate biosynthesis%3B Lysine biosynthesis%3B Methionine biosynthesis%3B NADP%3B Oxidoreductase%3B Phosphoprotein%3B Threonine biosynthesis%3B Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate%3B Belongs to the aspartate-semialdehyde dehydrogenase family%3B KEGG: bsu:BSU16750 aspartate-semialdehyde dehydrogenase gene gene1285 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01286 S100141_01287 S100141_01287 lysC lysC 1176319 1177533 + Aspartate kinase Alternative initiation%3B Amino-acid biosynthesis%3B ATP-binding%3B Diaminopimelate biosynthesis%3B Kinase%3B Lysine biosynthesis%3B Nucleotide-binding%3B Transferase%3B Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate%2C which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine%2C isoleucine and methionine%3B Belongs to the aspartokinase family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU16760 aspartate kinase gene gene1286 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01287 S100141_01288 S100141_01288 dapA dapA 1177564 1178433 + 4-hydroxy-tetrahydrodipicolinate synthase Amino-acid biosynthesis%3B Cytoplasm%3B Diaminopimelate biosynthesis%3B Lyase%3B Lysine biosynthesis%3B Schiff base%3B Catalyzes the condensation of (S)-aspartate-beta- semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)%3B Belongs to the DapA family%3B KEGG: bli:BL01208 4-hydroxy-tetrahydrodipicolinate synthase gene gene1287 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01288 S100141_01289 S100141_01289 S100141_01289 1178581 1180245 + Ribonuclease J2 Cytoplasm%3B Endonuclease%3B Exonuclease%3B Hydrolase%3B Metal-binding%3B Nuclease%3B RNA-binding%3B rRNA processing%3B Zinc%3B Endonucleolytically cleaves the 5'-leader sequence of certain mRNAs. Endonuclease digestion by the RNase J1/J2 complex occurs at a different site and in some cases more efficiently than J1 or J2 alone. The exonuclease activity of the J1/J2 complex is highly processive on substrates longer than 5 nucleotides%2C on shorter substrates is distributive. Plays a role in mRNA maturation and stability. Appears to have a limited effect on 16S rRNA maturation%2C despite its similarity to RNase J1. This subunit alone has very poor 5'-3' exonuclease activity%3B Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily%3B KEGG: bli:BL01207 ribonuclease J%3B Acting on ester bonds gene gene1288 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01289 S100141_01290 S100141_01290 S100141_01290 1180350 1181096 + Endopeptidase Clp Cytoplasm%3B Hydrolase%3B Protease%3B Protein transport%3B Translocation%3B Transport%3B Required for efficient translocation of pre-proteins across the membrane%3B Belongs to the peptidase S14 family. TepA subfamily%3B KEGG: nth:Nther_1461 ATP-dependent Clp protease%2C protease subunit gene gene1289 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01290 S100141_01291 S100141_01291 S100141_01291 1181093 1181308 + uncharacterized protein gene gene1290 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01291 S100141_01292 S100141_01292 S100141_01292 1181428 1183773 + DNA translocase FtsK ATP-binding%3B Cell cycle%3B Cell division%3B Cell membrane%3B Chromosome partition%3B DNA-binding%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site%2C which is located within the replication terminus region. Required for activation of the Xer recombinase%2C allowing activation of chromosome unlinking by recombination (By similarity)%3B Belongs to the FtsK/SpoIIIE/SftA family%3B Contains 1 FtsK domain gene gene1291 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01292 S100141_01293 S100141_01293 S100141_01293 1183906 1184631 + putative HTH-type transcriptional regulator YmfC DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH gntR-type DNA-binding domain gene gene1292 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01293 S100141_01294 S100141_01294 S100141_01294 1184767 1185972 + Bacillibactin exporter Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in secretion of bacillibactin%3B Belongs to the major facilitator superfamily gene gene1293 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01294 S100141_01295 S100141_01295 S100141_01295 1186114 1187394 + putative inactive metalloprotease YmfF Metal-binding%3B Zinc%3B Belongs to the peptidase M16 family%3B KEGG: tid:Thein_0626 zinc protease%3B Metalloendopeptidases gene gene1294 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01295 S100141_01296 S100141_01296 S100141_01296 1187391 1188677 + Insulysin Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Zinc%3B Belongs to the peptidase M16 family%3B KEGG: bcz:BCZK3546 insulysin gene gene1295 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01296 S100141_01297 S100141_01297 S100141_01297 1188765 1189496 + 3-oxoacyl-[acyl-carrier-protein] reductase Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: vha:VIBHAR_02553 3-oxoacyl-(acyl-carrier protein) reductase gene gene1296 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01297 S100141_01298 S100141_01298 S100141_01298 1189567 1189824 + uncharacterized protein gene gene1297 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01298 S100141_01299 S100141_01299 S100141_01299 1190072 1190863 + uncharacterized protein Contains 1 ACT domain gene gene1298 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01299 S100141_01300 S100141_01300 S100141_01300 1190881 1191783 + putative membrane protein YmfM Cell membrane%3B Coiled coil%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1299 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01300 S100141_01301 S100141_01301 pgsA pgsA 1191850 1192431 + CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Cell membrane%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B This protein catalyzes the committed step to the synthesis of the acidic phospholipids%3B Belongs to the CDP-alcohol phosphatidyltransferase class-I family%3B KEGG: bsu:BSU16920 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase gene gene1300 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01301 S100141_01302 S100141_01302 pncC pncC 1192451 1193701 + Nicotinamide-nucleotide amidase Belongs to the CinA family%3B KEGG: bli:BL05163 nicotinamide-nucleotide amidase gene gene1301 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01302 S100141_01303 S100141_01303 S100141_01303 1193869 1194915 + Protein RecA ATP-binding%3B Cytoplasm%3B DNA damage%3B DNA recombination%3B DNA repair%3B DNA-binding%3B Nucleotide-binding%3B SOS response%3B It interacts with LexA causing its activation and leading to its autocatalytic cleavage%3B Belongs to the RecA family gene gene1302 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01303 S100141_01304 S100141_01304 S100141_01304 1195256 1196815 + Ribonuclease Cell membrane%3B Endonuclease%3B Hydrolase%3B Membrane%3B Nuclease%3B RNA-binding%3B Transmembrane%3B Transmembrane helix%3B Endoribonuclease that initiates mRNA decay%3B Belongs to the RNase Y family%3B Contains 1 HD domain%3B Contains 1 KH domain%3B KEGG: bli:BL03655 ribonucrease Y%3B Acting on ester bonds gene gene1303 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01304 S100141_01305 S100141_01305 S100141_01305 1196902 1197699 + uncharacterized protein gene gene1304 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01305 S100141_01306 S100141_01306 S100141_01306 1197901 1198161 + Stage V sporulation protein Cell cycle%3B Cell division%3B Septation%3B Sporulation. gene gene1305 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01306 S100141_01307 S100141_01307 dpeP dpeP 1198266 1199186 + Membrane dipeptidase Belongs to the peptidase M19 family%3B KEGG: blh:BaLi_c19560 membrane dipeptidase gene gene1306 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01307 S100141_01308 S100141_01308 S100141_01308 1199314 1200354 + L-threonine 3-dehydrogenase Cytoplasm%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Zinc%3B Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: bli:BL03658 threonine 3-dehydrogenase gene gene1307 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01308 S100141_01309 S100141_01309 gcaT gcaT 1200370 1201545 + Glycine C-acetyltransferase Biotin biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Catalyzes the decarboxylative condensation of pimeloyl- [acyl-carrier protein] and L-alanine to produce 8-amino-7- oxononanoate (AON)%2C [acyl-carrier protein]%2C and carbon dioxide%3B Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily%3B KEGG: bli:BL03659 glycine C-acetyltransferase gene gene1308 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01309 S100141_01310 S100141_01310 miaB miaB 1201689 1203218 + tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase 4Fe-4S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B S-adenosyl-L-methionine%3B Transferase%3B tRNA processing%3B Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A)%2C leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine%3B Belongs to the methylthiotransferase family. MiaB subfamily%3B Contains 1 MTTase N-terminal domain%3B Contains 1 TRAM domain%3B KEGG: bsu:BSU17010 tRNA-2-methylthio-N6-dimethylallyladenosine synthase gene gene1309 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01310 S100141_01311 S100141_01311 S100141_01311 1203220 1203651 + Polar-amino-acid-transporting ATPase May work together with YlbF to regulate community development%3B KEGG: cml:BN424_2091 polar amino acid transport system ATP-binding protein gene gene1310 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01311 S100141_01312 S100141_01312 S100141_01312 1203894 1204442 + Spore coat protein Sporulation%3B Morphogenic protein required for the assembly of the outer coat of the endospore. Is also a regulatory protein for the expression of cotA%2C cotB%2C cotC%2C cotH and other genes encoding spore outer coat proteins%3B Belongs to the CotE family gene gene1311 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01312 S100141_01313 S100141_01313 S100141_01313 1204553 1207162 + DNA mismatch repair protein MutS ATP-binding%3B DNA damage%3B DNA repair%3B DNA-binding%3B Nucleotide-binding%3B This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity%3B Belongs to the DNA mismatch repair MutS family gene gene1312 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01313 S100141_01314 S100141_01314 S100141_01314 1207180 1209090 + DNA mismatch repair protein MutL DNA damage%3B DNA repair%3B This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker'%2C a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex%3B Belongs to the DNA mismatch repair MutL/HexB family gene gene1313 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01314 S100141_01315 S100141_01315 pcaC pcaC 1209425 1209706 + 4-carboxymuconolactone decarboxylase Contains 1 ABM domain%3B KEGG: mme:Marme_0104 4-carboxymuconolactone decarboxylase gene gene1314 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01315 S100141_01316 S100141_01316 S100141_01316 1209888 1210415 + Ribonuclease YxiD Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene1315 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01316 S100141_01317 S100141_01317 S100141_01317 1210675 1211154 + hypothetical protein gene gene1316 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01317 S100141_01318 S100141_01318 S100141_01318 1211234 1211506 + hypothetical protein gene gene1317 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01318 S100141_01319 S100141_01319 S100141_01319 1211658 1212644 - Putative metal chaperone YciC Chaperone%3B GTP-binding%3B Nucleotide-binding%3B Zinc%3B May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc%3B Belongs to the SIMIBI class G3E GTPase family. CobW subfamily%3B Contains 1 cobW C-terminal domain gene gene1318 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01319 S100141_01320 S100141_01320 nuoF nuoF 1212661 1213047 - NADH:ubiquinone reductase (H(+)-translocating) 2Fe-2S%3B Electron transport%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Transport%3B Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions%3B Belongs to the 2Fe2S Shethna-type ferredoxin family%3B KEGG: dmt:DESME_04270 NADH-quinone oxidoreductase subunit F gene gene1319 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01320 S100141_01321 S100141_01321 S100141_01321 1213426 1213920 - Phosphinothricin acetyltransferase Acyltransferase%3B Transferase%3B Plays a role in the resistance against the toxic effects of L-methionine sulfoximine (MSX)%2C a rare amino acid%2C which inhibits glutamine synthetase (GlnA). Catalyzes the acetylation of L-methionine sulfoximine (MSX). It can also use L-methionine sulfone (MSO)%3B Contains 1 N-acetyltransferase domain%3B KEGG: bli:BL00151 phosphinothricin acetyltransferase gene gene1320 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01321 S100141_01322 S100141_01322 S100141_01322 1214131 1214778 - hypothetical protein gene gene1321 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01322 S100141_01323 S100141_01323 S100141_01323 1215052 1215162 - hypothetical protein gene gene1322 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01323 S100141_01324 S100141_01324 aofH aofH 1215393 1216835 + Monoamine oxidase FAD%3B Flavoprotein%3B Oxidoreductase%3B Belongs to the flavin monoamine oxidase family. FIG1 subfamily%3B KEGG: blh:BaLi_c19750 monoamine oxidase gene gene1323 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01324 S100141_01325 S100141_01325 S100141_01325 1217284 1217961 + UPF0700 transmembrane protein YoaK Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0700 family gene gene1324 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01325 S100141_01326 S100141_01326 S100141_01326 1218097 1219566 + K(+)/H(+) antiporter NhaP2 Antiport%3B Cell inner membrane%3B Cell membrane%3B Ion transport%3B Membrane%3B Potassium%3B Potassium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels%3B Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2. A. 36) family. NhaP2 subfamily%3B Contains 1 RCK C-terminal domain gene gene1325 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01326 S100141_01327 S100141_01327 S100141_01327 1219874 1220437 + Tetracycline resistance protein Antibiotic resistance%3B Antiport%3B Cell membrane%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter. Belongs to the major facilitator superfamily. TCR/Tet family%3B overlaps another CDS with the same product name gene gene1326 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01327 S100141_01328 S100141_01328 S100141_01328 1220403 1221248 + Tetracycline resistance protein Antibiotic resistance%3B Antiport%3B Cell membrane%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Plasmid%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter. Belongs to the major facilitator superfamily. TCR/Tet family%3B overlaps another CDS with the same product name gene gene1327 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01328 S100141_01329 S100141_01329 menH menH 1221362 1222228 + 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate synthase Hydrolase%3B Belongs to the AB hydrolase superfamily%3B KEGG: vir:X953_13270 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate synthase gene gene1328 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01329 S100141_01330 S100141_01330 S100141_01330 1222796 1223107 + UPF0145 protein Belongs to the UPF0145 family gene gene1329 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01330 S100141_01331 S100141_01331 S100141_01331 1223156 1223806 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1330 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01331 S100141_01332 S100141_01332 S100141_01332 1223840 1224856 - Serine-type D-Ala-D-Ala carboxypeptidase Antibiotic resistance%3B Cell membrane%3B Cell wall biogenesis/degradation%3B Membrane%3B Signal%3B Affects the methicillin resistance level and autolysis in the presence of Triton X-100 as well as the cell wall structure but its precise function is unknown%3B KEGG: msm:MSMEG_4455 D-alanyl-D-alanine carboxypeptidase gene gene1331 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01332 S100141_01333 S100141_01333 S100141_01333 1225312 1226502 + Demethyllactenocin mycarosyltransferase Antibiotic biosynthesis%3B Transferase%3B Involved in the biosynthesis of mycarose which is a 6- deoxyhexose sugar required during production of the macrolide antibiotic tylosin. Catalyzes the transfer of L-mycarosyl from dTDP-beta-L-mycarose to demethyllactenocin to yield demethylmacrocin%3B Belongs to the UDP-glycosyltransferase family%3B KEGG: sma:SAV_945 dTDP-L-oleandrosyltransferase%3B Hexosyltransferases gene gene1332 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01333 S100141_01334 S100141_01334 S100141_01334 1226628 1228205 + Aspartate-proton symporter Amino-acid transport%3B Cell membrane%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Uptake of L-aspartate with the concomitant import of a proton. Can also transport aspartate hydroxamate and L-glutamate with lower affinity and efficiency. Belongs to the amino acid-polyamine-organocation (APC) superfamily. AGT (TC 2. A. 3. 11) family gene gene1333 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01334 S100141_01335 S100141_01335 S100141_01335 1228253 1228552 - Spore coat protein F-like protein YraD Sporulation%3B Belongs to the CotF family gene gene1334 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01335 S100141_01336 S100141_01336 S100141_01336 1228549 1228749 - uncharacterized protein gene gene1335 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01336 S100141_01337 S100141_01337 S100141_01337 1228861 1230129 - N-acetylmuramoyl-L-alanine amidase Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Polysaccharide degradation%3B Repeat%3B Sporulation%3B Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily%3B Contains 2 LysM repeats%3B KEGG: mta:Moth_0054 N-acetylmuramoyl-L-alanine amidase gene gene1336 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01337 S100141_01338 S100141_01338 S100141_01338 1230303 1230887 + putative HTH-type transcriptional regulator YezE DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH tetR-type DNA-binding domain gene gene1337 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01338 S100141_01339 S100141_01339 S100141_01339 1230975 1231394 + uncharacterized protein Belongs to the limonene-1%2C2-epoxide hydrolase family gene gene1338 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01339 S100141_01340 S100141_01340 qorB qorB 1231415 1232260 + NAD(P)H dehydrogenase (quinone) Oxidoreductase%3B Belongs to the NmrA-type oxidoreductase family%3B KEGG: sxi:SXIM_50260 NAD(P)H dehydrogenase (quinone) gene gene1339 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01340 S100141_01341 S100141_01341 S100141_01341 1232315 1232620 - hypothetical protein gene gene1340 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01341 S100141_01342 S100141_01342 S100141_01342 1232778 1233233 + uncharacterized protein Belongs to the OsmC/Ohr family gene gene1341 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01342 S100141_01343 S100141_01343 S100141_01343 1233230 1233589 - Multidrug resistance protein EbrB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of a multidrug efflux pump. Confers resistance to cationic lipophilic dyes such as ethidium bromide%2C acriflavine%2C pyronine Y and safranin O. The efflux is probably coupled to an influx of protons%3B Belongs to the small multidrug resistance (SMR) protein family. EbrA/EbrB (TC 2. A. 7. 1. 6) subfamily gene gene1342 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01343 S100141_01344 S100141_01344 S100141_01344 1233603 1233920 - Multidrug resistance protein EbrA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of a multidrug efflux pump. Confers resistance to cationic lipophilic dyes such as ethidium bromide%2C acriflavine%2C pyronine Y and safranin O. The efflux is probably coupled to an influx of protons (By similarity)%3B Belongs to the small multidrug resistance (SMR) protein family. EbrA/EbrB (TC 2. A. 7. 1. 6) subfamily gene gene1343 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01344 S100141_01345 S100141_01345 S100141_01345 1234328 1234549 - hypothetical protein gene gene1344 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01345 S100141_01346 S100141_01346 S100141_01346 1234675 1235076 + uncharacterized protein gene gene1345 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01346 S100141_01347 S100141_01347 miaA miaA 1235178 1236122 + tRNA dimethylallyltransferase ATP-binding%3B Magnesium%3B Nucleotide-binding%3B Transferase%3B tRNA processing%3B Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine%2C leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)%3B Belongs to the IPP transferase family%3B KEGG: bli:BL05174 tRNA dimethylallyltransferase gene gene1346 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01347 S100141_01348 S100141_01348 S100141_01348 1236164 1236385 + RNA-binding protein Hfq RNA-binding%3B Stress response%3B RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress%2C environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs%3B Belongs to the Hfq family gene gene1347 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01348 S100141_01349 S100141_01349 S100141_01349 1236676 1236888 + uncharacterized protein gene gene1348 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01349 S100141_01350 S100141_01350 S100141_01350 1237135 1237533 + Protein NrdI Probably involved in ribonucleotide reductase function%3B Belongs to the NrdI family gene gene1349 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01350 S100141_01351 S100141_01351 S100141_01351 1237490 1239592 + Ribonucleoside-diphosphate reductase Allosteric enzyme%3B ATP-binding%3B Disulfide bond%3B DNA replication%3B Nucleotide-binding%3B Oxidoreductase%3B Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase large chain family%3B KEGG: bsu:BSU17380 ribonucleoside-diphosphate reductase alpha chain%3B overlaps another CDS with the same product name gene gene1350 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01351 S100141_01352 S100141_01352 S100141_01352 1239580 1240590 + Ribonucleoside-diphosphate reductase DNA replication%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase small chain family%3B KEGG: bsu:BSU17390 ribonucleoside-diphosphate reductase beta chain%3B overlaps another CDS with the same product name gene gene1351 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01352 S100141_01353 S100141_01353 S100141_01353 1240704 1241321 + uncharacterized protein gene gene1352 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01353 S100141_01354 S100141_01354 S100141_01354 1241206 1241907 - hypothetical protein gene gene1353 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01354 S100141_01355 S100141_01355 S100141_01355 1241892 1242119 - hypothetical protein gene gene1354 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01355 S100141_01356 S100141_01356 S100141_01356 1242333 1242764 + Iron-sulfur cluster assembly scaffold protein IscU Metal-binding%3B Zinc%3B A scaffold on which IscS assembles Fe-S clusters. Subsequently gives the nascent cluster to other proteins. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters (By similarity)%3B Belongs to the NifU family gene gene1355 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01356 S100141_01357 S100141_01357 S100141_01357 1242891 1243322 + Peroxide-responsive repressor PerR Cytoplasm%3B DNA-binding%3B Manganese%3B Metal-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Zinc%3B Manganese-dependent repressor that controls a regulon of oxidative stress resistance and iron-storage proteins. May act as a hydrogen peroxide and organic hydroperoxide sensor (By similarity)%3B Belongs to the Fur family gene gene1356 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01357 S100141_01358 S100141_01358 S100141_01358 1243328 1244032 + HTH-type transcriptional regulator McbR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Important for biofilm formation. Represses expression of McbA by binding to its promoter region%2C which prevents colanic acid overproduction and mucoidy%3B Contains 1 HTH gntR-type DNA-binding domain gene gene1357 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01358 S100141_01359 S100141_01359 S100141_01359 1244040 1245008 + putative 42.1 kDa protein in intracellular alkaline protease 3'region gene gene1358 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01359 S100141_01360 S100141_01360 S100141_01360 1245063 1245824 - N-acetylmuramoyl-L-alanine amidase Cell wall%3B Cell wall biogenesis/degradation%3B Competence%3B Hydrolase%3B Metal-binding%3B Repeat%3B Secreted%3B Sporulation%3B Zinc%3B Autolysins are involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella - in particular of its basal body - and sporulation. CwlC is able to hydrolyze type A cell walls such as B. subtilis. Its main function is to lyze the mother cell wall peptidoglycan%2C playing a role during sporulation%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B Contains 1 SPOR domain%3B KEGG: bsu:BSU17410 N-acetylmuramoyl-L-alanine amidase gene gene1359 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01360 S100141_01361 S100141_01361 S100141_01361 1246357 1246839 - hypothetical protein gene gene1360 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01361 S100141_01362 S100141_01362 S100141_01362 1246862 1247314 - hypothetical protein gene gene1361 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01362 S100141_01363 S100141_01363 S100141_01363 1247414 1247659 - hypothetical protein gene gene1362 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01363 S100141_01364 S100141_01364 S100141_01364 1247842 1248045 + Repressor rok Coiled coil%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation. gene gene1363 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01364 S100141_01365 S100141_01365 S100141_01365 1248259 1248882 + HTH-type transcriptional repressor KstR2 DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Controls the expression of a small regulon that may play a role in the utilization of cholesterol%3B Contains 1 HTH tetR-type DNA-binding domain gene gene1364 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01365 S100141_01366 S100141_01366 S100141_01366 1248885 1249271 + hypothetical protein gene gene1365 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01366 S100141_01367 S100141_01367 S100141_01367 1249304 1250653 + Cytosine permease Cell inner membrane%3B Cell membrane%3B Cytosine metabolism%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Required for cytosine transport into the cell. Belongs to the purine-cytosine permease (2. A. 39) family gene gene1366 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01367 S100141_01368 S100141_01368 hyuA hyuA 1250678 1252783 + N-methylhydantoinase (ATP-hydrolyzing) ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Catalyzes the carboxylation of acetophenone to form 3- oxo-3-phenylpropanoate (benzoylacetate) in the anaerobic catabolism of ethylbenzene. Also carboxylates propiophenone at the same rate and 4-acetyl-pyridine at lower rates%3B Belongs to the oxoprolinase family%3B KEGG: bld:BLi01982 N-methylhydantoinase A%3B overlaps another CDS with the same product name gene gene1367 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01368 S100141_01369 S100141_01369 hyuB hyuB 1252780 1254258 + N-methylhydantoinase (ATP-hydrolyzing) ATP-binding%3B Cytoplasm%3B Hydrolase%3B Nucleotide-binding%3B Catalyzes the cleavage of 5-oxo-L-proline to form L- glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. Acts in the glutathione degradation pathway%3B Belongs to the oxoprolinase family%3B KEGG: baci:B1NLA3E_09215 N-methylhydantoinase B%3B overlaps another CDS with the same product name gene gene1368 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01369 S100141_01370 S100141_01370 S100141_01370 1254255 1255994 + N-methylhydantoinase (ATP-hydrolyzing) ATP-binding%3B Hydrolase%3B Nucleotide-binding%3B Phosphoprotein%3B Catalyzes the cleavage of 5-oxo-L-proline to form L- glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. Belongs to the oxoprolinase family%3B KEGG: bli:BL00460 N-methylhydantoinase B%3B overlaps another CDS with the same product name gene gene1369 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01370 S100141_01371 S100141_01371 S100141_01371 1256167 1256601 + hypothetical protein gene gene1370 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01371 S100141_01372 S100141_01372 S100141_01372 1256894 1257070 + hypothetical protein gene gene1371 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01372 S100141_01373 S100141_01373 S100141_01373 1257278 1257838 + uncharacterized protein gene gene1372 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01373 S100141_01374 S100141_01374 S100141_01374 1257997 1259949 + Ribonuclease YxiD Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene1373 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01374 S100141_01375 S100141_01375 S100141_01375 1259983 1260438 + hypothetical protein gene gene1374 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01375 S100141_01376 S100141_01376 S100141_01376 1260851 1261042 + hypothetical protein gene gene1375 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01376 S100141_01377 S100141_01377 S100141_01377 1261612 1262310 + hypothetical protein gene gene1376 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01377 S100141_01378 S100141_01378 S100141_01378 1262725 1263690 + Stage V sporulation protein ATP-binding%3B Nucleotide-binding%3B Sporulation%3B Belongs to the cbxX/cfxQ family gene gene1377 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01378 S100141_01379 S100141_01379 S100141_01379 1263794 1265056 + GTPase HflX Cytoplasm%3B GTP-binding%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis%3B Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family%3B Contains 1 Hflx-type G (guanine nucleotide-binding) domain gene gene1378 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01379 S100141_01380 S100141_01380 S100141_01380 1265075 1266340 + Cystathionine gamma-lyase KEGG: ava:Ava_4213 cystathionine gamma-lyase gene gene1379 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01380 S100141_01381 S100141_01381 S100141_01381 1266443 1266850 + HTH-type transcriptional regulator GlnR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Represses many genes including the glnRA operon and tnrA during growth with nitrogen excess%3B Contains 1 HTH merR-type DNA-binding domain gene gene1380 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01381 S100141_01382 S100141_01382 glnA glnA 1266907 1268241 + Glutamate--ammonia ligase ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Phosphoprotein%3B Belongs to the glutamine synthetase family%3B KEGG: bsu:BSU17460 glutamine synthetase gene gene1381 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01382 S100141_01383 S100141_01383 S100141_01383 1268572 1268775 + hypothetical protein gene gene1382 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01383 S100141_01384 S100141_01384 S100141_01384 1268857 1269024 - hypothetical protein gene gene1383 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01384 S100141_01385 S100141_01385 S100141_01385 1269876 1270343 + hypothetical protein gene gene1384 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01385 S100141_01386 S100141_01386 S100141_01386 1270345 1271781 + hypothetical protein gene gene1385 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01386 S100141_01387 S100141_01387 S100141_01387 1271908 1272225 - hypothetical protein gene gene1386 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01387 S100141_01388 S100141_01388 S100141_01388 1272577 1273005 + putative HIT-like protein Contains 1 HIT domain gene gene1387 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01388 S100141_01389 S100141_01389 S100141_01389 1273165 1273581 + hypothetical protein gene gene1388 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01389 S100141_01390 S100141_01390 S100141_01390 1273649 1273951 + hypothetical protein gene gene1389 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01390 S100141_01391 S100141_01391 S100141_01391 1274186 1275160 + uncharacterized protein gene gene1390 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01391 S100141_01392 S100141_01392 S100141_01392 1275227 1275469 + hypothetical protein gene gene1391 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01392 S100141_01393 S100141_01393 S100141_01393 1275522 1276001 + hypothetical protein gene gene1392 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01393 S100141_01394 S100141_01394 tehB tehB 1276143 1276739 + Tellurite methyltransferase KEGG: pmu:PM0656 tellurite methyltransferase gene gene1393 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01394 S100141_01395 S100141_01395 S100141_01395 1276845 1277324 + uncharacterized protein Signal. gene gene1394 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01395 S100141_01396 S100141_01396 S100141_01396 1277358 1277933 + hypothetical protein gene gene1395 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01396 S100141_01397 S100141_01397 S100141_01397 1278094 1278570 + Repressor rok Coiled coil%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation. gene gene1396 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01397 S100141_01398 S100141_01398 S100141_01398 1278629 1278862 + hypothetical protein gene gene1397 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01398 S100141_01399 S100141_01399 S100141_01399 1279211 1279831 - hypothetical protein gene gene1398 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01399 S100141_01400 S100141_01400 S100141_01400 1280542 1281126 + putative HTH-type transcriptional regulator YvdT DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH tetR-type DNA-binding domain gene gene1399 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01400 S100141_01401 S100141_01401 S100141_01401 1281207 1281542 + putative membrane protein YvdS Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the small multidrug resistance (SMR) protein family gene gene1400 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01401 S100141_01402 S100141_01402 S100141_01402 1281539 1281859 + Spermidine export protein MdtJ Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Catalyzes the excretion of spermidine%3B Belongs to the small multidrug resistance (SMR) protein family. MdtJ subfamily gene gene1401 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01402 S100141_01403 S100141_01403 speG speG 1281888 1282142 + Diamine N-acetyltransferase Acyltransferase%3B Cytoplasm%3B Magnesium%3B Metal-binding%3B Transferase%3B Involved in the protection against polyamine toxicity by regulating their concentration. Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to the primary amino groups of spermidine to yield N(1)- and N(8)-acetylspermidine%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: van:VAA_01303 diamine N-acetyltransferase%3B overlaps another CDS with the same product name gene gene1402 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01403 S100141_01404 S100141_01404 S100141_01404 1282111 1282419 + Diamine N-acetyltransferase Acyltransferase%3B Cytoplasm%3B Magnesium%3B Metal-binding%3B Plasmid%3B Transferase%3B Involved in the protection against polyamine toxicity by regulating their concentration. Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to the primary amino groups of spermidine to yield N(1)- and N(8)-acetylspermidine%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: mrs:Murru_0006 diamine N-acetyltransferase%3B overlaps another CDS with the same product name gene gene1403 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01404 S100141_01405 S100141_01405 S100141_01405 1282457 1282813 - hypothetical protein gene gene1404 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01405 S100141_01406 S100141_01406 S100141_01406 1282996 1283430 + uncharacterized protein Signal. gene gene1405 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01406 S100141_01407 S100141_01407 S100141_01407 1283764 1283973 + Thiol-disulfide oxidoreductase ResA Cell membrane%3B Cytochrome c-type biogenesis%3B Disulfide bond%3B Membrane%3B Oxidoreductase%3B Redox-active center%3B Signal-anchor%3B Transmembrane%3B Transmembrane helix%3B Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA%2C leading to breakage of disulfide bonds in apocytochrome%3B following this reduction heme can be covalently attached%3B Belongs to the thioredoxin family. ResA subfamily%3B Contains 1 thioredoxin domain gene gene1406 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01407 S100141_01408 S100141_01408 S100141_01408 1284122 1284985 + uncharacterized protein Belongs to the manganese catalase family gene gene1407 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01408 S100141_01409 S100141_01409 S100141_01409 1285070 1285870 + hypothetical protein gene gene1408 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01409 S100141_01410 S100141_01410 S100141_01410 1286002 1286520 + Ribosomal-protein-alanine N-acetyltransferase Acyltransferase%3B Transferase%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bce:BC2051 ribosomal-protein-alanine N-acetyltransferase gene gene1409 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01410 S100141_01411 S100141_01411 S100141_01411 1286513 1286815 + hypothetical protein gene gene1410 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01411 S100141_01412 S100141_01412 S100141_01412 1287134 1287730 + putative HTH-type transcriptional regulator YuxN DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH tetR-type DNA-binding domain gene gene1411 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01412 S100141_01413 S100141_01413 S100141_01413 1287943 1288398 + HTH-type transcriptional regulator MhqR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Negatively regulates mhqA%2C mhqED%2C mhqNOP%2C and azoR2 which may contribute to the degradation of aromatic compounds%3B Contains 1 HTH marR-type DNA-binding domain gene gene1412 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01413 S100141_01414 S100141_01414 S100141_01414 1288471 1288860 + Putative NAD(P)H nitroreductase YdgI Flavoprotein%3B FMN%3B NAD%3B NADP%3B Oxidoreductase%3B Belongs to the nitroreductase family%3B KEGG: bsr:I33_0620 putative NAD(P)H nitroreductase%3B Oxidoreductases gene gene1413 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01414 S100141_01415 S100141_01415 S100141_01415 1288958 1289896 + Putative ring-cleaving dioxygenase MhqO Aromatic hydrocarbons catabolism%3B Cytoplasm%3B Detoxification%3B Dioxygenase%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Putative ring-cleavage dioxygenase that may contribute to the degradation of aromatic compounds%3B Belongs to the extradiol ring-cleavage dioxygenase family gene gene1414 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01415 S100141_01416 S100141_01416 S100141_01416 1289918 1290526 + uncharacterized protein Flavoprotein%3B FMN%3B Belongs to the flavoredoxin family gene gene1415 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01416 S100141_01417 S100141_01417 S100141_01417 1290726 1291337 + NAD(P)H dehydrogenase (quinone) Flavoprotein%3B FMN%3B NAD%3B NADP%3B Nucleotide-binding%3B Oxidoreductase%3B It seems to function in response to environmental stress when various electron transfer chains are affected or when the environment is highly oxidizing. It reduces quinones to the hydroquinone state to prevent interaction of the semiquinone with O2 and production of superoxide (By similarity)%3B Belongs to the WrbA family%3B Contains 1 flavodoxin-like domain%3B KEGG: bli:BL02638 NAD(P)H dehydrogenase (quinone) gene gene1416 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01417 S100141_01418 S100141_01418 S100141_01418 1291791 1292624 + hypothetical protein gene gene1417 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01418 S100141_01419 S100141_01419 S100141_01419 1292718 1293476 + hypothetical protein gene gene1418 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01419 S100141_01420 S100141_01420 S100141_01420 1293536 1294375 + Thymidylate synthase Cytoplasm%3B Methyltransferase%3B Nucleotide biosynthesis%3B Transferase%3B Provides the sole de novo source of dTMP for DNA biosynthesis%3B Belongs to the thymidylate synthase family. Bacterial- type ThyA subfamily%3B KEGG: bli:BL02642 thymidylate synthase gene gene1419 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01420 S100141_01421 S100141_01421 S100141_01421 1294734 1295162 + Sporulation-specific extracellular nuclease Hydrolase%3B Manganese%3B Nuclease%3B Secreted%3B Signal%3B Sporulation%3B Degrades both double-stranded linear and covalently closed circular DNA. Likely to play a scavenging role in order to supply nutrients under starvation conditions. To B. subtilis NucA/ComI gene gene1420 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01421 S100141_01422 S100141_01422 S100141_01422 1295073 1295246 - hypothetical protein gene gene1421 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01422 S100141_01423 S100141_01423 S100141_01423 1295358 1295981 - Repressor LexA Autocatalytic cleavage%3B DNA damage%3B DNA repair%3B DNA replication%3B DNA-binding%3B Hydrolase%3B Repressor%3B SOS response%3B Transcription%3B Transcription regulation%3B Represses a number of genes involved in the response to DNA damage (SOS response)%2C including recA and lexA. In the presence of single-stranded DNA%2C RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA%2C leading to derepression of the SOS regulon and eventually DNA repair%3B Belongs to the peptidase S24 family%3B KEGG: pae:PA3007 repressor LexA gene gene1422 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01423 S100141_01424 S100141_01424 S100141_01424 1296128 1296445 + Cell division suppressor protein YneA Cell cycle%3B Cell division%3B Cytoplasm%3B DNA damage%3B DNA repair%3B Septation%3B SOS response%3B Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly%2C after the assembly of the Z ring%2C by probably suppressing recruitment of FtsL and/or DivIC to the division machinery%3B Belongs to the YneA family gene gene1423 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01424 S100141_01425 S100141_01425 S100141_01425 1296464 1297111 + Resolvase like protein YneB Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene1424 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01425 S100141_01426 S100141_01426 S100141_01426 1297177 1297410 + 5-formyltetrahydrofolate cyclo-ligase Cytoplasm%3B Belongs to the UPF0291 family%3B KEGG: rum:CK1_06990 5-formyltetrahydrofolate cyclo-ligase gene gene1425 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01426 S100141_01427 S100141_01427 tktA tktA 1297577 1299580 + Transketolase Calcium%3B Magnesium%3B Metal-binding%3B Thiamine pyrophosphate%3B Transferase%3B Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor%2C via a covalent intermediate with the cofactor thiamine pyrophosphate%3B Belongs to the transketolase family%3B KEGG: bsu:BSU17890 transketolase gene gene1426 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01427 S100141_01428 S100141_01428 S100141_01428 1299735 1300172 + Sporulation inhibitor of replication protein SirA DNA replication inhibitor%3B Sporulation%3B Inhibits DNA replication in growing cells%2C thus reducing chromosome copy number and playing a significant role during the onset of sporulation gene gene1427 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01428 S100141_01429 S100141_01429 S100141_01429 1300257 1300475 + UPF0154 protein Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0154 family gene gene1428 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01429 S100141_01430 S100141_01430 S100141_01430 1300556 1300717 - Aspartyl-phosphate phosphatase YnzD Hydrolase%3B Sporulation%3B Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation%3B Belongs to the spo0E family gene gene1429 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01430 S100141_01431 S100141_01431 S100141_01431 1300960 1301667 + Cytochrome c-type bioproteinis protein CcdA Cell membrane%3B Cytochrome c-type biogenesis%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane%2C promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat%3B Cytochrome c oxidase activity is partially restored by mutations in bdbC or bdbD that are defective in the synthesis of disulfide bond containing proteins. The same mutations abrogate the need for CcdA in sporulation%3B Belongs to the DsbD family gene gene1430 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01431 S100141_01432 S100141_01432 S100141_01432 1301749 1302120 + Protein CcdB Phosphoprotein%3B Two-component regulatory system%3B Contains 1 response regulatory domain gene gene1431 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01432 S100141_01433 S100141_01433 S100141_01433 1302203 1302688 + Protein CcdC Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1432 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01433 S100141_01434 S100141_01434 S100141_01434 1302724 1303152 - uncharacterized protein gene gene1433 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01434 S100141_01435 S100141_01435 S100141_01435 1303357 1303764 - Spore coat protein Sporulation. gene gene1434 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01435 S100141_01436 S100141_01436 acnA acnA 1304468 1307194 + Aconitate hydratase Amino-acid biosynthesis%3B Iron%3B Iron-sulfur%3B Lyase%3B Lysine biosynthesis%3B Metal-binding%3B RNA-binding%3B Tricarboxylic acid cycle%3B Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate. Also able to catalyze the hydration of cis-homoaconitate to yield (R)-homocitrate%2C but with a lower efficiency (PubMed:23106124). Could catalyze the hydration of 2- methyl-cis-aconitate to yield (2R%2C3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein (By similarity)%3B Belongs to the aconitase/IPM isomerase family%3B KEGG: bli:BL02940 aconitate hydratase gene gene1435 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01436 S100141_01437 S100141_01437 S100141_01437 1307266 1307772 + Thiol-disulfide oxidoreductase ResA Cell membrane%3B Cytochrome c-type biogenesis%3B Disulfide bond%3B Membrane%3B Oxidoreductase%3B Redox-active center%3B Signal-anchor%3B Transmembrane%3B Transmembrane helix%3B Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA%2C leading to breakage of disulfide bonds in apocytochrome%3B following this reduction heme can be covalently attached. Does not play a role in sporulation%3B Belongs to the thioredoxin family. ResA subfamily%3B Contains 1 thioredoxin domain gene gene1436 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01437 S100141_01438 S100141_01438 S100141_01438 1307844 1307969 + uncharacterized protein gene gene1437 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01438 S100141_01439 S100141_01439 S100141_01439 1308038 1308181 + Small%2C acid-soluble spore protein Sporulation%3B Belongs to the SspN family gene gene1438 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01439 S100141_01440 S100141_01440 S100141_01440 1308207 1308443 + Small%2C acid-soluble spore protein Tlp Sporulation%3B Belongs to the Tlp family gene gene1439 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01440 S100141_01441 S100141_01441 ybgC ybgC 1308550 1308966 + Putative acyl-CoA thioesterase YneP Hydrolase%3B Has acyl-CoA thioesterase activity%3B Belongs to the 4-hydroxybenzoyl-CoA thioesterase family%3B KEGG: bsr:I33_2017 acyl-CoA thioester hydrolase%3B Thiolester hydrolases gene gene1440 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01441 S100141_01442 S100141_01442 nadE nadE 1308966 1309268 + NAD(+) synthase KEGG: ble:BleG1_2142 NAD+ synthase gene gene1441 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01442 S100141_01443 S100141_01443 S100141_01443 1309500 1309862 - hypothetical protein gene gene1442 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01443 S100141_01444 S100141_01444 S100141_01444 1310207 1311238 - hypothetical protein gene gene1443 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01444 S100141_01445 S100141_01445 S100141_01445 1311562 1311849 - uncharacterized protein Belongs to the HesB/IscA family gene gene1444 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01445 S100141_01446 S100141_01446 plsY plsY 1311952 1312545 - Glycerol-3-phosphate 1-O-acyltransferase Cell membrane%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor%2C but not acyl-CoA or acyl-ACP%3B Belongs to the PlsY family%3B KEGG: bli:BL02954 glycerol-3-phosphate acyltransferase PlsY gene gene1445 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01446 S100141_01447 S100141_01447 S100141_01447 1312724 1313137 + uncharacterized protein gene gene1446 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01447 S100141_01448 S100141_01448 parE parE 1313455 1315428 + DNA topoisomerase 4 subunit ATP-binding%3B DNA-binding%3B Isomerase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Topoisomerase%3B Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule%3B Belongs to the type II topoisomerase family. ParE type 2 subfamily%3B Contains 1 Toprim domain%3B KEGG: bli:BL01186 topoisomerase IV subunit B%3B Other isomerases gene gene1447 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01448 S100141_01449 S100141_01449 parC parC 1315433 1317856 + DNA topoisomerase 4 subunit Cell membrane%3B Cytoplasm%3B DNA-binding%3B Isomerase%3B Membrane%3B Topoisomerase%3B Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule%3B Belongs to the topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily%3B KEGG: bsu:BSU18100 topoisomerase IV subunit A%3B Other isomerases gene gene1448 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01449 S100141_01450 S100141_01450 S100141_01450 1318158 1319249 - Arabinose metabolism transcriptional repressor Cytoplasm%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcriptional repressor of the arabinose utilization genes%3B Contains 1 HTH gntR-type DNA-binding domain gene gene1449 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01450 S100141_01451 S100141_01451 araB araB 1319602 1321209 + Ribulokinase KEGG: lme:LEUM_0854 L-ribulokinase gene gene1450 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01451 S100141_01452 S100141_01452 araD araD 1321223 1321918 + L-ribulose-5-phosphate 4-epimerase Isomerase%3B Metal-binding%3B Zinc%3B Catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate. Is involved in the anaerobic L-ascorbate utilization (By similarity)%3B Belongs to the aldolase class II family. AraD/FucA subfamily%3B KEGG: ype:YPO2230 L-ribulose-5-phosphate 4-epimerase gene gene1451 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01452 S100141_01453 S100141_01453 araA araA 1321974 1323398 + L-arabinose isomerase Arabinose catabolism%3B Carbohydrate metabolism%3B Isomerase%3B Manganese%3B Metal-binding%3B Catalyzes the conversion of L-arabinose to L-ribulose%3B Belongs to the arabinose isomerase family%3B KEGG: bli:BL01182 L-arabinose isomerase gene gene1452 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01453 S100141_01454 S100141_01454 S100141_01454 1323682 1325076 + D-xylose-proton symporter Cell membrane%3B Membrane%3B Sugar transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Uptake of D-xylose across the boundary membrane with the concomitant transport of protons into the cell (symport system)%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene1453 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01454 S100141_01455 S100141_01455 S100141_01455 1325647 1326429 - 3-oxoacyl-[acyl-carrier-protein] reductase Cytoplasm%3B NAD%3B Oxidoreductase%3B Stress response%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: ppb:PPUBIRD1_2441 3-oxoacyl-(acyl-carrier protein) reductase gene gene1454 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01455 S100141_01456 S100141_01456 S100141_01456 1326753 1326878 - hypothetical protein gene gene1455 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01456 S100141_01457 S100141_01457 S100141_01457 1326907 1327251 - hypothetical protein gene gene1456 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01457 S100141_01458 S100141_01458 S100141_01458 1327579 1328991 + Amino-acid carrier protein AlsT Amino-acid transport%3B Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the sodium:alanine (SAF) symporter family gene gene1457 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01458 S100141_01459 S100141_01459 S100141_01459 1329036 1329380 - hypothetical protein gene gene1458 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01459 S100141_01460 S100141_01460 narI narI 1329493 1330179 - Nitrate reductase Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Nitrate assimilation%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B KEGG: bli:BL01175 nitrate reductase gamma subunit gene gene1459 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01460 S100141_01461 S100141_01461 S100141_01461 1330176 1330718 - putative nitrate reductase molybdenum cofactor assembly chaperone NarJ Chaperone%3B Cytoplasm%3B Nitrate assimilation%3B Chaperone required for proper molybdenum cofactor insertion and final assembly of the membrane-bound respiratory nitrate reductase%3B Belongs to the NarJ/NarW family gene gene1460 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01461 S100141_01462 S100141_01462 narH narH 1330737 1332206 - Nitrate reductase 3Fe-4S%3B 4Fe-4S%3B Cell membrane%3B Electron transport%3B Iron%3B Iron-sulfur%3B Membrane%3B Metal-binding%3B Nitrate assimilation%3B Oxidoreductase%3B Repeat%3B Transport%3B Contains 3 4Fe-4S ferredoxin-type domains%3B KEGG: sod:Sant_0172 nitrate reductase beta subunit%3B overlaps another CDS with the same product name gene gene1461 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01462 S100141_01463 S100141_01463 narG narG 1332196 1335882 - Nitrate reductase 4Fe-4S%3B Cell membrane%3B Electron transport%3B Iron%3B Iron-sulfur%3B Membrane%3B Metal-binding%3B Molybdenum%3B Nitrate assimilation%3B Oxidoreductase%3B Transport%3B The alpha chain is the actual site of nitrate reduction. Belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: bsu:BSU37280 nitrate reductase alpha subunit%3B overlaps another CDS with the same product name gene gene1462 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01463 S100141_01464 S100141_01464 S100141_01464 1336057 1337298 - hypothetical protein gene gene1463 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01464 S100141_01465 S100141_01465 S100141_01465 1337295 1337537 - hypothetical protein gene gene1464 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01465 S100141_01466 S100141_01466 S100141_01466 1337626 1338729 - Coenzyme PQQ synthesis protein 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B PQQ biosynthesis%3B S-adenosyl-L-methionine%3B Belongs to the radical SAM superfamily. PqqE family gene gene1465 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01466 S100141_01467 S100141_01467 S100141_01467 1338844 1339311 - putative transcription regulator ArfM Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Activates%2C in anaerobic conditions%2C the transcription of the fermentative operons lctEP and alsDS%2C of the hmp gene encoding a flavohemoglobin-like protein%2C the nitrite reductase operon nasDE and the heme biosynthesis genes hemN and hemZ gene gene1466 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01467 S100141_01468 S100141_01468 S100141_01468 1339461 1340183 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B To H. influenzae HI_1626 gene gene1467 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01468 S100141_01469 S100141_01469 S100141_01469 1340229 1340942 - Anaerobic regulatory protein 4Fe-4S%3B Activator%3B Cytoplasm%3B DNA-binding%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Transcription%3B Transcription regulation%3B It is involved in the activation of genes necessary for anaerobic respiration. Contains 1 cyclic nucleotide-binding domain%3B Contains 1 HTH crp-type DNA-binding domain gene gene1468 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01469 S100141_01470 S100141_01470 S100141_01470 1341088 1342272 - Nitrite extrusion protein Cell membrane%3B Membrane%3B Nitrate assimilation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in excretion of nitrite produced by the dissimilatory reduction of nitrate. Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2. A. 1. 8) family gene gene1469 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01470 S100141_01471 S100141_01471 S100141_01471 1342494 1342733 + hypothetical protein gene gene1470 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01471 S100141_01472 S100141_01472 S100141_01472 1342696 1343445 + CRP-like cAMP-activated global transcriptional regulator Activator%3B cAMP%3B cAMP-binding%3B DNA-binding%3B Kinase%3B Nucleotide-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Transferase%3B Global transcriptional regulator that complexes with cAMP and binds to specific DNA promoter sites%2C causing DNA- bending%2C to regulate transcription. cAMP improves binding to specific DNA sequences%2C probably by altering protein conformation. Involved in the regulation of gntP and gntK genes%2C which are involved in gluconate metabolism (PubMed:16385030). May form dimers which bind to the aceB promoter region in the presence of cAMP and repress the glyoxylate bypass genes (PubMed:15150232). It could be a positive regulator of rpf2 gene expression during growth on acetate as the sole carbon source%2C however because the cytosolic cAMP level is elevated in the presence of glucose and low upon growth on acetate%2C it is conceivable that it is unable to function as an activator under acetate conditions (PubMed:18355281)%3B Contains 1 cyclic nucleotide-binding domain%3B Contains 1 HTH crp-type DNA-binding domain gene gene1471 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01472 S100141_01473 S100141_01473 norB norB 1343602 1345956 + Nitric-oxide reductase (cytochrome c) Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Respiratory chain%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Component of the anaerobic respiratory chain that transforms nitrate to dinitrogen (denitrification). NorB is the catalytic subunit of the enzyme complex. Shows proton pump activity across the membrane in denitrifying bacterial cells. The mononitrogen reduction is probably coupled to electron transport phosphorylation (By similarity)%3B Belongs to the heme-copper respiratory oxidase family%3B KEGG: bli:BL01473 nitric oxide reductase subunit B gene gene1472 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01473 S100141_01474 S100141_01474 S100141_01474 1346001 1346714 - Iron-sulfur cluster repair protein YtfE Cytoplasm%3B Iron%3B Metal-binding%3B Stress response%3B Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions%3B Belongs to the RIC family. YtfE subfamily gene gene1473 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01474 S100141_01475 S100141_01475 S100141_01475 1346880 1347251 + UPF0713 protein YngL Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0713 family gene gene1474 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01475 S100141_01476 S100141_01476 S100141_01476 1347620 1349224 + Cellulase Carbohydrate metabolism%3B Cellulose degradation%3B Glycosidase%3B Hydrolase%3B Polysaccharide degradation%3B Signal%3B Belongs to the glycosyl hydrolase 5 (cellulase A) family%3B Contains 1 CBM3 (carbohydrate binding type-3) domain%3B KEGG: bld:BLi02088 endoglucanase gene gene1475 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01476 S100141_01477 S100141_01477 S100141_01477 1349323 1349580 + uncharacterized protein Phosphoprotein. gene gene1476 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01477 S100141_01478 S100141_01478 S100141_01478 1349607 1350113 + Ribosomal-protein-alanine N-acetyltransferase Contains 1 N-acetyltransferase domain%3B KEGG: pat:Patl_0113 ribosomal-protein-alanine N-acetyltransferase gene gene1477 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01478 S100141_01479 S100141_01479 S100141_01479 1350659 1351795 - 1-alkyl-2-acetylglycerophosphocholine esterase KEGG: cel:CELE_W03G9. 6 platelet-activating factor acetylhydrolase gene gene1478 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01479 S100141_01480 S100141_01480 S100141_01480 1352518 1353435 - Thioredoxin-disulfide reductase Disulfide bond%3B FAD%3B Flavoprotein%3B Glycoprotein%3B NADP%3B Oxidoreductase%3B Redox-active center%3B Secreted%3B Signal%3B Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: cgl:NCgl0663 thioredoxin reductase (NADPH) gene gene1479 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01480 S100141_01481 S100141_01481 S100141_01481 1353488 1354378 - hypothetical protein gene gene1480 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01481 S100141_01482 S100141_01482 S100141_01482 1354483 1354908 - Protein rrf2 DNA-binding%3B Contains 1 HTH rrf2-type DNA-binding domain gene gene1481 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01482 S100141_01483 S100141_01483 S100141_01483 1355299 1356705 - uncharacterized protein Repeat%3B Secreted%3B Signal%3B Contains 8 PbH1 repeats gene gene1482 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01483 S100141_01484 S100141_01484 S100141_01484 1356843 1358159 - Branched-chain amino acid transport system carrier protein BrnQ Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Component of the transport system for branched-chain amino acids (leucine%2C isoleucine and valine) Which is coupled to a proton motive force%3B Belongs to the branched chain amino acid transporter family gene gene1483 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01484 S100141_01485 S100141_01485 yahK yahK 1358721 1359779 - putative formaldehyde dehydrogenase AdhA Metal-binding%3B Oxidoreductase%3B Stress response%3B Zinc%3B Functions in the protection against aldehyde-stress%3B Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: bli:BL05196 uncharacterized zinc-type alcohol dehydrogenase-like protein%3B Oxidoreductases gene gene1484 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01485 S100141_01486 S100141_01486 S100141_01486 1359985 1360380 + putative HTH-type transcriptional regulator DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH merR-type DNA-binding domain gene gene1485 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01486 S100141_01487 S100141_01487 S100141_01487 1360407 1360670 - Phosphocarrier protein HPr Cytoplasm%3B Kinase%3B Phosphoprotein%3B Phosphotransferase system%3B Serine/threonine-protein kinase%3B Sugar transport%3B Transcription%3B Transcription regulation%3B Transferase%3B Transport%3B General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the permease (enzymes II/III). P-Ser-HPr interacts with the catabolite control protein A (CcpA)%2C forming a complex that binds to DNA at the catabolite response elements cre%2C operator sites preceding a large number of catabolite-regulated genes. Thus%2C P-Ser-HPr is a corepressor in carbon catabolite repression (CCR)%2C a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion%2C in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity)%3B Belongs to the HPr family%3B Contains 1 HPr domain gene gene1486 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01487 S100141_01488 S100141_01488 S100141_01488 1360868 1361905 - N-acetylphosphatidylethanolamine-hydrolyzing phospholipase D Acetylation%3B Hydrolase%3B Lipid degradation%3B Lipid metabolism%3B Membrane%3B Metal-binding%3B Phospholipid degradation%3B Phospholipid metabolism%3B Polymorphism%3B Zinc%3B Hydrolyzes N-acyl-phosphatidylethanolamines (NAPEs) to produce N-acylethanolamines (NAEs) and phosphatidic acid. Responsible for the generation of anandamide (N- arachidonoylethanolamine)%2C the ligand of cannabinoid and vanilloid receptors (By similarity)%3B Belongs to the NAPE-PLD family%3B KEGG: hmg:100205873 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D gene gene1487 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01488 S100141_01489 S100141_01489 S100141_01489 1362123 1362575 - hypothetical protein gene gene1488 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01489 S100141_01490 S100141_01490 paaF paaF 1362646 1363707 - Enoyl-CoA hydratase Lyase%3B Belongs to the enoyl-CoA hydratase/isomerase family%3B KEGG: ngl:RG1141_CH32070 enoyl-CoA hydratase gene gene1489 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01490 S100141_01491 S100141_01491 fadB fadB 1363723 1364508 - Enoyl-CoA hydratase Fatty acid metabolism%3B Lipid degradation%3B Lipid metabolism%3B Lyase%3B Involved in the degradation of long-chain fatty acids. Belongs to the enoyl-CoA hydratase/isomerase family%3B KEGG: blh:BaLi_c21690 enoyl-CoA hydratase gene gene1490 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01491 S100141_01492 S100141_01492 mmsA mmsA 1364591 1366045 - Malonate-semialdehyde dehydrogenase (acetylating) NAD%3B Oxidoreductase%3B Converts malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA%2C respectively%3B Belongs to the aldehyde dehydrogenase family. IolA subfamily%3B KEGG: bli:BL00293 malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase gene gene1491 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01492 S100141_01493 S100141_01493 garR garR 1366064 1366951 - 2-hydroxy-3-oxopropionate reductase Branched-chain amino acid catabolism%3B Mitochondrion%3B NAD%3B Oxidoreductase%3B Transit peptide%3B Belongs to the 3-hydroxyisobutyrate dehydrogenase family%3B KEGG: pae:PA1500 2-hydroxy-3-oxopropionate reductase gene gene1492 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01493 S100141_01494 S100141_01494 S100141_01494 1366967 1368682 - putative acyl-CoA dehydrogenase FAD%3B Fatty acid metabolism%3B Flavoprotein%3B Lipid degradation%3B Lipid metabolism%3B Oxidoreductase%3B Involved in the degradation of long-chain fatty acids. Belongs to the acyl-CoA dehydrogenase family%3B KEGG: bli:BL00291 null%3B With other acceptors gene gene1493 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01494 S100141_01495 S100141_01495 manA manA 1369140 1370093 - Mannose-6-phosphate isomerase Isomerase%3B Metal-binding%3B Zinc%3B Belongs to the mannose-6-phosphate isomerase type 1 family%3B KEGG: bli:BL00290 mannose-6-phosphate isomerase gene gene1494 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01495 S100141_01496 S100141_01496 fruA fruA 1370112 1372055 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Kinase%3B Membrane%3B Phosphotransferase system%3B Repeat%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport. Contains 2 PTS EIIB type-2 domains%3B Contains 1 PTS EIIC type-2 domain%3B KEGG: pse:NH8B_1236 PTS system%2C fructose-specific IIB component gene gene1495 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01496 S100141_01497 S100141_01497 S100141_01497 1372458 1372799 + hypothetical protein gene gene1496 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01497 S100141_01498 S100141_01498 S100141_01498 1373278 1373448 - hypothetical protein gene gene1497 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01498 S100141_01499 S100141_01499 S100141_01499 1373603 1373875 - hypothetical protein gene gene1498 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01499 S100141_01500 S100141_01500 S100141_01500 1373990 1375933 - Transcriptional regulator ManR Activator%3B DNA-binding%3B Kinase%3B Phosphoprotein%3B Repeat%3B Transcription%3B Transcription regulation%3B Transferase%3B Positively regulates the expression of the mannose operon that consists of three genes%2C manP%2C manA%2C and yjdF%2C which are responsible for the transport and utilization of mannose. Also activates its own expression%3B Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains%3B Contains 1 PTS EIIA type-2 domain%3B Contains 1 PTS EIIB type-2 domain gene gene1499 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01500 S100141_01501 S100141_01501 S100141_01501 1376239 1376895 - hypothetical protein gene gene1500 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01501 S100141_01502 S100141_01502 S100141_01502 1376879 1377757 - Energy-coupling factor transporter ATP-binding protein EcfA1 ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the ABC transporter superfamily. Energy- coupling factor EcfA family%3B Contains 1 ABC transporter domain gene gene1501 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01502 S100141_01503 S100141_01503 S100141_01503 1377760 1378134 - putative HTH-type transcriptional regulator YhcF DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH gntR-type DNA-binding domain gene gene1502 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01503 S100141_01504 S100141_01504 S100141_01504 1378424 1379275 - putative oxidoreductase NAD%3B Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bha:BH0707 null%3B Oxidoreductases gene gene1503 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01504 S100141_01505 S100141_01505 S100141_01505 1379313 1380377 - Mannonate dehydratase Iron%3B Lyase%3B Manganese%3B Catalyzes the dehydration of D-mannonate%3B Belongs to the mannonate dehydratase family%3B KEGG: bur:Bcep18194_B1358 mannonate dehydratase gene gene1504 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01505 S100141_01506 S100141_01506 S100141_01506 1380628 1383036 - Alpha-glucosidase Carbohydrate metabolism%3B Cell wall biogenesis/degradation%3B Glycoprotein%3B Glycosidase%3B Hydrolase%3B Polysaccharide degradation%3B Secreted%3B Signal%3B Glucosidase involved in the degradation of cellulosic biomass. Has both alpha- and beta-glucosidase activity (By similarity)%3B Belongs to the glycosyl hydrolase 31 family%3B KEGG: bli:BL00280 alpha-glucosidase gene gene1505 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01506 S100141_01507 S100141_01507 S100141_01507 1383056 1384351 - uncharacterized protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the YiaN/YgiK family gene gene1506 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01507 S100141_01508 S100141_01508 S100141_01508 1384390 1384905 - Putative TRAP transporter small permease protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the TRAP transporter small permease family gene gene1507 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01508 S100141_01509 S100141_01509 S100141_01509 1384956 1385966 - C4-dicarboxylate-binding protein DctB Secreted%3B Signal%3B Sugar transport%3B Transport%3B Part of the binding-protein-dependent transport system for uptake of C4-dicarboxylates. Responsible for growth on fumarate and succinate but not malate. Is not directly involved in C4-dicarboxylate uptake%2C but plays a sensory role in the DctS/DctR two-component system which regulates the expression of the dctA C4-dicarboxylate transporter%3B Belongs to the bacterial solute-binding protein 7 family gene gene1508 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01509 S100141_01510 S100141_01510 S100141_01510 1386425 1387435 + Catabolite control protein A Activator%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA)%2C which ensures optimal energy usage under diverse conditions%3B Contains 1 HTH lacI-type DNA-binding domain gene gene1509 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01510 S100141_01511 S100141_01511 arsC arsC 1387650 1388069 - Arsenate reductase (glutaredoxin) Arsenical resistance%3B Disulfide bond%3B Hydrolase%3B Oxidoreductase%3B Redox-active center%3B Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins%2C low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances%3B Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family%3B KEGG: bsr:I33_0599 arsenate reductase gene gene1510 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01511 S100141_01512 S100141_01512 S100141_01512 1388092 1389387 - Arsenical pump membrane protein Arsenical resistance%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in arsenical resistance. Thought to form the channel of an arsenite pump. Belongs to the ArsB family gene gene1511 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01512 S100141_01513 S100141_01513 S100141_01513 1389511 1389858 - HTH-type transcriptional repressor AseR Cytoplasm%3B DNA-binding%3B Metal-binding%3B Metal-thiolate cluster%3B Repressor%3B Transcription%3B Transcription regulation%3B Metal-responsive transcriptional regulator that represses transcription of the aseR-ydfA operon by binding specifically to its promoter. Binding of arsenite or antimonite causes the repressor to dissociate from the DNA%3B Contains 1 HTH arsR-type DNA-binding domain gene gene1512 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01513 S100141_01514 S100141_01514 S100141_01514 1390347 1390940 - uncharacterized protein gene gene1513 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01514 S100141_01515 S100141_01515 S100141_01515 1391062 1391787 + hypothetical protein gene gene1514 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01515 S100141_01516 S100141_01516 S100141_01516 1392010 1392867 - putative glucose uptake protein Cell membrane%3B Membrane%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the uptake of glucose%3B Belongs to the GRP transporter (TC 2. A. 7. 5) family gene gene1515 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01516 S100141_01517 S100141_01517 S100141_01517 1392989 1394176 - N-acetylmuramoyl-L-alanine amidase Signal%3B Belongs to the UPF0748 family%3B KEGG: esr:ES1_16340 N-acetylmuramoyl-L-alanine amidase gene gene1516 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01517 S100141_01518 S100141_01518 S100141_01518 1394594 1394947 - Oligoribonuclease NrnB Cytoplasm%3B Exonuclease%3B Hydrolase%3B Nuclease%3B Degrades RNA oligonucleotides with a length of 5 nucleotides in a 3'- to 5'-direction. Less active on shorter RNA oligonucleotides and on those with a length of 24 nucleotides. Prefers RNA oligonucleotides containing adenines rather than cytosines gene gene1517 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01518 S100141_01519 S100141_01519 S100141_01519 1394988 1395311 - Oligoribonuclease NrnB Cytoplasm%3B Exonuclease%3B Hydrolase%3B Nuclease%3B Degrades RNA oligonucleotides with a length of 5 nucleotides in a 3'- to 5'-direction. Less active on shorter RNA oligonucleotides and on those with a length of 24 nucleotides. Prefers RNA oligonucleotides containing adenines rather than cytosines gene gene1518 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01519 S100141_01520 S100141_01520 pflA pflA 1395466 1396224 - [Formate-C-acetyltransferase]-activating enzyme 4Fe-4S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase%3B S-adenosyl-L-methionine%3B Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical%2C using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. Belongs to the organic radical-activating enzymes family%3B KEGG: bli:BL01864 pyruvate formate lyase activating enzyme gene gene1519 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01520 S100141_01521 S100141_01521 pflD pflD 1396282 1398507 - Formate C-acetyltransferase Acyltransferase%3B Carbohydrate metabolism%3B Cytoplasm%3B Glucose metabolism%3B Organic radical%3B Transferase%3B Contains 1 glycine radical domain%3B Contains 1 PFL domain%3B KEGG: bli:BL01863 formate C-acetyltransferase gene gene1520 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01521 S100141_01522 S100141_01522 dacB dacB 1399005 1400474 - D-alanyl-D-alanine carboxypeptidase DacC Cell cycle%3B Cell division%3B Cell shape%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Peptidoglycan synthesis%3B Secreted%3B Signal%3B Catalyzes DD-carboxypeptidase and transpeptidation reactions%3B Belongs to the peptidase S13 family%3B KEGG: bli:BL01997 D-alanyl-D-alanine carboxypeptidase / D-alanyl-D-alanine-endopeptidase (penicillin-binding protein 4)%3B Serine-type D-Ala-D-Ala carboxypeptidase gene gene1521 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01522 S100141_01523 S100141_01523 S100141_01523 1400721 1401404 - UPF0702 transmembrane protein YetF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0702 family gene gene1522 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01523 S100141_01524 S100141_01524 S100141_01524 1401525 1403018 - Cardiolipin synthase Cell membrane%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Repeat%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol%3B Belongs to the phospholipase D family. Cardiolipin synthase subfamily%3B Contains 2 PLD phosphodiesterase domains%3B KEGG: ban:BA_2054 cardiolipin synthase%3B Transferases for other substituted phosphate groups gene gene1523 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01524 S100141_01525 S100141_01525 S100141_01525 1403371 1403781 - UPF0702 transmembrane protein YetF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0702 family gene gene1524 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01525 S100141_01526 S100141_01526 S100141_01526 1403994 1404854 - UPF0702 transmembrane protein YetF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0702 family gene gene1525 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01526 S100141_01527 S100141_01527 S100141_01527 1404884 1405090 - hypothetical protein gene gene1526 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01527 S100141_01528 S100141_01528 S100141_01528 1405102 1405452 - Stage V sporulation protein AEB Sporulation. gene gene1527 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01528 S100141_01529 S100141_01529 S100141_01529 1405449 1406468 - Stage V sporulation protein AD Sporulation. gene gene1528 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01529 S100141_01530 S100141_01530 S100141_01530 1406468 1406881 - Stage V sporulation protein AC Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix. gene gene1529 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01530 S100141_01531 S100141_01531 S100141_01531 1406941 1407273 + hypothetical protein gene gene1530 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01531 S100141_01532 S100141_01532 S100141_01532 1407243 1408103 + putative transposase-like protein DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene1531 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01532 S100141_01533 S100141_01533 S100141_01533 1408170 1409060 - hypothetical protein gene gene1532 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01533 S100141_01534 S100141_01534 S100141_01534 1409129 1409335 - hypothetical protein gene gene1533 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01534 S100141_01535 S100141_01535 S100141_01535 1409743 1410195 - Spore germination protein XC Cell membrane%3B Germination%3B Lipoprotein%3B Membrane%3B Palmitate%3B Plasmid%3B Signal%3B Virulence%3B May allow B. anthracis to germinate within phagocytic cells and therefore involved in virulence. Belongs to the GerABKC lipoprotein family gene gene1534 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01535 S100141_01536 S100141_01536 S100141_01536 1410210 1411223 - Spore germination protein Cell membrane%3B Germination%3B Membrane%3B Plasmid%3B Transmembrane%3B Transmembrane helix%3B Virulence%3B May allow B. anthracis to germinate within phagocytic cells and therefore involved in virulence. Belongs to the GerABKA family gene gene1535 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01536 S100141_01537 S100141_01537 S100141_01537 1411177 1411479 - N-acetylmuramoyl-L-alanine amidase Cell wall%3B Cell wall biogenesis/degradation%3B Competence%3B Hydrolase%3B Metal-binding%3B Repeat%3B Secreted%3B Sporulation%3B Zinc%3B Autolysins are involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella - in particular of its basal body - and sporulation. CwlC is able to hydrolyze type A cell walls such as B. subtilis. Its main function is to lyze the mother cell wall peptidoglycan%2C playing a role during sporulation%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B Contains 1 SPOR domain%3B KEGG: bsu:BSU17410 N-acetylmuramoyl-L-alanine amidase gene gene1536 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01537 S100141_01538 S100141_01538 S100141_01538 1411841 1412293 + hypothetical protein gene gene1537 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01538 S100141_01539 S100141_01539 S100141_01539 1412353 1413255 + transposase DNA recombination%3B DNA-binding%3B Plasmid%3B Transposable element%3B Transposition%3B Transposase for transposon Tn1546. Required for transposition of transposon Tn1546. Belongs to the transposase 7 family gene gene1538 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01539 S100141_01540 S100141_01540 S100141_01540 1413232 1414026 - hypothetical protein gene gene1539 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01540 S100141_01541 S100141_01541 S100141_01541 1414108 1414419 - NADH dehydrogenase FAD%3B Flavoprotein%3B Oxidoreductase%3B Belongs to the NADH dehydrogenase family%3B KEGG: bsu:BSU12290 NADH dehydrogenase gene gene1540 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01541 S100141_01542 S100141_01542 S100141_01542 1414497 1415285 - NADH dehydrogenase FAD%3B Flavoprotein%3B Oxidoreductase%3B Belongs to the NADH dehydrogenase family%3B KEGG: bsu:BSU12290 NADH dehydrogenase gene gene1541 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01542 S100141_01543 S100141_01543 S100141_01543 1415322 1415756 - uncharacterized protein gene gene1542 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01543 S100141_01544 S100141_01544 S100141_01544 1415708 1416031 - hypothetical protein gene gene1543 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01544 S100141_01545 S100141_01545 S100141_01545 1416166 1416396 - Glucose-6-phosphate isomerase KEGG: bbe:BBR47_08920 glucose-6-phosphate isomerase gene gene1544 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01545 S100141_01546 S100141_01546 S100141_01546 1416489 1416713 + uncharacterized protein Coiled coil. gene gene1545 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01546 S100141_01547 S100141_01547 acsS acsS 1416795 1418747 - Acetate--CoA ligase Acetylation%3B ATP-binding%3B Ligase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Catalyzes the conversion of acetate into acetyl-CoA (AcCoA)%2C an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction%2C AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction%2C it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA%2C forming the product AcCoA%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bli:BL01993 acetyl-CoA synthetase gene gene1546 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01547 S100141_01548 S100141_01548 pccB pccB 1418778 1420307 - Propionyl-CoA carboxylase ATP-binding%3B Ligase%3B Nucleotide-binding%3B Belongs to the AccD/PCCB family%3B Contains 1 carboxyltransferase domain%3B KEGG: obt:OPIT5_14445 propionyl-CoA carboxylase beta chain gene gene1547 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01548 S100141_01549 S100141_01549 S100141_01549 1420328 1421110 - Enoyl-CoA hydratase Lyase%3B Belongs to the enoyl-CoA hydratase/isomerase family%3B KEGG: lan:Lacal_1125 enoyl-CoA hydratase gene gene1548 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01549 S100141_01550 S100141_01550 hmgL hmgL 1421130 1422041 - Hydroxymethylglutaryl-CoA lyase Lyase%3B Metal-binding%3B Involved in the catabolism of branched amino acids such as leucine%3B Belongs to the HMG-CoA lyase family%3B KEGG: bli:BL01990 hydroxymethylglutaryl-CoA lyase gene gene1549 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01550 S100141_01551 S100141_01551 S100141_01551 1422059 1422271 - Biotin/lipoyl attachment protein Biotin%3B Lipoyl%3B Contains 1 biotinyl-binding domain gene gene1550 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01551 S100141_01552 S100141_01552 accC accC 1422289 1423629 - Acetyl-CoA carboxylase ATP-binding%3B Biotin%3B Ligase%3B Magnesium%3B Nucleotide-binding%3B Contains 1 ATP-grasp domain%3B Contains 1 biotin carboxylation domain%3B KEGG: wgl:WIGMOR_0138 acetyl-CoA carboxylase%2C biotin carboxylase subunit gene gene1551 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01552 S100141_01553 S100141_01553 S100141_01553 1423672 1425309 - Putative acyl-CoA synthetase YngI ATP-binding%3B Ligase%3B Nucleotide-binding%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bli:BL01987 fatty-acyl-CoA synthase%3B Acid--thiol ligases gene gene1552 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01553 S100141_01554 S100141_01554 S100141_01554 1425341 1426501 - Short-chain acyl-CoA dehydrogenase FAD%3B Flavoprotein%3B Oxidoreductase%3B Belongs to the acyl-CoA dehydrogenase family%3B KEGG: oih:OB1695 butyryl-CoA dehydrogenase gene gene1553 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01554 S100141_01555 S100141_01555 nqo1 nqo1 1426732 1427292 + NAD(P)H dehydrogenase (quinone) Cell inner membrane%3B Cell membrane%3B Flavoprotein%3B FMN%3B Membrane%3B NAD%3B Oxidoreductase%3B Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity%2C but this enzymatic activity is not required for activation of KefC%3B Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily%3B KEGG: cvi:CV_0290 NAD(P)H dehydrogenase (quinone) gene gene1554 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01555 S100141_01556 S100141_01556 S100141_01556 1427334 1427684 - putative HTH-type transcriptional regulator DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH hxlR-type DNA-binding domain gene gene1555 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01556 S100141_01557 S100141_01557 S100141_01557 1427896 1429167 - Glutamate-5-semialdehyde dehydrogenase Amino-acid biosynthesis%3B Cytoplasm%3B NADP%3B Oxidoreductase%3B Proline biosynthesis%3B Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate%3B Belongs to the gamma-glutamyl phosphate reductase family%3B KEGG: bli:BL01984 glutamate-5-semialdehyde dehydrogenase gene gene1556 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01557 S100141_01558 S100141_01558 S100141_01558 1429193 1430314 - Glutamate 5-kinase Amino-acid biosynthesis%3B ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Proline biosynthesis%3B Transferase%3B Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate%3B Belongs to the glutamate 5-kinase family%3B Contains 1 PUA domain%3B KEGG: bli:BL01983 glutamate 5-kinase gene gene1557 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01558 S100141_01559 S100141_01559 S100141_01559 1430353 1431153 - Pyrroline-5-carboxylate reductase Amino-acid biosynthesis%3B Cytoplasm%3B NADP%3B Oxidoreductase%3B Proline biosynthesis%3B Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline%3B Belongs to the pyrroline-5-carboxylate reductase family%3B KEGG: bsu:BSU18480 pyrroline-5-carboxylate reductase gene gene1558 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01559 S100141_01560 S100141_01560 S100141_01560 1431401 1431604 - hypothetical protein gene gene1559 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01560 S100141_01561 S100141_01561 S100141_01561 1431555 1431899 - UPF0702 transmembrane protein YetF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0702 family%3B overlaps another CDS with the same product name gene gene1560 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01561 S100141_01562 S100141_01562 S100141_01562 1431890 1432231 - UPF0702 transmembrane protein YetF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0702 family%3B overlaps another CDS with the same product name gene gene1561 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01562 S100141_01563 S100141_01563 S100141_01563 1432534 1433673 - Sulfate permease CysP Cell membrane%3B Membrane%3B Sulfate transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the import of sulfate%3B Belongs to the inorganic phosphate transporter (PiT) (TC 2. A. 20) family gene gene1562 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01563 S100141_01564 S100141_01564 S100141_01564 1433688 1434398 - Phosphoadenylyl-sulfate reductase (thioredoxin) Cytoplasm%3B Oxidoreductase%3B Reduction of activated sulfate into sulfite%3B Belongs to the PAPS reductase family. CysH subfamily%3B KEGG: bli:BL01979 phosphoadenosine phosphosulfate reductase gene gene1563 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01564 S100141_01565 S100141_01565 comA comA 1434946 1435710 + Phosphosulfolactate synthase Coenzyme M biosynthesis%3B Lyase%3B Catalyzes the addition of sulfite to phosphoenolpyruvate (PEP) to yield (2R)-phospho-3-sulfolactate (PSL)%3B Belongs to the phosphosulfolactate synthase family%3B KEGG: bli:BL02005 phosphosulfolactate synthase gene gene1564 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01565 S100141_01566 S100141_01566 S100141_01566 1435728 1436351 - UPF0750 membrane protein YitE Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0750 family gene gene1565 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01566 S100141_01567 S100141_01567 S100141_01567 1436445 1437551 - Putative isomerase YitF Isomerase%3B Magnesium%3B Metal-binding%3B Belongs to the mandelate racemase/muconate lactonizing enzyme family%3B KEGG: bss:BSUW23_05560 D-galactarolactone cycloisomerase%3B Intramolecular lyases gene gene1566 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01567 S100141_01568 S100141_01568 S100141_01568 1437568 1438812 - putative MFS-type transporter YitG Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene1567 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01568 S100141_01569 S100141_01569 dpm1 dpm1 1438884 1439891 - Dolichyl-phosphate beta-D-mannosyltransferase Cell membrane%3B Glycosyltransferase%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Belongs to the glycosyltransferase 2 family%3B KEGG: fco:FCOL_06185 dolichol-phosphate mannosyltransferase gene gene1568 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01569 S100141_01570 S100141_01570 S100141_01570 1439914 1441629 - putative membrane protein YkoS Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1569 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01570 S100141_01571 S100141_01571 S100141_01571 1441755 1441940 - hypothetical protein gene gene1570 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01571 S100141_01572 S100141_01572 gltD gltD 1442163 1443644 - Glutamate synthase (NADPH) Amino-acid biosynthesis%3B Glutamate biosynthesis%3B NADP%3B Oxidoreductase%3B Belongs to the glutamate synthase family%3B KEGG: rso:RSc2964 glutamate synthase (NADPH/NADH) small chain gene gene1571 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01572 S100141_01573 S100141_01573 gltB gltB 1443661 1448226 - Glutamate synthase (NADPH) 3Fe-4S%3B Amino-acid biosynthesis%3B FAD%3B Flavoprotein%3B FMN%3B Glutamate biosynthesis%3B Glutamine amidotransferase%3B Iron%3B Iron-sulfur%3B Metal-binding%3B NADP%3B Oxidoreductase%3B Belongs to the glutamate synthase family%3B Contains 1 glutamine amidotransferase type-2 domain%3B KEGG: bsu:BSU18450 glutamate synthase (NADPH/NADH) large chain gene gene1572 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01573 S100141_01574 S100141_01574 S100141_01574 1448375 1449277 + HTH-type transcriptional regulator BsdA Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Could be a positive regulator of bsdBCD expression in response to salicylic acid%3B Contains 1 HTH lysR-type DNA-binding domain gene gene1573 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01574 S100141_01575 S100141_01575 S100141_01575 1449415 1449627 + hypothetical protein gene gene1574 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01575 S100141_01576 S100141_01576 S100141_01576 1449683 1451608 - hypothetical protein gene gene1575 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01576 S100141_01577 S100141_01577 S100141_01577 1451742 1453316 + hypothetical protein gene gene1576 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01577 S100141_01578 S100141_01578 S100141_01578 1453456 1453929 + hypothetical protein gene gene1577 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01578 S100141_01579 S100141_01579 S100141_01579 1453926 1455653 + Putative export ATP-binding/permease protein ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of an ABC transporter complex. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP- binding domain (NBD) is responsible for energy generation (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene1578 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01579 S100141_01580 S100141_01580 S100141_01580 1455650 1457473 + Lipid A export ATP-binding/permease protein MsbA ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Lipid transport%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation%3B Belongs to the ABC transporter superfamily. Lipid exporter (TC 3. A. 1. 106) family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene1579 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01580 S100141_01581 S100141_01581 cypX cypX 1457708 1458922 + Pulcherriminic acid synthase Heme%3B Iron%3B Metal-binding%3B Monooxygenase%3B Oxidoreductase%3B Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds%2C including steroids%2C fatty acids%2C and xenobiotics. Belongs to the cytochrome P450 family%3B KEGG: pao:Pat9b_5697 pulcherriminic acid synthase gene gene1580 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01581 S100141_01582 S100141_01582 idnO idnO 1458971 1459687 - Gluconate 5-dehydrogenase Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: smw:SMWW4_v1c33960 gluconate 5-dehydrogenase gene gene1581 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01582 S100141_01583 S100141_01583 ppsA ppsA 1460327 1462660 + Pyruvate%2C water dikinase Transferase%3B Might catalyze the phosphorylation of pyruvate to phosphoenolpyruvate%3B Belongs to the PEP-utilizing enzyme family%3B KEGG: bsu:BSU18830 pyruvate%2C water dikinase gene gene1582 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01583 S100141_01584 S100141_01584 S100141_01584 1463135 1464559 + putative MFS-type transporter YvkA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily. TCR/Tet family gene gene1583 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01584 S100141_01585 S100141_01585 napA napA 1464706 1466745 + Nitrate reductase Iron%3B Iron-sulfur%3B Metal-binding%3B Molybdenum%3B Oxidoreductase%3B Belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: ccc:G157_05015 periplasmic nitrate reductase NapA gene gene1584 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01585 S100141_01586 S100141_01586 S100141_01586 1466785 1467261 - HTH-type transcriptional regulator MhqR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Negatively regulates mhqA%2C mhqED%2C mhqNOP%2C and azoR2 which may contribute to the degradation of aromatic compounds%3B Contains 1 HTH marR-type DNA-binding domain gene gene1585 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01586 S100141_01587 S100141_01587 S100141_01587 1467400 1468920 + putative MFS-type transporter YusP Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily. EmrB family%3B KEGG: nhe:NECHADRAFT_65858 DNA repair protein RAD50%3B Acting on acid anhydrides gene gene1586 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01587 S100141_01588 S100141_01588 S100141_01588 1468925 1470022 - Spore germination protein YndE Amino-acid transport%3B Cell membrane%3B Germination%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the germinative response to L-alanine. Could be an amino acid transporter (By similarity)%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2. A. 3. 9) family gene gene1587 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01588 S100141_01589 S100141_01589 S100141_01589 1470062 1470448 - Spore germination protein YndF Cell membrane%3B Germination%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B May be involved in spore germination%3B Belongs to the GerABKC lipoprotein family%3B overlaps another CDS with the same product name gene gene1588 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01589 S100141_01590 S100141_01590 S100141_01590 1470445 1471257 - Spore germination protein YndF Cell membrane%3B Germination%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B May be involved in spore germination%3B Belongs to the GerABKC lipoprotein family%3B overlaps another CDS with the same product name gene gene1589 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01590 S100141_01591 S100141_01591 S100141_01591 1471244 1472068 - Spore germination protein A2 Amino-acid transport%3B Cell membrane%3B Germination%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the germinative response to L-alanine. Could be an amino acid transporter. Forms a complex at the inner spore membrane which acts as a receptor for L-alanine%2C thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors%2C respectively)%2C but the response is improved in their presence. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2. A. 3. 9) family gene gene1590 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01591 S100141_01592 S100141_01592 S100141_01592 1472065 1472343 - Spore germination protein YndE Amino-acid transport%3B Cell membrane%3B Germination%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the germinative response to L-alanine. Could be an amino acid transporter (By similarity)%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2. A. 3. 9) family gene gene1591 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01592 S100141_01593 S100141_01593 S100141_01593 1472370 1473470 - Spore germination protein A2 Amino-acid transport%3B Cell membrane%3B Germination%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the germinative response to L-alanine. Could be an amino acid transporter. Forms a complex at the inner spore membrane which acts as a receptor for L-alanine%2C thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors%2C respectively)%2C but the response is improved in their presence. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2. A. 3. 9) family gene gene1592 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01593 S100141_01594 S100141_01594 S100141_01594 1473493 1475061 - putative membrane protein YndD Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the GerABKA family gene gene1593 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01594 S100141_01595 S100141_01595 znuC znuC 1475338 1477065 - Aliphatic sulfonates import ATP-binding protein SsuB ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3. A. 1. 17. 2) family%3B Contains 1 ABC transporter domain%3B KEGG: xbo:XBJ1_2227 zinc transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene1594 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01595 S100141_01596 S100141_01596 S100141_01596 1477505 1479490 + Methyl-accepting chemotaxis protein McpB Cell membrane%3B Chemotaxis%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpB is required for taxis towards asparagine%2C aspartate%2C glutamine%2C and histidine%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene1595 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01596 S100141_01597 S100141_01597 S100141_01597 1479536 1479868 - Protein CsaA Chaperone%3B Cytoplasm%3B Protein transport%3B RNA-binding%3B Translocation%3B Transport%3B tRNA-binding%3B Could serves as a molecular chaperone for exported proteins or alternatively acts by stabilizing the SecA protein. Contains 1 tRNA-binding domain gene gene1596 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01597 S100141_01598 S100141_01598 aprX aprX 1480091 1481419 + Serine protease AprX Cytoplasm%3B Hydrolase%3B Protease%3B Serine protease%3B Displays serine protease activity. Seems to have a broad substrate specificity%3B Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bli:BL00903 serine protease AprX%3B Serine endopeptidases gene gene1597 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01598 S100141_01599 S100141_01599 S100141_01599 1481471 1481881 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1598 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01599 S100141_01600 S100141_01600 S100141_01600 1481888 1482487 - hypothetical protein gene gene1599 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01600 S100141_01601 S100141_01601 S100141_01601 1482624 1483115 - putative HTH-type transcriptional regulator YvmB DNA-binding%3B Transcription%3B Transcription regulation%3B Involved in protein secretion. Contains 1 HTH marR-type DNA-binding domain gene gene1600 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01601 S100141_01602 S100141_01602 nadD nadD 1483259 1483690 + Nicotinate-nucleotide adenylyltransferase KEGG: bfi:CIY_18840 nicotinate-nucleotide adenylyltransferase gene gene1601 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01602 S100141_01603 S100141_01603 S100141_01603 1483937 1484422 - hypothetical protein gene gene1602 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01603 S100141_01604 S100141_01604 S100141_01604 1484453 1486099 - putative membrane protein YndJ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1603 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01604 S100141_01605 S100141_01605 S100141_01605 1486096 1486713 - uncharacterized protein gene gene1604 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01605 S100141_01606 S100141_01606 S100141_01606 1486715 1487614 - putative membrane protein YndG Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1605 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01606 S100141_01607 S100141_01607 S100141_01607 1487857 1488429 - putative HTH-type transcriptional regulator YobS DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH tetR-type DNA-binding domain gene gene1606 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01607 S100141_01608 S100141_01608 S100141_01608 1488437 1489150 - uncharacterized protein Hydrolase%3B Metal-binding%3B Zinc%3B Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family gene gene1607 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01608 S100141_01609 S100141_01609 S100141_01609 1489232 1489705 - Putative transcriptional regulator protein YobU gene gene1608 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01609 S100141_01610 S100141_01610 S100141_01610 1489702 1489983 - hypothetical protein gene gene1609 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01610 S100141_01611 S100141_01611 S100141_01611 1490037 1490972 - putative HTH-type transcriptional regulator YobV Cytoplasm%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH deoR-type DNA-binding domain gene gene1610 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01611 S100141_01612 S100141_01612 S100141_01612 1491176 1491673 + Protein csk22 Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix. gene gene1611 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01612 S100141_01613 S100141_01613 S100141_01613 1491712 1492044 - HTH-type transcriptional repressor CzrA Cytoplasm%3B DNA-binding%3B Metal-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Zinc%3B Metal-responsive transcriptional regulator that represses transcription of cadA and the czcD-trkA operon by binding specifically to their promoter. Binding of zinc causes the repressor to dissociate from the DNA%3B Contains 1 HTH arsR-type DNA-binding domain gene gene1612 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01613 S100141_01614 S100141_01614 S100141_01614 1492120 1492944 - uncharacterized protein gene gene1613 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01614 S100141_01615 S100141_01615 S100141_01615 1493109 1493351 - uncharacterized protein Phosphoprotein. gene gene1614 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01615 S100141_01616 S100141_01616 S100141_01616 1493504 1494841 + Low-affinity putrescine importer PlaP Amino-acid transport%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Putrescine importer%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene1615 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01616 S100141_01617 S100141_01617 S100141_01617 1494976 1495584 + putative membrane protein YocA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1616 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01617 S100141_01618 S100141_01618 capD capD 1495512 1496702 - UDP-glucose 4-epimerase Belongs to the polysaccharide synthase family%3B KEGG: yfr:AW19_2183 UDP-glucose 4-epimerase gene gene1617 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01618 S100141_01619 S100141_01619 S100141_01619 1496755 1497393 - hypothetical protein gene gene1618 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01619 S100141_01620 S100141_01620 S100141_01620 1497590 1498003 - hypothetical protein gene gene1619 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01620 S100141_01621 S100141_01621 waaG waaG 1498018 1499226 - N-acetyl-alpha-D-glucosaminyl L-malate synthase Glycosyltransferase%3B Nucleotide-binding%3B Transferase%3B Involved in bacillithiol (BSH) biosynthesis. Catalyzes the first step of the pathway%2C the formation of N- acetylglucosaminylmalate (GlcNAc-Mal) from UDP-N-acetylglucosamine (UDP-GlcNAc) and L-malate%3B Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: cko:CKO_05089 UDP-glucose:(heptosyl)LPS alpha-1%2C3-glucosyltransferase%3B Hexosyltransferases gene gene1620 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01621 S100141_01622 S100141_01622 S100141_01622 1499388 1499831 - uncharacterized protein gene gene1621 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01622 S100141_01623 S100141_01623 S100141_01623 1500073 1501053 - hypothetical protein gene gene1622 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01623 S100141_01624 S100141_01624 S100141_01624 1501283 1501792 + uncharacterized protein Coiled coil. gene gene1623 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01624 S100141_01625 S100141_01625 S100141_01625 1501865 1503454 - Putative uncharacterized symporter Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene1624 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01625 S100141_01626 S100141_01626 S100141_01626 1503613 1504419 - Cell wall-binding protein YocH Cell wall%3B Repeat%3B Secreted%3B Signal%3B Contains 2 LysM repeats%3B KEGG: gwc:GWCH70_1211 peptidoglycan endopeptidase LytE%3B Acting on peptide bonds (peptidases) gene gene1625 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01626 S100141_01627 S100141_01627 recQ recQ 1504655 1506460 - DNA helicase ATP-binding%3B Cytoplasm%3B DNA damage%3B DNA recombination%3B DNA repair%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B SOS response%3B Probable DNA helicase. Required for DNA repair and intramolecular recombinatio%3B probably has overlapping function with RecS (AC P50729). It probably acts to help generate ss-DNA from ds-DNA breaks%3B Belongs to the helicase family. RecQ subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B Contains 1 HRDC domain%3B KEGG: bli:BL01304 ATP-dependent DNA helicase RecQ gene gene1626 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01627 S100141_01628 S100141_01628 S100141_01628 1506599 1507117 - uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1627 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01628 S100141_01629 S100141_01629 S100141_01629 1507193 1507354 + hypothetical protein gene gene1628 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01629 S100141_01630 S100141_01630 S100141_01630 1507594 1507770 + uncharacterized protein Coiled coil. gene gene1629 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01630 S100141_01631 S100141_01631 S100141_01631 1507896 1507969 + tRNA-Arg tRNA gene1630 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01631 S100141_01632 S100141_01632 S100141_01632 1508153 1508506 - uncharacterized protein gene gene1631 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01632 S100141_01633 S100141_01633 S100141_01633 1509412 1510377 - hypothetical protein gene gene1632 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01633 S100141_01634 S100141_01634 S100141_01634 1510687 1511247 - uncharacterized protein gene gene1633 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01634 S100141_01635 S100141_01635 fdoG fdoG 1511240 1514383 - Formate dehydrogenase 2Fe-2S%3B 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Molybdenum%3B Oxidoreductase%3B Repeat%3B In the C-terminal sectio%3B belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 2Fe-2S ferredoxin-type domain%3B Contains 2 4Fe-4S ferredoxin-type domains%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: bld:BLi02222 formate dehydrogenase major subunit gene gene1634 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01635 S100141_01636 S100141_01636 S100141_01636 1514719 1515375 - hypothetical protein gene gene1635 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01636 S100141_01637 S100141_01637 S100141_01637 1515372 1517036 - Ribonuclease YxiD Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene1636 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01637 S100141_01638 S100141_01638 S100141_01638 1517143 1517349 - hypothetical protein gene gene1637 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01638 S100141_01639 S100141_01639 S100141_01639 1517617 1518282 - uncharacterized protein Contains 1 PilZ domain gene gene1638 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01639 S100141_01640 S100141_01640 S100141_01640 1518531 1518713 - hypothetical protein gene gene1639 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01640 S100141_01641 S100141_01641 S100141_01641 1518875 1519000 - hypothetical protein gene gene1640 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01641 S100141_01642 S100141_01642 S100141_01642 1519012 1519290 - uncharacterized protein gene gene1641 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01642 S100141_01643 S100141_01643 S100141_01643 1519298 1519690 - uncharacterized protein gene gene1642 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01643 S100141_01644 S100141_01644 S100141_01644 1520338 1520616 + hypothetical protein gene gene1643 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01644 S100141_01645 S100141_01645 S100141_01645 1521079 1521366 + uncharacterized protein gene gene1644 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01645 S100141_01646 S100141_01646 S100141_01646 1521656 1522858 - Spore germination protein YndF Cell membrane%3B Germination%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B May be involved in spore germination%3B Belongs to the GerABKC lipoprotein family gene gene1645 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01646 S100141_01647 S100141_01647 S100141_01647 1523098 1523565 + uncharacterized protein Signal. gene gene1646 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01647 S100141_01648 S100141_01648 S100141_01648 1523599 1524441 + hypothetical protein gene gene1647 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01648 S100141_01649 S100141_01649 mtaD mtaD 1524628 1525977 - S-methyl-5'-thioadenosine deaminase Hydrolase%3B Metal-binding%3B Zinc%3B Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine%2C whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine%2C S-adenosyl-L-homocysteine and adenosine to a small extent%3B Belongs to the MTA/SAH deaminase family%3B KEGG: mac:MA1276 5-methylthioadenosine/S-adenosylhomocysteine deaminase gene gene1648 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01649 S100141_01650 S100141_01650 S100141_01650 1526250 1526498 - Spore coat protein Sporulation. gene gene1649 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01650 S100141_01651 S100141_01651 S100141_01651 1526734 1526943 - hypothetical protein gene gene1650 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01651 S100141_01652 S100141_01652 S100141_01652 1527149 1527931 - Chloride peroxidase Antibiotic biosynthesis%3B Oxidoreductase%3B Peroxidase%3B May be a chlorinating enzyme involved in 7- chlorotetracycline biosynthesis. Able to brominate as well%3B Belongs to the bacterial non-heme bromo- and chloro- peroxidases family%3B KEGG: bld:BLi02236 non-heme chloroperoxidase gene gene1651 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01652 S100141_01653 S100141_01653 S100141_01653 1528067 1528558 + SPBc2 prophage-derived uncharacterized protein YoqH Signal. gene gene1652 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01653 S100141_01654 S100141_01654 S100141_01654 1528636 1528872 - Spore coat protein Sporulation. gene gene1653 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01654 S100141_01655 S100141_01655 S100141_01655 1529046 1529669 + Homoserine/homoserine lactone efflux protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Conducts the efflux of homoserine and homoserine lactone%3B Belongs to the rht family gene gene1654 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01655 S100141_01656 S100141_01656 S100141_01656 1530429 1530614 + 30S ribosomal protein S14 type Z Metal-binding%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Zinc%3B Binds 16S rRNA%2C required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site%3B Belongs to the ribosomal protein S14P family. Zinc- binding S14P subfamily gene gene1655 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01656 S100141_01657 S100141_01657 mutT mutT 1530697 1531170 - 8-oxo-dGTP diphosphatase KEGG: pod:PODO_15870 8-oxo-dGTP diphosphatase gene gene1656 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01657 S100141_01658 S100141_01658 S100141_01658 1531364 1534030 - Pyruvate%2C water dikinase ATP-binding%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Transferase%3B Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate%3B Belongs to the PEP-utilizing enzyme family%3B KEGG: bli:BL05212 pyruvate%2C water dikinase gene gene1657 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01658 S100141_01659 S100141_01659 S100141_01659 1534303 1534908 + putative HTH-type transcriptional regulator YxbF DNA-binding%3B Repeat%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 2 HTH tetR-type DNA-binding domains gene gene1658 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01659 S100141_01660 S100141_01660 S100141_01660 1535010 1535135 + hypothetical protein gene gene1659 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01660 S100141_01661 S100141_01661 S100141_01661 1535157 1535621 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1660 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01661 S100141_01662 S100141_01662 S100141_01662 1535742 1536257 + uncharacterized protein Metal-binding%3B Belongs to the DinB family gene gene1661 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01662 S100141_01663 S100141_01663 acpD acpD 1536301 1536927 - FMN-dependent NADH-azoreductase Flavoprotein%3B FMN%3B NAD%3B Oxidoreductase%3B Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH%2C but not NADPH%2C as an electron donor for its activity%3B Belongs to the azoreductase type 1 family%3B KEGG: bli:BL01874 FMN-dependent NADH-azoreductase%3B Acting on other nitrogenous compounds as donors gene gene1662 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01663 S100141_01664 S100141_01664 S100141_01664 1537047 1537535 - General stress protein 16O Metal-binding%3B Stress response%3B Zinc%3B Zinc-finger%3B Contains 1 dksA C4-type zinc finger gene gene1663 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01664 S100141_01665 S100141_01665 S100141_01665 1537649 1537993 - uncharacterized protein gene gene1664 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01665 S100141_01666 S100141_01666 S100141_01666 1538394 1538603 - uncharacterized protein gene gene1665 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01666 S100141_01667 S100141_01667 feaB feaB 1538863 1540359 + Phenylacetaldehyde dehydrogenase NAD%3B Oxidoreductase%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: bld:BLi02249 phenylacetaldehyde dehydrogenase gene gene1666 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01667 S100141_01668 S100141_01668 S100141_01668 1540450 1541727 + putative MFS-type transporter YjbB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene1667 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01668 S100141_01669 S100141_01669 S100141_01669 1541913 1542449 - Ribosomal-protein-alanine N-acetyltransferase Acyltransferase%3B Cytoplasm%3B Transferase%3B This enzyme acetylates the N-terminal alanine of ribosomal protein S5%3B Belongs to the acetyltransferase family. RimJ subfamily%3B Contains 1 N-acetyltransferase domain%3B KEGG: bce:BC0964 ribosomal-protein-alanine N-acetyltransferase gene gene1668 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01669 S100141_01670 S100141_01670 S100141_01670 1542467 1542868 - Cytidine deaminase KEGG: psf:PSE_1583 cytidine deaminase gene gene1669 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01670 S100141_01671 S100141_01671 sqhC sqhC 1543139 1545028 + Sporulenol synthase Cell membrane%3B Lyase%3B Membrane%3B Repeat%3B Catalyzes the cyclization of tetraprenyl beta-curcumene into sporulenol%3B Belongs to the terpene cyclase/mutase family%3B Contains 3 PFTB repeats%3B KEGG: bli:BL00583 sporulenol synthase gene gene1670 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01671 S100141_01672 S100141_01672 sod2 sod2 1545025 1545870 + Superoxide dismutase Manganese%3B Metal-binding%3B Oxidoreductase%3B Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems%3B Belongs to the iron/manganese superoxide dismutase family%3B KEGG: bli:BL00582 superoxide dismutase%2C Fe-Mn family gene gene1671 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01672 S100141_01673 S100141_01673 S100141_01673 1546478 1547008 + Stress response protein YvgO Signal%3B Stress response. gene gene1672 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01673 S100141_01674 S100141_01674 S100141_01674 1547233 1548573 - putative sodium-dependent transporter Cell membrane%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Putative sodium-dependent transporter. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2. A. 22) family gene gene1673 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01674 S100141_01675 S100141_01675 S100141_01675 1548788 1549768 + putative sodium-dependent transporter YocS Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the bile acid:sodium symporter (BASS) (TC 2. A. 28) family gene gene1674 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01675 S100141_01676 S100141_01676 dlsT dlsT 1549797 1551077 - Dihydrolipoyllysine-residue succinyltransferase Acyltransferase%3B Lipoyl%3B Transferase%3B Tricarboxylic acid cycle%3B The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1)%2C dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: cvi:CV_1072 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) gene gene1675 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01676 S100141_01677 S100141_01677 ogdH ogdH 1551092 1553926 - Oxoglutarate dehydrogenase (succinyl-transferring) Glycolysis%3B Oxidoreductase%3B Thiamine pyrophosphate%3B The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1)%2C dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)%3B Belongs to the alpha-ketoglutarate dehydrogenase family%3B KEGG: bsu:BSU19370 2-oxoglutarate dehydrogenase E1 component gene gene1676 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01677 S100141_01678 S100141_01678 S100141_01678 1554312 1556225 - uncharacterized protein Signal%3B Contains 1 VWFA domain gene gene1677 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01678 S100141_01679 S100141_01679 S100141_01679 1556235 1557125 - uncharacterized protein ATP-binding%3B Nucleotide-binding%3B Belongs to the CbbQ/NirQ/NorQ/GpvN family gene gene1678 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01679 S100141_01680 S100141_01680 sod1 sod1 1557220 1557813 - Superoxide dismutase Cell membrane%3B Copper%3B Disulfide bond%3B Lipoprotein%3B Membrane%3B Metal-binding%3B Palmitate%3B Signal%3B Zinc%3B Belongs to the Cu-Zn superoxide dismutase family%3B KEGG: bli:BL01449 superoxide dismutase%2C Cu-Zn family gene gene1679 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01680 S100141_01681 S100141_01681 lytF lytF 1557923 1559230 - D-gamma-glutamyl-meso-diaminopimelic acid endopeptidase CwlS Cell wall biogenesis/degradation%3B Hydrolase%3B Protease%3B Repeat%3B Signal%3B Thiol protease%3B Probably functions as a cell separation enzyme in addition to LytE and LytF%3B Belongs to the peptidase C40 family%3B Contains 4 LysM repeats%3B KEGG: bsu:BSU09370 peptidoglycan endopeptidase LytF%3B Acting on peptide bonds (peptidases) gene gene1680 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01681 S100141_01682 S100141_01682 S100141_01682 1560362 1561720 + putative multidrug resistance protein NorM Antiport%3B Cell membrane%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Multidrug efflux pump%3B Belongs to the multi antimicrobial extrusion (MATE) (TC 2. A. 66. 1) family gene gene1681 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01682 S100141_01683 S100141_01683 S100141_01683 1561764 1562429 - putative N-acetyl-alpha-D-glucosaminyl L-malate deacetylase Hydrolase%3B Metal-binding%3B Zinc%3B Involved in bacillithiol (BSH) biosynthesis. Catalyzes the second step of the pathway%2C the deacetylation of N- acetylglucosaminylmalate (GlcNAc-Mal) to glucosamine malate (GlcN- Mal). Has weak activity compared with bshB1%3B Belongs to the PIGL family gene gene1682 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01683 S100141_01684 S100141_01684 S100141_01684 1562447 1562797 - uncharacterized protein gene gene1683 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01684 S100141_01685 S100141_01685 S100141_01685 1562799 1563074 - uncharacterized protein gene gene1684 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01685 S100141_01686 S100141_01686 S100141_01686 1563149 1564081 - putative transporter YojE Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene1685 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01686 S100141_01687 S100141_01687 S100141_01687 1564164 1564616 + Spore germination protein GerT Germination%3B Involved in spore germination gene gene1686 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01687 S100141_01688 S100141_01688 S100141_01688 1564569 1564664 - hypothetical protein gene gene1687 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01688 S100141_01689 S100141_01689 S100141_01689 1564845 1565543 + Cellulase Cell wall%3B Secreted%3B Signal%3B May promote colonization of plant roots. May cause loosening and extension of plant cell walls by disrupting non- covalent bonding between cellulose microfibrils and matrix glucans. Has very low expansin activity (in vitro). No enzymatic activity has been found. Binds to peptidoglycan and to plant cell walls%3B Contains 1 expansin-like EG45 domain%3B KEGG: cmi:pCM1_0020 endoglucanase gene gene1688 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01689 S100141_01690 S100141_01690 S100141_01690 1565655 1565933 - uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1689 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01690 S100141_01691 S100141_01691 S100141_01691 1565999 1566745 - 3-oxoacyl-(acyl-carrier-protein) reductase FabG Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B NADP%3B Oxidoreductase%3B Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products%2C the first reductive step in the elongation cycle of fatty acid biosynthesis%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bli:BL01442 null%3B Oxidoreductases gene gene1690 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01691 S100141_01692 S100141_01692 S100141_01692 1566751 1567071 - HTH-type transcriptional regulator YodB Activator%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Negatively regulates yodC and azoR1 which may contribute to the degradation of aromatic compounds. Probably positively regulates the catechol-specific transcription of mhqNOP%2C mhqED%2C and mhqA%3B Contains 1 HTH hxlR-type DNA-binding domain gene gene1691 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01692 S100141_01693 S100141_01693 S100141_01693 1567206 1567826 + Putative NAD(P)H nitroreductase YdgI Flavoprotein%3B FMN%3B NAD%3B NADP%3B Oxidoreductase%3B Belongs to the nitroreductase family%3B KEGG: hap:HAPS_2135 null%3B Oxidoreductases gene gene1692 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01693 S100141_01694 S100141_01694 S100141_01694 1567871 1568476 - Putative hydrolase Aromatic hydrocarbons catabolism%3B Cytoplasm%3B Detoxification%3B Hydrolase%3B Putative hydrolase that may contribute to the degradation of aromatic compounds%3B Belongs to the AB hydrolase superfamily. AB hydrolase 2 family gene gene1693 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01694 S100141_01695 S100141_01695 S100141_01695 1568841 1569044 + putative membrane protein YoyD Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1694 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01695 S100141_01696 S100141_01696 S100141_01696 1569044 1570525 + putative symporter YodF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene1695 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01696 S100141_01697 S100141_01697 S100141_01697 1570589 1571449 - putative transposase-like protein DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene1696 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01697 S100141_01698 S100141_01698 S100141_01698 1571419 1571751 - hypothetical protein gene gene1697 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01698 S100141_01699 S100141_01699 ctpA ctpA 1571858 1573255 - C-terminal processing peptidase Hydrolase%3B Protease%3B Serine protease%3B Signal%3B Belongs to the peptidase S41A family%3B Contains 1 PDZ (DHR) domain%3B KEGG: bli:BL01439 carboxyl-terminal processing protease gene gene1698 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01699 S100141_01700 S100141_01700 S100141_01700 1573415 1574125 + putative methyltransferase YodH Methyltransferase%3B Transferase%3B Belongs to the methyltransferase superfamily gene gene1699 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01700 S100141_01701 S100141_01701 S100141_01701 1574220 1574474 + uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1700 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01701 S100141_01702 S100141_01702 vanY vanY 1574510 1575331 - Serine-type D-Ala-D-Ala carboxypeptidase Carboxypeptidase%3B Cell membrane%3B Hydrolase%3B Lipoprotein%3B Membrane%3B Palmitate%3B Protease%3B Signal%3B Belongs to the peptidase M15B family%3B KEGG: bli:BL01438 D-alanyl-D-alanine carboxypeptidase gene gene1701 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01702 S100141_01703 S100141_01703 deoD deoD 1575365 1576063 - Purine-nucleoside phosphorylase Glycosyltransferase%3B Transferase%3B Belongs to the PNP/UDP phosphorylase family%3B KEGG: shp:Sput200_1676 purine-nucleoside phosphorylase gene gene1702 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01703 S100141_01704 S100141_01704 S100141_01704 1576273 1577280 + UPF0718 protein YcgR Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0718 family gene gene1703 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01704 S100141_01705 S100141_01705 S100141_01705 1577297 1578169 + hypothetical protein gene gene1704 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01705 S100141_01706 S100141_01706 S100141_01706 1578237 1578371 + uncharacterized protein gene gene1705 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01706 S100141_01707 S100141_01707 S100141_01707 1578409 1578729 - uncharacterized protein gene gene1706 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01707 S100141_01708 S100141_01708 bcrC bcrC 1578784 1579503 - Undecaprenyl-diphosphate phosphatase Cell membrane%3B Hydrolase%3B Membrane%3B Signal%3B Transmembrane%3B Transmembrane helix%3B Belongs to the PA-phosphatase related phosphoesterase family%3B KEGG: lsa:LSA1438 undecaprenyl-diphosphatase gene gene1707 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01708 S100141_01709 S100141_01709 S100141_01709 1579506 1579676 - uncharacterized protein gene gene1708 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01709 S100141_01710 S100141_01710 S100141_01710 1579799 1579933 + putative membrane protein YoyF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1709 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01710 S100141_01711 S100141_01711 S100141_01711 1579926 1580606 - uncharacterized protein gene gene1710 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01711 S100141_01712 S100141_01712 S100141_01712 1580769 1580990 - UPF0346 protein Belongs to the UPF0346 family gene gene1711 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01712 S100141_01713 S100141_01713 S100141_01713 1581096 1581377 - uncharacterized protein gene gene1712 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01713 S100141_01714 S100141_01714 kamA kamA 1581374 1582783 - Lysine 2%2C3-aminomutase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Isomerase%3B Metal-binding%3B Pyridoxal phosphate%3B S-adenosyl-L-methionine%3B Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine%3B Belongs to the radical SAM superfamily. KamA family%3B KEGG: bli:BL01430 lysine 2%2C3-aminomutase gene gene1713 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01714 S100141_01715 S100141_01715 S100141_01715 1582882 1583715 - Lysine 2%2C3-aminomutase Acyltransferase%3B Transferase%3B In vitro%2C is able to catalyze the acetylation of beta- lysine to N6-acetyl-beta-lysine%2C an archaeal osmolyte produced by methanogenic archaea. Its physiological function has not yet been elucidated%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: det:DET0221 lysine 2%2C3-aminomutase gene gene1714 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01715 S100141_01716 S100141_01716 argE argE 1583744 1585012 - Acetylornithine deacetylase Cobalt%3B Hydrolase%3B Metal-binding%3B Zinc%3B Belongs to the peptidase M20A family%3B KEGG: bsu:BSU19710 acetylornithine deacetylase gene gene1715 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01716 S100141_01717 S100141_01717 scoB scoB 1585026 1585679 - 3-oxoacid CoA-transferase Transferase%3B Belongs to the 3-oxoacid CoA-transferase subunit B family%3B KEGG: samy:DB32_004337 3-oxoacid CoA-transferase subunit B gene gene1716 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01717 S100141_01718 S100141_01718 atoD atoD 1585661 1586353 - Acetate CoA-transferase Transferase%3B Belongs to the 3-oxoacid CoA-transferase subunit A family%3B KEGG: bli:BL01426 acetate CoA/acetoacetate CoA-transferase alpha subunit gene gene1717 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01718 S100141_01719 S100141_01719 bioA bioA 1586350 1587690 - Adenosylmethionine--8-amino-7-oxononanoate transaminase Aminotransferase%3B Pyridoxal phosphate%3B Transferase%3B Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: rma:Rmag_0118 adenosylmethionine---8-amino-7-oxononanoate aminotransferase gene gene1718 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01719 S100141_01720 S100141_01720 S100141_01720 1587857 1589092 - hypothetical protein gene gene1719 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01720 S100141_01721 S100141_01721 S100141_01721 1589441 1590211 - putative N-acetyltransferase CgeE Acyltransferase%3B Transferase%3B May be involved in maturation of the outermost layer of the spore. Contains 1 N-acetyltransferase domain gene gene1720 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01721 S100141_01722 S100141_01722 msrB msrB 1590329 1590784 - Peptide-methionine (R)-S-oxide reductase Oxidoreductase%3B Belongs to the MsrB Met sulfoxide reductase family%3B KEGG: bst:GYO_2391 peptide-methionine (R)-S-oxide reductase gene gene1721 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01722 S100141_01723 S100141_01723 msrA msrA 1590771 1591316 - Peptide-methionine (S)-S-oxide reductase Oxidoreductase%3B Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine%3B Belongs to the MsrA Met sulfoxide reductase family%3B KEGG: bsu:BSU21690 peptide-methionine (S)-S-oxide reductase gene gene1722 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01723 S100141_01724 S100141_01724 S100141_01724 1591691 1592125 + putative HTH-type transcriptional regulator YpoP DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH marR-type DNA-binding domain gene gene1723 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01724 S100141_01725 S100141_01725 S100141_01725 1592191 1592442 + hypothetical protein gene gene1724 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01725 S100141_01726 S100141_01726 dge1 dge1 1592503 1593591 - Diguanylate cyclase Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Contains 1 EAL domain%3B Contains 1 GGDEF domain%3B Contains 1 MHYT domain%3B KEGG: bli:BL05221 diguanylate cyclase gene gene1725 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01726 S100141_01727 S100141_01727 S100141_01727 1593725 1595056 - putative multidrug resistance protein YpnP Antiport%3B Cell membrane%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the multi antimicrobial extrusion (MATE) (TC 2. A. 66. 1) family gene gene1726 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01727 S100141_01728 S100141_01728 S100141_01728 1595152 1595856 + hypothetical protein gene gene1727 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01728 S100141_01729 S100141_01729 S100141_01729 1595953 1596153 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1728 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01729 S100141_01730 S100141_01730 S100141_01730 1596185 1596757 - uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1729 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01730 S100141_01731 S100141_01731 S100141_01731 1596768 1597520 - uncharacterized protein gene gene1730 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01731 S100141_01732 S100141_01732 S100141_01732 1597663 1598265 - SCO1 protein like protein Cell membrane%3B Chaperone%3B Copper%3B Lipoprotein%3B Membrane%3B Metal-binding%3B Palmitate%3B Signal%3B Neccessary for insertion of copper into the active site of cytochrome c oxidase. May play a role in copper homeostasis or redox signaling%3B Belongs to the SCO1/2 family%3B Contains 1 thioredoxin domain gene gene1731 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01732 S100141_01733 S100141_01733 S100141_01733 1598262 1599104 - DegV domain-containing protein Lipid-binding%3B May bind long-chain fatty acids%2C such as palmitate%2C and may play a role in lipid transport or fatty acid metabolism%3B Contains 1 DegV domain gene gene1732 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01733 S100141_01734 S100141_01734 S100141_01734 1599252 1599503 - uncharacterized protein gene gene1733 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01734 S100141_01735 S100141_01735 ilvA ilvA 1599596 1600864 - Threonine ammonia-lyase Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Isoleucine biosynthesis%3B Lyase%3B Pyridoxal phosphate%3B Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate)%2C which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell%2C the second step is accelerated by RidA (By similarity)%3B Belongs to the serine/threonine dehydratase family%3B Contains 1 ACT-like domain%3B KEGG: bsu:BSU21770 threonine dehydratase gene gene1734 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01735 S100141_01736 S100141_01736 S100141_01736 1601098 1602099 + Psp operon transcriptional activator Activator%3B ATP-binding%3B Cytoplasm%3B DNA-binding%3B Nucleotide-binding%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Transcriptional activator for the phage shock protein (psp) operon (pspABCDE) and pspG gene%3B Contains 1 sigma-54 factor interaction domain gene gene1735 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01736 S100141_01737 S100141_01737 S100141_01737 1602115 1602756 + Hemolysin-3 like protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0073 (Hly-III) family gene gene1736 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01737 S100141_01738 S100141_01738 S100141_01738 1602797 1603420 - 1-acylglycerol-3-phosphate O-acyltransferase KEGG: bss:BSUW23_10665 1-acyl-sn-glycerol-3-phosphate acyltransferase gene gene1737 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01738 S100141_01739 S100141_01739 S100141_01739 1603435 1603923 - Dihydrofolate reductase Antibiotic resistance%3B Methotrexate resistance%3B NADP%3B One-carbon metabolism%3B Oxidoreductase%3B Plasmid%3B Trimethoprim resistance%3B Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis%2C and for DNA precursor synthesis (By similarity)%3B Belongs to the dihydrofolate reductase family%3B Contains 1 DHFR (dihydrofolate reductase) domain%3B KEGG: eco:b0048 dihydrofolate reductase gene gene1738 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01739 S100141_01740 S100141_01740 S100141_01740 1604279 1604827 - Phosphatidylglycerophosphatase To B. subtilis YutG%3B KEGG: bpu:BPUM_1917 phosphatidylglycerophosphatase A gene gene1739 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01740 S100141_01741 S100141_01741 S100141_01741 1604843 1605445 - uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1740 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01741 S100141_01742 S100141_01742 S100141_01742 1605717 1606487 - uncharacterized protein gene gene1741 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01742 S100141_01743 S100141_01743 S100141_01743 1606524 1606958 - UPF0403 protein Belongs to the UPF0403 family gene gene1742 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01743 S100141_01744 S100141_01744 ilvD ilvD 1607050 1608726 - Dihydroxy-acid dehydratase 4Fe-4S%3B Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Iron%3B Iron-sulfur%3B Lyase%3B Metal-binding%3B Belongs to the IlvD/Edd family%3B KEGG: bli:BL05225 dihydroxy-acid dehydratase gene gene1743 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01744 S100141_01745 S100141_01745 S100141_01745 1609056 1610192 - uncharacterized protein gene gene1744 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01745 S100141_01746 S100141_01746 S100141_01746 1610223 1610894 - uncharacterized protein Contains 1 HD domain gene gene1745 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01746 S100141_01747 S100141_01747 S100141_01747 1610882 1611361 - Glutathione peroxidase Abscisic acid signaling pathway%3B Mitochondrion%3B Oxidoreductase%3B Peroxidase%3B Stress response%3B Transit peptide%3B May constitute a glutathione peroxidase-like protective system against oxidative stresses. Involved positively in abscisic acid (ABA) signaling pathway that regulates numerous ABA responses%2C such as stomatal closure%2C seed germination and inhibition of vegetative growth. Oxidizes and represses target proteins (e. g. the phosphatase activity of ABI1 and ABI2) when oxidized by H(2)O(2)%2C probably after ABA signaling. Modulates the calcium channel activity in guard cells in response to ABA or H(2)O(2). Confers tolerance to drought stress%2C by enhancing the ABA-dependent stomatal closure%3B Belongs to the glutathione peroxidase family%3B KEGG: slo:Shew_2741 glutathione peroxidase gene gene1746 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01747 S100141_01748 S100141_01748 S100141_01748 1611377 1613056 - Formate--tetrahydrofolate ligase ATP-binding%3B Ligase%3B Nucleotide-binding%3B One-carbon metabolism%3B Belongs to the formate--tetrahydrofolate ligase family%3B KEGG: bli:BL01370 formate--tetrahydrofolate ligase gene gene1747 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01748 S100141_01749 S100141_01749 metA metA 1613208 1614116 + Homoserine O-succinyltransferase Acyltransferase%3B Amino-acid biosynthesis%3B Cytoplasm%3B Methionine biosynthesis%3B Transferase%3B Belongs to the HTS family%3B KEGG: bli:BL01365 homoserine O-succinyltransferase gene gene1748 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01749 S100141_01750 S100141_01750 ugtP ugtP 1614387 1615538 + 1%2C2-diacylglycerol 3-glucosyltransferase Carbohydrate metabolism%3B Cell membrane%3B Glycosyltransferase%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Transferase%3B Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG)%2C thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1%2C2-diacyl- sn-glycerol)%2C beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1->6)-D-glucopyranosyl)-1%2C2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D- glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1%2C2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)%3B Belongs to the glycosyltransferase 28 family. UgtP subfamily%3B KEGG: bsu:BSU21920 processive 1%2C2-diacylglycerol beta-glucosyltransferase gene gene1749 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01750 S100141_01751 S100141_01751 S100141_01751 1615588 1616277 - hypothetical protein gene gene1750 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01751 S100141_01752 S100141_01752 S100141_01752 1616552 1616752 + Cold shock protein CspB Activator%3B Cytoplasm%3B DNA-binding%3B Stress response%3B Transcription%3B Transcription regulation%3B Binds to the pentamer sequences ATTGG and CCAAT with highest affinity in single-stranded DNA%2C and also to other sequences. Has greater affinity for ATTGG than CCAAT. Can act as transcriptional activator of cold shock genes by recognizing putative ATTGG-box elements present in promoter regions of genes induced under cold shock conditions%3B Contains 1 CSD (cold-shock) domain gene gene1751 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01752 S100141_01753 S100141_01753 S100141_01753 1616808 1616990 - Regulatory protein DegR Transcription%3B Transcription regulation%3B Stabilizes the phosphorylated form of DegU%2C leading to enhanced production of levansucrase%2C alkaline protease%2C and neutral protease gene gene1752 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01753 S100141_01754 S100141_01754 S100141_01754 1617149 1617415 + uncharacterized protein gene gene1753 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01754 S100141_01755 S100141_01755 S100141_01755 1617499 1617684 - uncharacterized protein gene gene1754 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01755 S100141_01756 S100141_01756 rnhA rnhA 1617699 1618358 - Ribonuclease H Contains 1 RNase H domain%3B KEGG: blh:BaLi_c24240 ribonuclease HI gene gene1755 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01756 S100141_01757 S100141_01757 S100141_01757 1618434 1619135 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1756 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01757 S100141_01758 S100141_01758 S100141_01758 1619125 1619523 + Ribonuclease H Metal-binding%3B Not know%3B does not have RNase H activity. Belongs to the RNase H family. EbsB subfamily%3B Contains 1 RNase H domain%3B KEGG: bli:BL00670 ribonuclease HI gene gene1757 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01758 S100141_01759 S100141_01759 S100141_01759 1619566 1619712 + hypothetical protein gene gene1758 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01759 S100141_01760 S100141_01760 S100141_01760 1619926 1620813 - DNA-directed DNA polymerase DNA-binding%3B Exonuclease%3B Hydrolase%3B Nuclease%3B 5'-3' exonuclease acting preferentially on double- stranded DNA%3B Contains 1 5'-3' exonuclease domain%3B KEGG: lpl:lp_1508 DNA polymerase I gene gene1759 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01760 S100141_01761 S100141_01761 S100141_01761 1620898 1621047 - uncharacterized protein gene gene1760 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01761 S100141_01762 S100141_01762 S100141_01762 1621127 1621396 - uncharacterized protein gene gene1761 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01762 S100141_01763 S100141_01763 S100141_01763 1621471 1625034 - uncharacterized protein ATP-binding%3B Nucleotide-binding. gene gene1762 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01763 S100141_01764 S100141_01764 S100141_01764 1625337 1625840 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1763 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01764 S100141_01765 S100141_01765 S100141_01765 1625848 1626945 - Putative chalcone synthase Acyltransferase%3B Transferase%3B Belongs to the chalcone/stilbene synthases family gene gene1764 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01765 S100141_01766 S100141_01766 S100141_01766 1626987 1627538 - Phosphinothricin acetyltransferase KEGG: mve:X875_15470 phosphinothricin acetyltransferase gene gene1765 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01766 S100141_01767 S100141_01767 S100141_01767 1627623 1628939 - Xanthine permease Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Transport of xanthine in the cell. Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2. A. 40) subfamily gene gene1766 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01767 S100141_01768 S100141_01768 S100141_01768 1628936 1629520 - Xanthine phosphoribosyltransferase Cytoplasm%3B Glycosyltransferase%3B Purine salvage%3B Transferase%3B Converts the preformed base xanthine%2C a product of nucleic acid breakdown%2C to xanthosine 5'-monophosphate (XMP)%2C so it can be reused for RNA or DNA synthesis%3B Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily%3B KEGG: bli:BL00680 xanthine phosphoribosyltransferase gene gene1767 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01768 S100141_01769 S100141_01769 S100141_01769 1629876 1631378 - Carboxypeptidase Taq Carboxypeptidase%3B Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Zinc%3B Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus%2C including neutral%2C aromatic%2C polar and basic residues. Has lower activity with substrates ending with His or Trp%3B Belongs to the peptidase M32 family%3B KEGG: bli:BL00681 carboxypeptidase Taq gene gene1768 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01769 S100141_01770 S100141_01770 dinG dinG 1631492 1633411 - DNA helicase ATP-binding%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Belongs to the helicase family. DinG subfamily%3B Contains 1 helicase ATP-binding domain%3B KEGG: bli:BL05232 ATP-dependent DNA helicase DinG gene gene1769 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01770 S100141_01771 S100141_01771 S100141_01771 1633520 1633696 - hypothetical protein gene gene1770 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01771 S100141_01772 S100141_01772 S100141_01772 1633974 1634384 + hypothetical protein gene gene1771 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01772 S100141_01773 S100141_01773 ypsC ypsC 1634512 1635663 - Putative RNA methyltransferase YpsC Methyltransferase%3B Transferase%3B Belongs to the methyltransferase superfamily%3B Contains 1 THUMP domain%3B KEGG: bli:BL05234 putative N6-adenine-specific DNA methylase%3B Methyltransferases gene gene1772 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01773 S100141_01774 S100141_01774 S100141_01774 1636198 1636494 - Cell cycle protein GpsB Cell cycle%3B Cell division%3B Cell shape%3B Coiled coil%3B Cytoplasm%3B Divisome component that associates with the complex late in its assembly%2C after the Z-ring is formed%2C and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA%2C is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation%3B Belongs to the GpsB family gene gene1773 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01774 S100141_01775 S100141_01775 S100141_01775 1636575 1637126 - UPF0398 protein Belongs to the UPF0398 family gene gene1774 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01775 S100141_01776 S100141_01776 S100141_01776 1637242 1637511 - Spore coat protein Sporulation. gene gene1775 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01776 S100141_01777 S100141_01777 S100141_01777 1637596 1637691 - hypothetical protein gene gene1776 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01777 S100141_01778 S100141_01778 S100141_01778 1637753 1639066 - uncharacterized protein gene gene1777 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01778 S100141_01779 S100141_01779 S100141_01779 1639072 1641348 - DEAD-box ATP-dependent RNA helicase ATP-binding%3B Coiled coil%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B RNA-binding%3B Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain gene gene1778 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01779 S100141_01780 S100141_01780 S100141_01780 1641449 1641955 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cytoplasm%3B Kinase%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane%3B Contains 1 PTS EIIA type-1 domain%3B KEGG: bsu:BSU22230 PTS system%2C glucose-specific IIA component gene gene1779 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01780 S100141_01781 S100141_01781 S100141_01781 1642131 1642550 + uncharacterized protein Signal. gene gene1780 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01781 S100141_01782 S100141_01782 S100141_01782 1642569 1643012 - uncharacterized protein gene gene1781 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01782 S100141_01783 S100141_01783 S100141_01783 1643183 1643392 + uncharacterized protein gene gene1782 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01783 S100141_01784 S100141_01784 S100141_01784 1643425 1643796 - uncharacterized protein gene gene1783 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01784 S100141_01785 S100141_01785 S100141_01785 1643854 1644081 - hypothetical protein gene gene1784 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01785 S100141_01786 S100141_01786 S100141_01786 1644281 1644385 + hypothetical protein gene gene1785 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01786 S100141_01787 S100141_01787 S100141_01787 1644418 1645377 - uncharacterized protein gene gene1786 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01787 S100141_01788 S100141_01788 S100141_01788 1645431 1646027 + Holliday junction resolvase RecU Cytoplasm%3B DNA damage%3B DNA recombination%3B DNA repair%3B Endonuclease%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nuclease%3B Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands%3B Belongs to the RecU family gene gene1787 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01788 S100141_01789 S100141_01789 mrcA mrcA 1646085 1648772 + Penicillin-binding protein 1A/1B Antibiotic resistance%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Glycosyltransferase%3B Hydrolase%3B Membrane%3B Multifunctional enzyme%3B Peptidoglycan synthesis%3B Signal-anchor%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) (By similarity)%3B In the N-terminal sectio%3B belongs to the glycosyltransferase 51 family%3B In the C-terminal sectio%3B belongs to the transpeptidase family%3B Contains 1 fibronectin type-III domain%3B KEGG: bli:BL02732 penicillin-binding protein 1A%3B Hexosyltransferases gene gene1788 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01789 S100141_01790 S100141_01790 S100141_01790 1648793 1649296 - uncharacterized protein Phosphoprotein. gene gene1789 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01790 S100141_01791 S100141_01791 S100141_01791 1649293 1649955 - DNA-(apurinic or apyrimidinic site) lyase 4Fe-4S%3B DNA damage%3B DNA repair%3B DNA-binding%3B Glycosidase%3B Hydrolase%3B Iron%3B Iron-sulfur%3B Lyase%3B Metal-binding%3B DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond%2C leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination%2C leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate%3B Belongs to the Nth/MutY family%3B Contains 1 HhH domain%3B KEGG: nsa:Nitsa_1368 endonuclease III gene gene1790 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01791 S100141_01792 S100141_01792 S100141_01792 1649972 1650670 - DNA replication protein DnaD DNA replication%3B Primosome. gene gene1791 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01792 S100141_01793 S100141_01793 narS narS 1650745 1652037 - Asparagine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: bsu:BSU22360 asparaginyl-tRNA synthetase gene gene1792 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01793 S100141_01794 S100141_01794 aspB aspB 1652187 1653371 - Aspartate transaminase Aminotransferase%3B Cytoplasm%3B Pyridoxal phosphate%3B Transferase%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: woo:wOo_04400 aspartate aminotransferase gene gene1793 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01794 S100141_01795 S100141_01795 S100141_01795 1653393 1653878 - uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1794 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01795 S100141_01796 S100141_01796 S100141_01796 1653888 1654058 - uncharacterized protein gene gene1795 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01796 S100141_01797 S100141_01797 S100141_01797 1654211 1657003 - DNA helicase ATP-binding%3B DNA damage%3B DNA recombination%3B DNA repair%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Probable helicase involved in DNA repair and perhaps also replication%3B Belongs to the helicase family. DinG subfamily%3B Contains 1 exonuclease domain%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bli:BL02749 ATP-dependent DNA helicase DinG gene gene1796 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01797 S100141_01798 S100141_01798 panD panD 1657141 1657524 - Aspartate 1-decarboxylase Autocatalytic cleavage%3B Cytoplasm%3B Decarboxylase%3B Lyase%3B Pantothenate biosynthesis%3B Pyruvate%3B Schiff base%3B Zymogen%3B Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine%3B Belongs to the PanD family%3B KEGG: bli:BL02750 aspartate 1-decarboxylase gene gene1797 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01798 S100141_01799 S100141_01799 panC panC 1657524 1658390 - Pantoate--beta-alanine ligase (AMP-forming) ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Pantothenate biosynthesis%3B Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate%3B Belongs to the pantothenate synthetase family%3B KEGG: bli:BL02751 pantoate--beta-alanine ligase gene gene1798 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01799 S100141_01800 S100141_01800 panB panB 1658393 1659226 - 3-methyl-2-oxobutanoate hydroxymethyltransferase Cytoplasm%3B Magnesium%3B Metal-binding%3B Pantothenate biosynthesis%3B Transferase%3B Catalyzes the reversible reaction in which hydroxymethyl group from 5%2C10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate%3B Belongs to the PanB family%3B KEGG: bli:BL02752 3-methyl-2-oxobutanoate hydroxymethyltransferase gene gene1799 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01800 S100141_01801 S100141_01801 birA birA 1659476 1660459 - Biotin--[acetyl-CoA-carboxylase] ligase ATP-binding%3B Biotin%3B DNA-binding%3B Ligase%3B Nucleotide-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor%3B Belongs to the biotin--protein ligase family%3B Contains 1 BPL/LPL catalytic domain%3B KEGG: bli:BL02753 BirA family transcriptional regulator%2C biotin operon repressor / biotin-(acetyl-CoA-carboxylase) ligase gene gene1800 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01801 S100141_01802 S100141_01802 S100141_01802 1660444 1661637 - CCA-adding enzyme ATP-binding%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Nucleotidyltransferase%3B RNA repair%3B RNA-binding%3B Transferase%3B tRNA processing%3B Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C%2C C%2C and A to the tRNA nucleotide-73%2C using CTP and ATP as substrates and producing inorganic pyrophosphate%3B Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily%3B KEGG: bss:BSUW23_11010 tRNA nucleotidyltransferase (CCA-adding enzyme)%3B CCA tRNA nucleotidyltransferase gene gene1801 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01802 S100141_01803 S100141_01803 S100141_01803 1661597 1662778 - N-acetyl-alpha-D-glucosaminyl L-malate synthase Glycosyltransferase%3B Nucleotide-binding%3B Transferase%3B Involved in bacillithiol (BSH) biosynthesis. Catalyzes the first step of the pathway%2C the formation of N- acetylglucosaminylmalate (GlcNAc-Mal) from UDP-N-acetylglucosamine (UDP-GlcNAc) and L-malate%3B Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: saa:SAUSA300_1349 null%3B Hexosyltransferases gene gene1802 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01803 S100141_01804 S100141_01804 S100141_01804 1662778 1663515 - N-acetyl-alpha-D-glucosaminyl L-malate deacetylase Hydrolase%3B Metal-binding%3B Zinc%3B Involved in bacillithiol (BSH) biosynthesis. Catalyzes the second step of the pathway%2C the deacetylation of N- acetylglucosaminylmalate (GlcNAc-Mal) to glucosamine malate (GlcN- Mal)%3B Belongs to the PIGL family gene gene1803 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01804 S100141_01805 S100141_01805 mgsA mgsA 1663472 1663885 - Methylglyoxal synthase Lyase%3B Belongs to the methylglyoxal synthase family%3B KEGG: amc:MADE_1002670 methylglyoxal synthase gene gene1804 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01805 S100141_01806 S100141_01806 dapB dapB 1663905 1664708 - 4-hydroxy-tetrahydrodipicolinate reductase Amino-acid biosynthesis%3B Cytoplasm%3B Diaminopimelate biosynthesis%3B Lysine biosynthesis%3B NAD%3B NADP%3B Oxidoreductase%3B Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate%3B Belongs to the DapB family%3B KEGG: bli:BL02758 4-hydroxy-tetrahydrodipicolinate reductase gene gene1805 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01806 S100141_01807 S100141_01807 aroA aroA 1664721 1665059 - 3-phosphoshikimate 1-carboxyvinyltransferase KEGG: eao:BD94_0226 3-phosphoshikimate 1-carboxyvinyltransferase gene gene1806 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01807 S100141_01808 S100141_01808 S100141_01808 1665197 1666069 + UPF0750 membrane protein YpjC Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0750 family gene gene1807 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01808 S100141_01809 S100141_01809 S100141_01809 1666112 1666912 - uncharacterized protein Membrane%3B Signal%3B Transmembrane%3B Transmembrane helix. gene gene1808 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01809 S100141_01810 S100141_01810 S100141_01810 1666987 1667571 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1809 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01810 S100141_01811 S100141_01811 S100141_01811 1667809 1668576 - Menaquinol-cytochrome c reductase cytochrome b/c subunit Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Component of the menaquinol-cytochrome c reductase complex. Belongs to the cytochrome b family%3B Contains 1 cytochrome c domain gene gene1810 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01811 S100141_01812 S100141_01812 S100141_01812 1668609 1669283 - Menaquinol-cytochrome c reductase cytochrome b subunit Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Component of the menaquinol-cytochrome c reductase complex. Belongs to the cytochrome b family gene gene1811 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01812 S100141_01813 S100141_01813 qcrA qcrA 1669286 1669792 - Menaquinol-cytochrome c reductase iron-sulfur subunit 2Fe-2S%3B Disulfide bond%3B Electron transport%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase%3B Transport%3B Component of the menaquinol-cytochrome c reductase complex. The Rieske protein is a high potential 2Fe-2S protein. Contains 1 Rieske domain%3B KEGG: bli:BL02762 menaquinol-cytochrome c reductase iron-sulfur subunit%3B With a cytochrome as acceptor gene gene1812 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01813 S100141_01814 S100141_01814 S100141_01814 1669939 1670385 - uncharacterized protein gene gene1813 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01814 S100141_01815 S100141_01815 S100141_01815 1670467 1671006 - UPF0302 protein Belongs to the UPF0302 family gene gene1814 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01815 S100141_01816 S100141_01816 S100141_01816 1671075 1672349 - TPR repeat-containing protein YpiA Repeat%3B TPR repeat%3B Contains 9 TPR repeats gene gene1815 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01816 S100141_01817 S100141_01817 S100141_01817 1672583 1673869 - 3-phosphoshikimate 1-carboxyvinyltransferase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Cytoplasm%3B Transferase%3B Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate%3B Belongs to the EPSP synthase family%3B KEGG: bli:BL02766 3-phosphoshikimate 1-carboxyvinyltransferase gene gene1816 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01817 S100141_01818 S100141_01818 S100141_01818 1673880 1674995 - Prephenate dehydrogenase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B NAD%3B Oxidoreductase%3B Tyrosine biosynthesis%3B Contains 1 ACT domain%3B Contains 1 prephenate/arogenate dehydrogenase domain%3B KEGG: bli:BL02768 prephenate dehydrogenase gene gene1817 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01818 S100141_01819 S100141_01819 hisC hisC 1675049 1676134 - Histidinol-phosphate transaminase Amino-acid biosynthesis%3B Aminotransferase%3B Histidine biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily%3B KEGG: bld:BLi02397 histidinol-phosphate aminotransferase gene gene1818 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01819 S100141_01820 S100141_01820 trpA trpA 1676144 1676947 - Tryptophan synthase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Lyase%3B Tryptophan biosynthesis%3B The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate%3B Belongs to the TrpA family%3B KEGG: bli:BL02770 tryptophan synthase alpha chain%3B overlaps another CDS with the same product name gene gene1819 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01820 S100141_01821 S100141_01821 trpB trpB 1676916 1678142 - Tryptophan synthase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Lyase%3B Pyridoxal phosphate%3B Tryptophan biosynthesis%3B The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine%3B Belongs to the TrpB family%3B KEGG: bli:BL02771 tryptophan synthase beta chain%3B overlaps another CDS with the same product name gene gene1820 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01821 S100141_01822 S100141_01822 trpF trpF 1678123 1678779 - Phosphoribosylanthranilate isomerase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Isomerase%3B Tryptophan biosynthesis%3B Belongs to the TrpF family%3B KEGG: bsr:I33_2325 phosphoribosylanthranilate isomerase gene gene1821 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01822 S100141_01823 S100141_01823 trpC trpC 1678779 1679537 - Indole-3-glycerol-phosphate synthase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Decarboxylase%3B Lyase%3B Tryptophan biosynthesis%3B Belongs to the TrpC family%3B KEGG: bli:BL02773 indole-3-glycerol phosphate synthase gene gene1822 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01823 S100141_01824 S100141_01824 trpD trpD 1679530 1680546 - Anthranilate phosphoribosyltransferase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Glycosyltransferase%3B Magnesium%3B Metal-binding%3B Transferase%3B Tryptophan biosynthesis%3B Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)%3B Belongs to the anthranilate phosphoribosyltransferase family%3B KEGG: bli:BL02774 anthranilate phosphoribosyltransferase gene gene1823 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01824 S100141_01825 S100141_01825 trpE trpE 1680518 1682065 - Anthranilate synthase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Lyase%3B Magnesium%3B Metal-binding%3B Tryptophan biosynthesis%3B Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate%2C an intermediate in the biosynthesis of L-tryptophan. In the first step%2C the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that%2C along with chorismate%2C is used in the second step%2C catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG%2C TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity)%3B Belongs to the anthranilate synthase component I family%3B KEGG: bli:BL02775 anthranilate synthase component I gene gene1824 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01825 S100141_01826 S100141_01826 aroH aroH 1682311 1682694 - Chorismate mutase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Cytoplasm%3B Isomerase%3B Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis%3B Contains 1 chorismate mutase aroH-type domain%3B KEGG: bsu:BSU22690 chorismate mutase gene gene1825 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01826 S100141_01827 S100141_01827 aroB aroB 1682691 1683779 - 3-dehydroquinate synthase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Cobalt%3B Cytoplasm%3B Lyase%3B NAD%3B Zinc%3B Belongs to the dehydroquinate synthase family%3B KEGG: bli:BL02777 3-dehydroquinate synthase gene gene1826 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01827 S100141_01828 S100141_01828 aroC aroC 1683779 1684951 - Chorismate synthase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B FAD%3B Flavoprotein%3B FMN%3B Lyase%3B NADP%3B Catalyzes the anti-1%2C4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate%2C which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system%3B Belongs to the chorismate synthase family%3B KEGG: gsu:GSU2027 chorismate synthase gene gene1827 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01828 S100141_01829 S100141_01829 cheR cheR 1685023 1685790 - Protein-glutamate O-methyltransferase Chemotaxis%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. CheR is responsible for the chemotactic adaptation to repellents. Contains 1 cheR-type methyltransferase domain%3B KEGG: bli:BL02780 chemotaxis protein methyltransferase CheR gene gene1828 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01829 S100141_01830 S100141_01830 S100141_01830 1685930 1686376 - Nucleoside-diphosphate kinase ATP-binding%3B Cytoplasm%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide metabolism%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism%2C using a phosphorylated active-site intermediate%3B Belongs to the NDK family%3B KEGG: eco:b2518 nucleoside-diphosphate kinase gene gene1829 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01830 S100141_01831 S100141_01831 S100141_01831 1686501 1687463 - Heptaprenyl diphosphate synthase Isoprene biosynthesis%3B Magnesium%3B Metal-binding%3B Sporulation%3B Transferase%3B Supplies heptaprenyl diphosphate%2C the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7)%3B Belongs to the FPP/GGPP synthase family%3B KEGG: bli:BL02782 heptaprenyl diphosphate synthase gene gene1830 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01831 S100141_01832 S100141_01832 ubiE ubiE 1687493 1688191 - Demethylmenaquinone methyltransferase Menaquinone biosynthesis%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family%3B KEGG: bsu:BSU22750 demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1%2C4-benzoquinol methylase gene gene1831 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01832 S100141_01833 S100141_01833 S100141_01833 1688194 1688979 - Heptaprenyl diphosphate synthase Isoprene biosynthesis%3B Sporulation%3B Transferase%3B Supplies heptaprenyl diphosphate%2C the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7)%3B KEGG: blh:BaLi_c25000 heptaprenyl diphosphate synthase gene gene1832 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01833 S100141_01834 S100141_01834 S100141_01834 1689113 1689349 - Transcription attenuation protein MtrB RNA-binding%3B Transcription%3B Transcription regulation%3B Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan%3B Belongs to the MtrB family gene gene1833 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01834 S100141_01835 S100141_01835 gch1 gch1 1689371 1689940 - GTP cyclohydrolase I GTP-binding%3B Hydrolase%3B Metal-binding%3B Nucleotide-binding%3B One-carbon metabolism%3B Zinc%3B Belongs to the GTP cyclohydrolase I family%3B KEGG: bsu:BSU22780 GTP cyclohydrolase I gene gene1834 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01835 S100141_01836 S100141_01836 S100141_01836 1690147 1690425 - DNA-binding protein HU-1 DNA condensation%3B DNA-binding%3B Phosphoprotein%3B Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it%2C and thus to prevent its denaturation under extreme environmental conditions%3B Belongs to the bacterial histone-like protein family gene gene1835 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01836 S100141_01837 S100141_01837 S100141_01837 1690843 1692321 - Stage IV sporulation protein ATP-binding%3B Cytoplasm%3B Hydrolase%3B Nucleotide-binding%3B Sporulation%3B ATPase. Has a role at an early stage in the morphogenesis of the spore coat outer layers. Directs the assembly of the coat and exosporium to an area around the forespore gene gene1836 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01837 S100141_01838 S100141_01838 S100141_01838 1692523 1693239 - uncharacterized protein gene gene1837 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01838 S100141_01839 S100141_01839 S100141_01839 1693262 1693465 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1838 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01839 S100141_01840 S100141_01840 gpsA gpsA 1693793 1694833 - Glycerol-3-phosphate dehydrogenase (NAD(P)(+)) Cytoplasm%3B Lipid biosynthesis%3B Lipid metabolism%3B NAD%3B Oxidoreductase%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family%3B KEGG: mmn:midi_00920 glycerol-3-phosphate dehydrogenase (NAD(P)+) gene gene1839 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01840 S100141_01841 S100141_01841 S100141_01841 1694849 1696159 - GTPase Der GTP-binding%3B Nucleotide-binding%3B Repeat%3B Ribosome biogenesis%3B GTPase that plays an essential role in the late steps of ribosome biogenesis%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. EngA (Der) GTPase family%3B Contains 2 EngA-type G (guanine nucleotide-binding) domains%3B Contains 1 KH-like domain gene gene1840 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01841 S100141_01842 S100141_01842 S100141_01842 1696322 1696516 - uncharacterized protein overlaps another CDS with the same product name gene gene1841 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01842 S100141_01843 S100141_01843 S100141_01843 1696513 1697412 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B overlaps another CDS with the same product name gene gene1842 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01843 S100141_01844 S100141_01844 S100141_01844 1697409 1698011 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B overlaps another CDS with the same product name gene gene1843 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01844 S100141_01845 S100141_01845 S100141_01845 1698084 1698215 + uncharacterized protein gene gene1844 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01845 S100141_01846 S100141_01846 S100141_01846 1698245 1699300 - Isopentenyl-diphosphate Delta-isomerase Cytoplasm%3B Flavoprotein%3B FMN%3B Isomerase%3B Isoprene biosynthesis%3B Magnesium%3B Metal-binding%3B NADP%3B Involved in the biosynthesis of isoprenoids. Catalyzes the 1%2C3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer%2C dimethylallyl diphosphate (DMAPP)%3B Belongs to the IPP isomerase type 2 family%3B KEGG: bli:BL02217 isopentenyl-diphosphate delta-isomerase gene gene1845 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01846 S100141_01847 S100141_01847 S100141_01847 1699310 1700458 - 30S ribosomal protein S1 like protein Phosphoprotein%3B Repeat%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B Plays a role in sporulation%3B Belongs to the ribosomal protein S1P family%3B Contains 4 S1 motif domains gene gene1846 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01847 S100141_01848 S100141_01848 S100141_01848 1700676 1701356 - UMP/CMP kinase ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the cytidylate kinase family. Type 1 subfamily%3B KEGG: gxy:GLX_11090 cytidylate kinase gene gene1847 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01848 S100141_01849 S100141_01849 S100141_01849 1701436 1701612 - uncharacterized protein gene gene1848 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01849 S100141_01850 S100141_01850 S100141_01850 1701774 1703126 - Sporulation protein YpeB Germination%3B Sporulation%3B Required for spore cortex hydrolysis during germination. Appears to be required for either expression%2C localization%2C activation or function of SleB. Belongs to the YpeB family gene gene1849 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01850 S100141_01851 S100141_01851 S100141_01851 1703143 1704108 - N-acetylmuramoyl-L-alanine amidase Cell wall biogenesis/degradation%3B Germination%3B Hydrolase%3B Signal%3B Sporulation%3B Required for spore cortex hydrolysis during germination%3B Belongs to the SleB family%3B KEGG: bli:BL02222 N-acetylmuramoyl-L-alanine amidase gene gene1850 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01851 S100141_01852 S100141_01852 S100141_01852 1704247 1704915 - Protease PrsW Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Involved in the degradation of specific anti-sigma factors. Responsible for Site-1 cleavage of the RsiW anti-sigma factor. This results%2C after two other proteolytic steps catalyzed by the RasP and ClpXP proteases%2C in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity)%3B Belongs to the protease PrsW family gene gene1851 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01852 S100141_01853 S100141_01853 ansA ansA 1704995 1705963 - Asparaginase Cytoplasm%3B Hydrolase%3B Belongs to the asparaginase 1 family%3B Contains 1 asparaginase/glutaminase domain%3B KEGG: bli:BL02224 L-asparaginase gene gene1852 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01853 S100141_01854 S100141_01854 S100141_01854 1706073 1707068 - Thioredoxin-disulfide reductase KEGG: bld:BLi02434 thioredoxin reductase (NADPH) gene gene1853 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01854 S100141_01855 S100141_01855 gudB gudB 1707128 1708402 - Glutamate dehydrogenase NAD%3B Oxidoreductase%3B GudB seems to be intrinsically inactive%2C however spontaneous mutations removing a 9-bp direct repeat within the wild-type gudB sequence activated the GudB protein and allowed more-efficient utilization of amino acids of the glutamate family. This insertion presumably causes severe destabilization of the fold of the protein%2C leading to an inactive enzyme that is very quickly degraded. The cryptic GudB serves as a buffer that may compensate for mutations in the rocG gene and that can also be decryptified for the utilization of glutamate as a single carbon source in the absence of arginine. It is unable to synthesize glutamate%3B Belongs to the Glu/Leu/Phe/Val dehydrogenases family%3B KEGG: bli:BL02226 glutamate dehydrogenase gene gene1854 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01855 S100141_01856 S100141_01856 S100141_01856 1708598 1709182 - Adapter protein MecA Competence%3B Sporulation%3B Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed%2C inhibits sporulation. Also involved in Spx degradation by ClpC (By similarity)%3B Belongs to the MecA family gene gene1855 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01856 S100141_01857 S100141_01857 S100141_01857 1709336 1710121 - uncharacterized protein ATP-binding%3B Nucleotide-binding%3B Signal. gene gene1856 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01857 S100141_01858 S100141_01858 S100141_01858 1710200 1710652 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1857 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01858 S100141_01859 S100141_01859 S100141_01859 1710711 1711490 - uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix%3B overlaps another CDS with the same product name gene gene1858 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01859 S100141_01860 S100141_01860 S100141_01860 1711432 1712076 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B overlaps another CDS with the same product name gene gene1859 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01860 S100141_01861 S100141_01861 S100141_01861 1712070 1713566 - DNA helicase ATP-binding%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B DNA helicase%3B Belongs to the helicase family. RecQ subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bli:BL02232 ATP-dependent DNA helicase RecQ%3B overlaps another CDS with the same product name gene gene1860 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01861 S100141_01862 S100141_01862 S100141_01862 1713559 1714653 - DNA helicase KEGG: drm:Dred_1261 ATP-dependent DNA helicase RecQ%3B overlaps another CDS with the same product name gene gene1861 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01862 S100141_01863 S100141_01863 S100141_01863 1714881 1715129 + Ferredoxin 4Fe-4S%3B Electron transport%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Repeat%3B Transport%3B Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. This ferredoxin may act as a phosphodonor to cytochrome P450 BioI%3B Contains 1 4Fe-4S ferredoxin-type domain gene gene1862 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01863 S100141_01864 S100141_01864 S100141_01864 1715283 1715861 - Riboflavin transporter FmnP Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mediates uptake of riboflavin and roseoflavin%2C a toxic riboflavin analo%3B may also transport FMN. Probably a riboflavin- binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane%2C not extracytoplasmic soluble proteins (By similarity)%3B Belongs to the prokaryotic riboflavin transporter (P- RFT) (TC 2. A. 87) family gene gene1863 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01864 S100141_01865 S100141_01865 serA serA 1716404 1717981 + Phosphoglycerate dehydrogenase Amino-acid biosynthesis%3B NAD%3B Oxidoreductase%3B Serine biosynthesis%3B Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU23070 D-3-phosphoglycerate dehydrogenase gene gene1864 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01865 S100141_01866 S100141_01866 lytM lytM 1718030 1718854 - Lysostaphin Cell membrane%3B Hydrolase%3B Membrane%3B Metal-binding%3B Metalloprotease%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Zinc%3B Belongs to the peptidase M23B family%3B KEGG: har:HEAR2799 lysostaphin gene gene1865 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01866 S100141_01867 S100141_01867 S100141_01867 1718979 1719905 - Sigma-X negative effector Cell membrane%3B Membrane%3B Repressor%3B Transcription%3B Transcription regulation. gene gene1866 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01867 S100141_01868 S100141_01868 S100141_01868 1720021 1720605 - RNA polymerase sigma factor SigX Cell membrane%3B DNA-binding%3B Membrane%3B Sigma factor%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. May be involved in the regulation of iron metabolism. Belongs to the sigma-70 factor family. ECF subfamily gene gene1867 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01868 S100141_01869 S100141_01869 S100141_01869 1720880 1721794 - Transcriptional regulator LytR Cell membrane%3B Membrane%3B Signal-anchor%3B Transcription%3B Transcription regulation%3B Transmembrane%3B Transmembrane helix%3B Attenuator role for operon expression%3B Belongs to the LytR/CpsA/Psr regulatory protein family gene gene1868 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01869 S100141_01870 S100141_01870 pdaA pdaA 1722004 1722570 - Chitooligosaccharide deacetylase Cytoplasm%3B Hydrolase%3B Metal-binding%3B Nodulation%3B Is involved in generating a small heat-stable compound (Nod)%2C an acylated oligomer of N-acetylglucosamine%2C that stimulates mitosis in various plant protoplasts. Belongs to the polysaccharide deacetylase family%3B KEGG: rho:RHOM_06145 peptidoglycan-N-acetylmuramic acid deacetylase%3B In linear amides gene gene1869 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01870 S100141_01871 S100141_01871 S100141_01871 1722991 1724124 - hypothetical protein gene gene1870 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01871 S100141_01872 S100141_01872 S100141_01872 1724121 1725572 - Sensor protein VanSB Antibiotic resistance%3B ATP-binding%3B Cell membrane%3B Cell wall biogenesis/degradation%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system VanS/VanR. Activates the transcription of vanH%2C vanA and vanX in response to vancomycin which results in vancomycin resistance. VanS activates VanR by phosphorylation. Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: gme:Gmet_2737 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene1871 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01872 S100141_01873 S100141_01873 S100141_01873 1725576 1726277 - Transcriptional regulatory protein ResD Activator%3B Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system ResD/ResE. Required for the expression of resA%2C ctaA%2C qcrABC and fn%3B activation role in global regulation of aerobic and anaerobic respiration%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene1872 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01873 S100141_01874 S100141_01874 resE resE 1726730 1728511 - Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system ResD/ResE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates ResD%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bsu:BSU23110 two-component system%2C OmpR family%2C sensor histidine kinase ResE gene gene1873 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01874 S100141_01875 S100141_01875 S100141_01875 1728508 1729230 - Transcriptional regulatory protein ResD Activator%3B Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system ResD/ResE. Required for the expression of resA%2C ctaA%2C qcrABC and fn%3B activation role in global regulation of aerobic and anaerobic respiration%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene1874 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01875 S100141_01876 S100141_01876 S100141_01876 1729375 1730550 - Cytochrome c bioproteinis protein ResC Cell membrane%3B Cytochrome c-type biogenesis%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Required for the biogenesis of c-type cytochromes%3B Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family gene gene1875 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01876 S100141_01877 S100141_01877 S100141_01877 1730576 1732207 - Cytochrome c bioproteinis protein ResB Cell membrane%3B Cytochrome c-type biogenesis%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Required for the biogenesis of c-type cytochromes gene gene1876 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01877 S100141_01878 S100141_01878 S100141_01878 1732204 1732737 - Thiol-disulfide oxidoreductase ResA Cell membrane%3B Cytochrome c-type biogenesis%3B Disulfide bond%3B Membrane%3B Oxidoreductase%3B Redox-active center%3B Signal-anchor%3B Transmembrane%3B Transmembrane helix%3B Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA%2C leading to breakage of disulfide bonds in apocytochrome%3B following this reduction heme can be covalently attached%3B Belongs to the thioredoxin family. ResA subfamily%3B Contains 1 thioredoxin domain gene gene1877 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01878 S100141_01879 S100141_01879 rluB rluB 1732825 1733559 - 23S rRNA pseudouridine(2605) synthase Isomerase%3B RNA-binding%3B rRNA processing%3B Responsible for synthesis of pseudouridine from uracil- 2633 in 23S ribosomal RNA. Belongs to the pseudouridine synthase RsuA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: sdl:Sdel_0065 23S rRNA pseudouridine2605 synthase gene gene1878 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01879 S100141_01880 S100141_01880 S100141_01880 1733718 1734254 - Spore maturation protein Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Involved in spore core dehydratio%3B might be involved in the transport of something into or out of the forespore or could be required for some modification of the cortex peptidoglycan structure. Belongs to the SpmB family gene gene1879 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01880 S100141_01881 S100141_01881 S100141_01881 1734259 1734846 - Spore maturation protein Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix. gene gene1880 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01881 S100141_01882 S100141_01882 S100141_01882 1734834 1735988 - Serine-type D-Ala-D-Ala carboxypeptidase Carboxypeptidase%3B Cell shape%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Membrane%3B Peptidoglycan synthesis%3B Protease%3B Signal%3B Sporulation%3B Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. Required specifically for the synthesis of the spore form of peptidoglycan (cortex). Belongs to the peptidase S11 family%3B KEGG: bli:BL01881 D-alanyl-D-alanine carboxypeptidase gene gene1881 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01882 S100141_01883 S100141_01883 S100141_01883 1736141 1736632 - uncharacterized protein gene gene1882 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01883 S100141_01884 S100141_01884 S100141_01884 1736747 1737340 - Segregation and condensation protein Cell cycle%3B Cell division%3B Chromosome partition%3B Cytoplasm%3B Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves%3B Belongs to the ScpB family%3B overlaps another CDS with the same product name gene gene1883 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01884 S100141_01885 S100141_01885 S100141_01885 1737330 1738085 - Segregation and condensation protein Cell cycle%3B Cell division%3B Chromosome partition%3B Cytoplasm%3B Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves%3B Belongs to the ScpA family%3B overlaps another CDS with the same product name gene gene1884 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01885 S100141_01886 S100141_01886 S100141_01886 1738268 1738363 + hypothetical protein gene gene1885 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01886 S100141_01887 S100141_01887 S100141_01887 1738484 1739005 + uncharacterized protein gene gene1886 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01887 S100141_01888 S100141_01888 S100141_01888 1739016 1739390 - Protein RibT Acyltransferase%3B Riboflavin biosynthesis%3B Transferase%3B Involved in riboflavin biosynthesis. Contains 1 N-acetyltransferase domain gene gene1887 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01888 S100141_01889 S100141_01889 ribH ribH 1739492 1739956 - 6%2C7-dimethyl-8-ribityllumazine synthase Riboflavin biosynthesis%3B Transferase%3B Catalyzes the formation of 6%2C7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3%2C4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin%3B Belongs to the DMRL synthase family%3B KEGG: bli:BL01888 6%2C7-dimethyl-8-ribityllumazine synthase gene gene1888 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01889 S100141_01890 S100141_01890 S100141_01890 1739991 1741187 - 3%2C4-dihydroxy-2-butanone-4-phosphate synthase GTP-binding%3B Hydrolase%3B Lyase%3B Magnesium%3B Manganese%3B Metal-binding%3B Multifunctional enzyme%3B Nucleotide-binding%3B Riboflavin biosynthesis%3B Zinc%3B Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3%2C4-dihydroxy-2-butanone 4-phosphate%3B Catalyzes the conversion of GTP to 2%2C5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP)%2C formate and pyrophosphate%3B In the N-terminal sectio%3B belongs to the DHBP synthase family%3B In the C-terminal sectio%3B belongs to the GTP cyclohydrolase II family%3B KEGG: bid:Bind_0944 3%2C4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II gene gene1889 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01890 S100141_01891 S100141_01891 ribE ribE 1741209 1741856 - Riboflavin synthase Repeat%3B Riboflavin biosynthesis%3B Transferase%3B Catalyzes the dismutation of two molecules of 6%2C7- dimethyl-8-ribityllumazine%2C resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil%3B Contains 2 lumazine-binding repeats%3B KEGG: hdu:HD1162 riboflavin synthase gene gene1890 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01891 S100141_01892 S100141_01892 ribD ribD 1741868 1742956 - Diaminohydroxyphosphoribosylaminopyrimidine deaminase Hydrolase%3B Metal-binding%3B Multifunctional enzyme%3B NADP%3B Oxidoreductase%3B Riboflavin biosynthesis%3B Zinc%3B Converts 2%2C5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2%2C4(1h%2C3h)- pyrimidinedione 5'-phosphate. In the N-terminal sectio%3B belongs to the cytidine and deoxycytidylate deaminase family%3B In the C-terminal sectio%3B belongs to the HTP reductase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: bli:BL01891 diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase gene gene1891 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01892 S100141_01893 S100141_01893 S100141_01893 1743382 1743660 - uncharacterized protein gene gene1892 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01893 S100141_01894 S100141_01894 S100141_01894 1743923 1746109 - 2'%2C3'-cyclic-nucleotide 3'-phosphodiesterase KEGG: fnu:FN1603 2'%2C3'-cyclic-nucleotide 3'-phosphodiesterase gene gene1893 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01894 S100141_01895 S100141_01895 S100141_01895 1746236 1746673 - Small heat shock protein C2 Stress response%3B Belongs to the small heat shock protein (HSP20) family gene gene1894 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01895 S100141_01896 S100141_01896 S100141_01896 1746832 1747137 - hypothetical protein gene gene1895 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01896 S100141_01897 S100141_01897 rapA rapA 1747127 1748257 - Response regulator aspartate phosphatase Hydrolase%3B Protein phosphatase%3B Repeat%3B TPR repeat%3B Belongs to the RAP family%3B Contains 5 TPR repeats%3B KEGG: bli:BL05244 response regulator aspartate phosphatase A (stage 0 sporulation protein L)%3B Acting on ester bonds gene gene1896 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01897 S100141_01898 S100141_01898 ppiB ppiB 1748488 1748925 - Peptidylprolyl isomerase Cytoplasm%3B Isomerase%3B Rotamase%3B PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Belongs to the cyclophilin-type PPIase family%3B Contains 1 PPIase cyclophilin-type domain%3B KEGG: bli:BL05245 peptidyl-prolyl cis-trans isomerase B (cyclophilin B) gene gene1897 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01898 S100141_01899 S100141_01899 S100141_01899 1749262 1750158 + uncharacterized protein gene gene1898 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01899 S100141_01900 S100141_01900 S100141_01900 1750155 1751015 - UPF0714 protein YndL Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0714 family gene gene1899 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01900 S100141_01901 S100141_01901 lysA lysA 1751254 1752573 - Diaminopimelate decarboxylase Amino-acid biosynthesis%3B Decarboxylase%3B Lyase%3B Lysine biosynthesis%3B Pyridoxal phosphate%3B Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine%3B Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily%3B KEGG: bsu:BSU23380 diaminopimelate decarboxylase gene gene1900 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01901 S100141_01902 S100141_01902 S100141_01902 1752937 1753266 + hypothetical protein gene gene1901 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01902 S100141_01903 S100141_01903 S100141_01903 1753311 1754783 - Stage V sporulation protein AF Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Belongs to the GerABKA family gene gene1902 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01903 S100141_01904 S100141_01904 S100141_01904 1754743 1755345 - Stage V sporulation protein AE Sporulation. gene gene1903 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01904 S100141_01905 S100141_01905 S100141_01905 1755352 1755702 - Stage V sporulation protein AEB Sporulation. gene gene1904 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01905 S100141_01906 S100141_01906 S100141_01906 1755704 1756723 - Stage V sporulation protein AD Sporulation. gene gene1905 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01906 S100141_01907 S100141_01907 S100141_01907 1756736 1757185 - Stage V sporulation protein AC Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix. gene gene1906 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01907 S100141_01908 S100141_01908 S100141_01908 1757199 1757624 - Stage V sporulation protein Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix. gene gene1907 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01908 S100141_01909 S100141_01909 S100141_01909 1757614 1758234 - Stage V sporulation protein AA Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix. gene gene1908 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01909 S100141_01910 S100141_01910 S100141_01910 1758402 1759169 - RNA polymerase sigma-F factor DNA-binding%3B Sigma factor%3B Sporulation%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes. Belongs to the sigma-70 factor family gene gene1909 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01910 S100141_01911 S100141_01911 S100141_01911 1759182 1759622 - Non-specific serine/threonine protein kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Serine/threonine-protein kinase%3B Sporulation%3B Transferase%3B Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition%3B Belongs to the anti-sigma-factor family%3B KEGG: bsu:BSU23460 stage II sporulation protein AB (anti-sigma F factor) gene gene1910 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01911 S100141_01912 S100141_01912 S100141_01912 1759619 1759972 - Anti-sigma F factor antagonist Phosphoprotein%3B Sporulation%3B In the phosphorylated form it could act as an anti-anti- sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition%3B Belongs to the anti-sigma-factor antagonist family%3B Contains 1 STAS domain gene gene1911 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01912 S100141_01913 S100141_01913 dacC dacC 1760066 1761238 - Serine-type D-Ala-D-Ala carboxypeptidase Carboxypeptidase%3B Cell shape%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Peptidoglycan synthesis%3B Protease%3B Secreted%3B Signal%3B Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. Belongs to the peptidase S11 family%3B KEGG: bli:BL00775 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6) gene gene1912 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01913 S100141_01914 S100141_01914 punA punA 1761396 1762211 - Purine-nucleoside phosphorylase Glycosyltransferase%3B Phosphoprotein%3B Transferase%3B The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules%2C with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine%2C inosine%2C 2'-deoxyguanosine and 2'-deoxyinosine%3B Belongs to the PNP/MTAP phosphorylase family%3B KEGG: bli:BL00774 purine-nucleoside phosphorylase gene gene1913 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01914 S100141_01915 S100141_01915 deoB deoB 1762223 1763407 - Phosphopentomutase Cytoplasm%3B Isomerase%3B Manganese%3B Metal-binding%3B Phosphotransfer between the C1 and C5 carbon atoms of pentose%3B Belongs to the phosphopentomutase family%3B KEGG: bli:BL00772 phosphopentomutase gene gene1914 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01915 S100141_01916 S100141_01916 S100141_01916 1763601 1764491 - Tyrosine recombinase XerD Cell cycle%3B Cell division%3B Chromosome partition%3B Cytoplasm%3B DNA integration%3B DNA recombination%3B DNA-binding%3B Site-specific tyrosine recombinase%2C which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids%3B Belongs to the 'phage' integrase family. XerD subfamily gene gene1915 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01916 S100141_01917 S100141_01917 S100141_01917 1764498 1764722 - putative membrane protein YqzK Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1916 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01917 S100141_01918 S100141_01918 S100141_01918 1764843 1765292 - Ferric uptake regulation protein Cytoplasm%3B DNA-binding%3B Iron%3B Metal-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Zinc%3B Iron uptake repressor. Acts on the transcription of ferri-siderophore uptake genes. Belongs to the Fur family gene gene1917 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01918 S100141_01919 S100141_01919 S100141_01919 1765411 1766067 - Stage II sporulation protein Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane gene gene1918 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01919 S100141_01920 S100141_01920 S100141_01920 1766181 1767527 - Cellobiose permease IIC component Cell membrane%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in cellobiose transport. Contains 1 PTS EIIC type-3 domain gene gene1919 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01920 S100141_01921 S100141_01921 celA celA 1767547 1767846 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cytoplasm%3B Kinase%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in cellobiose transport. Contains 1 PTS EIIB type-3 domain%3B KEGG: eoj:ECO26_2139 PTS system%2C cellobiose-specific IIB component gene gene1920 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01921 S100141_01922 S100141_01922 S100141_01922 1768111 1769034 + Nicotinamide riboside transporter Cell membrane%3B Membrane%3B Phosphoprotein%3B Transmembrane%3B Transmembrane helix%3B Transport%3B High-affinity pH-dependent nicotinamide riboside transporter which also transports thiamine with low affinity. Involved in 5-fluorocytosine sensitivity%3B Belongs to the purine-cytosine permease (2. A. 39) family gene gene1921 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01922 S100141_01923 S100141_01923 S100141_01923 1768995 1769585 + putative allantoin permease Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Transport of allantoin%3B Belongs to the purine-cytosine permease (2. A. 39) family gene gene1922 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01923 S100141_01924 S100141_01924 S100141_01924 1769706 1770362 + Ribosomal-protein-serine acetyltransferase Acyltransferase%3B Cytoplasm%3B Transferase%3B This enzyme acetylates the N-terminal serine of ribosomal protein L7/L12. Belongs to the acetyltransferase family. RimL subfamily%3B Contains 1 N-acetyltransferase domain%3B KEGG: bce:BC2017 null%3B Transferring groups other than amino-acyl groups gene gene1923 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01924 S100141_01925 S100141_01925 S100141_01925 1770199 1770570 - uncharacterized protein gene gene1924 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01925 S100141_01926 S100141_01926 S100141_01926 1770635 1771087 - Protein ElaA Belongs to the UPF0039 (ElaA) family%3B Contains 1 N-acetyltransferase domain gene gene1925 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01926 S100141_01927 S100141_01927 S100141_01927 1771109 1772272 - uncharacterized protein To M. jannaschii MJ0043 N-terminal region gene gene1926 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01927 S100141_01928 S100141_01928 nudF nudF 1772269 1772835 - ADP-ribose diphosphatase Hydrolase%3B Magnesium%3B Metal-binding%3B Acts on ADP-mannose and ADP-glucose as well as ADP- ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process (By similarity)%3B Belongs to the Nudix hydrolase family. NudF subfamily%3B Contains 1 nudix hydrolase domain%3B KEGG: bli:BL05253 ADP-ribose pyrophosphatase gene gene1927 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01928 S100141_01929 S100141_01929 S100141_01929 1772903 1773079 + hypothetical protein gene gene1928 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01929 S100141_01930 S100141_01930 S100141_01930 1773130 1773735 + putative HTH-type transcriptional regulator YdgC DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH tetR-type DNA-binding domain gene gene1929 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01930 S100141_01931 S100141_01931 S100141_01931 1773741 1774088 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1930 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01931 S100141_01932 S100141_01932 S100141_01932 1774162 1775082 + putative oxidoreductase YqkF NADP%3B Oxidoreductase%3B Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily gene gene1931 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01932 S100141_01933 S100141_01933 S100141_01933 1775125 1775358 - uncharacterized protein gene gene1932 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01933 S100141_01934 S100141_01934 S100141_01934 1775515 1776444 + uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1933 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01934 S100141_01935 S100141_01935 S100141_01935 1776468 1776707 - uncharacterized protein gene gene1934 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01935 S100141_01936 S100141_01936 S100141_01936 1776721 1777044 - uncharacterized protein gene gene1935 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01936 S100141_01937 S100141_01937 S100141_01937 1777153 1777350 + hypothetical protein gene gene1936 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01937 S100141_01938 S100141_01938 S100141_01938 1777366 1778337 - UPF0157 protein YqkA Acyltransferase%3B Transferase%3B In the C-terminal sectio%3B belongs to the UPF0157 (GrpB) family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK3057 null%3B Transferring groups other than amino-acyl groups gene gene1937 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01938 S100141_01939 S100141_01939 S100141_01939 1778334 1778702 - Glutathione transferase Contains 1 ABM domain%3B KEGG: thi:THI_2919 glutathione S-transferase gene gene1938 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01939 S100141_01940 S100141_01940 S100141_01940 1779270 1779884 + Triacylglycerol lipase Hydrolase%3B Lipid degradation%3B Lipid metabolism%3B Secreted%3B Signal%3B Active toward p-nitrophenyl esters and triacylglycerides with a marked preference for esters with C8 acyl groups%3B Belongs to the AB hydrolase superfamily%3B KEGG: bli:BL05255 triacylglycerol lipase gene gene1939 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01940 S100141_01941 S100141_01941 S100141_01941 1780030 1780242 - hypothetical protein gene gene1940 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01941 S100141_01942 S100141_01942 S100141_01942 1780512 1782041 + Periplasmic dipeptide transport protein Chemotaxis%3B Disulfide bond%3B Peptide transport%3B Periplasm%3B Protein transport%3B Signal%3B Transport%3B Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis. Belongs to the bacterial solute-binding protein 5 family gene gene1941 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01942 S100141_01943 S100141_01943 S100141_01943 1782038 1782979 + Putative oligopeptide transport system permease protein oppB2 Cell membrane%3B Membrane%3B Peptide transport%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of a transport system that may be involved in oligopeptide uptake. Probably responsible for the translocation of the substrate across the membrane. Important for S. aureus growth and survival during the infection process (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1942 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01943 S100141_01944 S100141_01944 S100141_01944 1782976 1783797 + Dipeptide transport system permease protein DppC Cell membrane%3B Membrane%3B Peptide transport%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system for dipeptide%3B probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1943 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01944 S100141_01945 S100141_01945 S100141_01945 1783799 1784641 + Oligopeptide transport ATP-binding protein OppD ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Peptide transport%3B Protein transport%3B Transport%3B Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene1944 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01945 S100141_01946 S100141_01946 S100141_01946 1784641 1786440 + putative iron transport system ATP-binding protein ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of an ATP-driven transport system HI_0359/HI_0360/HI_0361/HI_0362 for iron. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene1945 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01946 S100141_01947 S100141_01947 S100141_01947 1786463 1787104 - hypothetical protein gene gene1946 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01947 S100141_01948 S100141_01948 S100141_01948 1787198 1787287 - hypothetical protein gene gene1947 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01948 S100141_01949 S100141_01949 S100141_01949 1787315 1787653 - SPBc2 prophage-derived uncharacterized protein YolD gene gene1948 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01949 S100141_01950 S100141_01950 S100141_01950 1787669 1788931 - Putative UV-damage repair protein UvrX DNA damage%3B DNA repair%3B DNA-binding%3B Magnesium%3B Metal-binding%3B Nucleotidyltransferase%3B Transferase%3B Belongs to the DNA polymerase type-Y family%3B Contains 1 umuC domain gene gene1949 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01950 S100141_01951 S100141_01951 S100141_01951 1789204 1789416 + uncharacterized protein gene gene1950 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01951 S100141_01952 S100141_01952 S100141_01952 1789544 1790782 + putative MFS-type transporter YqjV Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily. TCR/Tet family gene gene1951 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01952 S100141_01953 S100141_01953 S100141_01953 1790833 1791216 - Phosphoglycerate mutase (2%2C3-diphosphoglycerate-independent) KEGG: mlu:Mlut_09490 probable phosphoglycerate mutase gene gene1952 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01953 S100141_01954 S100141_01954 coaA coaA 1791231 1792190 - Pantothenate kinase ATP-binding%3B Coenzyme A biosynthesis%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the prokaryotic pantothenate kinase family%3B KEGG: psy:PCNPT3_12895 type I pantothenate kinase gene gene1953 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01954 S100141_01955 S100141_01955 S100141_01955 1792451 1793416 - hypothetical protein gene gene1954 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01955 S100141_01956 S100141_01956 S100141_01956 1793394 1794056 - Iron-chelate-transporting ATPase ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of a binding-protein-dependent transport system for arginine. Probably responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: aap:NT05HA_1149 iron complex transport system ATP-binding protein gene gene1955 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01956 S100141_01957 S100141_01957 S100141_01957 1794172 1794660 - hypothetical protein gene gene1956 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01957 S100141_01958 S100141_01958 S100141_01958 1795082 1795342 + hypothetical protein gene gene1957 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01958 S100141_01959 S100141_01959 S100141_01959 1795648 1796154 - hypothetical protein gene gene1958 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01959 S100141_01960 S100141_01960 S100141_01960 1796208 1796930 - UPF0714 protein YmaC Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0714 family gene gene1959 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01960 S100141_01961 S100141_01961 S100141_01961 1797361 1798143 - Hydroxysteroid 11-beta-dehydrogenase 1-like protein NADP%3B Oxidoreductase%3B Secreted%3B Signal%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family gene gene1960 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01961 S100141_01962 S100141_01962 gloB gloB 1798153 1799106 - Hydroxyacylglutathione hydrolase Hydrolase%3B Metal-binding%3B Zinc%3B Belongs to the metallo-beta-lactamase superfamily%3B KEGG: nph:NP_3944A hydroxyacylglutathione hydrolase gene gene1961 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01962 S100141_01963 S100141_01963 S100141_01963 1799496 1800317 + Pyrroline-5-carboxylate reductase Amino-acid biosynthesis%3B Cytoplasm%3B NADP%3B Oxidoreductase%3B Proline biosynthesis%3B Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline%3B Belongs to the pyrroline-5-carboxylate reductase family%3B KEGG: bsu:BSU23800 pyrroline-5-carboxylate reductase gene gene1962 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01963 S100141_01964 S100141_01964 S100141_01964 1800376 1801980 - uncharacterized protein To B. subtilis RocB gene gene1963 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01964 S100141_01965 S100141_01965 S100141_01965 1802107 1803186 + NADPH dehydrogenase Detoxification%3B Flavoprotein%3B FMN%3B NADP%3B Oxidoreductase%3B Catalyzes the reduction of the double bond of an array of alpha%2Cbeta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes%3B Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily%3B KEGG: bli:BL00797 NADPH2 dehydrogenase gene gene1964 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01965 S100141_01966 S100141_01966 S100141_01966 1803307 1804737 + hypothetical protein gene gene1965 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01966 S100141_01967 S100141_01967 S100141_01967 1804848 1805609 + uncharacterized protein gene gene1966 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01967 S100141_01968 S100141_01968 S100141_01968 1805643 1805792 - 50S ribosomal protein L33 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L33P family gene gene1967 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01968 S100141_01969 S100141_01969 S100141_01969 1805912 1806835 - Ribonuclease Z Endonuclease%3B Hydrolase%3B Metal-binding%3B Nuclease%3B tRNA processing%3B Zinc%3B Zinc phosphodiesterase%2C which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation%2C by removing a 3'-trailer from precursor tRNA%3B Belongs to the RNase Z family%3B KEGG: ebi:EbC_43140 ribonuclease Z gene gene1968 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01969 S100141_01970 S100141_01970 g6pD g6pD 1807054 1808532 + Glucose-6-phosphate dehydrogenase (NADP(+)) Carbohydrate metabolism%3B Glucose metabolism%3B NADP%3B Oxidoreductase%3B Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone%3B Belongs to the glucose-6-phosphate dehydrogenase family%3B KEGG: bli:BL01964 glucose-6-phosphate 1-dehydrogenase gene gene1969 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01970 S100141_01971 S100141_01971 S100141_01971 1808568 1810532 - Putative TRAP transporter large permease protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the TRAP transporter large permease family gene gene1970 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01971 S100141_01972 S100141_01972 S100141_01972 1810525 1811043 - hypothetical protein gene gene1971 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01972 S100141_01973 S100141_01973 S100141_01973 1811145 1812134 - 31 kDa immunogenic protein Signal. gene gene1972 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01973 S100141_01974 S100141_01974 S100141_01974 1812381 1813094 - Arabinose metabolism transcriptional repressor Cytoplasm%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcriptional repressor of the arabinose utilization genes%3B Contains 1 HTH gntR-type DNA-binding domain gene gene1973 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01974 S100141_01975 S100141_01975 bglA bglA 1813214 1814629 - 6-phospho-beta-glucosidase Disulfide bond%3B Glycoprotein%3B Glycosidase%3B Hydrolase%3B Signal%3B Belongs to the glycosyl hydrolase 1 family%3B KEGG: bli:BL00115 6-phospho-beta-glucosidase gene gene1974 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01975 S100141_01976 S100141_01976 S100141_01976 1814645 1815961 - Oligo-beta-mannoside permease IIC component Cell membrane%3B Membrane%3B Phosphotransferase system%3B Polysaccharide transport%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in the transport of oligo- glucomannans such as cellobiose or mannobiose (Probable)%3B Contains 1 PTS EIIC type-3 domain gene gene1975 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01976 S100141_01977 S100141_01977 celC celC 1816001 1816333 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cytoplasm%3B Kinase%3B Phosphotransferase system%3B Polysaccharide transport%3B Sugar transport%3B Transferase%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in the transport of oligo- glucomannans such as cellobiose or mannobiose (Probable)%3B Contains 1 PTS EIIA type-3 domain%3B KEGG: bli:BL05259 PTS system%2C cellobiose-specific IIA component gene gene1976 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01977 S100141_01978 S100141_01978 S100141_01978 1816339 1816647 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cytoplasm%3B Kinase%3B Phosphotransferase system%3B Polysaccharide transport%3B Sugar transport%3B Transferase%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in the transport of oligo- glucomannans such as cellobiose or mannobiose (Probable)%3B Contains 1 PTS EIIB type-3 domain%3B KEGG: eca:ECA3645 PTS system%2C cellobiose-specific IIB component gene gene1977 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01978 S100141_01979 S100141_01979 S100141_01979 1816797 1818458 - Alkaline phosphatase Hydrolase%3B Magnesium%3B Metal-binding%3B Phosphoprotein%3B Signal%3B Zinc%3B Belongs to the alkaline phosphatase family%3B KEGG: bli:BL01381 alkaline phosphatase gene gene1978 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01979 S100141_01980 S100141_01980 S100141_01980 1818598 1819383 - Glucose 1-dehydrogenase (NAD(P)(+)) NADP%3B Oxidoreductase%3B Stress response%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bli:BL01382 glucose 1-dehydrogenase gene gene1979 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01980 S100141_01981 S100141_01981 gntZ gntZ 1819501 1820910 - Phosphogluconate dehydrogenase (NADP(+)-dependent%2C decarboxylating) Gluconate utilization%3B NADP%3B Oxidoreductase%3B Pentose shunt%3B Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2)%2C with concomitant reduction of NADP to NADPH%3B Belongs to the 6-phosphogluconate dehydrogenase family%3B KEGG: eco:b2029 6-phosphogluconate dehydrogenase gene gene1980 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01981 S100141_01982 S100141_01982 dpo4 dpo4 1820997 1822253 - DNA-directed DNA polymerase Cytoplasm%3B DNA damage%3B DNA repair%3B DNA replication%3B DNA-binding%3B DNA-directed DNA polymerase%3B Magnesium%3B Metal-binding%3B Mutator protein%3B Nucleotidyltransferase%3B Transferase%3B Poorly processive%2C error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks%2C which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis%2C in conjunction with the beta clamp from PolIII (By similarity)%3B Belongs to the DNA polymerase type-Y family%3B Contains 1 umuC domain%3B KEGG: bli:BL01384 DNA polymerase IV gene gene1981 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01982 S100141_01983 S100141_01983 S100141_01983 1822334 1822621 + Membrane protein insertion and folding monitor Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Sensor protein that upregulates translation of the secondary membrane protein insertase (MisCB/YqjG) when activity of the primary membrane protein insertase (MisCA/SpoIIIJ) is limited. Acts as a ribosome-nascent chain complex. When the primary membrane protein insertase activity or level is reduced%2C the membrane insertion of MifM is impaired%2C which induces arrest of MifM translation and unfolding of the mRNA hairpin. Unfolding leads to translation of the downstream gene%2C which encodes the secondary membrane protein insertase MisCB/YqjG. Translation arrest of MifM is mediated by interaction of its C-terminal domain with the ribosomal polypeptide exit tunnel. Undergoes multisite stalling%2C which may allow a sufficient duration of ribosomal stalling and consequently sufficient levels of MisCB/YqjG gene gene1982 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01983 S100141_01984 S100141_01984 S100141_01984 1822670 1823494 + Membrane protein insertase MisCB Cell membrane%3B Chaperone%3B Lipoprotein%3B Membrane%3B Palmitate%3B Protein transport%3B Signal%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex%2C as well as at least some lipoproteins (By similarity). Also involved in protein secretion processes. It has an overlapping%2C although partly distinct%2C function compared to SpoIIIJ(MisCB)%3B Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily gene gene1983 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01984 S100141_01985 S100141_01985 S100141_01985 1823655 1824773 - Propionyl-CoA carboxylase Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Zinc%3B Could be a peptidase. Belongs to the peptidase M20A family%3B KEGG: bya:BANAU_2374 propionyl-CoA carboxylase beta chain gene gene1984 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01985 S100141_01986 S100141_01986 S100141_01986 1824794 1826323 - Propionyl-CoA carboxylase ATP-binding%3B Ligase%3B Nucleotide-binding%3B Belongs to the AccD/PCCB family%3B Contains 1 carboxyltransferase domain%3B KEGG: bli:BL01386 propionyl-CoA carboxylase beta chain gene gene1985 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01986 S100141_01987 S100141_01987 S100141_01987 1826658 1827629 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1986 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01987 S100141_01988 S100141_01988 S100141_01988 1827690 1828418 - Polar-amino-acid-transporting ATPase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3. A. 1. 11. 1) family%3B Contains 1 ABC transporter domain%3B KEGG: sty:STY1436 polar amino acid transport system ATP-binding protein gene gene1987 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01988 S100141_01989 S100141_01989 S100141_01989 1828405 1829067 - Arginine transport system permease protein ArtQ Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of a binding-protein-dependent transport system for arginine. Probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1988 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01989 S100141_01990 S100141_01990 S100141_01990 1829156 1829923 - putative amino-acid-binding protein YxeM Amino-acid transport%3B Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S- methylcysteine. Belongs to the bacterial solute-binding protein 3 family gene gene1989 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01990 S100141_01991 S100141_01991 S100141_01991 1829974 1830147 - hypothetical protein gene gene1990 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01991 S100141_01992 S100141_01992 S100141_01992 1830147 1830584 - UPF0403 protein Belongs to the UPF0403 family gene gene1991 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01992 S100141_01993 S100141_01993 dagK dagK 1830766 1831668 + Diacylglycerol kinase (ATP) ATP-binding%3B Kinase%3B Lipid biosynthesis%3B Lipid metabolism%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG). In fact%2C is not able to exhibit diacylglycerol kinase activity in vitro. Belongs to the diacylglycerol/lipid kinase family%3B Contains 1 DAGKc domain%3B KEGG: ssd:SPSINT_1652 diacylglycerol kinase (ATP) gene gene1992 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01993 S100141_01994 S100141_01994 bkdB bkdB 1831689 1832969 - Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase Acyltransferase%3B Glycolysis%3B Lipoyl%3B Transferase%3B The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1)%2C lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: bsu:BSU24030 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) gene gene1993 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01994 S100141_01995 S100141_01995 S100141_01995 1832993 1833976 - 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) Oxidoreductase%3B Thiamine pyrophosphate%3B KEGG: sur:STAUR_4870 2-oxoisovalerate dehydrogenase E1 component beta subunit gene gene1994 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01995 S100141_01996 S100141_01996 S100141_01996 1833989 1834981 - 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) Magnesium%3B Metal-binding%3B Oxidoreductase%3B Thiamine pyrophosphate%3B The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1)%2C lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the BCKDHA family%3B KEGG: bli:BL01504 2-oxoisovalerate dehydrogenase E1 component alpha subunit gene gene1995 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01996 S100141_01997 S100141_01997 S100141_01997 1835004 1836425 - Glutathione-disulfide reductase Cytoplasm%3B Disulfide bond%3B FAD%3B Flavoprotein%3B Glycolysis%3B NAD%3B Oxidoreductase%3B Redox-active center%3B The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of 3 enzymatic components: branched-chain alpha-keto acid decarboxylase (E1)%2C lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: abo:ABO_1423 glutathione reductase (NADPH) gene gene1996 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01997 S100141_01998 S100141_01998 S100141_01998 1836415 1837521 - Butyrate kinase ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the acetokinase family%3B KEGG: bli:BL01502 butyrate kinase gene gene1997 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01998 S100141_01999 S100141_01999 S100141_01999 1837560 1838654 - Leucine dehydrogenase Branched-chain amino acid catabolism%3B NAD%3B Oxidoreductase%3B Catalyzes the reversible deamination of L-leucine to 4- methyl-2-oxopentanoate. Can also use other substrates such as L- isoleucine%2C L-valine and L-2-aminobutyrate. The 2-oxo analogs of branched-chain and straight-chain amino acids serve as good substrates for the reverse reaction%3B Belongs to the Glu/Leu/Phe/Val dehydrogenases family%3B KEGG: bsu:BSU24080 leucine dehydrogenase gene gene1998 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_01999 S100141_02000 S100141_02000 S100141_02000 1838658 1839569 - Phosphate butyryltransferase Acyltransferase%3B Transferase%3B Catalyzes the conversion of butyryl-CoA through butyryl phosphate to butyrate. Belongs to the phosphate acetyltransferase and butyryltransferase family%3B KEGG: bli:BL01500 phosphate butyryltransferase gene gene1999 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02000 S100141_02001 S100141_02001 dctS dctS 1839696 1841765 - Histidine kinase ATP-binding%3B Cell membrane%3B DNA-binding%3B Membrane%3B Nucleotide-binding%3B Repeat%3B Transcription%3B Transcription regulation%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Contains 1 PAC (PAS-associated C-terminal) domain%3B Contains 2 PAS (PER-ARNT-SIM) domains%3B Contains 1 sigma-54 factor interaction domain%3B KEGG: amt:Amet_2967 two-component system%2C CitB family%2C sensor histidine kinase DctS gene gene2000 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02001 S100141_02002 S100141_02002 S100141_02002 1841916 1842170 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2001 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02002 S100141_02003 S100141_02003 S100141_02003 1842221 1842946 - Glycerophosphodiester phosphodiesterase Contains 1 GP-PDE domain%3B KEGG: pgb:H744_1c0275 glycerophosphoryl diester phosphodiesterase gene gene2002 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02003 S100141_02004 S100141_02004 S100141_02004 1843080 1843700 - N-acetylmuramoyl-L-alanine amidase Hydrolase%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B KEGG: bli:BL01514 N-acetylmuramoyl-L-alanine amidase gene gene2003 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02004 S100141_02005 S100141_02005 S100141_02005 1843736 1844056 - Membrane-bound protein LytA Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal. gene gene2004 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02005 S100141_02006 S100141_02006 cysE cysE 1844596 1844925 - Serine O-acetyltransferase Acyltransferase%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Magnesium%3B Metal-binding%3B Multifunctional enzyme%3B Nucleotidyltransferase%3B Peptidoglycan synthesis%3B Repeat%3B Transferase%3B Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P)%2C which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate)%2C a reaction catalyzed by the N-terminal domain%3B In the N-terminal sectio%3B belongs to the N- acetylglucosamine-1-phosphate uridyltransferase family%3B In the C-terminal sectio%3B belongs to the transferase hexapeptide repeat family%3B KEGG: blh:BaLi_c26760 serine O-acetyltransferase gene gene2005 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02006 S100141_02007 S100141_02007 S100141_02007 1845055 1845351 - hypothetical protein gene gene2006 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02007 S100141_02008 S100141_02008 S100141_02008 1845724 1846524 - Stage 0 sporulation protein Activator%3B Calcium%3B Cytoplasm%3B DNA-binding%3B Metal-binding%3B Phosphoprotein%3B Repressor%3B Sporulation%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB%2C activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box) (By similarity)%3B Contains 1 response regulatory domain gene gene2007 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02008 S100141_02009 S100141_02009 S100141_02009 1846814 1848154 - SpoIVB peptidase Hydrolase%3B Protease%3B Serine protease%3B Signal%3B Sporulation%3B Zymogen%3B Plays a central role in the sigma-K checkpoint which coordinates gene expression during the later stages of spore formation. The protease is activated by trans cleavage of the zymogen precursor producing SpoIVB-45 kDa. This undergoes further trimming by cis cleavage to form SpoIVB-43 kDa and SpoIVB-42 kDa. The protease then cleaves the C-terminus of the SpoIVFA metalloprotease activating the latter%3B Contains 1 PDZ (DHR) domain%3B Contains 1 peptidase S55 domain%3B KEGG: bli:BL01519 stage IV sporulation protein B gene gene2008 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02009 S100141_02010 S100141_02010 S100141_02010 1848280 1850010 - DNA repair protein RecN ATP-binding%3B Cytoplasm%3B DNA damage%3B DNA repair%3B Nucleotide-binding%3B Involved in recombinational repair of damaged DNA. Seems to be the first protein recruited to repair centers%2C foci that are the site of double-strand DNA break(s)%2C followed by RecO and then RecF. Belongs to the RecN family gene gene2009 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02010 S100141_02011 S100141_02011 S100141_02011 1850042 1850491 - Arginine repressor Amino-acid biosynthesis%3B Arginine biosynthesis%3B Cytoplasm%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Regulates arginine biosynthesis genes%3B Belongs to the ArgR family gene gene2010 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02011 S100141_02012 S100141_02012 tlyA tlyA 1850657 1851502 - 23S rRNA (cytidine(1920)-2'-O)-methyltransferase Methyltransferase%3B RNA-binding%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B Belongs to the TlyA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: bli:BL01522 23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase gene gene2011 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02012 S100141_02013 S100141_02013 S100141_02013 1851499 1853367 - 1-deoxy-D-xylulose-5-phosphate synthase Isoprene biosynthesis%3B Magnesium%3B Metal-binding%3B Thiamine biosynthesis%3B Thiamine pyrophosphate%3B Transferase%3B Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)%3B Belongs to the transketolase family. DXPS subfamily%3B KEGG: serf:L085_13545 1-deoxy-D-xylulose-5-phosphate synthase gene gene2012 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02013 S100141_02014 S100141_02014 ggpS ggpS 1853634 1854524 - Dimethylallyltranstransferase Carotenoid biosynthesis%3B Chlorophyll biosynthesis%3B Cyanelle%3B Isoprene biosynthesis%3B Magnesium%3B Metal-binding%3B Photosynthesis%3B Plastid%3B Transferase%3B Catalyzes the condensation of farnesyl diphosphate (FPP) and isopentenyl diphosphate (IPP) to yield geranylgeranyl diphosphate (GGPP) needed for biosynthesis of carotenoids and diterpenes%3B Belongs to the FPP/GGPP synthase family%3B KEGG: bli:BL01524 geranylgeranyl diphosphate synthase%2C type II gene gene2013 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02014 S100141_02015 S100141_02015 xseB xseB 1854514 1854774 - Exodeoxyribonuclease VII Cytoplasm%3B Exonuclease%3B Hydrolase%3B Nuclease%3B Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides%2C which are then degraded further into small acid-soluble oligonucleotides%3B Belongs to the XseB family%3B KEGG: bli:BL01525 exodeoxyribonuclease VII small subunit%3B overlaps another CDS with the same product name gene gene2014 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02015 S100141_02016 S100141_02016 xseA xseA 1854767 1856116 - Exodeoxyribonuclease VII Cytoplasm%3B Exonuclease%3B Hydrolase%3B Nuclease%3B Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides%2C which are then degraded further into small acid-soluble oligonucleotides%3B Belongs to the XseA family%3B KEGG: bli:BL01526 exodeoxyribonuclease VII large subunit%3B overlaps another CDS with the same product name gene gene2015 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02016 S100141_02017 S100141_02017 folD folD 1856193 1857047 - Methylenetetrahydrofolate dehydrogenase (NADP(+)) Amino-acid biosynthesis%3B Histidine biosynthesis%3B Hydrolase%3B Methionine biosynthesis%3B Multifunctional enzyme%3B NADP%3B One-carbon metabolism%3B Oxidoreductase%3B Purine biosynthesis%3B Catalyzes the oxidation of 5%2C10- methylenetetrahydrofolate to 5%2C10-methenyltetrahydrofolate and then the hydrolysis of 5%2C10-methenyltetrahydrofolate to 10- formyltetrahydrofolate%3B Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family%3B KEGG: bma:BMA1724 methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase gene gene2016 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02017 S100141_02018 S100141_02018 S100141_02018 1857064 1857453 - N utilization substance protein B like protein Transcription%3B Transcription regulation%3B Transcription termination%3B Involved in the transcription termination process%3B Belongs to the NusB family gene gene2017 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02018 S100141_02019 S100141_02019 S100141_02019 1857746 1858156 - uncharacterized protein Belongs to the asp23 family gene gene2018 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02019 S100141_02020 S100141_02020 S100141_02020 1858177 1859529 - Acetyl-CoA carboxylase ATP-binding%3B Biotin%3B Ligase%3B Magnesium%3B Nucleotide-binding%3B Contains 1 ATP-grasp domain%3B Contains 1 biotin carboxylation domain%3B KEGG: wgl:WIGMOR_0138 acetyl-CoA carboxylase%2C biotin carboxylase subunit gene gene2019 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02020 S100141_02021 S100141_02021 S100141_02021 1859541 1860020 - Biotin carboxyl carrier protein of acetyl-CoA carboxylase Biotin%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B This protein is a component of the acetyl coenzyme A carboxylase comple%3B first%2C biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. Contains 1 biotinyl-binding domain gene gene2020 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02021 S100141_02022 S100141_02022 S100141_02022 1860194 1860832 - Stage III sporulation protein AH Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Involved in forespore engulfment. Forms a channel with SpoIIIAH that is open on the forespore end and closed (or gated) on the mother cell end. This allows sigma-E-directed gene expression in the mother-cell compartment of the sporangium to trigger the activation of sigma-G forespore-specific gene expression by a pathway of intercellular signaling gene gene2021 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02022 S100141_02023 S100141_02023 S100141_02023 1860833 1861528 - Stage III sporulation protein AG Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix. gene gene2022 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02023 S100141_02024 S100141_02024 S100141_02024 1861521 1862150 - Stage III sporulation protein AF Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix. gene gene2023 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02024 S100141_02025 S100141_02025 S100141_02025 1862162 1863367 - Stage III sporulation protein AE Cell membrane%3B Membrane%3B Signal%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Required during sporulation for activation of sigma factor SpoIIIG/SigG after engulfment is completed in the prespore. Overexpression in the absence of SpoIIIJ is synthetically lethal gene gene2024 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02025 S100141_02026 S100141_02026 S100141_02026 1863389 1863754 - Stage III sporulation protein AD Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix. gene gene2025 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02026 S100141_02027 S100141_02027 S100141_02027 1863797 1864003 - Stage III sporulation protein AC Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix. gene gene2026 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02027 S100141_02028 S100141_02028 S100141_02028 1864026 1864541 - Stage III sporulation protein Sporulation. gene gene2027 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02028 S100141_02029 S100141_02029 S100141_02029 1864535 1865458 - Stage III sporulation protein AA ATP-binding%3B Nucleotide-binding%3B Sporulation. gene gene2028 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02029 S100141_02030 S100141_02030 S100141_02030 1865550 1865831 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2029 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02030 S100141_02031 S100141_02031 S100141_02031 1865994 1866551 - Elongation factor P Cytoplasm%3B Elongation factor%3B Protein biosynthesis%3B Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA%2C thus increasing their reactivity as acceptors for peptidyl transferase%3B Belongs to the elongation factor P family gene gene2030 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02031 S100141_02032 S100141_02032 pepP pepP 1866583 1867644 - Xaa-Pro aminopeptidase Hydrolase%3B Manganese%3B Metal-binding%3B Belongs to the peptidase M24B family%3B KEGG: bsu:BSU24460 Xaa-Pro aminopeptidase gene gene2031 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02032 S100141_02033 S100141_02033 aroQ aroQ 1867660 1868097 - 3-dehydroquinate dehydratase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Lyase%3B Catalyzes a trans-dehydration via an enolate intermediate%3B Belongs to the type-II 3-dehydroquinase family%3B KEGG: buh:BUAMB_375 3-dehydroquinate dehydratase II gene gene2032 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02033 S100141_02034 S100141_02034 S100141_02034 1868177 1868713 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2033 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02034 S100141_02035 S100141_02035 S100141_02035 1868965 1869918 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2034 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02035 S100141_02036 S100141_02036 S100141_02036 1869957 1870343 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2035 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02036 S100141_02037 S100141_02037 S100141_02037 1870340 1871215 - uncharacterized protein Cell membrane%3B Hydrolase%3B Lipid degradation%3B Lipid metabolism%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Probable lipid hydrolase%3B Contains 1 patatin domain gene gene2036 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02037 S100141_02038 S100141_02038 S100141_02038 1871549 1871977 - Transcriptional regulator MntR Activator%3B Cytoplasm%3B DNA-binding%3B Manganese%3B Transcription%3B Transcription regulation%3B Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon%3B Contains 1 HTH dtxR-type DNA-binding domain gene gene2037 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02038 S100141_02039 S100141_02039 S100141_02039 1872069 1872905 - Lipoate--protein ligase Acyltransferase%3B Transferase%3B Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH%2C an intermediate carrier during protein lipoylation%3B Belongs to the octanoyltransferase LipM family%3B Contains 1 BPL/LPL catalytic domain%3B KEGG: bsu:BSU24530 lipoate-protein ligase A gene gene2038 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02039 S100141_02040 S100141_02040 glpE glpE 1873092 1873478 + Thiosulfate sulfurtransferase Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Contains 1 rhodanese domain%3B KEGG: pao:Pat9b_3716 thiosulfate sulfurtransferase gene gene2039 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02040 S100141_02041 S100141_02041 S100141_02041 1873644 1874528 - Glycine betaine-binding protein OpuAC Amino-acid transport%3B Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B Involved in a multicomponent binding-protein-dependent transport system for glycine betaine gene gene2040 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02041 S100141_02042 S100141_02042 S100141_02042 1874528 1875382 - Glycine betaine transport system permease protein OpuAB Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in a multicomponent binding-protein-dependent transport system for glycine betain%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2041 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02042 S100141_02043 S100141_02043 proV proV 1875382 1876629 - Quaternary-amine-transporting ATPase Amino-acid transport%3B ATP-binding%3B CBS domain%3B Hydrolase%3B Nucleotide-binding%3B Repeat%3B Transport%3B Involved in a multicomponent binding-protein-dependent transport system for glycine betaine. Probably responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B Contains 2 CBS domains%3B KEGG: bli:BL01559 glycine betaine/proline transport system ATP-binding protein gene gene2042 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02043 S100141_02044 S100141_02044 S100141_02044 1876993 1878450 - Glycine dehydrogenase (aminomethyl-transferring) Oxidoreductase%3B Pyridoxal phosphate%3B The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofacto%3B CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein%3B Belongs to the GcvP family. C-terminal subunit subfamily%3B KEGG: bli:BL01560 glycine dehydrogenase subunit 2%3B overlaps another CDS with the same product name gene gene2043 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02044 S100141_02045 S100141_02045 S100141_02045 1878443 1879789 - Glycine dehydrogenase (aminomethyl-transferring) Oxidoreductase%3B The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofacto%3B CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein%3B Belongs to the GcvP family. N-terminal subunit subfamily%3B KEGG: bsu:BSU24560 glycine dehydrogenase subunit 1%3B overlaps another CDS with the same product name gene gene2044 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02045 S100141_02046 S100141_02046 gcvT gcvT 1879820 1880914 - Aminomethyltransferase Aminotransferase%3B Transferase%3B The glycine cleavage system catalyzes the degradation of glycine%3B Belongs to the GcvT family%3B KEGG: tig:THII_2082 aminomethyltransferase gene gene2045 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02046 S100141_02047 S100141_02047 hepA hepA 1881507 1883186 + putative ATP-dependent helicase YqhH ATP-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Belongs to the SNF2/RAD54 helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: eco:b0059 ATP-dependent helicase HepA%3B Acting on ATP%3B involved in cellular and subcellular movement gene gene2046 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02047 S100141_02048 S100141_02048 S100141_02048 1883193 1883987 + uncharacterized protein gene gene2047 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02048 S100141_02049 S100141_02049 S100141_02049 1884178 1884354 + Protein SinI Acts as an antagonist to SinR. SinI prevents SinR from binding to its target sequence on the gene for AprE (By similarity)%3B Contains 1 Sin domain gene gene2048 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02049 S100141_02050 S100141_02050 S100141_02050 1884382 1884723 + HTH-type transcriptional regulator SinR Activator%3B Bacterial flagellum biogenesis%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Affects autolysin level and flagellation. Contains 1 HTH cro/C1-type DNA-binding domain%3B Contains 1 Sin domain gene gene2049 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02050 S100141_02051 S100141_02051 S100141_02051 1884828 1885622 - Spore coat-associated protein Secreted%3B Signal%3B Sporulation%3B Belongs to the peptidase M73 family gene gene2050 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02051 S100141_02052 S100141_02052 sipW sipW 1885696 1886280 - Signal peptidase I Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Belongs to the peptidase S26B family%3B KEGG: bli:BL01564 signal peptidase%2C endoplasmic reticulum-type%3B Acting on peptide bonds (peptidases) gene gene2051 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02052 S100141_02053 S100141_02053 S100141_02053 1886277 1887005 - uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2052 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02053 S100141_02054 S100141_02054 S100141_02054 1887282 1887602 + uncharacterized protein Signal. gene gene2053 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02054 S100141_02055 S100141_02055 S100141_02055 1887626 1887808 - uncharacterized protein gene gene2054 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02055 S100141_02056 S100141_02056 S100141_02056 1887897 1888262 - ComG operon protein Cell membrane%3B Competence%3B Disulfide bond%3B Membrane%3B Peptidoglycan-anchor%3B Secreted%3B Signal%3B Transport%3B Required for transformation and DNA binding gene gene2055 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02056 S100141_02057 S100141_02057 S100141_02057 1888275 1888763 - ComG operon protein Cell membrane%3B Competence%3B Membrane%3B Required for transformation and DNA binding gene gene2056 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02057 S100141_02058 S100141_02058 S100141_02058 1889003 1889449 - ComG operon protein Cell membrane%3B Competence%3B Membrane%3B Methylation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Required for transformation and DNA binding gene gene2057 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02058 S100141_02059 S100141_02059 S100141_02059 1889446 1889739 - ComG operon protein 3 like protein Cell membrane%3B Competence%3B Disulfide bond%3B Membrane%3B Methylation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Required for transformation and DNA binding%3B Belongs to the ComGC family gene gene2058 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02059 S100141_02060 S100141_02060 S100141_02060 1889753 1890787 - ComG operon protein Cell membrane%3B Competence%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Required for transformation and DNA binding%3B Belongs to the GSP F family%3B overlaps another CDS with the same product name gene gene2059 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02060 S100141_02061 S100141_02061 S100141_02061 1890777 1891841 - ComG operon protein ATP-binding%3B Cell membrane%3B Competence%3B Membrane%3B Nucleotide-binding%3B Transport%3B Required for uptake of DNA by competent cells%3B Belongs to the GSP E family%3B overlaps another CDS with the same product name gene gene2060 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02061 S100141_02062 S100141_02062 S100141_02062 1891998 1892837 - RsbT co-antagonist protein RsbRB Phosphoprotein%3B One of 4 functionally non-identical RsbR paralogs%2C it functions in the environmental signaling branch of the general stress response. Negative regulator of sigma-B activity. Non- phosphorylated RsbS binds to RsbT%2C preventing its association with RsbU. Requires any one of RsbRA%2C RsbRB%2C RsbRC or RsbRD to sequester RsbT. When RsbS and the RsbR paralog(s) are phosphorylated%2C they release RsbT%2C which can then bind and activate RsbU. Contains 1 STAS domain gene gene2061 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02062 S100141_02063 S100141_02063 S100141_02063 1892945 1893016 + tRNA-Gln tRNA gene2062 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02063 S100141_02064 S100141_02064 S100141_02064 1893079 1893456 - Arsenate reductase (glutaredoxin) Activator%3B Cytoplasm%3B Repressor%3B Stress response%3B Transcription%3B Transcription regulation%3B Regulates transcription of a subregulon within the general stress response. Exerts positive and negative effects in response to ethanol stress%3B Belongs to the ArsC family%3B KEGG: bli:BL01574 arsenate reductase gene gene2063 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02064 S100141_02065 S100141_02065 S100141_02065 1893665 1893910 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2064 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02065 S100141_02066 S100141_02066 S100141_02066 1893948 1894586 - Hydroxyacylglutathione hydrolase Hydrolase%3B Metal-binding%3B Zinc%3B Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family%3B KEGG: rha:RHA1_ro06903 hydroxyacylglutathione hydrolase gene gene2065 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02066 S100141_02067 S100141_02067 S100141_02067 1894742 1894915 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2066 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02067 S100141_02068 S100141_02068 S100141_02068 1894976 1895290 - UPF0045 protein YqgV Belongs to the UPF0045 family gene gene2067 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02068 S100141_02069 S100141_02069 S100141_02069 1895306 1896415 - putative lipoprotein YqgU Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal. gene gene2068 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02069 S100141_02070 S100141_02070 yqgT yqgT 1896470 1897594 - Gamma-D-glutamyl-meso-diaminopimelate peptidase Hydrolase%3B Metalloprotease%3B Protease%3B Zinc%3B Belongs to the peptidase M14 family%3B KEGG: bli:BL01578 g-D-glutamyl-meso-diaminopimelate peptidase gene gene2069 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02070 S100141_02071 S100141_02071 S100141_02071 1897736 1898683 - Iron(3+)-hydroxamate-binding protein FhuD Cell membrane%3B Ion transport%3B Iron%3B Iron transport%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B Part of the ABC transporter complex FhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Required for the transport of ferrichrome and coprogen%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene2070 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02071 S100141_02072 S100141_02072 S100141_02072 1898680 1898826 - hypothetical protein gene gene2071 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02072 S100141_02073 S100141_02073 ltaS ltaS 1898852 1900750 - Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase Cell membrane%3B Manganese%3B Membrane%3B Metal-binding%3B Secreted%3B Transmembrane%3B Transmembrane helix%3B Belongs to the LTA synthase family%3B KEGG: lrh:LGG_00830 lipoteichoic acid synthase gene gene2072 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02073 S100141_02074 S100141_02074 S100141_02074 1900932 1901906 - Glucokinase ATP-binding%3B Cytoplasm%3B Glycolysis%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the ROK (NagC/XylR) family%3B KEGG: bli:BL01581 glucokinase gene gene2073 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02074 S100141_02075 S100141_02075 S100141_02075 1901931 1902128 - uncharacterized protein gene gene2074 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02075 S100141_02076 S100141_02076 S100141_02076 1902230 1903684 - Stage V sporulation protein AF Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Belongs to the GerABKA family gene gene2075 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02076 S100141_02077 S100141_02077 gluP gluP 1903761 1905299 - Rhomboid protease Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Repeat%3B Serine protease%3B TPR repeat%3B Transmembrane%3B Transmembrane helix%3B Rhomboid-type serine protease that catalyzes intramembrane proteolysis. Important for normal cell division and sporulation. May act as a glucose exporter%3B Belongs to the peptidase S54 family%3B Contains 2 TPR repeats%3B KEGG: bli:BL03719 rhomboid protease GluP gene gene2076 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02077 S100141_02078 S100141_02078 S100141_02078 1905395 1905568 - uncharacterized protein gene gene2077 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02078 S100141_02079 S100141_02079 S100141_02079 1905618 1906145 - 5-formyltetrahydrofolate cyclo-ligase ATP-binding%3B Nucleotide-binding%3B Belongs to the 5-formyltetrahydrofolate cyclo-ligase family%3B KEGG: bli:BL03718 5-formyltetrahydrofolate cyclo-ligase gene gene2078 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02079 S100141_02080 S100141_02080 S100141_02080 1906240 1906389 - 50S ribosomal protein L33 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L33P family gene gene2079 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02080 S100141_02081 S100141_02081 S100141_02081 1906493 1907605 - Glycogen(starch) synthase Glycosyltransferase%3B Transferase%3B Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: dca:Desca_1720 glycogen(starch) synthase gene gene2080 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02081 S100141_02082 S100141_02082 S100141_02082 1907602 1908099 - uncharacterized protein gene gene2081 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02082 S100141_02083 S100141_02083 S100141_02083 1908260 1908625 + uncharacterized protein Cell membrane%3B Coiled coil%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B overlaps another CDS with the same product name gene gene2082 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02083 S100141_02084 S100141_02084 S100141_02084 1908622 1909101 + uncharacterized protein Signal%3B overlaps another CDS with the same product name gene gene2083 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02084 S100141_02085 S100141_02085 pstB pstB 1909193 1909972 - Phosphate-transporting ATPase ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Phosphate transport%3B Transport%3B Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphate importer (TC 3. A. 1. 7) family%3B Contains 1 ABC transporter domain%3B KEGG: bli:BL03715 phosphate transport system ATP-binding protein gene gene2084 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02085 S100141_02086 S100141_02086 S100141_02086 1909985 1910812 - Phosphate-transporting ATPase ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Phosphate transport%3B Transport%3B Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphate importer (TC 3. A. 1. 7) family%3B Contains 1 ABC transporter domain%3B KEGG: bli:BL03714 phosphate transport system ATP-binding protein gene gene2085 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02086 S100141_02087 S100141_02087 S100141_02087 1910832 1911719 - putative ABC transporter permease protein YqgI Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system YqgGHIJK. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2086 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02087 S100141_02088 S100141_02088 S100141_02088 1911719 1912648 - putative ABC transporter permease protein YqgH Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system YqgGHIJK. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2087 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02088 S100141_02089 S100141_02089 S100141_02089 1912722 1913639 - Phosphate-binding protein PstS Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Phosphate transport%3B Signal%3B Transport%3B Part of the ABC transporter complex PstSACB involved in phosphate import%3B Belongs to the PstS family gene gene2088 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02089 S100141_02090 S100141_02090 S100141_02090 1913832 1915952 - uncharacterized protein Cell membrane%3B Cell shape%3B Membrane%3B Peptidoglycan synthesis%3B Transmembrane%3B Transmembrane helix%3B Belongs to the transpeptidase family%3B KEGG: seq:SZO_13590 penicillin-binding protein 2B%3B Aminoacyltransferases gene gene2089 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02090 S100141_02091 S100141_02091 S100141_02091 1916054 1917340 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2090 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02091 S100141_02092 S100141_02092 S100141_02092 1917520 1918128 - Superoxide dismutase Iron%3B Manganese%3B Metal-binding%3B Oxidoreductase%3B Stress response%3B Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems%3B Belongs to the iron/manganese superoxide dismutase family%3B KEGG: bva:BVAF_021 superoxide dismutase%2C Fe-Mn family gene gene2091 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02092 S100141_02093 S100141_02093 S100141_02093 1918313 1918795 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2092 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02093 S100141_02094 S100141_02094 S100141_02094 1918953 1919711 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2093 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02094 S100141_02095 S100141_02095 S100141_02095 1919796 1920101 + uncharacterized protein Cell wall%3B Membrane%3B Secreted%3B Transmembrane%3B Transmembrane helix%3B Contains 1 LysM repeat gene gene2094 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02095 S100141_02096 S100141_02096 gcpE gcpE 1920214 1921326 + (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin) 4Fe-4S%3B Iron%3B Iron-sulfur%3B Isoprene biosynthesis%3B Metal-binding%3B Oxidoreductase%3B Converts 2C-methyl-D-erythritol 2%2C4-cyclodiphosphate (ME-2%2C4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate%3B Belongs to the IspG family%3B KEGG: bsu:BSU25070 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase gene gene2095 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02096 S100141_02097 S100141_02097 S100141_02097 1921366 1921737 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2096 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02097 S100141_02098 S100141_02098 S100141_02098 1921857 1922459 + Putative nucleotidase YqfW Hydrolase%3B Belongs to the 5'(3')-deoxyribonucleotidase family gene gene2097 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02098 S100141_02099 S100141_02099 S100141_02099 1922530 1922961 - Zinc-specific metallo-regulatory protein Cytoplasm%3B DNA-binding%3B Metal-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Zinc%3B Acts as a negative controlling element%2C employing Zn(2+) as a cofactor to bind the operator of the repressed genes. Required for the zinc-specific repression of two operons implicated in zinc uptake%2C yciC and ycdHIyceA. Also represses the expression of rpmE2%2C the gene for ribosomal protein L31B%2C which is expressed only after the end of exponential growth%3B Belongs to the Fur family gene gene2098 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02099 S100141_02100 S100141_02100 S100141_02100 1922939 1923799 - 29 kDa membrane protein in psaA 5'region Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the ABC-3 integral membrane protein family gene gene2099 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02100 S100141_02101 S100141_02101 S100141_02101 1923799 1924584 - Spermidine/putrescine import ATP-binding protein PotA ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3. A. 1. 11. 1) family%3B Contains 1 ABC transporter domain gene gene2100 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02101 S100141_02102 S100141_02102 S100141_02102 1924719 1925603 - UPF0750 membrane protein YqfU Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0750 family gene gene2101 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02102 S100141_02103 S100141_02103 S100141_02103 1925727 1925987 + uncharacterized protein gene gene2102 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02103 S100141_02104 S100141_02104 S100141_02104 1926015 1926908 - Deoxyribonuclease IV DNA damage%3B DNA repair%3B Endonuclease%3B Hydrolase%3B Metal-binding%3B Nuclease%3B Zinc%3B Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin%3B Belongs to the AP endonuclease 2 family%3B KEGG: bsu:BSU25130 deoxyribonuclease IV gene gene2103 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02104 S100141_02105 S100141_02105 cshB cshB 1926920 1928239 - RNA helicase ATP-binding%3B Cytoplasm%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Ribosome biogenesis%3B RNA-binding%3B Stress response%3B DEAD-box RNA helicase that plays a role in 70S ribosome assembly. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures%3B Belongs to the DEAD box helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bsu:BSU25140 ATP-dependent RNA helicase CshB gene gene2104 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02105 S100141_02106 S100141_02106 S100141_02106 1928496 1929143 + uncharacterized protein gene gene2105 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02106 S100141_02107 S100141_02107 ispH ispH 1929264 1930208 + 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3Fe-4S%3B Iron%3B Iron-sulfur%3B Isoprene biosynthesis%3B Metal-binding%3B NADP%3B Oxidoreductase%3B Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP)%3B Belongs to the IspH family%3B KEGG: bsu:BSU25160 4-hydroxy-3-methylbut-2-enyl diphosphate reductase gene gene2106 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02107 S100141_02108 S100141_02108 S100141_02108 1930236 1931357 - GTP cyclohydrolase 1 type 2 like protein Metal-binding%3B Belongs to the GTP cyclohydrolase I type 2/NIF3 family gene gene2107 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02108 S100141_02109 S100141_02109 trmK trmK 1931354 1932067 - tRNA (adenine(22)-N(1))-methyltransferase Cytoplasm%3B Methyltransferase%3B Phosphoprotein%3B S-adenosyl-L-methionine%3B Transferase%3B tRNA processing%3B Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 22 (m1A22) in tRNA%3B Belongs to the TrmK family%3B KEGG: bsq:B657_25180 tRNA (adenine22-N1)-methyltransferase gene gene2108 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02109 S100141_02110 S100141_02110 S100141_02110 1932157 1932441 - Deoxyribonuclease V Cytoplasm%3B DNA damage%3B DNA repair%3B Endonuclease%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nuclease%3B DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA%3B Belongs to the endonuclease V family%3B KEGG: bst:GYO_3975 deoxyribonuclease V%3B overlaps another CDS with the same product name gene gene2109 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02110 S100141_02111 S100141_02111 S100141_02111 1932438 1932881 - Deoxyribonuclease V Cytoplasm%3B DNA damage%3B DNA repair%3B Endonuclease%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nuclease%3B DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA%3B Belongs to the endonuclease V family%3B KEGG: blh:BaLi_c27850 deoxyribonuclease V%3B overlaps another CDS with the same product name gene gene2110 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02111 S100141_02112 S100141_02112 S100141_02112 1933095 1933319 - hypothetical protein gene gene2111 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02112 S100141_02113 S100141_02113 S100141_02113 1933542 1934192 - hypothetical protein gene gene2112 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02113 S100141_02114 S100141_02114 S100141_02114 1934470 1934874 - hypothetical protein gene gene2113 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02114 S100141_02115 S100141_02115 S100141_02115 1934955 1935293 - hypothetical protein gene gene2114 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02115 S100141_02116 S100141_02116 S100141_02116 1935398 1935907 - hypothetical protein gene gene2115 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02116 S100141_02117 S100141_02117 S100141_02117 1936140 1936475 - hypothetical protein gene gene2116 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02117 S100141_02118 S100141_02118 S100141_02118 1936451 1936642 - hypothetical protein gene gene2117 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02118 S100141_02119 S100141_02119 S100141_02119 1936794 1937303 - hypothetical protein gene gene2118 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02119 S100141_02120 S100141_02120 S100141_02120 1937320 1939329 - Putative ribonuclease YwqJ Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Probable toxic component of a toxin-antitoxin (TA) module. The C-terminus may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YwqK%2C but not by antitoxins specific to other toxins with the LXG domain (By similarity)%3B Contains 1 LXG domain gene gene2119 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02120 S100141_02121 S100141_02121 S100141_02121 1939354 1939617 - uncharacterized protein Coiled coil%3B overlaps another CDS with the same product name gene gene2120 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02121 S100141_02122 S100141_02122 S100141_02122 1939617 1940051 - uncharacterized protein Coiled coil%3B overlaps another CDS with the same product name gene gene2121 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02122 S100141_02123 S100141_02123 S100141_02123 1940421 1940780 - Cytochrome c-550 Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Transmembrane%3B Transmembrane helix%3B Transport. gene gene2122 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02123 S100141_02124 S100141_02124 S100141_02124 1941137 1942258 - RNA polymerase sigma factor SigA Cytoplasm%3B DNA-binding%3B Sigma factor%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth%3B Belongs to the sigma-70 factor family. RpoD/SigA subfamily gene gene2123 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02124 S100141_02125 S100141_02125 dnaG dnaG 1942465 1944288 - DNA primase DNA replication%3B DNA-binding%3B DNA-directed RNA polymerase%3B Magnesium%3B Metal-binding%3B Nucleotidyltransferase%3B Primosome%3B Transcription%3B Transferase%3B Zinc%3B Zinc-finger%3B RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication%3B Belongs to the DnaG primase family%3B Contains 1 Toprim domain%3B KEGG: noc:Noc_0044 DNA primase%3B Nucleotidyltransferases gene gene2124 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02125 S100141_02126 S100141_02126 S100141_02126 1944321 1944812 - UPF0178 protein Belongs to the UPF0178 family gene gene2125 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02126 S100141_02127 S100141_02127 S100141_02127 1945077 1945889 - Putative pyruvate%2C phosphate dikinase regulatory protein Kinase%3B Nucleotide-binding%3B Serine/threonine-protein kinase%3B Transferase%3B Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate%2C phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation%3B Belongs to the pyruvate%2C phosphate/water dikinase regulatory protein family. PDRP subfamily gene gene2126 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02127 S100141_02128 S100141_02128 S100141_02128 1945915 1946514 - Transcriptional repressor CcpN DNA-binding%3B Repeat%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcription repressor that binds to the promoter of gapB and pckA genes%2C preventing their expression. Acts as a regulator for catabolite repression of gluconeogenic genes%3B Contains 2 CBS domains%3B Contains 1 HTH deoR-type DNA-binding domain gene gene2127 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02128 S100141_02129 S100141_02129 glyS glyS 1946751 1948790 - Glycine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: pin:Ping_3726 glycyl-tRNA synthetase beta chain%3B overlaps another CDS with the same product name gene gene2128 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02129 S100141_02130 S100141_02130 glyQ glyQ 1948783 1949670 - Glycine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: wbr:WGLp593 glycyl-tRNA synthetase alpha chain%3B overlaps another CDS with the same product name gene gene2129 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02130 S100141_02131 S100141_02131 S100141_02131 1950002 1950772 - DNA repair protein RecO DNA damage%3B DNA recombination%3B DNA repair%3B Involved in DNA repair and RecF pathway recombination%3B Belongs to the RecO family gene gene2130 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02131 S100141_02132 S100141_02132 S100141_02132 1950810 1950953 - uncharacterized protein gene gene2131 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02132 S100141_02133 S100141_02133 S100141_02133 1951115 1952020 - GTPase Era Cell membrane%3B Cytoplasm%3B GTP-binding%3B Membrane%3B Nucleotide-binding%3B Ribosome biogenesis%3B RNA-binding%3B rRNA-binding%3B An essential GTPase that binds both GDP and GTP%2C with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity). Binds both GDP and GTP. Complements an E. coli era disruption mutant%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. Era GTPase family%3B Contains 1 Era-type G (guanine nucleotide-binding) domain%3B Contains 1 KH type-2 domain gene gene2132 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02133 S100141_02134 S100141_02134 S100141_02134 1952001 1952411 - Cytidine deaminase Hydrolase%3B Metal-binding%3B Zinc%3B This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. Belongs to the cytidine and deoxycytidylate deaminase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: bli:BL03673 cytidine deaminase gene gene2133 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02134 S100141_02135 S100141_02135 S100141_02135 1952543 1952923 - Undecaprenol kinase ATP-binding%3B Cell membrane%3B Kinase%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Nucleotide-binding%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Recycling of diacylglycerol produced during the turnover of membrane phospholipid%3B Belongs to the bacterial diacylglycerol kinase family%3B KEGG: bli:BL03672 undecaprenol kinase gene gene2134 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02135 S100141_02136 S100141_02136 S100141_02136 1952901 1953377 - Endoribonuclease YbeY Cytoplasm%3B Endonuclease%3B Hydrolase%3B Metal-binding%3B Nuclease%3B Ribosome biogenesis%3B rRNA processing%3B Zinc%3B Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA%3B Belongs to the endoribonuclease YbeY family gene gene2135 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02136 S100141_02137 S100141_02137 S100141_02137 1953374 1955524 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2136 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02137 S100141_02138 S100141_02138 S100141_02138 1955593 1956552 - PhoH-like protein ATP-binding%3B Cytoplasm%3B Nucleotide-binding%3B Belongs to the PhoH family gene gene2137 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02138 S100141_02139 S100141_02139 S100141_02139 1956549 1957745 - uncharacterized protein Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B To B. megaterium SpoIV gene gene2138 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02139 S100141_02140 S100141_02140 S100141_02140 1957763 1958044 - uncharacterized protein gene gene2139 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02140 S100141_02141 S100141_02141 S100141_02141 1958100 1958549 - uncharacterized protein Cell membrane%3B Coiled coil%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2140 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02141 S100141_02142 S100141_02142 S100141_02142 1958579 1959571 - UPF0365 protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0365 family gene gene2141 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02142 S100141_02143 S100141_02143 S100141_02143 1959595 1960914 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2142 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02143 S100141_02144 S100141_02144 S100141_02144 1961059 1961505 - uncharacterized protein gene gene2143 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02144 S100141_02145 S100141_02145 S100141_02145 1961520 1961693 - 30S ribosomal protein S21 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein S21P family gene gene2144 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02145 S100141_02146 S100141_02146 S100141_02146 1961879 1962814 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B To E. coli YjbB gene gene2145 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02146 S100141_02147 S100141_02147 deoC deoC 1962834 1963505 - Deoxyribose-phosphate aldolase Cytoplasm%3B Lyase%3B Schiff base%3B Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate%3B Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily%3B KEGG: bli:BL02102 deoxyribose-phosphate aldolase gene gene2146 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02147 S100141_02148 S100141_02148 mtaB mtaB 1963596 1964951 - tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase 4Fe-4S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B S-adenosyl-L-methionine%3B Transferase%3B tRNA processing%3B Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A)%2C leading to the formation of 2- methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine%3B Belongs to the methylthiotransferase family. MtaB subfamily%3B Contains 1 MTTase N-terminal domain%3B Contains 1 TRAM domain%3B KEGG: bsu:BSU25430 threonylcarbamoyladenosine tRNA methylthiotransferase MtaB gene gene2147 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02148 S100141_02149 S100141_02149 rsmE rsmE 1964954 1965721 - 16S rRNA (uracil(1498)-N(3))-methyltransferase Cytoplasm%3B Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)%3B Belongs to the RNA methyltransferase RsmE family%3B KEGG: bli:BL02100 16S rRNA (uracil1498-N3)-methyltransferase gene gene2148 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02149 S100141_02150 S100141_02150 prmA prmA 1965745 1966680 - Ribosomal protein L11 methyltransferase Cytoplasm%3B Methyltransferase%3B Transferase%3B Methylates ribosomal protein L11%3B Belongs to the methyltransferase superfamily. PrmA family%3B KEGG: bli:BL02099 ribosomal protein L11 methyltransferase%3B Methyltransferases gene gene2149 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02150 S100141_02151 S100141_02151 S100141_02151 1966704 1967831 - Chaperone protein DnaJ Chaperone%3B Cytoplasm%3B DNA replication%3B Metal-binding%3B Repeat%3B Stress response%3B Zinc%3B Zinc-finger%3B Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins%2C also in an autonomous%2C DnaK-independent fashion. Unfolded proteins bind initially to Dna%3B upon interaction with the DnaJ-bound protein%2C DnaK hydrolyzes its bound ATP%2C resulting in the formation of a stable complex. GrpE releases ADP from Dna%3B ATP binding to DnaK triggers the release of the substrate protein%2C thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ%2C DnaK and GrpE are required for fully efficient folding. Also involved%2C together with DnaK and GrpE%2C in the DNA replication of plasmids through activation of initiation proteins%3B Belongs to the DnaJ family%3B Contains 1 CR-type zinc finger%3B Contains 1 J domain gene gene2150 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02151 S100141_02152 S100141_02152 S100141_02152 1968014 1969852 - Chaperone protein DnaK ATP-binding%3B Chaperone%3B Nucleotide-binding%3B Phosphoprotein%3B Stress response%3B Acts as a chaperone%3B Belongs to the heat shock protein 70 family gene gene2151 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02152 S100141_02153 S100141_02153 S100141_02153 1969876 1970460 - Protein GrpE Chaperone%3B Cytoplasm%3B Stress response%3B Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins%2C in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to Dna%3B upon interaction with the DnaJ-bound protein%2C DnaK hydrolyzes its bound ATP%2C resulting in the formation of a stable complex. GrpE releases ADP from Dna%3B ATP binding to DnaK triggers the release of the substrate protein%2C thus completing the reaction cycle. Several rounds of ATP- dependent interactions between DnaJ%2C DnaK and GrpE are required for fully efficient folding%3B Belongs to the GrpE family gene gene2152 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02153 S100141_02154 S100141_02154 S100141_02154 1970539 1971570 - Heat-inducible transcription repressor HrcA Repressor%3B Stress response%3B Transcription%3B Transcription regulation%3B Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons%3B Belongs to the HrcA family gene gene2153 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02154 S100141_02155 S100141_02155 S100141_02155 1971651 1972790 - Coproporphyrinogen dehydrogenase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase%3B Porphyrin biosynthesis%3B S-adenosyl-L-methionine%3B Involved in the biosynthesis of porphyrin-containing compound%3B Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemN-like subfamily%3B KEGG: bli:BL02093 oxygen-independent coproporphyrinogen III oxidase gene gene2154 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02155 S100141_02156 S100141_02156 S100141_02156 1972850 1974688 - Elongation factor Cell membrane%3B GTP-binding%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Protein biosynthesis%3B Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction%2C by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex%2C thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene2155 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02156 S100141_02157 S100141_02157 S100141_02157 1974834 1975157 - uncharacterized protein gene gene2156 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02157 S100141_02158 S100141_02158 S100141_02158 1975173 1976378 - Stage II sporulation protein Sporulation. gene gene2157 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02158 S100141_02159 S100141_02159 S100141_02159 1976497 1977603 - GPR endopeptidase Hydrolase%3B Protease%3B Zymogen%3B Initiates the rapid degradation of small%2C acid-soluble proteins during spore germination%3B Belongs to the peptidase A25 family%3B KEGG: bli:BL02089 spore protease gene gene2158 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02159 S100141_02160 S100141_02160 S100141_02160 1977808 1978074 + 30S ribosomal protein S20 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Binds directly to 16S ribosomal RNA%3B Belongs to the ribosomal protein S20P family gene gene2159 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02160 S100141_02161 S100141_02161 holA holA 1978136 1979200 - DNA-directed DNA polymerase KEGG: bld:BLi02748 DNA polymerase III subunit delta gene gene2160 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02161 S100141_02162 S100141_02162 S100141_02162 1979409 1979540 + putative membrane protein YqzM Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2161 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02162 S100141_02163 S100141_02163 S100141_02163 1979565 1981952 - ComE operon protein Cell membrane%3B Competence%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The comE operon is required for the binding and uptake of transforming DNA. ComEC is required for internalization but is dispensable for DNA binding. To H. influenzae REC2%2C N. gonorrhoeae ComA and E. coli YcaI gene gene2162 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02163 S100141_02164 S100141_02164 S100141_02164 1981956 1982525 - dCMP deaminase Hydrolase%3B Metal-binding%3B Zinc%3B Dispensable for transformability. Belongs to the cytidine and deoxycytidylate deaminase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: bsu:BSU25580 dCMP deaminase gene gene2163 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02164 S100141_02165 S100141_02165 S100141_02165 1982594 1983223 - ComE operon protein Cell membrane%3B Competence%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Needed for both DNA binding and transport. It is absolutely required for the uptake of transforming DNA but not for binding. Its role in binding may be indirect. Contains 2 HhH domains gene gene2164 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02165 S100141_02166 S100141_02166 S100141_02166 1983307 1984128 + ComE operon protein Dispensable for transformability. Not known if it can act as a pyrroline-5-carboxylate reductase. Belongs to the pyrroline-5-carboxylate reductase family gene gene2165 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02166 S100141_02167 S100141_02167 ubiG ubiG 1984198 1984953 - 2-polyprenyl-6-hydroxyphenol methylase Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B May be a S-adenosyl-L-methionine (SAM)-dependent methyltransferase. Belongs to the methyltransferase superfamily%3B KEGG: fil:BN1229_v1_1253 2-polyprenyl-6-hydroxyphenyl methylase / 3-demethylubiquinone-9 3-methyltransferase gene gene2166 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02167 S100141_02168 S100141_02168 S100141_02168 1984950 1985306 - Ribosomal silencing factor RsfS Cytoplasm%3B Repressor%3B Translation regulation%3B Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN)%2C blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes%2C thus repressing translation%3B Belongs to the Iojap/RsfS family gene gene2167 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02168 S100141_02169 S100141_02169 S100141_02169 1985320 1985883 - Nicotinate-nucleotide adenylyltransferase Contains 1 HD domain%3B KEGG: ccel:CCDG5_0474 nicotinate-nucleotide adenylyltransferase%3B overlaps another CDS with the same product name gene gene2168 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02169 S100141_02170 S100141_02170 S100141_02170 1985873 1986442 - Nicotinate-nucleotide adenylyltransferase ATP-binding%3B NAD%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Pyridine nucleotide biosynthesis%3B Transferase%3B Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)%3B Belongs to the NadD family%3B KEGG: nma:NMA0416 nicotinate-nucleotide adenylyltransferase%3B overlaps another CDS with the same product name gene gene2169 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02170 S100141_02171 S100141_02171 S100141_02171 1986461 1986751 - putative RNA-binding protein YqeI RNA-binding%3B Contains 1 CRM domain gene gene2170 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02171 S100141_02172 S100141_02172 aroE aroE 1986745 1987581 - Shikimate dehydrogenase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B NADP%3B Oxidoreductase%3B Involved in the biosynthesis of the chorismate%2C which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)%3B Belongs to the shikimate dehydrogenase family%3B KEGG: bli:BL02079 shikimate dehydrogenase gene gene2171 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02172 S100141_02173 S100141_02173 S100141_02173 1987601 1988701 - uncharacterized protein GTP-binding%3B Nucleotide-binding%3B Binds GTP and GDP. Belongs to the TRAFAC class YlqF/YawG GTPase family%3B Contains 1 CP-type G (guanine nucleotide-binding) domain gene gene2172 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02173 S100141_02174 S100141_02174 S100141_02174 1988705 1989223 - uncharacterized protein gene gene2173 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02174 S100141_02175 S100141_02175 S100141_02175 1989849 1990004 - hypothetical protein gene gene2174 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02175 S100141_02176 S100141_02176 S100141_02176 1990082 1990813 - putative lipoprotein YqeF Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal. gene gene2175 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02176 S100141_02177 S100141_02177 S100141_02177 1990957 1991718 - putative N-acetyltransferase YdfB Acyltransferase%3B Transferase%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK4362 null%3B Transferring groups other than amino-acyl groups gene gene2176 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02177 S100141_02178 S100141_02178 S100141_02178 1991750 1992124 - uncharacterized protein gene gene2177 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02178 S100141_02179 S100141_02179 S100141_02179 1992428 1995367 + Formate dehydrogenase 2Fe-2S%3B 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Molybdenum%3B NAD%3B Oxidoreductase%3B Repeat%3B In the C-terminal sectio%3B belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 2Fe-2S ferredoxin-type domain%3B Contains 2 4Fe-4S ferredoxin-type domains%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: bli:BL02109 formate dehydrogenase major subunit gene gene2178 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02179 S100141_02180 S100141_02180 S100141_02180 1995389 1995868 + uncharacterized protein To A. fulgidus AF1717 gene gene2179 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02180 S100141_02181 S100141_02181 S100141_02181 1995944 1996180 - hypothetical protein gene gene2180 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02181 S100141_02182 S100141_02182 S100141_02182 1996415 1997140 + RNA polymerase sigma-K factor DNA-binding%3B Sigma factor%3B Sporulation%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the mother cell. Belongs to the sigma-70 factor family gene gene2181 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02182 S100141_02183 S100141_02183 S100141_02183 1997435 1998385 - hypothetical protein gene gene2182 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02183 S100141_02184 S100141_02184 S100141_02184 1999057 2000862 - Subtilin transport ATP-binding protein SpaT ATP-binding%3B Bacteriocin transport%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably implicated in the export process of the lantibiotic subtilin. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene2183 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02184 S100141_02185 S100141_02185 S100141_02185 2000913 2001083 - hypothetical protein gene gene2184 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02185 S100141_02186 S100141_02186 S100141_02186 2001114 2001659 - hypothetical protein gene gene2185 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02186 S100141_02187 S100141_02187 S100141_02187 2001656 2002186 - hypothetical protein gene gene2186 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02187 S100141_02188 S100141_02188 S100141_02188 2002376 2003533 + Stage II sporulation protein Sporulation. gene gene2187 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02188 S100141_02189 S100141_02189 S100141_02189 2003548 2003712 + hypothetical protein gene gene2188 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02189 S100141_02190 S100141_02190 S100141_02190 2003956 2004177 - hypothetical protein gene gene2189 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02190 S100141_02191 S100141_02191 S100141_02191 2004499 2004813 + RNA polymerase sigma-28 factor DNA-binding%3B Sigma factor%3B Sporulation%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor directs the transcription of crystal protein genes%2C a sporulation-regulated event (By similarity)%3B Belongs to the sigma-70 factor family gene gene2190 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02191 S100141_02192 S100141_02192 S100141_02192 2005266 2007116 + hypothetical protein gene gene2191 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02192 S100141_02193 S100141_02193 S100141_02193 2007312 2007995 - hypothetical protein gene gene2192 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02193 S100141_02194 S100141_02194 S100141_02194 2008168 2010678 - hypothetical protein gene gene2193 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02194 S100141_02195 S100141_02195 S100141_02195 2011027 2011341 + RNA polymerase sigma-28 factor DNA-binding%3B Sigma factor%3B Sporulation%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor directs the transcription of crystal protein genes%2C a sporulation-regulated event (By similarity)%3B Belongs to the sigma-70 factor family gene gene2194 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02195 S100141_02196 S100141_02196 S100141_02196 2011720 2012286 - hypothetical protein gene gene2195 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02196 S100141_02197 S100141_02197 S100141_02197 2013016 2013696 - Methionine import ATP-binding protein MetN Amino-acid transport%3B ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Methionine importer (TC 3. A. 1. 24) family%3B Contains 1 ABC transporter domain gene gene2196 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02197 S100141_02198 S100141_02198 S100141_02198 2013693 2014796 - Putative hemin transport system permease protein HrtB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the ABC-4 integral membrane protein family. HrtB subfamily gene gene2197 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02198 S100141_02199 S100141_02199 S100141_02199 2014899 2016278 - Heme sensor protein HssS ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Virulence%3B Member of the two-component regulatory system HssS/HssR involved in intracellular heme homeostasis and tempering of staphylococcal virulence. HssS functions as a heme sensor histidine kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to an aspartate residue of HssR. HssR/HssS activates the expression of hrtAB%2C an efflux pump%2C in response to extracellular heme%2C hemin%2C hemoglobin or blood (By similarity)%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: lwe:lwe2532 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene2198 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02199 S100141_02200 S100141_02200 S100141_02200 2016275 2016949 - Response regulator ArlR Activator%3B Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Repressor%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Virulence%3B Member of the two-component regulatory system ArlS/ArlR involved in the regulation of adhesion%2C autolysis%2C multidrug resistance and virulence%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2199 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02200 S100141_02201 S100141_02201 S100141_02201 2018267 2018491 - Spore coat protein Sporulation. gene gene2200 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02201 S100141_02202 S100141_02202 S100141_02202 2019012 2019143 - hypothetical protein gene gene2201 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02202 S100141_02203 S100141_02203 S100141_02203 2019580 2019894 + RNA polymerase sigma-28 factor DNA-binding%3B Sigma factor%3B Sporulation%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor directs the transcription of crystal protein genes%2C a sporulation-regulated event (By similarity)%3B Belongs to the sigma-70 factor family gene gene2202 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02203 S100141_02204 S100141_02204 S100141_02204 2019946 2020476 - hypothetical protein gene gene2203 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02204 S100141_02205 S100141_02205 S100141_02205 2020559 2021083 - putative N-acetyltransferase YuaI Acyltransferase%3B Transferase%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: tth:TTC0848 null%3B Transferring groups other than amino-acyl groups gene gene2204 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02205 S100141_02206 S100141_02206 S100141_02206 2022334 2022708 - UPF0715 membrane protein YwlA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0715 family gene gene2205 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02206 S100141_02207 S100141_02207 S100141_02207 2022764 2024113 + hypothetical protein gene gene2206 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02207 S100141_02208 S100141_02208 S100141_02208 2024676 2025986 - hypothetical protein gene gene2207 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02208 S100141_02209 S100141_02209 S100141_02209 2026648 2027388 - hypothetical protein gene gene2208 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02209 S100141_02210 S100141_02210 S100141_02210 2027647 2029080 - Hydroxyacylglutathione hydrolase Belongs to the UPF0033 family%3B Contains 1 rhodanese domain%3B KEGG: bst:GYO_2875 hydroxyacylglutathione hydrolase gene gene2209 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02210 S100141_02211 S100141_02211 S100141_02211 2029153 2030352 - Sulfide:quinone oxidoreductase%2C mitochondrial FAD%3B Flavoprotein%3B Mitochondrion%3B Oxidoreductase%3B Quinone%3B Transit peptide%3B Catalyzes the oxidation of hydrogen sulfide%2C with the help of a quinone%3B Belongs to the SQRD family%3B KEGG: bst:GYO_2876 sulfide:quinone oxidoreductase%3B With a quinone or similar compound as acceptor gene gene2210 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02211 S100141_02212 S100141_02212 S100141_02212 2030513 2031157 - Chemotaxis response regulator protein-glutamate methylesterase Chemotaxis%3B Cytoplasm%3B Hydrolase%3B Phosphoprotein%3B Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene2211 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02212 S100141_02213 S100141_02213 nreB nreB 2031132 2032211 - Histidine kinase 4Fe-4S%3B ATP-binding%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Kinase%3B Metal-binding%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Two-component regulatory system%3B Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated%2C in the absence of oxygen%2C probably at the conserved histidine residue%2C and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons%2C as well as the putative nitrate transporter gene narT%3B Contains 1 histidine kinase domain%3B KEGG: bbe:BBR47_03990 two-component system%2C NarL family%2C sensor histidine kinase NreB gene gene2212 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02213 S100141_02214 S100141_02214 S100141_02214 2032233 2032568 - Thioredoxin-like protein YdfQ Disulfide bond%3B Redox-active center%3B Contains 1 thioredoxin domain gene gene2213 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02214 S100141_02215 S100141_02215 S100141_02215 2032590 2033372 - UPF0721 transmembrane protein YrkJ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0721 family gene gene2214 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02215 S100141_02216 S100141_02216 tusA tusA 2033427 2033654 - UPF0033 protein YrkI Belongs to the UPF0033 family%3B KEGG: afe:Lferr_2187 tRNA 2-thiouridine synthesizing protein A%3B Sulfurtransferases gene gene2215 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02216 S100141_02217 S100141_02217 S100141_02217 2033682 2034812 - Hydroxyacylglutathione hydrolase Contains 1 rhodanese domain%3B KEGG: mba:Mbar_A2729 hydroxyacylglutathione hydrolase gene gene2216 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02217 S100141_02218 S100141_02218 S100141_02218 2034913 2035485 - UPF0033 protein YrkI Belongs to the UPF0033 family%3B KEGG: afe:Lferr_2187 tRNA 2-thiouridine synthesizing protein A%3B Sulfurtransferases gene gene2217 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02218 S100141_02219 S100141_02219 S100141_02219 2035592 2036074 - uncharacterized protein KEGG: gca:Galf_0318 tRNA 2-thiouridine synthesizing protein A%3B Sulfurtransferases gene gene2218 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02219 S100141_02220 S100141_02220 S100141_02220 2036237 2036497 - Copper-sensing transcriptional repressor CsoR Copper%3B Cytoplasm%3B DNA-binding%3B Metal-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Copper-sensitive repressor that has a key role in copper homeostasis. Negatively regulates expression of the copZA operon and of ycnJ. In the absence of copper ions%2C binds with high affinity to the copZA promoter and represses the transcription. In the presence of copper ions%2C CsoR binds Cu(1+)%2C which significantly decreases its DNA binding affinity and leads to the transcription of the genes%3B Belongs to the CsoR family gene gene2219 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02220 S100141_02221 S100141_02221 S100141_02221 2036972 2037568 - hypothetical protein gene gene2220 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02221 S100141_02222 S100141_02222 S100141_02222 2037613 2038320 - uncharacterized protein gene gene2221 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02222 S100141_02223 S100141_02223 S100141_02223 2039688 2040530 - hypothetical protein gene gene2222 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02223 S100141_02224 S100141_02224 S100141_02224 2041039 2041284 - Putative membrane protein insertion efficiency factor Cell membrane%3B Membrane%3B Could be involved in insertion of integral membrane proteins into the membrane%3B Belongs to the UPF0161 family gene gene2223 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02224 S100141_02225 S100141_02225 S100141_02225 2041851 2041955 - hypothetical protein gene gene2224 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02225 S100141_02226 S100141_02226 hxlB hxlB 2042116 2042673 - 6-phospho-3-hexuloisomerase Carbohydrate metabolism%3B Isomerase%3B Catalyzes the isomerization between 3-hexulose 6- phosphate and fructose 6-phosphate%3B Belongs to the SIS family. PHI subfamily%3B Contains 1 SIS domain%3B KEGG: blh:BaLi_c28990 6-phospho-3-hexuloisomerase gene gene2225 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02226 S100141_02227 S100141_02227 hxlA hxlA 2042670 2043302 - 3-hexulose-6-phosphate synthase Carbohydrate metabolism%3B Lyase%3B One-carbon metabolism%3B Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate%3B Belongs to the HPS/KGPDC family. HPS subfamily%3B KEGG: eum:ECUMN_2963 3-hexulose-6-phosphate synthase gene gene2226 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02227 S100141_02228 S100141_02228 S100141_02228 2043490 2043837 - HTH-type transcriptional activator HxlR Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Positive regulator of hxlAB expression. Contains 1 HTH hxlR-type DNA-binding domain gene gene2227 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02228 S100141_02229 S100141_02229 fad6 fad6 2044131 2045189 + Fatty acid desaturase Cell membrane%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsaturated fatty acids%3B Belongs to the fatty acid desaturase family%3B KEGG: bsu:BSU19180 omega-6 fatty acid desaturase (delta-12 desaturase)%3B With oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water gene gene2228 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02229 S100141_02230 S100141_02230 desK desK 2045310 2046422 + Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system DesR/DesK%2C responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase. Acts as a sensor of the membrane fluidity. Probably activates DesR by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bsr:I33_2153 two-component system%2C NarL family%2C sensor histidine kinase DesK gene gene2229 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02230 S100141_02231 S100141_02231 S100141_02231 2046441 2047040 + Transcriptional regulatory protein DesR Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system DesR/DesK%2C responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase%3B Contains 1 HTH luxR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2230 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02231 S100141_02232 S100141_02232 S100141_02232 2047116 2048165 - Thioredoxin-disulfide reductase FAD%3B Flavoprotein%3B NADP%3B Oxidoreductase%3B Belongs to the ferredoxin--NADP reductase type 2 family%3B KEGG: bli:BL02042 thioredoxin reductase (NADPH) gene gene2231 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02232 S100141_02233 S100141_02233 S100141_02233 2048455 2050077 + Nickel-binding periplasmic protein Nickel%3B Periplasm%3B Signal%3B Transport%3B Involved in a nickel transport system%2C probably represents the nickel binder. Belongs to the bacterial solute-binding protein 5 family gene gene2232 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02233 S100141_02234 S100141_02234 S100141_02234 2050087 2051031 + Putative oligopeptide transport system permease protein oppB2 Cell membrane%3B Membrane%3B Peptide transport%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of a transport system that may be involved in oligopeptide uptake. Probably responsible for the translocation of the substrate across the membrane. Important for S. aureus growth and survival during the infection process (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2233 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02234 S100141_02235 S100141_02235 S100141_02235 2051028 2051861 + Oligopeptide transport system permease protein OppC Cell membrane%3B Competence%3B Membrane%3B Peptide transport%3B Protein transport%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system for oligopeptide%3B probably responsible for the translocation of the substrate across the membrane. Also required for sporulation and competence. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2234 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02235 S100141_02236 S100141_02236 nikD nikD 2051877 2052695 + Nickel-transporting ATPase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Peptide transport%3B Protein transport%3B Transport%3B Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: bli:BL02421 nickel transport system ATP-binding protein gene gene2235 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02236 S100141_02237 S100141_02237 S100141_02237 2052692 2053555 + putative ABC transporter ATP-binding protein YcbN ATP-binding%3B Nucleotide-binding%3B Transport%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene2236 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02237 S100141_02238 S100141_02238 S100141_02238 2053868 2054704 + putative HTH-type transcriptional regulator YdfL DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH merR-type DNA-binding domain gene gene2237 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02238 S100141_02239 S100141_02239 S100141_02239 2054761 2056116 + Multidrug export protein MepA Antibiotic resistance%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Multidrug resistance efflux protein%3B Belongs to the multi antimicrobial extrusion (MATE) (TC 2. A. 66. 1) family. MepA subfamily gene gene2238 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02239 S100141_02240 S100141_02240 S100141_02240 2056430 2057437 + HTH-type transcriptional regulator GadX Activator%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Virulence%3B Positively regulates the expression of about fifteen genes involved in acid resistance such as gadA%2C gadB and gadC. Depending on the conditions (growth phase and medium)%2C can repress gadW (By similarity). Negatively regulates perA expression in acidic conditions and positively regulates it in alkaline conditions%3B Contains 1 HTH araC/xylS-type DNA-binding domain gene gene2239 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02240 S100141_02241 S100141_02241 S100141_02241 2057455 2058249 + 3-oxoacyl-[acyl-carrier-protein] reductase Acetylation%3B Alternative splicing%3B Mitochondrion%3B Nucleus%3B Oxidoreductase%3B Phosphoprotein%3B Polymorphism%3B Transit peptide%3B Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3%2C4-Hexanedione%2C 2%2C3-Heptanedione and 1-Phenyl-1%2C2- propanedione as substrates. No reductase activity is displayed in vitro with steroids%2C retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation%2C leading to p53/TP53 stabilization and increased transcription activity%2C resulting in the accumulation of MDM2 and CDKN1A/p21%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: pao:Pat9b_1844 3-oxoacyl-(acyl-carrier protein) reductase gene gene2240 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02241 S100141_02242 S100141_02242 phoN phoN 2058361 2060151 - Acid phosphatase Hydrolase%3B Periplasm%3B Signal%3B Belongs to the class A bacterial acid phosphatase family%3B KEGG: sty:STY4519 acid phosphatase (class A) gene gene2241 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02242 S100141_02243 S100141_02243 pnbA pnbA 2060425 2061252 - Isoprenylcysteine alpha-carbonyl methylesterase ICME Alternative splicing%3B Endoplasmic reticulum%3B Golgi apparatus%3B Hydrolase%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the demethylation of isoprenylcysteine methylesters. In vitro%2C is specific for N-acetyl-S-farnesyl-L- cysteine methyl ester (AFCme) and has low activity toward N- acetyl-S-geranyl-L-cysteine methyl ester (AGCme). Acts as a positive regulator of ABA signaling. May be involved in the demethylation and inactivation of isoprenylated negative regulators of abscisic acid (ABA) signaling. Carboxyl methylation is a reversible and potentially regulated step in the post- translational modification of prenylated proteins%3B Belongs to the AB hydrolase superfamily. Isoprenylcysteine methylesterase family%3B KEGG: pat:Patl_0510 para-nitrobenzyl esterase%3B Carboxylic ester hydrolases gene gene2242 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02243 S100141_02244 S100141_02244 S100141_02244 2061678 2062913 - Cytochrome P450 Heme%3B Iron%3B Metal-binding%3B Monooxygenase%3B Oxidoreductase%3B Belongs to the cytochrome P450 family%3B KEGG: ban:BA_2627 null%3B Acting on paired donors%2C with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O(2) gene gene2243 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02244 S100141_02245 S100141_02245 S100141_02245 2063311 2064198 - UPF0721 transmembrane protein YtnM Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0721 family gene gene2244 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02245 S100141_02246 S100141_02246 S100141_02246 2064507 2064887 + hypothetical protein gene gene2245 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02246 S100141_02247 S100141_02247 S100141_02247 2065074 2065871 + 3-oxoacyl-[acyl-carrier-protein] reductase Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bld:BLi02826 3-oxoacyl-(acyl-carrier protein) reductase gene gene2246 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02247 S100141_02248 S100141_02248 S100141_02248 2065909 2067942 - Fructan beta-fructosidase Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Secreted%3B Signal%3B Exo-fructosidase that can hydrolyze both levan and inulin%2C leading to the production of free fructose. Is also able to hydrolyze sucrose and to a small extent raffinose%2C but not melezitose%2C stachylose%2C cellobiose%2C maltose%2C and lactose%3B Belongs to the glycosyl hydrolase 32 family%3B KEGG: bsu:BSU27030 fructan beta-fructosidase gene gene2247 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02248 S100141_02249 S100141_02249 S100141_02249 2068063 2068890 - Fructose permease IID component Cell membrane%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in fructose transport. Contains 1 PTS EIID domain gene gene2248 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02249 S100141_02250 S100141_02250 S100141_02250 2068912 2069715 - Fructose permease IIC component Cell membrane%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in fructose transport. Contains 1 PTS EIIC type-4 domain gene gene2249 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02250 S100141_02251 S100141_02251 levE levE 2069734 2070225 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cytoplasm%3B Kinase%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport. LevD and LevE act as negative regulators of the levanase operon. They may be involved in a PTS-mediated phosphorylation of a regulator. Contains 1 PTS EIIB type-4 domain%3B KEGG: kox:KOX_13535 PTS system%2C fructose-specific IIB component%3B overlaps another CDS with the same product name gene gene2250 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02251 S100141_02252 S100141_02252 agaF agaF 2070225 2070662 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cytoplasm%3B Kinase%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport. LevD and LevE act as negative regulators of the levanase operon. They may be involved in a PTS-mediated phosphorylation of a regulator. Contains 1 PTS EIIA type-4 domain%3B KEGG: ece:Z4488 PTS system%2C N-acetylgalactosamine-specific IIA component%3B overlaps another CDS with the same product name gene gene2251 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02252 S100141_02253 S100141_02253 S100141_02253 2070864 2072804 - Transcriptional regulatory protein LevR Activator%3B ATP-binding%3B DNA-binding%3B Kinase%3B Nucleotide-binding%3B Phosphoprotein%3B Repeat%3B Transcription%3B Transcription regulation%3B Transferase%3B Involved in positive regulation of the levanase operon which comprises the levDEFG genes for a fructose PTS system%2C and sacA for levanase. Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains%3B Contains 1 PTS EIIA type-4 domain%3B Contains 1 sigma-54 factor interaction domain gene gene2252 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02253 S100141_02254 S100141_02254 S100141_02254 2072890 2073228 - Transcriptional regulatory protein LevR Activator%3B ATP-binding%3B DNA-binding%3B Kinase%3B Nucleotide-binding%3B Phosphoprotein%3B Repeat%3B Transcription%3B Transcription regulation%3B Transferase%3B Involved in positive regulation of the levanase operon which comprises the levDEFG genes for a fructose PTS system%2C and sacA for levanase. Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains%3B Contains 1 PTS EIIA type-4 domain%3B Contains 1 sigma-54 factor interaction domain gene gene2253 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02254 S100141_02255 S100141_02255 S100141_02255 2073549 2074013 - uncharacterized protein Signal. gene gene2254 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02255 S100141_02256 S100141_02256 S100141_02256 2074134 2074394 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2255 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02256 S100141_02257 S100141_02257 catA catA 2074462 2075112 - Chloramphenicol O-acetyltransferase Acyltransferase%3B Antibiotic resistance%3B Plasmid%3B Transferase%3B This enzyme is an effector of chloramphenicol resistance in bacteria. Belongs to the chloramphenicol acetyltransferase family%3B KEGG: bli:BL03127 chloramphenicol O-acetyltransferase type A gene gene2256 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02257 S100141_02258 S100141_02258 adaB adaB 2075891 2076418 + Methylated-DNA--[protein]-cysteine S-methyltransferase DNA damage%3B DNA repair%3B Methyltransferase%3B Transferase%3B Is involved in the adaptive response to alkylation damage in DNA caused by alkylating agents. Repairs O6- methylguanine residues in alkylated DNA by a direct and irreversible transfer of the methyl group from the base to one of its own cysteine residues%3B Belongs to the MGMT family%3B KEGG: bli:BL00477 methylated-DNA-(protein)-cysteine S-methyltransferase gene gene2257 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02258 S100141_02259 S100141_02259 akr1 akr1 2076452 2077300 - Aldehyde reductase NADP%3B Oxidoreductase%3B Reduces glyoxal and methylglyoxal. Is not involved in the vitamin B6 biosynthesis%3B Belongs to the aldo/keto reductase family%3B KEGG: nce:NCER_101329 aldehyde reductase gene gene2258 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02259 S100141_02260 S100141_02260 S100141_02260 2077347 2078564 - putative MFS-type transporter YtbD Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene2259 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02260 S100141_02261 S100141_02261 S100141_02261 2078721 2079098 + putative HTH-type transcriptional regulator YtcD DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH hxlR-type DNA-binding domain gene gene2260 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02261 S100141_02262 S100141_02262 pepE pepE 2079118 2079783 + Dipeptidase E Cytoplasm%3B Dipeptidase%3B Hydrolase%3B Protease%3B Serine protease%3B Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids%3B Belongs to the peptidase S51 family%3B KEGG: bli:BL00475 dipeptidase E gene gene2261 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02262 S100141_02263 S100141_02263 hemD hemD 2080094 2080921 - Uroporphyrinogen-III synthase KEGG: bsu:BSU12230 uroporphyrinogen-III synthase gene gene2262 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02263 S100141_02264 S100141_02264 S100141_02264 2081029 2081973 + hypothetical protein gene gene2263 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02264 S100141_02265 S100141_02265 S100141_02265 2082016 2082972 - Iron(3+)-hydroxamate-binding protein YxeB Cell membrane%3B Ion transport%3B Iron%3B Iron transport%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B Part of the ABC transporter complex FhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Partially required for the transport of desferrioxamine%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene2264 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02265 S100141_02266 S100141_02266 S100141_02266 2083050 2083949 - HTH-type transcriptional regulator CfxR Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Trans-acting transcriptional regulator of RuBisCO genes (cfxLS) expression. Contains 1 HTH lysR-type DNA-binding domain gene gene2265 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02266 S100141_02267 S100141_02267 S100141_02267 2084070 2085287 + putative transporter Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene2266 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02267 S100141_02268 S100141_02268 S100141_02268 2085436 2085819 + hypothetical protein gene gene2267 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02268 S100141_02269 S100141_02269 S100141_02269 2085844 2089068 - Unspecific monooxygenase Cytoplasm%3B Electron transport%3B FAD%3B Flavoprotein%3B FMN%3B Heme%3B Iron%3B Metal-binding%3B Monooxygenase%3B Multifunctional enzyme%3B NADP%3B Oxidoreductase%3B Transport%3B Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of a range of medium to long-chain fatty acids%2C with a preference for long-chain unsaturated and branched-chain fatty acids over saturated fatty acids. Hydroxylation of myristic acid occurs mainly at the omega-2 and omega-3 positions%2C in approximately equal proportions. Also displays a NADPH-dependent reductase activity in the C-terminal domain%2C which allows electron transfer from NADPH to the heme iron of the cytochrome P450 N- terminal domain%3B In the N-terminal sectio%3B belongs to the cytochrome P450 family%3B Contains 1 FAD-binding FR-type domain%3B Contains 1 flavodoxin-like domain%3B KEGG: bli:BL02398 cytochrome P450 / NADPH-cytochrome P450 reductase gene gene2268 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02269 S100141_02270 S100141_02270 S100141_02270 2089103 2089678 - HTH-type transcriptional repressor FatR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Negatively regulates the transcription of the fatR-cypB operon. Is displaced from its operator by a range of fatty acids such as oleate%2C linoleate and phytanate%2C thereby allowing transcription of the fatR-cypB operon%3B Contains 1 HTH tetR-type DNA-binding domain gene gene2269 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02270 S100141_02271 S100141_02271 wprA wprA 2089942 2093085 - Cell wall-associated protease Cell wall%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Protease%3B Secreted%3B Serine protease%3B Signal%3B Zymogen%3B CWBP52 is a serine-type protease that could be involved in proteoglycan peptide bridges%3B Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bld:BLi02850 cell wall-associated protease%3B Serine endopeptidases gene gene2270 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02271 S100141_02272 S100141_02272 S100141_02272 2093257 2093862 - Demethylmenaquinone methyltransferase Menaquinone biosynthesis%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family%3B KEGG: age:AA314_00425 demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1%2C4-benzoquinol methylase gene gene2271 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02272 S100141_02273 S100141_02273 S100141_02273 2094139 2094288 + hypothetical protein gene gene2272 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02273 S100141_02274 S100141_02274 S100141_02274 2094706 2094855 - uncharacterized protein gene gene2273 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02274 S100141_02275 S100141_02275 S100141_02275 2095263 2095496 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2274 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02275 S100141_02276 S100141_02276 mccB mccB 2095585 2096727 - Cystathionine gamma-lyase Amino-acid biosynthesis%3B Cytoplasm%3B Lyase%3B Methionine biosynthesis%3B Pyridoxal phosphate%3B The enzymatic degradation of amino acids in cheese is believed to generate aroma compounds and therefore to be essential for flavor development. Cystathionine beta-lyase (CBL) can convert cystathionine to homocysteine but is also able to catalyze an alpha%2C gamma elimination. With methionine as a substrate%2C it produces volatile sulfur compounds which are important for flavor formation in Gouda cheese. Belongs to the trans-sulfuration enzymes family%3B KEGG: bli:BL02018 cystathionine gamma-lyase / homocysteine desulfhydrase gene gene2275 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02276 S100141_02277 S100141_02277 S100141_02277 2096729 2097652 - Cysteine synthase Amino-acid biosynthesis%3B Cysteine biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Belongs to the cysteine synthase/cystathionine beta- synthase family gene gene2276 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02277 S100141_02278 S100141_02278 mtnN mtnN 2097704 2098399 - Adenosylhomocysteine nucleosidase Amino-acid biosynthesis%3B Hydrolase%3B Menaquinone biosynthesis%3B Methionine biosynthesis%3B Catalyzes the direct conversion of aminodeoxyfutalosine (AFL) into dehypoxanthine futalosine (DHFL) and adenine via the hydrolysis of the N-glycosidic bon%3B this reaction seems to represent an essential step in the menaquinone biosynthesis pathway in Campylobacter species. Also catalyzes the hydrolysis of 5'-methylthioadenosine (MTA) to adenine and 5'-methylthioribose. Can also probably use S-adenosylhomocysteine (SAH) as substrate%2C leading to adenine and S-ribosylhomocysteine. These other activities highlight the tremendous versatility of the enzyme%2C which also plays key roles in S-adenosylmethionine recycling and in the biosynthesis of the quorum-sensing molecule autoinducer-2. Shows negligible activity with futalosine (FL) as substrate%3B Belongs to the PNP/UDP phosphorylase family%3B KEGG: pat:Patl_0518 adenosylhomocysteine nucleosidase gene gene2277 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02278 S100141_02279 S100141_02279 yrrT yrrT 2098421 2099062 - putative methyltransferase Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Could be a S-adenosyl-L-methionine-dependent methyltransferase%3B Belongs to the methyltransferase superfamily. YrrT family%3B KEGG: bsu:BSU27280 putative AdoMet-dependent methyltransferase%3B Methyltransferases gene gene2278 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02279 S100141_02280 S100141_02280 S100141_02280 2099252 2099455 + uncharacterized protein Coiled coil. gene gene2279 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02280 S100141_02281 S100141_02281 S100141_02281 2099494 2100186 - putative membrane protein YrrS Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2280 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02281 S100141_02282 S100141_02282 S100141_02282 2100245 2101999 - Penicillin-binding protein 4B Cell cycle%3B Cell division%3B Cell membrane%3B Membrane%3B Signal-anchor%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Penicillin-binding protein with an unknown catalytic activity. Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis. Beta-lactamase inactivates the PBPs by acylating an essential serine residue in the active site of these proteins%2C thereby interrupting normal cell wall synthesis. Belongs to the transpeptidase family gene gene2281 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02282 S100141_02283 S100141_02283 S100141_02283 2102054 2102530 - Transcription elongation factor GreA Coiled coil%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through%2C resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides%3B Belongs to the GreA/GreB family gene gene2282 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02283 S100141_02284 S100141_02284 S100141_02284 2102770 2103405 - Uridine kinase ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the uridine kinase family%3B KEGG: bli:BL02025 uridine kinase gene gene2283 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02284 S100141_02285 S100141_02285 S100141_02285 2103410 2104678 - putative protease YrrO Hydrolase%3B Protease%3B Belongs to the peptidase U32 family%3B KEGG: bli:BL02026 putative protease%3B Acting on peptide bonds (peptidases) gene gene2284 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02285 S100141_02286 S100141_02286 S100141_02286 2104693 2105622 - putative protease YrrN Hydrolase%3B Protease%3B Belongs to the peptidase U32 family%3B KEGG: bsu:BSU27350 putative protease%3B Acting on peptide bonds (peptidases) gene gene2285 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02286 S100141_02287 S100141_02287 S100141_02287 2105619 2106281 - Caffeoyl-CoA O-methyltransferase Metal-binding%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O- methyltransferase family%3B KEGG: ctc:CTC01062 caffeoyl-CoA O-methyltransferase gene gene2286 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02287 S100141_02288 S100141_02288 S100141_02288 2106429 2107277 - UPF0755 protein YrrL Belongs to the UPF0755 family gene gene2287 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02288 S100141_02289 S100141_02289 S100141_02289 2107307 2107540 - UPF0755 protein YrrL Belongs to the UPF0755 family gene gene2288 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02289 S100141_02290 S100141_02290 S100141_02290 2107735 2108019 - UPF0473 protein Belongs to the UPF0473 family gene gene2289 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02290 S100141_02291 S100141_02291 ruvX ruvX 2108030 2108449 - Putative pre-16S rRNA nuclease Cytoplasm%3B Hydrolase%3B Nuclease%3B Ribosome biogenesis%3B Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA%3B Belongs to the YqgF nuclease family%3B KEGG: dao:Desac_2916 putative holliday junction resolvase%3B Acting on ester bonds gene gene2290 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02291 S100141_02292 S100141_02292 S100141_02292 2108456 2108722 - UPF0297 protein Belongs to the UPF0297 family%3B KEGG: snu:SPNA45_01835 putative holliday junction resolvase%3B Acting on ester bonds gene gene2291 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02292 S100141_02293 S100141_02293 aarS aarS 2108806 2111442 - Alanine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B RNA-binding%3B tRNA-binding%3B Zinc%3B Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: dno:DNO_0286 alanyl-tRNA synthetase gene gene2292 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02293 S100141_02294 S100141_02294 S100141_02294 2111793 2112851 - UPF0118 membrane protein YrrI Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0118 (PerM) family gene gene2293 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02294 S100141_02295 S100141_02295 S100141_02295 2113089 2113280 - uncharacterized protein gene gene2294 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02295 S100141_02296 S100141_02296 S100141_02296 2113296 2113760 - uncharacterized protein gene gene2295 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02296 S100141_02297 S100141_02297 recD recD 2113849 2116245 - Exodeoxyribonuclease V ATP-binding%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs%2C requires at least 10 bases of 5'-ssDNA for helicase activity%3B Belongs to the RecD family. RecD-like subfamily%3B KEGG: bli:BL02037 exodeoxyribonuclease V alpha subunit gene gene2296 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02297 S100141_02298 S100141_02298 S100141_02298 2116296 2116946 - TPR repeat-containing protein YrrB Repeat%3B TPR repeat%3B Could be an interacting mediator in the complex formation among RNA sulfuration components%2C RNA processing components%2C and aminoacyl-tRNA synthetases. Contains 6 TPR repeats gene gene2297 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02298 S100141_02299 S100141_02299 mnmA mnmA 2117040 2118158 - tRNA-specific 2-thiouridylase MnmA ATP-binding%3B Cytoplasm%3B Disulfide bond%3B Nucleotide-binding%3B RNA-binding%3B Transferase%3B tRNA processing%3B tRNA-binding%3B Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA%2C leading to the formation of s(2)U34%3B Belongs to the MnmA/TRMU family%3B KEGG: azl:AZL_020120 tRNA-specific 2-thiouridylase%3B Sulfurtransferases gene gene2298 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02299 S100141_02300 S100141_02300 iscS iscS 2118264 2119403 - Cysteine desulfurase Iron%3B Iron-sulfur%3B Metal-binding%3B Pyridoxal phosphate%3B Transferase%3B Catalyzes the removal of elemental sulfur from cysteine to produce alanine%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily%3B KEGG: tti:THITH_16475 cysteine desulfurase gene gene2299 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02300 S100141_02301 S100141_02301 S100141_02301 2119424 2119840 - HTH-type transcriptional regulator CymR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Master repressor of cysteine metabolism in B. subtilis. Controls the expression of genes involved either in cysteine synthesis from sulfide (cysK)%2C sulfonates (ssu)%2C or methionine (mccAB) or in cystine uptake (tcyP). Activity of CymR is positively regulated by CysK in response to cysteine availability. When cysteine is present%2C the pool of O-acetylserine (OAS) is low%2C which leads to the formation of a CymR-CysK complex and transcriptional repression of the CymR regulon occurs. In the absence of cysteine%2C the OAS pool is high and the CymR-CysK complex is mostly dissociated%2C leading to a faster dissociation of CymR from its DNA targets and the lifting of CymR-dependent repression%3B Contains 1 HTH rrf2-type DNA-binding domain gene gene2300 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02301 S100141_02302 S100141_02302 S100141_02302 2120415 2121680 + putative AAA domain-containing protein YrvN ATP-binding%3B Nucleotide-binding%3B Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily gene gene2301 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02302 S100141_02303 S100141_02303 S100141_02303 2121765 2122529 - tRNA threonylcarbamoyladenosine dehydratase ATP-binding%3B Ligase%3B Nucleotide-binding%3B Catalyzes the ATP-dependent dehydration of threonylcarbamoyladenosine at position 37 (t(6)A37) to form cyclic t(6)A37 (ct(6)A37) in tRNAs that read codons beginning with adenine%3B Belongs to the HesA/MoeB/ThiF family gene gene2302 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02303 S100141_02304 S100141_02304 darS darS 2122949 2124727 - Aspartate--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn)%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: bsu:BSU27550 aspartyl-tRNA synthetase gene gene2303 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02304 S100141_02305 S100141_02305 harS harS 2124742 2126016 - Histidine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: bsu:BSU27560 histidyl-tRNA synthetase gene gene2304 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02305 S100141_02306 S100141_02306 S100141_02306 2126391 2126555 - uncharacterized protein gene gene2305 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02306 S100141_02307 S100141_02307 S100141_02307 2126698 2128269 + N-acetylmuramoyl-L-alanine amidase Cell wall%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Metal-binding%3B Secreted%3B Signal%3B Zinc%3B Probably involved in cell-wall metabolism%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B KEGG: bli:BL01120 N-acetylmuramoyl-L-alanine amidase gene gene2306 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02307 S100141_02308 S100141_02308 dtd1 dtd1 2128297 2128740 - D-aminoacyl-tRNA deacylase Cytoplasm%3B Hydrolase%3B D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules%2C this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo%3B Belongs to the DTD family%3B KEGG: sml:Smlt4166 D-tyrosyl-tRNA(Tyr) deacylase%3B Acting on ester bonds gene gene2307 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02308 S100141_02309 S100141_02309 relA relA 2128754 2130955 - GTP diphosphokinase ATP-binding%3B GTP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase%3B In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp (By similarity)%3B Belongs to the RelA/SpoT family%3B Contains 1 ACT domain%3B Contains 1 HD domain%3B KEGG: bsu:BSU27600 GTP pyrophosphokinase gene gene2308 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02309 S100141_02310 S100141_02310 aprT aprT 2131126 2131638 - Adenine phosphoribosyltransferase Cytoplasm%3B Glycosyltransferase%3B Purine salvage%3B Transferase%3B Catalyzes a salvage reaction resulting in the formation of AMP%2C that is energically less costly than de novo synthesis%3B Belongs to the purine/pyrimidine phosphoribosyltransferase family%3B KEGG: bli:BL01126 adenine phosphoribosyltransferase gene gene2309 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02310 S100141_02311 S100141_02311 recJ recJ 2131656 2134004 - Single-stranded-DNA-specific exonuclease RecJ Coiled coil%3B DNA-binding%3B Exonuclease%3B Hydrolase%3B Nuclease%3B Putative single-stranded-DNA-specific exonuclease (By similarity). RecA thread formation during DNA double-strand break repair requires RecJ or AadAB%3B Belongs to the RecJ family%3B Contains 1 OB DNA-binding domain%3B KEGG: bsu:BSU27620 single-stranded-DNA-specific exonuclease%3B Acting on ester bonds gene gene2310 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02311 S100141_02312 S100141_02312 S100141_02312 2134076 2134369 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2311 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02312 S100141_02313 S100141_02313 S100141_02313 2134523 2136748 - Protein translocase subunit SecDF Cell membrane%3B Membrane%3B Protein transport%3B Translocation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Required for efficient translocation of secretory pre- proteins under conditions of hypersecretion but is not required for the release of mature proteins from the membrane%3B Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)%3B In the N-terminal sectio%3B belongs to the SecD/SecF family. SecD subfamily%3B In the C-terminal sectio%3B belongs to the SecD/SecF family. SecF subfamily gene gene2312 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02313 S100141_02314 S100141_02314 S100141_02314 2136785 2137081 - Post-transcriptional regulator ComN Competence%3B Cytoplasm%3B Required for post-transcription initiation control of the comE operon. Promotes the accumulation of its target comE mRNA to septal and polar sites gene gene2313 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02314 S100141_02315 S100141_02315 S100141_02315 2137199 2138752 + Stage V sporulation protein Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Involved%2C directly or indirectly%2C in spore cortex biosynthesis. Affects only indirectly the expression of late sporulation genes. Belongs to the polysaccharide synthase family gene gene2314 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02315 S100141_02316 S100141_02316 S100141_02316 2138761 2139411 - UPF0702 transmembrane protein YrbG Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0702 family gene gene2315 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02316 S100141_02317 S100141_02317 S100141_02317 2139567 2139950 + putative membrane protein YrzE Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2316 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02317 S100141_02318 S100141_02318 S100141_02318 2140132 2140392 - UPF0092 membrane protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0092 family gene gene2317 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02318 S100141_02319 S100141_02319 S100141_02319 2140442 2141587 - tRNA-guanine(34) transglycosylase Glycosyltransferase%3B Metal-binding%3B Queuosine biosynthesis%3B Transferase%3B tRNA processing%3B Zinc%3B Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp%2C -Asn%2C -His and -Tyr). After this exchange%2C a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine%2C resulting in the hypermodified nucleoside queuosine (Q) (7-(((4%2C5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)%3B Belongs to the queuine tRNA-ribosyltransferase family%3B KEGG: bsu:BSU27710 queuine tRNA-ribosyltransferase gene gene2318 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02319 S100141_02320 S100141_02320 queA queA 2141616 2142644 - S-adenosylmethionine:tRNA ribosyltransferase-isomerase Cytoplasm%3B Queuosine biosynthesis%3B S-adenosyl-L-methionine%3B Transferase%3B Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)%3B Belongs to the QueA family%3B KEGG: atu:Atu1678 S-adenosylmethionine:tRNA ribosyltransferase-isomerase gene gene2319 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02320 S100141_02321 S100141_02321 ruvB ruvB 2142685 2142885 - DNA helicase Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B KEGG: bamp:B938_12840 holliday junction DNA helicase RuvB%3B overlaps another CDS with the same product name gene gene2320 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02321 S100141_02322 S100141_02322 S100141_02322 2142878 2143882 - DNA helicase ATP-binding%3B DNA damage%3B DNA recombination%3B DNA repair%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B SOS response%3B RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing%3B Belongs to the RuvB family%3B KEGG: bsu:BSU27730 holliday junction DNA helicase RuvB%3B overlaps another CDS with the same product name gene gene2321 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02322 S100141_02323 S100141_02323 ruvA ruvA 2143892 2144497 - DNA helicase ATP-binding%3B DNA damage%3B DNA recombination%3B DNA repair%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B SOS response%3B RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates%2C in the presence of DNA%2C the weak ATPase activity of RuvB%3B Belongs to the RuvA family%3B KEGG: bsu:BSU27740 holliday junction DNA helicase RuvA gene gene2322 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02323 S100141_02324 S100141_02324 S100141_02324 2144620 2145141 - Protein BofC Signal%3B Sporulation. gene gene2323 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02324 S100141_02325 S100141_02325 S100141_02325 2145384 2146034 + Putative serine/threonine-protein kinase YrzF ATP-binding%3B Kinase%3B Nucleotide-binding%3B Serine/threonine-protein kinase%3B Transferase%3B Belongs to the protein kinase superfamily. Ser/Thr protein kinase family%3B Contains 1 protein kinase domain%3B KEGG: bcz:BCZK2452 null%3B Phosphotransferases with an alcohol group as acceptor gene gene2324 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02325 S100141_02326 S100141_02326 S100141_02326 2146105 2146227 + hypothetical protein gene gene2325 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02326 S100141_02327 S100141_02327 S100141_02327 2146312 2146491 - Small%2C acid-soluble spore protein Sporulation%3B Belongs to the SspH family gene gene2326 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02327 S100141_02328 S100141_02328 S100141_02328 2146587 2147051 - uncharacterized protein Metal-binding%3B Phosphoprotein%3B Belongs to the DinB family gene gene2327 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02328 S100141_02329 S100141_02329 S100141_02329 2147112 2147822 - UPF0714 protein YjqB Belongs to the UPF0714 family gene gene2328 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02329 S100141_02330 S100141_02330 S100141_02330 2148236 2148415 + uncharacterized protein gene gene2329 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02330 S100141_02331 S100141_02331 S100141_02331 2148507 2148833 - hypothetical protein gene gene2330 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02331 S100141_02332 S100141_02332 glgC glgC 2148975 2149697 - Glucose-1-phosphate adenylyltransferase Cytoplasm%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Belongs to the TACO1 family%3B KEGG: pmf:P9303_05381 glucose-1-phosphate adenylyltransferase gene gene2331 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02332 S100141_02333 S100141_02333 S100141_02333 2149824 2150459 - Sporulation cortex protein CoxA Signal%3B Sporulation. gene gene2332 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02333 S100141_02334 S100141_02334 S100141_02334 2150632 2151684 - Spore coat assembly protein ExsA Repeat%3B Sporulation%3B Required for the normal assembly and anchoring of both the spore coat and the exosporium layers%3B Contains 1 LysM repeat%3B To B. subtilis SafA gene gene2333 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02334 S100141_02335 S100141_02335 nadA nadA 2151800 2152909 - Quinolinate synthase 4Fe-4S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Pyridine nucleotide biosynthesis%3B Transferase%3B Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate%3B Belongs to the quinolinate synthase A family. Type 3 subfamily%3B KEGG: bli:BL01153 quinolinate synthase gene gene2334 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02335 S100141_02336 S100141_02336 nadC nadC 2152931 2153770 - Nicotinate-nucleotide diphosphorylase (carboxylating) Alternative splicing%3B Chloroplast%3B Glycosyltransferase%3B Plastid%3B Pyridine nucleotide biosynthesis%3B Transferase%3B Transit peptide%3B Involved in the catabolism of quinolinic acid (QA)%3B Belongs to the NadC/ModD family%3B KEGG: bli:BL01154 nicotinate-nucleotide pyrophosphorylase (carboxylating) gene gene2335 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02336 S100141_02337 S100141_02337 nadB nadB 2153751 2155325 - L-aspartate oxidase Cytoplasm%3B FAD%3B Flavoprotein%3B Oxidoreductase%3B Pyridine nucleotide biosynthesis%3B Catalyzes the oxidation of L-aspartate to iminoaspartate. Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily%3B KEGG: bli:BL01155 L-aspartate oxidase gene gene2336 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02337 S100141_02338 S100141_02338 S100141_02338 2155426 2156604 + Cysteine desulfurase Iron%3B Iron-sulfur%3B Metal-binding%3B Pyridoxal phosphate%3B Transferase%3B Catalyzes the removal of elemental sulfur from cysteine to produce alanine (By similarity). Seems to be required for NAD biosynthesis (PubMed:8444804)%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily%3B KEGG: ppf:Pput_1517 cysteine desulfurase gene gene2337 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02338 S100141_02339 S100141_02339 S100141_02339 2156573 2157115 + Transcription repressor NadR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B In the presence of nicotinic acid represses transcription of the nadBCA and nifS-nadR operons. Also binds to DNA upstream of the niaP gene%2C probably regulating it as well. May bind nicotinic acid gene gene2338 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02339 S100141_02340 S100141_02340 S100141_02340 2157159 2158028 - Prephenate dehydratase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Lyase%3B Phenylalanine biosynthesis%3B Contains 1 ACT domain%3B Contains 1 prephenate dehydratase domain%3B KEGG: bld:BLi02917 prephenate dehydratase gene gene2339 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02340 S100141_02341 S100141_02341 pheB pheB 2158037 2158480 - Chorismate mutase Belongs to the UPF0735 family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU27910 chorismate mutase gene gene2340 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02341 S100141_02342 S100141_02342 S100141_02342 2158594 2159880 - GTPase Obg Cytoplasm%3B GTP-binding%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B An essential GTPase which binds GTP%2C GDP and possibly (p)ppGpp with moderate affinity%2C with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle%2C stress response%2C ribosome biogenesis and in those bacteria that undergo differentiation%2C in morphogenesis control%3B Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family%3B Contains 1 OBG-type G (guanine nucleotide-binding) domain gene gene2341 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02342 S100141_02343 S100141_02343 S100141_02343 2159913 2160491 - Sporulation initiation phosphotransferase Cytoplasm%3B Kinase%3B Phosphoprotein%3B Sensory transduction%3B Sporulation%3B Transferase%3B KEGG: bli:BL01158 stage 0 sporulation protein B (sporulation initiation phosphotransferase)%3B Transferring phosphorus-containing groups gene gene2342 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02343 S100141_02344 S100141_02344 S100141_02344 2160717 2160998 - 50S ribosomal protein L27 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L27P family gene gene2343 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02344 S100141_02345 S100141_02345 S100141_02345 2161011 2161352 - uncharacterized protein To M. genitalium MG233 gene gene2344 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02345 S100141_02346 S100141_02346 S100141_02346 2161365 2161673 - 50S ribosomal protein L21 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B This protein binds to 23S rRNA in the presence of protein L20%3B Belongs to the ribosomal protein L21P family gene gene2345 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02346 S100141_02347 S100141_02347 S100141_02347 2161830 2162696 - Stage IV sporulation protein FB Hydrolase%3B Membrane%3B Metal-binding%3B Metalloprotease%3B Protease%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Zinc%3B Implicated in the coupling of mother cell to forespore gene expression. Required for spore formation. Processes the pro- sigma K factor. Belongs to the peptidase M50B family%3B KEGG: bli:BL05293 stage IV sporulation protein FB%3B Metalloendopeptidases gene gene2346 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02347 S100141_02348 S100141_02348 S100141_02348 2162689 2163480 - Stage IV sporulation protein FA Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix. gene gene2347 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02348 S100141_02349 S100141_02349 S100141_02349 2163626 2164054 + uncharacterized protein Belongs to the AHA1 family gene gene2348 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02349 S100141_02350 S100141_02350 S100141_02350 2164054 2164374 + Transcriptional repressor SdpR Cytoplasm%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Represses the transcription of the sdpIR operon and of several other operons that probably contribute to delaying commitment to sporulation%3B Contains 1 HTH arsR-type DNA-binding domain gene gene2349 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02350 S100141_02351 S100141_02351 S100141_02351 2164419 2165225 - Septum site-determining protein MinD ATP-binding%3B Cell cycle%3B Cell division%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Septation%3B ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings (By similarity)%3B Belongs to the ParA family. MinD subfamily gene gene2350 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02351 S100141_02352 S100141_02352 S100141_02352 2165228 2165950 - putative septum site-determining protein MinC Cell cycle%3B Cell division%3B Septation%3B Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization%3B Belongs to the MinC family gene gene2351 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02352 S100141_02353 S100141_02353 S100141_02353 2165963 2166481 - Rod shape-determining protein MreD Cell membrane%3B Cell shape%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins (By similarity)%3B Belongs to the MreD family gene gene2352 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02353 S100141_02354 S100141_02354 S100141_02354 2166478 2167386 - Cell shape-determining protein MreC Cell shape%3B Coiled coil%3B Signal%3B Involved in formation and maintenance of cell shape%3B Belongs to the MreC family gene gene2353 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02354 S100141_02355 S100141_02355 S100141_02355 2167417 2168427 - Rod shape-determining protein MreB Cell shape%3B Involved in formation of the rod shape of the cell%3B Belongs to the FtsA/MreB family gene gene2354 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02355 S100141_02356 S100141_02356 S100141_02356 2168515 2168808 - UPF0758 protein Belongs to the UPF0758 family gene gene2355 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02356 S100141_02357 S100141_02357 S100141_02357 2169027 2169611 + hypothetical protein gene gene2356 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02357 S100141_02358 S100141_02358 S100141_02358 2169710 2170078 + SPBc2 prophage-derived uncharacterized protein YolD gene gene2357 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02358 S100141_02359 S100141_02359 S100141_02359 2170192 2170311 - hypothetical protein gene gene2358 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02359 S100141_02360 S100141_02360 S100141_02360 2170301 2171422 - Response regulator aspartate phosphatase Hydrolase%3B Protein phosphatase%3B Repeat%3B TPR repeat%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bli:BL02161 response regulator aspartate phosphatase I%3B Acting on ester bonds gene gene2359 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02360 S100141_02361 S100141_02361 S100141_02361 2171675 2173291 + putative ribonuclease YokI Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 449-571) inhibits growth upon expression in E. coli which is neutralized by cognate antitoxin YokJ%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene2360 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02361 S100141_02362 S100141_02362 S100141_02362 2173304 2173720 + hypothetical protein gene gene2361 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02362 S100141_02363 S100141_02363 S100141_02363 2173751 2174704 - Lysozyme M1 Disulfide bond%3B Glycosidase%3B Hydrolase%3B Secreted%3B Signal%3B This enzyme has both lysozyme (acetylmuramidase) and diacetylmuramidase activities. Belongs to the glycosyl hydrolase 25 family gene gene2362 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02363 S100141_02364 S100141_02364 S100141_02364 2174752 2175015 - SPBc2 prophage-derived protein BhlB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B May be involved in the secretion of the autolysin BlyA. Belongs to the SPP1 holin family gene gene2363 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02364 S100141_02365 S100141_02365 S100141_02365 2175031 2175324 - putative 11.0 kDa protein in cwlL 5'region To B. licheniformis xpaL1 and to B. subtilis XhlA gene gene2364 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02365 S100141_02366 S100141_02366 S100141_02366 2175364 2175546 - hypothetical protein gene gene2365 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02366 S100141_02367 S100141_02367 S100141_02367 2175543 2175866 - SPBc2 prophage-derived uncharacterized protein YomQ gene gene2366 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02367 S100141_02368 S100141_02368 S100141_02368 2175879 2177318 - Phage-like element PBSX protein XkdV To B. subtilis YqcC gene gene2367 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02368 S100141_02369 S100141_02369 S100141_02369 2177357 2178910 - hypothetical protein gene gene2368 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02369 S100141_02370 S100141_02370 S100141_02370 2178947 2180656 - N-acetylmuramoyl-L-alanine amidase Cell wall%3B Cell wall biogenesis/degradation%3B Glycosidase%3B Hydrolase%3B Magnesium%3B Secreted%3B Signal%3B Is the major glucosaminidase responsible for peptidoglycan structural determination during vegetative growth. Acts processively from the ends of the glycan strands. Also plays a role in motility%2C chemotaxis and cell division%3B Belongs to the glycosyl hydrolase 73 family%3B KEGG: smu:SMU_76 N-acetylmuramoyl-L-alanine amidase gene gene2369 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02370 S100141_02371 S100141_02371 S100141_02371 2180669 2181505 - hypothetical protein gene gene2370 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02371 S100141_02372 S100141_02372 S100141_02372 2181505 2185395 - Tape measure protein Host membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Viral tail assembly%3B Virus exit from host cell%3B Plays a role in virion tail formation. The length of the tape measure protein is proportional to the length of the phage's tail gene gene2371 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02372 S100141_02373 S100141_02373 S100141_02373 2185593 2185928 - hypothetical protein gene gene2372 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02373 S100141_02374 S100141_02374 S100141_02374 2185989 2186597 - hypothetical protein gene gene2373 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02374 S100141_02375 S100141_02375 S100141_02375 2186597 2186977 - hypothetical protein gene gene2374 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02375 S100141_02376 S100141_02376 S100141_02376 2186974 2187357 - hypothetical protein gene gene2375 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02376 S100141_02377 S100141_02377 S100141_02377 2187654 2188004 - hypothetical protein gene gene2376 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02377 S100141_02378 S100141_02378 S100141_02378 2188020 2188469 - Collagen alpha-1(V) chain Collagen%3B Extracellular matrix%3B Heparin-binding%3B Hydroxylation%3B Repeat%3B Secreted%3B Signal%3B Sulfation%3B Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA%2C heparan sulfate%2C thrombospondin%2C heparin%2C and insulin (By similarity)%3B Belongs to the fibrillar collagen family%3B Contains 1 fibrillar collagen NC1 domain%3B Contains 1 laminin G-like domain gene gene2377 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02378 S100141_02379 S100141_02379 S100141_02379 2188495 2189811 - hypothetical protein gene gene2378 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02379 S100141_02380 S100141_02380 S100141_02380 2189852 2190481 - hypothetical protein gene gene2379 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02380 S100141_02381 S100141_02381 S100141_02381 2190471 2191715 - hypothetical protein gene gene2380 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02381 S100141_02382 S100141_02382 S100141_02382 2191721 2191891 - hypothetical protein gene gene2381 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02382 S100141_02383 S100141_02383 S100141_02383 2191903 2193612 - uncharacterized protein Belongs to the phage terminase family gene gene2382 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02383 S100141_02384 S100141_02384 S100141_02384 2193612 2194145 - hypothetical protein gene gene2383 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02384 S100141_02385 S100141_02385 S100141_02385 2194232 2194558 - hypothetical protein gene gene2384 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02385 S100141_02386 S100141_02386 S100141_02386 2194527 2194901 - hypothetical protein gene gene2385 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02386 S100141_02387 S100141_02387 S100141_02387 2195061 2195705 - hypothetical protein gene gene2386 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02387 S100141_02388 S100141_02388 S100141_02388 2195924 2196148 - Spore coat protein Sporulation. gene gene2387 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02388 S100141_02389 S100141_02389 S100141_02389 2196898 2197278 - hypothetical protein gene gene2388 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02389 S100141_02390 S100141_02390 S100141_02390 2197296 2197394 - hypothetical protein gene gene2389 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02390 S100141_02391 S100141_02391 S100141_02391 2197391 2197768 - hypothetical protein gene gene2390 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02391 S100141_02392 S100141_02392 S100141_02392 2197784 2198299 - hypothetical protein gene gene2391 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02392 S100141_02393 S100141_02393 S100141_02393 2198303 2198473 - hypothetical protein gene gene2392 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02393 S100141_02394 S100141_02394 S100141_02394 2198470 2199009 - hypothetical protein gene gene2393 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02394 S100141_02395 S100141_02395 S100141_02395 2199006 2199461 - hypothetical protein gene gene2394 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02395 S100141_02396 S100141_02396 S100141_02396 2199421 2199876 - hypothetical protein gene gene2395 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02396 S100141_02397 S100141_02397 S100141_02397 2200014 2202446 - Putative helicase L207/L206 ATP-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Contains 1 SF3 helicase domain gene gene2396 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02397 S100141_02398 S100141_02398 S100141_02398 2202507 2202947 - hypothetical protein gene gene2397 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02398 S100141_02399 S100141_02399 S100141_02399 2202966 2203319 - hypothetical protein gene gene2398 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02399 S100141_02400 S100141_02400 S100141_02400 2203309 2204244 - hypothetical protein gene gene2399 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02400 S100141_02401 S100141_02401 S100141_02401 2204248 2204805 - hypothetical protein gene gene2400 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02401 S100141_02402 S100141_02402 S100141_02402 2204898 2205002 - hypothetical protein gene gene2401 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02402 S100141_02403 S100141_02403 S100141_02403 2204999 2205268 - hypothetical protein gene gene2402 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02403 S100141_02404 S100141_02404 S100141_02404 2205265 2205456 - hypothetical protein gene gene2403 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02404 S100141_02405 S100141_02405 S100141_02405 2205472 2205606 - hypothetical protein gene gene2404 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02405 S100141_02406 S100141_02406 S100141_02406 2205607 2205846 - ImmF control region 10 kDa protein DNA-binding%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene2405 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02406 S100141_02407 S100141_02407 S100141_02407 2206096 2206539 + Repressor LexA DNA-binding%3B Early protein%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH cro/C1-type DNA-binding domain%3B KEGG: cpas:Clopa_0551 repressor LexA gene gene2406 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02407 S100141_02408 S100141_02408 S100141_02408 2206643 2207050 + putative immunity region protein gene gene2407 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02408 S100141_02409 S100141_02409 S100141_02409 2207090 2208478 + putative immunity region protein DNA integration%3B DNA invertase%3B DNA recombination%3B DNA-binding%3B Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene2408 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02409 S100141_02410 S100141_02410 S100141_02410 2208491 2208877 - UPF0758 protein Belongs to the UPF0758 family gene gene2409 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02410 S100141_02411 S100141_02411 S100141_02411 2208932 2209504 - Septum formation protein Maf Cytoplasm%3B Involved in septum formation%3B Belongs to the maf family gene gene2410 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02411 S100141_02412 S100141_02412 S100141_02412 2209658 2210689 - Stage II sporulation protein Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Involved in endospore development. Contains 1 SPOR domain gene gene2411 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02412 S100141_02413 S100141_02413 comC comC 2210893 2211642 - Type 4 prepilin-like protein leader peptide-processing enzyme Cell membrane%3B Competence%3B Hydrolase%3B Membrane%3B Methyltransferase%3B Multifunctional enzyme%3B Protease%3B S-adenosyl-L-methionine%3B Sporulation%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue%3B Belongs to the peptidase A24 family%3B KEGG: bli:BL00633 leader peptidase (prepilin peptidase) / N-methyltransferase%3B Prepilin peptidase gene gene2412 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02413 S100141_02414 S100141_02414 folC folC 2211785 2213089 - Dihydrofolate synthase ATP-binding%3B Folate biosynthesis%3B Ligase%3B Magnesium%3B Metal-binding%3B Multifunctional enzyme%3B Nucleotide-binding%3B Transferase%3B Can complement an H. volcanii mutant strain that is thymidine auxotroph because it lacks the two dihydrofolate reductase genes encoded by hdrA and hdrB%3B In the N-terminal sectio%3B belongs to the folylpolyglutamate synthase family%3B In the C-terminal sectio%3B belongs to the DHPS family%3B Contains 1 pterin-binding domain%3B KEGG: bld:BLi02937 dihydrofolate synthase / folylpolyglutamate synthase gene gene2413 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02414 S100141_02415 S100141_02415 varS varS 2213165 2215807 - Valine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Coiled coil%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine%2C to avoid such errors%2C it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner%3B Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily%3B KEGG: rpi:Rpic_2441 valyl-tRNA synthetase gene gene2414 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02415 S100141_02416 S100141_02416 S100141_02416 2216269 2216460 + putative membrane protein YszA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2415 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02416 S100141_02417 S100141_02417 S100141_02417 2216480 2217502 - uncharacterized protein gene gene2416 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02417 S100141_02418 S100141_02418 S100141_02418 2217530 2218987 - Stage VI sporulation protein D Sporulation. gene gene2417 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02418 S100141_02419 S100141_02419 hemL hemL 2219136 2220431 - Glutamate-1-semialdehyde 2%2C1-aminomutase Cytoplasm%3B Isomerase%3B Porphyrin biosynthesis%3B Pyridoxal phosphate%3B Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily%3B KEGG: bsu:BSU28120 glutamate-1-semialdehyde 2%2C1-aminomutase gene gene2418 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02419 S100141_02420 S100141_02420 hemB hemB 2220457 2221431 - Porphobilinogen synthase Heme biosynthesis%3B Lyase%3B Magnesium%3B Metal-binding%3B Porphyrin biosynthesis%3B Zinc%3B Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit%2C each at a distinct site%2C and catalyzes their condensation to form porphobilinogen (By similarity)%3B Belongs to the ALAD family%3B KEGG: bli:BL00627 porphobilinogen synthase gene gene2419 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02420 S100141_02421 S100141_02421 S100141_02421 2221435 2222226 - Uroporphyrinogen-III synthase Lyase%3B Methyltransferase%3B Multifunctional enzyme%3B Porphyrin biosynthesis%3B S-adenosyl-L-methionine%3B Transferase%3B May catalyze sequential reactions to synthesize uroporphyrinogen III from hydroxymethylbilane (HMB) and then precorrin-2%2C which are intermediate compounds in both vitamin B12 and siroheme biosyntheses%3B In the N-terminal sectio%3B belongs to the precorrin methyltransferase family%3B In the C-terminal sectio%3B belongs to the uroporphyrinogen-III synthase family%3B KEGG: bli:BL00626 uroporphyrinogen-III synthase gene gene2420 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02421 S100141_02422 S100141_02422 hemC hemC 2222216 2223157 - Hydroxymethylbilane synthase Porphyrin biosynthesis%3B Transferase%3B Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps%3B Belongs to the HMBS family%3B KEGG: bli:BL00625 hydroxymethylbilane synthase gene gene2421 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02422 S100141_02423 S100141_02423 S100141_02423 2223197 2224027 - Protein HemX Cell membrane%3B Membrane%3B Porphyrin biosynthesis%3B Transmembrane%3B Transmembrane helix%3B Required for HemL synthesis. To M. leprae U1620K gene gene2422 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02423 S100141_02424 S100141_02424 hemA hemA 2224033 2225418 - Glutamyl-tRNA reductase NADP%3B Oxidoreductase%3B Porphyrin biosynthesis%3B Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)%3B Belongs to the glutamyl-tRNA reductase family%3B KEGG: bay:RBAM_025230 glutamyl-tRNA reductase gene gene2423 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02424 S100141_02425 S100141_02425 S100141_02425 2225583 2226068 + putative membrane protein YsxD Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2424 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02425 S100141_02426 S100141_02426 S100141_02426 2226117 2226704 - putative GTP-binding protein EngB Cell cycle%3B Cell division%3B GTP-binding%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Septation%3B Necessary for normal cell division and for the maintenance of normal septation%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. EngB GTPase family%3B Contains 1 EngB-type G (guanine nucleotide-binding) domain gene gene2425 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02426 S100141_02427 S100141_02427 S100141_02427 2226701 2229025 - Endopeptidase La ATP-binding%3B Cytoplasm%3B Hydrolase%3B Nucleotide-binding%3B Protease%3B Serine protease%3B Stress response%3B ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Binds to DNA in a double-stranded%2C site-specific manner%3B Belongs to the peptidase S16 family%3B Contains 1 Lon domain%3B KEGG: bli:BL00621 ATP-dependent Lon protease gene gene2426 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02427 S100141_02428 S100141_02428 lonB lonB 2229244 2230899 - Lon protease ATP-binding%3B Cytoplasm%3B Hydrolase%3B Nucleotide-binding%3B Protease%3B Serine protease%3B Stress response%3B ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Binds to DNA in a double-stranded%2C site-specific manner (By similarity)%3B Belongs to the peptidase S16 family%3B KEGG: bli:BL00620 Lon-like ATP-dependent protease%3B Serine endopeptidases gene gene2427 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02428 S100141_02429 S100141_02429 S100141_02429 2231082 2232347 - ATP-dependent Clp protease ATP-binding subunit ClpX ATP-binding%3B Chaperone%3B Metal-binding%3B Nucleotide-binding%3B Zinc%3B Zinc-finger%3B ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP%3B Belongs to the ClpX chaperone family gene gene2428 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02429 S100141_02430 S100141_02430 S100141_02430 2232616 2233890 - Trigger factor Cell cycle%3B Cell division%3B Chaperone%3B Cytoplasm%3B Isomerase%3B Rotamase%3B Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase%3B Belongs to the FKBP-type PPIase family. Tig subfamily%3B Contains 1 PPIase FKBP-type domain gene gene2429 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02430 S100141_02431 S100141_02431 S100141_02431 2234117 2235124 - TPR repeat-containing protein YsoA Repeat%3B TPR repeat%3B Contains 3 TPR repeats gene gene2430 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02431 S100141_02432 S100141_02432 leuD leuD 2235254 2235853 - 3-isopropylmalate dehydratase Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Leucine biosynthesis%3B Lyase%3B Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate%2C via the formation of 2-isopropylmaleate%3B Belongs to the LeuD family. LeuD type 1 subfamily%3B KEGG: bli:BL00615 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit gene gene2431 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02432 S100141_02433 S100141_02433 leuC leuC 2235866 2237284 - 3-isopropylmalate dehydratase 4Fe-4S%3B Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Iron%3B Iron-sulfur%3B Leucine biosynthesis%3B Lyase%3B Metal-binding%3B Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate%2C via the formation of 2-isopropylmaleate%3B Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily%3B KEGG: bsu:BSU28260 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit gene gene2432 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02433 S100141_02434 S100141_02434 leuB leuB 2237318 2238430 - 3-isopropylmalate dehydrogenase Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Cytoplasm%3B Leucine biosynthesis%3B Magnesium%3B Manganese%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate%3B Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily%3B KEGG: xft:PD1397 3-isopropylmalate dehydrogenase gene gene2433 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02434 S100141_02435 S100141_02435 leuA leuA 2238458 2240014 - 2-isopropylmalate synthase Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Leucine biosynthesis%3B Transferase%3B Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)%3B Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily%3B KEGG: dgg:DGI_2503 2-isopropylmalate synthase gene gene2434 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02435 S100141_02436 S100141_02436 ilvC ilvC 2240001 2241029 - Ketol-acid reductoisomerase (NADP(+)) Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B NADP%3B Oxidoreductase%3B Belongs to the ketol-acid reductoisomerase family%3B KEGG: bsu:BSU28290 ketol-acid reductoisomerase gene gene2435 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02436 S100141_02437 S100141_02437 ilvH ilvH 2241053 2241571 - Acetolactate synthase Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Transferase%3B Belongs to the acetolactate synthase small subunit family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU28300 acetolactate synthase I/III small subunit%3B overlaps another CDS with the same product name gene gene2436 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02437 S100141_02438 S100141_02438 ilvB ilvB 2241568 2243292 - Acetolactate synthase Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B FAD%3B Flavoprotein%3B Magnesium%3B Metal-binding%3B Thiamine pyrophosphate%3B Transferase%3B Belongs to the TPP enzyme family%3B KEGG: bsu:BSU28310 acetolactate synthase I/II/III large subunit%3B overlaps another CDS with the same product name gene gene2437 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02438 S100141_02439 S100141_02439 ilvE ilvE 2243717 2244631 - Branched-chain-amino-acid transaminase Aminotransferase%3B Pyridoxal phosphate%3B Transferase%3B Acts on the D-isomers of alanine%2C leucine%2C aspartate%2C glutamate%2C aminobutyrate%2C norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction. The second half-reaction is the reverse of the first%2C transferring the amino group from the pyridoxamine to a second alpha-keto acid to form the product D- amino acid via a ping-pong mechanism. This is an important process in the formation of D-alanine and D-glutamate%2C which are essential bacterial cell wall components (By similarity)%3B Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bli:BL00607 branched-chain amino acid aminotransferase gene gene2438 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02439 S100141_02440 S100141_02440 S100141_02440 2245085 2245315 + hypothetical protein gene gene2439 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02440 S100141_02441 S100141_02441 gdhA gdhA 2245358 2246740 - Glutamate dehydrogenase (NADP(+)) NADP%3B Oxidoreductase%3B Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia%3B Belongs to the Glu/Leu/Phe/Val dehydrogenases family%3B KEGG: bli:BL00756 glutamate dehydrogenase (NADP+) gene gene2440 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02441 S100141_02442 S100141_02442 S100141_02442 2247153 2247407 + hypothetical protein gene gene2441 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02442 S100141_02443 S100141_02443 S100141_02443 2247451 2247942 - PERQ amino acid-rich with GYF domain-containing protein May play a role in tyrosine kinase receptor signaling regulation%3B Belongs to the PERQ family%3B Contains 1 GYF domain gene gene2442 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02443 S100141_02444 S100141_02444 S100141_02444 2248378 2248593 - Phage-like element PBSX protein XkdE Belongs to the phage portal family. PBSX subfamily gene gene2443 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02444 S100141_02445 S100141_02445 S100141_02445 2248597 2249892 - PBSX phage terminase large subunit Viral genome packaging%3B Virus exit from host cell%3B Functions as a terminase. To B. subtilis YqaT and phage SPP1 terminase large subunit gene gene2444 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02445 S100141_02446 S100141_02446 S100141_02446 2249889 2250749 - hypothetical protein gene gene2445 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02446 S100141_02447 S100141_02447 S100141_02447 2250796 2251044 - hypothetical protein gene gene2446 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02447 S100141_02448 S100141_02448 S100141_02448 2251172 2252197 - DNA (cytosine-5-)-methyltransferase Methyltransferase%3B Restriction system%3B S-adenosyl-L-methionine%3B Transferase%3B This methylase recognizes the double-stranded sequence GTGCAC%2C causes specific methylation on C-? on both strands%2C and protects the DNA from cleavage by the ApaLI endonuclease. Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family%3B Contains 1 SAM-dependent MTase C5-type domain%3B KEGG: bld:BLi02974 DNA (cytosine-5)-methyltransferase 1 gene gene2447 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02448 S100141_02449 S100141_02449 S100141_02449 2252346 2252537 - hypothetical protein gene gene2448 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02449 S100141_02450 S100141_02450 S100141_02450 2252568 2252855 - hypothetical protein gene gene2449 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02450 S100141_02451 S100141_02451 S100141_02451 2252950 2253429 - putative antitoxin YezG Coiled coil%3B Probable antitoxin component of a toxin-antitoxin (TA) module. Probably neutralizes the ability to inhibit growth of cognate toxin YeeF. Probably does not have antitoxin activity on other toxins with the LXG toxin domain (Probable) gene gene2450 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02451 S100141_02452 S100141_02452 S100141_02452 2253435 2255429 - Ribonuclease YxiD Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene2451 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02452 S100141_02453 S100141_02453 rapK rapK 2255623 2256813 + Response regulator aspartate phosphatase Hydrolase%3B Protein phosphatase%3B Repeat%3B TPR repeat%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bpu:BPUM_3641 response regulator aspartate phosphatase K%3B Acting on ester bonds gene gene2452 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02453 S100141_02454 S100141_02454 S100141_02454 2256810 2256941 + hypothetical protein gene gene2453 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02454 S100141_02455 S100141_02455 S100141_02455 2257036 2257284 - hypothetical protein gene gene2454 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02455 S100141_02456 S100141_02456 S100141_02456 2257533 2257682 - hypothetical protein gene gene2455 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02456 S100141_02457 S100141_02457 S100141_02457 2257810 2257886 - tRNA-Arg tRNA gene2456 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02457 S100141_02458 S100141_02458 S100141_02458 2258006 2258527 - Putative metallophosphoesterase YsnB Hydrolase%3B Belongs to the metallophosphoesterase superfamily. YfcE family gene gene2457 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02458 S100141_02459 S100141_02459 rdgB rdgB 2258544 2259134 - XTP/dITP diphosphatase Hydrolase%3B Magnesium%3B Manganese%3B Metal-binding%3B Nucleotide metabolism%3B Nucleotide-binding%3B Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP/dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool%2C thus preventing their incorporation into DNA and avoiding chromosomal lesions%3B Belongs to the HAM1 NTPase family%3B KEGG: gme:Gmet_1875 XTP/dITP diphosphohydrolase gene gene2458 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02459 S100141_02460 S100141_02460 S100141_02460 2259156 2259896 - tRNA nucleotidyltransferase Nucleotidyltransferase%3B Transferase%3B tRNA processing%3B Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates%3B Belongs to the RNase PH family%3B KEGG: bli:BL00312 ribonuclease PH gene gene2459 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02460 S100141_02461 S100141_02461 S100141_02461 2260022 2261131 - Spore germination protein GerM Germination%3B Sporulation. gene gene2460 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02461 S100141_02462 S100141_02462 murI murI 2261283 2262098 - Glutamate racemase Cell shape%3B Cell wall biogenesis/degradation%3B Isomerase%3B Peptidoglycan synthesis%3B Provides the (R)-glutamate required for cell wall biosynthesis%3B Belongs to the aspartate/glutamate racemases family%3B KEGG: bsu:BSU28390 glutamate racemase gene gene2461 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02462 S100141_02463 S100141_02463 S100141_02463 2262109 2262552 - putative HTH-type transcriptional regulator YsmB DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH marR-type DNA-binding domain gene gene2462 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02463 S100141_02464 S100141_02464 S100141_02464 2262716 2262940 - Spore germination protein GerE DNA-binding%3B Germination%3B Transcription%3B Transcription regulation%3B Involved in the regulation of spore formation. Directs the transcription of several genes that encode structural components of the protein coat that encases the mature spore (CotB%2C CotC%2C CotG%2C CotS%2C CotV%2C CotW%2C CotX%2C CotY and CotZ). Controls also the cgeAB and cgeCDE operons. Contains 1 HTH luxR-type DNA-binding domain gene gene2463 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02464 S100141_02465 S100141_02465 S100141_02465 2263116 2263814 - putative oxidoreductase Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family gene gene2464 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02465 S100141_02466 S100141_02466 S100141_02466 2263832 2264302 - uncharacterized protein KEGG: bli:BL00319 acyl-CoA thioester hydrolase%3B Thiolester hydrolases gene gene2465 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02466 S100141_02467 S100141_02467 sdhB sdhB 2264365 2265129 - Succinate dehydrogenase (quinone) 2Fe-2S%3B 3Fe-4S%3B 4Fe-4S%3B Electron transport%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase%3B Transport%3B Tricarboxylic acid cycle%3B Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family%3B Contains 1 4Fe-4S ferredoxin-type domain%3B KEGG: bsu:BSU28430 succinate dehydrogenase / fumarate reductase%2C iron-sulfur subunit%3B overlaps another CDS with the same product name gene gene2466 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02467 S100141_02468 S100141_02468 sdhA sdhA 2265126 2266889 - Succinate dehydrogenase (quinone) Cell membrane%3B Electron transport%3B FAD%3B Flavoprotein%3B Membrane%3B Oxidoreductase%3B Transport%3B Tricarboxylic acid cycle%3B Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily%3B KEGG: bsu:BSU28440 succinate dehydrogenase / fumarate reductase%2C flavoprotein subunit%3B overlaps another CDS with the same product name gene gene2467 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02468 S100141_02469 S100141_02469 S100141_02469 2266923 2267531 - Succinate dehydrogenase cytochrome b558 subunit Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Tricarboxylic acid cycle%3B Di-heme cytochrome of the succinate dehydrogenase complex. Belongs to the cytochrome b558 family gene gene2468 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02469 S100141_02470 S100141_02470 S100141_02470 2267833 2268276 + uncharacterized protein gene gene2469 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02470 S100141_02471 S100141_02471 S100141_02471 2268321 2269550 - Aspartate kinase Alternative initiation%3B Amino-acid biosynthesis%3B ATP-binding%3B Diaminopimelate biosynthesis%3B Kinase%3B Lysine biosynthesis%3B Nucleotide-binding%3B Repeat%3B Transferase%3B Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate%2C which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine%2C isoleucine and methionine%3B Belongs to the aspartokinase family%3B Contains 2 ACT domains%3B KEGG: vsp:VS_2582 aspartate kinase gene gene2470 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02471 S100141_02472 S100141_02472 S100141_02472 2269944 2271716 - UvrABC system protein Cytoplasm%3B DNA damage%3B DNA excision%3B DNA repair%3B Excision nuclease%3B SOS response%3B The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision%3B Belongs to the UvrC family%3B Contains 1 GIY-YIG domain%3B Contains 1 UVR domain gene gene2471 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02472 S100141_02473 S100141_02473 S100141_02473 2271859 2272173 - Thioredoxin Disulfide bond%3B Electron transport%3B Redox-active center%3B Transport%3B Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Belongs to the thioredoxin family%3B Contains 1 thioredoxin domain gene gene2472 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02473 S100141_02474 S100141_02474 S100141_02474 2272386 2273363 - Electron transfer flavoprotein subunit alpha Electron transport%3B FAD%3B Flavoprotein%3B Transport%3B The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity)%3B Belongs to the ETF alpha-subunit/FixB family gene gene2473 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02474 S100141_02475 S100141_02475 S100141_02475 2273413 2274186 - Electron transfer flavoprotein subunit beta Electron transport%3B FAD%3B Flavoprotein%3B Transport%3B The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity)%3B Belongs to the ETF beta-subunit/FixA family gene gene2474 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02475 S100141_02476 S100141_02476 S100141_02476 2274218 2274994 - Enoyl-CoA hydratase Fatty acid metabolism%3B Lipid degradation%3B Lipid metabolism%3B Lyase%3B Involved in the degradation of long-chain fatty acids. Belongs to the enoyl-CoA hydratase/isomerase family%3B KEGG: bsu:BSU28540 enoyl-CoA hydratase gene gene2475 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02476 S100141_02477 S100141_02477 S100141_02477 2274997 2275599 - Fatty acid metabolism regulator protein Cytoplasm%3B DNA-binding%3B Fatty acid metabolism%3B Lipid degradation%3B Lipid metabolism%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation%2C including acdA%2C fadA%2C fadB%2C fadE%2C fadF%2C fadG%2C fadH%2C fadM%2C fadN%2C lcfA and lcfB. Binding of FadR to DNA is specifically inhibited by long chain fatty acyl-CoA compounds of 14-20 carbon atoms in length%3B Contains 1 HTH tetR-type DNA-binding domain gene gene2476 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02477 S100141_02478 S100141_02478 S100141_02478 2275741 2277420 - Long-chain-fatty-acid--CoA ligase ATP-binding%3B Fatty acid metabolism%3B Ligase%3B Lipid metabolism%3B Nucleotide-binding%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: care:LT85_4544 long-chain acyl-CoA synthetase gene gene2477 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02478 S100141_02479 S100141_02479 S100141_02479 2277630 2278034 - UPF0719 transmembrane protein YshE Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0719 family gene gene2478 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02479 S100141_02480 S100141_02480 S100141_02480 2278053 2280410 - Endonuclease MutS2 ATP-binding%3B DNA-binding%3B Endonuclease%3B Hydrolase%3B Nuclease%3B Nucleotide-binding%3B Belongs to the DNA mismatch repair MutS family. MutS2 subfamily%3B Contains 1 Smr domain gene gene2479 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02480 S100141_02481 S100141_02481 S100141_02481 2280427 2282142 - DNA polymerase/3'-5' exonuclease PolX DNA damage%3B DNA repair%3B DNA replication%3B DNA synthesis%3B DNA-binding%3B DNA-directed DNA polymerase%3B Hydrolase%3B Magnesium%3B Manganese%3B Metal-binding%3B Multifunctional enzyme%3B Nucleotidyltransferase%3B Transferase%3B Strictly DNA-template-directed DNA polymerase%2C preferentially acting on DNA structures containing gaps from one to a few nucleotides and bearing a phosphate group at the 5' end of the downstream DNA. The fact that PolX is able to conduct filling of a single-nucleotide gap%2C allowing further sealing of the resulting nick by a DNA ligase%2C points to a putative role in base excision repair (BER) during the B. subtilis life cycle. Moreover%2C also possesses a 3'-5' exonuclease activity able to edit unpaired 3'-termini in a gapped DNA substrate and likely involved in resecting unannealed 3'-termini during DNA repair. The same PolX molecule could perform the subsequent gap-filling step. Does not display 5'-deoxyribose 5'-phosphate (dRP) lyase activity%2C as predicted by the lack of the lysine and tyrosine residues responsible for the dRP lyase activity in some other PolX members%3B In the N-terminal sectio%3B belongs to the DNA polymerase type-X family%3B In the C-terminal sectio%3B belongs to the PHP family gene gene2480 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02481 S100141_02482 S100141_02482 S100141_02482 2282286 2282822 - putative transmembrane protein YshB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2481 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02482 S100141_02483 S100141_02483 S100141_02483 2282831 2283088 - Cell division protein ZapA Cell cycle%3B Cell division%3B Coiled coil%3B Cytoplasm%3B Septation%3B Activator of cell division through the inhibition of FtsZ GTPase activity%2C therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division%3B Belongs to the ZapA family. Type 2 subfamily gene gene2482 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02483 S100141_02484 S100141_02484 rnhC rnhC 2283238 2284179 + Ribonuclease H Cytoplasm%3B Endonuclease%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nuclease%3B Endonuclease that specifically degrades the RNA of RNA- DNA hybrids%3B Belongs to the RNase HII family. RnhC subfamily%3B KEGG: bsu:BSU28620 ribonuclease HIII gene gene2483 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02484 S100141_02485 S100141_02485 S100141_02485 2284858 2285730 + hypothetical protein gene gene2484 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02485 S100141_02486 S100141_02486 S100141_02486 2285795 2286667 - putative transposase-like protein DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene2485 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02486 S100141_02487 S100141_02487 S100141_02487 2286637 2286969 - hypothetical protein gene gene2486 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02487 S100141_02488 S100141_02488 S100141_02488 2287467 2287766 + hypothetical protein gene gene2487 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02488 S100141_02489 S100141_02489 S100141_02489 2287838 2289280 + hypothetical protein gene gene2488 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02489 S100141_02490 S100141_02490 phnC phnC 2289289 2289981 + Phosphonate-transporting ATPase ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the ABC transporter superfamily. Energy- coupling factor EcfA family%3B Contains 1 ABC transporter domain%3B KEGG: maq:Maqu_3258 phosphonate transport system ATP-binding protein gene gene2489 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02490 S100141_02491 S100141_02491 S100141_02491 2289938 2290474 + hypothetical protein gene gene2490 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02491 S100141_02492 S100141_02492 S100141_02492 2290485 2291033 + hypothetical protein gene gene2491 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02492 S100141_02493 S100141_02493 pheT pheT 2291205 2293619 - Phenylalanine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B RNA-binding%3B tRNA-binding%3B Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily%3B Contains 1 B5 domain%3B Contains 1 FDX-ACB domain%3B Contains 1 tRNA-binding domain%3B KEGG: bsu:BSU28630 phenylalanyl-tRNA synthetase beta chain gene gene2492 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02493 S100141_02494 S100141_02494 pheS pheS 2293635 2294669 - Phenylalanine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily%3B KEGG: nmp:NMBB_0820 phenylalanyl-tRNA synthetase alpha chain gene gene2493 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02494 S100141_02495 S100141_02495 S100141_02495 2295031 2295777 - putative tRNA/rRNA methyltransferase YsgA Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family gene gene2494 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02495 S100141_02496 S100141_02496 S100141_02496 2295892 2296107 + Small%2C acid-soluble spore protein Sporulation%3B Belongs to the SspI family gene gene2495 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02496 S100141_02497 S100141_02497 S100141_02497 2296139 2297353 - Carbon starvation protein A like protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the CstA family gene gene2496 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02497 S100141_02498 S100141_02498 S100141_02498 2297380 2297934 - Carbon starvation protein A like protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the CstA family gene gene2497 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02498 S100141_02499 S100141_02499 S100141_02499 2298138 2298413 - hypothetical protein gene gene2498 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02499 S100141_02500 S100141_02500 abfA abfA 2298507 2300015 - Non-reducing end alpha-L-arabinofuranosidase Carbohydrate metabolism%3B Cytoplasm%3B Glycosidase%3B Hydrolase%3B Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the cleavage of terminal alpha-(1->5)-arabinofuranosyl bonds in small oligosaccharides as alpha-(1->5)-linked arabinobiose/arabinotriose%2C but does not display significant activity against linear non-substituted arabinan. It is also highly efficient in the cleavage of alpha-(1->3)-linked arabinoside of xylobiose and of the alpha-(1->3)-linked arabinoside decorations of polymeric wheat arabinoxylan. It exhibits very low activity against sugar beet arabinan%3B Belongs to the glycosyl hydrolase 51 family%3B KEGG: bli:BL00345 alpha-N-arabinofuranosidase gene gene2499 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02500 S100141_02501 S100141_02501 S100141_02501 2300051 2300893 - L-arabinose transport system permease protein AraQ Cell membrane%3B Membrane%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system for L-arabinose. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2500 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02501 S100141_02502 S100141_02502 S100141_02502 2300893 2301837 - L-arabinose transport system permease protein AraP Cell membrane%3B Membrane%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system for L-arabinose. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2501 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02502 S100141_02503 S100141_02503 S100141_02503 2301868 2303181 - putative arabinose-binding protein Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Sugar transport%3B Transport%3B Part of the binding-protein-dependent transport system for L-arabinose. Belongs to the bacterial solute-binding protein 1 family gene gene2502 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02503 S100141_02504 S100141_02504 araM araM 2303178 2304383 - sn-glycerol-1-phosphate dehydrogenase Cytoplasm%3B Lipid biosynthesis%3B Lipid metabolism%3B Metal-binding%3B NAD%3B NADP%3B Nickel%3B Oxidoreductase%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species%3B Belongs to the glycerol-1-phosphate dehydrogenase family%3B KEGG: bli:BL00349 glycerol-1-phosphate dehydrogenase (NAD(P)+) gene gene2503 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02504 S100141_02505 S100141_02505 S100141_02505 2304400 2305086 - L-ribulose-5-phosphate 4-epimerase Arabinose catabolism%3B Carbohydrate metabolism%3B Isomerase%3B Metal-binding%3B Zinc%3B Belongs to the aldolase class II family. AraD/FucA subfamily%3B KEGG: sgl:SG1415 L-ribulose-5-phosphate 4-epimerase gene gene2504 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02505 S100141_02506 S100141_02506 S100141_02506 2305102 2306760 - Ribulokinase Arabinose catabolism%3B ATP-binding%3B Carbohydrate metabolism%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the ribulokinase family%3B KEGG: bsu:BSU28790 L-ribulokinase gene gene2505 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02506 S100141_02507 S100141_02507 S100141_02507 2306808 2308289 - L-arabinose isomerase Arabinose catabolism%3B Carbohydrate metabolism%3B Isomerase%3B Manganese%3B Metal-binding%3B Catalyzes the conversion of L-arabinose to L-ribulose%3B Belongs to the arabinose isomerase family%3B KEGG: bli:BL00352 L-arabinose isomerase gene gene2506 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02507 S100141_02508 S100141_02508 S100141_02508 2308554 2309516 - Arabinan endo-1%2C5-alpha-L-arabinosidase Calcium%3B Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Metal-binding%3B Secreted%3B Signal%3B Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the internal cleavage of alpha-(1->5)-L-arabinofuranosyl residues of linear 1%2C5-alpha-L-arabinan and of branched sugar beet arabinan. It displays no activity against heavily substituted arabinans or a range of other polysaccharides (larch wood arabinogalactan%2C wheat arabinoxylan and p-nitrophenyl-alpha-L- arabinofuranoside). The enzyme activity is progressively reduced as alpha-(1->5)-chains become shorter or more highly substituted%3B Belongs to the glycosyl hydrolase 43 family%3B KEGG: bli:BL00353 arabinan endo-1%2C5-alpha-L-arabinosidase gene gene2507 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02508 S100141_02509 S100141_02509 S100141_02509 2309674 2310759 - Cellulase Aminopeptidase%3B Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Putative aminopeptidase. Belongs to the peptidase M42 family%3B KEGG: bsu:BSU28820 endoglucanase gene gene2508 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02509 S100141_02510 S100141_02510 S100141_02510 2310933 2311334 + Sigma-w pathway protein YsdB Membrane%3B Transmembrane%3B Transmembrane helix%3B May mediate a negative feedback loop that down-regulates the expression of the sigma-W regulon following the activation of sigma-W in response to conditions of cell envelope stress. Might interact with and inhibit the activity of the protease PrsW%2C or could bind to the anti-sigma-W factor RsiW and thereby protect it from PrsW-mediated cleavage gene gene2509 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02510 S100141_02511 S100141_02511 S100141_02511 2311351 2311593 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2510 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02511 S100141_02512 S100141_02512 S100141_02512 2311731 2312090 - 50S ribosomal protein L20%2C chloroplastic Chloroplast%3B Plastid%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA editing%3B RNA-binding%3B rRNA-binding%3B Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit%3B Belongs to the ribosomal protein L20P family gene gene2511 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02512 S100141_02513 S100141_02513 S100141_02513 2312124 2312324 - 50S ribosomal protein L35 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L35P family gene gene2512 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02513 S100141_02514 S100141_02514 S100141_02514 2312342 2312977 - Translation initiation factor IF-3 Cytoplasm%3B Initiation factor%3B Protein biosynthesis%3B IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits%2C thus enhancing the availability of 30S subunits on which protein synthesis initiation begins%3B Belongs to the IF-3 family gene gene2513 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02514 S100141_02515 S100141_02515 S100141_02515 2313196 2313879 - Antiholin-like protein LrgB Cell membrane%3B Cytolysis%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Inhibits the expression or activity of extracellular murein hydrolases by interacting%2C possibly with LrgA%2C with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD)%2C possibly triggering PCD in response to antibiotics and environmental stresses%3B Belongs to the CidB/LrgB family. LrgB subfamily gene gene2514 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02515 S100141_02516 S100141_02516 S100141_02516 2313903 2314316 - Antiholin-like protein LrgA Cell membrane%3B Cytolysis%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Inhibits the expression or activity of extracellular murein hydrolases by interacting%2C possibly with LrgB%2C with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD)%2C possibly triggering PCD in response to antibiotics and environmental stresses%3B Belongs to the CidA/LrgA family. LrgA subfamily gene gene2515 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02516 S100141_02517 S100141_02517 phoD phoD 2314553 2316109 + Alkaline phosphatase Hydrolase%3B Signal%3B Stress response%3B Belongs to the PhoD family%3B KEGG: bli:BL05301 alkaline phosphatase D gene gene2516 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02517 S100141_02518 S100141_02518 S100141_02518 2316165 2316887 - Chemotaxis response regulator protein-glutamate methylesterase Chemotaxis%3B Cytoplasm%3B Hydrolase%3B Phosphoprotein%3B Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene2517 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02518 S100141_02519 S100141_02519 lytS lytS 2316862 2318646 - Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism. Contains 1 GAF domain%3B Contains 1 histidine kinase domain%3B KEGG: bli:BL00380 two-component system%2C LytT family%2C sensor histidine kinase LytS gene gene2518 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02519 S100141_02520 S100141_02520 S100141_02520 2318806 2319033 - hypothetical protein gene gene2519 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02520 S100141_02521 S100141_02521 S100141_02521 2319286 2320098 + Putative uncharacterized hydrolase YsaA Hydrolase%3B Belongs to the HAD-like hydrolase superfamily gene gene2520 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02521 S100141_02522 S100141_02522 S100141_02522 2320130 2322061 - Threonine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B Zinc%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: bli:BL00382 threonyl-tRNA synthetase gene gene2521 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02522 S100141_02523 S100141_02523 S100141_02523 2322405 2323247 - uncharacterized protein gene gene2522 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02523 S100141_02524 S100141_02524 S100141_02524 2323324 2323953 - TVP38/TMEM64 family membrane protein YtxB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the TVP38/TMEM64 family gene gene2523 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02524 S100141_02525 S100141_02525 S100141_02525 2323992 2324270 - Primosomal protein DnaI ATP-binding%3B DNA replication%3B Nucleotide-binding%3B Primosome. gene gene2524 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02525 S100141_02526 S100141_02526 S100141_02526 2324312 2324926 - Primosomal protein DnaI ATP-binding%3B DNA replication%3B Nucleotide-binding%3B Primosome. gene gene2525 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02526 S100141_02527 S100141_02527 S100141_02527 2324941 2326365 - Replication initiation and membrane attachment protein ATP-binding%3B DNA replication%3B DNA-binding%3B Nucleotide-binding%3B Primosome. gene gene2526 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02527 S100141_02528 S100141_02528 S100141_02528 2326482 2326940 - Transcriptional repressor NrdR ATP-binding%3B DNA-binding%3B Metal-binding%3B Nucleotide-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Zinc%3B Zinc-finger%3B Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes%3B Belongs to the NrdR family%3B Contains 1 ATP-cone domain gene gene2527 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02528 S100141_02529 S100141_02529 S100141_02529 2326956 2327348 - hypothetical protein gene gene2528 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02529 S100141_02530 S100141_02530 speD speD 2327530 2327916 - Adenosylmethionine decarboxylase Autocatalytic cleavage%3B Decarboxylase%3B Lyase%3B Polyamine biosynthesis%3B Pyruvate%3B S-adenosyl-L-methionine%3B Schiff base%3B Spermidine biosynthesis%3B Zymogen%3B Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet)%2C the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine%3B Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily%3B KEGG: nis:NIS_1526 S-adenosylmethionine decarboxylase gene gene2529 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02530 S100141_02531 S100141_02531 gapA gapA 2328153 2329175 - Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) Cytoplasm%3B Glycolysis%3B NAD%3B Nucleotide-binding%3B Oxidoreductase%3B Involved in the glycolysis. Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1%2C3- bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue%2C and this hemiacetal intermediate is then oxidized to a thioester%2C with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD%2C and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG%3B Belongs to the glyceraldehyde-3-phosphate dehydrogenase family%3B KEGG: eco:b1779 glyceraldehyde 3-phosphate dehydrogenase gene gene2530 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02531 S100141_02532 S100141_02532 S100141_02532 2329426 2330910 + Pectin lyase Lyase%3B Belongs to the polysaccharide lyase 1 family%3B KEGG: bli:BL00361 pectin lyase gene gene2531 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02532 S100141_02533 S100141_02533 coaE coaE 2330937 2331542 - Dephospho-CoA kinase ATP-binding%3B Coenzyme A biosynthesis%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A%3B Belongs to the CoaE family%3B Contains 1 DPCK (dephospho-CoA kinase) domain%3B KEGG: ppr:PBPRA3204 dephospho-CoA kinase gene gene2532 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02533 S100141_02534 S100141_02534 S100141_02534 2331560 2332192 - Putative membrane protein YtaF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2533 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02534 S100141_02535 S100141_02535 mutM mutM 2332413 2333240 - DNA-formamidopyrimidine glycosylase DNA damage%3B DNA repair%3B DNA-binding%3B Glycosidase%3B Hydrolase%3B Lyase%3B Metal-binding%3B Multifunctional enzyme%3B Zinc%3B Zinc-finger%3B Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines%2C such as 7%2C8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates%3B Belongs to the FPG family%3B Contains 1 FPG-type zinc finger%3B KEGG: dma:DMR_16970 formamidopyrimidine-DNA glycosylase gene gene2534 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02535 S100141_02536 S100141_02536 S100141_02536 2333259 2335898 - DNA-directed DNA polymerase DNA damage%3B DNA repair%3B DNA replication%3B DNA-binding%3B DNA-directed DNA polymerase%3B Exonuclease%3B Hydrolase%3B Nuclease%3B Nucleotidyltransferase%3B Transferase%3B In addition to polymerase activity%2C this DNA polymerase exhibits 3' to 5' and 5' to 3' exonuclease activity%3B Belongs to the DNA polymerase type-A family%3B Contains 1 3'-5' exonuclease domain%3B Contains 1 5'-3' exonuclease domain%3B KEGG: bsu:BSU29090 DNA polymerase I gene gene2535 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02536 S100141_02537 S100141_02537 phoR phoR 2336154 2337899 - Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphate transport%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Two-component regulatory system%3B Member of the two-component regulatory system PhoP/PhoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoP in response to environmental signals. Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bsu:BSU29100 two-component system%2C OmpR family%2C phosphate regulon sensor histidine kinase PhoR gene gene2536 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02537 S100141_02538 S100141_02538 S100141_02538 2337892 2338614 - Phosphate regulon transcriptional regulatory protein Activator%3B Cytoplasm%3B DNA-binding%3B Phosphate transport%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Transport%3B Two-component regulatory system%3B This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited (By similarity)%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2537 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02538 S100141_02539 S100141_02539 S100141_02539 2338957 2339895 - Malate dehydrogenase NAD%3B Oxidoreductase%3B Phosphoprotein%3B Tricarboxylic acid cycle%3B Catalyzes the reversible oxidation of malate to oxaloacetate%3B Belongs to the LDH/MDH superfamily. MDH type 3 family%3B KEGG: bli:BL00397 malate dehydrogenase gene gene2538 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02539 S100141_02540 S100141_02540 idh1 idh1 2339944 2341260 - Isocitrate dehydrogenase (NADP(+)) Acetylation%3B Glyoxylate bypass%3B Magnesium%3B Manganese%3B Metal-binding%3B NADP%3B Oxidoreductase%3B Phosphoprotein%3B Tricarboxylic acid cycle%3B Belongs to the isocitrate and isopropylmalate dehydrogenases family%3B KEGG: bld:BLi03061 isocitrate dehydrogenase gene gene2539 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02540 S100141_02541 S100141_02541 S100141_02541 2341383 2342501 - Citrate (Si)-synthase Allosteric enzyme%3B Phosphoprotein%3B Transferase%3B Tricarboxylic acid cycle%3B Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect. Belongs to the citrate synthase family%3B KEGG: bsu:BSU29140 citrate synthase gene gene2540 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02541 S100141_02542 S100141_02542 S100141_02542 2342924 2343388 - UPF0756 membrane protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0756 family gene gene2541 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02542 S100141_02543 S100141_02543 S100141_02543 2343490 2344605 + UPF0118 membrane protein YtvI Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0118 (PerM) family gene gene2542 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02543 S100141_02544 S100141_02544 S100141_02544 2344648 2345034 - UPF0716 protein YtzA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0716 (FxsA) family gene gene2543 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02544 S100141_02545 S100141_02545 S100141_02545 2345347 2347104 - Pyruvate kinase ATP-binding%3B Cytoplasm%3B Glycolysis%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Potassium%3B Pyruvate%3B Transferase%3B Belongs to the pyruvate kinase family%3B KEGG: eco:b1676 pyruvate kinase gene gene2544 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02545 S100141_02546 S100141_02546 pfkA pfkA 2347129 2348088 - 6-phosphofructokinase Allosteric enzyme%3B ATP-binding%3B Cytoplasm%3B Glycolysis%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Transferase%3B Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1%2C6-bisphosphate by ATP%2C the first committing step of glycolysis%3B Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily%3B KEGG: eco:b3916 6-phosphofructokinase 1 gene gene2545 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02546 S100141_02547 S100141_02547 accA accA 2348331 2349308 - Acetyl-CoA carboxylase ATP-binding%3B Cytoplasm%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Ligase%3B Lipid biosynthesis%3B Lipid metabolism%3B Nucleotide-binding%3B Component of the acetyl coenzyme A carboxylase (ACC) complex. First%2C biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA%3B Belongs to the AccA family%3B KEGG: bli:BL00404 acetyl-CoA carboxylase carboxyl transferase subunit alpha%3B overlaps another CDS with the same product name gene gene2546 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02547 S100141_02548 S100141_02548 accD accD 2349293 2350168 - Acetyl-CoA carboxylase ATP-binding%3B Cytoplasm%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Ligase%3B Lipid biosynthesis%3B Lipid metabolism%3B Metal-binding%3B Nucleotide-binding%3B Zinc%3B Zinc-finger%3B Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA%3B Belongs to the AccD/PCCB family%3B KEGG: bli:BL00405 acetyl-CoA carboxylase carboxyl transferase subunit beta%3B overlaps another CDS with the same product name gene gene2547 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02548 S100141_02549 S100141_02549 sfcA sfcA 2350529 2351764 - Malate dehydrogenase (oxaloacetate-decarboxylating) Metal-binding%3B NAD%3B Oxidoreductase%3B Belongs to the malic enzymes family%3B KEGG: bsu:BSU29220 malate dehydrogenase (oxaloacetate-decarboxylating) gene gene2548 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02549 S100141_02550 S100141_02550 dnaE dnaE 2351907 2355251 - DNA-directed DNA polymerase Cytoplasm%3B DNA replication%3B DNA-directed DNA polymerase%3B Nucleotidyltransferase%3B Transferase%3B DNA polymerase III is a complex%2C multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase (By similarity)%3B Belongs to the DNA polymerase type-C family. DnaE subfamily%3B KEGG: bsu:BSU29230 DNA polymerase III subunit alpha gene gene2549 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02550 S100141_02551 S100141_02551 S100141_02551 2355391 2355732 + Sporulation membrane protein YtrH Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Involved in sporulation. May contribute to cortex formation or stability gene gene2550 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02551 S100141_02552 S100141_02552 S100141_02552 2355729 2356232 + Sporulation membrane protein YtrI Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Involved in sporulation gene gene2551 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02552 S100141_02553 S100141_02553 S100141_02553 2356345 2356524 + uncharacterized protein gene gene2552 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02553 S100141_02554 S100141_02554 S100141_02554 2356640 2357584 - Bifunctional oligoribonuclease and PAP phosphatase NrnA Exonuclease%3B Hydrolase%3B Nuclease%3B Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA and DNA oligonucleotides with a length of 5 nucleotides and shorter%2C with a preference for 3-mers. Directionality is controversia%3B shown to degrade 5-mers and less in a 3' to 5' direction (PubMed:17586819)%2C and 11-mers in a 5' to 3' direction (PubMed:21087930). Converts 3'(2')- phosphoadenosine 5'-phosphate (PAP) to AMP%3B Belongs to the NrnA oligoribonuclease family gene gene2553 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02554 S100141_02555 S100141_02555 S100141_02555 2357731 2358033 + putative membrane protein YtpI Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2554 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02555 S100141_02556 S100141_02556 guaB guaB 2358062 2359393 - IMP dehydrogenase CBS domain%3B Repeat%3B Contains 2 CBS domains%3B KEGG: afu:AF_1259 IMP dehydrogenase gene gene2555 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02556 S100141_02557 S100141_02557 S100141_02557 2359477 2360034 - Negative transcription regulator PadR Cytoplasm%3B Repressor%3B Transcription%3B Transcription regulation%3B Negative transcriptional regulator of padC phenolic acid decarboxylase gene gene2556 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02557 S100141_02558 S100141_02558 S100141_02558 2360151 2360837 - UPF0173 metal-dependent hydrolase Hydrolase%3B Belongs to the UPF0173 family gene gene2557 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02558 S100141_02559 S100141_02559 S100141_02559 2360872 2361681 - 3-oxoacyl-[acyl-carrier-protein] reductase Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: blh:BaLi_c31620 3-oxoacyl-(acyl-carrier protein) reductase gene gene2558 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02559 S100141_02560 S100141_02560 S100141_02560 2361812 2361955 - hypothetical protein gene gene2559 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02560 S100141_02561 S100141_02561 argH argH 2362030 2362674 - Argininosuccinate lyase Amino-acid biosynthesis%3B Arginine biosynthesis%3B Cytoplasm%3B Lyase%3B Belongs to the lyase 1 family. Argininosuccinate lyase subfamily%3B KEGG: buc:BU051 argininosuccinate lyase gene gene2560 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02561 S100141_02562 S100141_02562 S100141_02562 2362692 2363408 - Argininosuccinate lyase Amino-acid biosynthesis%3B Arginine biosynthesis%3B Cytoplasm%3B Lyase%3B Belongs to the lyase 1 family. Argininosuccinate lyase subfamily%3B KEGG: bam:Bamb_6457 argininosuccinate lyase gene gene2561 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02562 S100141_02563 S100141_02563 argG argG 2363405 2364616 - Argininosuccinate synthase Amino-acid biosynthesis%3B Arginine biosynthesis%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Belongs to the argininosuccinate synthase family. Type 1 subfamily%3B KEGG: bli:BL00417 argininosuccinate synthase gene gene2562 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02563 S100141_02564 S100141_02564 S100141_02564 2364809 2365327 - Molybdenum cofactor biosynthesis protein Molybdenum cofactor biosynthesis%3B May be involved in the biosynthesis of molybdopterin%3B Belongs to the MoaB/Mog family gene gene2563 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02564 S100141_02565 S100141_02565 ackA ackA 2365426 2366613 - Acetate kinase ATP-binding%3B Cytoplasm%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Transferase%3B Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction%3B Belongs to the acetokinase family%3B KEGG: tau:Tola_1703 acetate kinase gene gene2564 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02565 S100141_02566 S100141_02566 S100141_02566 2366843 2367829 - Site-specific DNA-methyltransferase (adenine-specific) To type I restriction system adenine methylases%3B KEGG: bli:BL00420 site-specific DNA-methyltransferase (adenine-specific) gene gene2565 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02566 S100141_02567 S100141_02567 S100141_02567 2367915 2368418 - Peroxiredoxin Antioxidant%3B Oxidoreductase%3B Peroxidase%3B Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)%3B Belongs to the AhpC/TSA family. Tpx subfamily%3B Contains 1 thioredoxin domain%3B KEGG: pbc:CD58_15555 thiol peroxidase%2C atypical 2-Cys peroxiredoxin gene gene2566 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02567 S100141_02568 S100141_02568 S100141_02568 2368564 2369022 - putative spore protein YtfJ Sporulation. gene gene2567 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02568 S100141_02569 S100141_02569 S100141_02569 2369035 2369718 - uncharacterized protein Signal. gene gene2568 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02569 S100141_02570 S100141_02570 S100141_02570 2369840 2370358 - putative membrane protein YteJ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Contains 1 RDD domain gene gene2569 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02570 S100141_02571 S100141_02571 sppA sppA 2370374 2371381 - Putative signal peptide peptidase SppA Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Serine protease%3B Transmembrane%3B Transmembrane helix%3B Digestion of cleaved signal peptides (By similarity). Required for efficient processing of precursors under conditions of hyper-secretion. Has a preference for leucine-rich substrate peptides%3B Belongs to the peptidase S49 family%3B KEGG: bsu:BSU29530 protease IV%3B Serine endopeptidases gene gene2570 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02571 S100141_02572 S100141_02572 S100141_02572 2371574 2372371 + NAD(+) kinase ATP-binding%3B Cytoplasm%3B Kinase%3B NAD%3B NADP%3B Nucleotide-binding%3B Transferase%3B Involved in the regulation of the intracellular balance of NAD and NADP%2C and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP%3B Belongs to the NAD kinase family%3B KEGG: bli:BL00367 NAD+ kinase gene gene2571 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02572 S100141_02573 S100141_02573 S100141_02573 2372433 2373068 - Putative efflux system component YhbJ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene2572 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02573 S100141_02574 S100141_02574 S100141_02574 2373071 2374693 - putative MFS-type transporter YubD Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene2573 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02574 S100141_02575 S100141_02575 S100141_02575 2374831 2375259 - putative HTH-type transcriptional regulator YxaD DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH marR-type DNA-binding domain gene gene2574 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02575 S100141_02576 S100141_02576 S100141_02576 2375285 2376874 - Acetate--CoA ligase ATP-binding%3B Ligase%3B Nucleotide-binding%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bsu:BSU29560 acetyl-CoA synthetase gene gene2575 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02576 S100141_02577 S100141_02577 S100141_02577 2377017 2377229 - Small%2C acid-soluble spore protein DNA-binding%3B Sporulation%3B SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. Belongs to the alpha/beta-type SASP family gene gene2576 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02577 S100141_02578 S100141_02578 S100141_02578 2377341 2378546 - putative tRNA sulfurtransferase ATP-binding%3B Cytoplasm%3B Nucleotide-binding%3B RNA-binding%3B Thiamine biosynthesis%3B Transferase%3B tRNA-binding%3B Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs%2C which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS%2C forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole%2C in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS%3B Belongs to the ThiI family%3B Contains 1 THUMP domain gene gene2577 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02578 S100141_02579 S100141_02579 S100141_02579 2378554 2379699 - Cysteine desulfurase Iron%3B Iron-sulfur%3B Metal-binding%3B Pyridoxal phosphate%3B Transferase%3B Catalyzes the removal of elemental sulfur from cysteine to produce alanine%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily%3B KEGG: bsu:BSU29590 cysteine desulfurase gene gene2578 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02579 S100141_02580 S100141_02580 S100141_02580 2379893 2381230 + Branched-chain amino acid transport system carrier protein BrnQ Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Component of the transport system for branched-chain amino acids (leucine%2C isoleucine and valine) Which is coupled to a proton motive force%3B Belongs to the branched chain amino acid transporter family gene gene2579 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02580 S100141_02581 S100141_02581 S100141_02581 2381399 2381731 + hypothetical protein gene gene2580 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02581 S100141_02582 S100141_02582 S100141_02582 2381701 2382081 + hypothetical protein gene gene2581 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02582 S100141_02583 S100141_02583 S100141_02583 2382039 2382560 + Putative transposase InsK for insertion sequence element IS150 DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Involved in the transposition of the insertion sequence IS150. Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene2582 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02583 S100141_02584 S100141_02584 S100141_02584 2382621 2384315 - Septation ring formation regulator EzrA Cell cycle%3B Cell division%3B Cell membrane%3B Coiled coil%3B Membrane%3B Septation%3B Transmembrane%3B Transmembrane helix%3B Negative regulator of FtsZ ring formatio%3B modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization%3B Belongs to the EzrA family gene gene2583 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02584 S100141_02585 S100141_02585 S100141_02585 2384504 2385316 + Histidinol-phosphatase Amino-acid biosynthesis%3B Histidine biosynthesis%3B Hydrolase%3B Belongs to the PHP hydrolase family. HisK subfamily%3B KEGG: bsu:BSU29620 histidinol-phosphatase (PHP family) gene gene2584 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02585 S100141_02586 S100141_02586 S100141_02586 2385309 2385947 - putative HTH-type transcriptional regulator YttP DNA-binding%3B Repressor%3B Stress response%3B Transcription%3B Transcription regulation%3B Contains 1 HTH tetR-type DNA-binding domain gene gene2585 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02586 S100141_02587 S100141_02587 S100141_02587 2386076 2386570 + Protein YtsP Belongs to the free Met sulfoxide reductase family gene gene2586 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02587 S100141_02588 S100141_02588 S100141_02588 2386584 2388284 - Diguanylate cyclase Contains 1 GGDEF domain%3B KEGG: yen:YE2425 diguanylate cyclase gene gene2587 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02588 S100141_02589 S100141_02589 S100141_02589 2388614 2389216 + 30S ribosomal protein S4 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B One of the primary rRNA binding proteins%2C it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit%3B With S5 and S12 plays an important role in translational accuracy%3B Belongs to the ribosomal protein S4P family%3B Contains 1 S4 RNA-binding domain gene gene2588 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02589 S100141_02590 S100141_02590 S100141_02590 2389252 2389440 - hypothetical protein gene gene2589 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02590 S100141_02591 S100141_02591 S100141_02591 2389518 2389748 + hypothetical protein gene gene2590 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02591 S100141_02592 S100141_02592 S100141_02592 2390037 2390474 - Inner membrane protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B To E. coli YhaI gene gene2591 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02592 S100141_02593 S100141_02593 S100141_02593 2390970 2391740 - UPF0173 protein YddR Hydrolase%3B Belongs to the UPF0173 family gene gene2592 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02593 S100141_02594 S100141_02594 S100141_02594 2391864 2392283 + Proline dehydrogenase transcriptional activator Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Transcriptional activator of the putA gene in response to proline. Contains 1 HTH asnC-type DNA-binding domain gene gene2593 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02594 S100141_02595 S100141_02595 S100141_02595 2392334 2392480 - hypothetical protein gene gene2594 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02595 S100141_02596 S100141_02596 yarS yarS 2392613 2393878 - Tyrosine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B RNA-binding%3B Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)%3B Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily%3B Contains 1 S4 RNA-binding domain%3B KEGG: bli:BL00439 tyrosyl-tRNA synthetase gene gene2595 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02596 S100141_02597 S100141_02597 S100141_02597 2394220 2395938 - Acetate--CoA ligase Acetylation%3B ATP-binding%3B Ligase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Catalyzes the conversion of acetate into acetyl-CoA (AcCoA)%2C an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction%2C AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction%2C it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA%2C forming the product AcCoA (By similarity). Has a role in growth and sporulation on acetate%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bsu:BSU29680 acetyl-CoA synthetase gene gene2596 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02597 S100141_02598 S100141_02598 acuA acuA 2396094 2396726 + Acetoin utilization protein AcuA Acetoin catabolism%3B Acyltransferase%3B Transferase%3B Part of the acuABC operon%2C which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bsu:BSU29690 acetoin utilization protein AcuA%3B Transferring groups other than amino-acyl groups gene gene2597 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02598 S100141_02599 S100141_02599 S100141_02599 2396748 2397392 + Acetoin utilization protein AcuB Acetoin catabolism%3B CBS domain%3B Repeat%3B Sporulation%3B Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source. Contains 2 CBS domains gene gene2598 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02599 S100141_02600 S100141_02600 S100141_02600 2397389 2398549 + Acetoin utilization protein AcuC Acetoin catabolism%3B Sporulation%3B Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source. Belongs to the histone deacetylase family gene gene2599 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02600 S100141_02601 S100141_02601 S100141_02601 2398611 2399300 - putative 24.6 kDa protein in ccpA 3'region Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B May be involved in some transport function. Belongs to the MotB family%3B Contains 1 OmpA-like domain gene gene2600 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02601 S100141_02602 S100141_02602 S100141_02602 2399290 2400108 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B May be involved in some transport function. Belongs to the MotA family gene gene2601 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02602 S100141_02603 S100141_02603 S100141_02603 2400204 2401205 - Catabolite control protein Activator%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA)%2C which ensures optimal energy usage under diverse conditions. Interacts with either P-Ser-HPr or P-Ser-Crh%2C leading to the formation of a complex that binds to DNA at the catabolite-response elements (cre). Binding to DNA allows activation or repression of many different genes and operons%3B Contains 1 HTH lacI-type DNA-binding domain gene gene2602 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02603 S100141_02604 S100141_02604 aroG aroG 2401521 2402597 - 3-deoxy-7-phosphoheptulonate synthase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Isomerase%3B Multifunctional enzyme%3B Phosphoprotein%3B Transferase%3B Belongs to the class-I DAHP synthase family%3B Contains 1 chorismate mutase domain%3B KEGG: bsu:BSU29750 3-deoxy-7-phosphoheptulonate synthase / chorismate mutase gene gene2603 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02604 S100141_02605 S100141_02605 S100141_02605 2402708 2402866 - hypothetical protein gene gene2604 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02605 S100141_02606 S100141_02606 S100141_02606 2402808 2403257 - UPF0134 protein Belongs to the UPF0134 family gene gene2605 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02606 S100141_02607 S100141_02607 S100141_02607 2403407 2403733 - uncharacterized protein gene gene2606 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02607 S100141_02608 S100141_02608 S100141_02608 2403754 2404170 - uncharacterized protein To C. plantagineum desiccation-related protein clone PCC3-06 gene gene2607 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02608 S100141_02609 S100141_02609 S100141_02609 2404174 2404596 - UPF0478 protein YtxG Coiled coil%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0478 family gene gene2608 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02609 S100141_02610 S100141_02610 murC murC 2404763 2406061 - UDP-N-acetylmuramate--L-alanine ligase ATP-binding%3B Cell cycle%3B Cell division%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Peptidoglycan synthesis%3B Cell wall formation%3B Belongs to the MurCDEF family%3B KEGG: bsu:BSU29790 UDP-N-acetylmuramate--alanine ligase gene gene2609 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02610 S100141_02611 S100141_02611 S100141_02611 2406327 2409233 - DNA translocase SftA ATP-binding%3B Cell cycle%3B Cell division%3B Chromosome partition%3B Cytoplasm%3B DNA-binding%3B Nucleotide-binding%3B Required for the accurate completion of chromosome partitioning%2C in part by promoting efficient resolution of chromosome dimers%2C before the formation of the division septum. Binds to DNA in a non-specific manner. Shows ATPase activity. Not required for cytokinesis%3B Belongs to the FtsK/SpoIIIE/SftA family%3B Contains 1 FtsK domain gene gene2610 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02611 S100141_02612 S100141_02612 S100141_02612 2409418 2410023 - Putative tRNA-binding protein YtpR RNA-binding%3B tRNA-binding%3B Contains 1 tRNA-binding domain gene gene2611 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02612 S100141_02613 S100141_02613 S100141_02613 2410042 2410851 - UPF0354 protein Belongs to the UPF0354 family gene gene2612 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02613 S100141_02614 S100141_02614 S100141_02614 2410871 2411191 - Thioredoxin-like protein YtpP Disulfide bond%3B Redox-active center%3B Contains 1 thioredoxin domain gene gene2613 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02614 S100141_02615 S100141_02615 S100141_02615 2411481 2411927 + uncharacterized protein gene gene2614 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02615 S100141_02616 S100141_02616 pepA pepA 2411980 2413053 - Glutamyl aminopeptidase Aminopeptidase%3B Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Belongs to the peptidase M42 family%3B KEGG: cml:BN424_1132 glutamyl aminopeptidase gene gene2615 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02616 S100141_02617 S100141_02617 S100141_02617 2413190 2413504 + uncharacterized protein gene gene2616 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02617 S100141_02618 S100141_02618 S100141_02618 2413541 2415238 - Malate dehydrogenase (oxaloacetate-decarboxylating) Metal-binding%3B NAD%3B Oxidoreductase%3B Belongs to the malic enzymes family%3B KEGG: bli:BL00044 malate dehydrogenase (oxaloacetate-decarboxylating) gene gene2617 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02618 S100141_02619 S100141_02619 S100141_02619 2415311 2416156 - putative quorum-quenching lactonase YtnP Hydrolase%3B Metal-binding%3B Phosphoprotein%3B Zinc%3B Probable hydrolase that is able to inhibit the signaling pathway required for the streptomycin production and development of aerial mycelium in S. griseus. Thus%2C serves as a defensive strategy against competing bacteria. The putative target for YtnP may be a gamma-butyrolactone termed A factor%2C which is the quorum- sensing signaling molecule that positively regulates streptomycin production and development of aerial hyphae in S. griseus%3B Belongs to the metallo-beta-lactamase superfamily gene gene2618 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02619 S100141_02620 S100141_02620 trmB trmB 2416252 2416893 - tRNA (guanine(46)-N(7))-methyltransferase Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B tRNA processing%3B Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family%3B KEGG: bsu:BSU29900 tRNA (guanine-N7-)-methyltransferase gene gene2619 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02620 S100141_02621 S100141_02621 S100141_02621 2417074 2417352 + uncharacterized protein gene gene2620 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02621 S100141_02622 S100141_02622 S100141_02622 2417347 2418150 - Putative phosphotransferase YtmP ATP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the aminoglycoside phosphotransferase family gene gene2621 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02622 S100141_02623 S100141_02623 S100141_02623 2418339 2420039 - Pullulanase Glycosidase%3B Hydrolase%3B Belongs to the glycosyl hydrolase 13 family%3B KEGG: bli:BL00040 pullulanase%3B overlaps another CDS with the same product name gene gene2622 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02623 S100141_02624 S100141_02624 S100141_02624 2420036 2420470 - Pullulanase KEGG: bli:BL00040 pullulanase%3B overlaps another CDS with the same product name gene gene2623 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02624 S100141_02625 S100141_02625 cerK cerK 2420497 2421417 - Ceramide kinase ATP-binding%3B Kinase%3B Lipid biosynthesis%3B Lipid metabolism%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG). In fact%2C is not able to exhibit diacylglycerol kinase activity in vitro. Belongs to the diacylglycerol/lipid kinase family%3B Contains 1 DAGKc domain%3B KEGG: ppp:PHYPADRAFT_158844 ceramide kinase gene gene2624 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02625 S100141_02626 S100141_02626 S100141_02626 2421470 2422411 - uncharacterized protein Coiled coil. gene gene2625 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02626 S100141_02627 S100141_02627 ligT ligT 2422395 2423000 - RNA 2'%2C3'-cyclic phosphodiesterase Hydrolase%3B Hydrolyzes RNA 2'%2C3'-cyclic phosphodiester to an RNA 2'- phosphomonoester%3B Belongs to the 2H phosphoesterase superfamily. ThpR family%3B KEGG: bli:BL00037 2'-5' RNA ligase%3B Forming phosphoric ester bonds gene gene2626 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02627 S100141_02628 S100141_02628 cysK cysK 2423138 2424070 + Cysteine synthase Amino-acid biosynthesis%3B Cysteine biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Belongs to the cysteine synthase/cystathionine beta- synthase family%3B KEGG: bli:BL00070 cysteine synthase A gene gene2627 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02628 S100141_02629 S100141_02629 S100141_02629 2424874 2425011 - hypothetical protein gene gene2628 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02629 S100141_02630 S100141_02630 dapE dapE 2425028 2426419 - Succinyl-diaminopimelate desuccinylase Dipeptidase%3B Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Zinc%3B Belongs to the peptidase M20A family%3B KEGG: bli:BL00035 succinyl-diaminopimelate desuccinylase gene gene2629 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02630 S100141_02631 S100141_02631 S100141_02631 2426527 2427834 + Guanine/hypoxanthine permease PbuO Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the uptake of the purine bases hypoxanthine and guanine. May work at purine concentrations higher than 100 uM%3B Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2. A. 1. 40) subfamily gene gene2630 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02631 S100141_02632 S100141_02632 S100141_02632 2428167 2428388 + putative HTH-type transcriptional regulator YtzE DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH deoR-type DNA-binding domain gene gene2631 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02632 S100141_02633 S100141_02633 rsuA rsuA 2428509 2429231 - 16S rRNA pseudouridine(516) synthase Isomerase%3B RNA-binding%3B Belongs to the pseudouridine synthase RsuA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: par:Psyc_0024 16S rRNA pseudouridine516 synthase gene gene2632 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02633 S100141_02634 S100141_02634 S100141_02634 2429271 2430914 - putative cell division protein YtgP Cell cycle%3B Cell division%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B May play a role in cell division%2C although it is not essential for growth%3B Belongs to the polysaccharide synthase family gene gene2633 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02634 S100141_02635 S100141_02635 S100141_02635 2431134 2432408 + uncharacterized protein gene gene2634 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02635 S100141_02636 S100141_02636 S100141_02636 2432636 2434174 + Glycine betaine transporter OpuD Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B High-affinity uptake of glycine betaine. Does not mediate either carnitine or choline uptake%3B Belongs to the BCCT transporter (TC 2. A. 15) family gene gene2635 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02636 S100141_02637 S100141_02637 S100141_02637 2434210 2434392 - Sporulation protein cse60 Sporulation. gene gene2636 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02637 S100141_02638 S100141_02638 S100141_02638 2434558 2434884 - Hydroxyacylglutathione hydrolase Contains 1 rhodanese domain%3B KEGG: mma:MM_2931 hydroxyacylglutathione hydrolase gene gene2637 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02638 S100141_02639 S100141_02639 S100141_02639 2434964 2435098 - hypothetical protein gene gene2638 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02639 S100141_02640 S100141_02640 S100141_02640 2435095 2435901 - Response regulator aspartate phosphatase Hydrolase%3B Protein phosphatase%3B Repeat%3B TPR repeat%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bha:BH4014 response regulator aspartate phosphatase G%3B Acting on ester bonds gene gene2639 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02640 S100141_02641 S100141_02641 S100141_02641 2436308 2436667 - hypothetical protein gene gene2640 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02641 S100141_02642 S100141_02642 S100141_02642 2436704 2437351 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2641 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02642 S100141_02643 S100141_02643 iolG iolG 2437368 2438645 - Inositol 2-dehydrogenase Oxidoreductase%3B Signal%3B May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: rhi:NGR_b04530 myo-inositol 2-dehydrogenase / D-chiro-inositol 1-dehydrogenase gene gene2642 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02643 S100141_02644 S100141_02644 S100141_02644 2438665 2439159 - Putative lipoprotein YteS Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls gene gene2643 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02644 S100141_02645 S100141_02645 S100141_02645 2439156 2440277 - Unsaturated rhamnogalacturonyl hydrolase Cytoplasm%3B Glycosidase%3B Hydrolase%3B Catalyzes the hydrolysis of unsaturated rhamnogalacturonan disaccharide to yield unsaturated D- galacturonic acid and L-rhamnose. It cannot act on unsaturated glucuronyl hydrolase (UGL) substrates containing unsaturated D- glucuronic acid at the non-reducing terminus%2C although the active pockets of YesR and UGL are very similar%3B Belongs to the glycosyl hydrolase 105 family%3B KEGG: bli:BL00024 unsaturated rhamnogalacturonyl hydrolase gene gene2644 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02645 S100141_02646 S100141_02646 S100141_02646 2440306 2441271 - putative multiple-sugar transport system permease YteP Cell membrane%3B Membrane%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane. May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene2645 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02646 S100141_02647 S100141_02647 S100141_02647 2441487 2443796 + Histidine kinase Cell membrane%3B DNA-binding%3B Membrane%3B Transcription%3B Transcription regulation%3B Transmembrane%3B Transmembrane helix%3B Contains 1 HTH araC/xylS-type DNA-binding domain%3B KEGG: pod:PODO_24995 two-component system%2C sensor histidine kinase YesM gene gene2646 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02647 S100141_02648 S100141_02648 S100141_02648 2444030 2445535 - Putative ABC transporter peptide-binding protein YtcQ Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Probably part of a binding-protein-dependent transport system%3B Belongs to the bacterial solute-binding protein 1 family gene gene2647 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02648 S100141_02649 S100141_02649 S100141_02649 2445552 2446400 - putative ABC transporter permease protein YtcP Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2648 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02649 S100141_02650 S100141_02650 S100141_02650 2446571 2447335 - uncharacterized protein Belongs to the NAD(P)-dependent epimerase/dehydratase family gene gene2649 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02650 S100141_02651 S100141_02651 S100141_02651 2447353 2448240 - Putative hydrolase Hydrolase%3B Belongs to the dienelactone hydrolase family gene gene2650 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02651 S100141_02652 S100141_02652 S100141_02652 2448272 2449522 - putative amino acid permease YecA Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene2651 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02652 S100141_02653 S100141_02653 S100141_02653 2449651 2450544 + putative HTH-type transcriptional regulator YwqM Cytoplasm%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH lysR-type DNA-binding domain gene gene2652 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02653 S100141_02654 S100141_02654 S100141_02654 2450550 2450954 - Prolyl oligopeptidase KEGG: vfi:VF_A0660 prolyl oligopeptidase gene gene2653 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02654 S100141_02655 S100141_02655 larS larS 2451085 2453499 - Leucine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: dvu:DVU1196 leucyl-tRNA synthetase gene gene2654 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02655 S100141_02656 S100141_02656 S100141_02656 2453921 2454250 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2655 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02656 S100141_02657 S100141_02657 S100141_02657 2454471 2455652 - putative MFS-type transporter YttB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene2656 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02657 S100141_02658 S100141_02658 S100141_02658 2455772 2456596 - putative D-methionine-binding lipoprotein MetQ Amino-acid transport%3B Cell outer membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B This protein is a component of a D-methionine permease%2C a binding protein-dependent%2C ATP-driven transport system%3B Belongs to the NlpA lipoprotein family gene gene2657 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02658 S100141_02659 S100141_02659 S100141_02659 2456892 2457572 + putative membrane protein YttA Cell membrane%3B Coiled coil%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2658 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02659 S100141_02660 S100141_02660 S100141_02660 2457600 2458931 - ABC transporter permease YtrF Cell membrane%3B Coiled coil%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transmembrane%3B Transmembrane helix%3B Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation%3B Belongs to the ABC-4 integral membrane protein family gene gene2659 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02660 S100141_02661 S100141_02661 S100141_02661 2458921 2459619 - ABC transporter ATP-binding protein YtrE ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene2660 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02661 S100141_02662 S100141_02662 S100141_02662 2459645 2460622 - putative ABC transporter permease YtrC Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation%3B Belongs to the ABC-5 integral membrane protein family gene gene2661 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02662 S100141_02663 S100141_02663 S100141_02663 2460616 2461494 - L-arabinose transport ATP-binding protein AraG ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Repeat%3B Sugar transport%3B Transport%3B Part of the binding-protein-dependent transport system for L-arabinose. Probably responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 2 ABC transporter domains gene gene2662 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02663 S100141_02664 S100141_02664 S100141_02664 2461487 2461879 - HTH-type transcriptional repressor YtrA DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Negatively regulates ABC transporter complex ytrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation%3B Contains 1 HTH gntR-type DNA-binding domain gene gene2663 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02664 S100141_02665 S100141_02665 S100141_02665 2461922 2462050 - hypothetical protein gene gene2664 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02665 S100141_02666 S100141_02666 S100141_02666 2462176 2462448 - uncharacterized protein Coiled coil. gene gene2665 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02666 S100141_02667 S100141_02667 S100141_02667 2462601 2463569 + Putative protein YtqA 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B S-adenosyl-L-methionine%3B Belongs to the radical SAM superfamily gene gene2666 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02667 S100141_02668 S100141_02668 S100141_02668 2463566 2464150 + Putative rRNA methylase YtqB Methyltransferase%3B Transferase%3B Belongs to the methyltransferase superfamily gene gene2667 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02668 S100141_02669 S100141_02669 S100141_02669 2464331 2465581 + Proton glutamate symport protein Cell membrane%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B This carrier protein is part of the Na(+)-dependent%2C binding-protein-independent glutamate-aspartate transport system. Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family gene gene2668 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02669 S100141_02670 S100141_02670 ytpB ytpB 2465622 2466701 - Tetraprenyl-beta-curcumene synthase Lyase%3B Catalyzes the transformation of a linear C35 prenyl diphosphate chain to form tetraprenyl-beta-curcumene%3B KEGG: bsu:BSU30500 tetraprenyl-beta-curcumene synthase gene gene2669 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02670 S100141_02671 S100141_02671 pldB pldB 2466716 2467495 - Lysophospholipase Antibiotic biosynthesis%3B Hydrolase%3B Serine esterase%3B Phospholipase involved in the biosynthesis of the antibiotic bacilysocin. It probably catalyzes the hydrolysis of the 2-sn-acyl moiety of phosphatidylglycerol to produce bacilysocin (lysophosphatidylglycerol). Is also able to catalyze the hydrolysis reaction of one acyl bond in phosphatidylcholine in vitro (actual cleavage point is unknown)%2C resulting in lysophosphatidylcholine%3B Belongs to the AB hydrolase superfamily%3B KEGG: bli:BL00003 lysophospholipase gene gene2670 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02671 S100141_02672 S100141_02672 S100141_02672 2467539 2468057 + putative transferase YtoA Transferase%3B Belongs to the transferase hexapeptide repeat family gene gene2671 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02672 S100141_02673 S100141_02673 S100141_02673 2468234 2468758 + Undecaprenyl-diphosphate phosphatase KEGG: bli:BL00058 undecaprenyl-diphosphatase gene gene2672 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02673 S100141_02674 S100141_02674 S100141_02674 2468817 2469953 + GDP-mannose-dependent alpha-mannosyltransferase Glycosyltransferase%3B Lipid biosynthesis%3B Lipid metabolism%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B Catalyzes the addition of a mannose residue from GDP-D- mannose to GlcAGroAc2 to generate 1%2C2-di-O-C16/C18:1-(alpha-D- mannopyranosyl)-(1-4)-(alpha-D-glucopyranosyluronic acid)-(1-3)- glycerol(ManGlcAGroAc2)%3B Belongs to the glycosyltransferase group 1 family%3B KEGG: bcz:BCZK4513 null%3B Hexosyltransferases gene gene2673 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02674 S100141_02675 S100141_02675 S100141_02675 2469997 2471895 - Asparagine synthase (glutamine-hydrolyzing) Amino-acid biosynthesis%3B Asparagine biosynthesis%3B ATP-binding%3B Glutamine amidotransferase%3B Ligase%3B Nucleotide-binding%3B Main asparagine synthetase in vegetative cells. Belongs to the asparagine synthetase family%3B Contains 1 glutamine amidotransferase type-2 domain%3B KEGG: bsu:BSU30540 asparagine synthase (glutamine-hydrolysing) gene gene2674 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02675 S100141_02676 S100141_02676 metK metK 2472125 2473327 - Methionine adenosyltransferase ATP-binding%3B Cobalt%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B One-carbon metabolism%3B Potassium%3B Transferase%3B Catalyzes the formation of S-adenosylmethionine from methionine and ATP%3B Belongs to the AdoMet synthase family%3B KEGG: geo:Geob_1656 S-adenosylmethionine synthetase gene gene2675 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02676 S100141_02677 S100141_02677 pckA pckA 2474051 2475634 + Phosphoenolpyruvate carboxykinase (ATP) ATP-binding%3B Cytoplasm%3B Decarboxylase%3B Gluconeogenesis%3B Lyase%3B Manganese%3B Metal-binding%3B Nucleotide-binding%3B Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA%3B Belongs to the phosphoenolpyruvate carboxykinase [ATP] family%3B KEGG: bli:BL00839 phosphoenolpyruvate carboxykinase (ATP) gene gene2676 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02677 S100141_02678 S100141_02678 S100141_02678 2475884 2477068 + hypothetical protein gene gene2677 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02678 S100141_02679 S100141_02679 S100141_02679 2477109 2477351 - uncharacterized protein gene gene2678 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02679 S100141_02680 S100141_02680 dpp4 dpp4 2477376 2478176 - Dipeptidyl-peptidase IV Hydrolase%3B Protease%3B Serine protease%3B Belongs to the peptidase S9B family%3B KEGG: ehx:EMIHUDRAFT_466891 dipeptidyl-peptidase 4 gene gene2679 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02680 S100141_02681 S100141_02681 S100141_02681 2478284 2479276 + Putative binding protein YtlA Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Belongs to the bacterial solute-binding protein SsuA/TauA family gene gene2680 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02681 S100141_02682 S100141_02682 S100141_02682 2479289 2480077 + Lipoprotein-releasing system ATP-binding protein LolD ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins%2C from the inner membrane to the periplasmic chaperone%2C LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner%3B Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3. A. 1. 125) family%3B Contains 1 ABC transporter domain gene gene2681 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02682 S100141_02683 S100141_02683 S100141_02683 2480040 2480864 + putative ABC transporter permease protein YtlD Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene2682 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02683 S100141_02684 S100141_02684 S100141_02684 2480895 2481371 - 8-oxo-dGTP diphosphatase Hydrolase%3B Magnesium%3B Metal-binding%3B Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7%2C8-dihydro-8-oxoguanine%2C 8- oxo-dGTP) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A. T to G. C transversions (By similarity). Functions%2C in conjuction with MutT%2C to protect vegetatively growing cells from DNA-damaging agents such as H(2)O(2) or t-BHP (t-butylhydroperoxide). The 2 proteins do not however protect spores. According to PubMed:15576788%2C phosphohydrolase that catalyzes the hydrolysis of all common nucleoside triphosphates as well as of the mutagenic analog 8-oxo- dGTP. The high catalytic efficiency on dGTP is in contrast to results from PubMed:14761999. According to PubMed:14761999%2C catalyzes the hydrolysis of 8-oxo-dGTP with a specific activity 413 times higher than that exhibited against dGTP. Preferentially catalyzes the hydrolysis of 8-oxo-dGTP and 8-oxo-GTP. According to PubMed:15576788%2C hydrolyzes nucleoside triphosphates in a stepwise fashion through the diphosphate to the monophosphate%2C releasing two molecules of inorganic orthophosphate%3B Belongs to the Nudix hydrolase family%3B Contains 1 nudix hydrolase domain%3B KEGG: bsu:BSU30630 8-oxo-dGTP diphosphatase gene gene2683 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02684 S100141_02685 S100141_02685 S100141_02685 2481566 2481889 - hypothetical protein gene gene2684 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02685 S100141_02686 S100141_02686 S100141_02686 2481937 2482341 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the Cp-1 holin family gene gene2685 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02686 S100141_02687 S100141_02687 S100141_02687 2482494 2482931 - DNA protection during starvation protein Cytoplasm%3B Iron%3B Iron storage%3B Metal-binding%3B Oxidoreductase%3B Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions%2C which prevents hydroxyl radical production by the Fenton Fe(2+) ion (By similarity). It is capable of binding and sequestering Fe(2+) ion. Does not bind DNA%3B Belongs to the Dps family gene gene2686 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02687 S100141_02688 S100141_02688 S100141_02688 2483065 2483208 + hypothetical protein gene gene2687 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02688 S100141_02689 S100141_02689 S100141_02689 2483202 2483645 - uncharacterized protein gene gene2688 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02689 S100141_02690 S100141_02690 luxS luxS 2483777 2484250 - S-ribosylhomocysteine lyase Autoinducer synthesis%3B Iron%3B Lyase%3B Metal-binding%3B Quorum sensing%3B Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4%2C5- dihydroxy-2%2C3-pentadione (DPD)%3B Belongs to the LuxS family%3B KEGG: bsu:BSU30670 S-ribosylhomocysteine lyase gene gene2689 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02690 S100141_02691 S100141_02691 S100141_02691 2484388 2484615 + Putative membrane protein insertion efficiency factor Cell membrane%3B Membrane%3B Could be involved in insertion of integral membrane proteins into the membrane%3B Belongs to the UPF0161 family gene gene2690 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02691 S100141_02692 S100141_02692 cynT cynT 2484612 2485181 - Carbonate dehydratase Lyase%3B Metal-binding%3B Zinc%3B Reversible hydration of carbon dioxide%3B Belongs to the beta-class carbonic anhydrase family%3B KEGG: salv:SALWKB2_2139 carbonic anhydrase gene gene2691 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02692 S100141_02693 S100141_02693 S100141_02693 2485308 2486489 + COBW domain-containing protein ATP-binding%3B Coiled coil%3B Nucleotide-binding%3B Belongs to the SIMIBI class G3E GTPase family. CobW subfamily%3B Contains 1 cobW C-terminal domain gene gene2692 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02693 S100141_02694 S100141_02694 S100141_02694 2486588 2487619 + Zinc-binding protein AdcA Ion transport%3B Signal%3B Transport%3B Zinc%3B Zinc transport%3B Part of the ATP-driven transport system AdcABC for zinc. Belongs to the bacterial solute-binding protein 9 family gene gene2693 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02694 S100141_02695 S100141_02695 S100141_02695 2487705 2487950 - 50S ribosomal protein L31 type Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L31P family. Type B subfamily gene gene2694 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02695 S100141_02696 S100141_02696 cydA cydA 2488142 2489467 + Cytochrome bd ubiquinol oxidase subunit Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the cytochrome ubiquinol oxidase subunit 1 family%3B KEGG: gbm:Gbem_2016 cytochrome d ubiquinol oxidase subunit I%3B With oxygen as acceptor gene gene2695 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02696 S100141_02697 S100141_02697 cydB cydB 2489497 2490549 + Putative cytochrome bd menaquinol oxidase subunit II Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B May have a role in sporulation. Can compensate for the loss of cytochrome aa3%3B Belongs to the cytochrome ubiquinol oxidase subunit 2 family%3B KEGG: bld:BLi03216 cytochrome d ubiquinol oxidase subunit II%3B With oxygen as acceptor gene gene2696 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02697 S100141_02698 S100141_02698 S100141_02698 2490594 2490755 + uncharacterized protein gene gene2697 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02698 S100141_02699 S100141_02699 S100141_02699 2490782 2490973 + hypothetical protein gene gene2698 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02699 S100141_02700 S100141_02700 menC menC 2491132 2492241 - o-succinylbenzoate synthase Lyase%3B Magnesium%3B Menaquinone biosynthesis%3B Metal-binding%3B Converts 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)%3B Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily%3B KEGG: bli:BL02404 O-succinylbenzoate synthase gene gene2699 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02700 S100141_02701 S100141_02701 menE menE 2492254 2493690 - o-succinylbenzoate--CoA ligase ATP-binding%3B Ligase%3B Menaquinone biosynthesis%3B Nucleotide-binding%3B Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl- CoA (OSB-CoA)%3B Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily%3B KEGG: bli:BL02405 O-succinylbenzoic acid--CoA ligase gene gene2700 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02701 S100141_02702 S100141_02702 menB menB 2493768 2494586 - 1%2C4-dihydroxy-2-naphthoyl-CoA synthase Lyase%3B Menaquinone biosynthesis%3B Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1%2C4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)%3B Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily%3B KEGG: bst:GYO_3334 naphthoate synthase gene gene2701 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02702 S100141_02703 S100141_02703 S100141_02703 2494600 2495412 - 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate synthase Lyase%3B Menaquinone biosynthesis%3B Catalyzes a proton abstraction reaction that results in 2%2C5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate (SHCHC)%3B Belongs to the AB hydrolase superfamily. MenH family%3B KEGG: bsu:BSU30810 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate synthase gene gene2702 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02703 S100141_02704 S100141_02704 menD menD 2495409 2497151 - 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acidsynthase Magnesium%3B Manganese%3B Menaquinone biosynthesis%3B Metal-binding%3B Thiamine pyrophosphate%3B Transferase%3B Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)%3B Belongs to the TPP enzyme family. MenD subfamily%3B KEGG: bli:BL02408 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase gene gene2703 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02704 S100141_02705 S100141_02705 menF menF 2497148 2498572 - Isochorismate synthase Isomerase%3B Magnesium%3B Menaquinone biosynthesis%3B Metal-binding%3B Catalyzes the conversion of chorismate to isochorismate%3B Belongs to the isochorismate synthase family%3B KEGG: bsu:BSU30830 menaquinone-specific isochorismate synthase gene gene2704 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02705 S100141_02706 S100141_02706 menA menA 2498841 2499773 + 1%2C4-dihydroxy-2-naphthoate octaprenyltransferase Cell membrane%3B Membrane%3B Menaquinone biosynthesis%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Conversion of 1%2C4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK)%3B Belongs to the MenA family. Type 1 subfamily%3B KEGG: bli:BL01413 1%2C4-dihydroxy-2-naphthoate octaprenyltransferase%3B 1%2C4-dihydroxy-2-naphthoate polyprenyltransferase gene gene2705 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02706 S100141_02707 S100141_02707 S100141_02707 2499882 2500637 + uncharacterized protein Metal-binding%3B Zinc%3B Zinc-finger%3B Contains 1 dksA C4-type zinc finger gene gene2706 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02707 S100141_02708 S100141_02708 glgP glgP 2500671 2501528 - Glycogen phosphorylase Allosteric enzyme%3B Carbohydrate metabolism%3B Glycogen metabolism%3B Glycosyltransferase%3B Pyridoxal phosphate%3B Transferase%3B Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However%2C all known phosphorylases share catalytic and structural properties. Belongs to the glycogen phosphorylase family%3B KEGG: bli:BL01415 starch phosphorylase gene gene2707 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02708 S100141_02709 S100141_02709 S100141_02709 2501636 2502127 - Glycogen phosphorylase Allosteric enzyme%3B Carbohydrate metabolism%3B Chloroplast%3B Glycosyltransferase%3B Plastid%3B Pyridoxal phosphate%3B Transferase%3B Transit peptide%3B Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However%2C all known phosphorylases share catalytic and structural properties (By similarity). May be not required for the degradation of starch%2C but the phosphorolysis of starch may play an important role in water stress tolerance%3B Belongs to the glycogen phosphorylase family%3B KEGG: eco:b3417 starch phosphorylase gene gene2708 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02709 S100141_02710 S100141_02710 S100141_02710 2502180 2503064 - Glycogen phosphorylase Allosteric enzyme%3B Carbohydrate metabolism%3B Glycogen metabolism%3B Glycosyltransferase%3B Pyridoxal phosphate%3B Transferase%3B Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However%2C all known phosphorylases share catalytic and structural properties (By similarity)%3B Belongs to the glycogen phosphorylase family%3B KEGG: blh:BaLi_c33000 starch phosphorylase gene gene2709 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02710 S100141_02711 S100141_02711 glgA glgA 2503025 2504506 - Starch synthase Glycogen biosynthesis%3B Glycosyltransferase%3B Transferase%3B Synthesizes alpha-1%2C4-glucan chains using ADP-glucose%3B Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily%3B KEGG: pat:Patl_0080 starch synthase gene gene2710 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02711 S100141_02712 S100141_02712 S100141_02712 2504503 2505531 - Glucose-1-phosphate adenylyltransferase ATP-binding%3B Carbohydrate metabolism%3B Glycogen biosynthesis%3B Glycogen metabolism%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase%3B Catalyzes the synthesis of ADP-glucose%2C a sugar donor used in elongation reactions on alpha-glucans%3B Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family%3B KEGG: bli:BL01417 glucose-1-phosphate adenylyltransferase gene gene2711 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02712 S100141_02713 S100141_02713 S100141_02713 2505558 2506697 - Glucose-1-phosphate adenylyltransferase ATP-binding%3B Carbohydrate metabolism%3B Glycogen biosynthesis%3B Glycogen metabolism%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase%3B Catalyzes the synthesis of ADP-glucose%2C a sugar donor used in elongation reactions on alpha-glucans%3B Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family%3B KEGG: bli:BL01418 glucose-1-phosphate adenylyltransferase gene gene2712 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02713 S100141_02714 S100141_02714 glgB glgB 2506694 2508577 - 1%2C4-alpha-glucan branching enzyme Carbohydrate metabolism%3B Glycogen biosynthesis%3B Glycogen metabolism%3B Glycosyltransferase%3B Transferase%3B Catalyzes the formation of the alpha-1%2C6-glucosidic linkages in glycogen by scission of a 1%2C4-alpha-linked oligosaccharide from growing alpha-1%2C4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1%2C6 position%3B Belongs to the glycosyl hydrolase 13 family. GlgB subfamily%3B KEGG: bli:BL01419 1%2C4-alpha-glucan branching enzyme gene gene2713 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02714 S100141_02715 S100141_02715 S100141_02715 2508761 2508835 - tRNA-Glu tRNA gene2714 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02715 S100141_02716 S100141_02716 S100141_02716 2508848 2508938 - tRNA-Ser tRNA gene2715 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02716 S100141_02717 S100141_02717 S100141_02717 2508940 2509014 - tRNA-Asn tRNA gene2716 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02717 S100141_02718 S100141_02718 S100141_02718 2509021 2509097 - tRNA-Ile tRNA gene2717 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02718 S100141_02719 S100141_02719 S100141_02719 2509110 2509183 - tRNA-Gly tRNA gene2718 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02719 S100141_02720 S100141_02720 S100141_02720 2509192 2509267 - tRNA-His tRNA gene2719 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02720 S100141_02721 S100141_02721 S100141_02721 2509290 2509365 - tRNA-Phe tRNA gene2720 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02721 S100141_02722 S100141_02722 S100141_02722 2509376 2509452 - tRNA-Asp tRNA gene2721 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02722 S100141_02723 S100141_02723 S100141_02723 2509498 2509574 - tRNA-Met tRNA gene2722 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02723 S100141_02724 S100141_02724 S100141_02724 2509599 2509691 - tRNA-Ser tRNA gene2723 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02724 S100141_02725 S100141_02725 S100141_02725 2509699 2509775 - tRNA-Met tRNA gene2724 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02725 S100141_02726 S100141_02726 S100141_02726 2509781 2509854 - tRNA-Met tRNA gene2725 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02726 S100141_02727 S100141_02727 S100141_02727 2509880 2509952 - tRNA-Ala tRNA gene2726 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02727 S100141_02728 S100141_02728 S100141_02728 2509959 2510035 - tRNA-Pro tRNA gene2727 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02728 S100141_02729 S100141_02729 S100141_02729 2510044 2510120 - tRNA-Arg tRNA gene2728 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02729 S100141_02730 S100141_02730 S100141_02730 2510131 2510202 - tRNA-Gly tRNA gene2729 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02730 S100141_02731 S100141_02731 S100141_02731 2510218 2510302 - tRNA-Leu tRNA gene2730 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02731 S100141_02732 S100141_02732 S100141_02732 2510309 2510384 - tRNA-Lys tRNA gene2731 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02732 S100141_02733 S100141_02733 S100141_02733 2510466 2510541 - tRNA-Thr tRNA gene2732 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02733 S100141_02734 S100141_02734 S100141_02734 2510557 2510632 - tRNA-Val tRNA gene2733 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02734 S100141_02735 S100141_02735 S100141_02735 2510828 2511034 - hypothetical protein gene gene2734 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02735 S100141_02736 S100141_02736 S100141_02736 2511359 2511474 - 5S ribosomal RNA rRNA gene2735 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02736 S100141_02737 S100141_02737 S100141_02737 2511606 2514536 - 23S ribosomal RNA rRNA gene2736 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02737 S100141_02738 S100141_02738 S100141_02738 2514708 2516258 - 16S ribosomal RNA rRNA gene2737 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02738 S100141_02739 S100141_02739 S100141_02739 2516885 2517733 - Arabinose metabolism transcriptional repressor Cytoplasm%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcriptional repressor of the arabinose utilization genes%3B Contains 1 HTH gntR-type DNA-binding domain%3B overlaps another CDS with the same product name gene gene2738 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02739 S100141_02740 S100141_02740 S100141_02740 2517730 2517984 - Arabinose metabolism transcriptional repressor Cytoplasm%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcriptional repressor of the arabinose utilization genes. Also regulates its own expression. Binds to two sequences within the promoters of the araABDLMNPQ-abfA operon and the araE gene%2C and to one sequence in the araR promoter. Contains 1 HTH gntR-type DNA-binding domain%3B overlaps another CDS with the same product name gene gene2739 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02740 S100141_02741 S100141_02741 S100141_02741 2518358 2518942 + Thiamine transporter ThiT Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably a thiamine-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane%2C not extracytoplasmic soluble proteins (By similarity)%3B Belongs to the ECF family. Thiamine transporter (TC 2. A. 88) subfamily gene gene2740 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02741 S100141_02742 S100141_02742 S100141_02742 2518983 2519540 - Sortase A Membrane%3B Transmembrane%3B Transmembrane helix%3B KEGG: blh:BaLi_c33300 sortase A gene gene2741 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02742 S100141_02743 S100141_02743 S100141_02743 2519647 2520642 - hypothetical protein gene gene2742 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02743 S100141_02744 S100141_02744 S100141_02744 2520823 2521011 + hypothetical protein gene gene2743 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02744 S100141_02745 S100141_02745 S100141_02745 2521137 2522249 + Response regulator aspartate phosphatase Hydrolase%3B Protein phosphatase%3B Repeat%3B TPR repeat%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bli:BL02513 response regulator aspartate phosphatase D%3B Acting on ester bonds gene gene2744 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02745 S100141_02746 S100141_02746 S100141_02746 2522251 2522379 + hypothetical protein gene gene2745 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02746 S100141_02747 S100141_02747 S100141_02747 2522459 2523106 + Pyroglutamyl-peptidase I Cytoplasm%3B Hydrolase%3B Protease%3B Thiol protease%3B Removes 5-oxoproline from various penultimate amino acid residues except L-proline. Belongs to the peptidase C15 family%3B KEGG: bsu:BSU02650 pyroglutamyl-peptidase gene gene2746 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02747 S100141_02748 S100141_02748 S100141_02748 2523225 2523881 + Ktr system potassium uptake protein Cell membrane%3B Ion transport%3B Membrane%3B NAD%3B Potassium%3B Potassium transport%3B Transport%3B Catalytic subunit of the KtrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress%3B Belongs to the KtrA potassium transport family%3B Contains 1 RCK C-terminal domain%3B Contains 1 RCK N-terminal domain gene gene2747 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02748 S100141_02749 S100141_02749 S100141_02749 2523884 2525203 + Ktr system potassium uptake protein Cell membrane%3B Ion transport%3B Membrane%3B Potassium%3B Potassium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Integral membrane subunit of the KtrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress%3B Belongs to the TrkH potassium transport family. Ktr (TC 2. A. 38. 4) subfamily gene gene2748 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02749 S100141_02750 S100141_02750 S100141_02750 2525214 2526128 - putative transporter Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene2749 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02750 S100141_02751 S100141_02751 S100141_02751 2526252 2526734 + uncharacterized protein gene gene2750 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02751 S100141_02752 S100141_02752 S100141_02752 2526781 2527362 - Putative metal-sulfur cluster biosynthesis protein YuaD Contains 1 MOSC domain gene gene2751 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02752 S100141_02753 S100141_02753 S100141_02753 2527474 2528682 - Alcohol dehydrogenase Alternative initiation%3B NAD%3B Oxidoreductase%3B Essential for the utilization of choline as a precursor%3B Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: bsu:BSU31050 choline dehydrogenase gene gene2752 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02753 S100141_02754 S100141_02754 S100141_02754 2528700 2530172 - Betaine-aldehyde dehydrogenase NAD%3B Oxidoreductase%3B This is a soluble NAD-dependent betaine aldehyde- specific dehydrogenase. Essential for the utilization of choline as a precursor%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: bsu:BSU31060 betaine-aldehyde dehydrogenase gene gene2753 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02754 S100141_02755 S100141_02755 S100141_02755 2530496 2531050 + HTH-type transcriptional repressor GbsR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Negatively regulates the expression of the gbsAB and opuB operons. Required to control expression of these genes in response to choline availability. Also required to downregulate glycine betaine production once cellular adjustment to high osmolarity has been achieved%3B Belongs to the GbsR family gene gene2754 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02755 S100141_02756 S100141_02756 S100141_02756 2531170 2532798 + High-affinity choline transporter Glycoprotein%3B Ion transport%3B Membrane%3B Neurotransmitter biosynthesis%3B Sodium%3B Sodium transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Imports choline from the extracellular space to the neuron with high affinity. Rate-limiting step in acetylcholine synthesis. Sodium ion and chloride ion dependent (By similarity)%3B Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene2755 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02756 S100141_02757 S100141_02757 S100141_02757 2532842 2533759 - Putative S-adenosyl-L-methionine-dependent methyltransferase YktD Methyltransferase%3B Transferase%3B May be involved in polyketide synthesis. Belongs to the UPF0677 family gene gene2756 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02757 S100141_02758 S100141_02758 S100141_02758 2533934 2535115 - Alanine racemase Isomerase%3B Pyridoxal phosphate%3B Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids%3B Belongs to the alanine racemase family%3B KEGG: bsu:BSU17640 alanine racemase gene gene2757 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02758 S100141_02759 S100141_02759 oxdD oxdD 2535430 2536611 + Oxalate decarboxylase Cytoplasm%3B Decarboxylase%3B Lyase%3B Manganese%3B Metal-binding%3B Converts oxalate to formate and CO(2). To B. subtilis OxdC%3B KEGG: bsm:BSM4216_3794 oxalate decarboxylase gene gene2758 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02759 S100141_02760 S100141_02760 S100141_02760 2537150 2537671 + hypothetical protein gene gene2759 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02760 S100141_02761 S100141_02761 S100141_02761 2537679 2538638 + hypothetical protein gene gene2760 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02761 S100141_02762 S100141_02762 S100141_02762 2539059 2539733 - N-acetylmuramoyl-L-alanine amidase Cell wall biogenesis/degradation%3B Hydrolase%3B Repeat%3B Secreted%3B Signal%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B KEGG: bli:BL01582 N-acetylmuramoyl-L-alanine amidase gene gene2761 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02762 S100141_02763 S100141_02763 S100141_02763 2539860 2540042 + hypothetical protein gene gene2762 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02763 S100141_02764 S100141_02764 S100141_02764 2540102 2540174 - tRNA-Ala tRNA gene2763 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02764 S100141_02765 S100141_02765 S100141_02765 2540412 2540810 - hypothetical protein gene gene2764 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02765 S100141_02766 S100141_02766 S100141_02766 2540825 2542747 - hypothetical protein gene gene2765 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02766 S100141_02767 S100141_02767 S100141_02767 2542767 2543090 - hypothetical protein gene gene2766 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02767 S100141_02768 S100141_02768 S100141_02768 2543087 2543794 - hypothetical protein gene gene2767 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02768 S100141_02769 S100141_02769 S100141_02769 2543812 2544162 - hypothetical protein gene gene2768 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02769 S100141_02770 S100141_02770 S100141_02770 2544181 2544540 - hypothetical protein gene gene2769 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02770 S100141_02771 S100141_02771 S100141_02771 2544834 2545043 + uncharacterized protein gene gene2770 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02771 S100141_02772 S100141_02772 S100141_02772 2545066 2545239 + hypothetical protein gene gene2771 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02772 S100141_02773 S100141_02773 S100141_02773 2545260 2546741 - hypothetical protein gene gene2772 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02773 S100141_02774 S100141_02774 S100141_02774 2546758 2547891 - 1%2C2-diacylglycerol 3-glucosyltransferase Glycosyltransferase%3B Transferase%3B Belongs to the glycosyltransferase 28 family%3B KEGG: pjd:Pjdr2_5001 processive 1%2C2-diacylglycerol beta-glucosyltransferase gene gene2773 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02774 S100141_02775 S100141_02775 S100141_02775 2547991 2548539 + uncharacterized protein gene gene2774 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02775 S100141_02776 S100141_02776 S100141_02776 2548584 2549399 - putative metallophosphoesterase YkoQ Hydrolase%3B Metal-binding%3B Belongs to the metallophosphoesterase superfamily gene gene2775 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02776 S100141_02777 S100141_02777 S100141_02777 2549531 2550361 - Undecaprenyl-diphosphate phosphatase Antibiotic resistance%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Membrane%3B Peptidoglycan synthesis%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin%3B Belongs to the UppP family%3B KEGG: bli:BL02576 undecaprenyl-diphosphatase gene gene2776 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02777 S100141_02778 S100141_02778 S100141_02778 2550439 2551584 - UPF0118 membrane protein YubA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0118 (PerM) family gene gene2777 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02778 S100141_02779 S100141_02779 S100141_02779 2551799 2552782 + D-xylose 1-dehydrogenase (NADP(+)) NADP%3B Oxidoreductase%3B Plasmid%3B Secreted%3B Signal%3B NADP-dependent D-xylose dehydrogenase involved in the degradation of D-xylose%2C a major component of hemicelluloses such as xylan. Even if it shows D-xylose dehydrogenase activity%2C it is not essential for D-xylose degradation%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: lsa:LSA1535 null%3B Oxidoreductases gene gene2778 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02779 S100141_02780 S100141_02780 S100141_02780 2552827 2553351 - uncharacterized protein Belongs to the peptidase C56 family%3B Contains 1 PfpI endopeptidase domain%3B KEGG: dsa:Desal_2750 protease I%3B Glycosylases gene gene2779 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02780 S100141_02781 S100141_02781 S100141_02781 2553484 2555466 - Methyl-accepting chemotaxis protein McpB Cell membrane%3B Chemotaxis%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpB is required for taxis towards asparagine%2C aspartate%2C glutamine%2C and histidine%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene2780 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02781 S100141_02782 S100141_02782 S100141_02782 2555600 2557585 - Methyl-accepting chemotaxis protein McpA Cell membrane%3B Chemotaxis%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpA is required for taxis towards glucose and alpha-methylglucoside%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene2781 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02782 S100141_02783 S100141_02783 S100141_02783 2557731 2558915 - Methyl-accepting chemotaxis protein McpA Cell membrane%3B Chemotaxis%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpA is required for taxis towards glucose and alpha-methylglucoside%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene2782 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02783 S100141_02784 S100141_02784 S100141_02784 2558896 2559708 - Methyl-accepting chemotaxis protein McpB Cell membrane%3B Chemotaxis%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpB is required for taxis towards asparagine%2C aspartate%2C glutamine%2C and histidine%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene2783 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02784 S100141_02785 S100141_02785 S100141_02785 2559830 2560576 + Protein-glutamine gamma-glutamyltransferase Acyltransferase%3B Sporulation%3B Transferase%3B Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links%3B Belongs to the bacillus TGase family%3B KEGG: blh:BaLi_c33790 protein-glutamine gamma-glutamyltransferase gene gene2784 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02785 S100141_02786 S100141_02786 S100141_02786 2560556 2561611 - Nitronate monooxygenase Flavoprotein%3B FMN%3B Monooxygenase%3B Oxidoreductase%3B Catalyzes the oxidation of alkyl nitronates to produce the corresponding carbonyl compounds and nitrites%3B Belongs to the nitronate monooxygenase family%3B KEGG: bli:BL02583 nitronate monooxygenase gene gene2785 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02786 S100141_02787 S100141_02787 S100141_02787 2561627 2562028 - Nitronate monooxygenase Belongs to the UPF0047 family%3B KEGG: bao:BAMF_2926 nitronate monooxygenase gene gene2786 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02787 S100141_02788 S100141_02788 S100141_02788 2562067 2563749 - Alpha-glucosidase Cytoplasm%3B Glycosidase%3B Hydrolase%3B Belongs to the glycosyl hydrolase 13 family%3B KEGG: aza:AZKH_2678 alpha-glucosidase gene gene2787 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02788 S100141_02789 S100141_02789 S100141_02789 2564052 2564642 + hypothetical protein gene gene2788 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02789 S100141_02790 S100141_02790 S100141_02790 2564639 2565313 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2789 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02790 S100141_02791 S100141_02791 S100141_02791 2565396 2566181 - Xyloglucan-specific endo-beta-1%2C4-glucanase Carbohydrate metabolism%3B Cellulose degradation%3B Glycosidase%3B Hydrolase%3B Polysaccharide degradation%3B Signal%3B Belongs to the glycosyl hydrolase 12 (cellulase H) family%3B KEGG: tre:TRIREDRAFT_123232 xyloglucan-specific endo-beta-1%2C4-glucanase gene gene2790 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02791 S100141_02792 S100141_02792 S100141_02792 2566362 2567651 - UPF0053 protein YhdP CBS domain%3B Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0053 family%3B Contains 2 CBS domains%3B Contains 1 DUF21 domain gene gene2791 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02792 S100141_02793 S100141_02793 S100141_02793 2567702 2568382 - Putative membrane protease YugP Cell membrane%3B Hydrolase%3B Membrane%3B Metal-binding%3B Metalloprotease%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Zinc. gene gene2792 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02793 S100141_02794 S100141_02794 S100141_02794 2568476 2568652 - hypothetical protein gene gene2793 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02794 S100141_02795 S100141_02795 S100141_02795 2568850 2569137 + Protein mistic Cell membrane%3B Chaperone%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Chaperone that facilitates the production and integration of integral membrane proteins into the bacterial lipid bilayer gene gene2794 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02795 S100141_02796 S100141_02796 S100141_02796 2569134 2570117 + Putative potassium channel protein YugO Cell membrane%3B Ion channel%3B Ion transport%3B Membrane%3B Potassium%3B Potassium channel%3B Potassium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Contains 1 RCK N-terminal domain gene gene2795 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02796 S100141_02797 S100141_02797 S100141_02797 2570114 2570518 - uncharacterized protein gene gene2796 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02797 S100141_02798 S100141_02798 S100141_02798 2570660 2571121 - UPF0702 transmembrane protein YdfR Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0702 family gene gene2797 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02798 S100141_02799 S100141_02799 S100141_02799 2571239 2571715 + putative membrane protein YtaB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the TspO/BZRP family gene gene2798 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02799 S100141_02800 S100141_02800 S100141_02800 2571784 2572308 + Ribosomal-protein-alanine N-acetyltransferase Acyltransferase%3B Transferase%3B Contains 1 N-acetyltransferase domain%3B KEGG: bha:BH0837 ribosomal-protein-alanine N-acetyltransferase gene gene2799 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02800 S100141_02801 S100141_02801 S100141_02801 2572641 2573324 + hypothetical protein gene gene2800 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02801 S100141_02802 S100141_02802 S100141_02802 2573426 2573794 + SPBc2 prophage-derived uncharacterized protein YolD gene gene2801 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02802 S100141_02803 S100141_02803 S100141_02803 2573819 2574049 - hypothetical protein gene gene2802 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02803 S100141_02804 S100141_02804 S100141_02804 2574304 2574447 - hypothetical protein gene gene2803 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02804 S100141_02805 S100141_02805 S100141_02805 2574623 2575075 + hypothetical protein gene gene2804 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02805 S100141_02806 S100141_02806 S100141_02806 2575072 2575476 + hypothetical protein gene gene2805 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02806 S100141_02807 S100141_02807 S100141_02807 2575478 2575675 - putative 10.3 kDa protein in GP2-GP6 intergenic region gene gene2806 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02807 S100141_02808 S100141_02808 S100141_02808 2575972 2577471 + Ribonuclease YxiD Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene2807 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02808 S100141_02809 S100141_02809 S100141_02809 2577486 2577884 + hypothetical protein gene gene2808 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02809 S100141_02810 S100141_02810 S100141_02810 2577930 2579009 - N-acetylmuramoyl-L-alanine amidase Cell wall biogenesis/degradation%3B Hydrolase%3B Repeat%3B Secreted%3B Signal%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B KEGG: bli:BL01582 N-acetylmuramoyl-L-alanine amidase gene gene2809 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02810 S100141_02811 S100141_02811 S100141_02811 2579061 2579324 - SPBc2 prophage-derived protein BhlB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B May be involved in the secretion of the autolysin BlyA. Belongs to the SPP1 holin family gene gene2810 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02811 S100141_02812 S100141_02812 S100141_02812 2579340 2579609 - putative 11.0 kDa protein in cwlL 5'region To B. licheniformis xpaL1 and to B. subtilis XhlA gene gene2811 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02812 S100141_02813 S100141_02813 S100141_02813 2579672 2579854 - hypothetical protein gene gene2812 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02813 S100141_02814 S100141_02814 S100141_02814 2579851 2580174 - SPBc2 prophage-derived uncharacterized protein YomQ gene gene2813 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02814 S100141_02815 S100141_02815 S100141_02815 2580187 2581536 - uncharacterized protein To B. subtilis XkdV gene gene2814 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02815 S100141_02816 S100141_02816 S100141_02816 2581550 2584195 - Putative phage-related protein YobO Repeat%3B Contains 6 PbH1 repeats gene gene2815 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02816 S100141_02817 S100141_02817 S100141_02817 2584232 2585944 - N-acetylmuramoyl-L-alanine amidase Cell wall%3B Cell wall biogenesis/degradation%3B Glycosidase%3B Hydrolase%3B Magnesium%3B Secreted%3B Signal%3B Is the major glucosaminidase responsible for peptidoglycan structural determination during vegetative growth. Acts processively from the ends of the glycan strands. Also plays a role in motility%2C chemotaxis and cell division%3B Belongs to the glycosyl hydrolase 73 family%3B KEGG: smu:SMU_76 N-acetylmuramoyl-L-alanine amidase gene gene2816 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02817 S100141_02818 S100141_02818 S100141_02818 2585957 2586793 - hypothetical protein gene gene2817 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02818 S100141_02819 S100141_02819 S100141_02819 2586793 2591262 - Tape measure protein Host membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Viral tail assembly%3B Virus exit from host cell%3B Plays a role in virion tail formation. The length of the tape measure protein is proportional to the length of the phage's tail gene gene2818 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02819 S100141_02820 S100141_02820 S100141_02820 2591325 2591423 - hypothetical protein gene gene2819 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02820 S100141_02821 S100141_02821 S100141_02821 2591471 2591836 - hypothetical protein gene gene2820 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02821 S100141_02822 S100141_02822 S100141_02822 2591890 2592507 - hypothetical protein gene gene2821 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02822 S100141_02823 S100141_02823 S100141_02823 2592522 2592905 - hypothetical protein gene gene2822 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02823 S100141_02824 S100141_02824 S100141_02824 2592902 2593300 - hypothetical protein gene gene2823 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02824 S100141_02825 S100141_02825 S100141_02825 2593300 2593608 - hypothetical protein gene gene2824 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02825 S100141_02826 S100141_02826 S100141_02826 2593598 2593900 - hypothetical protein gene gene2825 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02826 S100141_02827 S100141_02827 S100141_02827 2593921 2594346 - Collagen alpha chain Alternative splicing%3B Cell membrane%3B Coiled coil%3B Collagen%3B Membrane%3B Repeat%3B Signal-anchor%3B Transmembrane%3B Transmembrane helix%3B Contains 7 collagen-like domains gene gene2826 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02827 S100141_02828 S100141_02828 S100141_02828 2594369 2595679 - hypothetical protein gene gene2827 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02828 S100141_02829 S100141_02829 S100141_02829 2595719 2596450 - Endopeptidase Clp Cytoplasm%3B Hydrolase%3B Protease%3B Serine protease%3B Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins%3B Belongs to the peptidase S14 family%3B KEGG: cba:CLB_2447 ATP-dependent Clp protease%2C protease subunit gene gene2828 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02829 S100141_02830 S100141_02830 S100141_02830 2596395 2597705 - hypothetical protein gene gene2829 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02830 S100141_02831 S100141_02831 S100141_02831 2597706 2597900 - hypothetical protein gene gene2830 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02831 S100141_02832 S100141_02832 S100141_02832 2597910 2599619 - Putative terminase large subunit Viral genome packaging%3B Virus exit from host cell%3B Belongs to the phage terminase family gene gene2831 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02832 S100141_02833 S100141_02833 S100141_02833 2599616 2600131 - hypothetical protein gene gene2832 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02833 S100141_02834 S100141_02834 S100141_02834 2600362 2600736 - hypothetical protein gene gene2833 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02834 S100141_02835 S100141_02835 S100141_02835 2600763 2601071 - hypothetical protein gene gene2834 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02835 S100141_02836 S100141_02836 S100141_02836 2601286 2601510 - Spore coat protein Sporulation. gene gene2835 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02836 S100141_02837 S100141_02837 S100141_02837 2602249 2602629 - hypothetical protein gene gene2836 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02837 S100141_02838 S100141_02838 S100141_02838 2603004 2603828 + hypothetical protein gene gene2837 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02838 S100141_02839 S100141_02839 S100141_02839 2603912 2604106 - hypothetical protein gene gene2838 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02839 S100141_02840 S100141_02840 S100141_02840 2604230 2604571 - hypothetical protein gene gene2839 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02840 S100141_02841 S100141_02841 S100141_02841 2604621 2604734 - hypothetical protein gene gene2840 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02841 S100141_02842 S100141_02842 S100141_02842 2604731 2604901 - hypothetical protein gene gene2841 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02842 S100141_02843 S100141_02843 S100141_02843 2604898 2605437 - hypothetical protein gene gene2842 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02843 S100141_02844 S100141_02844 S100141_02844 2605434 2605871 - hypothetical protein gene gene2843 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02844 S100141_02845 S100141_02845 S100141_02845 2606140 2608578 - Putative helicase L207/L206 ATP-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Contains 1 SF3 helicase domain gene gene2844 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02845 S100141_02846 S100141_02846 S100141_02846 2608639 2609079 - hypothetical protein gene gene2845 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02846 S100141_02847 S100141_02847 S100141_02847 2609079 2610011 - hypothetical protein gene gene2846 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02847 S100141_02848 S100141_02848 S100141_02848 2610015 2610572 - hypothetical protein gene gene2847 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02848 S100141_02849 S100141_02849 S100141_02849 2610665 2610931 - hypothetical protein gene gene2848 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02849 S100141_02850 S100141_02850 S100141_02850 2610888 2611004 - hypothetical protein gene gene2849 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02850 S100141_02851 S100141_02851 S100141_02851 2611001 2611267 - hypothetical protein gene gene2850 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02851 S100141_02852 S100141_02852 S100141_02852 2611391 2611660 - hypothetical protein gene gene2851 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02852 S100141_02853 S100141_02853 S100141_02853 2611666 2611851 - hypothetical protein gene gene2852 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02853 S100141_02854 S100141_02854 S100141_02854 2612120 2612548 + hypothetical protein gene gene2853 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02854 S100141_02855 S100141_02855 S100141_02855 2612557 2612979 + putative immunity region protein gene gene2854 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02855 S100141_02856 S100141_02856 S100141_02856 2613024 2614172 + ICEBs1 integrase DNA integration%3B DNA recombination%3B DNA-binding%3B Viral genome integration%3B Virus entry into host cell%3B Putative integrase that is involved in the insertion of the integrative and conjugative element ICEBs1. Required for the excision of ICEBs1 from the donor cell genome and subsequent integration in the recipient cell genome. Appears not to be transferred through the mating pore. Integration of ICEBs1 involves an attachment site in the chromosome%2C attB%2C and a site in the circular form of ICEBs1%2C attICEBs1%3B Belongs to the 'phage' integrase family gene gene2855 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02856 S100141_02857 S100141_02857 S100141_02857 2614256 2615608 - Glucose-6-phosphate isomerase Cytoplasm%3B Gluconeogenesis%3B Glycolysis%3B Isomerase%3B Phosphoprotein%3B Belongs to the GPI family%3B KEGG: bsu:BSU31350 glucose-6-phosphate isomerase gene gene2856 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02857 S100141_02858 S100141_02858 S100141_02858 2615898 2617061 - putative NADH-dependent butanol dehydrogenase NAD%3B Oxidoreductase%3B Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: bsu:BSU31370 null%3B With NAD(+) or NADP(+) as acceptor gene gene2857 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02858 S100141_02859 S100141_02859 S100141_02859 2617204 2617440 + putative membrane protein YuzA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2858 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02859 S100141_02860 S100141_02860 S100141_02860 2617673 2618062 - General stress protein Cytoplasm%3B Stress response%3B Contains 1 S1 motif domain gene gene2859 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02860 S100141_02861 S100141_02861 S100141_02861 2618266 2619438 - Putative aminotransferase YugH Amino-acid biosynthesis%3B Aminotransferase%3B Cytoplasm%3B Pyridoxal phosphate%3B Transferase%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bli:BL02594 aminotransferase%3B Transaminases gene gene2860 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02861 S100141_02862 S100141_02862 S100141_02862 2619439 2619939 - putative HTH-type transcriptional regulator YugG DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH asnC-type DNA-binding domain gene gene2861 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02862 S100141_02863 S100141_02863 dhaA dhaA 2620144 2620965 + Haloalkane dehalogenase Hydrolase%3B Serine esterase%3B Belongs to the DmpD/TodF/XylF esterase family%3B KEGG: hme:HFX_2390 haloalkane dehalogenase gene gene2862 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02863 S100141_02864 S100141_02864 S100141_02864 2621005 2621262 - uncharacterized protein gene gene2863 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02864 S100141_02865 S100141_02865 S100141_02865 2621339 2621836 - hypothetical protein gene gene2864 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02865 S100141_02866 S100141_02866 S100141_02866 2621943 2623106 + Cystathionine beta-lyase Amino-acid biosynthesis%3B Lyase%3B Methionine biosynthesis%3B Pyridoxal phosphate%3B Catalyzes the transformation of cystathionine to homocysteine. Also exhibits cysteine desulfhydrase activity in vitro%2C producing sulfide from cysteine. Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. MalY/PatB cystathionine beta-lyase subfamily%3B KEGG: bli:BL02532 cystathione beta-lyase gene gene2865 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02866 S100141_02867 S100141_02867 S100141_02867 2623133 2623333 - hypothetical protein gene gene2866 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02867 S100141_02868 S100141_02868 S100141_02868 2623401 2623790 + Kinase-associated lipoprotein Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal. gene gene2867 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02868 S100141_02869 S100141_02869 S100141_02869 2623818 2624435 - putative 3'-5' exonuclease KapD Exonuclease%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nuclease%3B Sporulation%3B Specifically inhibits the KinA pathway to sporulation%3B Contains 1 exonuclease domain gene gene2868 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02869 S100141_02870 S100141_02870 S100141_02870 2624654 2625922 + Multi-drug resistance efflux pump PmrA like protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Efflux pump for various substrates%3B Belongs to the major facilitator superfamily. TCR/Tet family gene gene2869 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02870 S100141_02871 S100141_02871 S100141_02871 2626056 2627891 + Penicillin-binding protein Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Peptidoglycan synthesis%3B Signal%3B In the N-terminal sectio%3B belongs to the glycosyltransferase 51 family%3B In the C-terminal sectio%3B belongs to the transpeptidase family gene gene2870 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02871 S100141_02872 S100141_02872 S100141_02872 2627915 2628322 + Alpha-N-acetylgalactosaminidase Belongs to the DCC thiol-disulfide oxidoreductase family%3B KEGG: dfa:DFA_08734 alpha-N-acetylgalactosaminidase gene gene2871 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02872 S100141_02873 S100141_02873 S100141_02873 2628373 2628930 - putative membrane protein YufK Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2872 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02873 S100141_02874 S100141_02874 S100141_02874 2629117 2629572 + Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of a two-component regulatory system MalK/MalR. Involved in the activation of maeA%2C maeN and yflS in presence of malate. Probably activates MalR by phosphorylation%3B Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bsu:BSU31520 two-component system%2C CitB family%2C sensor histidine kinase MalK gene gene2873 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02874 S100141_02875 S100141_02875 S100141_02875 2629683 2630717 + Histidine kinase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system DcuR/DcuS. Involved in the C4-dicarboxylate-stimulated regulation of the genes encoding the anaerobic fumarate respiratory system (frdABC%3B nuoA%3B dcu%3B dcu%3B sdhCDA%3B etc.). Weakly regulates the aerobic C4-dicarboxylate transporter dctA. Activates DcuR by phosphorylation (By similarity)%3B Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bli:BL02538 two-component system%2C CitB family%2C sensor histidine kinase MalK gene gene2874 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02875 S100141_02876 S100141_02876 S100141_02876 2630710 2631417 + Chemotaxis response regulator protein-glutamate methylesterase Chemotaxis%3B Cytoplasm%3B Hydrolase%3B Phosphoprotein%3B Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene2875 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02876 S100141_02877 S100141_02877 cho1 cho1 2631972 2632508 + CDP-diacylglycerol--serine O-phosphatidyltransferase Cell membrane%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Belongs to the CDP-alcohol phosphatidyltransferase class-I family%3B KEGG: bli:BL02540 CDP-diacylglycerol---serine O-phosphatidyltransferase gene gene2876 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02877 S100141_02878 S100141_02878 S100141_02878 2632515 2632997 + putative membrane protein YbfM Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the DedA family gene gene2877 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02878 S100141_02879 S100141_02879 pisD pisD 2633040 2633654 + Phosphatidylserine decarboxylase Decarboxylase%3B Lipid biosynthesis%3B Lipid metabolism%3B Lyase%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Pyruvate%3B Zymogen%3B Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily%3B KEGG: bli:BL02542 phosphatidylserine decarboxylase%3B overlaps another CDS with the same product name gene gene2878 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02879 S100141_02880 S100141_02880 S100141_02880 2633654 2633830 + Phosphatidylserine decarboxylase Decarboxylase%3B Lipid biosynthesis%3B Lipid metabolism%3B Lyase%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Pyruvate%3B Zymogen%3B Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily%3B KEGG: bli:BL02542 phosphatidylserine decarboxylase%3B overlaps another CDS with the same product name gene gene2879 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02880 S100141_02881 S100141_02881 S100141_02881 2634102 2635445 + Na(+)-malate symporter Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Acts as a Na(+)-malate symporter%2C as it catalyzes malate-dependent uptake of Na(+) and Na(+)-dependent uptake of malate%3B Belongs to the sodium:citrate (SCF) symporter family gene gene2880 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02881 S100141_02882 S100141_02882 S100141_02882 2635505 2635738 - hypothetical protein gene gene2881 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02882 S100141_02883 S100141_02883 S100141_02883 2635984 2638386 + Na(+)/H(+) antiporter subunit A1 Antiport%3B Cell membrane%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion%3B Belongs to the CPA3 antiporters (TC 2. A. 63) subunit A family gene gene2882 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02883 S100141_02884 S100141_02884 S100141_02884 2638383 2638814 + Na(+)/H(+) antiporter subunit Antiport%3B Cell membrane%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mnh complex is a Na(+)Li(+)/H(+) antiporter involved in Na(+) and/or Li(+) excretion and Na(+) resistance. Na(+)/H(+) antiport consumes a transmembrane electrical potential%2C and is thus inferred to be electrogenic. Does not transport K(+)%2C Ca(2+) or Mg(2+). Belongs to the CPA3 antiporters (TC 2. A. 63) subunit B family gene gene2883 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02884 S100141_02885 S100141_02885 S100141_02885 2638814 2639155 + Na(+)/H(+) antiporter subunit C1 Antiport%3B Cell membrane%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion%3B Belongs to the CPA3 antiporters (TC 2. A. 63) subunit C family gene gene2884 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02885 S100141_02886 S100141_02886 S100141_02886 2639139 2640626 + Putative antiporter subunit mnhD2 Antiport%3B Cell membrane%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the CPA3 antiporters (TC 2. A. 63) subunit D family gene gene2885 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02886 S100141_02887 S100141_02887 S100141_02887 2640632 2641108 + Na(+)/H(+) antiporter subunit E1 Antiport%3B Cell membrane%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion%3B Belongs to the CPA3 antiporters (TC 2. A. 63) subunit E family gene gene2886 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02887 S100141_02888 S100141_02888 S100141_02888 2641108 2641392 + Na(+)/H(+) antiporter subunit Antiport%3B Cell membrane%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B. subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter%2C although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+)%2C Ca(2+) or Mg(2+). Involved in cholate and Na(+) efflux activities%2C which may be mechanistically coupled. Does not require other Mrp proteins for its own function. Belongs to the CPA3 antiporters (TC 2. A. 63) subunit F family%3B overlaps another CDS with the same product name gene gene2887 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02888 S100141_02889 S100141_02889 S100141_02889 2641376 2641750 + Na(+)/H(+) antiporter subunit Antiport%3B Cell membrane%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B May enhance MrpA stability%2C assembly%2C or function. May play chaperone or assembly roles for MrpA and perhaps for other mrp proteins. Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B. subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter%2C although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+)%2C Ca(2+) or Mg(2+). Belongs to the CPA3 antiporters (TC 2. A. 63) subunit G family%3B overlaps another CDS with the same product name gene gene2888 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02889 S100141_02890 S100141_02890 S100141_02890 2641790 2642182 - 1%2C4-dihydroxy-2-naphthoyl-CoA hydrolase Hydrolase%3B Is not required for competence. Belongs to the thioesterase PaaI family%3B KEGG: eal:EAKF1_ch4366 1%2C4-dihydroxy-2-naphthoyl-CoA hydrolase gene gene2889 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02890 S100141_02891 S100141_02891 S100141_02891 2642196 2642834 - Transcriptional regulatory protein ComA Activator%3B Competence%3B Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Response regulator in the two-component regulatory system ComP/ComA involved in a major quorum response pathway that regulates the development of genetic competence. Regulates directly the expression of over 20 genes%2C including genes of the srfA operon%2C degQ%2C rapA%2C rapC%2C rapE%2C rapF%2C etc. Regulates indirectly%2C through the regulation of comK transcription%2C the expression of late competence genes%3B Contains 1 HTH luxR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2890 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02891 S100141_02892 S100141_02892 S100141_02892 2642921 2645221 - Histidine kinase ATP-binding%3B Cell membrane%3B Competence%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Sporulation%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Sensor in the two-component regulatory system ComP/ComA involved in a major quorum response pathway that regulates the development of genetic competence. Plays a role in sporulation%2C at least partly interchangeable with that of SpoIIJ. Probably activates ComA by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bao:BAMF_2968 two-component system%2C NarL family%2C sensor histidine kinase ComP gene gene2891 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02892 S100141_02893 S100141_02893 S100141_02893 2645223 2645396 - hypothetical protein gene gene2892 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02893 S100141_02894 S100141_02894 S100141_02894 2645400 2646281 - Competence regulatory protein ComQ Cell membrane%3B Competence%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Involved in the maturation of ComX%2C part of a major quorum-sensing system that regulates the development of genetic competence gene gene2893 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02894 S100141_02895 S100141_02895 S100141_02895 2646470 2646610 - Degradation enzyme regulation protein DegQ Stimulates the phosphotransfer from phospho-DegS to DegU. Affects protease and levansucrose production (By similarity)%3B Belongs to the DegQ family gene gene2894 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02895 S100141_02896 S100141_02896 S100141_02896 2646888 2647103 - hypothetical protein gene gene2895 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02896 S100141_02897 S100141_02897 S100141_02897 2647105 2647443 + uncharacterized protein gene gene2896 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02897 S100141_02898 S100141_02898 S100141_02898 2647486 2648706 - uncharacterized protein Contains 1 EAL domain gene gene2897 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02898 S100141_02899 S100141_02899 S100141_02899 2648885 2650354 - Nicotinate phosphoribosyltransferase Ligase%3B Pyridine nucleotide biosynthesis%3B Transferase%3B Catalyzes the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN)%3B Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP%3B Belongs to the NAPRTase family%3B KEGG: bli:BL02611 nicotinate phosphoribosyltransferase gene gene2898 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02899 S100141_02900 S100141_02900 S100141_02900 2650372 2650923 - putative isochorismatase family protein PncA Hydrolase%3B Belongs to the isochorismatase family gene gene2899 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02900 S100141_02901 S100141_02901 S100141_02901 2651108 2651509 - uncharacterized protein gene gene2900 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02901 S100141_02902 S100141_02902 S100141_02902 2651604 2651852 - uncharacterized protein gene gene2901 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02902 S100141_02903 S100141_02903 S100141_02903 2651926 2652147 - Spore germination protein-like protein YueG Belongs to the GerPA/GerPF family gene gene2902 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02903 S100141_02904 S100141_02904 S100141_02904 2652204 2653313 - UPF0118 membrane protein YueF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0118 (PerM) family gene gene2903 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02904 S100141_02905 S100141_02905 S100141_02905 2653502 2653936 + Putative HTH-type transcriptional regulator YwnA DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH rrf2-type DNA-binding domain gene gene2904 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02905 S100141_02906 S100141_02906 S100141_02906 2654190 2655002 + hypothetical protein gene gene2905 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02906 S100141_02907 S100141_02907 S100141_02907 2655149 2656612 + hypothetical protein gene gene2906 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02907 S100141_02908 S100141_02908 S100141_02908 2656609 2657139 - Putative phosphohydrolase YueE Hydrolase%3B Contains 1 HD domain gene gene2907 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02908 S100141_02909 S100141_02909 S100141_02909 2657276 2658007 - Benzil reductase ((S)-benzoin forming) Cytoplasm%3B NADP%3B Oxidoreductase%3B Reduces benzil stereospecifically to (S)-benzoin%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bli:BL02617 benzil reductase ((S)-benzoin forming) gene gene2908 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02909 S100141_02910 S100141_02910 S100141_02910 2658154 2658642 - hypothetical protein gene gene2909 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02910 S100141_02911 S100141_02911 S100141_02911 2658632 2661694 - Bacteriophage SPP1 adsorption protein YueB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Bacteriophage SPP1 receptor. Essential for the irreversible adsorption of the bacteriophage gene gene2910 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02911 S100141_02912 S100141_02912 S100141_02912 2661691 2666175 - Ftsk domain-containing protein YukB ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Contains 2 FtsK domains gene gene2911 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02912 S100141_02913 S100141_02913 S100141_02913 2666212 2667528 - uncharacterized protein Cell membrane%3B Coiled coil%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the EssB family gene gene2912 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02913 S100141_02914 S100141_02914 S100141_02914 2667543 2667782 - putative ubiquitin-like protein YukD gene gene2913 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02914 S100141_02915 S100141_02915 S100141_02915 2667863 2668159 - Virulence factor EsxA Secreted%3B Virulence%3B Virulence factor that is important for the establishment of infection in the host%3B Belongs to the ESAT-6 (esx) family gene gene2914 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02915 S100141_02916 S100141_02916 S100141_02916 2668492 2669901 - Sodium/alanine symporter AgcS Amino-acid transport%3B Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably functions as a sodium/L- and D-alanine symporter for alanine uptake%3B Belongs to the sodium:alanine (SAF) symporter family gene gene2915 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02916 S100141_02917 S100141_02917 S100141_02917 2670084 2671322 + Transcriptional activator AdeR Activator%3B DNA-binding%3B Sporulation%3B Transcription%3B Transcription regulation%3B Mediates ald expression in response to alanine availability and is important for normal sporulation in B. subtilis%3B Belongs to the CdaR family gene gene2916 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02917 S100141_02918 S100141_02918 S100141_02918 2671433 2672572 + NAD(P)(+) transhydrogenase (Re/Si-specific) NAD%3B Oxidoreductase%3B May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer%3B Belongs to the AlaDH/PNT family%3B KEGG: eco:b1603 NAD(P) transhydrogenase subunit alpha gene gene2917 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02918 S100141_02919 S100141_02919 S100141_02919 2672623 2672868 - hypothetical protein gene gene2918 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02919 S100141_02920 S100141_02920 S100141_02920 2672883 2673476 - putative oxidoreductase YuiH Metal-binding%3B Molybdenum%3B Oxidoreductase%3B KEGG: bli:BL05322 sulfoxide reductase catalytic subunit YedY%3B Acting on a sulfur group of donors gene gene2919 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02920 S100141_02921 S100141_02921 S100141_02921 2673579 2674175 + Putative biotin transporter BioYB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Putative biotin transporter%3B Belongs to the BioY family gene gene2920 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02921 S100141_02922 S100141_02922 S100141_02922 2674256 2675584 - Putative amino acid transporter YuiF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport. gene gene2921 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02922 S100141_02923 S100141_02923 S100141_02923 2675736 2677226 - Leucyl aminopeptidase Aminopeptidase%3B Cytoplasm%3B Hydrolase%3B Manganese%3B Metal-binding%3B Protease%3B Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides%3B Belongs to the peptidase M17 family%3B KEGG: bli:BL05323 leucyl aminopeptidase gene gene2922 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02923 S100141_02924 S100141_02924 S100141_02924 2677392 2677868 + putative membrane protein YuiD Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2923 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02924 S100141_02925 S100141_02925 S100141_02925 2677911 2678585 - uncharacterized protein Signal. gene gene2924 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02925 S100141_02926 S100141_02926 S100141_02926 2678711 2679040 - putative membrane protein YuiB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2925 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02926 S100141_02927 S100141_02927 S100141_02927 2679543 2680754 - NADH dehydrogenase FAD%3B Flavoprotein%3B Oxidoreductase%3B Belongs to the NADH dehydrogenase family%3B KEGG: bsu:BSU32100 NADH dehydrogenase gene gene2926 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02927 S100141_02928 S100141_02928 S100141_02928 2681099 2682097 + Thioredoxin-disulfide reductase FAD%3B Flavoprotein%3B NADP%3B Oxidoreductase%3B Belongs to the ferredoxin--NADP reductase type 2 family%3B KEGG: bsu:BSU32110 thioredoxin reductase (NADPH) gene gene2927 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02928 S100141_02929 S100141_02929 S100141_02929 2682132 2682332 - hypothetical protein gene gene2928 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02929 S100141_02930 S100141_02930 S100141_02930 2682475 2682699 + uncharacterized protein gene gene2929 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02930 S100141_02931 S100141_02931 S100141_02931 2682794 2683348 - DNA-3-methyladenine glycosylase I Contains 1 N-acetyltransferase domain%3B KEGG: bha:BH1453 DNA-3-methyladenine glycosylase I gene gene2930 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02931 S100141_02932 S100141_02932 S100141_02932 2683369 2683734 - Iron-sulfur cluster insertion protein ErpA Iron%3B Iron-sulfur%3B Metal-binding%3B Required for insertion of 4Fe-4S clusters for at least IspG%3B Belongs to the HesB/IscA family gene gene2931 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02932 S100141_02933 S100141_02933 S100141_02933 2683809 2684666 - Diaminopimelate epimerase Amino-acid biosynthesis%3B Cytoplasm%3B Disulfide bond%3B Isomerase%3B Lysine biosynthesis%3B Catalyzes the stereoinversion of LL-2%2C6- diaminoheptanedioate (L%2CL-DAP) to meso-diaminoheptanedioate (meso- DAP)%2C a precursor of L-lysine and an essential component of the bacterial peptidoglycan%3B Belongs to the diaminopimelate epimerase family%3B KEGG: bsu:BSU32170 diaminopimelate epimerase gene gene2932 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02933 S100141_02934 S100141_02934 S100141_02934 2684792 2686009 - putative transporter YutK Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the concentrative nucleoside transporter (CNT) (TC 2. A. 41) family gene gene2933 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02934 S100141_02935 S100141_02935 S100141_02935 2686166 2686402 - UPF0349 protein Belongs to the UPF0349 family gene gene2934 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02935 S100141_02936 S100141_02936 S100141_02936 2686674 2687741 + NADH dehydrogenase FAD%3B Flavoprotein%3B Oxidoreductase%3B Belongs to the NADH dehydrogenase family%3B KEGG: blh:BaLi_c34690 NADH dehydrogenase gene gene2935 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02936 S100141_02937 S100141_02937 S100141_02937 2687849 2688220 - Intracellular iron chaperone frataxin Cytoplasm%3B Ion transport%3B Iron%3B Iron transport%3B Metal-binding%3B Transport%3B Possible global iron distributor for the cell. Promotes the biosynthesis of iron-sulfur clusters by delivering Fe to the iron-sulfur cluster assembly scaffold protein SufU. In the presence of SufS and L-cysteine reconstitutes Fe-S clusters on SufU%2C which when further incubated with apo-aconitase (citB) reconstitutes aconitase activity. Able to reconstitute an Fe-S cluster on Thermotoga maritima IscU gene gene2936 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02937 S100141_02938 S100141_02938 S100141_02938 2688549 2688740 - hypothetical protein gene gene2937 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02938 S100141_02939 S100141_02939 S100141_02939 2688737 2689843 - Response regulator aspartate phosphatase Hydrolase%3B Protein phosphatase%3B Repeat%3B TPR repeat%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bli:BL02337 response regulator aspartate phosphatase K%3B Acting on ester bonds gene gene2938 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02939 S100141_02940 S100141_02940 S100141_02940 2690119 2690619 + Phenolic acid decarboxylase PadC Aromatic hydrocarbons catabolism%3B Decarboxylase%3B Detoxification%3B Lyase%3B Involved in the decarboxylation and detoxification of phenolic derivatives. It is able to catalyze the decarboxylation of ferulic%2C p-coumaric and caffeic acids%3B Belongs to the PadC family%3B KEGG: bli:BL02117 phenolic acid decarboxylase%3B Carboxy-lyases gene gene2939 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02940 S100141_02941 S100141_02941 S100141_02941 2690629 2690895 - hypothetical protein gene gene2940 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02941 S100141_02942 S100141_02942 S100141_02942 2691006 2691332 - Putative disulfide oxidoreductase YuzD Disulfide bond%3B Redox-active center. gene gene2941 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02942 S100141_02943 S100141_02943 S100141_02943 2691525 2691764 + Putative nitrogen fixation protein YutI Nitrogen fixation%3B May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins%3B Belongs to the NifU family gene gene2942 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02943 S100141_02944 S100141_02944 S100141_02944 2692001 2693962 - Acylaminoacyl-peptidase Hydrolase%3B Protease%3B Serine protease%3B Belongs to the peptidase S9B family%3B KEGG: bce:BC0192 acylaminoacyl-peptidase gene gene2943 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02944 S100141_02945 S100141_02945 S100141_02945 2694069 2694989 - Homoserine kinase Amino-acid biosynthesis%3B ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Threonine biosynthesis%3B Transferase%3B Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate%3B Belongs to the GHMP kinase family. Homoserine kinase subfamily%3B KEGG: bsu:BSU32240 homoserine kinase gene gene2944 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02945 S100141_02946 S100141_02946 S100141_02946 2694986 2696053 - Threonine synthase Amino-acid biosynthesis%3B Lyase%3B Pyridoxal phosphate%3B Threonine biosynthesis%3B Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine%3B Belongs to the threonine synthase family%3B KEGG: bsl:A7A1_2331 threonine synthase gene gene2945 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02946 S100141_02947 S100141_02947 S100141_02947 2696044 2697345 - Homoserine dehydrogenase Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Isoleucine biosynthesis%3B Methionine biosynthesis%3B NADP%3B Oxidoreductase%3B Threonine biosynthesis%3B Belongs to the homoserine dehydrogenase family%3B Contains 1 ACT domain%3B KEGG: seds:AAY24_06030 homoserine dehydrogenase gene gene2946 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02947 S100141_02948 S100141_02948 gyaR gyaR 2697579 2698541 - Glyoxylate reductase Cytoplasm%3B NAD%3B Oxidoreductase%3B Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GyaR subfamily%3B KEGG: bmq:BMQ_4977 glyoxylate reductase gene gene2947 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02948 S100141_02949 S100141_02949 S100141_02949 2698631 2699653 - Endospore coat-associated protein YutH Membrane%3B Sporulation%3B Involved in sporulation%3B Belongs to the CotS family gene gene2948 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02949 S100141_02950 S100141_02950 S100141_02950 2699804 2700286 + Phosphatidylglycerophosphatase To B. subtilis YutG%3B KEGG: bpu:BPUM_1917 phosphatidylglycerophosphatase A gene gene2949 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02950 S100141_02951 S100141_02951 S100141_02951 2700332 2701102 - 4-nitrophenylphosphatase Hydrolase%3B Belongs to the HAD-like hydrolase superfamily%3B KEGG: bsu:BSU32290 4-nitrophenyl phosphatase gene gene2950 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02951 S100141_02952 S100141_02952 S100141_02952 2701122 2701562 - UPF0331 protein YutE Belongs to the UPF0331 family gene gene2951 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02952 S100141_02953 S100141_02953 S100141_02953 2701590 2701865 - uncharacterized protein Disulfide bond. gene gene2952 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02953 S100141_02954 S100141_02954 S100141_02954 2701968 2702591 + putative lipoprotein YutC Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal. gene gene2953 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02954 S100141_02955 S100141_02955 S100141_02955 2702645 2703541 - Lipoyl synthase 4Fe-4S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B S-adenosyl-L-methionine%3B Transferase%3B Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes%2C thereby converting the octanoylated domains into lipoylated derivatives%3B Belongs to the radical SAM superfamily. Lipoyl synthase family%3B KEGG: bsu:BSU32330 lipoic acid synthetase gene gene2954 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02955 S100141_02956 S100141_02956 S100141_02956 2703794 2704774 + L-Ala--D-Glu endopeptidase Cell cycle%3B Cell wall biogenesis/degradation%3B Differentiation%3B Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Signal%3B Sporulation%3B Zinc%3B L-Ala--D-Glu endopeptidase involved in production of single L-alanine side chains from tetrapeptides in the spore cortex peptidoglycan. Therefore%2C is required for the endospore cortex maturation%3B Belongs to the peptidase M23B family gene gene2955 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02956 S100141_02957 S100141_02957 S100141_02957 2704823 2704936 - hypothetical protein gene gene2956 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02957 S100141_02958 S100141_02958 S100141_02958 2704933 2706462 - putative sodium-dependent transporter YhdH Cell membrane%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Putative sodium-dependent transporter%3B Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2. A. 22) family gene gene2957 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02958 S100141_02959 S100141_02959 S100141_02959 2706648 2707421 - Sporulation protein YunB Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Required for sporulation gene gene2958 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02959 S100141_02960 S100141_02960 S100141_02960 2707489 2707794 - uncharacterized protein gene gene2959 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02960 S100141_02961 S100141_02961 S100141_02961 2707872 2709227 - 5'-nucleotidase Coiled coil%3B Hydrolase%3B Metal-binding%3B Belongs to the metallophosphoesterase superfamily%3B KEGG: llm:llmg_0192 5'-nucleotidase gene gene2960 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02961 S100141_02962 S100141_02962 S100141_02962 2709247 2710068 - UPF0721 transmembrane protein YunE Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0721 family gene gene2961 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02962 S100141_02963 S100141_02963 S100141_02963 2710086 2710937 - UPF0759 protein YunF Belongs to the UPF0759 family gene gene2962 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02963 S100141_02964 S100141_02964 S100141_02964 2711069 2711602 - putative membrane protein YmcC Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2963 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02964 S100141_02965 S100141_02965 S100141_02965 2711693 2712277 + HTH-type transcriptional regulator PksA DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcriptional regulation of the polyketide synthase operon. Contains 1 HTH tetR-type DNA-binding domain gene gene2964 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02965 S100141_02966 S100141_02966 S100141_02966 2712466 2712687 - hypothetical protein gene gene2965 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02966 S100141_02967 S100141_02967 S100141_02967 2713196 2714422 - Purine catabolism protein PucG Aminotransferase%3B Purine metabolism%3B Pyridoxal phosphate%3B Transferase%3B Could encode ureidoglycolase or L-alanine:glyoxylate aminotransferase%2C or perhaps both activities%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bli:BL02152 (S)-ureidoglycine-glyoxylate aminotransferase%3B Transaminases gene gene2966 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02967 S100141_02968 S100141_02968 S100141_02968 2714438 2715691 - Allantoate deiminase Hydrolase%3B Metal-binding%3B Purine metabolism%3B Zinc%3B Involved in the anaerobic utilization of allantoin. Converts allantoate to (S)-ureidoglycolate and ammonia%3B Belongs to the peptidase M20 family%3B KEGG: bli:BL02153 allantoate deiminase gene gene2967 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02968 S100141_02969 S100141_02969 S100141_02969 2715856 2717454 + Purine catabolism regulatory protein Activator%3B DNA-binding%3B Purine metabolism%3B Repressor%3B Transcription%3B Transcription regulation%3B Activates the expression of pucFG%2C pucH%2C pucI%2C pucJKLM and guaD%2C while it represses pucABCDE and its own expression%3B Belongs to the CdaR family gene gene2968 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02969 S100141_02970 S100141_02970 S100141_02970 2717557 2718753 - Multidrug resistance protein Antibiotic resistance%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Energy-dependent efflux pump responsible for decreased drug accumulation in multi-drug-resistant cells. Probably uses a transmembrane proton gradient as the energy source. Causes the efflux of a variety of toxic substances%2C including such structurally diverse compounds as ethidium bromide%2C rhodamine and acridine dyes%2C tetraphenylphosphonium%2C puromycin%2C chloramphenicol%2C doxorubicin%2C and fluoroquinolone antibiotics. Belongs to the major facilitator superfamily. TCR/Tet family gene gene2969 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02970 S100141_02971 S100141_02971 S100141_02971 2718932 2720338 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B To E. coli YfcC and H. influenzae HI_0594 gene gene2970 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02971 S100141_02972 S100141_02972 S100141_02972 2720749 2721315 + Anthranilate phosphoribosyltransferase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Glycosyltransferase%3B Magnesium%3B Metal-binding%3B Transferase%3B Tryptophan biosynthesis%3B Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)%3B Belongs to the anthranilate phosphoribosyltransferase family%3B KEGG: blh:BaLi_c35040 anthranilate phosphoribosyltransferase%3B overlaps another CDS with the same product name gene gene2971 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02972 S100141_02973 S100141_02973 S100141_02973 2721279 2721626 + Anthranilate phosphoribosyltransferase KEGG: blh:BaLi_c35040 anthranilate phosphoribosyltransferase%3B overlaps another CDS with the same product name gene gene2972 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02973 S100141_02974 S100141_02974 S100141_02974 2721706 2722518 + Extracellular ribonuclease Hydrolase%3B Nuclease%3B Secreted%3B Signal%3B Mg(2+)-activated ribonuclease which hydrolyzes RNA apparently nonspecifically into oligonucleotides with 5'-terminal phosphate gene gene2973 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02974 S100141_02975 S100141_02975 ygeS ygeS 2722809 2723648 - Xanthine dehydrogenase KEGG: bce:BC3167 xanthine dehydrogenase molybdenum-binding subunit gene gene2974 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02975 S100141_02976 S100141_02976 dadA dadA 2723849 2724970 - D-arginine dehydrogenase FAD%3B Flavoprotein%3B Oxidoreductase%3B Belongs to the DadA oxidoreductase family%3B KEGG: bsu:BSU32630 D-amino-acid dehydrogenase gene gene2975 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02976 S100141_02977 S100141_02977 S100141_02977 2725036 2725896 - hypothetical protein gene gene2976 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02977 S100141_02978 S100141_02978 S100141_02978 2725927 2726310 - hypothetical protein gene gene2977 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02978 S100141_02979 S100141_02979 S100141_02979 2726594 2726767 - hypothetical protein gene gene2978 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02979 S100141_02980 S100141_02980 S100141_02980 2726898 2728013 - Response regulator aspartate phosphatase J Hydrolase%3B Protein phosphatase%3B Repeat%3B TPR repeat%3B Belongs to the RAP family%3B Contains 5 TPR repeats%3B KEGG: bli:BL02161 response regulator aspartate phosphatase I%3B Acting on ester bonds gene gene2979 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02980 S100141_02981 S100141_02981 S100141_02981 2728460 2729857 - FeS cluster assembly protein SufB The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake from extracellular iron chelators under iron limitation (By similarity)%3B Belongs to the UPF0051 (ycf24) family gene gene2980 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02981 S100141_02982 S100141_02982 S100141_02982 2729876 2730322 - Zinc-dependent sulfurtransferase SufU Metal-binding%3B Transferase%3B Zinc%3B Its function is controversial. Has been generally assumed to be an iron-sulfur cluster assembly scaffold protein (PubMed:20097860%2C PubMed:21236255)%2C but more recent evidence suggest it is a sulfurtransferase rather than a scaffold assembly protein (PubMed:24321018). Has been shown to bind low levels of a labile%2C air-sensitive Fe-S cluste%3B this can be assembled under anaerobic conditions from FeCl(3) and Li(2)S. Has been shown to be able to transfer this Fe-S cluster to an acceptor protein. Stimulates the cysteine desulfurase activity of SufS%2C for which it acts as a second substrate. Alkylation eliminates its ability to stimulate SufS. A mixture of SufS%2C SufU%2C Fra and L-cysteine is able to reconstitute Fe-S clusters on apo-aconitase (citB)%2C reconstituting aconitase activity%3B Belongs to the NifU family gene gene2981 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02982 S100141_02983 S100141_02983 sufS sufS 2730312 2731532 - Cysteine desulfurase Cytoplasm%3B Lyase%3B Pyridoxal phosphate%3B Transferase%3B Cysteine desulfurases mobilize the sulfur from L- cysteine to yield L-alanine%2C an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon%2C which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro%2C that mobilizes selenium from L-selenocysteine. Selenocysteine lyase activity is however unsure in vivo%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily%3B KEGG: bli:BL02164 cysteine desulfurase / selenocysteine lyase gene gene2982 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02983 S100141_02984 S100141_02984 S100141_02984 2731532 2732845 - FeS cluster assembly protein SufD The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake from extracellular iron chelators under iron limitation (By similarity)%3B Belongs to the UPF0051 (ycf24) family gene gene2983 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02984 S100141_02985 S100141_02985 S100141_02985 2732863 2733648 - Vegetative protein 296 ATP-binding%3B Nucleotide-binding%3B Transport%3B Belongs to the ABC transporter superfamily. Ycf16 family%3B Contains 1 ABC transporter domain gene gene2984 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02985 S100141_02986 S100141_02986 S100141_02986 2733877 2734812 - Cadmium%2C cobalt and zinc/H(+)-K(+) antiporter Cadmium%3B Cell membrane%3B Cobalt%3B Cobalt transport%3B Ion transport%3B Membrane%3B Potassium%3B Potassium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Zinc%3B Zinc transport%3B Involved in divalent cation and potassium homeostasis in the cell. Catalyzes the active efflux of zinc%2C cadmium and cobalt%2C in exchange for potassium and H(+) ions (By similarity)%3B Belongs to the cation diffusion facilitator (CDF) transporter (TC 2. A. 4) family. SLC30A subfamily gene gene2985 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02986 S100141_02987 S100141_02987 S100141_02987 2735233 2735601 - 4-carboxymuconolactone decarboxylase KEGG: bca:BCE_2858 4-carboxymuconolactone decarboxylase gene gene2986 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02987 S100141_02988 S100141_02988 S100141_02988 2735708 2736538 - Methionine-binding lipoprotein MetQ Amino-acid transport%3B Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B Part of the ABC transporter complex MetNPQ involved in methionine import. Binds the methionine and transfers it to the membrane-bound permease. It has also been shown to be involved in methionine sulfoxide transport (Probable)%3B Belongs to the NlpA lipoprotein family gene gene2987 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02988 S100141_02989 S100141_02989 S100141_02989 2736552 2737220 - Methionine import system permease protein MetP Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex MetNPQ involved in methionine import. Responsible for the translocation of the substrate across the membrane (Probable). It has also been shown to be involved in methionine sulfoxide transport%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2988 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02989 S100141_02990 S100141_02990 S100141_02990 2737213 2738238 - Lipoprotein-releasing system ATP-binding protein LolD ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins%2C from the inner membrane to the periplasmic chaperone%2C LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner%3B Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3. A. 1. 125) family%3B Contains 1 ABC transporter domain%3B KEGG: yen:YE1199 macrolide transport system ATP-binding/permease protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene2989 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02990 S100141_02991 S100141_02991 S100141_02991 2738646 2738993 - uncharacterized protein gene gene2990 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02991 S100141_02992 S100141_02992 S100141_02992 2739115 2739423 - Thioredoxin-like protein YusE Disulfide bond%3B Redox-active center%3B Contains 1 thioredoxin domain gene gene2991 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02992 S100141_02993 S100141_02993 S100141_02993 2739449 2739793 - uncharacterized protein Contains 1 Toprim domain gene gene2992 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02993 S100141_02994 S100141_02994 S100141_02994 2739856 2740092 - uncharacterized protein gene gene2993 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02994 S100141_02995 S100141_02995 S100141_02995 2740146 2740529 - Glycine cleavage system H protein Lipoyl%3B The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein%3B Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate%3B Belongs to the GcvH family%3B Contains 1 lipoyl-binding domain gene gene2994 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02995 S100141_02996 S100141_02996 S100141_02996 2740591 2740947 - Arsenate reductase (glutaredoxin) Oxidoreductase%3B Belongs to the ArsC family%3B KEGG: bli:BL02177 arsenate reductase gene gene2995 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02996 S100141_02997 S100141_02997 S100141_02997 2741067 2742851 - putative acyl-CoA dehydrogenase FAD%3B Fatty acid metabolism%3B Flavoprotein%3B Lipid degradation%3B Lipid metabolism%3B Oxidoreductase%3B Involved in the degradation of long-chain fatty acids. Belongs to the acyl-CoA dehydrogenase family%3B KEGG: bcl:ABC2988 null%3B With other acceptors gene gene2996 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02997 S100141_02998 S100141_02998 atoB atoB 2742871 2744046 - Acetyl-CoA C-acetyltransferase Acyltransferase%3B Fatty acid metabolism%3B Lipid degradation%3B Lipid metabolism%3B Transferase%3B Involved in the degradation of long-chain fatty acids. Belongs to the thiolase family%3B KEGG: spe:Spro_4857 acetyl-CoA C-acetyltransferase gene gene2997 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02998 S100141_02999 S100141_02999 fadN fadN 2744058 2746448 - 3-hydroxyacyl-CoA dehydrogenase Fatty acid metabolism%3B Lipid degradation%3B Lipid metabolism%3B NAD%3B Oxidoreductase%3B Involved in the degradation of long-chain fatty acids. Belongs to the 3-hydroxyacyl-CoA dehydrogenase family%3B KEGG: bsu:BSU32840 3-hydroxyacyl-CoA dehydrogenase gene gene2998 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_02999 S100141_03000 S100141_03000 S100141_03000 2746658 2746819 + hypothetical protein gene gene2999 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03000 S100141_03001 S100141_03001 S100141_03001 2746896 2747144 + uncharacterized protein gene gene3000 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03001 S100141_03002 S100141_03002 S100141_03002 2747155 2747496 + uncharacterized protein gene gene3001 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03002 S100141_03003 S100141_03003 S100141_03003 2747526 2747777 - uncharacterized protein Coiled coil. gene gene3002 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03003 S100141_03004 S100141_03004 S100141_03004 2747778 2748518 - hypothetical protein gene gene3003 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03004 S100141_03005 S100141_03005 S100141_03005 2748511 2749329 - Iron-chelate-transporting ATPase ATP-binding%3B Cell membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Nucleotide-binding%3B Transport%3B Provides the ATPase subunit for at least 2 ABC transporter complexe%3B YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen%2C arthrobactin and corprogen (Probable)%2C and FeuABC/YusV involved in import of the catecholate siderophores bacillibactin and enterobactin (Probable). Probably responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: bsu:BSU32940 iron complex transport system ATP-binding protein gene gene3004 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03005 S100141_03006 S100141_03006 S100141_03006 2749347 2750402 - putative siderophore transport system permease protein YfhA Cell membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen%2C arthrobactin and corprogen%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene3005 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03006 S100141_03007 S100141_03007 S100141_03007 2750399 2751400 - putative siderophore transport system permease protein YfiZ Cell membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Signal%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen%2C arthrobactin and corprogen%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene3006 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03007 S100141_03008 S100141_03008 S100141_03008 2751553 2752530 + putative siderophore-binding lipoprotein YfiY Cell membrane%3B Cytoplasm%3B Ion transport%3B Iron%3B Iron transport%3B Lipoprotein%3B Membrane%3B Palmitate%3B Phosphoprotein%3B Signal%3B Transport%3B Part of the ABC transporter complex YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen%2C arthrobactin and corprogen. Binds the siderophores and delivers them to the surface of YfiZ/YfhA (Probable)%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene3007 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03008 S100141_03009 S100141_03009 S100141_03009 2752570 2753016 - uncharacterized protein Coiled coil%3B Signal. gene gene3008 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03009 S100141_03010 S100141_03010 S100141_03010 2753094 2754878 - Oligoendopeptidase F%2C plasmid Hydrolase%3B Metal-binding%3B Metalloprotease%3B Plasmid%3B Protease%3B Zinc%3B Hydrolyzes peptides containing between 7 and 17 amino acids with a rather wide specificity. Belongs to the peptidase M3B family%3B KEGG: gbm:Gbem_1295 oligoendopeptidase F%3B Metalloendopeptidases gene gene3009 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03010 S100141_03011 S100141_03011 S100141_03011 2754990 2756144 - Serine-type D-Ala-D-Ala carboxypeptidase Carboxypeptidase%3B Cell shape%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Membrane%3B Peptidoglycan synthesis%3B Protease%3B Signal%3B Sporulation%3B Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. Required specifically for the synthesis of the spore form of peptidoglycan (cortex). Belongs to the peptidase S11 family%3B KEGG: bli:BL05330 D-alanyl-D-alanine carboxypeptidase gene gene3010 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03011 S100141_03012 S100141_03012 S100141_03012 2756285 2757127 + 3-oxoacyl-[acyl-carrier-protein] reductase Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: aad:TC41_1190 3-oxoacyl-(acyl-carrier protein) reductase gene gene3011 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03012 S100141_03013 S100141_03013 S100141_03013 2757222 2757686 + Metalloregulation DNA-binding stress protein DNA-binding%3B Stress response%3B Forms highly stable%2C multimeric protein-DNA complexes which accumulate in stationary-phase cells and protect against oxidative killing. Belongs to the Dps family gene gene3012 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03013 S100141_03014 S100141_03014 S100141_03014 2757722 2759092 - Peptidase Do Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Serine protease%3B Stress response%3B Transmembrane%3B Transmembrane helix%3B Degrades abnormal exported proteins and responsible for the propeptide processing of a natural pro-protein and for the maturation of a native protein. It also plays a prominent role in stress (heat shock%2C ethanol%2C puromycin and NaCl) resistance during active exponential growth (Probable)%3B Belongs to the peptidase S1C family%3B Contains 1 PDZ (DHR) domain%3B KEGG: bli:BL00734 serine protease Do gene gene3013 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03014 S100141_03015 S100141_03015 S100141_03015 2759331 2760005 + Transcriptional regulatory protein CssR Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3014 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03015 S100141_03016 S100141_03016 cssS cssS 2760002 2761348 + Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress. Required for the transcription of htrA. Could detect misfolded proteins at the membrane-cell wall interface and then activate CssR by phosphorylation%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: bli:BL00749 two-component system%2C OmpR family%2C sensor histidine kinase CssS gene gene3015 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03016 S100141_03017 S100141_03017 S100141_03017 2761372 2761536 - uncharacterized protein gene gene3016 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03017 S100141_03018 S100141_03018 S100141_03018 2761655 2762608 + putative HTH-type transcriptional regulator YuxN DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH tetR-type DNA-binding domain gene gene3017 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03018 S100141_03019 S100141_03019 fumC fumC 2762654 2764042 - Fumarate hydratase Allosteric enzyme%3B Cytoplasm%3B Lyase%3B Tricarboxylic acid cycle%3B Catalyzes the reversible addition of water to fumarate to give L-malate%3B Belongs to the class-II fumarase/aspartase family. Fumarase subfamily%3B KEGG: hin:HI1398 fumarate hydratase%2C class II gene gene3018 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03019 S100141_03020 S100141_03020 S100141_03020 2764126 2764293 - uncharacterized protein gene gene3019 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03020 S100141_03021 S100141_03021 S100141_03021 2764417 2765472 + Spore germination protein A1 Cell membrane%3B Germination%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Forms a complex at the inner spore membrane which acts as a receptor for L-alanine%2C thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of GerD and GerK gene products (fructose and glucose receptors%2C respectively)%2C but the response is improved in their presence. Belongs to the GerABKA family gene gene3020 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03021 S100141_03022 S100141_03022 S100141_03022 2765827 2766927 + Spore germination protein A2 Amino-acid transport%3B Cell membrane%3B Germination%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the germinative response to L-alanine. Could be an amino acid transporter. Forms a complex at the inner spore membrane which acts as a receptor for L-alanine%2C thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors%2C respectively)%2C but the response is improved in their presence. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2. A. 3. 9) family gene gene3021 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03022 S100141_03023 S100141_03023 S100141_03023 2766924 2768045 + Spore germination protein B3 Cell membrane%3B Germination%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Involved in the response to the germinative mixture of L-asparagine%2C glucose%2C fructose and potassium ions (AGFK). Cannot stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors respectively). Belongs to the GerABKC lipoprotein family gene gene3022 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03023 S100141_03024 S100141_03024 S100141_03024 2768107 2768472 + hypothetical protein gene gene3023 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03024 S100141_03025 S100141_03025 S100141_03025 2768509 2769144 - Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon Chemotaxis%3B Cytoplasm%3B Hydrolase%3B Phosphoprotein%3B Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene3024 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03025 S100141_03026 S100141_03026 liaS liaS 2769148 2770212 - Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system LiaS/LiaR probably involved in response to a subset of cell wall-active antibiotics that interfere with the lipid II cycle in the cytoplasmic membrane (bacitracin%2C nisin%2C ramoplanin and vancomycin). Seems also involved in response to cationic antimicrobial peptides and secretion stress. Activates probably LiaR by phosphorylation%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: bli:BL00729 two-component system%2C NarL family%2C sensor histidine kinase LiaS gene gene3025 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03026 S100141_03027 S100141_03027 S100141_03027 2770209 2770940 - Protein LiaF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3026 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03027 S100141_03028 S100141_03028 S100141_03028 2770971 2771834 - hypothetical protein gene gene3027 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03028 S100141_03029 S100141_03029 S100141_03029 2771940 2772623 - Protein LiaH Coiled coil%3B Belongs to the PspA/IM30 family gene gene3028 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03029 S100141_03030 S100141_03030 S100141_03030 2772644 2773030 - Protein LiaI Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3029 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03030 S100141_03031 S100141_03031 S100141_03031 2773203 2774156 - Pectinesterase Aspartyl esterase%3B Disulfide bond%3B Glycoprotein%3B Hydrolase%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Acts in the modification of cell walls via demethylesterification of cell wall pectin%3B In the N-terminal sectio%3B belongs to the PMEI family%3B In the C-terminal sectio%3B belongs to the pectinesterase family%3B KEGG: bli:BL00724 pectinesterase gene gene3030 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03031 S100141_03032 S100141_03032 mmaB mmaB 2774287 2774865 - Cob(I)yrinic acid a%2Cc-diamide adenosyltransferase ATP-binding%3B Cobalamin biosynthesis%3B Cytoplasm%3B Nucleotide-binding%3B Porphyrin biosynthesis%3B Transferase%3B Belongs to the Cob(I)alamin adenosyltransferase family%3B KEGG: bsu:BSU33150 cob(I)alamin adenosyltransferase gene gene3031 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03032 S100141_03033 S100141_03033 S100141_03033 2775051 2775797 + 3-oxoacyl-[acyl-carrier-protein] reductase NAD%3B Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: mbat:BN1208_0787 3-oxoacyl-(acyl-carrier protein) reductase gene gene3032 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03033 S100141_03034 S100141_03034 pdxA pdxA 2775835 2776053 - 4-hydroxythreonine-4-phosphate dehydrogenase Cobalt%3B Cytoplasm%3B Magnesium%3B Metal-binding%3B NAD%3B NADP%3B Oxidoreductase%3B Pyridoxine biosynthesis%3B Zinc%3B Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)%3B Belongs to the PdxA family%3B KEGG: eco:b0052 4-hydroxythreonine-4-phosphate dehydrogenase gene gene3033 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03034 S100141_03035 S100141_03035 S100141_03035 2776571 2777740 - Alcohol dehydrogenase NAD%3B Oxidoreductase%3B Long-chain alkyl alcohol dehydrogenase that can oxidize a broad range of alkyl alcohols from ethanol to 1-triacontanol (C2 to C30) as well as 1%2C3-propanediol and acetaldehyde. The best substrate is ethanol. Also oxidizes glycerol%3B Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: bld:BLi03502 alcohol dehydrogenase gene gene3034 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03035 S100141_03036 S100141_03036 S100141_03036 2777745 2778647 - 4-hydroxy-tetrahydrodipicolinate synthase Amino-acid biosynthesis%3B Cytoplasm%3B Diaminopimelate biosynthesis%3B Lyase%3B Lysine biosynthesis%3B Schiff base%3B Catalyzes the condensation of (S)-aspartate-beta- semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)%3B Belongs to the DapA family%3B KEGG: msu:MS0282 4-hydroxy-tetrahydrodipicolinate synthase gene gene3035 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03036 S100141_03037 S100141_03037 ccmA ccmA 2778824 2780107 - Heme-transporting ATPase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Repeat%3B Sugar transport%3B Transport%3B Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose%2C galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Carbohydrate importer 2 (CUT2) (TC 3. A. 1. 2) family%3B Contains 2 ABC transporter domains%3B KEGG: pao:Pat9b_2799 heme exporter protein A gene gene3036 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03037 S100141_03038 S100141_03038 S100141_03038 2780100 2781164 - putative ABC transporter permease protein YvrB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably part of an ABC transporter complex. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene3037 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03038 S100141_03039 S100141_03039 S100141_03039 2781127 2782077 - putative ABC transporter substrate-binding lipoprotein YvrC Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Probably part of an ABC transporter complex%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene3038 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03039 S100141_03040 S100141_03040 S100141_03040 2782457 2783137 + Nta operon transcriptional regulator DNA-binding%3B Transcription%3B Transcription regulation%3B Probable regulator for the expression of the NTA monooxygenase subunits. Contains 1 HTH gntR-type DNA-binding domain gene gene3039 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03040 S100141_03041 S100141_03041 S100141_03041 2783236 2784027 + 3-oxoacyl-[acyl-carrier-protein] reductase Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: pjd:Pjdr2_3073 3-oxoacyl-(acyl-carrier protein) reductase gene gene3040 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03041 S100141_03042 S100141_03042 S100141_03042 2784070 2784765 - uncharacterized protein Contains 1 MOSC domain gene gene3041 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03042 S100141_03043 S100141_03043 S100141_03043 2784926 2785834 + Hydrogen peroxide-inducible protein activator Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase%3B Contains 1 HTH lysR-type DNA-binding domain gene gene3042 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03043 S100141_03044 S100141_03044 S100141_03044 2785872 2787182 - Alpha-L-rhamnosidase Alginate biosynthesis%3B Calcium%3B Isomerase%3B Repeat%3B Secreted%3B Converts beta-D-mannuronic acid (M) to alpha-L-guluronic acid (G). Has both epimerase and lyase activities. Contributes to abortive encystment by degrading the coat from inside the cyst. Important for cyst germination. Belongs to the D-mannuronate C5-epimerase family%3B Contains 8 hemolysin-type calcium-binding repeats%3B Contains 9 PbH1 repeats%3B KEGG: vba:IMCC26134_08560 alpha-L-rhamnosidase gene gene3043 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03044 S100141_03045 S100141_03045 uxaA uxaA 2787196 2788686 - Altronate dehydratase Iron%3B Lyase%3B Manganese%3B Catalyzes the dehydration of D-altronate%3B Belongs to the UxaA family%3B KEGG: bli:BL00712 altronate hydrolase gene gene3044 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03045 S100141_03046 S100141_03046 uxaB uxaB 2788686 2790155 - Tagaturonate reductase NAD%3B Oxidoreductase%3B Belongs to the mannitol dehydrogenase family. UxaB subfamily%3B KEGG: bli:BL00711 tagaturonate reductase gene gene3045 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03046 S100141_03047 S100141_03047 S100141_03047 2790216 2791214 - Catabolite control protein A Activator%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA)%2C which ensures optimal energy usage under diverse conditions%3B Contains 1 HTH lacI-type DNA-binding domain gene gene3046 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03047 S100141_03048 S100141_03048 S100141_03048 2791294 2792682 - putative symporter YjmB Cell membrane%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the sodium:galactoside symporter (TC 2. A. 2) family gene gene3047 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03048 S100141_03049 S100141_03049 uxaC uxaC 2792718 2794139 - Glucuronate isomerase Isomerase%3B Belongs to the uronate isomerase family%3B KEGG: eco:b3092 glucuronate isomerase gene gene3048 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03049 S100141_03050 S100141_03050 S100141_03050 2794316 2796073 - Sensor histidine kinase YvrG ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA%2C wapA- yxxG%2C dltABCDE%2C sunA%2C sunT-bdbA-yolJ-bdbB%2C sigO-rsoA%2C and sigX- rsiX)%2C and negatively regulates the lytABC operon. Probably activates YvrH by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: ban:BA_1118 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene3049 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03050 S100141_03051 S100141_03051 S100141_03051 2796070 2796798 - Transcriptional regulatory protein YvrH Activator%3B Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Repressor%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA%2C wapA- yxxG%2C dltABCDE%2C sunA%2C sunT-bdbA-yolJ-bdbB%2C sigO-rsoA%2C and sigX- rsiX)%2C and negatively regulates the lytABC operon%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3050 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03051 S100141_03052 S100141_03052 S100141_03052 2797022 2797834 - Iron-chelate-transporting ATPase ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Phosphate transport%3B Transport%3B Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphate importer (TC 3. A. 1. 7) family%3B Contains 1 ABC transporter domain%3B KEGG: eca:ECA1073 iron complex transport system ATP-binding protein gene gene3051 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03052 S100141_03053 S100141_03053 S100141_03053 2797853 2798866 - putative siderophore transport system permease protein YfhA Cell membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen%2C arthrobactin and corprogen%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene3052 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03053 S100141_03054 S100141_03054 S100141_03054 2798866 2799930 - Achromobactin transport system permease protein CbrB Cell inner membrane%3B Cell membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system CbrABCD for uptake of the siderophore achromobactin. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene3053 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03054 S100141_03055 S100141_03055 S100141_03055 2800086 2801489 - Putative arginine/ornithine antiporter Amino-acid transport%3B Antiport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene3054 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03055 S100141_03056 S100141_03056 S100141_03056 2801943 2802083 - Small%2C acid-soluble spore protein J Sporulation. gene gene3055 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03056 S100141_03057 S100141_03057 S100141_03057 2802323 2802793 + uncharacterized protein Cell membrane%3B Membrane%3B Signal%3B Transmembrane%3B Transmembrane helix%3B To E. coli YdjM gene gene3056 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03057 S100141_03058 S100141_03058 S100141_03058 2802893 2804752 + Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase Cell membrane%3B Manganese%3B Membrane%3B Metal-binding%3B Secreted%3B Transmembrane%3B Transmembrane helix%3B Belongs to the LTA synthase family%3B KEGG: baci:B1NLA3E_11025 lipoteichoic acid synthase gene gene3057 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03058 S100141_03059 S100141_03059 S100141_03059 2804954 2806405 + Multidrug export protein Antibiotic resistance%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the tripartite efflux system EmrAB-TolC%2C which confers resistance to antibiotics%3B Belongs to the major facilitator superfamily. EmrB family gene gene3058 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03059 S100141_03060 S100141_03060 dkgA dkgA 2806445 2807284 - 2%2C5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) NADP%3B Oxidoreductase%3B Reduces glyoxal and methylglyoxal. Is not involved in the vitamin B6 biosynthesis%3B Belongs to the aldo/keto reductase family%3B KEGG: yfr:AW19_2489 2%2C5-diketo-D-gluconate reductase A gene gene3059 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03060 S100141_03061 S100141_03061 scrK scrK 2807374 2808234 - Fructokinase ATP-binding%3B Carbohydrate metabolism%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Polysaccharide degradation%3B Transferase%3B Zinc%3B Seems to be involved in the degradation of glucomannan%3B Belongs to the ROK (NagC/XylR) family%3B KEGG: bli:BL00700 fructokinase gene gene3060 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03061 S100141_03062 S100141_03062 kynU kynU 2808501 2809625 + Kynureninase Aminotransferase%3B Pyridoxal phosphate%3B Transferase%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: msv:Mesil_0484 kynureninase gene gene3061 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03062 S100141_03063 S100141_03063 S100141_03063 2809705 2810115 + hypothetical protein gene gene3062 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03063 S100141_03064 S100141_03064 S100141_03064 2810121 2812451 - DNA helicase ATP-binding%3B Coiled coil%3B Cytoplasm%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Catalyzes the unwinding of duplex DNA in the 3' to 5' directio%3B this reaction is dependent on the hydrolysis of ATP%3B Belongs to the helicase family. UvrD subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B KEGG: bli:BL00699 DNA helicase II / ATP-dependent DNA helicase PcrA gene gene3063 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03064 S100141_03065 S100141_03065 S100141_03065 2812630 2813238 - UPF0126 membrane protein YvgT Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0126 family gene gene3064 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03065 S100141_03066 S100141_03066 S100141_03066 2813363 2813713 + UPF0157 protein Belongs to the UPF0157 (GrpB) family gene gene3065 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03066 S100141_03067 S100141_03067 S100141_03067 2813885 2813977 + hypothetical protein gene gene3066 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03067 S100141_03068 S100141_03068 S100141_03068 2813986 2814471 - hypothetical protein gene gene3067 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03068 S100141_03069 S100141_03069 S100141_03069 2814578 2814991 - Disulfide bond formation protein Cell membrane%3B Chaperone%3B Competence%3B Disulfide bond%3B Electron transport%3B Membrane%3B Oxidoreductase%3B Redox-active center%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Required for the stabilization%2C possibly via formation of a disulfide bond%2C of the obligatory competence protein ComGC. Not normally required for production of the secreted lantibiotic sublancin 168%2C although it can partially substitute for BdbB when the latter is absent. It may also be required for the stability of other secreted proteins. Not required for sporulation%3B Belongs to the DsbB family. BdbC subfamily gene gene3068 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03069 S100141_03070 S100141_03070 S100141_03070 2814981 2815676 - Disulfide bond formation protein D Competence%3B Disulfide bond%3B Oxidoreductase%3B Redox-active center%3B Signal%3B Required for the stabilization%2C possibly via formation of a disulfide bond%2C of the obligatory competence protein ComGC. May be required for the stability of secreted proteins with disulfide bonds. Not required for sporulation%3B Belongs to the thioredoxin family. DsbA subfamily%3B Contains 1 thioredoxin domain gene gene3069 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03070 S100141_03071 S100141_03071 S100141_03071 2815802 2817913 - Cadmium-exporting ATPase ATP-binding%3B Cadmium%3B Cadmium resistance%3B Cell membrane%3B Cobalt%3B Cobalt transport%3B Copper%3B Copper transport%3B Hydrolase%3B Ion transport%3B Magnesium%3B Membrane%3B Metal-binding%3B Nucleotide-binding%3B Phosphoprotein%3B Stress response%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Zinc%3B Zinc transport%3B Couples the hydrolysis of ATP with the transport of cadmium%2C zinc and cobalt out of the cell. Does not seem to transport copper%3B Belongs to the cation transport ATPase (P-type) (TC 3. A. 3) family. Type IB subfamily%3B Contains 1 HMA domain%3B KEGG: bli:BL03007 Cd2+/Zn2+-exporting ATPase gene gene3070 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03071 S100141_03072 S100141_03072 S100141_03072 2818166 2819380 + Putative binding protein Periplasm%3B Signal%3B Transport%3B Probably part of an ABC transporter complex. Belongs to the bacterial solute-binding protein 1 family gene gene3071 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03072 S100141_03073 S100141_03073 S100141_03073 2819407 2820300 + Inner membrane ABC transporter permease protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably part of the binding-protein-dependent transport system YcjNOP. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3072 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03073 S100141_03074 S100141_03074 S100141_03074 2820297 2821118 + putative ABC transporter permease protein YurM Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably part of the binding-protein-dependent transport system YurMNO. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3073 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03074 S100141_03075 S100141_03075 yicI yicI 2821140 2823449 + Alpha-D-xyloside xylohydrolase Glycosidase%3B Hydrolase%3B Can catalyze the transfer of alpha-xylosyl residue from alpha-xyloside to xylose%2C glucose%2C mannose%2C fructose%2C maltose%2C isomaltose%2C nigerose%2C kojibiose%2C sucrose and trehalose%3B Belongs to the glycosyl hydrolase 31 family%3B KEGG: scu:SCE1572_13305 alpha-D-xyloside xylohydrolase gene gene3074 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03075 S100141_03076 S100141_03076 bglX bglX 2823465 2826410 + Beta-glucosidase Carbohydrate metabolism%3B Extracellular matrix%3B Glycoprotein%3B Glycosidase%3B Hydrolase%3B Multifunctional enzyme%3B Polysaccharide degradation%3B Secreted%3B Signal%3B Xylan degradation%3B A bifunctional beta-xylosidase/alpha-L-arabinosidase%2C exo-enzyme that acts synergistically with endohydrolases. Releases xylose and arabinose from cell walls. Does not cleave xylan from oat spelts although xylan from oat spelts was degraded to xylose when this enzyme was used in combination with xylanase. Also releases xylose and arabinose from aryl glycosides%2C xylo- oligosaccharides%2C arabinan from sugar beet and arabino- oligosaccharides%2C arabinan from sugar beet and arabinoxylan from wheat%3B Belongs to the glycoside hydrolase 3 family%3B KEGG: bli:BL02680 beta-glucosidase gene gene3075 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03076 S100141_03077 S100141_03077 S100141_03077 2826626 2827378 + Octopine permease ATP-binding protein ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Plasmid%3B Transport%3B Component of the octopine active transport system probably consisting of four subunits: Q%2C M%2C P and T%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene3076 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03077 S100141_03078 S100141_03078 S100141_03078 2827378 2828238 + Manganese transport system membrane protein MntC Cell membrane%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B This protein is probably a component of a manganese permease%2C a binding protein-dependent%2C ATP-driven transport system%3B Belongs to the ABC-3 integral membrane protein family gene gene3077 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03078 S100141_03079 S100141_03079 S100141_03079 2828266 2829195 + Zinc-binding protein AdcA Ion transport%3B Signal%3B Transport%3B Zinc%3B Zinc transport%3B Part of the ATP-driven transport system AdcABC for zinc. Belongs to the bacterial solute-binding protein 9 family gene gene3078 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03079 S100141_03080 S100141_03080 S100141_03080 2829300 2829626 + putative cysteine-rich protein YhjQ gene gene3079 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03080 S100141_03081 S100141_03081 S100141_03081 2829736 2829951 + hypothetical protein gene gene3080 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03081 S100141_03082 S100141_03082 S100141_03082 2829984 2830514 + putative HTH-type transcriptional regulator DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH rpiR-type DNA-binding domain%3B Contains 1 SIS domain gene gene3081 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03082 S100141_03083 S100141_03083 fruK fruK 2830598 2831512 + 1-phosphofructokinase ATP-binding%3B Kinase%3B Lactose metabolism%3B Nucleotide-binding%3B Transferase%3B Belongs to the carbohydrate kinase PfkB family. LacC subfamily%3B KEGG: bli:BL01904 1-phosphofructokinase gene gene3082 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03083 S100141_03084 S100141_03084 S100141_03084 2831526 2832926 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Membrane%3B Phosphoprotein%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport (By similarity)%3B Contains 1 PTS EIIA type-2 domain%3B Contains 1 PTS EIIB type-2 domain%3B Contains 1 PTS EIIC type-2 domain%3B KEGG: bld:BLi03550 PTS system%2C fructose-specific IIB component gene gene3083 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03084 S100141_03085 S100141_03085 S100141_03085 2832933 2833391 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Membrane%3B Phosphoprotein%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport (By similarity)%3B Contains 1 PTS EIIA type-2 domain%3B Contains 1 PTS EIIB type-2 domain%3B Contains 1 PTS EIIC type-2 domain%3B KEGG: bld:BLi03551 PTS system%2C fructose-specific IIA component gene gene3084 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03085 S100141_03086 S100141_03086 S100141_03086 2833417 2834268 + Tagatose-bisphosphate aldolase Galactitol metabolism%3B Lyase%3B Metal-binding%3B Zinc%3B Catalytic subunit of the tagatose-1%2C6-bisphosphate aldolase GatYZ%2C which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1%2C6- bisphosphate (TBP). Requires GatZ subunit for full activity and stability. Is involved in the catabolism of galactitol and D- tagatose%3B Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase GatY subfamily%3B KEGG: bli:BL01900 tagatose 1%2C6-diphosphate aldolase GatY/KbaY gene gene3085 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03086 S100141_03087 S100141_03087 S100141_03087 2834313 2834462 - hypothetical protein gene gene3086 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03087 S100141_03088 S100141_03088 copA copA 2834459 2836894 - Cu(+) exporting ATPase ATP-binding%3B Cell membrane%3B Copper%3B Copper transport%3B Hydrolase%3B Ion transport%3B Magnesium%3B Membrane%3B Metal-binding%3B Nucleotide-binding%3B Phosphoprotein%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in copper export%3B Belongs to the cation transport ATPase (P-type) (TC 3. A. 3) family. Type IB subfamily%3B Contains 2 HMA domains%3B KEGG: bli:BL01899 Cu+-exporting ATPase gene gene3087 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03088 S100141_03089 S100141_03089 S100141_03089 2836931 2837140 - Copper chaperone CopZ Chaperone%3B Copper%3B Cytoplasm%3B Metal-binding%3B Chaperone that serves for the intracellular sequestration and transport of Cu(+). Delivers Cu(+) to the copper-transporting ATPase CopA. Contains 1 HMA domain gene gene3088 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03089 S100141_03090 S100141_03090 S100141_03090 2837235 2837537 - Copper-sensing transcriptional repressor CsoR Copper%3B Cytoplasm%3B DNA-binding%3B Metal-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Copper-sensitive repressor that has a key role in copper homeostasis. Negatively regulates expression of the copZA operon and of ycnJ. In the absence of copper ions%2C binds with high affinity to the copZA promoter and represses the transcription. In the presence of copper ions%2C CsoR binds Cu(1+)%2C which significantly decreases its DNA binding affinity and leads to the transcription of the genes%3B Belongs to the CsoR family gene gene3089 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03090 S100141_03091 S100141_03091 pfpI pfpI 2837661 2838212 - Protein DJ-1 like protein Lyase%3B Oxidation%3B Repeat%3B Stress response%3B Possesses glyoxalase I activity. Catalyzes the conversion of hemimercaptal%2C formed from methylglyoxal and glutathione%2C to S-lactoylglutathione. May be involved in oxidative stress response%3B Belongs to the peptidase C56 family%3B Contains 2 PfpI endopeptidase domains%3B KEGG: bcy:Bcer98_3045 protease I%3B Glycosylases gene gene3090 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03091 S100141_03092 S100141_03092 S100141_03092 2838298 2839059 - putative HTH-type transcriptional regulator YulB DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH deoR-type DNA-binding domain gene gene3091 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03092 S100141_03093 S100141_03093 rhaB rhaB 2839139 2840620 - Rhamnulokinase ATP-binding%3B Cytoplasm%3B Isomerase%3B Kinase%3B Manganese%3B Metal-binding%3B Multifunctional enzyme%3B Nucleotide-binding%3B Rhamnose metabolism%3B Transferase%3B In the N-terminal sectio%3B belongs to the rhamnulokinase family%3B In the C-terminal sectio%3B belongs to the rhamnose isomerase family%3B KEGG: bli:BL00812 rhamnulokinase gene gene3092 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03093 S100141_03094 S100141_03094 rhaA rhaA 2840617 2841840 - putative sugar isomerase Isomerase%3B Manganese%3B Metal-binding%3B Belongs to the rhamnose isomerase family%3B KEGG: bli:BL00813 L-rhamnose isomerase / sugar isomerase gene gene3093 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03094 S100141_03095 S100141_03095 S100141_03095 2841830 2842219 - hypothetical protein gene gene3094 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03095 S100141_03096 S100141_03096 S100141_03096 2842274 2844343 - putative oxidoreductase YuxG Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bsu:BSU31220 null%3B Oxidoreductases gene gene3095 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03096 S100141_03097 S100141_03097 S100141_03097 2844705 2845823 + putative MFS-type transporter YfhI Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene3096 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03097 S100141_03098 S100141_03098 S100141_03098 2845820 2845909 + hypothetical protein gene gene3097 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03098 S100141_03099 S100141_03099 S100141_03099 2845927 2847153 - putative MFS-type transporter YvmA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily. TCR/Tet family gene gene3098 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03099 S100141_03100 S100141_03100 yvmC yvmC 2847689 2848438 + Cyclo(L-leucyl-L-leucyl) synthase Transferase%3B Involved in the biosynthesis of pulcherrimin%2C a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues%2C such as L- phenylalanine%2C L-leucine and methionine%2C into cyclodipeptides%3B Belongs to the CDPS family%3B KEGG: bli:BL00817 cyclo(L-leucyl-L-leucyl) synthase gene gene3099 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03100 S100141_03101 S100141_03101 S100141_03101 2848435 2849655 + Pulcherriminic acid synthase Heme%3B Iron%3B Metal-binding%3B Monooxygenase%3B Oxidoreductase%3B Involved in the biosynthesis of pulcherrimin%2C a red extracellular pigment. Catalyzes the oxidation of cyclo(L-Leu-L- Leu) (cLL) to yield pulcherriminic acid which forms pulcherrimin via a nonenzymic reaction with Fe(3+). Substrates with small alkyl groups (cAA%2C cLG%2C cLP) exhibit weaker binding to CYP134A1%2C but substrates with larger hydrophobic side chains bind in a similar regime to cLL%3B Belongs to the cytochrome P450 family%3B KEGG: bli:BL00818 pulcherriminic acid synthase gene gene3100 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03101 S100141_03102 S100141_03102 S100141_03102 2849652 2850107 - hypothetical protein gene gene3101 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03102 S100141_03103 S100141_03103 S100141_03103 2850124 2850597 - putative HTH-type transcriptional regulator YvnA Cytoplasm%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH marR-type DNA-binding domain gene gene3102 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03103 S100141_03104 S100141_03104 amiE amiE 2850720 2851157 - Amidase Chloroplast%3B Membrane%3B Plastid%3B Plastid outer membrane%3B Protein transport%3B Repeat%3B TPR repeat%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Chaperone receptor mediating Hsp90-dependent protein targeting to chloroplasts. Bi-functional preprotein receptor acting on both sides of the membrane. Not essential for an efficient import of pre-proteins into plastids%3B Contains 3 TPR repeats%3B KEGG: blh:BaLi_c36320 amidase gene gene3103 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03104 S100141_03105 S100141_03105 S100141_03105 2851232 2851897 - Amidase Acetylation%3B Auxin biosynthesis%3B Cytoplasm%3B Hydrolase%3B Amidase involved in auxin biosynthesis. Converts indole- 3-acetamide into indole-3-acetic acid. Can also use L-asparagine%2C oleamide and 1-naphtalene-acetamide as substrates%2C but not indole- 3-acetonitrile or indole-3-acetyl-L-aspartic acid%3B Belongs to the amidase family%3B KEGG: blh:BaLi_c36320 amidase gene gene3104 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03105 S100141_03106 S100141_03106 iolW iolW 2852087 2853136 + Scyllo-inositol 2-dehydrogenase (NADP(+)) NADP%3B Oxidoreductase%3B Catalyzes the NADP(+)-dependent oxidation of scyllo- inositol to 2%2C4%2C6/3%2C5-pentahydroxycyclohexanone (scyllo-inosose)%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: bli:BL00819 scyllo-inositol 2-dehydrogenase (NADP+) gene gene3105 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03106 S100141_03107 S100141_03107 S100141_03107 2853168 2853803 - FMN-dependent NADH-azoreductase Flavoprotein%3B FMN%3B NAD%3B Oxidoreductase%3B Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH%2C but not NADPH%2C as an electron donor for its activity%3B Belongs to the azoreductase type 1 family%3B KEGG: bli:BL00833 FMN-dependent NADH-azoreductase%3B Acting on other nitrogenous compounds as donors gene gene3106 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03107 S100141_03108 S100141_03108 S100141_03108 2853766 2853945 - hypothetical protein gene gene3107 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03108 S100141_03109 S100141_03109 S100141_03109 2854104 2855072 - UPF0176 protein Belongs to the UPF0176 family%3B Contains 1 rhodanese domain gene gene3108 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03109 S100141_03110 S100141_03110 S100141_03110 2855268 2855486 - Sigma-O factor regulatory protein RsoA Activator%3B Transcription%3B Transcription regulation%3B Together with RNA polymerase sigma factor SigO%2C positively regulates the expression of at least three operons%2C including oxdC-yvrL%2C sigO-rsoA and yvrJ. Required for the acid stress-dependent induction of the oxalate decarboxylase oxdC gene gene3109 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03110 S100141_03111 S100141_03111 S100141_03111 2855461 2856042 - RNA polymerase sigma factor SigO DNA-binding%3B Sigma factor%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Together with its coactivator RsoA%2C positively regulates the expression of at least three operons%2C including oxdC-yvrL%2C sigO-rsoA and yvrJ. Required for the acid stress- dependent induction of the oxalate decarboxylase oxdC%3B Belongs to the sigma-70 factor family gene gene3110 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03111 S100141_03112 S100141_03112 S100141_03112 2856199 2856348 + uncharacterized protein gene gene3111 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03112 S100141_03113 S100141_03113 S100141_03113 2856442 2857596 + Oxalate decarboxylase Cytoplasm%3B Decarboxylase%3B Lyase%3B Manganese%3B Metal-binding%3B Converts oxalate to formate and CO(2) in an O(2)- dependent reaction. Can also catalyze minor side reactions: oxalate oxidation to produce H(2)O(2)%2C and oxalate-dependent%2C H(2)O(2)-independent dye oxidations%3B To B. subtilis OxdD%3B KEGG: bli:BL00821 oxalate decarboxylase gene gene3112 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03113 S100141_03114 S100141_03114 S100141_03114 2857669 2858067 + Membrane-bound negative regulator YvrL Cell membrane%3B Membrane%3B Repressor%3B Transmembrane%3B Transmembrane helix%3B Negatively regulates RNA polymerase sigma factor SigO- dependent transcription. Prevents the expression or secretion of OxdC under nonstress conditions. May act as an anti-sigma factor gene gene3113 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03114 S100141_03115 S100141_03115 S100141_03115 2858164 2858649 + hypothetical protein gene gene3114 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03115 S100141_03116 S100141_03116 S100141_03116 2858802 2859029 + hypothetical protein gene gene3115 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03116 S100141_03117 S100141_03117 S100141_03117 2859154 2859312 - hypothetical protein gene gene3116 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03117 S100141_03118 S100141_03118 S100141_03118 2859512 2860054 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3117 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03118 S100141_03119 S100141_03119 S100141_03119 2860227 2860607 + hypothetical protein gene gene3118 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03119 S100141_03120 S100141_03120 S100141_03120 2860882 2862600 + Putative ribonuclease YwqJ Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Probable toxic component of a toxin-antitoxin (TA) module. The C-terminus may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YwqK%2C but not by antitoxins specific to other toxins with the LXG domain (By similarity)%3B Contains 1 LXG domain gene gene3119 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03120 S100141_03121 S100141_03121 S100141_03121 2862606 2862890 + hypothetical protein gene gene3120 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03121 S100141_03122 S100141_03122 S100141_03122 2862921 2863130 - N-acetylmuramoyl-L-alanine amidase Cell wall biogenesis/degradation%3B Hydrolase%3B Repeat%3B Secreted%3B Signal%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B KEGG: bay:RBAM_012470 N-acetylmuramoyl-L-alanine amidase gene gene3121 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03122 S100141_03123 S100141_03123 S100141_03123 2863871 2864344 - SsrA-binding protein Cytoplasm%3B RNA-binding%3B Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA)%2C required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape%2C replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gen%3B the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide'%2C a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA%2C entering the A-site of stalled ribosomes%2C displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRN%3B the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation%2C which seems to be the essential function of trans- translation%3B Belongs to the SmpB family gene gene3122 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03123 S100141_03124 S100141_03124 vacB vacB 2864456 2866759 - Ribonuclease Cytoplasm%3B Exonuclease%3B Hydrolase%3B Nuclease%3B RNA-binding%3B 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs%3B Belongs to the RNR ribonuclease family. RNase R subfamily%3B Contains 1 S1 motif domain%3B KEGG: bli:BL03482 ribonuclease R%3B Acting on ester bonds gene gene3123 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03124 S100141_03125 S100141_03125 yvaK yvaK 2866773 2867519 - Carboxylesterase Hydrolase%3B Serine esterase%3B Involved in the detoxification of xenobiotics. Shows maximal activity with C6 substrates%2C with gradually decreasing activity from C8 to C12 substrates. No activity for higher chain length substrates acids rather than long-chain ones (By similarity)%3B Belongs to the lipase/esterase LIP3/BchO family%3B KEGG: bli:BL03481 carboxylesterase gene gene3124 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03125 S100141_03126 S100141_03126 S100141_03126 2867660 2867890 - putative protein-export membrane protein SecG Cell membrane%3B Membrane%3B Protein transport%3B Translocation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in protein export. Participates in an early event of protein translocation (By similarity)%3B Belongs to the SecG family gene gene3125 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03126 S100141_03127 S100141_03127 S100141_03127 2868061 2868345 - Transition state regulatory protein AbrB Activator%3B DNA-binding%3B Repressor%3B Sporulation%3B Transcription%3B Transcription regulation%3B Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites%2C it may be the sole repressor of tycA transcription%3B Contains 1 SpoVT-AbrB domain%3B To B. subtilis Abh and SpoVT gene gene3126 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03127 S100141_03128 S100141_03128 S100141_03128 2868374 2868691 - putative HTH-type transcriptional regulator YvzC Cytoplasm%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene3127 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03128 S100141_03129 S100141_03129 S100141_03129 2868760 2869161 + HTH-type transcriptional repressor RghR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Represses the expression of yvaM and both rapG and rapH. Binds directly to the promoter regions of yvaM%2C rapG and rapH%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene3128 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03129 S100141_03130 S100141_03130 S100141_03130 2869331 2869729 + Repressor LexA DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH cro/C1-type DNA-binding domain%3B KEGG: aac:Aaci_2954 repressor LexA gene gene3129 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03130 S100141_03131 S100141_03131 S100141_03131 2869777 2870454 - Choline transport system permease protein OpuBD Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in a high affinity multicomponent binding- protein-dependent transport system for cholin%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3130 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03131 S100141_03132 S100141_03132 S100141_03132 2870471 2871388 - Glycine betaine/carnitine/choline-binding protein OpuCC Amino-acid transport%3B Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B Member of a high affinity multicomponent binding- protein-dependent transport system for glycine betaine%2C carnitine%2C and choline%3B Belongs to the OsmX family gene gene3131 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03132 S100141_03133 S100141_03133 S100141_03133 2871402 2872055 - Glycine betaine/carnitine/choline transport system permease protein OpuCB Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine%2C carnitine and cholin%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3132 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03133 S100141_03134 S100141_03134 S100141_03134 2872077 2873216 - Energy-coupling factor transporter ATP-binding protein EcfA ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the ABC transporter superfamily. Energy- coupling factor EcfA family%3B Contains 1 ABC transporter domain gene gene3133 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03134 S100141_03135 S100141_03135 S100141_03135 2873474 2874013 + HTH-type transcriptional repressor OpcR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Negatively regulates the transcription of the opuC operon. In the absence of GbsR%2C is also a negative regulator of the opuB operon. Binds to an inverted repeat in the promoter region of the operons%3B Belongs to the GbsR family gene gene3134 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03135 S100141_03136 S100141_03136 S100141_03136 2874060 2874692 - UPF0056 membrane protein YvbG Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0056 (MarC) family gene gene3135 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03136 S100141_03137 S100141_03137 S100141_03137 2874855 2875634 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3136 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03137 S100141_03138 S100141_03138 S100141_03138 2875678 2876805 - putative membrane protein YvbJ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B overlaps another CDS with the same product name gene gene3137 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03138 S100141_03139 S100141_03139 S100141_03139 2876780 2877445 - putative membrane protein YvbJ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B overlaps another CDS with the same product name gene gene3138 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03139 S100141_03140 S100141_03140 S100141_03140 2877574 2878521 - Fe(3+)-citrate-binding protein YfmC Cell membrane%3B Ion transport%3B Iron%3B Iron transport%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B Part of the ABC transporter complex YfmCDEF involved in citrate-dependent Fe(3+) import. Binds citrate-dependent Fe(3+) and delivers it to the surface of YfmDE (Probable)%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene3139 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03140 S100141_03141 S100141_03141 S100141_03141 2878809 2879201 + hypothetical protein gene gene3140 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03141 S100141_03142 S100141_03142 S100141_03142 2879804 2880436 - putative protease YoaZ Hydrolase%3B Protease%3B Belongs to the peptidase C56 family%3B Contains 1 PfpI endopeptidase domain gene gene3141 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03142 S100141_03143 S100141_03143 S100141_03143 2880572 2881864 - Phosphopyruvate hydratase Cytoplasm%3B Glycolysis%3B Lyase%3B Magnesium%3B Metal-binding%3B Secreted%3B Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis%3B Belongs to the enolase family%3B KEGG: bsu:BSU33900 enolase gene gene3142 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03143 S100141_03144 S100141_03144 gpmI gpmI 2881887 2883422 - Phosphoglycerate mutase (2%2C3-diphosphoglycerate-independent) Glycolysis%3B Isomerase%3B Manganese%3B Metal-binding%3B Phosphoprotein%3B Sporulation%3B Essential for rapid growth and for sporulation. Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate%3B Belongs to the BPG-independent phosphoglycerate mutase family%3B KEGG: bli:BL03467 2%2C3-bisphosphoglycerate-independent phosphoglycerate mutase gene gene3143 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03144 S100141_03145 S100141_03145 tpiA tpiA 2883415 2884176 - Triose-phosphate isomerase Cytoplasm%3B Gluconeogenesis%3B Glycolysis%3B Isomerase%3B Pentose shunt%3B Belongs to the triosephosphate isomerase family%3B KEGG: mej:Q7A_2894 triosephosphate isomerase (TIM) gene gene3144 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03145 S100141_03146 S100141_03146 S100141_03146 2884207 2885391 - Phosphoglycerate kinase ATP-binding%3B Cytoplasm%3B Glycolysis%3B Kinase%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Belongs to the phosphoglycerate kinase family%3B KEGG: sat:SYN_01396 phosphoglycerate kinase gene gene3145 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03146 S100141_03147 S100141_03147 S100141_03147 2885565 2886572 - Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) Cytoplasm%3B Glycolysis%3B NAD%3B Nucleotide-binding%3B Oxidoreductase%3B Involved in the glycolysis. Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1%2C3- bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue%2C and this hemiacetal intermediate is then oxidized to a thioester%2C with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD%2C and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG%3B Belongs to the glyceraldehyde-3-phosphate dehydrogenase family%3B KEGG: eco:b1779 glyceraldehyde 3-phosphate dehydrogenase gene gene3146 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03147 S100141_03148 S100141_03148 S100141_03148 2886606 2887646 - Central glycolytic protein regulator DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B In the absence of glucose%2C represses the transcription of the gapA operon%2C which encodes five key glycolytic enzymes. Binds specifically to the cggR-gapA promoter region and blocks the progression of the RNA polymerase%2C leading to the arrest of the transcription%3B Belongs to the SorC transcriptional regulatory family gene gene3147 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03148 S100141_03149 S100141_03149 S100141_03149 2888048 2889055 - uncharacterized protein To bacterial alkanal monooxygenase alpha and beta chains gene gene3148 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03149 S100141_03150 S100141_03150 S100141_03150 2889195 2890550 - Putative histidine permease Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene3149 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03150 S100141_03151 S100141_03151 S100141_03151 2891193 2891666 + hypothetical protein gene gene3150 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03151 S100141_03152 S100141_03152 S100141_03152 2891843 2892769 - Galactose/methyl galactoside import ATP-binding protein MglA ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Repeat%3B Sugar transport%3B Transport%3B Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3. A. 1. 2. 3) family%3B Contains 2 ABC transporter domains gene gene3151 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03152 S100141_03153 S100141_03153 S100141_03153 2892769 2893458 - hypothetical protein gene gene3152 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03153 S100141_03154 S100141_03154 S100141_03154 2893792 2894514 - Lactate utilization protein Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source%3B Belongs to the LutC/YkgG family%3B overlaps another CDS with the same product name gene gene3153 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03154 S100141_03155 S100141_03155 S100141_03155 2894511 2895944 - Lactate utilization protein 4Fe-4S%3B Electron transport%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Repeat%3B Transport%3B Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate%3B Belongs to the LutB/YkgF family%3B Contains 2 4Fe-4S ferredoxin-type domains%3B overlaps another CDS with the same product name gene gene3154 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03155 S100141_03156 S100141_03156 S100141_03156 2895988 2896773 - Lactate utilization protein A Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source%3B Belongs to the LutA/YkgE family gene gene3155 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03156 S100141_03157 S100141_03157 S100141_03157 2896847 2897587 - Exu regulon transcriptional regulator DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the ExuT%2C UxaCA and UxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers. Contains 1 HTH gntR-type DNA-binding domain gene gene3156 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03157 S100141_03158 S100141_03158 S100141_03158 2897795 2899486 + L-lactate permease Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Is the principal permease for the uptake of L-lactate in B. subtilis%3B Belongs to the lactate permease family gene gene3157 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03158 S100141_03159 S100141_03159 S100141_03159 2899520 2900833 - RNA polymerase sigma-54 factor DNA-binding%3B DNA-directed RNA polymerase%3B Nucleotidyltransferase%3B Sigma factor%3B Transcription%3B Transcription regulation%3B Transferase%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of the levanase operon. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for receipt of the melting signal from the remotely bound activator protein LevR for the expression of the levanase operon. Belongs to the sigma-54 factor family gene gene3158 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03159 S100141_03160 S100141_03160 S100141_03160 2900904 2901119 + uncharacterized protein gene gene3159 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03160 S100141_03161 S100141_03161 epsO epsO 2901135 2902112 - Putative pyruvyl transferase EpsO Exopolysaccharide synthesis%3B Transferase%3B May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Belongs to the polysaccharide pyruvyl transferase family%3B KEGG: bli:BL03453 pyruvyl transferase EpsO%3B Transferases gene gene3160 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03161 S100141_03162 S100141_03162 epsN epsN 2902123 2903268 - Putative pyridoxal phosphate-dependent aminotransferase EpsN Aminotransferase%3B Exopolysaccharide synthesis%3B Pyridoxal phosphate%3B Transferase%3B May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Belongs to the DegT/DnrJ/EryC1 family%3B KEGG: bli:BL03452 pyridoxal phosphate-dependent aminotransferase EpsN%3B Transaminases gene gene3161 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03162 S100141_03163 S100141_03163 epsM epsM 2903292 2903918 - Putative acetyltransferase EpsM Acyltransferase%3B Exopolysaccharide synthesis%3B Repeat%3B Transferase%3B May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Belongs to the transferase hexapeptide repeat family%3B KEGG: bli:BL03451 acetyltransferase EpsM%3B Transferring groups other than amino-acyl groups gene gene3162 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03163 S100141_03164 S100141_03164 S100141_03164 2903918 2904520 - Undecaprenyl-phosphate glucose phosphotransferase Exopolysaccharide synthesis%3B Glycosyltransferase%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Involved in the biosynthesis of the exopolysaccharide acetan%2C a water-soluble polysaccharide involved in production of bacterial cellulose (BC)%3B Belongs to the bacterial sugar transferase family gene gene3163 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03164 S100141_03165 S100141_03165 S100141_03165 2904541 2906097 - putative membrane protein EpsK Cell membrane%3B Exopolysaccharide synthesis%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3164 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03165 S100141_03166 S100141_03166 epsJ epsJ 2906094 2907113 - Chondroitin synthase Glycosyltransferase%3B Repeat%3B Transferase%3B Catalyzes the polymerization of chondroitin%2C a polysaccharide composed of a repeating disaccharide of N- acetylgalactosamine (GalNAc) and glucuronic acid (GlcUA) units. Each unit has the composition in beta-(1->4)-GlcUA-beta-(1->3)- GalNAc. Belongs to the glycosyltransferase 2 family. CS/HAS subfamily%3B KEGG: bli:BL03447 glycosyltransferase EpsJ%3B Glycosyltransferases gene gene3165 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03166 S100141_03167 S100141_03167 epsI epsI 2907110 2908189 - Putative pyruvyl transferase EpsI Exopolysaccharide synthesis%3B Transferase%3B May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Belongs to the polysaccharide pyruvyl transferase family%3B KEGG: bli:BL03446 pyruvyl transferase EpsI%3B Transferases gene gene3166 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03167 S100141_03168 S100141_03168 epsH epsH 2908201 2909232 - Putative glycosyltransferase EpsH Exopolysaccharide synthesis%3B Glycosyltransferase%3B Transferase%3B May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance%3B Belongs to the glycosyltransferase 2 family%3B KEGG: bli:BL03445 glycosyltransferase EpsH%3B Glycosyltransferases gene gene3167 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03168 S100141_03169 S100141_03169 S100141_03169 2909292 2910395 - Transmembrane protein EpsG Cell membrane%3B Exopolysaccharide synthesis%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3168 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03169 S100141_03170 S100141_03170 epsF epsF 2910400 2911560 - Putative glycosyltransferase EpsF Exopolysaccharide synthesis%3B Glycosyltransferase%3B Transferase%3B May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance. Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: bli:BL03443 glycosyltransferase EpsF%3B Glycosyltransferases gene gene3169 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03170 S100141_03171 S100141_03171 epsE epsE 2911553 2912395 - Putative glycosyltransferase EpsE Exopolysaccharide synthesis%3B Glycosyltransferase%3B Transferase%3B May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance. Belongs to the glycosyltransferase 2 family%3B KEGG: bli:BL03442 glycosyltransferase EpsE%3B Glycosyltransferases gene gene3170 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03171 S100141_03172 S100141_03172 epsD epsD 2912392 2913540 - Putative glycosyltransferase EpsD Exopolysaccharide synthesis%3B Glycosyltransferase%3B Transferase%3B May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance. Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: bli:BL03441 glycosyltransferase EpsD%3B Glycosyltransferases gene gene3171 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03172 S100141_03173 S100141_03173 S100141_03173 2913551 2915368 - putative polysaccharide biosynthesis protein EpsC Cell membrane%3B Exopolysaccharide synthesis%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Involved in biofilm formation%3B Belongs to the polysaccharide synthase family gene gene3172 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03173 S100141_03174 S100141_03174 epsB epsB 2915629 2916321 - Non-specific protein-tyrosine kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Tyrosine-protein kinase%3B Belongs to the CpsD/CapB family%3B KEGG: bli:BL03438 protein-tyrosine kinase gene gene3173 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03174 S100141_03175 S100141_03175 S100141_03175 2916311 2917063 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the CpsC/CapA family gene gene3174 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03175 S100141_03176 S100141_03176 S100141_03176 2917299 2917757 + HTH-type transcriptional regulator SlrR DNA-binding%3B Transcription%3B Transcription regulation%3B Represses sigma(D)-dependent flagellar genes and activate the eps and yqxM operons. Repressor activity is regulated by SlrA. Controls the initiation of biofilm formation%3B Contains 1 HTH cro/C1-type DNA-binding domain%3B Contains 1 Sin domain gene gene3175 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03176 S100141_03177 S100141_03177 S100141_03177 2918167 2918691 + General stress protein Oxidoreductase%3B Stress response%3B Belongs to the NAD(P)H dehydrogenase (quinone) family gene gene3176 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03177 S100141_03178 S100141_03178 S100141_03178 2918728 2920011 - putative glucarate transporter Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Uptake of D-glucarate. Belongs to the major facilitator superfamily. Phthalate permease family gene gene3177 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03178 S100141_03179 S100141_03179 S100141_03179 2920081 2921031 - Phosphoglycerate dehydrogenase Amino-acid biosynthesis%3B NAD%3B Oxidoreductase%3B Serine biosynthesis%3B Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family%3B Contains 1 ACT domain%3B KEGG: kpu:KP1_2666 D-3-phosphoglycerate dehydrogenase gene gene3178 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03179 S100141_03180 S100141_03180 S100141_03180 2921059 2922057 - 4-hydroxythreonine-4-phosphate dehydrogenase Cytoplasm%3B Metal-binding%3B NAD%3B NADP%3B Oxidoreductase%3B Pyridoxine biosynthesis%3B Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)%3B Belongs to the PdxA family%3B KEGG: bli:BL03434 4-hydroxythreonine-4-phosphate dehydrogenase gene gene3179 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03180 S100141_03181 S100141_03181 S100141_03181 2922061 2923332 - uncharacterized protein To E. coli YgbK gene gene3180 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03181 S100141_03182 S100141_03182 adhE adhE 2923346 2924512 - Acetaldehyde dehydrogenase (acetylating) Cytoplasm%3B Magnesium%3B Methanol utilization%3B NAD%3B Oxidoreductase%3B Zinc%3B Catalyzes the oxidation of methanol to yield formaldehyde. It possesses a NADH-dependent formaldehyde reductase activity and can not use NADP%3B Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: hor:Hore_02110 acetaldehyde dehydrogenase / alcohol dehydrogenase gene gene3181 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03182 S100141_03183 S100141_03183 S100141_03183 2924526 2925413 - 4-hydroxy-tetrahydrodipicolinate synthase Amino-acid biosynthesis%3B Cytoplasm%3B Diaminopimelate biosynthesis%3B Lyase%3B Lysine biosynthesis%3B Schiff base%3B Catalyzes the condensation of (S)-aspartate-beta- semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)%3B Belongs to the DapA family%3B KEGG: bli:BL03431 4-hydroxy-tetrahydrodipicolinate synthase gene gene3182 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03183 S100141_03184 S100141_03184 S100141_03184 2925557 2927275 - Propionate catabolism operon regulatory protein ATP-binding%3B DNA-binding%3B Nucleotide-binding%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Involved in the transcriptional regulation of the propionate catabolism operon. Contains 1 sigma-54 factor interaction domain gene gene3183 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03184 S100141_03185 S100141_03185 S100141_03185 2927247 2927699 - putative HTH-type transcriptional regulator DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH hxlR-type DNA-binding domain gene gene3184 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03185 S100141_03186 S100141_03186 fadH fadH 2927871 2928965 + 2%2C4-dienoyl-CoA reductase (NADPH) FAD%3B Flavoprotein%3B NAD%3B Oxidoreductase%3B Belongs to the NADH:flavin oxidoreductase/NADH oxidase family%3B KEGG: bur:Bcep18194_C7286 2%2C4-dienoyl-CoA reductase (NADPH2) gene gene3185 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03186 S100141_03187 S100141_03187 sacB sacB 2929315 2930763 + Levansucrase Glycosyltransferase%3B Secreted%3B Signal%3B Transferase%3B Belongs to the glycosyl hydrolase 68 family%3B KEGG: blh:BaLi_c37120 levansucrase gene gene3186 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03187 S100141_03188 S100141_03188 levB levB 2930840 2932387 + 2%2C6-beta-fructan 6-levanbiohydrolase Carbohydrate metabolism%3B Cell membrane%3B Glycosidase%3B Hydrolase%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the degradation of levan mainly into levanbiose (difructose). Is not active on sucrose%3B Belongs to the glycosyl hydrolase 32 family%3B KEGG: bli:BL03606 levanbiose-producing levanase gene gene3187 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03188 S100141_03189 S100141_03189 S100141_03189 2932513 2932588 - tRNA-Arg tRNA gene3188 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03189 S100141_03190 S100141_03190 S100141_03190 2932685 2933002 - hypothetical protein gene gene3189 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03190 S100141_03191 S100141_03191 S100141_03191 2933243 2933839 + Endopeptidase Clp Cytoplasm%3B Hydrolase%3B Protease%3B Serine protease%3B Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins%3B Belongs to the peptidase S14 family%3B KEGG: eco:b0437 ATP-dependent Clp protease%2C protease subunit gene gene3190 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03191 S100141_03192 S100141_03192 S100141_03192 2933919 2934494 - putative cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG6 Cytokinin biosynthesis%3B Hydrolase%3B Cytokinin-activating enzyme working in the direct activation pathway. Phosphoribohydrolase that converts inactive cytokinin nucleotides to the biologically active free-base forms (By similarity)%3B Belongs to the LOG family gene gene3191 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03192 S100141_03193 S100141_03193 S100141_03193 2934606 2934941 + uncharacterized protein overlaps another CDS with the same product name gene gene3192 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03193 S100141_03194 S100141_03194 S100141_03194 2934913 2935905 + uncharacterized protein Contains 1 HD domain%3B overlaps another CDS with the same product name gene gene3193 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03194 S100141_03195 S100141_03195 S100141_03195 2935952 2937571 - Putative sulfate transporter YvdB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the SLC26A/SulP transporter (TC 2. A. 53) family%3B Contains 1 STAS domain gene gene3194 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03195 S100141_03196 S100141_03196 S100141_03196 2937593 2938183 - Carbonate dehydratase Lyase%3B Metal-binding%3B Zinc%3B Reversible hydration of carbon dioxide%3B Belongs to the beta-class carbonic anhydrase family%3B KEGG: bli:BL03424 carbonic anhydrase gene gene3195 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03196 S100141_03197 S100141_03197 S100141_03197 2938580 2939551 + Gluconate 2-dehydrogenase Gluconate utilization%3B NADP%3B Oxidoreductase%3B Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family%3B KEGG: bsu:BSU34680 gluconate 2-dehydrogenase gene gene3196 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03197 S100141_03198 S100141_03198 S100141_03198 2939562 2940161 - uncharacterized protein Flavoprotein%3B Belongs to the flavoredoxin family gene gene3197 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03198 S100141_03199 S100141_03199 S100141_03199 2940250 2940945 + putative HTH-type transcriptional regulator YdfF DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH arsR-type DNA-binding domain gene gene3198 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03199 S100141_03200 S100141_03200 S100141_03200 2941203 2941658 + Ribonuclease Endonuclease%3B Hydrolase%3B Nuclease%3B Secreted%3B Signal%3B Hydrolyzes phosphodiester bonds in RNA%2C poly- and oligoribonucleotides resulting in 3'-nucleoside monophosphates via 2'%2C3'-cyclophosphate intermediates. Belongs to the ribonuclease N1/T1 family gene gene3199 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03200 S100141_03201 S100141_03201 S100141_03201 2941663 2941938 + Barstar Cytoplasm%3B Inhibitor of the ribonuclease barnase. Forms a one-to- one non-covalent complex. Belongs to the barstar family gene gene3200 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03201 S100141_03202 S100141_03202 nhoA nhoA 2942006 2942764 - N-hydroxyarylamine O-acetyltransferase Acyltransferase%3B Transferase%3B Belongs to the arylamine N-acetyltransferase family%3B KEGG: blh:BaLi_c37260 N-hydroxyarylamine O-acetyltransferase gene gene3201 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03202 S100141_03203 S100141_03203 S100141_03203 2942807 2943076 - HPr-like protein Crh Phosphoprotein%3B Along with seryl-phosphorylated HPr%2C phosphorylated Crh is implicated in carbon catabolite repression (CCR) of levanase%2C inositol dehydrogenase%2C and beta-xylosidase. Exerts its effect on CCR by interacting with CcpA%3B Belongs to the HPr family%3B Contains 1 HPr domain gene gene3202 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03203 S100141_03204 S100141_03204 S100141_03204 2943094 2944044 - Putative sporulation transcription regulator WhiA DNA-binding%3B Transcription%3B Transcription regulation%3B May be required for sporulation%3B Belongs to the WhiA transcriptional regulatory family gene gene3203 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03204 S100141_03205 S100141_03205 S100141_03205 2944073 2945068 - Gluconeoproteinis factor Cytoplasm%3B Required for morphogenesis under gluconeogenic growth conditions. Required%2C in gluconeogenic growth conditions%2C for the correct localization of PBP1 and hence for displaying a normal rod shape%3B Belongs to the gluconeogenesis factor family gene gene3204 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03205 S100141_03206 S100141_03206 S100141_03206 2945028 2945915 - Nucleotide-binding protein ATP-binding%3B GTP-binding%3B Nucleotide-binding%3B Displays ATPase and GTPase activities%3B Belongs to the RapZ-like family gene gene3205 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03206 S100141_03207 S100141_03207 S100141_03207 2945937 2946401 - 8-oxo-dGTP diphosphatase Hydrolase%3B Magnesium%3B Metal-binding%3B Belongs to the Nudix hydrolase family%3B Contains 1 nudix hydrolase domain%3B KEGG: bsu:BSU34780 8-oxo-dGTP diphosphatase gene gene3206 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03207 S100141_03208 S100141_03208 S100141_03208 2946822 2947772 - Thioredoxin-disulfide reductase Cytoplasm%3B Disulfide bond%3B FAD%3B Flavoprotein%3B NADP%3B Oxidoreductase%3B Redox-active center%3B Stress response%3B Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: rsl:RPSI07_mp0554 thioredoxin reductase (NADPH) gene gene3207 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03208 S100141_03209 S100141_03209 S100141_03209 2947939 2949399 - TPR repeat-containing protein YvcD Repeat%3B TPR repeat%3B Contains 3 TPR repeats gene gene3208 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03209 S100141_03210 S100141_03210 S100141_03210 2949694 2950173 + putative N-acetyltransferase YbbJ Acyltransferase%3B Transferase%3B Contains 1 N-acetyltransferase domain gene gene3209 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03210 S100141_03211 S100141_03211 S100141_03211 2950232 2950864 - Phosphoribosyl-ATP diphosphatase Amino-acid biosynthesis%3B Cytoplasm%3B Histidine biosynthesis%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Zinc%3B Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP%3B Belongs to the PRA-CH family%3B KEGG: bli:BL03413 phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase gene gene3210 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03211 S100141_03212 S100141_03212 hisF hisF 2950861 2951619 - Imidazole glycerol phosphate synthase subunit HisF Amino-acid biosynthesis%3B Cytoplasm%3B Histidine biosynthesis%3B Lyase%3B IGPS catalyzes the conversion of PRFAR and glutamine to IGP%2C AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit%3B Belongs to the HisA/HisF family%3B KEGG: xfa:XF2214 cyclase%3B Oxo-acid-lyases gene gene3211 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03212 S100141_03213 S100141_03213 hisA hisA 2951616 2952353 - 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamideisomerase Amino-acid biosynthesis%3B Cytoplasm%3B Histidine biosynthesis%3B Isomerase%3B Belongs to the HisA/HisF family%3B KEGG: bli:BL03411 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase gene gene3212 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03213 S100141_03214 S100141_03214 hisH hisH 2952350 2952988 - Imidazole glycerol phosphate synthase subunit HisH Amino-acid biosynthesis%3B Cytoplasm%3B Glutamine amidotransferase%3B Histidine biosynthesis%3B Transferase%3B IGPS catalyzes the conversion of PRFAR and glutamine to IGP%2C AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: cff:CFF8240_1352 glutamine amidotransferase%3B Pentosyltransferases gene gene3213 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03214 S100141_03215 S100141_03215 hisB hisB 2952989 2953573 - Imidazoleglycerol-phosphate dehydratase Amino-acid biosynthesis%3B Cytoplasm%3B Histidine biosynthesis%3B Lyase%3B Belongs to the imidazoleglycerol-phosphate dehydratase family%3B KEGG: hba:Hbal_3133 imidazoleglycerol-phosphate dehydratase gene gene3214 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03215 S100141_03216 S100141_03216 hisD hisD 2953573 2954853 - Histidinol dehydrogenase Amino-acid biosynthesis%3B Histidine biosynthesis%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Zinc%3B Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine%3B Belongs to the histidinol dehydrogenase family%3B KEGG: bsu:BSU34910 histidinol dehydrogenase gene gene3215 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03216 S100141_03217 S100141_03217 hisG hisG 2954850 2955491 - ATP phosphoribosyltransferase Amino-acid biosynthesis%3B ATP-binding%3B Cytoplasm%3B Glycosyltransferase%3B Histidine biosynthesis%3B Nucleotide-binding%3B Transferase%3B Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity%3B Belongs to the ATP phosphoribosyltransferase family. Short subfamily%3B KEGG: csa:Csal_2213 ATP phosphoribosyltransferase gene gene3216 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03217 S100141_03218 S100141_03218 S100141_03218 2955484 2956659 - ATP phosphoribosyltransferase regulatory subunit Amino-acid biosynthesis%3B Cytoplasm%3B Histidine biosynthesis%3B Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine%3B Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily gene gene3217 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03218 S100141_03219 S100141_03219 S100141_03219 2956895 2957629 + uncharacterized protein Signal. gene gene3218 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03219 S100141_03220 S100141_03220 pelC pelC 2957913 2958578 + Pectate lyase Calcium%3B Lyase%3B Metal-binding%3B Secreted%3B Signal%3B Catalyzes the depolymerization of both polygalacturonate and pectins of methyl esterification degree from 22 to 89%25%2C with an endo mode of action. In contrast to the majority of pectate lyases%2C displays high activity on highly methylated pectins (By similarity)%3B Belongs to the polysaccharide lyase 3 family%3B KEGG: bli:BL03597 pectate lyase C gene gene3219 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03220 S100141_03221 S100141_03221 lacA lacA 2958608 2959126 - Galactoside O-acetyltransferase Acyltransferase%3B Repeat%3B Transferase%3B Belongs to the transferase hexapeptide repeat family%3B KEGG: nph:NP_4198A galactoside O-acetyltransferase gene gene3220 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03221 S100141_03222 S100141_03222 ppaX ppaX 2959123 2959770 - Inorganic diphosphatase Hydrolase%3B Magnesium%3B Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool%3B Belongs to the HAD-like hydrolase superfamily. PpaX family%3B KEGG: bli:BL03404 pyrophosphatase PpaX gene gene3221 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03222 S100141_03223 S100141_03223 S100141_03223 2959760 2960707 - putative membrane protein YvoD Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3222 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03223 S100141_03224 S100141_03224 umpA umpA 2960733 2961545 - Prolipoprotein diacylglyceryl transferase Cell membrane%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins%3B Belongs to the Lgt family%3B KEGG: bli:BL03402 phosphatidylglycerol:prolipoprotein diacylglycerol transferase%3B Transferases gene gene3223 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03224 S100141_03225 S100141_03225 hprK hprK 2961557 2962489 - HPr kinase/phosphorylase ATP-binding%3B Carbohydrate metabolism%3B Kinase%3B Magnesium%3B Metal-binding%3B Multifunctional enzyme%3B Nucleotide-binding%3B Serine/threonine-protein kinase%3B Transferase%3B Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr%2C a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing%2C inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites%2C which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose%2C fructose%2C etc.) in the growth medium. Also phosphorylates/dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore%2C by controlling the phosphorylation state of HPr and crh%2C HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR)%2C and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion%3B Belongs to the HPrK/P family%3B KEGG: bsu:BSU35000 HPr kinase/phosphorylase%3B Protein-serine/threonine kinases gene gene3224 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03225 S100141_03226 S100141_03226 S100141_03226 2962672 2963151 + putative HTH-type transcriptional regulator YfiV DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH marR-type DNA-binding domain gene gene3225 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03226 S100141_03227 S100141_03227 S100141_03227 2963291 2964850 + putative MFS-type transporter YfiU Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily. TCR/Tet family gene gene3226 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03227 S100141_03228 S100141_03228 S100141_03228 2964868 2968857 - uncharacterized protein Signal. gene gene3227 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03228 S100141_03229 S100141_03229 S100141_03229 2968955 2969314 - putative membrane protein YvlD Cell membrane%3B Membrane%3B Signal%3B Transmembrane%3B Transmembrane helix. gene gene3228 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03229 S100141_03230 S100141_03230 S100141_03230 2969311 2969511 - putative membrane protein YvlC Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3229 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03230 S100141_03231 S100141_03231 S100141_03231 2969516 2970610 - uncharacterized protein Coiled coil. gene gene3230 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03231 S100141_03232 S100141_03232 S100141_03232 2970636 2970962 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3231 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03232 S100141_03233 S100141_03233 S100141_03233 2971177 2971407 + uncharacterized protein gene gene3232 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03233 S100141_03234 S100141_03234 S100141_03234 2971640 2971783 - Virulence protein Virulence%3B Is critically involved in promoting the replication of S. typhimurium cells inside host macrophages%2C suggesting a role in the establishment of bacterial colonization within macrophages. May be involved in the biosynthesis and modification of the peptidoglycan layer of the cell wall gene gene3233 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03234 S100141_03235 S100141_03235 S100141_03235 2971927 2974800 - UvrABC system protein ATP-binding%3B Cytoplasm%3B DNA damage%3B DNA excision%3B DNA repair%3B DNA-binding%3B Excision nuclease%3B Metal-binding%3B Nucleotide-binding%3B Repeat%3B SOS response%3B Zinc%3B Zinc-finger%3B The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB%2C the UvrA molecules dissociate%3B Belongs to the ABC transporter superfamily. UvrA family%3B Contains 2 ABC transporter domains gene gene3234 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03235 S100141_03236 S100141_03236 S100141_03236 2974808 2976793 - UvrABC system protein ATP-binding%3B Cytoplasm%3B DNA damage%3B DNA excision%3B DNA repair%3B Excision nuclease%3B Nucleotide-binding%3B SOS response%3B The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site%2C the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix%2C facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found%2C the DNA wraps around the other UvrB subunit that will check the other stand for damage%3B Belongs to the UvrB family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B Contains 1 UVR domain gene gene3235 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03236 S100141_03237 S100141_03237 S100141_03237 2976977 2977210 - Protein CsbA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3236 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03237 S100141_03238 S100141_03238 S100141_03238 2977329 2977622 - hypothetical protein gene gene3237 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03238 S100141_03239 S100141_03239 S100141_03239 2977747 2978982 - Cell division topological determinant MinJ Cell cycle%3B Cell division%3B Cell membrane%3B Membrane%3B Septation%3B Transmembrane%3B Transmembrane helix%3B The main function of the Min system is to promote the disassembly of the cytokinetic ring after cell division%2C thereby ensuring that division occurs only once per cell cycle. MinJ acts as a bridge between DivIVA and MinD. May modulate activity and localization of MinD and MinC through direct interaction with MinD%3B Belongs to the MinJ family%3B Contains 1 PDZ (DHR) domain gene gene3238 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03239 S100141_03240 S100141_03240 S100141_03240 2979256 2979609 - Swarming motility protein SwrAA Cytoplasm%3B Required for swarm cell differentiation. Plays a crucial role in regulating the degree of cell flagellation gene gene3239 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03240 S100141_03241 S100141_03241 S100141_03241 2979962 2981401 - C-terminal processing peptidase Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Serine protease%3B Transmembrane%3B Transmembrane helix%3B Belongs to the peptidase S41A family%3B Contains 1 PDZ (DHR) domain%3B KEGG: bli:BL03390 carboxyl-terminal processing protease gene gene3240 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03241 S100141_03242 S100141_03242 ttuC ttuC 2981531 2982640 - Tartrate dehydrogenase Lyase%3B NAD%3B Oxidoreductase%3B Belongs to the isocitrate and isopropylmalate dehydrogenases family%3B KEGG: bli:BL03389 tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase gene gene3241 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03242 S100141_03243 S100141_03243 S100141_03243 2982745 2983995 - Golgin IMH1 Coiled coil%3B Cytoplasm%3B Golgi apparatus%3B Membrane%3B Protein transport%3B Transport%3B Involved in vesicular transport between an endosomal compartment and the Golgi apparatus%3B Contains 1 GRIP domain gene gene3242 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03243 S100141_03244 S100141_03244 S100141_03244 2984088 2984987 - Cell division protein FtsX Cell cycle%3B Cell division%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. May act as an importer%2C possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation. Acts upstream of the histidine kinases KinA%2C KinB and KinC%2C the RapA phosphatase and the Spo0A sporulation protein%3B Belongs to the ABC-4 integral membrane protein family. FtsX subfamily gene gene3243 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03244 S100141_03245 S100141_03245 S100141_03245 2984971 2985657 - Cell division ATP-binding protein FtsE ATP-binding%3B Cell cycle%3B Cell division%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter FtsEX involved in sporulation. May act as an importer%2C possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation. Acts upstream of the histidine kinases KinA%2C KinB and KinC%2C the RapA phosphatase and the Spo0A sporulation protein%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene3244 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03245 S100141_03246 S100141_03246 S100141_03246 2986010 2986336 - Cytochrome c-551 Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Lipoprotein%3B Membrane%3B Metal-binding%3B Palmitate%3B Signal%3B Transport%3B Electron carrier protein%3B Contains 1 cytochrome c domain gene gene3245 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03246 S100141_03247 S100141_03247 S100141_03247 2986385 2987239 - UPF0750 membrane protein YvjA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0750 family gene gene3246 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03247 S100141_03248 S100141_03248 S100141_03248 2987440 2988423 - Peptide chain release factor Cytoplasm%3B Methylation%3B Protein biosynthesis%3B Ribosomal frameshifting%3B Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. Belongs to the prokaryotic/mitochondrial release factor family gene gene3247 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03248 S100141_03249 S100141_03249 S100141_03249 2988604 2991129 - Protein translocase subunit SecA ATP-binding%3B Cell membrane%3B Cytoplasm%3B Membrane%3B Metal-binding%3B Nucleotide-binding%3B Protein transport%3B Translocation%3B Transport%3B Zinc%3B Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane%2C serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane%3B Belongs to the SecA family gene gene3248 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03249 S100141_03250 S100141_03250 S100141_03250 2991290 2991850 - uncharacterized protein Belongs to the ribosomal protein S30Ae family gene gene3249 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03250 S100141_03251 S100141_03251 S100141_03251 2992077 2992454 - uncharacterized protein gene gene3250 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03251 S100141_03252 S100141_03252 S100141_03252 2992464 2992805 - Flagellar protein FliT Bacterial flagellum biogenesis%3B Chaperone%3B Coiled coil%3B Cytoplasm%3B May act as an export chaperone for the filament capping protein FliD%3B Belongs to the bacillales FliT family gene gene3251 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03252 S100141_03253 S100141_03253 S100141_03253 2992805 2993206 - Flagellar protein FliS Bacterial flagellum biogenesis%3B Cytoplasm%3B Belongs to the FliS family gene gene3252 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03253 S100141_03254 S100141_03254 S100141_03254 2993228 2994709 - Flagellar hook-associated protein Bacterial flagellum%3B Coiled coil%3B Secreted%3B Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure%2C which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end (By similarity)%3B Belongs to the FliD family gene gene3253 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03254 S100141_03255 S100141_03255 S100141_03255 2994728 2995069 - uncharacterized protein gene gene3254 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03255 S100141_03256 S100141_03256 S100141_03256 2995254 2996075 - Flagellin Bacterial flagellum%3B Cell wall%3B Secreted%3B Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Belongs to the bacterial flagellin family gene gene3255 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03256 S100141_03257 S100141_03257 S100141_03257 2996208 2996432 - Carbon storage regulator like protein RNA-binding%3B Could accelerate the degradation of some genes transcripts potentially through selective RNA binding%3B Belongs to the CsrA family gene gene3256 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03257 S100141_03258 S100141_03258 S100141_03258 2996426 2996860 - Flagellar assembly factor FliW Bacterial flagellum biogenesis%3B Cytoplasm%3B Binds to the C-terminal region of flagellin%2C which is implicated in polymerization%2C and participates in the assembly of the flagellum%3B Belongs to the FliW family gene gene3257 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03258 S100141_03259 S100141_03259 S100141_03259 2996879 2997445 - uncharacterized protein gene gene3258 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03259 S100141_03260 S100141_03260 S100141_03260 2997495 2998406 - Flagellar hook-associated protein Bacterial flagellum%3B Secreted%3B Belongs to the bacterial flagellin family gene gene3259 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03260 S100141_03261 S100141_03261 S100141_03261 2998417 2999940 - Flagellar hook-associated protein Bacterial flagellum%3B Secreted%3B Belongs to the flagella basal body rod proteins family gene gene3260 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03261 S100141_03262 S100141_03262 S100141_03262 2999956 3000432 - uncharacterized protein Bacterial flagellum biogenesis%3B Phosphoprotein. gene gene3261 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03262 S100141_03263 S100141_03263 S100141_03263 3000451 3000717 - Negative regulator of flagellin synthesis Bacterial flagellum biogenesis%3B Repressor%3B Transcription%3B Transcription regulation%3B Allows the coupling of early and late flagellar synthesis through the repression of RNA polymerase sigma-D factor- dependent transcription. Belongs to the FlgM family gene gene3262 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03263 S100141_03264 S100141_03264 S100141_03264 3000797 3001216 - uncharacterized protein Bacterial flagellum biogenesis%3B May be involved in the assembly%2C structure%2C or function of the flagellum. May polymerize to form a filamentous structure that is part of the flagellum. To S. typhimurium FliF gene gene3263 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03264 S100141_03265 S100141_03265 S100141_03265 3001966 3002250 - ComF operon protein Competence. gene gene3264 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03265 S100141_03266 S100141_03266 S100141_03266 3002305 3003699 - ComF operon protein ATP-binding%3B Competence%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Involved in transformation (competence for DNA uptake). Required for DNA uptake but not for binding. May provide the driving force for transport of DNA through an aqueous channel. Belongs to the helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain gene gene3265 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03266 S100141_03267 S100141_03267 S100141_03267 3003820 3004662 - DegV domain-containing protein Lipid-binding%3B May bind long-chain fatty acids%2C such as palmitate%2C and may play a role in lipid transport or fatty acid metabolism%3B Contains 1 DegV domain gene gene3266 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03267 S100141_03268 S100141_03268 S100141_03268 3004782 3005471 - Transcriptional regulatory protein DegU Activator%3B Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Repressor%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system DegS/DegU%2C which plays an important role in the transition growth phase. Involved in the control of expression of different cellular functions%2C including production of degradative enzymes such as the neutral and alkaline proteases%2C flagellum formation%2C biofilm formation%2C and competence for DNA uptake. Positively or negatively regulates expression of many different genes. The phosphorylated form is required for synthesis of degradative enzymes%2C flagellum formation and biofilm formation. The unphosphorylated form is required for expression of genetic competence%2C via induction of comK%3B Contains 1 HTH luxR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3267 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03268 S100141_03269 S100141_03269 degS degS 3005553 3006710 - Histidine kinase ATP-binding%3B Coiled coil%3B Cytoplasm%3B Hydrolase%3B Kinase%3B Nucleotide-binding%3B Phosphoprotein%3B Protein phosphatase%3B Transferase%3B Two-component regulatory system%3B Member of the two-component regulatory system DegS/DegU%2C which plays an important role in the transition growth phase. Involved in the control of expression of different cellular functions%2C including production of degradative enzymes such as the neutral and alkaline proteases%2C flagellum formation and biofilm formation. Acts as both a protein kinase that undergoes autophosphorylation and subsequently transfers the phosphate to DegU%2C and a protein phosphatase that dephosphorylates phospho- DegU%3B Contains 1 histidine kinase domain%3B KEGG: bli:BL03360 two-component system%2C NarL family%2C sensor histidine kinase DegS gene gene3268 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03269 S100141_03270 S100141_03270 S100141_03270 3006924 3007562 + Xaa-Pro dipeptidase Belongs to the IMPACT family%3B KEGG: sph:MGAS10270_Spy1444 Xaa-Pro dipeptidase gene gene3269 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03270 S100141_03271 S100141_03271 S100141_03271 3007577 3008650 + Putative transcriptional regulator YvhJ Cell membrane%3B Membrane%3B Signal-anchor%3B Transcription%3B Transcription regulation%3B Transmembrane%3B Transmembrane helix%3B Belongs to the LytR/CpsA/Psr regulatory protein family gene gene3270 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03271 S100141_03272 S100141_03272 S100141_03272 3008735 3009109 - uncharacterized protein gene gene3271 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03272 S100141_03273 S100141_03273 wecA wecA 3009229 3010293 - UDP-N-acetylglucosamine--undecaprenyl-phosphateN-acetylglucosaminephosphotransferase Cell membrane%3B Cell wall biogenesis/degradation%3B Glycosyltransferase%3B Magnesium%3B Manganese%3B Membrane%3B Teichoic acid biosynthesis%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to the peptidoglycan of B. subtili%3B may also be involved in teichuronic acid biosynthesis (Probable)%3B Belongs to the glycosyltransferase 4 family%3B KEGG: bli:BL03358 UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase gene gene3272 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03273 S100141_03274 S100141_03274 tuaH tuaH 3010424 3011605 - Putative teichuronic acid biosynthesis glycosyltransferase TuaH Cell wall biogenesis/degradation%3B Glycosyltransferase%3B Stress response%3B Transferase%3B Belongs to the glycosyltransferase group 1 family%3B KEGG: bli:BL03357 teichuronic acid biosynthesis glycosyltransferase TuaH%3B Glycosyltransferases gene gene3273 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03274 S100141_03275 S100141_03275 tuaG tuaG 3011633 3012391 - putative glycosyltransferase Glycosyltransferase%3B Transferase%3B Belongs to the glycosyltransferase 2 family%3B KEGG: bso:BSNT_05412 teichuronic acid biosynthesis glycosyltransferase TuaG%3B Glycosyltransferases gene gene3274 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03275 S100141_03276 S100141_03276 S100141_03276 3012421 3013095 - Teichuronic acid biosynthesis protein TuaF Cell membrane%3B Cell wall biogenesis/degradation%3B Membrane%3B Stress response%3B Transmembrane%3B Transmembrane helix. gene gene3275 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03276 S100141_03277 S100141_03277 S100141_03277 3013137 3014591 - Teichuronic acid biosynthesis protein TuaE Cell membrane%3B Cell wall biogenesis/degradation%3B Membrane%3B Stress response%3B Transmembrane%3B Transmembrane helix. gene gene3276 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03277 S100141_03278 S100141_03278 galE galE 3014655 3015584 - UDP-glucose 4-epimerase Carbohydrate metabolism%3B Galactose metabolism%3B Isomerase%3B NAD%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: dji:CH75_11130 UDP-glucose 4-epimerase gene gene3277 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03278 S100141_03279 S100141_03279 ugdH ugdH 3015602 3016936 - UDP-glucose 6-dehydrogenase Cell wall biogenesis/degradation%3B Cytoplasm%3B NAD%3B Oxidoreductase%3B Phosphoprotein%3B Stress response%3B Catalyzes the conversion of UDP-glucose into UDP- glucuronate%2C one of the precursors of teichuronic acid. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family%3B KEGG: bso:BSNT_05418 UDPglucose 6-dehydrogenase gene gene3278 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03279 S100141_03280 S100141_03280 tuaC tuaC 3017131 3018309 - Putative teichuronic acid biosynthesis glycosyltransferase TuaC Cell wall biogenesis/degradation%3B Glycosyltransferase%3B Stress response%3B Transferase%3B Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: bsu:BSU35590 teichuronic acid biosynthesis glycosyltransferase TuaC%3B Glycosyltransferases gene gene3279 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03280 S100141_03281 S100141_03281 S100141_03281 3018332 3019771 - Teichuronic acid biosynthesis protein TuaB Cell membrane%3B Cell wall biogenesis/degradation%3B Membrane%3B Stress response%3B Transmembrane%3B Transmembrane helix%3B Might be involved in the translocation of teichuronic acid repeating units from the inner to the outer surface of the membrane. Belongs to the polysaccharide synthase family gene gene3280 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03281 S100141_03282 S100141_03282 S100141_03282 3019795 3020454 - Putative undecaprenyl-phosphate N-acetylgalactosaminyl 1-phosphate transferase Cell membrane%3B Cell wall biogenesis/degradation%3B Glycosyltransferase%3B Membrane%3B Stress response%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Might mediate the very first reaction in teichuronic synthesis%2C i. e. the formation of lipid-linked N-acetylglucosamine. Belongs to the bacterial sugar transferase family gene gene3281 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03282 S100141_03283 S100141_03283 S100141_03283 3020686 3022173 - N-acetylmuramoyl-L-alanine amidase Cell wall%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Repeat%3B Secreted%3B Signal%3B Autolysins are cell wall hydrolases involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella - in particular of its basal body - and sporulation. Has a high affinity for teichoic acid-endowed peptidoglycan. LytC is required for efficient swarming motility but not at the level of cell separation or flagellum biosynthesis. Rather%2C LytC appears to be important for proper flagellar function%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B KEGG: bli:BL03348 N-acetylmuramoyl-L-alanine amidase gene gene3282 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03283 S100141_03284 S100141_03284 S100141_03284 3022258 3024402 - N-acetylmuramoyl-L-alanine amidase Cell membrane%3B Cell wall%3B Cell wall biogenesis/degradation%3B Membrane%3B Repeat%3B Secreted%3B Signal%3B KEGG: csq:CSCA_5254 N-acetylmuramoyl-L-alanine amidase gene gene3283 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03284 S100141_03285 S100141_03285 S100141_03285 3024432 3024752 - Membrane-bound protein LytA Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal. gene gene3284 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03285 S100141_03286 S100141_03286 S100141_03286 3024950 3025870 + Transcriptional regulator LytR Cell membrane%3B Membrane%3B Signal-anchor%3B Transcription%3B Transcription regulation%3B Transmembrane%3B Transmembrane helix%3B Attenuator role for operon expression%3B Belongs to the LytR/CpsA/Psr regulatory protein family gene gene3285 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03286 S100141_03287 S100141_03287 wecB wecB 3026110 3027252 - UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) Cell wall biogenesis/degradation%3B Cytoplasm%3B Isomerase%3B Teichoic acid biosynthesis%3B Catalyzes the conversion of UDP-N-acetylglucosamine into UDP-N-acetylmannosamine%2C a precursor of the teichoic acid linkage unit%3B Belongs to the UDP-N-acetylglucosamine 2-epimerase family%3B KEGG: cfu:CFU_3660 UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) gene gene3286 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03287 S100141_03288 S100141_03288 ugp2 ugp2 3027629 3028507 + UTP--glucose-1-phosphate uridylyltransferase Capsule biogenesis/degradation%3B Exopolysaccharide synthesis%3B Nucleotidyltransferase%3B Transferase%3B Belongs to the UDPGP type 2 family%3B KEGG: pmr:PMI1490 UTP--glucose-1-phosphate uridylyltransferase gene gene3287 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03288 S100141_03289 S100141_03289 tagH tagH 3028578 3029489 - Teichoic-acid-transporting ATPase ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Teichoic acids exporter (TC 3. A. 1. 104. 1) family%3B Contains 1 ABC transporter domain%3B KEGG: bsu:BSU35700 teichoic acid transport system ATP-binding protein gene gene3288 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03289 S100141_03290 S100141_03290 S100141_03290 3029510 3030337 - Teichoic acid translocation permease protein TagG Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex TagGH (TC 3. A. 1. 34. 1) involved in exporting the two types of intracellularly synthesized teichoic acids. Probably responsible for the translocation of the substrate across the membrane. Belongs to the ABC-2 integral membrane protein family%3B Contains 1 ABC transmembrane type-2 domain gene gene3289 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03290 S100141_03291 S100141_03291 S100141_03291 3030681 3031994 + hypothetical protein gene gene3290 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03291 S100141_03292 S100141_03292 tagF tagF 3032339 3034915 - CDP-glycerol glycerophosphotransferase Cell membrane%3B Cell wall biogenesis/degradation%3B Glycosyltransferase%3B Membrane%3B Teichoic acid biosynthesis%3B Transferase%3B Catalyzes the addition of a second single glycerol-P residue to the prenolpyrophosphate-linked disaccharide%2C to complete the linkage unit%3B Belongs to the CDP-glycerol glycerophosphotransferase family%3B KEGG: bso:BSNT_05451 CDP-glycerol glycerophosphotransferase gene gene3291 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03292 S100141_03293 S100141_03293 S100141_03293 3035227 3037362 - CDP-glycerol glycerophosphotransferase Cell membrane%3B Cell wall biogenesis/degradation%3B Glycosyltransferase%3B Membrane%3B Teichoic acid biosynthesis%3B Transferase%3B Is responsible for the polymerization of the main chain of the major teichoic acid by sequential transfer of glycerol phosphate units from CDP-glycerol to the disaccharide linkage unit. Synthesizes polymers of approximately 35 glycerol phosphate units in length%3B Belongs to the CDP-glycerol glycerophosphotransferase family%3B KEGG: bli:BL02463 CDP-glycerol glycerophosphotransferase gene gene3292 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03293 S100141_03294 S100141_03294 tagD tagD 3037504 3037899 - Glycerol-3-phosphate cytidylyltransferase Cell wall biogenesis/degradation%3B Cobalt%3B Cytoplasm%3B Iron%3B Magnesium%3B Manganese%3B Nucleotidyltransferase%3B Teichoic acid biosynthesis%3B Transferase%3B Provides activated glycerol phosphate for teichoic acid synthesis%2C via incorporation into both the linkage unit and the teichoic acid polymer by TagB and TagF. Belongs to the cytidylyltransferase family%3B KEGG: ecc:c3696 glycerol-3-phosphate cytidylyltransferase gene gene3293 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03294 S100141_03295 S100141_03295 tagA tagA 3038255 3039037 + N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase Cell wall biogenesis/degradation%3B Glycosyltransferase%3B Secreted%3B Teichoic acid biosynthesis%3B Transferase%3B Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol%2C a key lipid intermediate in the de novo synthesis of teichoic acid%3B Belongs to the glycosyltransferase 26 family%3B KEGG: bso:BSNT_05454 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase gene gene3294 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03295 S100141_03296 S100141_03296 tarL tarL 3039057 3040220 + CDP-ribitol ribitolphosphotransferase Cell membrane%3B Cell wall biogenesis/degradation%3B Glycosyltransferase%3B Membrane%3B Teichoic acid biosynthesis%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the addition of a first single glycerol-P residue to the prenolpyrophosphate-linked disaccharide%3B Belongs to the CDP-glycerol glycerophosphotransferase family%3B KEGG: bsl:A7A1_1141 CDP-ribitol ribitolphosphotransferase gene gene3295 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03296 S100141_03297 S100141_03297 S100141_03297 3040249 3042879 - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Cell wall%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Repeat%3B Secreted%3B Signal%3B Cell wall hydrolase not involved in cell autolysis%2C competence%2C sporulation or germination. It hydrolyzes the beta-1%2C4 glycan bond between the N-acetylglucosaminyl and the N- acetylmuramoyl residues in the glycan chain%3B Belongs to the glycosyl hydrolase 73 family%3B Contains 3 SPOR domains%3B KEGG: bli:BL02465 mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase gene gene3296 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03297 S100141_03298 S100141_03298 S100141_03298 3043008 3043958 - Mannose-6-phosphate isomerase Carbohydrate metabolism%3B Isomerase%3B Metal-binding%3B Zinc%3B Belongs to the mannose-6-phosphate isomerase type 1 family%3B KEGG: bsu:BSU35790 mannose-6-phosphate isomerase gene gene3297 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03298 S100141_03299 S100141_03299 nrdG nrdG 3044114 3044626 - [Formate-C-acetyltransferase]-activating enzyme 4Fe-4S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase%3B S-adenosyl-L-methionine%3B Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical%2C using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. Belongs to the organic radical-activating enzymes family%3B KEGG: bld:BLi03823 anaerobic ribonucleoside-triphosphate reductase activating protein gene gene3298 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03299 S100141_03300 S100141_03300 nrdD nrdD 3044575 3046443 - Ribonucleoside-triphosphate reductase Metal-binding%3B Organic radical%3B Oxidoreductase%3B Zinc%3B Belongs to the anaerobic ribonucleoside-triphosphate reductase family%3B Contains 1 glycine radical domain%3B KEGG: bli:BL02468 ribonucleoside-triphosphate reductase gene gene3299 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03300 S100141_03301 S100141_03301 S100141_03301 3046611 3047597 - 2-keto-3-deoxygluconate permease Cell membrane%3B Membrane%3B Sugar transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell%2C where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)%3B Belongs to the KdgT transporter family gene gene3300 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03301 S100141_03302 S100141_03302 S100141_03302 3047682 3048296 - 2-dehydro-3-deoxy-phosphogluconate aldolase Cytoplasm%3B Lyase%3B Multifunctional enzyme%3B Schiff base%3B Belongs to the KHG/KDPG aldolase family%3B KEGG: bli:BL02470 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase gene gene3301 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03302 S100141_03303 S100141_03303 kdgK kdgK 3048302 3049267 - 2-dehydro-3-deoxygluconokinase ATP-binding%3B Carbohydrate metabolism%3B Kinase%3B Nucleotide-binding%3B Plasmid%3B Transferase%3B Involved in the degradation of glucose via the semi- phosphorylative Entner-Doudoroff pathway. Catalyzes the phosphorylation of 2-keto-3-deoxygluconate (KDG) to produce 2- keto-3-deoxy-6-phosphogluconate (KDPG)%3B Belongs to the carbohydrate kinase pfkB family%3B KEGG: bma:BMA0961 2-dehydro-3-deoxygluconokinase gene gene3302 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03303 S100141_03304 S100141_03304 S100141_03304 3049370 3050386 - putative HTH-type transcriptional regulator EndR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Putative repressor of the endoglucanase operon. Contains 1 HTH lacI-type DNA-binding domain gene gene3303 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03304 S100141_03305 S100141_03305 kduI kduI 3050642 3051469 + 5-dehydro-4-deoxy-D-glucuronate isomerase Isomerase%3B Metal-binding%3B Zinc%3B Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2%2C5-hexodiulosonate%3B Belongs to the KduI family%3B KEGG: cja:CJA_0169 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase gene gene3304 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03305 S100141_03306 S100141_03306 kduD kduD 3051485 3052249 + 2-deoxy-D-gluconate 3-dehydrogenase NAD%3B Oxidoreductase%3B Catalyzes the reversible reduction of 2%2C5-diketo-3- deoxygluconate (DKII or 4%2C6-dihydroxy-2%2C5-dioxohexanoate) into 2- keto-3-deoxygluconate (KDG or 2-dehydro-3-deoxygluconate) with a concomitant oxidation of NADH (Ref. 4). To a lesser extent%2C can also reduce 5-keto-D-gluconate and oxidize D-gluconate and 1%2C2- propanediol (PubMed:24509771). Together with KduI%2C seems to play a role in the catabolism of hexuronates under osmotic stress conditions%2C substituting for the regular hexuronate degrading enzymes UxaABC and UxuAB whose expression is repressed in these conditions (PubMed:23437267). In vitro%2C also exhibits NADH- dependent 20-ketosteroid reductase activity against eukaryotic steroid hormone 11-deoxycorticosterone (11-DOC)%2C which is converted into the product 4-pregnen-20%2C21-diol-3-one. In addition to 11-DOC%2C five other C21 steroid compounds (11-deoxycortisol%2C cortisol%2C corticosterone%2C cortisone%2C and 21-hydroxypregnenolone) are reduced by KduD%2C but steroids lacking the hydroxyl group at C21 position%2C such as pregnenolone%2C testosterone propionate%2C cortisone acetate%2C or progesterone%2C cannot be used as substrate (PubMed:24509771)%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bli:BL02435 2-deoxy-D-gluconate 3-dehydrogenase gene gene3305 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03306 S100141_03307 S100141_03307 frmA frmA 3052290 3053423 - S-(hydroxymethyl)glutathione dehydrogenase Metal-binding%3B Oxidoreductase%3B Zinc%3B Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily%3B KEGG: bsu:BSU26970 S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase gene gene3306 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03307 S100141_03308 S100141_03308 S100141_03308 3053565 3053702 + hypothetical protein gene gene3307 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03308 S100141_03309 S100141_03309 S100141_03309 3053754 3054440 - Putative metabolite transport protein YwtG Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family%3B overlaps another CDS with the same product name gene gene3308 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03309 S100141_03310 S100141_03310 S100141_03310 3054437 3055126 - Putative metabolite transport protein YwtG Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family%3B overlaps another CDS with the same product name gene gene3309 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03310 S100141_03311 S100141_03311 S100141_03311 3055425 3056381 + Putative transcriptional regulator YwtF Cell membrane%3B Membrane%3B Signal-anchor%3B Transcription%3B Transcription regulation%3B Transmembrane%3B Transmembrane helix%3B Belongs to the LytR/CpsA/Psr regulatory protein family gene gene3310 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03311 S100141_03312 S100141_03312 S100141_03312 3056571 3057431 + Putative phosphatase YcsE Hydrolase%3B Magnesium%3B Metal-binding%3B Belongs to the HAD-like hydrolase superfamily. Cof family gene gene3311 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03312 S100141_03313 S100141_03313 S100141_03313 3057482 3058726 - Gamma-DL-glutamyl hydrolase Cell wall%3B Hydrolase%3B Secreted%3B Signal%3B Cleaves%2C in an endo-type manner%2C the gamma-glutamyl bond between D-glutamate and L-glutamate of poly-gamma-glutamate (PGA). Belongs to the peptidase C40 family%3B KEGG: lfu:HR49_15335 peptidoglycan endopeptidase LytF%3B Acting on peptide bonds (peptidases) gene gene3312 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03313 S100141_03314 S100141_03314 S100141_03314 3059183 3059350 - uncharacterized protein Signal. gene gene3313 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03314 S100141_03315 S100141_03315 S100141_03315 3059347 3060516 - Capsule biosynthesis protein CapA Capsule biogenesis/degradation%3B Cell membrane%3B Membrane%3B Plasmid%3B Transmembrane%3B Transmembrane helix%3B Virulence%3B Essential for the synthesis of the polyglutamate capsule of B. anthracis which is one of the principal virulence factors during anthrax infection. May form a polyglutamyl synthetase complex together with proteins CapB and CapC. Belongs to the CapA family gene gene3314 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03315 S100141_03316 S100141_03316 S100141_03316 3060536 3060985 - Capsule biosynthesis protein CapC Capsule biogenesis/degradation%3B Cell membrane%3B Membrane%3B Plasmid%3B Transmembrane%3B Transmembrane helix%3B Virulence. gene gene3315 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03316 S100141_03317 S100141_03317 S100141_03317 3061001 3062182 - PGA synthase CapB Alternative initiation%3B Ligase%3B Catalyzes the biosynthesis of PGA (gamma-polyglutamic acid) from L-glutamate. Both the 44-kDa and the 33-kDa forms are required for PGA synthesis gene gene3316 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03317 S100141_03318 S100141_03318 S100141_03318 3062977 3063957 + Sucrose operon repressor DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Repressor for the csc operon. Binds D-fructose as an inducer (By similarity)%3B Contains 1 HTH lacI-type DNA-binding domain gene gene3317 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03318 S100141_03319 S100141_03319 rbsK rbsK 3063960 3064841 + Ribokinase ATP-binding%3B Carbohydrate metabolism%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the carbohydrate kinase PfkB family%3B KEGG: hpas:JL26_09640 ribokinase gene gene3318 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03319 S100141_03320 S100141_03320 rbsD rbsD 3064838 3065233 + D-ribose pyranase Carbohydrate metabolism%3B Cytoplasm%3B Isomerase%3B Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose%3B Belongs to the RbsD / FucU family. RbsD subfamily%3B KEGG: cvi:CV_3019 D-ribose pyranase gene gene3319 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03320 S100141_03321 S100141_03321 S100141_03321 3065271 3066752 + Sulfate/thiosulfate import ATP-binding protein CysA ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Sulfate transport%3B Transport%3B Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3. A. 1. 6) family%3B Contains 1 ABC transporter domain gene gene3320 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03321 S100141_03322 S100141_03322 S100141_03322 3066754 3067716 + Ribose transport system permease protein RbsC Cell membrane%3B Membrane%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system for ribose. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily gene gene3321 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03322 S100141_03323 S100141_03323 S100141_03323 3067731 3068645 + D-xylose-binding periplasmic protein Periplasm%3B Signal%3B Sugar transport%3B Transport%3B Involved in the high-affinity D-xylose membrane transport system. Binds with high affinity to xylose (By similarity)%3B Belongs to the bacterial solute-binding protein 2 family gene gene3322 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03323 S100141_03324 S100141_03324 alsD alsD 3068925 3069686 - Acetolactate decarboxylase Acetoin biosynthesis%3B Decarboxylase%3B Lyase%3B Converts acetolactate into acetoin%3B Belongs to the alpha-acetolactate decarboxylase family%3B KEGG: bli:BL02479 acetolactate decarboxylase gene gene3323 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03324 S100141_03325 S100141_03325 S100141_03325 3069739 3071457 - Acetolactate synthase Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B FAD%3B Flavoprotein%3B Magnesium%3B Metal-binding%3B Thiamine pyrophosphate%3B Transferase%3B Belongs to the TPP enzyme family%3B KEGG: bli:BL02480 acetolactate synthase I/II/III large subunit gene gene3324 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03325 S100141_03326 S100141_03326 S100141_03326 3071618 3072496 + HTH-type transcriptional regulator BenM Activator%3B Aromatic hydrocarbons catabolism%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Positive regulator of the ben and cat genes for benzoate degradation. BenM is necessary for ben gene expression but not for expression of the cat genes%2C which can be regulated by CatM. Binds to the inducers cis%2Ccis-muconate and benzoate. Contains 1 HTH lysR-type DNA-binding domain gene gene3325 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03326 S100141_03327 S100141_03327 S100141_03327 3072583 3074166 - Gamma-glutamyltransferase Acyltransferase%3B Hydrolase%3B Protease%3B Transferase%3B Zymogen%3B Belongs to the gamma-glutamyltransferase family%3B KEGG: bli:BL02481 gamma-glutamyltranspeptidase / glutathione hydrolase gene gene3326 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03327 S100141_03328 S100141_03328 S100141_03328 3074403 3074879 + putative HTH-type transcriptional regulator YwrC DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH asnC-type DNA-binding domain gene gene3327 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03328 S100141_03329 S100141_03329 S100141_03329 3074901 3075485 + putative transporter YwrB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the chromate ion transporter (CHR) (TC 2. A. 51) family gene gene3328 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03329 S100141_03330 S100141_03330 S100141_03330 3075482 3076018 + putative transporter YwrA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the chromate ion transporter (CHR) (TC 2. A. 51) family gene gene3329 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03330 S100141_03331 S100141_03331 S100141_03331 3076116 3076859 - Protein-tyrosine-phosphatase Capsule biogenesis/degradation%3B Exopolysaccharide synthesis%3B Hydrolase%3B Protein phosphatase%3B Required for the biosynthesis of type 1 capsular polysaccharide. Belongs to the CpsB/CapC family%3B KEGG: pfv:Psefu_1694 protein-tyrosine phosphatase gene gene3330 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03331 S100141_03332 S100141_03332 S100141_03332 3076886 3077608 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the CpsC/CapA family gene gene3331 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03332 S100141_03333 S100141_03333 S100141_03333 3077834 3077977 - uncharacterized protein gene gene3332 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03333 S100141_03334 S100141_03334 S100141_03334 3078193 3079791 + uncharacterized protein Coiled coil%3B Metal-binding%3B Zinc%3B Zinc-finger%3B Contains 1 SWIM-type zinc finger gene gene3333 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03334 S100141_03335 S100141_03335 S100141_03335 3079778 3082543 + Non-specific serine/threonine protein kinase ATP-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Belongs to the SNF2/RAD54 helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: stp:Strop_3363 non-specific serine/threonine protein kinase gene gene3334 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03335 S100141_03336 S100141_03336 S100141_03336 3082540 3082686 - hypothetical protein gene gene3335 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03336 S100141_03337 S100141_03337 S100141_03337 3082940 3083818 - Putative phosphatase Hydrolase%3B Magnesium%3B Metal-binding%3B Belongs to the HAD-like hydrolase superfamily. Cof family gene gene3336 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03337 S100141_03338 S100141_03338 S100141_03338 3083834 3084604 - HTH-type transcriptional repressor GlcR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Plays a role in carbon catabolite repression (CCR). Specifically required for transcriptional repression of the levanase operon by glucose but not by other sugars%3B Contains 1 HTH deoR-type DNA-binding domain gene gene3337 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03338 S100141_03339 S100141_03339 fsaB fsaB 3084747 3085412 - Fructose-6-phosphate aldolase Carbohydrate metabolism%3B Cytoplasm%3B Lyase%3B Schiff base%3B Catalyzes the reversible formation of fructose 6- phosphate from dihydroxyacetone and D-glyceraldehyde 3-phosphate via an aldolization reaction%3B Belongs to the transaldolase family. Type 3A subfamily%3B KEGG: bli:BL02486 fructose-6-phosphate aldolase 2%3B Aldehyde-lyases gene gene3338 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03339 S100141_03340 S100141_03340 srlD srlD 3085433 3086218 - Sorbitol-6-phosphate 2-dehydrogenase Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B NADP%3B Oxidoreductase%3B Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products%2C the first reductive step in the elongation cycle of fatty acid biosynthesis%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bli:BL02488 sorbitol-6-phosphate 2-dehydrogenase gene gene3339 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03340 S100141_03341 S100141_03341 srlB srlB 3086233 3086604 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cytoplasm%3B Kinase%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucitol/sorbitol transport. Contains 1 PTS EIIA type-5 domain%3B KEGG: bli:BL02487 PTS system%2C glucitol/sorbitol-specific IIA component gene gene3340 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03341 S100141_03342 S100141_03342 srlE srlE 3086629 3087636 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Kinase%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucitol/sorbitol transport. Contains 1 PTS EIIB type-5 domain%3B KEGG: bli:BL02489 PTS system%2C glucitol/sorbitol-specific IIB component gene gene3341 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03342 S100141_03343 S100141_03343 S100141_03343 3087654 3088202 - Glucitol/sorbitol permease IIC component Cell inner membrane%3B Cell membrane%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in glucitol/sorbitol transport. Contains 1 PTS EIIC type-5 domain gene gene3342 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03343 S100141_03344 S100141_03344 S100141_03344 3088199 3088642 - Glucitol operon activator protein Activator%3B DNA-binding%3B Phosphotransferase system%3B Transcription%3B Transcription regulation. gene gene3343 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03344 S100141_03345 S100141_03345 S100141_03345 3088639 3089601 - Sorbitol operon regulator Activator%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Positively regulates%2C in the presence of L-sorbose%2C and negatively regulates%2C in the absence of L-sorbose%2C the transcription of the sor operon. Belongs to the SorC transcriptional regulatory family gene gene3344 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03345 S100141_03346 S100141_03346 S100141_03346 3089823 3090170 - Single-stranded DNA-binding protein DNA damage%3B DNA recombination%3B DNA repair%3B DNA replication%3B DNA-binding%3B Plays an important role in DNA replication%2C recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism%3B Contains 1 SSB domain gene gene3345 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03346 S100141_03347 S100141_03347 S100141_03347 3090276 3090647 - uncharacterized protein gene gene3346 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03347 S100141_03348 S100141_03348 S100141_03348 3090829 3091242 + uncharacterized protein gene gene3347 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03348 S100141_03349 S100141_03349 S100141_03349 3091283 3091663 - Large-conductance mechanosensitive channel Cell membrane%3B Ion channel%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell%3B Belongs to the MscL family gene gene3348 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03349 S100141_03350 S100141_03350 fabZ fabZ 3091733 3092167 - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase Cytoplasm%3B Lipid A biosynthesis%3B Lipid biosynthesis%3B Lipid metabolism%3B Lyase%3B Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs%3B Belongs to the thioester dehydratase family. FabZ subfamily%3B KEGG: bli:BL02496 3-hydroxyacyl-(acyl-carrier-protein) dehydratase gene gene3349 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03350 S100141_03351 S100141_03351 S100141_03351 3092361 3093188 - Flagellar hook-basal body complex protein FlhP Bacterial flagellum biogenesis%3B Coiled coil%3B Belongs to the flagella basal body rod proteins family gene gene3350 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03351 S100141_03352 S100141_03352 S100141_03352 3093232 3094071 - Flagellar hook-basal body complex protein FlhO Bacterial flagellum biogenesis%3B Not required for motility. Belongs to the flagella basal body rod proteins family gene gene3351 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03352 S100141_03353 S100141_03353 S100141_03353 3094280 3095281 - MreB-like protein Belongs to the FtsA/MreB family gene gene3352 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03353 S100141_03354 S100141_03354 S100141_03354 3095467 3095742 - Stage III sporulation protein DNA-binding%3B Repressor%3B Sporulation%3B Transcription%3B Transcription regulation%3B This protein regulates the transcription of sigK%2C which encodes mother cell chamber RNA polymerase sigma-factor (sigma K). Contains 1 HTH deoR-type DNA-binding domain gene gene3353 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03354 S100141_03355 S100141_03355 S100141_03355 3096079 3096507 + putative HTH-type transcriptional regulator YwoH DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH marR-type DNA-binding domain gene gene3354 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03355 S100141_03356 S100141_03356 S100141_03356 3096511 3097704 + putative MFS-type transporter YwoG Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene3355 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03356 S100141_03357 S100141_03357 S100141_03357 3097854 3098432 + Undecaprenyl-diphosphate phosphatase Antibiotic resistance%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Membrane%3B Peptidoglycan synthesis%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin%3B Belongs to the BcrC/YbjG family%3B KEGG: bli:BL02453 undecaprenyl-diphosphatase gene gene3356 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03357 S100141_03358 S100141_03358 ppaC ppaC 3098475 3099404 - Inorganic diphosphatase Cytoplasm%3B Hydrolase%3B Manganese%3B Metal-binding%3B Belongs to the PPase class C family%3B KEGG: bsu:BSU40550 manganese-dependent inorganic pyrophosphatase gene gene3357 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03358 S100141_03359 S100141_03359 S100141_03359 3099539 3100360 - putative manganese catalase Calcium%3B Manganese%3B Metal-binding%3B Oxidoreductase%3B Peroxidase%3B Stress response%3B Belongs to the manganese catalase family gene gene3358 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03359 S100141_03360 S100141_03360 S100141_03360 3100490 3101227 + uncharacterized protein gene gene3359 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03360 S100141_03361 S100141_03361 S100141_03361 3101265 3101453 - IMP dehydrogenase CBS domain%3B Repeat%3B Contains 2 CBS domains%3B KEGG: bsu:BSU09230 IMP dehydrogenase gene gene3360 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03361 S100141_03362 S100141_03362 S100141_03362 3101454 3101672 - IMP dehydrogenase CBS domain%3B Repeat%3B Contains 2 CBS domains%3B KEGG: azo:azo1748 IMP dehydrogenase gene gene3361 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03362 S100141_03363 S100141_03363 S100141_03363 3101735 3102691 - Magnesium transport protein CorA Cell membrane%3B Ion transport%3B Magnesium%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mediates influx of magnesium ions%3B Belongs to the CorA metal ion transporter (MIT) (TC 1. A. 35) family gene gene3362 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03363 S100141_03364 S100141_03364 S100141_03364 3102852 3104150 + UPF0053 protein YqhB CBS domain%3B Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0053 family%3B Contains 2 CBS domains%3B Contains 1 DUF21 domain gene gene3363 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03364 S100141_03365 S100141_03365 S100141_03365 3104311 3105522 + Ammonium transporter NrgA Ammonia transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Functions as an ammonium and methylammonium transporter in the absence of glutamine. Required for ammonium utilization at low concentrations or at low pH values%2C when ammonium is the single nitrogen source. Required for binding of NrgB to the membrane%3B Belongs to the ammonia transporter channel (TC 1. A. 11. 2) family gene gene3364 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03365 S100141_03366 S100141_03366 S100141_03366 3105541 3105891 + Nitrogen regulatory PII-like protein Activator%3B Cell membrane%3B Membrane%3B Transcription%3B Transcription regulation%3B Required for full induction of the nrgAB operon under conditions of ammonium limitation%3B Belongs to the P(II) protein family gene gene3365 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03366 S100141_03367 S100141_03367 S100141_03367 3105940 3106512 - Endopeptidase Clp Cytoplasm%3B Hydrolase%3B Protease%3B Serine protease%3B Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins%3B Belongs to the peptidase S14 family%3B KEGG: dma:DMR_28170 ATP-dependent Clp protease%2C protease subunit gene gene3366 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03367 S100141_03368 S100141_03368 S100141_03368 3106526 3107131 - hypothetical protein gene gene3367 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03368 S100141_03369 S100141_03369 S100141_03369 3107268 3108143 - Stage II sporulation protein Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Involved in forespore engulfment and required for anchoring membrane proteins on the forespore side of the septal membrane. Forms a channel with SpoIIIAH that is open on the forespore end and closed (or gated) on the mother cell end. This allows sigma-E-directed gene expression in the mother-cell compartment of the sporangium to trigger the activation of sigma-G forespore-specific gene expression by a pathway of intercellular signaling gene gene3368 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03369 S100141_03370 S100141_03370 S100141_03370 3108336 3108833 + Phosphinothricin acetyltransferase Acyltransferase%3B Antibiotic resistance%3B Herbicide resistance%3B Transferase%3B This enzyme is an effector of phosphinothricin tripeptide (PTT or bialaphos) resistance. Inactivates PTT by transfer of an acetyl group (By similarity)%3B Belongs to the acetyltransferase family. PAT/BAR subfamily%3B Contains 1 N-acetyltransferase domain%3B KEGG: bli:BL04040 phosphinothricin acetyltransferase gene gene3369 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03370 S100141_03371 S100141_03371 S100141_03371 3108881 3109324 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3370 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03371 S100141_03372 S100141_03372 S100141_03372 3109556 3111022 + Major cardiolipin synthase ClsA Cell membrane%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Repeat%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol%3B Belongs to the phospholipase D family. Cardiolipin synthase subfamily%3B Contains 2 PLD phosphodiesterase domains%3B KEGG: bli:BL04039 cardiolipin synthase%3B Transferases for other substituted phosphate groups gene gene3371 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03372 S100141_03373 S100141_03373 S100141_03373 3111162 3112592 + hypothetical protein gene gene3372 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03373 S100141_03374 S100141_03374 S100141_03374 3112623 3114056 - putative transport protein HsrA Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily. EmrB family gene gene3373 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03374 S100141_03375 S100141_03375 S100141_03375 3114049 3114276 - uncharacterized protein gene gene3374 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03375 S100141_03376 S100141_03376 S100141_03376 3114289 3121446 - Dimodular nonribosomal peptide synthase Ligase%3B Phosphopantetheine%3B Phosphoprotein%3B Repeat%3B Specifically adenylates threonine and glycine%2C and loads them onto their corresponding peptidyl carrier domains%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 2 acyl carrier domains gene gene3375 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03376 S100141_03377 S100141_03377 S100141_03377 3121461 3122387 - Isochorismatase Hydrolase%3B Phosphopantetheine%3B Phosphoprotein%3B Belongs to the isochorismatase family%3B Contains 1 acyl carrier domain%3B KEGG: bli:BL04023 bifunctional isochorismate lyase / aryl carrier protein gene gene3376 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03377 S100141_03378 S100141_03378 S100141_03378 3122412 3124034 - (2%2C3-dihydroxybenzoyl)adenylate synthase ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Activation of the carboxylate group of 2%2C3-dihydroxy- benzoate (DHB)%2C via ATP-dependent PPi exchange reactions%2C to the acyladenylate. Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bli:BL04022 2%2C3-dihydroxybenzoate-AMP ligase gene gene3377 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03378 S100141_03379 S100141_03379 S100141_03379 3124048 3125238 - Isochorismate synthase Isomerase%3B Phosphoprotein%3B Belongs to the isochorismate synthase family%3B KEGG: bli:BL04021 isochorismate synthase gene gene3378 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03379 S100141_03380 S100141_03380 S100141_03380 3125263 3126033 - 2-deoxy-D-gluconate 3-dehydrogenase Lipid metabolism%3B NADP%3B Oxidoreductase%3B Catalyzes the NADPH-dependent reduction of long chain acyl-CoA (with chain lengths of 14 to 22 carbons) to the corresponding aldehyde%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: yel:LC20_03973 2-deoxy-D-gluconate 3-dehydrogenase gene gene3379 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03380 S100141_03381 S100141_03381 S100141_03381 3126264 3127112 - Ferri-bacillibactin esterase BesA Cytoplasm%3B Hydrolase%3B Serine esterase%3B Catalyzes the hydrolysis of the trilactone cycle of ferri-bacillibactin (ferri-BB) complex%2C leading to the formation of bacillibactin monomers and to cytosolic iron release%2C thus making iron available for metabolic use. Can also hydrolyze bacillibactin (BB)%2C however the catalytic efficiency for ferri-BB hydrolysis is much higher than for BB%3B Belongs to the esterase D family gene gene3380 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03381 S100141_03382 S100141_03382 S100141_03382 3127153 3128172 - Iron-uptake system permease protein FeuC Cell membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the uptake of iron. Probably responsible for the translocation of the substrate across the membrane%3B Part of the ABC transporter complex FeuABC/YusV involved in import of the catecholate siderophores bacillibactin and enterobactin%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene3381 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03382 S100141_03383 S100141_03383 S100141_03383 3128165 3129169 - Iron-uptake system permease protein FeuB Cell membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the uptake of iron. Probably responsible for the translocation of the substrate across the membrane%3B Part of the ABC transporter complex FeuABC/YusV involved in import of the catecholate siderophores bacillibactin and enterobactin%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene3382 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03383 S100141_03384 S100141_03384 S100141_03384 3129187 3130143 - Iron-uptake system-binding protein Cell membrane%3B Cytoplasm%3B Ion transport%3B Iron%3B Iron transport%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B Involved in the uptake of iron%3B Part of the ABC transporter complex FeuABC/YusV involved in import of the catecholate siderophores bacillibactin and enterobactin%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene3383 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03384 S100141_03385 S100141_03385 S100141_03385 3130235 3131830 - HTH-type transcriptional activator Btr Activator%3B Cytoplasm%3B DNA-binding%3B Transcription%3B Transcription regulation%3B In iron-limited conditions%2C activates expression of the feuABCybbA operon%2C which encodes the bacillibactin uptake system. Acts by binding directly to a conserved direct repeat element upstream of the feuA promoter. Activity is increased in the presence of bacillibactin%3B Contains 1 Fe/B12 periplasmic-binding domain%3B Contains 1 HTH araC/xylS-type DNA-binding domain gene gene3384 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03385 S100141_03386 S100141_03386 S100141_03386 3132230 3132550 + uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3385 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03386 S100141_03387 S100141_03387 S100141_03387 3132595 3133236 - uncharacterized protein gene gene3386 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03387 S100141_03388 S100141_03388 S100141_03388 3133311 3133712 - Putative HTH-type transcriptional regulator YwnA DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH rrf2-type DNA-binding domain gene gene3387 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03388 S100141_03389 S100141_03389 S100141_03389 3133884 3134423 + hypothetical protein gene gene3388 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03389 S100141_03390 S100141_03390 S100141_03390 3134304 3134783 - putative membrane protein YwmF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3389 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03390 S100141_03391 S100141_03391 moaA moaA 3134933 3135958 - Cyclic pyranopterin phosphate synthase 4Fe-4S%3B GTP-binding%3B Iron%3B Iron-sulfur%3B Lyase%3B Metal-binding%3B Molybdenum cofactor biosynthesis%3B Nucleotide-binding%3B S-adenosyl-L-methionine%3B Catalyzes%2C together with MoaC%2C the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z)%3B Belongs to the radical SAM superfamily. MoaA family%3B KEGG: bsu:BSU36700 cyclic pyranopterin phosphate synthase gene gene3390 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03391 S100141_03392 S100141_03392 S100141_03392 3135974 3136765 - Protein FdhD like protein Cytoplasm%3B Necessary for formate dehydrogenase activity%3B Belongs to the FdhD family gene gene3391 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03392 S100141_03393 S100141_03393 S100141_03393 3137027 3138289 + putative MFS-type transporter Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene3392 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03393 S100141_03394 S100141_03394 narB narB 3138322 3140673 + Ferredoxin--nitrate reductase 2Fe-2S%3B 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Molybdenum%3B NAD%3B Oxidoreductase%3B Repeat%3B In the C-terminal sectio%3B belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 2Fe-2S ferredoxin-type domain%3B Contains 2 4Fe-4S ferredoxin-type domains%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: pmx:PERMA_0888 ferredoxin-nitrate reductase gene gene3393 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03394 S100141_03395 S100141_03395 S100141_03395 3140720 3141391 - uncharacterized protein Signal%3B Contains 1 VWFA domain%3B To B. subtilis YwmD gene gene3394 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03395 S100141_03396 S100141_03396 S100141_03396 3141785 3142471 - uncharacterized protein Signal%3B Contains 1 VWFA domain%3B To B. subtilis YwmD gene gene3395 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03396 S100141_03397 S100141_03397 S100141_03397 3142789 3143805 - Stage II sporulation protein D Sporulation. gene gene3396 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03397 S100141_03398 S100141_03398 murA murA 3144003 3145313 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Cell cycle%3B Cell division%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Peptidoglycan synthesis%3B Pyruvate%3B Transferase%3B Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine%3B Belongs to the EPSP synthase family. MurA subfamily%3B KEGG: maq:Maqu_2703 UDP-N-acetylglucosamine 1-carboxyvinyltransferase gene gene3397 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03398 S100141_03399 S100141_03399 S100141_03399 3145346 3146089 - uncharacterized protein Signal. gene gene3398 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03399 S100141_03400 S100141_03400 S100141_03400 3146231 3146464 - putative membrane protein YwzB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3399 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03400 S100141_03401 S100141_03401 S100141_03401 3146848 3147243 - ATP synthase epsilon chain ATP synthesis%3B Cell inner membrane%3B Cell membrane%3B CF(1)%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Transport%3B Produces ATP from ADP in the presence of a proton gradient across the membrane%3B Belongs to the ATPase epsilon chain family gene gene3400 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03401 S100141_03402 S100141_03402 atpD atpD 3147267 3148688 - H(+)-transporting two-sector ATPase ATP synthesis%3B ATP-binding%3B Cell membrane%3B CF(1)%3B Hydrogen ion transport%3B Hydrolase%3B Ion transport%3B Membrane%3B Nucleotide-binding%3B Transport%3B Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits%3B Belongs to the ATPase alpha/beta chains family%3B KEGG: bsu:BSU36810 F-type H+-transporting ATPase subunit beta gene gene3401 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03402 S100141_03403 S100141_03403 S100141_03403 3148714 3149568 - ATP synthase gamma chain ATP synthesis%3B Cell inner membrane%3B Cell membrane%3B CF(1)%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Transport%3B Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex%3B Belongs to the ATPase gamma chain family gene gene3402 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03403 S100141_03404 S100141_03404 atpA atpA 3149657 3151165 - H(+)-transporting two-sector ATPase ATP synthesis%3B ATP-binding%3B Cell inner membrane%3B Cell membrane%3B CF(1)%3B Hydrogen ion transport%3B Hydrolase%3B Ion transport%3B Membrane%3B Nucleotide-binding%3B Transport%3B Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit%3B Belongs to the ATPase alpha/beta chains family%3B KEGG: hhm:BN341_p0008 F-type H+-transporting ATPase subunit alpha gene gene3403 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03404 S100141_03405 S100141_03405 S100141_03405 3151173 3151727 - ATP synthase subunit delta ATP synthesis%3B Cell membrane%3B CF(1)%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Transport%3B F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains%2C F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel%2C linked together by a central stalk and a peripheral stalk. During catalysis%2C ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation%3B This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction%3B Belongs to the ATPase delta chain family gene gene3404 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03405 S100141_03406 S100141_03406 S100141_03406 3151724 3152242 - ATP synthase subunit ATP synthesis%3B Cell membrane%3B CF(0)%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains%2C F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel%2C linked together by a central stalk and a peripheral stalk. During catalysis%2C ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation%3B Component of the F(0) channel%2C it forms part of the peripheral stalk%2C linking F(1) to F(0)%3B Belongs to the ATPase B chain family gene gene3405 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03406 S100141_03407 S100141_03407 S100141_03407 3152417 3152629 - ATP synthase subunit ATP synthesis%3B Cell membrane%3B CF(0)%3B Hydrogen ion transport%3B Ion transport%3B Lipid-binding%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains%2C F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel%2C linked together by a central stalk and a peripheral stalk. During catalysis%2C ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation%3B Key component of the F(0) channe%3B it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits%3B Belongs to the ATPase C chain family gene gene3406 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03407 S100141_03408 S100141_03408 S100141_03408 3152679 3153413 - ATP synthase subunit ATP synthesis%3B Cell membrane%3B CF(0)%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Key component of the proton channe%3B it plays a direct role in the translocation of protons across the membrane%3B Belongs to the ATPase A chain family gene gene3407 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03408 S100141_03409 S100141_03409 S100141_03409 3153421 3153804 - ATP synthase protein Cell membrane%3B CF(0)%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex. Belongs to the bacterial AtpI family gene gene3408 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03409 S100141_03410 S100141_03410 uprT uprT 3154205 3154834 - Uracil phosphoribosyltransferase Allosteric enzyme%3B Glycosyltransferase%3B GTP-binding%3B Magnesium%3B Nucleotide-binding%3B Transferase%3B Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate%3B Belongs to the UPRTase family%3B KEGG: bsu:BSU36890 uracil phosphoribosyltransferase gene gene3409 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03410 S100141_03411 S100141_03411 glyA glyA 3154961 3156208 - Glycine hydroxymethyltransferase Amino-acid biosynthesis%3B Cytoplasm%3B One-carbon metabolism%3B Pyridoxal phosphate%3B Transferase%3B Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines%2C thymidylate%2C methionine%2C and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids%2C producing glycine and aldehydes%2C via a retro-aldol mechanism%3B Belongs to the SHMT family%3B KEGG: bsu:BSU36900 glycine hydroxymethyltransferase gene gene3410 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03411 S100141_03412 S100141_03412 S100141_03412 3156434 3156976 - UPF0340 protein Belongs to the UPF0340 family gene gene3411 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03412 S100141_03413 S100141_03413 rpiB rpiB 3156992 3157441 - Ribose-5-phosphate isomerase Isomerase%3B Belongs to the LacAB/RpiB family%3B KEGG: bli:BL03989 ribose 5-phosphate isomerase B gene gene3412 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03413 S100141_03414 S100141_03414 S100141_03414 3157584 3158039 - Protein-tyrosine-phosphatase Hydrolase%3B Protein phosphatase%3B Catalyzes the specific dephosphorylation of phosphoarginine residues in a large number of proteins. Counteracts the protein arginine kinase McsB in vivo. Can dephosphorylate CtsR-%3B thus%2C can restore the DNA-binding ability of the CtsR repressor by reversing the McsB-mediated phosphorylation. Is the only active pArg phosphatase present in B. subtilis. Exhibits almost no activity against pSer%2C pThr%2C or pTyr peptides. Appears to play a role in B. subtilis stress resistance. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes%2C such as protein homeostasis%2C motility%2C competence%2C and stringent and stress responses%2C by regulating gene expression and protein activity%3B Belongs to the low molecular weight phosphotyrosine protein phosphatase family%3B KEGG: bsu:BSU36930 protein-tyrosine phosphatase gene gene3413 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03414 S100141_03415 S100141_03415 S100141_03415 3158190 3158750 - Putative manganese efflux pump MntP Cell membrane%3B Ion transport%3B Manganese%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably functions as a manganese efflux pump%3B Belongs to the MntP (TC 9. B. 29) family gene gene3414 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03415 S100141_03416 S100141_03416 tsaC tsaC 3158825 3159874 - L-threonylcarbamoyladenylate synthase ATP-binding%3B Cytoplasm%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase%3B tRNA processing%3B Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine%2C HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate%2C with the release of diphosphate. Is also able to catalyze the reverse reaction in vitro%2C i. e. the formation of ATP from TC-AMP and PPi%3B Belongs to the SUA5 family%3B Contains 1 YrdC-like domain%3B KEGG: bld:BLi03940 L-threonylcarbamoyladenylate synthase gene gene3415 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03416 S100141_03417 S100141_03417 S100141_03417 3160026 3160433 - uncharacterized protein gene gene3416 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03417 S100141_03418 S100141_03418 S100141_03418 3160813 3161478 - Stage II sporulation protein Sporulation. gene gene3417 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03418 S100141_03419 S100141_03419 S100141_03419 3161598 3162782 - Glucose/mannose transporter GlcP Cell membrane%3B Membrane%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Can transport glucose%2C mannose%2C 2-deoxyglucose and methyl alpha-glucoside%2C but not galactose%3B Belongs to the major facilitator superfamily gene gene3418 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03419 S100141_03420 S100141_03420 ntdC ntdC 3162859 3163905 - Glucose-6-phosphate 3-dehydrogenase Antibiotic biosynthesis%3B NAD%3B Oxidoreductase%3B Involved in the biosynthesis of kanosamine (3-amino-3- deoxy-D-glucose)%2C which is known to have antibiotic and antifungal properties%2C and to be a precursor of the antibiotic neotrehalosadiamine (3%2C3'-diamino-3%2C3'-dideoxy-alpha%2Cbeta- trehalose (NTD)). Catalyzes the oxidation of glucose 6-phosphate to 3-oxo-D-glucose 6-phosphate. It can only use NAD%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: bli:BL03982 glucose-6-phosphate 3-dehydrogenase gene gene3419 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03420 S100141_03421 S100141_03421 ntdB ntdB 3163919 3164767 - Kanosamine-6-phosphate phosphatase Antibiotic biosynthesis%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Involved in the biosynthesis of kanosamine (3-amino-3- deoxy-D-glucose)%2C which is known to have antibiotic and antifungal properties%2C and to be a precursor of the antibiotic neotrehalosadiamine (3%2C3'-diamino-3%2C3'-dideoxy-alpha%2Cbeta- trehalose (NTD)). Catalyzes the dephosphorylation of kanosamine 6- phosphate to yield kanosamine. There is a trace amount of activity using glucosamine-6-phosphate%3B Belongs to the HAD-like hydrolase superfamily. Cof family%3B KEGG: bli:BL03981 kanosamine-6-phosphate phosphatase gene gene3420 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03421 S100141_03422 S100141_03422 ntdA ntdA 3164754 3166106 - 3-dehydro-glucose-6-phosphate--glutamate transaminase Aminotransferase%3B Antibiotic biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Involved in the biosynthesis of kanosamine (3-amino-3- deoxy-D-glucose)%2C which is known to have antibiotic and antifungal properties%2C and to be a precursor of the antibiotic neotrehalosadiamine (3%2C3'-diamino-3%2C3'-dideoxy-alpha%2Cbeta- trehalose (NTD)). Catalyzes the reversible pyridoxal phosphate- dependent transamination of 3-dehydro-alpha-D-glucose 6-phosphate to form alpha-D-kanosamine-6-phosphate. It can only use alpha- anomer and glutamate is the only amino donor%3B Belongs to the DegT/DnrJ/EryC1 family%3B KEGG: bli:BL03980 3-dehydro-glucose-6-phosphate---glutamate transaminase gene gene3421 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03422 S100141_03423 S100141_03423 S100141_03423 3166174 3167163 + NTD biosynthesis operon regulator NtdR Activator%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Positively regulates the ntdABC operon and negatively regulates its own transcription. Binds to NTD to induce ntdABC transcription%3B Contains 1 HTH lacI-type DNA-binding domain gene gene3422 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03423 S100141_03424 S100141_03424 hemK hemK 3167496 3168362 - Peptide chain release factor N(5)-glutamine methyltransferase Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif%3B Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily%3B KEGG: bsu:BSU37000 release factor glutamine methyltransferase gene gene3423 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03424 S100141_03425 S100141_03425 S100141_03425 3168365 3169435 - Peptide chain release factor Cytoplasm%3B Methylation%3B Protein biosynthesis%3B Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA%3B Belongs to the prokaryotic/mitochondrial release factor family gene gene3424 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03425 S100141_03426 S100141_03426 S100141_03426 3169571 3169954 + uncharacterized protein gene gene3425 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03426 S100141_03427 S100141_03427 S100141_03427 3170090 3170650 + Chromosome-anchoring protein RacA Cell cycle%3B Cell division%3B Chromosome partition%3B Coiled coil%3B Cytoplasm%3B DNA-binding%3B Sporulation%3B Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells%2C thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome%2C causing condensation of the chromosome and its remodeling into an elongated%2C anchored structure%3B Belongs to the RacA family gene gene3426 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03427 S100141_03428 S100141_03428 S100141_03428 3170705 3171661 - putative transporter YwkB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the auxin efflux carrier (TC 2. A. 69) family gene gene3427 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03428 S100141_03429 S100141_03429 S100141_03429 3171840 3173543 - Malate dehydrogenase (oxaloacetate-decarboxylating) Metal-binding%3B NAD%3B Oxidoreductase%3B Belongs to the malic enzymes family%3B KEGG: bsu:BSU37050 malate dehydrogenase (oxaloacetate-decarboxylating) gene gene3428 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03429 S100141_03430 S100141_03430 S100141_03430 3173882 3174466 - Thymidine kinase ATP-binding%3B Cytoplasm%3B DNA synthesis%3B Kinase%3B Metal-binding%3B Nucleotide-binding%3B Transferase%3B Zinc%3B Belongs to the thymidine kinase family%3B KEGG: bsu:BSU37060 thymidine kinase gene gene3429 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03430 S100141_03431 S100141_03431 S100141_03431 3174545 3174745 - 50S ribosomal protein L31 Metal-binding%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Zinc%3B Binds the 23S rRNA%3B Belongs to the ribosomal protein L31P family. Type A subfamily gene gene3430 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03431 S100141_03432 S100141_03432 S100141_03432 3174873 3176156 - Transcription termination factor Rho ATP-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B RNA-binding%3B Transcription%3B Transcription regulation%3B Transcription termination%3B Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA%2C activation of Rho's RNA-dependent ATPase activity%2C and release of the mRNA from the DNA template%3B Belongs to the Rho family gene gene3431 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03432 S100141_03433 S100141_03433 glpX glpX 3176618 3177583 - Fructose-bisphosphatase Calvin cycle%3B Carbohydrate metabolism%3B Hydrolase%3B Manganese%3B Metal-binding%3B Catalyzes the hydrolysis of fructose 1%2C6-bisphosphate (Fru 1%2C6-P2) and sedoheptulose 1%2C7-bisphosphate (Sed 1%2C7-P2) to fructose 6-phosphate and sedoheptulose 7-phosphate%2C respectively%3B Belongs to the FBPase class 2 family%3B KEGG: hap:HAPS_0273 fructose-1%2C6-bisphosphatase II gene gene3432 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03433 S100141_03434 S100141_03434 S100141_03434 3177650 3178939 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Cell cycle%3B Cell division%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Peptidoglycan synthesis%3B Pyruvate%3B Transferase%3B Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine%3B Belongs to the EPSP synthase family. MurA subfamily%3B KEGG: bsu:BSU37100 UDP-N-acetylglucosamine 1-carboxyvinyltransferase gene gene3433 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03434 S100141_03435 S100141_03435 talA talA 3179197 3179832 - Transaldolase Cytoplasm%3B Pentose shunt%3B Schiff base%3B Transferase%3B Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway%3B Belongs to the transaldolase family. Type 3B subfamily%3B KEGG: spiu:SPICUR_04415 transaldolase gene gene3434 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03435 S100141_03436 S100141_03436 fbaA fbaA 3180065 3180922 - Fructose-bisphosphate aldolase Glycolysis%3B Lyase%3B Metal-binding%3B Phosphoprotein%3B Sporulation%3B Zinc%3B Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1%2C6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis%3B Belongs to the class II fructose-bisphosphate aldolase family%3B KEGG: bsu:BSU37120 fructose-bisphosphate aldolase%2C class II gene gene3435 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03436 S100141_03437 S100141_03437 S100141_03437 3181125 3181499 - DNA-binding response regulator MtrA DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system MtrA/MtrB%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3436 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03437 S100141_03438 S100141_03438 S100141_03438 3181676 3182206 + uncharacterized protein gene gene3437 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03438 S100141_03439 S100141_03439 S100141_03439 3182250 3182381 + hypothetical protein gene gene3438 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03439 S100141_03440 S100141_03440 S100141_03440 3182403 3182735 + hypothetical protein gene gene3439 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03440 S100141_03441 S100141_03441 S100141_03441 3182705 3183565 + putative transposase-like protein DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene3440 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03441 S100141_03442 S100141_03442 pyrG pyrG 3183628 3185235 - CTP synthase (glutamine hydrolyzing) ATP-binding%3B Glutamine amidotransferase%3B Ligase%3B Nucleotide-binding%3B Pyrimidine biosynthesis%3B Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen%3B Belongs to the CTP synthase family%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: sbw:TGUWTKB_3070 CTP synthase gene gene3441 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03442 S100141_03443 S100141_03443 S100141_03443 3185490 3186005 - putative DNA-directed RNA polymerase subunit delta DNA-directed RNA polymerase%3B Nucleotidyltransferase%3B Transcription%3B Transferase%3B Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit%2C RNAP displays an increased specificity of transcription%2C a decreased affinity for nucleic acids%2C and an increased efficiency of RNA synthesis because of enhanced recycling%3B Belongs to the RpoE family gene gene3442 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03443 S100141_03444 S100141_03444 S100141_03444 3186307 3187446 - Acyl-CoA dehydrogenase FAD%3B Fatty acid metabolism%3B Flavoprotein%3B Lipid degradation%3B Lipid metabolism%3B Oxidoreductase%3B Involved in the degradation of long-chain fatty acids. Belongs to the acyl-CoA dehydrogenase family%3B KEGG: rme:Rmet_5425 null%3B With other acceptors gene gene3443 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03444 S100141_03445 S100141_03445 S100141_03445 3187468 3188598 - Acyl-CoA dehydrogenase FAD%3B Flavoprotein%3B Oxidoreductase%3B Sporulation%3B Belongs to the acyl-CoA dehydrogenase family%3B KEGG: bli:BL03927 null%3B With other acceptors gene gene3444 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03445 S100141_03446 S100141_03446 paaH paaH 3188611 3189474 - 3-hydroxybutyryl-CoA dehydrogenase Fatty acid metabolism%3B Lipid metabolism%3B NADP%3B Oxidoreductase%3B Belongs to the 3-hydroxyacyl-CoA dehydrogenase family%3B KEGG: bli:BL03926 3-hydroxybutyryl-CoA dehydrogenase gene gene3445 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03446 S100141_03447 S100141_03447 S100141_03447 3189490 3190668 - Acetyl-CoA C-acetyltransferase Acyltransferase%3B Transferase%3B Belongs to the thiolase family%3B KEGG: bli:BL03925 acetyl-CoA C-acetyltransferase gene gene3446 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03447 S100141_03448 S100141_03448 S100141_03448 3190766 3192880 - uncharacterized protein Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Contains 2 4Fe-4S ferredoxin-type domains%3B KEGG: gfo:GFO_1637 null%3B Oxidoreductases gene gene3447 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03448 S100141_03449 S100141_03449 S100141_03449 3193030 3194220 + Minor cardiolipin synthase ClsB Cell membrane%3B Membrane%3B Repeat%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Involved in the biosynthesis of cardiolipin%3B Belongs to the phospholipase D family. Cardiolipin synthase subfamily%3B Contains 2 PLD phosphodiesterase domains%3B KEGG: bli:BL03965 cardiolipin synthase%3B Transferases for other substituted phosphate groups gene gene3448 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03449 S100141_03450 S100141_03450 S100141_03450 3194295 3194561 + uncharacterized protein gene gene3449 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03450 S100141_03451 S100141_03451 rarS rarS 3194646 3196316 - Arginine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: bli:BL03923 arginyl-tRNA synthetase gene gene3450 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03451 S100141_03452 S100141_03452 S100141_03452 3196313 3196807 - putative beta-barrel protein YwiB gene gene3451 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03452 S100141_03453 S100141_03453 speB speB 3196899 3197771 - Agmatinase Hydrolase%3B Manganese%3B Metal-binding%3B Polyamine biosynthesis%3B Putrescine biosynthesis%3B Spermidine biosynthesis%3B Catalyzes the formation of putrescine from agmatine%3B Belongs to the arginase family. Agmatinase subfamily%3B KEGG: bsu:BSU37490 agmatinase gene gene3452 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03453 S100141_03454 S100141_03454 speE speE 3197826 3198656 - Spermidine synthase Cytoplasm%3B Polyamine biosynthesis%3B Spermidine biosynthesis%3B Transferase%3B Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1%2C4-diaminobutane) to yield spermidine%3B Belongs to the spermidine/spermine synthase family%3B Contains 1 PABS (polyamine biosynthesis) domain%3B KEGG: bli:BL03920 spermidine synthase gene gene3453 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03454 S100141_03455 S100141_03455 S100141_03455 3198911 3199633 + hypothetical protein gene gene3454 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03455 S100141_03456 S100141_03456 S100141_03456 3199761 3201836 + Penicillin-binding protein 2D Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Peptidoglycan synthesis%3B Signal-anchor%3B Transmembrane%3B Transmembrane helix%3B Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall%2C the first layer of peptidoglycan synthesized on the surface of the inner forespore membrane%3B In the N-terminal sectio%3B belongs to the glycosyltransferase 51 family%3B In the C-terminal sectio%3B belongs to the transpeptidase family gene gene3455 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03456 S100141_03457 S100141_03457 S100141_03457 3201894 3202409 - uncharacterized protein gene gene3456 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03457 S100141_03458 S100141_03458 S100141_03458 3202422 3203111 - Putative zinc metalloprotease YwhC Cell membrane%3B Hydrolase%3B Membrane%3B Metal-binding%3B Metalloprotease%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Zinc%3B Belongs to the peptidase M50B family gene gene3457 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03458 S100141_03459 S100141_03459 praC praC 3203192 3203377 + 2-hydroxymuconate tautomerase Isomerase%3B Belongs to the 4-oxalocrotonate tautomerase family%3B KEGG: bli:BL03961 4-oxalocrotonate tautomerase gene gene3458 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03459 S100141_03460 S100141_03460 S100141_03460 3203421 3204227 - hypothetical protein gene gene3459 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03460 S100141_03461 S100141_03461 S100141_03461 3204414 3204917 - uncharacterized protein gene gene3460 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03461 S100141_03462 S100141_03462 S100141_03462 3204948 3206246 - uncharacterized protein Contains 1 HD domain gene gene3461 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03462 S100141_03463 S100141_03463 S100141_03463 3206486 3206710 - UPF0741 protein Belongs to the UPF0741 family gene gene3462 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03463 S100141_03464 S100141_03464 S100141_03464 3206933 3207718 + Prespore-specific transcriptional regulator RsfA Activator%3B DNA-binding%3B Repressor%3B Sporulation%3B Transcription%3B Transcription regulation%3B Seems to improve the efficiency of sporulation by fine- tuning the expression of genes in the sigma F regulon%2C particularly the timing of their expression. Negatively regulates spoIIR and its own synthesis. Contains 1 Myb-like domain gene gene3463 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03464 S100141_03465 S100141_03465 S100141_03465 3207899 3208228 + uncharacterized protein Membrane%3B Signal%3B Transmembrane%3B Transmembrane helix. gene gene3464 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03465 S100141_03466 S100141_03466 lipL lipL 3208383 3209333 - Octanoyl-[GcvH]:protein N-octanoyltransferase Acyltransferase%3B Transferase%3B Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes%3B Belongs to the octanoyltransferase LipL family%3B Contains 1 BPL/LPL catalytic domain%3B KEGG: bli:BL03912 octanoyl-(GcvH):protein N-octanoyltransferase gene gene3465 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03466 S100141_03467 S100141_03467 pobA pobA 3209330 3210535 - 4-hydroxybenzoate 3-monooxygenase Aromatic hydrocarbons catabolism%3B FAD%3B Flavoprotein%3B Monooxygenase%3B NADP%3B Oxidoreductase%3B KEGG: efe:EFER_4403 p-hydroxybenzoate 3-monooxygenase gene gene3466 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03467 S100141_03468 S100141_03468 S100141_03468 3210551 3211927 - Benzoate transport protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probable uptake of benzoate. Belongs to the major facilitator superfamily. Aromatic acid:H(+) symporter (AAHS) (TC 2. A. 1. 15) family gene gene3467 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03468 S100141_03469 S100141_03469 hpaD hpaD 3211966 3212817 - 3%2C4-dihydroxyphenylacetate 2%2C3-dioxygenase Aromatic hydrocarbons catabolism%3B Dioxygenase%3B Iron%3B Oxidoreductase%3B KEGG: bli:BL03909 3%2C4-dihydroxyphenylacetate 2%2C3-dioxygenase gene gene3468 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03469 S100141_03470 S100141_03470 S100141_03470 3212841 3213032 - 2-hydroxymuconate tautomerase Isomerase%3B Belongs to the 4-oxalocrotonate tautomerase family%3B KEGG: ror:RORB6_15955 4-oxalocrotonate tautomerase gene gene3469 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03470 S100141_03471 S100141_03471 dmpH dmpH 3213050 3213835 - 2-oxo-3-hexenedioate decarboxylase Aromatic hydrocarbons catabolism%3B Lyase%3B Plasmid%3B Belongs to the hydratase/decarboxylase family%3B KEGG: bli:BL03907 2-oxo-3-hexenedioate decarboxylase gene gene3470 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03471 S100141_03472 S100141_03472 dmpC dmpC 3213850 3215334 - Aminomuconate-semialdehyde dehydrogenase Cytoplasm%3B NAD%3B Oxidoreductase%3B Ubl conjugation%3B Involved in ferulic acid and sinapic acid biosynthesis by oxidation of conyferylaldehyde and sinapaldehyde%2C respectively. Can oxidize L-lactaldehyde. Possesses activity on acetaldehyde and glycolaldehyde in vitro%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: bli:BL03906 aminomuconate-semialdehyde/2-hydroxymuconate-6-semialdehyde dehydrogenase gene gene3471 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03472 S100141_03473 S100141_03473 S100141_03473 3215527 3216306 + Glycerol operon regulatory protein Activator%3B DNA-binding%3B Glycerol metabolism%3B Transcription%3B Transcription regulation%3B May be an activator protein for the gylABX operon. Contains 1 HTH iclR-type DNA-binding domain%3B Contains 1 iclR-ED (iclR effector binding) domain gene gene3472 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03473 S100141_03474 S100141_03474 S100141_03474 3216325 3217275 + 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase Decarboxylase%3B Lyase%3B Metal-binding%3B Zinc%3B Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA)%2C a key precursor of NAD%2C and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD%2C ACMS is converted to AMS%2C a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway (By similarity)%3B Belongs to the ACMSD family gene gene3473 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03474 S100141_03475 S100141_03475 S100141_03475 3217319 3218290 - Phosphate acetyltransferase Acyltransferase%3B Cytoplasm%3B Transferase%3B Belongs to the phosphate acetyltransferase and butyryltransferase family%3B KEGG: bsu:BSU37660 phosphate acetyltransferase gene gene3474 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03475 S100141_03476 S100141_03476 S100141_03476 3218580 3219344 + Chlorite O(2)-lyase Heme%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Peroxidase%3B May function as heme-dependent peroxidase%3B Belongs to the UPF0447 family%3B KEGG: bsr:I33_3915 chlorite dismutase gene gene3475 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03476 S100141_03477 S100141_03477 S100141_03477 3219393 3219935 - uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix%3B Required for complex colony architecture gene gene3476 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03477 S100141_03478 S100141_03478 S100141_03478 3220352 3221698 + Ktr system potassium uptake protein Cell membrane%3B Ion transport%3B Membrane%3B Potassium%3B Potassium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Integral membrane subunit of the KtrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress%3B Belongs to the TrkH potassium transport family. Ktr (TC 2. A. 38. 4) subfamily gene gene3477 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03478 S100141_03479 S100141_03479 S100141_03479 3221935 3222462 + Spore coat protein GerQ Germination%3B Isopeptide bond%3B Sporulation%3B Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA gene gene3478 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03479 S100141_03480 S100141_03480 S100141_03480 3222503 3223648 - Putative transport permease YfiN Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the ABC-2 integral membrane protein family%3B Contains 1 ABC transmembrane type-2 domain gene gene3479 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03480 S100141_03481 S100141_03481 S100141_03481 3223650 3224771 - hypothetical protein gene gene3480 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03481 S100141_03482 S100141_03482 S100141_03482 3224788 3225723 - Polyamine-transporting ATPase ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3. A. 1. 11. 1) family%3B Contains 1 ABC transporter domain%3B KEGG: rme:Rmet_4399 spermidine/putrescine transport system ATP-binding protein gene gene3481 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03482 S100141_03483 S100141_03483 S100141_03483 3225827 3226933 - Sensor histidine kinase YfiJ ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system YfiJ/YfiK. Probably activates YfiK by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bcz:BCZK1607 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene3482 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03483 S100141_03484 S100141_03484 cheB cheB 3226948 3227619 - Protein-glutamate methylesterase Chemotaxis%3B Cytoplasm%3B Hydrolase%3B Phosphoprotein%3B Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain%3B KEGG: tbe:Trebr_0103 two-component system%2C chemotaxis family%2C response regulator CheB gene gene3483 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03484 S100141_03485 S100141_03485 S100141_03485 3227745 3228122 - Proline--tRNA ligase Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0382 family%3B KEGG: gsl:Gasu_24190 prolyl-tRNA synthetase gene gene3484 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03485 S100141_03486 S100141_03486 S100141_03486 3228184 3229485 - Putative purine permease YwdJ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2. A. 40) subfamily gene gene3485 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03486 S100141_03487 S100141_03487 S100141_03487 3229525 3229833 - uncharacterized protein gene gene3486 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03487 S100141_03488 S100141_03488 S100141_03488 3230105 3231487 + Aldehyde dehydrogenase (NAD(+)) Acetylation%3B Cytoplasm%3B NAD%3B NADP%3B Oxidoreductase%3B ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids%2C biogenic amines%2C neurotransmitters%2C and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes (By similarity)%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: bli:BL03952 aldehyde dehydrogenase (NAD+) gene gene3487 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03488 S100141_03489 S100141_03489 S100141_03489 3231535 3232212 - Uracil-DNA glycosylase Cytoplasm%3B DNA damage%3B DNA repair%3B Glycosidase%3B Hydrolase%3B Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine%3B Belongs to the uracil-DNA glycosylase family%3B KEGG: bsu:BSU37970 uracil-DNA glycosylase gene gene3488 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03489 S100141_03490 S100141_03490 S100141_03490 3232226 3233044 - putative glycosyltransferase YwdF Glycosyltransferase%3B Transferase%3B Belongs to the glycosyltransferase 2 family gene gene3489 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03490 S100141_03491 S100141_03491 pdxK pdxK 3233282 3234094 + Pyridoxal kinase ATP-binding%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Transferase%3B Phosphorylates B6 vitamer%3B functions in a salvage pathway. Uses pyridoxal%2C pyridoxine%2C and pyridoxamine as substrates. Can also use hydroxymethylpyrimidine (HMP) as substrate%3B Belongs to the ThiD family%3B KEGG: bsu:BSU38020 pyridoxine kinase gene gene3490 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03491 S100141_03492 S100141_03492 S100141_03492 3234128 3234466 - hypothetical protein gene gene3491 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03492 S100141_03493 S100141_03493 sacA sacA 3234483 3235919 - Beta-fructofuranosidase Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Belongs to the glycosyl hydrolase 32 family%3B KEGG: bli:BL03892 beta-fructofuranosidase gene gene3492 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03493 S100141_03494 S100141_03494 scrA scrA 3235937 3237316 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Kinase%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in sucrose transport (By similarity)%3B Acts as both a kinase and a phosphatase on SacT%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bli:BL03890 PTS system%2C sucrose-specific IIB component gene gene3493 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03494 S100141_03495 S100141_03495 S100141_03495 3237562 3238401 - SacPA operon antiterminator Activator%3B Phosphoprotein%3B Repeat%3B RNA-binding%3B Transcription%3B Transcription regulation%3B Mediates positive regulation of the sacPA operon by functioning as an antiterminator factor of transcription. Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains gene gene3494 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03495 S100141_03496 S100141_03496 S100141_03496 3238435 3238725 - hypothetical protein gene gene3495 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03496 S100141_03497 S100141_03497 S100141_03497 3238877 3239089 + hypothetical protein gene gene3496 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03497 S100141_03498 S100141_03498 S100141_03498 3239206 3241626 + Minor extracellular protease vpr Hydrolase%3B Protease%3B Secreted%3B Serine protease%3B Signal%3B Zymogen%3B Not required for growth or sporulation. Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bli:BL03950 minor extracellular serine protease Vpr%3B Serine endopeptidases gene gene3497 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03498 S100141_03499 S100141_03499 S100141_03499 3241750 3241998 + hypothetical protein gene gene3498 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03499 S100141_03500 S100141_03500 S100141_03500 3241995 3243002 - uncharacterized protein To bacterial alkanal monooxygenase alpha and beta chains gene gene3499 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03500 S100141_03501 S100141_03501 S100141_03501 3243089 3243226 + hypothetical protein gene gene3500 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03501 S100141_03502 S100141_03502 S100141_03502 3243255 3244004 - FMN reductase (NADPH) Flavoprotein%3B FMN%3B Luminescence%3B NADP%3B Oxidoreductase%3B Involved in bioluminescence. It is a good supplier of reduced flavin mononucleotide (FMNH2) to the bioluminescence reaction. Belongs to the flavin oxidoreductase frp family%3B KEGG: bli:BL03887 FMN reductase (NADPH) gene gene3501 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03502 S100141_03503 S100141_03503 hipO hipO 3244149 3245324 + Hippurate hydrolase Cobalt%3B Hydrolase%3B Metal-binding%3B Zinc%3B Belongs to the peptidase M20A family%3B KEGG: brh:RBRH_03274 hippurate hydrolase gene gene3502 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03503 S100141_03504 S100141_03504 S100141_03504 3245352 3246521 - Rod shape-determining protein RodA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Required for the maintenance of the rod cell shape. Also essential for the elongation of the lateral wall of the cell%3B Belongs to the SEDS family. RodA subfamily gene gene3503 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03504 S100141_03505 S100141_03505 S100141_03505 3246633 3247817 - Rod shape-determining protein RodA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Required for the maintenance of the rod cell shape. Also essential for the elongation of the lateral wall of the cell%3B Belongs to the SEDS family. RodA subfamily gene gene3504 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03505 S100141_03506 S100141_03506 S100141_03506 3248096 3249451 + uncharacterized protein gene gene3505 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03506 S100141_03507 S100141_03507 S100141_03507 3249441 3249623 - hypothetical protein gene gene3506 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03507 S100141_03508 S100141_03508 S100141_03508 3249875 3250135 + Spore morphoproteinis and germination protein YwcE Cell membrane%3B Germination%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Required for proper spore morphogenesis. Important for spore germination (By similarity)%3B Belongs to the YwcE family gene gene3507 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03508 S100141_03509 S100141_03509 S100141_03509 3250183 3251382 - hypothetical protein gene gene3508 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03509 S100141_03510 S100141_03510 S100141_03510 3251400 3251855 - putative N-acetyltransferase YfmK Acyltransferase%3B Transferase%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain gene gene3509 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03510 S100141_03511 S100141_03511 S100141_03511 3251867 3253675 - ABC transporter B family member 23%2C mitochondrial ATP-binding%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Mitochondrion%3B Mitochondrion inner membrane%3B Nucleotide-binding%3B Transit peptide%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Performs an essential function in the generation of cytoplasmic iron-sulfur proteins by mediating export of Fe/S cluster precursors synthesized by NFS1 and other mitochondrial proteins. Not involved in the export of cyclic pyranopterin monophosphate (cPMP) from mitochondria into the cytosol%3B Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3. A. 1. 210) subfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene3510 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03511 S100141_03512 S100141_03512 S100141_03512 3253669 3255618 - putative anion import ATP-binding protein ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of an ABC transporter complex involved in anions import (Probable). Responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene3511 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03512 S100141_03513 S100141_03513 S100141_03513 3255637 3257637 - Asparagine synthase (glutamine-hydrolyzing) KEGG: blh:BaLi_c40470 asparagine synthase (glutamine-hydrolysing) gene gene3512 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03513 S100141_03514 S100141_03514 S100141_03514 3257634 3258098 - hypothetical protein gene gene3513 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03514 S100141_03515 S100141_03515 S100141_03515 3258098 3258370 - hypothetical protein gene gene3514 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03515 S100141_03516 S100141_03516 S100141_03516 3258721 3259353 - Response regulator GacA Activator%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Involved in the regulation of secondary metabolism. Involved in the synthesis of the antifungal factors cyanide and 2%2C4-diacetylphloroglucinol. Contains 1 HTH luxR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3515 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03516 S100141_03517 S100141_03517 S100141_03517 3259525 3259641 + hypothetical protein gene gene3516 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03517 S100141_03518 S100141_03518 qoxD qoxD 3259696 3260061 - Menaquinol oxidase (H(+)-transporting) Cell membrane%3B Membrane%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth. Belongs to the cytochrome c oxidase bacterial subunit 4 family%3B KEGG: bli:BL03874 cytochrome aa3-600 menaquinol oxidase subunit IV%3B overlaps another CDS with the same product name gene gene3517 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03518 S100141_03519 S100141_03519 qoxC qoxC 3260061 3260675 - Menaquinol oxidase (H(+)-transporting) Cell membrane%3B Membrane%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth. Belongs to the cytochrome c oxidase subunit 3 family%3B KEGG: bli:BL03873 cytochrome aa3-600 menaquinol oxidase subunit III%3B overlaps another CDS with the same product name gene gene3518 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03519 S100141_03520 S100141_03520 qoxB qoxB 3260690 3262639 - Menaquinol oxidase (H(+)-transporting) Cell membrane%3B Copper%3B Electron transport%3B Heme%3B Hydrogen ion transport%3B Ion transport%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Respiratory chain%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth. Belongs to the heme-copper respiratory oxidase family%3B KEGG: bli:BL03872 cytochrome aa3-600 menaquinol oxidase subunit I gene gene3519 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03520 S100141_03521 S100141_03521 qoxA qoxA 3262657 3263625 - Menaquinol oxidase (H(+)-transporting) Cell membrane%3B Electron transport%3B Lipoprotein%3B Membrane%3B Oxidoreductase%3B Palmitate%3B Respiratory chain%3B Signal%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I. Belongs to the cytochrome c oxidase subunit 2 family%3B KEGG: bld:BLi04040 cytochrome aa3-600 menaquinol oxidase subunit II gene gene3520 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03521 S100141_03522 S100141_03522 S100141_03522 3264097 3265086 - UDP-glucose 4-epimerase Carbohydrate metabolism%3B Galactose metabolism%3B Isomerase%3B NAD%3B Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD (By similarity)%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: ecl:EcolC_3183 UDP-glucose 4-epimerase gene gene3521 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03522 S100141_03523 S100141_03523 S100141_03523 3265889 3266038 + hypothetical protein gene gene3522 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03523 S100141_03524 S100141_03524 S100141_03524 3266209 3266427 - hypothetical protein gene gene3523 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03524 S100141_03525 S100141_03525 S100141_03525 3266580 3266819 + Putative NAD(P)H-dependent FMN-containing oxidoreductase YwqN Flavoprotein%3B FMN%3B NAD%3B NADP%3B Oxidoreductase%3B Putative NADPH-dependent oxidoreductase%3B Belongs to the SsuE family gene gene3524 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03525 S100141_03526 S100141_03526 S100141_03526 3266838 3267149 + Putative NAD(P)H-dependent FMN-containing oxidoreductase YwqN Flavoprotein%3B FMN%3B NAD%3B NADP%3B Oxidoreductase%3B Putative NADPH-dependent oxidoreductase%3B Belongs to the SsuE family gene gene3525 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03526 S100141_03527 S100141_03527 S100141_03527 3267318 3267632 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3526 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03527 S100141_03528 S100141_03528 S100141_03528 3267629 3269167 + putative symporter YwcA Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene3527 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03528 S100141_03529 S100141_03529 xylB xylB 3269220 3270719 - Xylulokinase ATP-binding%3B Carbohydrate metabolism%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Xylose metabolism%3B Belongs to the FGGY kinase family%3B KEGG: sod:Sant_1620 xylulokinase gene gene3528 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03529 S100141_03530 S100141_03530 xylA xylA 3270719 3272065 - Xylose isomerase Carbohydrate metabolism%3B Cytoplasm%3B Isomerase%3B Magnesium%3B Metal-binding%3B Pentose shunt%3B Xylose metabolism%3B Belongs to the xylose isomerase family%3B KEGG: bli:BL03867 xylose isomerase gene gene3529 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03530 S100141_03531 S100141_03531 S100141_03531 3272257 3273420 + Xylose repressor Carbohydrate metabolism%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Xylose metabolism%3B Transcriptional repressor of xylose-utilizing enzymes. Belongs to the ROK (NagC/XylR) family gene gene3530 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03531 S100141_03532 S100141_03532 thiE thiE 3273661 3274335 - Thiamine phosphate synthase Magnesium%3B Metal-binding%3B Thiamine biosynthesis%3B Transferase%3B Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)%3B Belongs to the thiamine-phosphate synthase family%3B KEGG: bli:BL03866 thiamine-phosphate pyrophosphorylase gene gene3531 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03532 S100141_03533 S100141_03533 thiM thiM 3274337 3275146 - Hydroxyethylthiazole kinase ATP-binding%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Thiamine biosynthesis%3B Transferase%3B Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)%3B Belongs to the Thz kinase family%3B KEGG: bli:BL03865 hydroxyethylthiazole kinase gene gene3532 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03533 S100141_03534 S100141_03534 S100141_03534 3275143 3276060 - putative HTH-type transcriptional regulator YwbI DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH lysR-type DNA-binding domain gene gene3533 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03534 S100141_03535 S100141_03535 S100141_03535 3276181 3276450 - uncharacterized protein Coiled coil%3B overlaps another CDS with the same product name gene gene3534 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03535 S100141_03536 S100141_03536 S100141_03536 3276447 3276875 - uncharacterized protein Coiled coil%3B overlaps another CDS with the same product name gene gene3535 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03536 S100141_03537 S100141_03537 S100141_03537 3277350 3277736 + Holin-like protein CidA Cell membrane%3B Cytolysis%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell%2C the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment%2C CidA possibly oligomerizes within the bacterial cell membrane%2C creating lesions that disrupt the proton motive force%2C which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and/or regulating their activity by a possible change in the cell wall pH that results from loss of membrane potential%3B Belongs to the CidA/LrgA family. CidA subfamily gene gene3536 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03537 S100141_03538 S100141_03538 S100141_03538 3277718 3278401 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the YohK (E. coli)/YwbG (IPA-22R) (B. subtilis) family gene gene3537 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03538 S100141_03539 S100141_03539 S100141_03539 3278458 3278742 - hypothetical protein gene gene3538 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03539 S100141_03540 S100141_03540 S100141_03540 3278753 3280219 - Osmoregulated proline transporter OpuE Amino-acid transport%3B Cell membrane%3B Membrane%3B Stress response%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Catalyzes the uptake of extracellular proline under high-osmolarity growth conditions. Essential for the use of proline present in the environment as an osmoprotectant%3B Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene3539 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03540 S100141_03541 S100141_03541 rlmI rlmI 3280318 3281508 - 23S rRNA (cytosine(1962)-C(5))-methyltransferase Cytoplasm%3B Methyltransferase%3B RNA-binding%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B Belongs to the methyltransferase superfamily. RlmI family%3B Contains 1 PUA domain%3B KEGG: bli:BL03857 23S rRNA (cytosine1962-C5)-methyltransferase gene gene3540 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03541 S100141_03542 S100141_03542 S100141_03542 3281651 3282031 + Lactoylglutathione lyase Lyase%3B Belongs to the glyoxalase I family%3B KEGG: bli:BL03939 lactoylglutathione lyase gene gene3541 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03542 S100141_03543 S100141_03543 S100141_03543 3282062 3283009 - Phosphoglycerate dehydrogenase Cytoplasm%3B NAD%3B NADP%3B Oxidoreductase%3B Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate%2C respectively%3B Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily%3B KEGG: blh:BaLi_c40720 D-3-phosphoglycerate dehydrogenase gene gene3542 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03543 S100141_03544 S100141_03544 waaJ waaJ 3283148 3284011 - Lipopolysaccharide glucosyltransferase I Glycosyltransferase%3B Stress response%3B Transferase%3B Belongs to the glycosyltransferase 8 family%3B KEGG: stm:STM3717 UDP-glucose:(galactosyl)LPS alpha-1%2C2-glucosyltransferase gene gene3543 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03544 S100141_03545 S100141_03545 S100141_03545 3284133 3284303 - putative membrane protein YdzP Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3544 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03545 S100141_03546 S100141_03546 ydfH ydfH 3284807 3285970 + Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system YdfH/YdfI. May activate YdfI by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bsu:BSU05410 two-component system%2C NarL family%2C sensor histidine kinase YdfH gene gene3545 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03546 S100141_03547 S100141_03547 S100141_03547 3285963 3286601 + Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon Chemotaxis%3B Cytoplasm%3B Hydrolase%3B Phosphoprotein%3B Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene3546 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03547 S100141_03548 S100141_03548 S100141_03548 3286718 3288892 + Membrane protein YdfJ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family. MmpL subfamily gene gene3547 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03548 S100141_03549 S100141_03549 S100141_03549 3288989 3289729 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3548 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03549 S100141_03550 S100141_03550 S100141_03550 3289824 3291155 - Inner membrane transport protein RhmT Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily. Phthalate permease family gene gene3549 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03550 S100141_03551 S100141_03551 dgoD dgoD 3291217 3292365 - Galactonate dehydratase Lyase%3B Magnesium%3B Metal-binding%3B Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate%3B Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily%3B KEGG: bli:BL03851 galactonate dehydratase gene gene3550 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03551 S100141_03552 S100141_03552 S100141_03552 3292382 3293008 - 2-dehydro-3-deoxy-phosphogluconate aldolase Cytoplasm%3B Lyase%3B Multifunctional enzyme%3B Schiff base%3B Belongs to the KHG/KDPG aldolase family%3B KEGG: bli:BL03850 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase gene gene3551 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03552 S100141_03553 S100141_03553 S100141_03553 3293036 3293989 - 2-dehydro-3-deoxygluconokinase ATP-binding%3B Carbohydrate metabolism%3B Kinase%3B Nucleotide-binding%3B Plasmid%3B Transferase%3B Involved in the degradation of glucose via the semi- phosphorylative Entner-Doudoroff pathway. Catalyzes the phosphorylation of 2-keto-3-deoxygluconate (KDG) to produce 2- keto-3-deoxy-6-phosphogluconate (KDPG)%3B Belongs to the carbohydrate kinase pfkB family%3B KEGG: efe:EFER_3552 2-dehydro-3-deoxygluconokinase gene gene3552 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03553 S100141_03554 S100141_03554 S100141_03554 3294007 3294765 - putative HTH-type transcriptional regulator YagI DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH iclR-type DNA-binding domain%3B Contains 1 iclR-ED (iclR effector binding) domain gene gene3553 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03554 S100141_03555 S100141_03555 S100141_03555 3294995 3296344 + Aminopeptidase YwaD Aminopeptidase%3B Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Secreted%3B Signal%3B Zinc%3B Catalyzes the hydrolysis of a range of N-terminal amino acids%3B Belongs to the peptidase M28 family. M28B subfamily%3B KEGG: bcz:BCZK5056 aminopeptidase%3B Aminopeptidases gene gene3554 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03555 S100141_03556 S100141_03556 S100141_03556 3296568 3297929 - putative MFS-type transporter YwoD Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene3555 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03556 S100141_03557 S100141_03557 S100141_03557 3297930 3298142 - hypothetical protein gene gene3556 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03557 S100141_03558 S100141_03558 S100141_03558 3298601 3299260 - GTP diphosphokinase ATP-binding%3B GTP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Functions as a (p)ppGpp synthase. In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. activities in response to changes in nutritional abundance. YwaC has probably a minor role in stringent response%3B Belongs to the RelA/SpoT family%3B KEGG: bli:BL03845 putative GTP pyrophosphokinase gene gene3557 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03558 S100141_03559 S100141_03559 S100141_03559 3299351 3299512 - hypothetical protein gene gene3558 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03559 S100141_03560 S100141_03560 S100141_03560 3299801 3299950 + putative membrane protein YwzH Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3559 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03560 S100141_03561 S100141_03561 dltA dltA 3299965 3301473 + D-alanine--poly(phosphoribitol) ligase ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp%3B Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily%3B KEGG: bli:BL03934 D-alanine--poly(phosphoribitol) ligase subunit 1 gene gene3560 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03561 S100141_03562 S100141_03562 S100141_03562 3301470 3302627 + Protein DltB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Could be involved in the transport of activated D- alanine through the membrane. Belongs to the membrane-bound acyltransferase family gene gene3561 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03562 S100141_03563 S100141_03563 dltC dltC 3302643 3302879 + D-alanine--poly(phosphoribitol) ligase ATP-binding%3B Cell shape%3B Cell wall biogenesis/degradation%3B Ligase%3B Nucleotide-binding%3B Phosphopantetheine%3B Phosphoprotein%3B Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA%3B Contains 1 acyl carrier domain%3B KEGG: bli:BL03932 D-alanine--poly(phosphoribitol) ligase subunit 2 gene gene3562 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03563 S100141_03564 S100141_03564 S100141_03564 3302879 3304048 + Protein DltD Signal. gene gene3563 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03564 S100141_03565 S100141_03565 S100141_03565 3304220 3305311 + Branched-chain-amino-acid transaminase Amino-acid biosynthesis%3B Aminotransferase%3B Branched-chain amino acid biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Transaminates branched-chain amino acids and ketoglutarate%3B Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bli:BL03930 branched-chain amino acid aminotransferase gene gene3564 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03565 S100141_03566 S100141_03566 S100141_03566 3305544 3306806 + putative MFS-type transporter YvqJ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene3565 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03566 S100141_03567 S100141_03567 celF celF 3306908 3308236 - 6-phospho-beta-glucosidase Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Manganese%3B Metal-binding%3B NAD%3B Hydrolyzes phospho-beta-glucosides%3B Belongs to the glycosyl hydrolase 4 family%3B KEGG: bsu:BSU38560 6-phospho-beta-glucosidase gene gene3566 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03567 S100141_03568 S100141_03568 S100141_03568 3308236 3308496 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cytoplasm%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in lichenan transport. Contains 1 PTS EIIA type-3 domain%3B KEGG: cama:F384_22785 PTS system%2C cellobiose-specific IIA component gene gene3567 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03568 S100141_03569 S100141_03569 S100141_03569 3308581 3309933 - Cellobiose permease IIC component Cell membrane%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in cellobiose transport. Contains 1 PTS EIIC type-3 domain gene gene3568 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03569 S100141_03570 S100141_03570 S100141_03570 3309948 3310253 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cytoplasm%3B Kinase%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in cellobiose transport. Contains 1 PTS EIIB type-3 domain%3B KEGG: ebi:EbC_39840 PTS system%2C cellobiose-specific IIB component gene gene3569 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03570 S100141_03571 S100141_03571 S100141_03571 3310380 3312329 - putative licABCH operon regulator Activator%3B Kinase%3B Phosphoprotein%3B Repeat%3B RNA-binding%3B Transcription%3B Transcription regulation%3B Transferase%3B Positive regulator of the licABCH operon. Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains%3B Contains 1 PTS EIIA type-2 domain%3B Contains 1 PTS EIIB type-2 domain gene gene3570 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03571 S100141_03572 S100141_03572 S100141_03572 3312485 3312592 - hypothetical protein gene gene3571 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03572 S100141_03573 S100141_03573 S100141_03573 3312655 3313245 - DNA-3-methyladenine glycosylase II DNA damage%3B DNA repair%3B Hydrolase%3B Belongs to the DNA glycosylase MPG family%3B KEGG: bli:BL05369 DNA-3-methyladenine glycosylase gene gene3572 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03573 S100141_03574 S100141_03574 S100141_03574 3313452 3314123 + putative HTH-type transcriptional regulator in unstable DNA locus DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH gntR-type DNA-binding domain gene gene3573 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03574 S100141_03575 S100141_03575 S100141_03575 3314199 3315314 + Citrate (Si)-synthase Transferase%3B Tricarboxylic acid cycle%3B Belongs to the citrate synthase family%3B KEGG: bli:BL00561 citrate synthase gene gene3574 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03575 S100141_03576 S100141_03576 prpD prpD 3315350 3316789 + 2-methylcitrate dehydratase Lyase%3B Mitochondrion%3B Transit peptide%3B Component of the methylcitrate cycle that catalyzes the dehydration of 2-methylcitrate to 2-methyl-cis-aconitate. The methylcitrate cycle is a metabolic pathway for the consumption of propionic acid%3B Belongs to the PrpD family%3B KEGG: bli:BL00562 2-methylcitrate dehydratase gene gene3575 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03576 S100141_03577 S100141_03577 S100141_03577 3316802 3317719 + Carboxyvinyl-carboxyphosphonate phosphorylmutase Lyase%3B Magnesium%3B Metal-binding%3B Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R%2C3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate%3B Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family%3B KEGG: bli:BL00563 carboxyvinyl-carboxyphosphonate phosphorylmutase gene gene3576 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03577 S100141_03578 S100141_03578 S100141_03578 3317762 3318955 - putative chromate transport protein Cell membrane%3B Chromate resistance%3B Membrane%3B Plasmid%3B Stress response%3B Transmembrane%3B Transmembrane helix%3B Transport%3B May function in the active transport of chromate into the cell under sulfur-deficient conditions. Belongs to the chromate ion transporter (CHR) (TC 2. A. 51) family gene gene3577 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03578 S100141_03579 S100141_03579 S100141_03579 3318968 3319399 - hypothetical protein gene gene3578 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03579 S100141_03580 S100141_03580 S100141_03580 3319422 3321137 - putative ABC transporter ATP-binding protein YwjA ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene3579 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03580 S100141_03581 S100141_03581 S100141_03581 3321252 3321911 - Rhamnogalacturonan acetylesterase RhgT Hydrolase%3B May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls. This enzyme has a broad substrate specificity%2C and shows strong preference for glucose pentaacetate%2C beta-naphthylacetate%2C and p-nitrophenyl acetate (pNPA). Also active toward acetylated xylan%3B Belongs to the 'GDSL' lipolytic enzyme family gene gene3580 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03581 S100141_03582 S100141_03582 S100141_03582 3322224 3322808 + uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix%3B To B. subtilis YuaB gene gene3581 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03582 S100141_03583 S100141_03583 S100141_03583 3323036 3323509 + uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix%3B Required for complex colony architecture gene gene3582 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03583 S100141_03584 S100141_03584 S100141_03584 3323550 3324779 - Multidrug resistance protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Multidrug resistance pump that participates in a low energy shock adaptive response. Belongs to the major facilitator superfamily gene gene3583 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03584 S100141_03585 S100141_03585 S100141_03585 3324889 3325665 - putative transmembrane protein YxlG Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3584 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03585 S100141_03586 S100141_03586 S100141_03586 3325662 3326549 - Putative phosphonates utilization ATP-binding protein ATP-binding%3B Nucleotide-binding%3B Transport%3B Belongs to an operon involved in alkylphosphonate uptake and C-P lyase. Exact function not known. PhnK is not required for the ribophosphonate triphosphate (RPnTP) synthase reaction. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene3585 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03586 S100141_03587 S100141_03587 S100141_03587 3326549 3326761 - Negative regulatory protein YxlE Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Together with YxlD is important for negative regulation of sigma Y activity gene gene3586 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03587 S100141_03588 S100141_03588 S100141_03588 3326758 3326976 - Negative regulatory protein YxlD Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Together with YxlE%2C is important for negative regulation of sigma Y activity%2C being the major negative regulator gene gene3587 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03588 S100141_03589 S100141_03589 S100141_03589 3326977 3327300 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3588 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03589 S100141_03590 S100141_03590 S100141_03590 3327297 3327923 - ECF RNA polymerase sigma factor SigW DNA-binding%3B Sigma factor%3B Stress response%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma factors are held in an inactive form by a cognate anti-sigma factor (RsiW for this protein) until released by regulated membrane proteolysis. Sigma-W controls genes involved in transport processes and detoxification%3B Belongs to the sigma-70 factor family. ECF subfamily gene gene3589 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03590 S100141_03591 S100141_03591 S100141_03591 3327984 3329237 + putative MFS-type transporter YxlH Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily. TCR/Tet family gene gene3590 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03591 S100141_03592 S100141_03592 katE katE 3329281 3330879 - Catalase Cytoplasm%3B Heme%3B Hydrogen peroxide%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Peroxidase%3B Decomposes hydrogen peroxide into water and oxyge%3B serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family%3B KEGG: bli:BL00939 catalase gene gene3591 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03592 S100141_03593 S100141_03593 S100141_03593 3331065 3332522 + Catalase Cytoplasm%3B Heme%3B Hydrogen peroxide%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Peroxidase%3B Decomposes hydrogen peroxide into water and oxyge%3B serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family%3B KEGG: bli:BL00951 catalase gene gene3592 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03593 S100141_03594 S100141_03594 S100141_03594 3332640 3333056 + Peroxide operon regulator Cytoplasm%3B Disulfide bond%3B DNA-binding%3B Manganese%3B Metal-binding%3B Oxidation%3B Repressor%3B Transcription%3B Transcription regulation%3B Zinc%3B Hydrogen and organic peroxide sensor. Represses the expression of a regulon of peroxide-inducible genes such as katA%2C ahpC%2C ahpF%2C the heme biosynthesis operon (hemAXCDBL)%2C fur%2C perR%2C zosA and mrgA. Belongs to the Fur family gene gene3593 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03594 S100141_03595 S100141_03595 S100141_03595 3333063 3334016 + Protoporphyrin ferrochelatase Cytoplasm%3B Heme biosynthesis%3B Iron%3B Lyase%3B Metal-binding%3B Porphyrin biosynthesis%3B Catalyzes the ferrous insertion into protoporphyrin IX%3B Belongs to the ferrochelatase family%3B KEGG: bsu:BSU10130 ferrochelatase gene gene3594 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03595 S100141_03596 S100141_03596 S100141_03596 3334043 3334984 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3595 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03596 S100141_03597 S100141_03597 S100141_03597 3334990 3335892 - Ribose import ATP-binding protein RbsA ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Repeat%3B Sugar transport%3B Transport%3B Part of the ABC transporter complex RbsABCD involved in ribose import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Ribose importer (TC 3. A. 1. 2. 1) family%3B Contains 2 ABC transporter domains gene gene3596 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03597 S100141_03598 S100141_03598 S100141_03598 3335873 3336622 - hypothetical protein gene gene3597 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03598 S100141_03599 S100141_03599 S100141_03599 3336576 3337289 - hypothetical protein gene gene3598 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03599 S100141_03600 S100141_03600 S100141_03600 3337276 3337911 - Sulfate/thiosulfate import ATP-binding protein CysA ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Sulfate transport%3B Transport%3B Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3. A. 1. 6) family%3B Contains 1 ABC transporter domain gene gene3599 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03600 S100141_03601 S100141_03601 S100141_03601 3337914 3338201 - hypothetical protein gene gene3600 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03601 S100141_03602 S100141_03602 S100141_03602 3338201 3338440 - putative HTH-type transcriptional regulator DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene3601 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03602 S100141_03603 S100141_03603 S100141_03603 3338589 3338777 - hypothetical protein gene gene3602 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03603 S100141_03604 S100141_03604 S100141_03604 3338783 3340114 - hypothetical protein gene gene3603 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03604 S100141_03605 S100141_03605 S100141_03605 3340111 3342204 - Lacticin-481/lactococcin-DR transport/processing ATP-binding protein lcnDR3 ATP-binding%3B Bacteriocin transport%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Protease%3B Protein transport%3B Thiol protease%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably implicated in the export process of the lantibiotic lacticin-481/lactococcin-DR. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain%3B Contains 1 peptidase C39 domain gene gene3604 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03605 S100141_03606 S100141_03606 S100141_03606 3342276 3345386 - Lacticin 481/lactococcin biosynthesis protein lcnDR2 Antibiotic biosynthesis%3B Bacteriocin biosynthesis. gene gene3605 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03606 S100141_03607 S100141_03607 S100141_03607 3345437 3345655 - Lantibiotic lichenicidin VK21 A2 Antibiotic%3B Antimicrobial%3B Bacteriocin%3B Lantibiotic%3B Secreted%3B Thioether bond%3B Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes%2C initiated by the formation of aqueous transmembrane pores. When present individually%2C LchA2 exhibits activity towards B. subtilis L1 (IC(50)%3D30 uM)%2C Rhodococcus sp. SS2 (IC(50)%3D16. 6 uM)%2C M. luteus B1314 (IC(50)%3D2. 6 uM)%2C B. megaterium VKM41 (IC(50)%3D2 uM)%2C S. aureus 209p (IC(50)%3D20 uM)%2C B. pumilus 2001%2C B. globigii I%2C B. amyloliquefaciens I%2C M. smegmatis 1171 and M. phlei 1291. However%2C when combined with LchA1%2C it displays much stronger activty against B. subtilis L1 (IC(50)%3D0. 64 uM)%2C Rhodococcus sp. SS2 (IC(50)%3D0. 64 uM)%2C M. luteus B1314 (IC(50)%3D0. 09 uM)%2C B. megaterium VKM41 (IC(50)%3D0. 12 uM) and S. aureus 209p (IC(50)%3D0. 64 uM). The activity of the combined LchA1 and LchA2 peptides is strongest at a molar ratio of 1. Even when applied at 17-fold concentration of the highest IC(50) values for Gram-positive bacteria%2C neither the individual nor the combined peptides display activity against Gram-negative bacteria P. aeruginosa PAO1%2C P. putida I-97 or E. coli C600 gene gene3606 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03607 S100141_03608 S100141_03608 S100141_03608 3345793 3346017 + Lantibiotic lichenicidin Antibiotic%3B Antimicrobial%3B Bacteriocin%3B Cell wall%3B Lantibiotic%3B Secreted%3B Thioether bond%3B Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes%2C initiated by the formation of aqueous transmembrane pores. When present individually%2C LchA1 exhibits activity towards L. lactis HP. When combined with LchA2%2C it displays activity towards a broad spectrum of non-pathogenic and pathogenic Gram-positive bacteria including strains of L. monocytogenes%2C methicillin-resistant S. aureus%2C S. pneumoniae and strains of vancomycin-resistant enterococci%2C but not towards E. faecium L4001 and BM4147-1. Combined LchA1 and LchA2 peptides also inhibit Bacillus sp. HIL-Y85/54728%2C L. lactis DPC3417 and B. halodurans C-125%2C which produce lantibiotics themselves. Inactivated by proteinase K and pronase E%2C but not by trypsin and chymotrypsin gene gene3607 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03608 S100141_03609 S100141_03609 S100141_03609 3346079 3349237 + Lacticin 481/lactococcin biosynthesis protein lcnDR2 Antibiotic biosynthesis%3B Bacteriocin biosynthesis. gene gene3608 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03609 S100141_03610 S100141_03610 S100141_03610 3349528 3350553 + Pectate lyase Calcium%3B Carbohydrate metabolism%3B Cell wall biogenesis/degradation%3B Lyase%3B Metal-binding%3B Polysaccharide degradation%3B Repeat%3B Secreted%3B Signal%3B Cleaves unsaturated oligo-galacturonides from pectin. The major product is trigalacturonat%3B digalacturonate and tetragalacturonate are also produced. Activity on methylated pectins decreases with an increasing degree of methylation (By similarity)%3B Belongs to the polysaccharide lyase 1 family%3B Contains 4 PbH1 repeats%3B KEGG: blh:BaLi_c41260 pectate lyase gene gene3609 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03610 S100141_03611 S100141_03611 S100141_03611 3350590 3351441 - ADP-dependent NAD(P)H-hydrate dehydratase ATP-binding%3B Isomerase%3B Lyase%3B Metal-binding%3B Multifunctional enzyme%3B NAD%3B NADP%3B Nucleotide-binding%3B Potassium%3B Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP%2C which is converted to AMP. This allows the repair of both epimers of NAD(P)HX%2C a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)%3B In the N-terminal sectio%3B belongs to the NnrE/AIBP family%3B In the C-terminal sectio%3B belongs to the NnrD/CARKD family%3B Contains 1 YjeF C-terminal domain%3B Contains 1 YjeF N-terminal domain%3B KEGG: bli:BL00927 ADP-dependent NAD(P)H-hydrate dehydratase gene gene3610 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03611 S100141_03612 S100141_03612 S100141_03612 3351610 3353358 - ATP-binding/permease protein CydD ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system (By similarity)%3B Belongs to the ABC transporter superfamily. Cysteine exporter (TC 3. A. 1. 129. 1) family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene3611 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03612 S100141_03613 S100141_03613 S100141_03613 3353355 3355079 - ATP-binding/permease protein CydC ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system (By similarity)%3B Belongs to the ABC transporter superfamily. Cysteine exporter (TC 3. A. 1. 129. 1) family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene3612 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03613 S100141_03614 S100141_03614 S100141_03614 3355079 3356095 - Cytochrome bd ubiquinol oxidase subunit Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the cytochrome ubiquinol oxidase subunit 2 family%3B KEGG: bli:BL00924 cytochrome d ubiquinol oxidase subunit II%3B With oxygen as acceptor%3B overlaps another CDS with the same product name gene gene3613 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03614 S100141_03615 S100141_03615 S100141_03615 3356082 3357488 - Cytochrome bd ubiquinol oxidase subunit Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the cytochrome ubiquinol oxidase subunit 1 family%3B KEGG: gbm:Gbem_2016 cytochrome d ubiquinol oxidase subunit I%3B With oxygen as acceptor%3B overlaps another CDS with the same product name gene gene3614 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03615 S100141_03616 S100141_03616 S100141_03616 3358287 3359075 + putative transporter YwcJ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the FNT transporter (TC 2. A. 44) family gene gene3615 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03616 S100141_03617 S100141_03617 S100141_03617 3359220 3359549 + hypothetical protein gene gene3616 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03617 S100141_03618 S100141_03618 S100141_03618 3359567 3360898 - Malate dehydrogenase (oxaloacetate-decarboxylating) Metal-binding%3B NAD%3B Oxidoreductase%3B Belongs to the malic enzymes family%3B Contains 1 ACT domain%3B KEGG: bli:BL00922 malate dehydrogenase (oxaloacetate-decarboxylating) gene gene3617 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03618 S100141_03619 S100141_03619 S100141_03619 3360933 3362330 - Malate-2H(+)/Na(+)-lactate antiporter Antiport%3B Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Couples proton uptake and Na(+) efflux to the substrate- product malate/lactate antiport%2C in an electroneutral malate- 2H(+)/Na(+)-lactate exchange. Plays a role in supporting growth to high density on malate at reduced protonmotive force. Belongs to the NhaC Na(+)/H(+) (TC 2. A. 35) antiporter family gene gene3618 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03619 S100141_03620 S100141_03620 aspA aspA 3362573 3364000 - Aspartate ammonia-lyase Lyase%3B Belongs to the class-II fumarase/aspartase family. Aspartase subfamily%3B KEGG: bli:BL05376 aspartate ammonia-lyase gene gene3619 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03620 S100141_03621 S100141_03621 S100141_03621 3364021 3365010 - Asparaginase Alternative initiation%3B Cytoplasm%3B Hydrolase%3B Belongs to the asparaginase 1 family%3B Contains 1 asparaginase/glutaminase domain%3B KEGG: bsu:BSU23580 L-asparaginase gene gene3620 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03621 S100141_03622 S100141_03622 S100141_03622 3365226 3365573 + HTH-type transcriptional regulator AnsR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcriptional repressor for the ans operon coding for L-asparaginase and L-aspartase. NH4(+) may influence this repression. Contains 1 HTH cro/C1-type DNA-binding domain gene gene3621 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03622 S100141_03623 S100141_03623 S100141_03623 3365654 3366700 - 6-phosphogluconolactonase Carbohydrate metabolism%3B Glucose metabolism%3B Hydrolase%3B Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate%3B Belongs to the cycloisomerase 2 family%3B KEGG: bli:BL02413 6-phosphogluconolactonase gene gene3622 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03623 S100141_03624 S100141_03624 S100141_03624 3366897 3367586 + Response regulator ArlR Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system ArlS/ArlR%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3623 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03624 S100141_03625 S100141_03625 yxdK yxdK 3367583 3368563 + Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Probable member of the two-component regulatory system YxdK/YxdJ. May activate YxdJ in response to the antibacterial protein LL-37%3B Contains 1 histidine kinase domain%3B KEGG: bli:BL02955 two-component system%2C OmpR family%2C sensor histidine kinase YxdK gene gene3624 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03625 S100141_03626 S100141_03626 S100141_03626 3368846 3369622 + Methionine import ATP-binding protein MetN Amino-acid transport%3B ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Methionine importer (TC 3. A. 1. 24) family%3B Contains 1 ABC transporter domain gene gene3625 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03626 S100141_03627 S100141_03627 S100141_03627 3369597 3371474 + ABC transporter permease protein YxdM Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex YxdLM which could be involved in peptide resistance. Belongs to the ABC-4 integral membrane protein family gene gene3626 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03627 S100141_03628 S100141_03628 S100141_03628 3371481 3371831 + uncharacterized protein Signal. gene gene3627 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03628 S100141_03629 S100141_03629 S100141_03629 3371947 3372117 + hypothetical protein gene gene3628 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03629 S100141_03630 S100141_03630 S100141_03630 3372433 3372684 + hypothetical protein gene gene3629 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03630 S100141_03631 S100141_03631 pgaB pgaB 3372717 3373556 - Putative polysaccharide deacetylase YxkH Cell membrane%3B Hydrolase%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Belongs to the polysaccharide deacetylase family%3B KEGG: bbe:BBR47_54040 biofilm PGA synthesis lipoprotein PgaB%3B Hydrolases gene gene3630 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03631 S100141_03632 S100141_03632 S100141_03632 3373617 3374513 - HTH-type transcriptional regulatory protein GabR Activator%3B Aminotransferase%3B DNA-binding%3B Pyridoxal phosphate%3B Repressor%3B Transcription%3B Transcription regulation%3B Transferase%3B Activates the transcription of the gabTD operon. Is also a repressor of its own expression%2C both in the presence and absence of GABA. Binds specifically to the DNA region overlapping the -35 region of the gabT promoter and the -10 and +1 regions of the gabR promoter. Principally regulates the utilization of gamma- aminobutyrate%3B In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene3631 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03632 S100141_03633 S100141_03633 bcsA bcsA 3374654 3376912 - Cellulose synthase (UDP-forming) Cell inner membrane%3B Cell membrane%3B Cellulose biosynthesis%3B Glycosyltransferase%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B In the N-terminal sectio%3B belongs to the glycosyltransferase 2 family%3B In the C-terminal sectio%3B belongs to the AcsB/BcsB family%3B Contains 1 PilZ domain%3B KEGG: bpu:BPUM_3398 cellulose synthase (UDP-forming) gene gene3632 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03633 S100141_03634 S100141_03634 S100141_03634 3377044 3377376 + hypothetical protein gene gene3633 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03634 S100141_03635 S100141_03635 S100141_03635 3377346 3378206 + putative transposase-like protein DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene3634 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03635 S100141_03636 S100141_03636 S100141_03636 3378789 3380141 + Citrate/malate transporter Cell membrane%3B Citrate utilization%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Proton motive force-driven secondary transporter that catalyzes the uptake of both citrate and malate. Appears to be an electroneutral proton-solute symporte%3B the number of protons transported is equal to the valence of the transported anions. Is strictly stereoselective%2C translocating only the (S)-enantiomer of malate. Belongs to the sodium:citrate (SCF) symporter family gene gene3635 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03636 S100141_03637 S100141_03637 S100141_03637 3380188 3381048 - Glycerophosphodiester phosphodiesterase Calcium%3B Glycerol metabolism%3B Hydrolase%3B Metal-binding%3B Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to sn-glycerol 3-phosphate (G3P) and the corresponding alcohols%3B Belongs to the glycerophosphoryl diester phosphodiesterase family%3B Contains 1 GP-PDE domain%3B KEGG: bli:BL02963 glycerophosphoryl diester phosphodiesterase gene gene3636 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03637 S100141_03638 S100141_03638 S100141_03638 3381189 3381458 - uncharacterized protein Signal. gene gene3637 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03638 S100141_03639 S100141_03639 S100141_03639 3381600 3382259 - hypothetical protein gene gene3638 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03639 S100141_03640 S100141_03640 S100141_03640 3382379 3384298 - Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase Cell membrane%3B Cell wall biogenesis/degradation%3B Manganese%3B Membrane%3B Metal-binding%3B Secreted%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate%2C a reaction that presumably uses phosphatidylglycerol (PG) as substrate%3B Belongs to the LTA synthase family%3B KEGG: bli:BL02415 lipoteichoic acid synthase gene gene3639 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03640 S100141_03641 S100141_03641 S100141_03641 3384570 3385127 - uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix%3B To B. subtilis YfjD gene gene3640 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03641 S100141_03642 S100141_03642 S100141_03642 3385300 3386220 - UPF0750 membrane protein YxkD Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0750 family gene gene3641 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03642 S100141_03643 S100141_03643 S100141_03643 3386498 3386938 + Arginine regulator Arginine metabolism%3B Cytoplasm%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Regulates the transcription of the arc operon%2C involved in arginine catabolism%3B Belongs to the ArgR family gene gene3642 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03643 S100141_03644 S100141_03644 arcA arcA 3387206 3388441 + Arginine deiminase Arginine metabolism%3B Cytoplasm%3B Hydrolase%3B Belongs to the arginine deiminase family%3B KEGG: bli:BL01912 arginine deiminase gene gene3643 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03644 S100141_03645 S100141_03645 S100141_03645 3388470 3389477 + Ornithine carbamoyltransferase Arginine metabolism%3B Cytoplasm%3B Transferase%3B Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline%3B Belongs to the ATCase/OTCase family%3B KEGG: bli:BL01914 ornithine carbamoyltransferase gene gene3644 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03645 S100141_03646 S100141_03646 S100141_03646 3389531 3390937 + Putative amino-acid transporter Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Could be an amino acid transporter. Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene3645 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03646 S100141_03647 S100141_03647 S100141_03647 3390959 3391909 + Carbamate kinase Arginine metabolism%3B ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the carbamate kinase family%3B KEGG: bli:BL01916 carbamate kinase gene gene3646 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03647 S100141_03648 S100141_03648 S100141_03648 3392019 3392696 + CRP-like cAMP-activated global transcriptional regulator Activator%3B cAMP%3B cAMP-binding%3B DNA-binding%3B Kinase%3B Nucleotide-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Transferase%3B Global transcriptional regulator that complexes with cAMP and binds to specific DNA promoter sites%2C causing DNA- bending%2C to regulate transcription. cAMP improves binding to specific DNA sequences%2C probably by altering protein conformation. Involved in the regulation of gntP and gntK genes%2C which are involved in gluconate metabolism (PubMed:16385030). May form dimers which bind to the aceB promoter region in the presence of cAMP and repress the glyoxylate bypass genes (PubMed:15150232). It could be a positive regulator of rpf2 gene expression during growth on acetate as the sole carbon source%2C however because the cytosolic cAMP level is elevated in the presence of glucose and low upon growth on acetate%2C it is conceivable that it is unable to function as an activator under acetate conditions (PubMed:18355281)%3B Contains 1 cyclic nucleotide-binding domain%3B Contains 1 HTH crp-type DNA-binding domain gene gene3647 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03648 S100141_03649 S100141_03649 bglB bglB 3392748 3394184 - Beta-glucosidase Chloroplast%3B Disulfide bond%3B Glycosidase%3B Hydrolase%3B Plant defense%3B Plastid%3B Transit peptide%3B Beta-glucosidase acting as a preformed defense system. Hydrolyzes the bisdesmosides avenacosides A and B to 26-desgluco- avenacosides exhibiting fungicidal activity. Can use beta-fucoside > beta-glucoside > beta-galactoside > beta-xyloside as substrates%2C but not alpha-glycosides%2C beta-thioglucosides and disaccharides%3B Belongs to the glycosyl hydrolase 1 family%3B KEGG: bli:BL01920 beta-glucosidase gene gene3648 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03649 S100141_03650 S100141_03650 S100141_03650 3394208 3395527 - Oligo-beta-mannoside permease IIC component Cell membrane%3B Membrane%3B Phosphotransferase system%3B Polysaccharide transport%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in the transport of oligo- glucomannans such as cellobiose or mannobiose (Probable)%3B Contains 1 PTS EIIC type-3 domain gene gene3649 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03650 S100141_03651 S100141_03651 S100141_03651 3395685 3397076 - hypothetical protein gene gene3650 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03651 S100141_03652 S100141_03652 S100141_03652 3397046 3397594 - RNA polymerase sigma factor SigV Activator%3B DNA-binding%3B Sigma factor%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin%2C paraquat and tellurite%3B Belongs to the sigma-70 factor family. ECF subfamily gene gene3651 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03652 S100141_03653 S100141_03653 S100141_03653 3397704 3398333 - [Formate-C-acetyltransferase]-activating enzyme 4Fe-4S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase%3B S-adenosyl-L-methionine%3B Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical%2C using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. Belongs to the organic radical-activating enzymes family%3B KEGG: cbo:CBO1002 anaerobic ribonucleoside-triphosphate reductase activating protein gene gene3652 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03653 S100141_03654 S100141_03654 S100141_03654 3398333 3398998 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3653 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03654 S100141_03655 S100141_03655 S100141_03655 3398991 3399209 - hypothetical protein gene gene3654 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03655 S100141_03656 S100141_03656 S100141_03656 3399221 3399664 - hypothetical protein gene gene3655 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03656 S100141_03657 S100141_03657 S100141_03657 3399681 3401345 - Vesicle-fusing ATPase ATP-binding%3B Chloroplast%3B Nucleotide-binding%3B Plastid%3B Belongs to the AAA ATPase family. Highly divergent%3B KEGG: pca:Pcar_0681 vesicle-fusing ATPase gene gene3656 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03657 S100141_03658 S100141_03658 pepT pepT 3401485 3402717 + Tripeptide aminopeptidase Aminopeptidase%3B Cytoplasm%3B Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Zinc%3B Cleaves the N-terminal amino acid of tripeptides%3B Belongs to the peptidase M20B family%3B KEGG: smaf:D781_1854 tripeptide aminopeptidase gene gene3657 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03658 S100141_03659 S100141_03659 S100141_03659 3402876 3404354 - Beta-fructofuranosidase Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Secreted%3B Signal%3B Exo-fructosidase that can hydrolyze both levan and inulin%2C leading to the production of free fructose. Is also able to hydrolyze sucrose and to a small extent raffinose%2C but not melezitose%2C stachylose%2C cellobiose%2C maltose%2C and lactose%3B Belongs to the glycosyl hydrolase 32 family%3B KEGG: bli:BL01929 beta-fructofuranosidase gene gene3658 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03659 S100141_03660 S100141_03660 S100141_03660 3404369 3405604 - Sucrose transport protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Sugar transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Proton symport transport system. Has an essential role in sucrose metabolism. Belongs to the LacY/RafB permease family gene gene3659 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03660 S100141_03661 S100141_03661 S100141_03661 3406043 3407017 + Catabolite control protein DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcriptional regulator involved in catabolite repression of several operons. Contains 1 HTH lacI-type DNA-binding domain gene gene3660 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03661 S100141_03662 S100141_03662 S100141_03662 3407206 3407730 + hypothetical protein gene gene3661 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03662 S100141_03663 S100141_03663 S100141_03663 3407829 3408512 - uncharacterized protein Signal. gene gene3662 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03663 S100141_03664 S100141_03664 S100141_03664 3408539 3408700 - hypothetical protein gene gene3663 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03664 S100141_03665 S100141_03665 S100141_03665 3409015 3410145 + 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase To B. subtilis YxjH%3B KEGG: tmn:UCRPA7_3279 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase gene gene3664 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03665 S100141_03666 S100141_03666 S100141_03666 3410284 3412518 + Putative mannosyltransferase YkcB Cell membrane%3B Glycosyltransferase%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Belongs to the glycosyltransferase 39 family gene gene3665 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03666 S100141_03667 S100141_03667 S100141_03667 3412518 3413516 + Dolichyl-phosphate beta-D-mannosyltransferase Cell membrane%3B Glycosyltransferase%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Belongs to the glycosyltransferase 2 family. GtrB subfamily%3B KEGG: bld:BLi04189 dolichol-phosphate mannosyltransferase gene gene3666 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03667 S100141_03668 S100141_03668 S100141_03668 3413541 3414536 + UDP-glucose 4-epimerase Carbohydrate metabolism%3B Galactose metabolism%3B Isomerase%3B NAD%3B Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD (By similarity)%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: sbg:SBG_1909 UDP-glucose 4-epimerase gene gene3667 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03668 S100141_03669 S100141_03669 S100141_03669 3414741 3415880 - hypothetical protein gene gene3668 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03669 S100141_03670 S100141_03670 S100141_03670 3415891 3416667 - hypothetical protein gene gene3669 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03670 S100141_03671 S100141_03671 S100141_03671 3416658 3417320 - hypothetical protein gene gene3670 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03671 S100141_03672 S100141_03672 S100141_03672 3417339 3417977 - hypothetical protein gene gene3671 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03672 S100141_03673 S100141_03673 S100141_03673 3417980 3418276 - hypothetical protein gene gene3672 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03673 S100141_03674 S100141_03674 S100141_03674 3419034 3420227 + Pyrimidine nucleoside transport protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the concentrative nucleoside transporter (CNT) (TC 2. A. 41) family gene gene3673 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03674 S100141_03675 S100141_03675 S100141_03675 3420273 3421733 - Catalase Cell wall%3B Glycoprotein%3B Heme%3B Hydrogen peroxide%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Peroxidase%3B Secreted%3B Thioether bond%3B Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide%3B Belongs to the catalase family%3B KEGG: sml:Smlt3583 catalase gene gene3674 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03675 S100141_03676 S100141_03676 S100141_03676 3421737 3422354 - Catalase Heme%3B Hydrogen peroxide%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Peroxidase%3B Sporulation%3B Decomposes hydrogen peroxide into water and oxyge%3B serves to protect cells from the toxic effects of hydrogen peroxide. Involved in sporulation. Belongs to the catalase family. HPII subfamily%3B KEGG: blh:BaLi_c41890 catalase gene gene3675 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03676 S100141_03677 S100141_03677 S100141_03677 3422489 3422965 - hypothetical protein gene gene3676 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03677 S100141_03678 S100141_03678 S100141_03678 3423109 3424527 - 6-phospho-beta-glucosidase Carbohydrate metabolism%3B Cellulose degradation%3B Glycosidase%3B Hydrolase%3B Polysaccharide degradation%3B BglA is intracellular and cleaves cellobiose probably through inorganic phosphate mediated hydrolysis. Belongs to the glycosyl hydrolase 1 family%3B KEGG: bli:BL01946 6-phospho-beta-glucosidase gene gene3677 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03678 S100141_03679 S100141_03679 bglF bglF 3424517 3426376 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Kinase%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in beta-glucoside transport (By similarity)%3B Contains 1 PTS EIIA type-1 domain%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bli:BL01947 PTS system%2C beta-glucosides-specific IIA component gene gene3678 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03679 S100141_03680 S100141_03680 S100141_03680 3426687 3427520 - Beta-glucoside operon antiterminator Activator%3B Phosphoprotein%3B Repeat%3B RNA-binding%3B Transcription%3B Transcription regulation%3B Mediates the positive regulation of the beta-glucoside (arb) operon by functioning as a transcriptional antiterminator. This is an RNA-binding protein that recognizes a specific sequence located just upstream of two termination sites within the operon (By similarity)%3B Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains gene gene3679 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03680 S100141_03681 S100141_03681 S100141_03681 3427715 3428449 - Putative HMP/thiamine permease protein YkoC Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Probably responsible for the translocation of the substrate across the membrane (Probable)%3B Belongs to the CbiQ family gene gene3680 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03681 S100141_03682 S100141_03682 S100141_03682 3428446 3430038 - Putative ABC transporter ATP-binding protein ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Repeat%3B Transport%3B Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 2 ABC transporter domains%3B KEGG: bli:BL02650 energy-coupling factor transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene3681 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03682 S100141_03683 S100141_03683 S100141_03683 3430013 3430612 - Putative HMP/thiamine permease protein YkoE Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Probably responsible for the translocation of the substrate across the membrane (Probable) gene gene3682 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03683 S100141_03684 S100141_03684 S100141_03684 3430609 3431295 - Aminopyrimidine aminohydrolase Hydrolase%3B Thiamine biosynthesis%3B Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds%2C a reaction that is part of a thiamine salvage pathway. Thus%2C catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP). Is also able to catalyze the hydrolytic cleavage of thiamin%3B however%2C this thiaminase activity may not be physiologically relevant. Therefore%2C is probably involved in the regeneration of the thiamine pyrimidine from thiamine degraded products present in the environment%2C rather than in thiamine degradation%3B Belongs to the TenA family%3B KEGG: bli:BL02647 thiaminase (transcriptional activator TenA) gene gene3683 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03684 S100141_03685 S100141_03685 S100141_03685 3431714 3431872 + hypothetical protein gene gene3684 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03685 S100141_03686 S100141_03686 aceA aceA 3431924 3433195 - Isocitrate lyase Glyoxylate bypass%3B Lyase%3B Magnesium%3B Metal-binding%3B Tricarboxylic acid cycle%3B Involved in the persistence and virulence of Mycobacterium. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate%2C a key step of the glyoxylate cycle%2C which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates%3B Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family%3B KEGG: bli:BL02646 isocitrate lyase gene gene3685 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03686 S100141_03687 S100141_03687 aceB aceB 3433210 3434799 - Malate synthase Glyoxylate bypass%3B Glyoxysome%3B Peroxisome%3B Transferase%3B Tricarboxylic acid cycle%3B Belongs to the malate synthase family%3B KEGG: bli:BL02644 malate synthase gene gene3686 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03687 S100141_03688 S100141_03688 S100141_03688 3434842 3434979 - hypothetical protein gene gene3687 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03688 S100141_03689 S100141_03689 arnT arnT 3435184 3437265 + Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase Cell membrane%3B Glycosyltransferase%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Belongs to the glycosyltransferase 39 family%3B KEGG: amo:Anamo_1886 4-amino-4-deoxy-L-arabinose transferase gene gene3688 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03689 S100141_03690 S100141_03690 S100141_03690 3437418 3439358 - Bacitracin export permease protein BceB Antibiotic resistance%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex BceAB (TC 3. A. 1. 123. 5) involved in bacitracin export. Belongs to the ABC-4 integral membrane protein family gene gene3689 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03690 S100141_03691 S100141_03691 msbA msbA 3439348 3440109 - Bacitracin export ATP-binding protein BceA Antibiotic resistance%3B ATP-binding%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex BceAB (TC 3. A. 1. 123. 5) involved in bacitracin export. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: hpo:HMPREF4655_20610 ATP-binding cassette%2C subfamily B%2C bacterial MsbA%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene3690 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03691 S100141_03692 S100141_03692 bceS bceS 3440210 3441214 - Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system BceS/BceR involved in the regulation of bacitracin resistance. Activates BceR in response to extracellular bacitracin%3B Contains 1 histidine kinase domain%3B KEGG: bss:BSUW23_14730 two-component system%2C OmpR family%2C bacitracin resistance sensor histidine kinase BceS gene gene3691 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03692 S100141_03693 S100141_03693 S100141_03693 3441220 3441906 - Sensory transduction protein BceR Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system BceS/BceR involved in the regulation of bacitracin resistance. When activated by BceS%2C binds to the upstream region of the bceAB promoter and up-regulates the expression of these two genes (By similarity)%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3692 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03693 S100141_03694 S100141_03694 S100141_03694 3442017 3443426 - 6-phospho-beta-glucosidase Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P)%2C phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. BglA and BglH are the major proteins contributing to hydrolysis of MUG-P by extracts of late-exponential-phase or stationary-phase B. subtilis cells%3B Belongs to the glycosyl hydrolase 1 family%3B KEGG: bli:BL00212 6-phospho-beta-glucosidase gene gene3693 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03694 S100141_03695 S100141_03695 S100141_03695 3443467 3445311 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Kinase%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in beta-glucoside transport (By similarity)%3B Contains 1 PTS EIIA type-1 domain%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bsu:BSU39270 PTS system%2C beta-glucosides-specific IIA component gene gene3694 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03695 S100141_03696 S100141_03696 S100141_03696 3445640 3446182 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene3695 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03696 S100141_03697 S100141_03697 S100141_03697 3446201 3447190 - Choloylglycine hydrolase Hydrolase%3B Belongs to the peptidase C59 family%3B KEGG: bli:BL00216 choloylglycine hydrolase gene gene3696 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03697 S100141_03698 S100141_03698 S100141_03698 3447318 3448151 - hypothetical protein gene gene3697 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03698 S100141_03699 S100141_03699 S100141_03699 3448173 3449159 - hypothetical protein gene gene3698 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03699 S100141_03700 S100141_03700 S100141_03700 3449374 3450489 - Arabinan endo-1%2C5-alpha-L-arabinosidase Calcium%3B Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Metal-binding%3B Secreted%3B Signal%3B Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the internal cleavage of alpha-(1->5)-L-arabinofuranosyl residues of the alpha-1%2C5-L-arabinan to produce arabino- oligosaccharides and L-arabinose. It is also active toward linear branched sugar beet arabinan%2C and pectin from apple%3B Belongs to the glycosyl hydrolase 43 family%3B KEGG: sde:Sde_2809 arabinan endo-1%2C5-alpha-L-arabinosidase gene gene3699 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03700 S100141_03701 S100141_03701 S100141_03701 3450499 3451101 - hypothetical protein gene gene3700 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03701 S100141_03702 S100141_03702 S100141_03702 3451120 3451899 - hypothetical protein gene gene3701 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03702 S100141_03703 S100141_03703 S100141_03703 3451914 3453506 - Ribonuclease YxiD Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene3702 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03703 S100141_03704 S100141_03704 S100141_03704 3453524 3453793 - hypothetical protein gene gene3703 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03704 S100141_03705 S100141_03705 S100141_03705 3453803 3454195 - hypothetical protein gene gene3704 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03705 S100141_03706 S100141_03706 S100141_03706 3454524 3455825 - Pyrimidine-nucleoside phosphorylase Glycosyltransferase%3B Transferase%3B The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources%2C or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family%3B KEGG: bli:BL00227 pyrimidine-nucleoside phosphorylase gene gene3705 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03706 S100141_03707 S100141_03707 S100141_03707 3455856 3457037 - Pyrimidine nucleoside transport protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the concentrative nucleoside transporter (CNT) (TC 2. A. 41) family gene gene3706 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03707 S100141_03708 S100141_03708 S100141_03708 3457119 3457790 - Deoxyribose-phosphate aldolase Cytoplasm%3B Lyase%3B Schiff base%3B Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate%3B Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily%3B KEGG: bsu:BSU39420 deoxyribose-phosphate aldolase gene gene3707 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03708 S100141_03709 S100141_03709 S100141_03709 3457916 3458854 - Deoxyribonucleoside regulator DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Negative regulator of the dra-nupC-pdp operon. DeoR binds cooperatively to the operator DNA%2C which consists of a palindrome and a direct repeat sequence located 3' to the palindrome. Belongs to the SorC transcriptional regulatory family gene gene3708 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03709 S100141_03710 S100141_03710 S100141_03710 3458890 3459324 - hypothetical protein gene gene3709 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03710 S100141_03711 S100141_03711 S100141_03711 3459724 3460662 + Putative lipoprotein YdaJ Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal. gene gene3710 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03711 S100141_03712 S100141_03712 S100141_03712 3460673 3461494 + Diguanylate cyclase Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Contains 1 GGDEF domain%3B KEGG: bli:BL05221 diguanylate cyclase gene gene3711 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03712 S100141_03713 S100141_03713 S100141_03713 3461484 3462479 + uncharacterized protein Cell membrane%3B Membrane%3B Signal%3B Transmembrane%3B Transmembrane helix. gene gene3712 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03713 S100141_03714 S100141_03714 S100141_03714 3462499 3463206 + uncharacterized protein Cell membrane%3B Membrane%3B Signal%3B Transmembrane%3B Transmembrane helix. gene gene3713 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03714 S100141_03715 S100141_03715 mgdA mgdA 3463199 3464461 + 1%2C2-diacylglycerol 3-glucosyltransferase Glycosyltransferase%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Belongs to the glycosyltransferase 2 family%3B KEGG: synp:Syn7502_03368 1%2C2-diacylglycerol 3-beta-glucosyltransferase gene gene3714 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03715 S100141_03716 S100141_03716 S100141_03716 3464458 3466593 + uncharacterized protein Cell membrane%3B Membrane%3B Signal%3B Transmembrane%3B Transmembrane helix. gene gene3715 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03716 S100141_03717 S100141_03717 avtA avtA 3466624 3467880 - Valine--pyruvate transaminase Aminotransferase%3B Cytoplasm%3B Pyridoxal phosphate%3B Transferase%3B Involved in the biosynthesis of alanine%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bli:BL00232 valine--pyruvate aminotransferase gene gene3716 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03717 S100141_03718 S100141_03718 S100141_03718 3467873 3469147 - hypothetical protein gene gene3717 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03718 S100141_03719 S100141_03719 S100141_03719 3469144 3469710 - hypothetical protein gene gene3718 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03719 S100141_03720 S100141_03720 S100141_03720 3469712 3470989 - Carnosine synthase Amino-acid biosynthesis%3B Arginine biosynthesis%3B Cytoplasm%3B Lyase%3B Plasmid%3B In the C-terminal sectio%3B belongs to the lyase 1 family. Argininosuccinate lyase subfamily%3B Contains 1 ATP-grasp domain%3B KEGG: cme:CYME_CMF080C carnosine synthase gene gene3719 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03720 S100141_03721 S100141_03721 S100141_03721 3470946 3471884 - putative transporter Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene3720 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03721 S100141_03722 S100141_03722 S100141_03722 3472095 3472973 - Fructose-bisphosphate aldolase Lyase%3B Metal-binding%3B Phosphoprotein%3B Zinc%3B Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)%3B Belongs to the class II fructose-bisphosphate aldolase family. IolJ subfamily%3B KEGG: bge:BC1002_3213 fructose-bisphosphate aldolase%2C class II gene gene3721 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03722 S100141_03723 S100141_03723 iolI iolI 3472995 3473831 - 2-keto-myo-inositol isomerase Isomerase%3B Metal-binding%3B Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI%2C inosose or 2%2C4%2C6/3%2C5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2%2C3%2C5/4%2C6- pentahydroxycyclohexanone)%3B Belongs to the IolI family%3B KEGG: bsu:BSU39680 2-keto-myo-inositol isomerase gene gene3722 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03723 S100141_03724 S100141_03724 S100141_03724 3473901 3474767 - Protein IolH gene gene3723 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03724 S100141_03725 S100141_03725 S100141_03725 3474791 3475825 - Inositol 2-dehydrogenase NAD%3B Oxidoreductase%3B Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose)%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: eta:ETA_32880 myo-inositol 2-dehydrogenase / D-chiro-inositol 1-dehydrogenase gene gene3724 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03725 S100141_03726 S100141_03726 S100141_03726 3475850 3477154 - Minor myo-inositol transporter IolF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Minor myo-inositol uptake transporter%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene3725 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03726 S100141_03727 S100141_03727 iolE iolE 3477167 3478069 - Myo-inosose-2 dehydratase Cobalt%3B Lyase%3B Manganese%3B Catalyzes the dehydration of inosose (2-keto-myo- inositol%2C 2KMI or 2%2C4%2C6/3%2C5-pentahydroxycyclohexanone) to 3D- (3%2C5/4)-trihydroxycyclohexane-1%2C2-dione (D-2%2C3-diketo-4-deoxy-epi- inositol)%3B Belongs to the IolE/MocC family%3B KEGG: bli:BL00242 inosose dehydratase gene gene3726 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03727 S100141_03728 S100141_03728 iolD iolD 3478083 3479996 - 3D-(3%2C5/4)-trihydroxycyclohexane-1%2C2-dione acylhydrolase (decyclizing) Hydrolase%3B Magnesium%3B Metal-binding%3B NAD%3B Thiamine pyrophosphate%3B Involved in the cleavage of the C1-C2 bond of 3D- (3%2C5/4)-trihydroxycyclohexane-1%2C2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)%3B Belongs to the TPP enzyme family%3B KEGG: bsu:BSU39730 3D-(3%2C5/4)-trihydroxycyclohexane-1%2C2-dione acylhydrolase (decyclizing) gene gene3727 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03728 S100141_03729 S100141_03729 iolC iolC 3480028 3481005 - 5-dehydro-2-deoxygluconokinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)%3B Belongs to the carbohydrate kinase PfkB family%3B KEGG: bsu:BSU39740 5-dehydro-2-deoxygluconokinase gene gene3728 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03729 S100141_03730 S100141_03730 iolB iolB 3481033 3481848 - 5-deoxy-glucuronate isomerase Isomerase%3B Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)%3B Belongs to the isomerase IolB family%3B KEGG: bli:BL00245 5-deoxy-glucuronate isomerase gene gene3729 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03730 S100141_03731 S100141_03731 doeC doeC 3481923 3483386 - Methylmalonate semialdehyde dehydrogenase (acylating) NAD%3B Oxidoreductase%3B Converts malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA%2C respectively%3B Belongs to the aldehyde dehydrogenase family. IolA subfamily%3B KEGG: vej:VEJY3_17211 aspartate-semialdehyde dehydrogenase%3B With NAD(+) or NADP(+) as acceptor gene gene3730 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03731 S100141_03732 S100141_03732 S100141_03732 3483857 3484621 + HTH-type transcriptional regulator IolR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Iol operon repressor. Contains 1 HTH deoR-type DNA-binding domain gene gene3731 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03732 S100141_03733 S100141_03733 iolS iolS 3484705 3485640 + Protein IolS NADP%3B Oxidoreductase%3B Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily%3B KEGG: bli:BL00183 myo-inositol catabolism protein IolS%3B With NAD(+) or NADP(+) as acceptor gene gene3732 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03733 S100141_03734 S100141_03734 S100141_03734 3485896 3486789 + Glycerophosphodiester phosphodiesterase Calcium%3B Glycerol metabolism%3B Hydrolase%3B Metal-binding%3B Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols. Belongs to the glycerophosphoryl diester phosphodiesterase family%3B Contains 1 GP-PDE domain%3B KEGG: bli:BL00184 glycerophosphoryl diester phosphodiesterase gene gene3733 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03734 S100141_03735 S100141_03735 S100141_03735 3486812 3488170 + Glycerol-3-phosphate transporter Cell membrane%3B Glycerol metabolism%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Responsible for glycerol-3-phosphate uptake. Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2. A. 1. 4) family gene gene3734 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03735 S100141_03736 S100141_03736 S100141_03736 3488223 3490103 - Chaperone protein HtpG ATP-binding%3B Chaperone%3B Cytoplasm%3B Nucleotide-binding%3B Stress response%3B Molecular chaperone. Has ATPase activity%3B Belongs to the heat shock protein 90 family gene gene3735 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03736 S100141_03737 S100141_03737 S100141_03737 3490530 3492065 + Putative phosphonates utilization ATP-binding protein ATP-binding%3B Nucleotide-binding%3B Transport%3B Belongs to an operon involved in alkylphosphonate uptake and C-P lyase. Exact function not known. PhnK is not required for the ribophosphonate triphosphate (RPnTP) synthase reaction. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene3736 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03737 S100141_03738 S100141_03738 S100141_03738 3492101 3492913 - Putative phosphatase Hydrolase%3B Magnesium%3B Metal-binding%3B Belongs to the HAD-like hydrolase superfamily. Cof family gene gene3737 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03738 S100141_03739 S100141_03739 S100141_03739 3493070 3493612 - sn-glycerol-1-phosphate dehydrogenase Cytoplasm%3B Lipid biosynthesis%3B Lipid metabolism%3B Metal-binding%3B NAD%3B NADP%3B Oxidoreductase%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Zinc%3B Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea%3B Belongs to the glycerol-1-phosphate dehydrogenase family%3B KEGG: bli:BL00250 glycerol-1-phosphate dehydrogenase (NAD(P)+) gene gene3738 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03739 S100141_03740 S100141_03740 S100141_03740 3493675 3494118 - sn-glycerol-1-phosphate dehydrogenase Cytoplasm%3B Lipid biosynthesis%3B Lipid metabolism%3B Metal-binding%3B NAD%3B NADP%3B Nickel%3B Oxidoreductase%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species%3B Belongs to the glycerol-1-phosphate dehydrogenase family%3B KEGG: bli:BL00250 glycerol-1-phosphate dehydrogenase (NAD(P)+) gene gene3739 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03740 S100141_03741 S100141_03741 S100141_03741 3494118 3494768 - hypothetical protein gene gene3740 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03741 S100141_03742 S100141_03742 S100141_03742 3494915 3495376 - hypothetical protein gene gene3741 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03742 S100141_03743 S100141_03743 S100141_03743 3495550 3495696 + hypothetical protein gene gene3742 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03743 S100141_03744 S100141_03744 S100141_03744 3495693 3496508 + Iron(3+)-hydroxamate-binding protein YxeB Cell membrane%3B Ion transport%3B Iron%3B Iron transport%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B Part of the ABC transporter complex FhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Partially required for the transport of desferrioxamine%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene3743 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03744 S100141_03745 S100141_03745 S100141_03745 3496533 3496934 - hypothetical protein gene gene3744 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03745 S100141_03746 S100141_03746 catE catE 3497140 3497508 + Catechol 2%2C3-dioxygenase KEGG: bpf:BpOF4_17485 catechol 2%2C3-dioxygenase gene gene3745 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03746 S100141_03747 S100141_03747 S100141_03747 3497704 3499716 - Ferrous iron transport protein B like protein Cell inner membrane%3B Cell membrane%3B GTP-binding%3B Manganese%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Not involved in Fe(2+) uptake but is involved in manganese uptake. Could be GTP-driven%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. FeoB GTPase (TC 9. A. 8) family%3B Contains 1 FeoB-type G (guanine nucleotide-binding) domain gene gene3746 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03747 S100141_03748 S100141_03748 S100141_03748 3499713 3499940 - hypothetical protein gene gene3747 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03748 S100141_03749 S100141_03749 S100141_03749 3500124 3501212 - Putative membrane-bound acyltransferase YfiQ Acyltransferase%3B Cell membrane%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Belongs to the acyltransferase 3 family gene gene3748 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03749 S100141_03750 S100141_03750 S100141_03750 3501360 3503246 - ABC transporter permease protein YxdM Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex YxdLM which could be involved in peptide resistance. Belongs to the ABC-4 integral membrane protein family gene gene3749 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03750 S100141_03751 S100141_03751 lolD lolD 3503221 3503985 - ATP-binding cassette sub-family A member Alternative splicing%3B ATP-binding%3B Disease mutation%3B Membrane%3B Nucleotide-binding%3B Polymorphism%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Plays an important role in the formation of pulmonary surfactant%2C probably by transporting lipids such as cholesterol. Belongs to the ABC transporter superfamily. ABCA family%3B Contains 2 ABC transporter domains%3B KEGG: cse:Cseg_2118 lipoprotein-releasing system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene3750 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03751 S100141_03752 S100141_03752 S100141_03752 3504077 3505084 - Sensor histidine kinase YxdK ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Probable member of the two-component regulatory system YxdK/YxdJ. May activate YxdJ in response to the antibacterial protein LL-37%3B Contains 1 histidine kinase domain%3B KEGG: ctc:CTC_p22 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene3751 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03752 S100141_03753 S100141_03753 S100141_03753 3505081 3505788 - Response regulator ArlR Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system ArlS/ArlR%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3752 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03753 S100141_03754 S100141_03754 S100141_03754 3505971 3506342 + hypothetical protein gene gene3753 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03754 S100141_03755 S100141_03755 S100141_03755 3506371 3508056 - Putative methyl-accepting chemotaxis protein YoaH Cell membrane%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene3754 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03755 S100141_03756 S100141_03756 S100141_03756 3508183 3509607 - putative transporter YflA Cell membrane%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the sodium:alanine (SAF) symporter family gene gene3755 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03756 S100141_03757 S100141_03757 S100141_03757 3509921 3511051 + NAD(P)(+) transhydrogenase (Re/Si-specific) NAD%3B Oxidoreductase%3B May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer%3B Belongs to the AlaDH/PNT family%3B KEGG: eco:b1603 NAD(P) transhydrogenase subunit alpha gene gene3756 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03757 S100141_03758 S100141_03758 S100141_03758 3511211 3512485 - Arabinogalactan endo-beta-1%2C4-galactanase Calcium%3B Glycosidase%3B Hydrolase%3B Metal-binding%3B Signal%3B Hydrolyzes the beta-1%2C4-galactan linkages of arabinogalactan type I%2C a pectic substance found in plants such as soybeans. Belongs to the glycosyl hydrolase 53 family%3B KEGG: bli:BL00263 arabinogalactan endo-1%2C4-beta-galactosidase gene gene3757 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03758 S100141_03759 S100141_03759 bgaB bgaB 3512590 3514644 - Beta-galactosidase Glycosidase%3B Hydrolase%3B Metal-binding%3B Zinc%3B Hydrolyzes oligosaccharides released by the endo-1%2C4- beta-galactosidase GalA from arabinogalactan type I%2C a pectic plant polysaccharide. It is unable to use lactose as a sole carbon source (By similarity). Catalyzes the hydrolysis of lactose to its constituent monosaccharides glucose and galactose. Possesses a low level of transgalactosylation activity for the production of galacto-oligosaccharides (GOS) from lactose%3B Belongs to the glycosyl hydrolase 42 family%3B KEGG: bli:BL00264 beta-galactosidase gene gene3758 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03759 S100141_03760 S100141_03760 S100141_03760 3514681 3515520 - Putative arabinogalactan oligomer transport system permease protein GanQ Cell membrane%3B Membrane%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Could be part of a binding-protein-dependent transport system for arabinogalactan oligomer%3B probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene3759 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03760 S100141_03761 S100141_03761 S100141_03761 3515524 3516780 - Putative arabinogalactan oligomer transport system permease protein GanP Cell membrane%3B Membrane%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Could be part of a binding-protein-dependent transport system for arabinogalactan oligomer%3B probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene3760 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03761 S100141_03762 S100141_03762 S100141_03762 3516863 3518131 - Cyclodextrin-binding protein Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Sugar transport%3B Transport%3B Binding protein for cyclodextri%3B involved in its cellular uptake. Interacts with all natural cyclodextrins: alpha%2C beta and gamma%3B Belongs to the bacterial solute-binding protein 1 family gene gene3761 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03762 S100141_03763 S100141_03763 S100141_03763 3518276 3519268 - HTH-type transcriptional regulator EbgR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Repressor for beta galactosidase alpha and beta subunits (ebgA and ebgC). Binds lactose as an inducer. Contains 1 HTH lacI-type DNA-binding domain gene gene3762 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03763 S100141_03764 S100141_03764 galK galK 3519524 3520693 + Galactokinase ATP-binding%3B Carbohydrate metabolism%3B Cytoplasm%3B Galactose metabolism%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Transferase%3B Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)%3B Belongs to the GHMP kinase family. GalK subfamily%3B KEGG: bli:BL00191 galactokinase gene gene3763 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03764 S100141_03765 S100141_03765 S100141_03765 3520708 3521709 + UDP-glucose 4-epimerase Carbohydrate metabolism%3B Galactose metabolism%3B Isomerase%3B NAD%3B Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD (By similarity)%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: eal:EAKF1_ch3984 UDP-glucose 4-epimerase gene gene3764 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03765 S100141_03766 S100141_03766 galT galT 3521706 3523193 + UDP-glucose--hexose-1-phosphate uridylyltransferase Carbohydrate metabolism%3B Cytoplasm%3B Galactose metabolism%3B Nucleotidyltransferase%3B Transferase%3B Belongs to the galactose-1-phosphate uridylyltransferase type 2 family%3B KEGG: bli:BL00193 UDPglucose--hexose-1-phosphate uridylyltransferase gene gene3765 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03766 S100141_03767 S100141_03767 S100141_03767 3523230 3524402 - Glucokinase Carbohydrate metabolism%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Xylose metabolism%3B Transcriptional repressor of xylose-utilizing enzymes. Belongs to the ROK (NagC/XylR) family%3B KEGG: tex:Teth514_1432 glucokinase gene gene3766 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03767 S100141_03768 S100141_03768 S100141_03768 3524717 3525448 + Gluconate operon transcriptional repressor DNA-binding%3B Gluconate utilization%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcriptional repressor of the gluconate operon (gntRKPZ)%2C which encodes the proteins for gluconate utilization. Represses mRNA synthesis by binding to the gnt operato%3B the binding is suppressed by gluconate or glucono-delta-lactone. Contains 1 HTH gntR-type DNA-binding domain gene gene3767 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03768 S100141_03769 S100141_03769 gntK gntK 3525441 3526982 + Gluconokinase ATP-binding%3B Gluconate utilization%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the FGGY kinase family%3B KEGG: bsu:BSU40060 gluconokinase gene gene3768 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03769 S100141_03770 S100141_03770 S100141_03770 3527005 3528351 + Gluconate permease Cell membrane%3B Gluconate utilization%3B Membrane%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the GntP permease family gene gene3769 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03770 S100141_03771 S100141_03771 S100141_03771 3528381 3529784 + Phosphogluconate dehydrogenase (NADP(+)-dependent%2C decarboxylating) Gluconate utilization%3B NAD%3B Oxidoreductase%3B Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2)%2C with concomitant reduction of NAD to NADH. Does not contribute to oxidative pentose phosphate (PP) pathway fluxes during growth on glucose. The functional role of GntZ remains obscure%3B Belongs to the 6-phosphogluconate dehydrogenase family%3B KEGG: bsu:BSU40080 6-phosphogluconate dehydrogenase gene gene3770 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03771 S100141_03772 S100141_03772 S100141_03772 3530058 3532661 + Acetaldehyde dehydrogenase (acetylating) NADP%3B Oxidoreductase%3B KEGG: bli:BL00199 acetaldehyde dehydrogenase / alcohol dehydrogenase gene gene3771 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03772 S100141_03773 S100141_03773 S100141_03773 3533125 3533457 + Peroxiredoxin Antioxidant%3B Disulfide bond%3B Oxidoreductase%3B Peroxidase%3B Redox-active center%3B Stress response%3B Directly reduces organic hydroperoxides in its reduced dithiol form. Belongs to the AhpC/TSA family%3B Contains 1 thioredoxin domain%3B KEGG: ssan:NX02_24280 peroxiredoxin (alkyl hydroperoxide reductase subunit C)%3B overlaps another CDS with the same product name gene gene3772 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03773 S100141_03774 S100141_03774 S100141_03774 3533451 3533687 + Peroxiredoxin Antioxidant%3B Disulfide bond%3B Oxidoreductase%3B Peroxidase%3B Redox-active center%3B Stress response%3B Directly reduces organic hydroperoxides in its reduced dithiol form. Belongs to the AhpC/TSA family%3B Contains 1 thioredoxin domain%3B KEGG: sbw:TGUWTKB_1200 peroxiredoxin (alkyl hydroperoxide reductase subunit C)%3B overlaps another CDS with the same product name gene gene3773 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03774 S100141_03775 S100141_03775 ahpF ahpF 3533701 3535230 + NADH dehydrogenase Cell membrane%3B Disulfide bond%3B Electron transport%3B FAD%3B Flavoprotein%3B Membrane%3B NAD%3B Oxidoreductase%3B Redox-active center%3B Transport%3B Ubiquinone%3B Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)%3B Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: meh:M301_0244 alkyl hydroperoxide reductase subunit F%3B With a disulfide as acceptor gene gene3774 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03775 S100141_03776 S100141_03776 S100141_03776 3535800 3536429 - hypothetical protein gene gene3775 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03776 S100141_03777 S100141_03777 S100141_03777 3536497 3537513 - hypothetical protein gene gene3776 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03777 S100141_03778 S100141_03778 S100141_03778 3537698 3539341 + uncharacterized protein Cytoplasm%3B Nucleus. gene gene3777 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03778 S100141_03779 S100141_03779 S100141_03779 3539332 3539649 + dCTP diphosphatase KEGG: cit:102607840 dCTP diphosphatase gene gene3778 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03779 S100141_03780 S100141_03780 S100141_03780 3539931 3540827 + Nucleotide-binding protein ExpZ ATP-binding%3B Nucleotide-binding%3B Repeat%3B Belongs to the ABC transporter superfamily%3B Contains 2 ABC transporter domains gene gene3779 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03780 S100141_03781 S100141_03781 S100141_03781 3540829 3541377 + Putative transport permease YvfS Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the ABC-2 integral membrane protein family%3B Contains 1 ABC transmembrane type-2 domain gene gene3780 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03781 S100141_03782 S100141_03782 S100141_03782 3541568 3542575 + Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system YvfT/YvfU. Probably activates YvfU by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: blh:BaLi_c43020 two-component system%2C NarL family%2C sensor histidine kinase DesK%3B overlaps another CDS with the same product name gene gene3781 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03782 S100141_03783 S100141_03783 S100141_03783 3542547 3542708 + Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system YvfT/YvfU. Probably activates YvfU by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bld:BLi04303 two-component system%2C NarL family%2C sensor histidine kinase DesK%3B overlaps another CDS with the same product name gene gene3782 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03783 S100141_03784 S100141_03784 S100141_03784 3542705 3543298 + putative transcriptional regulatory protein YvfU Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system YvfT/YvfU%3B Contains 1 HTH luxR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3783 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03784 S100141_03785 S100141_03785 S100141_03785 3543946 3545919 - hypothetical protein gene gene3784 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03785 S100141_03786 S100141_03786 S100141_03786 3546266 3546622 - hypothetical protein gene gene3785 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03786 S100141_03787 S100141_03787 S100141_03787 3546619 3547314 - Manganese transport system ATP-binding protein MntB ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Transport%3B This protein is probably a component of a manganese permease%2C a binding protein-dependent%2C ATP-driven transport system. Probably responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene3786 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03787 S100141_03788 S100141_03788 S100141_03788 3548277 3548657 - hypothetical protein gene gene3787 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03788 S100141_03789 S100141_03789 S100141_03789 3549440 3549598 + hypothetical protein gene gene3788 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03789 S100141_03790 S100141_03790 rlmH rlmH 3550326 3550805 - 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase Cytoplasm%3B Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA%3B Belongs to the RNA methyltransferase RlmH family%3B KEGG: bli:BL02382 23S rRNA (pseudouridine1915-N3)-methyltransferase gene gene3789 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03790 S100141_03791 S100141_03791 S100141_03791 3550886 3551044 - uncharacterized protein gene gene3790 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03791 S100141_03792 S100141_03792 S100141_03792 3551243 3551782 - hypothetical protein gene gene3791 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03792 S100141_03793 S100141_03793 S100141_03793 3552156 3552677 - Phosphinothricin acetyltransferase Acyltransferase%3B Transferase%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: gwc:GWCH70_2852 phosphinothricin acetyltransferase gene gene3792 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03793 S100141_03794 S100141_03794 S100141_03794 3552705 3553175 - hypothetical protein gene gene3793 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03794 S100141_03795 S100141_03795 S100141_03795 3553432 3554277 - Adenosyl-chloride synthase Chloride%3B S-adenosyl-L-methionine%3B Transferase%3B Involved in the biosynthesis of the proteosome inhibitor salinosporamide A (SalA). Catalyzes the halogenation of S- adenosyl-L-methionine (SAM) with chloride to generate 5'-chloro- 5'-deoxyadenosine (5'-CIDA) and L-methionine. It can also use bromide and iodide%2C producing halogenated 5'-deoxyadenosine (5'- XDA) and L-methionine%2C however no halogenase activity is detected in the presence of fluoride%3B Belongs to the SalL family gene gene3794 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03795 S100141_03796 S100141_03796 S100141_03796 3554574 3555785 - Peptidase Do Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Serine protease%3B Transmembrane%3B Transmembrane helix%3B Belongs to the peptidase S1C family%3B Contains 1 PDZ (DHR) domain%3B KEGG: afl:Aflv_2834 serine protease Do gene gene3795 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03796 S100141_03797 S100141_03797 S100141_03797 3555868 3556662 - Putative metallo-hydrolase YycJ Hydrolase%3B Metal-binding%3B Belongs to the metallo-beta-lactamase superfamily%3B KEGG: rch:RUM_07740 ribonuclease J%3B Acting on ester bonds gene gene3796 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03797 S100141_03798 S100141_03798 S100141_03798 3556677 3557525 - Two-component system YycFG regulatory protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Together with YycH%2C regulates the activity of the two- component system YycF/YycG gene gene3797 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03798 S100141_03799 S100141_03799 S100141_03799 3557512 3558876 - Two-component system YycF/YycG regulatory protein YycH Calcium%3B Cell membrane%3B Membrane%3B Metal-binding%3B Transmembrane%3B Transmembrane helix%3B Together with YycI%2C regulates the activity of the two- component system YycF/YycG gene gene3798 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03799 S100141_03800 S100141_03800 vicK vicK 3558866 3560710 - Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon%2C the yocH and ykvT%2C cwlO%2C lytE%2C ydjM%2C yjeA%2C yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B Contains 1 PAC (PAS-associated C-terminal) domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bli:BL02372 two-component system%2C OmpR family%2C sensor histidine kinase VicK gene gene3799 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03800 S100141_03801 S100141_03801 S100141_03801 3560718 3561425 - Phosphate regulon transcriptional regulatory protein Activator%3B Cytoplasm%3B DNA-binding%3B Phosphate transport%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Transport%3B Two-component regulatory system%3B This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited (By similarity)%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3800 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03801 S100141_03802 S100141_03802 S100141_03802 3561844 3561916 - tRNA-Phe tRNA gene3801 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03802 S100141_03803 S100141_03803 S100141_03803 3561943 3562019 - tRNA-Asp tRNA gene3802 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03803 S100141_03804 S100141_03804 S100141_03804 3562108 3562179 - tRNA-Glu tRNA gene3803 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03804 S100141_03805 S100141_03805 S100141_03805 3562187 3562262 - tRNA-Lys tRNA gene3804 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03805 S100141_03806 S100141_03806 S100141_03806 3562478 3562891 - 8-oxo-dGTP diphosphatase Hydrolase%3B Magnesium%3B Manganese%3B Metal-binding%3B Probably mediates the hydrolysis of some nucleoside diphosphate derivatives%3B Belongs to the Nudix hydrolase family%3B Contains 1 nudix hydrolase domain%3B KEGG: blh:BaLi_c43220 8-oxo-dGTP diphosphatase gene gene3805 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03806 S100141_03807 S100141_03807 purA purA 3562955 3564247 - Adenylosuccinate synthase Cytoplasm%3B GTP-binding%3B Ligase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Purine biosynthesis%3B Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP%3B Belongs to the adenylosuccinate synthetase family%3B KEGG: vvu:VV2_0768 adenylosuccinate synthase gene gene3806 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03807 S100141_03808 S100141_03808 S100141_03808 3564512 3564778 + hypothetical protein gene gene3807 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03808 S100141_03809 S100141_03809 S100141_03809 3564796 3566160 - DNA helicase ATP-binding%3B DNA replication%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Primosome%3B Belongs to the helicase family. DnaB subfamily%3B Contains 1 SF4 helicase domain%3B KEGG: bsu:BSU40440 replicative DNA helicase gene gene3808 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03809 S100141_03810 S100141_03810 S100141_03810 3566354 3566551 + uncharacterized protein gene gene3809 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03810 S100141_03811 S100141_03811 S100141_03811 3566589 3566807 - hypothetical protein gene gene3810 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03811 S100141_03812 S100141_03812 S100141_03812 3566950 3567087 + uncharacterized protein gene gene3811 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03812 S100141_03813 S100141_03813 S100141_03813 3567158 3568363 + 2-nitroimidazole transporter Antibiotic resistance%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in efflux of 2-nitroimidazole%3B Belongs to the major facilitator superfamily. Cyanate porter (TC 2. A. 1. 17) family gene gene3812 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03813 S100141_03814 S100141_03814 S100141_03814 3568496 3569746 + N-acetylglucosamine-6-phosphate deacetylase Carbohydrate metabolism%3B Hydrolase%3B Iron%3B Metal-binding%3B Involved in the first committed step in the biosynthesis of amino-sugar-nucleotides. Catalyzes the hydrolysis of the N- acetyl group of N-acetylglucosamine-6-phosphate (GlcNAc-6-P) to yield glucosamine 6-phosphate and acetate%3B Belongs to the NagA family%3B KEGG: bli:BL00084 N-acetylglucosamine-6-phosphate deacetylase gene gene3813 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03814 S100141_03815 S100141_03815 nagB nagB 3569743 3570489 + Glucosamine-6-phosphate deaminase Carbohydrate metabolism%3B Hydrolase%3B Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion%3B Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily%3B KEGG: bli:BL00085 glucosamine-6-phosphate deaminase gene gene3814 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03815 S100141_03816 S100141_03816 S100141_03816 3570486 3571217 + HTH-type transcriptional repressor YvoA DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Acts as a weak repressor of yflG expression%3B Contains 1 HTH gntR-type DNA-binding domain gene gene3815 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03816 S100141_03817 S100141_03817 murQ murQ 3571214 3572110 + N-acetylmuramic acid 6-phosphate etherase Carbohydrate metabolism%3B Lyase%3B Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate%2C producing GlcNAc 6- phosphate and D-lactate%3B Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily%3B Contains 1 SIS domain%3B KEGG: syd:Syncc9605_1393 N-acetylmuramic acid 6-phosphate etherase gene gene3816 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03817 S100141_03818 S100141_03818 nagE nagE 3572113 3573486 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Kinase%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylglucosamine transport (By similarity)%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bli:BL00088 PTS system%2C N-acetylglucosamine-specific IIB component gene gene3817 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03818 S100141_03819 S100141_03819 S100141_03819 3573523 3573972 - 50S ribosomal protein L9 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Binds to the 23S rRNA%3B Belongs to the ribosomal protein L9P family gene gene3818 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03819 S100141_03820 S100141_03820 S100141_03820 3573969 3575951 - uncharacterized protein Contains 1 GGDEF domain gene gene3819 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03820 S100141_03821 S100141_03821 S100141_03821 3575987 3576880 - uncharacterized protein gene gene3820 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03821 S100141_03822 S100141_03822 S100141_03822 3577428 3577904 + Spore coat protein Sporulation%3B Belongs to the CotF family gene gene3821 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03822 S100141_03823 S100141_03823 S100141_03823 3577947 3578366 - TRAP-T-associated universal stress protein TeaD ATP-binding%3B Cytoplasm%3B Nucleotide-binding%3B ATP-binding protein that negatively regulates activity of the tripartite ATP-independent periplasmic (TRAP) ectoine transport system TeaABC. May regulate uptake according to the ATP status of the cell%3B Belongs to the universal stress protein A family gene gene3822 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03823 S100141_03824 S100141_03824 S100141_03824 3578384 3579850 - Bicarbonate transporter BicA Cell inner membrane%3B Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Low/medium affinity%2C Na(+)-dependent bicarbonate transporter%3B Belongs to the SLC26A/SulP transporter (TC 2. A. 53) family%3B Contains 1 STAS domain gene gene3823 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03824 S100141_03825 S100141_03825 S100141_03825 3580066 3581367 + putative transporter YybO Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily. Phthalate permease family gene gene3824 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03825 S100141_03826 S100141_03826 S100141_03826 3581445 3581684 - 30S ribosomal protein S18 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA%2C where it helps stabilize the platform of the 30S subunit%3B Belongs to the ribosomal protein S18P family gene gene3825 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03826 S100141_03827 S100141_03827 S100141_03827 3581736 3582248 - Single-stranded DNA-binding protein DNA damage%3B DNA recombination%3B DNA repair%3B DNA replication%3B DNA-binding%3B Plays an important role in DNA replication%2C recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism%3B Contains 1 SSB domain gene gene3826 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03827 S100141_03828 S100141_03828 S100141_03828 3582295 3582582 - 30S ribosomal protein S6%2C chloroplastic Chloroplast%3B Plastid%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Binds together with S18 to 16S ribosomal RNA%3B Belongs to the ribosomal protein S6P family gene gene3827 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03828 S100141_03829 S100141_03829 S100141_03829 3582696 3583796 - Ribosome-binding ATPase YchF ATP-binding%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner%3B Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily%3B Contains 1 OBG-type G (guanine nucleotide-binding) domain gene gene3828 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03829 S100141_03830 S100141_03830 S100141_03830 3583975 3584184 - uncharacterized protein gene gene3829 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03830 S100141_03831 S100141_03831 S100141_03831 3584269 3585267 - uncharacterized protein gene gene3830 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03831 S100141_03832 S100141_03832 S100141_03832 3585586 3586203 + uncharacterized protein gene gene3831 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03832 S100141_03833 S100141_03833 S100141_03833 3586240 3587088 - Stage 0 sporulation protein J Chromosome partition%3B DNA-binding%3B Sporulation%3B Required for the initiation of sporulation and for normal chromosome segregation. Antagonizes sporulation inhibition by Soj. It probably interacts with a specific DNA site and other proteins involved in partitioning and cell division%2C and antagonizes Soj in response to cell cycle events related to chromosome partitioning%3B Belongs to the ParB family gene gene3832 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03833 S100141_03834 S100141_03834 S100141_03834 3587081 3587842 - Putative septum site-determining protein MinD ATP-binding%3B Cell cycle%3B Cell division%3B Chloroplast%3B Nucleotide-binding%3B Plastid%3B Septation%3B ATPase required for the correct placement of the division site%3B Belongs to the ParA family. MinD subfamily gene gene3833 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03834 S100141_03835 S100141_03835 S100141_03835 3588085 3588528 - uncharacterized protein gene gene3834 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03835 S100141_03836 S100141_03836 S100141_03836 3588595 3589452 - hypothetical protein gene gene3835 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03836 S100141_03837 S100141_03837 S100141_03837 3589508 3590359 - Nucleoid occlusion protein Cell cycle%3B Cell division%3B Cytoplasm%3B DNA-binding%3B Septation%3B Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid%2C especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid%2C which would cause chromosome breakage%3B Belongs to the ParB family gene gene3836 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03837 S100141_03838 S100141_03838 gidB gidB 3590457 3591209 - 16S rRNA (guanine(527)-N(7))-methyltransferase Cytoplasm%3B Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B Specifically methylates the N7 position of guanine in position 535 of 16S rRNA%3B Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family%3B KEGG: bli:BL00108 16S rRNA (guanine527-N7)-methyltransferase gene gene3837 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03838 S100141_03839 S100141_03839 S100141_03839 3591190 3593076 - tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG Cytoplasm%3B FAD%3B Flavoprotein%3B NAD%3B tRNA processing%3B NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs%2C forming tRNA-cmnm(5)s(2)U34%3B Belongs to the MnmG family gene gene3838 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03839 S100141_03840 S100141_03840 mnmE mnmE 3593093 3594472 - tRNA modification GTPase MnmE Cytoplasm%3B GTP-binding%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Potassium%3B tRNA processing%3B Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs%2C forming tRNA- cmnm(5)s(2)U34%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. TrmE GTPase family%3B Contains 1 TrmE-type G (guanine nucleotide-binding) domain%3B KEGG: bsu:BSU41020 tRNA modification GTPase%3B Acting on acid anhydrides gene gene3839 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03840 S100141_03841 S100141_03841 S100141_03841 3594807 3595430 - Protein jag RNA-binding%3B Contains 1 KH domain%3B Contains 1 R3H domain gene gene3840 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03841 S100141_03842 S100141_03842 S100141_03842 3595427 3596224 - Membrane protein insertase MisCA Cell membrane%3B Chaperone%3B Lipoprotein%3B Membrane%3B Palmitate%3B Protein transport%3B Signal%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex%2C as well as at least some lipoproteins (By similarity). Also involved in protein secretion processes. Essential for sporulation by activating sigma factor SpoIIIG/SigG after engulfment is completed in the prespore%2C maybe by acting on SpoIIIAE. It has an overlapping%2C although partly distinct%2C function compared to YqjG(MisCB)%3B Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily gene gene3841 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03842 S100141_03843 S100141_03843 rnpA rnpA 3596394 3596687 - Ribonuclease P Endonuclease%3B Hydrolase%3B Nuclease%3B RNA-binding%3B tRNA processing%3B RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4. 5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme%3B Belongs to the RnpA family%3B KEGG: bsu:BSU41050 ribonuclease P protein component gene gene3842 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03843 S100141_03844 S100141_03844 S100141_03844 3597612 3598952 + Chromosomal replication initiator protein DnaA ATP-binding%3B Cytoplasm%3B DNA replication%3B DNA-binding%3B Nucleotide-binding%3B Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replicatio%3B it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids%3B Belongs to the DnaA family gene gene3843 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03844 S100141_03845 S100141_03845 dnaN dnaN 3599129 3600265 + DNA-directed DNA polymerase Cytoplasm%3B DNA replication%3B DNA-directed DNA polymerase%3B Nucleotidyltransferase%3B Transferase%3B KEGG: psj:PSJM300_00010 DNA polymerase III subunit beta gene gene3844 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03845 S100141_03846 S100141_03846 S100141_03846 3600433 3600648 + uncharacterized protein RNA-binding%3B Contains 1 S4 RNA-binding domain gene gene3845 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03846 S100141_03847 S100141_03847 S100141_03847 3600665 3601777 + DNA replication and repair protein RecF ATP-binding%3B Cytoplasm%3B DNA damage%3B DNA repair%3B DNA replication%3B DNA-binding%3B Nucleotide-binding%3B SOS response%3B The RecF protein is involved in DNA metabolis%3B it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded%2C linear DNA. It also seems to bind ATP%3B Belongs to the RecF family gene gene3846 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03847 S100141_03848 S100141_03848 gyrB gyrB 3602091 3604010 + DNA topoisomerase (ATP-hydrolyzing) ATP-binding%3B DNA-binding%3B Isomerase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Topoisomerase%3B Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule%3B Belongs to the type II topoisomerase family. ParE type 2 subfamily%3B Contains 1 Toprim domain%3B KEGG: bli:BL00081 DNA gyrase subunit B gene gene3847 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03848 S100141_03849 S100141_03849 gyrA gyrA 3604201 3606669 + DNA topoisomerase (ATP-hydrolyzing) ATP-binding%3B Cytoplasm%3B DNA-binding%3B Isomerase%3B Nucleotide-binding%3B Topoisomerase%3B DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings%2C including catenanes and knotted rings%3B Belongs to the topoisomerase GyrA/ParC subunit family%3B KEGG: bli:BL00082 DNA gyrase subunit A gene gene3848 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03849 S100141_03850 S100141_03850 S100141_03850 3607007 3608556 + 16S ribosomal RNA rRNA gene3849 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03850 S100141_03851 S100141_03851 S100141_03851 3608659 3608735 + tRNA-Ile tRNA gene3850 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03851 S100141_03852 S100141_03852 S100141_03852 3608747 3608822 + tRNA-Ala tRNA gene3851 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03852 S100141_03853 S100141_03853 S100141_03853 3608893 3611823 + 23S ribosomal RNA rRNA gene3852 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03853 S100141_03854 S100141_03854 S100141_03854 3611955 3612070 + 5S ribosomal RNA rRNA gene3853 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03854 S100141_03855 S100141_03855 S100141_03855 3612086 3613063 - uncharacterized protein gene gene3854 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03855 S100141_03856 S100141_03856 S100141_03856 3613185 3614651 + IMP dehydrogenase CBS domain%3B GMP biosynthesis%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Potassium%3B Purine biosynthesis%3B Repeat%3B Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP)%2C the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides%2C and therefore plays an important role in the regulation of cell growth%3B Belongs to the IMPDH/GMPR family%3B Contains 2 CBS domains%3B KEGG: bsu:BSU00090 IMP dehydrogenase gene gene3855 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03856 S100141_03857 S100141_03857 S100141_03857 3614806 3616131 + Serine-type D-Ala-D-Ala carboxypeptidase Carboxypeptidase%3B Cell shape%3B Cell wall%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Peptidoglycan synthesis%3B Protease%3B Secreted%3B Signal%3B Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. Belongs to the peptidase S11 family%3B KEGG: bss:BSUW23_00055 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6) gene gene3856 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03857 S100141_03858 S100141_03858 pdxS pdxS 3616318 3617202 + Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) Lyase%3B Pyridoxal phosphate%3B Schiff base%3B Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP)%2C glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates%2C resulting from enzyme-catalyzed isomerization of RBP and G3P%2C respectively%3B Belongs to the PdxS/SNZ family%3B KEGG: bsu:BSU00110 pyridoxal 5'-phosphate synthase pdxS subunit gene gene3857 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03858 S100141_03859 S100141_03859 pdxT pdxT 3617224 3617814 + Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) Glutamine amidotransferase%3B Hydrolase%3B Lyase%3B Pyridoxal phosphate%3B Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS%3B Belongs to the glutaminase PdxT/SNO family%3B KEGG: bsu:BSU00120 5'-phosphate synthase pdxT subunit gene gene3858 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03859 S100141_03860 S100141_03860 sarS sarS 3618142 3619419 + Serine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine%2C to form the misacylated tRNA L-seryl-tRNA(Sec)%2C which will be further converted into selenocysteinyl-tRNA(Sec)%3B Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily%3B KEGG: dps:DP1764 seryl-tRNA synthetase gene gene3859 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03860 S100141_03861 S100141_03861 glxK glxK 3619449 3620579 - Glycerate 3-kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the glycerate kinase type-1 family%3B KEGG: eco:b0514 glycerate kinase gene gene3860 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03861 S100141_03862 S100141_03862 S100141_03862 3620595 3621179 - putative transporter Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the CitM (TC 2. A. 11) transporter family%3B overlaps another CDS with the same product name gene gene3861 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03862 S100141_03863 S100141_03863 S100141_03863 3621127 3621861 - putative transporter Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the CitM (TC 2. A. 11) transporter family%3B overlaps another CDS with the same product name gene gene3862 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03863 S100141_03864 S100141_03864 S100141_03864 3621951 3623069 - Carbohydrate diacid regulator Transcription%3B Transcription regulation%3B Seems to regulate the expression of the operons for the enzymes involved in D-galactarate%2C D-glucarate and D-glycerate utilization. Belongs to the CdaR family gene gene3863 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03864 S100141_03865 S100141_03865 S100141_03865 3623099 3623521 - hypothetical protein gene gene3864 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03865 S100141_03866 S100141_03866 S100141_03866 3623651 3623743 + tRNA-Ser tRNA gene3865 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03866 S100141_03867 S100141_03867 S100141_03867 3623877 3624518 - Deoxyadenosine kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Plays an essential role in generating the deoxyribonucleotide precursors dATP AND dCTP for DNA metabolism. The phosphate acceptor specificity is strict toward deoxyadenosine (dAdo) and deoxycytidine (dCyd). The specificity toward the sugar moiety of the nucleoside is less strict. Both 2-deoxyribose%2C ribose%2C and arabinose nucleosides are phosphorylated%2C although the 2-deoxyribonucleosides are preferred. The phosphate donor specificity is dependent on the deoxyribonucleoside substrate%2C but GTP is efficient with both deoxycytidine and deoxyadenosine. Only nucleoside triphosphates can act as phosphate donors%3B Belongs to the DCK/DGK family%3B KEGG: bli:BL02366 deoxyadenosine/deoxycytidine kinase gene gene3866 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03867 S100141_03868 S100141_03868 S100141_03868 3624515 3625138 - Deoxyguanosine kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as phosphate donor than CTP%2C ATP and GTP%3B Belongs to the DCK/DGK family%3B KEGG: bsu:BSU00150 deoxyguanosine kinase gene gene3867 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03868 S100141_03869 S100141_03869 S100141_03869 3625225 3626544 - putative cell wall hydrolase LytN Cell wall biogenesis/degradation%3B Hydrolase%3B Secreted%3B Signal%3B Probably involved in peptidoglycan hydrolysis. Contains 1 LysM repeat%3B Contains 1 peptidase C51 domain gene gene3868 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03869 S100141_03870 S100141_03870 S100141_03870 3626582 3627124 - Isochorismatase Hydrolase%3B Belongs to the isochorismatase family%3B KEGG: cko:CKO_02566 bifunctional isochorismate lyase / aryl carrier protein gene gene3869 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03870 S100141_03871 S100141_03871 tadA tadA 3627213 3627695 + tRNA(adenine(34)) deaminase Hydrolase%3B Metal-binding%3B tRNA processing%3B Zinc%3B Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)%3B Belongs to the cytidine and deoxycytidylate deaminase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: eca:ECA3260 tRNA(adenine34) deaminase gene gene3870 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03871 S100141_03872 S100141_03872 dnaX dnaX 3628181 3629881 + DNA-directed DNA polymerase ATP-binding%3B DNA replication%3B DNA-directed DNA polymerase%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase%3B DNA polymerase III is a complex%2C multichain enzyme responsible for most of the replicative synthesis in bacteria. Belongs to the DnaX/STICHEL family%3B KEGG: bsu:BSU00190 DNA polymerase III subunit gamma/tau gene gene3871 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03872 S100141_03873 S100141_03873 S100141_03873 3629908 3630231 + Nucleoid-associated protein Cytoplasm%3B DNA-binding%3B Binds to DNA and alters its conformation. May be involved in regulation of gene expression%2C nucleoid organization and DNA protection%3B Belongs to the YbaB/EbfC family gene gene3872 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03873 S100141_03874 S100141_03874 S100141_03874 3630245 3630841 + Recombination protein RecR DNA damage%3B DNA recombination%3B DNA repair%3B Metal-binding%3B Zinc%3B Zinc-finger%3B May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO%3B Belongs to the RecR family%3B Contains 1 Toprim domain gene gene3873 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03874 S100141_03875 S100141_03875 S100141_03875 3630862 3631086 + uncharacterized protein gene gene3874 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03875 S100141_03876 S100141_03876 S100141_03876 3631100 3631417 + Sigma-K factor-processing regulatory protein BofA Membrane%3B Metal-binding%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Zinc%3B Involved in the mediation of the intercompartmental coupling of pro-sigma K processing to events in the forespore. Inhibits SpoIVFB-processing activity until a signal has been received from the forespore. Could inhibit SpoIVFB metalloprotease activity by coordinating a zinc in the SpoIVFB active site%2C preventing access of a water molecule and the sequence of pro- sigma K%2C which are necessary for peptide bond hydrolysis to produce sigma-K gene gene3875 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03876 S100141_03877 S100141_03877 S100141_03877 3631704 3633253 + 16S ribosomal RNA rRNA gene3876 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03877 S100141_03878 S100141_03878 S100141_03878 3633356 3633432 + tRNA-Ile tRNA gene3877 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03878 S100141_03879 S100141_03879 S100141_03879 3633444 3633519 + tRNA-Ala tRNA gene3878 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03879 S100141_03880 S100141_03880 S100141_03880 3633590 3636520 + 23S ribosomal RNA rRNA gene3879 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03880 S100141_03881 S100141_03881 S100141_03881 3636653 3636768 + 5S ribosomal RNA rRNA gene3880 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03881 S100141_03882 S100141_03882 S100141_03882 3636937 3637128 + Protein CsfB gene gene3881 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03882 S100141_03883 S100141_03883 S100141_03883 3637321 3637938 + Protein XpaC Hydrolase. gene gene3882 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03883 S100141_03884 S100141_03884 S100141_03884 3637954 3639147 + uncharacterized protein Belongs to the TelA family gene gene3883 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03884 S100141_03885 S100141_03885 ldcC ldcC 3639288 3640730 + Lysine decarboxylase Decarboxylase%3B Lyase%3B Pyridoxal phosphate%3B Belongs to the Orn/Lys/Arg decarboxylase class-I family%3B KEGG: bca:BCE_0027 lysine decarboxylase gene gene3884 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03885 S100141_03886 S100141_03886 S100141_03886 3640727 3641365 + dTMP kinase ATP-binding%3B Kinase%3B Nucleotide biosynthesis%3B Nucleotide-binding%3B Transferase%3B Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis%3B Belongs to the thymidylate kinase family%3B KEGG: pol:Bpro_2519 dTMP kinase gene gene3885 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03886 S100141_03887 S100141_03887 S100141_03887 3641441 3641770 + uncharacterized protein gene gene3886 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03887 S100141_03888 S100141_03888 S100141_03888 3641782 3642222 + uncharacterized protein gene gene3887 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03888 S100141_03889 S100141_03889 holB holB 3642234 3643223 + DNA-directed DNA polymerase DNA replication%3B DNA-directed DNA polymerase%3B Nucleotidyltransferase%3B Transferase%3B KEGG: bli:BL00541 DNA polymerase III subunit delta' gene gene3888 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03889 S100141_03890 S100141_03890 S100141_03890 3643226 3644053 + Stage 0 sporulation protein YaaT Cytoplasm%3B Sporulation%3B Essential for the phosphorelay during initiation of sporulation. May control the level of phosphorylated spo0A through spo0E activity during sporulation%3B Contains 1 PSP1 C-terminal domain gene gene3889 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03890 S100141_03891 S100141_03891 S100141_03891 3644068 3644430 + Initiation-control protein YabA DNA replication%3B Involved in initiation control of chromosome replication%3B Belongs to the YabA family gene gene3890 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03891 S100141_03892 S100141_03892 S100141_03892 3644495 3645238 + uncharacterized protein gene gene3891 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03892 S100141_03893 S100141_03893 S100141_03893 3645225 3645518 + UPF0213 protein Belongs to the UPF0213 family%3B Contains 1 GIY-YIG domain gene gene3892 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03893 S100141_03894 S100141_03894 rsmI rsmI 3645490 3646368 + 16S rRNA (cytidine(1402)-2'-O)-methyltransferase Cytoplasm%3B Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA%3B Belongs to the methyltransferase superfamily. RsmI family%3B KEGG: bli:BL00535 16S rRNA (cytidine1402-2'-O)-methyltransferase gene gene3893 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03894 S100141_03895 S100141_03895 S100141_03895 3646417 3646701 - Transition state regulatory protein AbrB Activator%3B DNA-binding%3B Repressor%3B Sporulation%3B Transcription%3B Transcription regulation%3B Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites%2C it may be the sole repressor of tycA transcription%3B Contains 1 SpoVT-AbrB domain%3B To B. subtilis Abh and SpoVT gene gene3894 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03895 S100141_03896 S100141_03896 marS marS 3647215 3649203 + Methionine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B RNA-binding%3B tRNA-binding%3B Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation%3B Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily%3B Contains 1 tRNA-binding domain%3B KEGG: bli:BL00533 methionyl-tRNA synthetase gene gene3895 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03896 S100141_03897 S100141_03897 tatD tatD 3649288 3650055 + putative metal-dependent hydrolase YabD Hydrolase%3B Metal-binding%3B Belongs to the TatD-type hydrolase family%3B KEGG: bsu:BSU00390 TatD DNase family protein%3B Endodeoxyribonucleases producing 5'-phosphomonoesters gene gene3896 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03897 S100141_03898 S100141_03898 S100141_03898 3650085 3651497 + uncharacterized protein Contains 1 G5 domain gene gene3897 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03898 S100141_03899 S100141_03899 rnmV rnmV 3651665 3652225 + Ribonuclease M5 Cytoplasm%3B Endonuclease%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nuclease%3B Ribosome biogenesis%3B RNA-binding%3B rRNA processing%3B rRNA-binding%3B Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step%3B Belongs to the ribonuclease M5 family%3B Contains 1 Toprim domain%3B KEGG: bsu:BSU00410 ribonuclease M5 gene gene3898 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03899 S100141_03900 S100141_03900 ksgA ksgA 3652218 3653096 + 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase Cytoplasm%3B Methyltransferase%3B RNA-binding%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily%3B KEGG: bsu:BSU00420 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase gene gene3899 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03900 S100141_03901 S100141_03901 S100141_03901 3653255 3654136 + Sporulation-specific protease YabG Hydrolase%3B Membrane%3B Sporulation%3B Cleaves the spore coat proteins SpoIVA and SafA. May cooperate with tgl to mediate the temperature-dependent cross- linking of coat proteins like GerQ%3B Belongs to the peptidase U57 family gene gene3900 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03901 S100141_03902 S100141_03902 S100141_03902 3654361 3654621 + Protein Veg Cytoplasm%3B Sporulation%3B Stimulates biofilm formation via transcriptional activation of extracellular matrix genes. Acts by repressing SinR activity%2C independently of the SinI%2C SlrA and SlrR pathways. Could also be involved in the regulation of other genes during biofilm and spore formation gene gene3901 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03902 S100141_03903 S100141_03903 S100141_03903 3654778 3654963 + Protein SspF DNA-binding%3B Sporulation%3B May play some important role in either sporulation or the dormant spore. Belongs to the alpha/beta-type SASP family gene gene3902 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03903 S100141_03904 S100141_03904 S100141_03904 3655018 3655188 - hypothetical protein gene gene3903 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03904 S100141_03905 S100141_03905 ispE ispE 3655261 3656130 + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase ATP-binding%3B Isoprene biosynthesis%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol%3B Belongs to the GHMP kinase family. IspE subfamily%3B KEGG: rhl:LPU83_0984 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase gene gene3904 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03905 S100141_03906 S100141_03906 S100141_03906 3656187 3657020 + Pur operon repressor DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Controls the transcription of the pur operon for purine biosynthetic genes%2C binds to the control region of the operon. DNA binding is inhibited by 5-phosphoribosyl 1-pyrophosphate. Belongs to the purine/pyrimidine phosphoribosyltransferase family gene gene3905 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03906 S100141_03907 S100141_03907 ridA ridA 3657038 3657415 + 2-iminobutanoate/2-iminopropanoate deaminase Belongs to the RutC family%3B KEGG: bcib:IM45_599 2-iminobutanoate/2-iminopropanoate deaminase gene gene3906 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03907 S100141_03908 S100141_03908 S100141_03908 3657595 3657888 + Putative septation protein SpoVG Cell cycle%3B Cell division%3B Septation%3B Could be involved in septation%3B Belongs to the SpoVG family gene gene3907 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03908 S100141_03909 S100141_03909 glmU glmU 3658193 3659563 + UDP-N-acetylglucosamine diphosphorylase Acyltransferase%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Magnesium%3B Metal-binding%3B Multifunctional enzyme%3B Nucleotidyltransferase%3B Peptidoglycan synthesis%3B Repeat%3B Transferase%3B Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P)%2C which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate)%2C a reaction catalyzed by the N-terminal domain%3B In the N-terminal sectio%3B belongs to the N- acetylglucosamine-1-phosphate uridyltransferase family%3B In the C-terminal sectio%3B belongs to the transferase hexapeptide repeat family%3B KEGG: bsu:BSU00500 bifunctional UDP-N-acetylglucosamine pyrophosphorylase / Glucosamine-1-phosphate N-acetyltransferase gene gene3908 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03909 S100141_03910 S100141_03910 prpS prpS 3659584 3660534 + Ribose-phosphate diphosphokinase ATP-binding%3B Cytoplasm%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide biosynthesis%3B Nucleotide-binding%3B Transferase%3B Involved in the biosynthesis of ribose 1%2C5-bisphosphate. Catalyzes the transfer of pyrophosphoryl group from ATP to ribose- 5-phosphate to yield phosphoribosyl diphosphate (PRPP) and AMP%3B Belongs to the ribose-phosphate pyrophosphokinase family%3B KEGG: bli:BL00519 ribose-phosphate pyrophosphokinase gene gene3909 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03910 S100141_03911 S100141_03911 S100141_03911 3660615 3661241 + 50S ribosomal protein L25 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance%3B Belongs to the ribosomal protein L25P family. CTC subfamily gene gene3910 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03911 S100141_03912 S100141_03912 pth1 pth1 3661358 3661924 + Aminoacyl-tRNA hydrolase Cytoplasm%3B Hydrolase%3B The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis%3B Belongs to the PTH family%3B KEGG: mlo:mlr2694 peptidyl-tRNA hydrolase%2C PTH1 family gene gene3911 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03912 S100141_03913 S100141_03913 S100141_03913 3661981 3662211 + uncharacterized protein gene gene3912 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03913 S100141_03914 S100141_03914 S100141_03914 3662276 3665809 + Transcription-repair-coupling factor ATP-binding%3B Cytoplasm%3B DNA damage%3B DNA repair%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA%2C and recruitment of nucleotide excision repair machinery to the damaged site%3B In the N-terminal sectio%3B belongs to the UvrB family%3B In the C-terminal sectio%3B belongs to the helicase family. RecG subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bsu:BSU00550 transcription-repair coupling factor (superfamily II helicase)%3B Acting on ATP%3B involved in cellular and subcellular movement gene gene3913 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03914 S100141_03915 S100141_03915 S100141_03915 3665947 3666483 + Stage V sporulation protein Activator%3B DNA-binding%3B Repressor%3B Sporulation%3B Transcription%3B Transcription regulation%3B Positive and negative transcriptional regulator of sigma G-dependent genes. May provide a mechanism of feedback control that is important for forespore development%3B Contains 1 SpoVT-AbrB domain%3B To B. subtilis AbrB and Abh gene gene3914 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03915 S100141_03916 S100141_03916 S100141_03916 3666697 3668289 + putative membrane protein YabM Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the polysaccharide synthase family gene gene3915 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03916 S100141_03917 S100141_03917 S100141_03917 3668279 3669748 + uncharacterized protein gene gene3916 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03917 S100141_03918 S100141_03918 S100141_03918 3669755 3670018 + uncharacterized protein RNA-binding%3B Contains 1 S4 RNA-binding domain gene gene3917 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03918 S100141_03919 S100141_03919 S100141_03919 3670095 3670403 + Spore protein YabP Membrane%3B Sporulation%3B Required for sporulation gene gene3918 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03919 S100141_03920 S100141_03920 S100141_03920 3670400 3671026 + Spore protein YabQ Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Required for sporulation. Plays an important role in cortex and coat formation gene gene3919 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03920 S100141_03921 S100141_03921 S100141_03921 3671043 3671420 + Cell division protein DivIC gene gene3920 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03921 S100141_03922 S100141_03922 S100141_03922 3671500 3671898 + uncharacterized protein Belongs to the peptidase U57 family%3B Contains 1 S1 motif domain gene gene3921 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03922 S100141_03923 S100141_03923 S100141_03923 3672049 3672122 + tRNA-Met tRNA gene3922 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03923 S100141_03924 S100141_03924 S100141_03924 3672133 3672204 + tRNA-Glu tRNA gene3923 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03924 S100141_03925 S100141_03925 S100141_03925 3672414 3674903 + Protein-serine/threonine phosphatase Cell membrane%3B Hydrolase%3B Membrane%3B Protein phosphatase%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Normally needed for pro-sigma E processing during sporulation but can be bypassed in vegetative cells. Activates SpoIIAA by dephosphorylation. Contains 1 PPM-type phosphatase domain%3B KEGG: bsu:BSU00640 stage II sporulation protein E gene gene3924 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03925 S100141_03926 S100141_03926 S100141_03926 3674980 3675717 + uncharacterized protein gene gene3925 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03926 S100141_03927 S100141_03927 S100141_03927 3675686 3676600 + Non-specific serine/threonine protein kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Serine/threonine-protein kinase%3B Transferase%3B Belongs to the protein kinase superfamily. Ser/Thr protein kinase family%3B Contains 1 protein kinase domain%3B KEGG: bli:BL00504 serine/threonine protein kinase%2C bacterial gene gene3926 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03927 S100141_03928 S100141_03928 tilS tilS 3676822 3678252 + tRNA(Ile)-lysidine synthetase ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B tRNA processing%3B Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU%2C in an ATP-dependent manner. Cytidine is converted to lysidine%2C thus changing the amino acid specificity of the tRNA from methionine to isoleucine%3B Belongs to the tRNA(Ile)-lysidine synthase family%3B KEGG: bli:BL00503 tRNA(Ile)-lysidine synthase gene gene3927 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03928 S100141_03929 S100141_03929 hprT hprT 3678236 3678775 + Hypoxanthine phosphoribosyltransferase Cytoplasm%3B Glycosyltransferase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Purine salvage%3B Transferase%3B Belongs to the purine/pyrimidine phosphoribosyltransferase family%3B KEGG: bli:BL05003 hypoxanthine phosphoribosyltransferase gene gene3928 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03929 S100141_03930 S100141_03930 ftsH ftsH 3678872 3679102 + ATP-dependent zinc metalloprotease FtsH ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Metal-binding%3B Metalloprotease%3B Nucleotide-binding%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Zinc%3B Acts as a processive%2C ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins%3B In the central sectio%3B belongs to the AAA ATPase family%3B In the C-terminal sectio%3B belongs to the peptidase M41 family%3B KEGG: bsu:BSU00690 cell division protease FtsH%3B Metalloendopeptidases gene gene3929 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03930 S100141_03931 S100141_03931 S100141_03931 3679291 3680790 + ATP-dependent zinc metalloprotease FtsH ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Metal-binding%3B Metalloprotease%3B Nucleotide-binding%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Zinc%3B Acts as a processive%2C ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins%3B In the central sectio%3B belongs to the AAA ATPase family%3B In the C-terminal sectio%3B belongs to the peptidase M41 family%3B KEGG: eco:b3178 cell division protease FtsH%3B Metalloendopeptidases gene gene3930 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03931 S100141_03932 S100141_03932 coaX coaX 3680993 3681769 + Pantothenate kinase ATP-binding%3B Coenzyme A biosynthesis%3B Cytoplasm%3B Kinase%3B Metal-binding%3B Nucleotide-binding%3B Potassium%3B Transferase%3B Catalyzes the phosphorylation of pantothenate (Pan)%2C the first step in CoA biosynthesis%3B Belongs to the type III pantothenate kinase family%3B KEGG: gsu:GSU1934 type III pantothenate kinase gene gene3931 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03932 S100141_03933 S100141_03933 S100141_03933 3681781 3682650 + 33 kDa chaperonin Chaperone%3B Cytoplasm%3B Disulfide bond%3B Redox-active center%3B Zinc%3B Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress%3B Belongs to the HSP33 family gene gene3932 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03933 S100141_03934 S100141_03934 S100141_03934 3682703 3683593 + Peptidylprolyl isomerase Isomerase%3B Rotamase%3B Signal%3B Contains 1 PpiC domain%3B KEGG: baci:B1NLA3E_00340 foldase protein PrsA gene gene3933 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03934 S100141_03935 S100141_03935 S100141_03935 3683669 3684592 + Cysteine synthase Amino-acid biosynthesis%3B Cysteine biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Catalyzes the conversion of O-acetylserine to cysteine. Also acts as a sensor of cysteine availability in the signal transduction pathway modulating CymR activity. When cysteine is present%2C the pool of O-acetylserine (OAS) is low%2C which leads to the formation of a CymR-CysK complex and transcriptional repression of the CymR regulon occurs. In the absence of cysteine%2C the OAS pool is high and the CymR-CysK complex is mostly dissociated%2C leading to a faster dissociation of CymR from its DNA targets and the lifting of CymR-dependent repression%3B Belongs to the cysteine synthase/cystathionine beta- synthase family%3B KEGG: bsu:BSU00730 cysteine synthase A gene gene3934 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03935 S100141_03936 S100141_03936 pabB pabB 3684789 3686222 + Aminodeoxychorismate synthase Folate biosynthesis%3B Magnesium%3B Transferase%3B Part of a heterodimeric complex that catalyzes the two- step biosynthesis of 4-amino-4-deoxychorismate (ADC)%2C a precursor of p-aminobenzoate (PABA) and tetrahydrofolate. In the first step%2C a glutamine amidotransferase (PabA) generates ammonia as a substrate that%2C along with chorismate%2C is used in the second step%2C catalyzed by aminodeoxychorismate synthase (PabB) to produce ADC%3B Belongs to the anthranilate synthase component I family%3B KEGG: bld:BLi00090 para-aminobenzoate synthetase component I%3B overlaps another CDS with the same product name gene gene3935 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03936 S100141_03937 S100141_03937 pabA pabA 3686219 3686803 + Aminodeoxychorismate synthase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Folate biosynthesis%3B Glutamine amidotransferase%3B Lyase%3B Transferase%3B Tryptophan biosynthesis%3B Part of a heterodimeric complex that catalyzes the two- step biosynthesis of 4-amino-4-deoxychorismate (ADC)%2C a precursor of p-aminobenzoate (PABA) and tetrahydrofolate. In the first step%2C a glutamine amidotransferase (PabA) generates ammonia as a substrate that%2C along with chorismate%2C is used in the second step%2C catalyzed by aminodeoxychorismate synthase (PabB) to produce ADC. PabA converts glutamine into glutamate only in the presence of stoichiometric amounts of PabB. Also involved in the biosynthesis of anthranilate%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: eco:b3360 para-aminobenzoate synthetase component II%3B overlaps another CDS with the same product name gene gene3936 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03937 S100141_03938 S100141_03938 S100141_03938 3686800 3687660 + Branched-chain-amino-acid transaminase Amino-acid biosynthesis%3B Aminotransferase%3B Branched-chain amino acid biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Acts on leucine%2C isoleucine and valine%3B Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: eca:ECA2971 branched-chain amino acid aminotransferase gene gene3937 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03938 S100141_03939 S100141_03939 folP folP 3687673 3688530 + Dihydropteroate synthase Folate biosynthesis%3B Magnesium%3B Metal-binding%3B Transferase%3B Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7%2C8-dihydropterin diphosphate (DHPt-PP) to form 7%2C8-dihydropteroate (H2Pte)%2C the immediate precursor of folate derivatives%3B Belongs to the DHPS family%3B Contains 1 pterin-binding domain%3B KEGG: bli:BL00861 dihydropteroate synthase gene gene3938 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03939 S100141_03940 S100141_03940 folB folB 3688502 3688885 + Dihydroneopterin aldolase Folate biosynthesis%3B Lyase%3B Catalyzes the conversion of 7%2C8-dihydroneopterin to 6- hydroxymethyl-7%2C8-dihydropterin%3B Belongs to the DHNA family%3B KEGG: bli:BL00862 dihydroneopterin aldolase gene gene3939 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03940 S100141_03941 S100141_03941 folK folK 3688882 3689382 + 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase ATP-binding%3B Folate biosynthesis%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the HPPK family%3B KEGG: bli:BL05004 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase gene gene3940 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03941 S100141_03942 S100141_03942 S100141_03942 3689334 3689543 + putative HTH-type transcriptional regulator YazB DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene3941 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03942 S100141_03943 S100141_03943 dusB dusB 3689560 3690561 + putative tRNA-dihydrouridine synthase Flavoprotein%3B FMN%3B NADP%3B Oxidoreductase%3B RNA-binding%3B tRNA processing%3B tRNA-binding%3B Catalyzes the synthesis of 5%2C6-dihydrouridine (D)%2C a modified base found in the D-loop of most tRNAs%2C via the reduction of the C5-C6 double bond in target uridines%3B Belongs to the Dus family%3B KEGG: rpo:MA1_00045 tRNA-dihydrouridine synthase B%3B Oxidoreductases gene gene3942 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03943 S100141_03944 S100141_03944 karS karS 3690643 3692145 + Lysine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: blh:BaLi_c00980 lysyl-tRNA synthetase%2C class II gene gene3943 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03944 S100141_03945 S100141_03945 S100141_03945 3692443 3693992 + 16S ribosomal RNA rRNA gene3944 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03945 S100141_03946 S100141_03946 S100141_03946 3694167 3697097 + 23S ribosomal RNA rRNA gene3945 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03946 S100141_03947 S100141_03947 S100141_03947 3697230 3697345 + 5S ribosomal RNA rRNA gene3946 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03947 S100141_03948 S100141_03948 S100141_03948 3697366 3697441 + tRNA-Val tRNA gene3947 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03948 S100141_03949 S100141_03949 S100141_03949 3697463 3697538 + tRNA-Thr tRNA gene3948 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03949 S100141_03950 S100141_03950 S100141_03950 3697574 3697649 + tRNA-Lys tRNA gene3949 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03950 S100141_03951 S100141_03951 S100141_03951 3697656 3697738 + tRNA-Leu tRNA gene3950 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03951 S100141_03952 S100141_03952 S100141_03952 3697755 3697829 + tRNA-Gly tRNA gene3951 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03952 S100141_03953 S100141_03953 S100141_03953 3697839 3697924 + tRNA-Leu tRNA gene3952 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03953 S100141_03954 S100141_03954 S100141_03954 3697934 3698010 + tRNA-Arg tRNA gene3953 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03954 S100141_03955 S100141_03955 S100141_03955 3698021 3698097 + tRNA-Pro tRNA gene3954 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03955 S100141_03956 S100141_03956 S100141_03956 3698104 3698179 + tRNA-Ala tRNA gene3955 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03956 S100141_03957 S100141_03957 S100141_03957 3698336 3699885 + 16S ribosomal RNA rRNA gene3956 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03957 S100141_03958 S100141_03958 S100141_03958 3700060 3702990 + 23S ribosomal RNA rRNA gene3957 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03958 S100141_03959 S100141_03959 S100141_03959 3703123 3703238 + 5S ribosomal RNA rRNA gene3958 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03959 S100141_03960 S100141_03960 S100141_03960 3703415 3703879 + Transcriptional regulator CtsR DNA-binding%3B Phosphoprotein%3B Repressor%3B Stress response%3B Transcription%3B Transcription regulation%3B Controls the expression of the cellular protein quality control genes clpC%2C clpE and clpP%2C as well as mcsA and mcsB. Acts as a repressor of these class III stress genes by binding to a directly repeated heptanucleotide operator sequence (A/GGTCAAA NAN A/GGTCAAA). After heat shock%2C CtsR is degraded by the ClpCP and ClpEP proteolytic systems%2C ensuring the derepression of clpE%2C clpP and the clpC operon. CtsR negatively autoregulates its own synthesis%3B Belongs to the CtsR family gene gene3959 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03960 S100141_03961 S100141_03961 S100141_03961 3704017 3704448 + Protein-arginine kinase activator protein Phosphoprotein%3B Activates the phosphorylation activity of the protein- arginine kinase McsB. Is required for the delocalization of competence proteins from the cell poles%3B Contains 1 UVR domain gene gene3960 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03961 S100141_03962 S100141_03962 mcsB mcsB 3704448 3705539 + Protein arginine kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes%2C such as protein homeostasis%2C motility%2C competence%2C and stringent and stress responses%2C by regulating gene expression and protein activity%3B Belongs to the ATP:guanido phosphotransferase family%3B Contains 1 phosphagen kinase C-terminal domain%3B KEGG: bli:BL03260 protein arginine kinase gene gene3961 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03962 S100141_03963 S100141_03963 S100141_03963 3705536 3707968 + Chaperone protein ClpB ATP-binding%3B Chaperone%3B Coiled coil%3B Cytoplasm%3B Nucleotide-binding%3B Repeat%3B Stress response%3B Part of a stress-induced multi-chaperone system%2C it is involved in the recovery of the cell from heat-induced damage%2C in cooperation with DnaK%2C DnaJ and GrpE. Acts before DnaK%2C in the processing of protein aggregates. Protein binding stimulates the ATPase activit%3B ATP hydrolysis unfolds the denatured protein aggregates%2C which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates%2C contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity)%3B Belongs to the ClpA/ClpB family%3B Contains 1 UVR domain gene gene3962 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03963 S100141_03964 S100141_03964 S100141_03964 3708048 3709427 + DNA repair protein RadA like protein ATP-binding%3B DNA damage%3B DNA repair%3B DNA-binding%3B Metal-binding%3B Nucleotide-binding%3B Zinc%3B Zinc-finger%3B May play a role in the repair of endogenous alkylation damage%3B Belongs to the RecA family. RadA subfamily gene gene3963 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03964 S100141_03965 S100141_03965 disA disA 3709431 3710507 + Diadenylate cyclase ATP-binding%3B DNA damage%3B DNA repair%3B DNA-binding%3B Magnesium%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase%3B Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation%2C searching for lesions. When a lesion is present%2C DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation%3B Has also diadenylate cyclase activity%2C catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome%2C operates as a positive signal that advances sporulatio%3B upon encountering a lesion%2C the DisA focus arrests at the damaged site and halts c-di- AMP synthesis%3B Belongs to the DisA family%3B KEGG: bli:BL03263 diadenylate cyclase gene gene3964 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03965 S100141_03966 S100141_03966 S100141_03966 3710639 3711727 + putative PIN and TRAM-domain containing protein YacL Hydrolase%3B Magnesium%3B Metal-binding%3B Nuclease%3B An RNase%3B Belongs to the ycf81 family%3B In the central sectio%3B belongs to the PINc/VapC protein family%3B Contains 1 PINc domain%3B Contains 1 TRAM domain gene gene3965 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03966 S100141_03967 S100141_03967 ispD ispD 3711744 3712439 + 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Isoprene biosynthesis%3B Nucleotidyltransferase%3B Transferase%3B Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)%3B Belongs to the IspD family%3B KEGG: bsu:BSU00900 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase gene gene3966 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03967 S100141_03968 S100141_03968 ispF ispF 3712432 3712908 + 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate synthase Isoprene biosynthesis%3B Lyase%3B Metal-binding%3B Multifunctional enzyme%3B Nucleotidyltransferase%3B Transferase%3B Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD)%2C and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2%2C4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)%3B In the N-terminal sectio%3B belongs to the IspD family%3B In the C-terminal sectio%3B belongs to the IspF family%3B KEGG: ctu:CTU_33200 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate synthase gene gene3967 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03968 S100141_03969 S100141_03969 gltX gltX 3712990 3714447 + Glutamate--tRNA(Gln) ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)%3B Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: bsu:BSU00920 nondiscriminating glutamyl-tRNA synthetase gene gene3968 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03969 S100141_03970 S100141_03970 S100141_03970 3714749 3715399 + Serine O-acetyltransferase Acyltransferase%3B Amino-acid biosynthesis%3B Cysteine biosynthesis%3B Cytoplasm%3B Repeat%3B Transferase%3B Catalyzes the acetylation of serine by acetyl-CoA to produce O-acetylserine (OAS)%3B Belongs to the transferase hexapeptide repeat family%3B KEGG: cha:CHAB381_0927 serine O-acetyltransferase gene gene3969 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03970 S100141_03971 S100141_03971 carS carS 3715396 3716799 + Cysteine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B Zinc%3B Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: fau:Fraau_2118 cysteinyl-tRNA synthetase gene gene3970 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03971 S100141_03972 S100141_03972 S100141_03972 3716802 3717218 + Mini-ribonuclease Cytoplasm%3B Endonuclease%3B Hydrolase%3B Magnesium%3B Nuclease%3B Ribosome biogenesis%3B RNA-binding%3B rRNA processing%3B rRNA-binding%3B Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc%3B Rnc processes 30S rRNA into smaller rRNA precursors. Cleaves more efficiently on assembled 50S ribosomal subunits. Cleavage is strongly stimulated by ribosomal protein L3 (RplC%3B 20-30%25 DMSO can replace RplC%2C suggesting RplC may alter rRNA conformation%3B Belongs to the MrnC RNase family%3B KEGG: bli:BL03270 ribonuclease III family protein%3B Endoribonucleases producing 5'-phosphomonoesters gene gene3971 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03972 S100141_03973 S100141_03973 rlmB rlmB 3717215 3717964 + 23S rRNA (guanosine(2251)-2'-O)-methyltransferase Methyltransferase%3B Transferase%3B Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family%3B KEGG: bsu:BSU00960 23S rRNA (guanosine2251-2'-O)-methyltransferase gene gene3972 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03973 S100141_03974 S100141_03974 S100141_03974 3717970 3718482 + uncharacterized protein gene gene3973 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03974 S100141_03975 S100141_03975 S100141_03975 3718546 3719217 + RNA polymerase sigma-H factor DNA-binding%3B Sigma factor%3B Sporulation%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in the transition to post-exponential phase in the beginning of sporulation. Belongs to the sigma-70 factor family gene gene3974 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03975 S100141_03976 S100141_03976 S100141_03976 3719485 3719664 + Protein translocase subunit SecE Cell membrane%3B Membrane%3B Protein transport%3B Translocation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation%3B Belongs to the SecE/SEC61-gamma family gene gene3975 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03976 S100141_03977 S100141_03977 S100141_03977 3719836 3720375 + Transcription termination/antitermination protein NusG Transcription%3B Transcription antitermination%3B Transcription regulation%3B Transcription termination%3B Participates in transcription elongation%2C termination and antitermination. In the absence of Rho%2C increases the rate of transcription elongation by the RNA polymerase (RNAP)%2C probably by partially suppressing pausing. In the presence of Rho%2C modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination%3B Belongs to the NusG family%3B Contains 1 KOW domain gene gene3976 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03977 S100141_03978 S100141_03978 S100141_03978 3720545 3720970 + 50S ribosomal protein L11-1 Methylation%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors%3B Belongs to the ribosomal protein L11P family gene gene3977 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03978 S100141_03979 S100141_03979 S100141_03979 3721072 3721770 + 50S ribosomal protein L1 Repressor%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Translation regulation%3B tRNA-binding%3B Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome%2C and is involved in E site tRNA release%3B Protein L1 is also a translational repressor protein%2C it controls the translation of the L11 operon by binding to its mRNA%3B Belongs to the ribosomal protein L1P family gene gene3978 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03979 S100141_03980 S100141_03980 S100141_03980 3722032 3722532 + 50S ribosomal protein L10 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Forms part of the ribosomal stalk%2C playing a central role in the interaction of the ribosome with GTP-bound translation factors%3B Belongs to the ribosomal protein L10P family gene gene3979 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03980 S100141_03981 S100141_03981 S100141_03981 3722577 3722948 + 50S ribosomal protein L7/L12 Ribonucleoprotein%3B Ribosomal protein%3B Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation%3B Belongs to the ribosomal protein L7/L12P family gene gene3980 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03981 S100141_03982 S100141_03982 rsmC rsmC 3723088 3723693 + 16S rRNA (guanine(1207)-N(2))-methyltransferase Methyltransferase%3B Transferase%3B Belongs to the methyltransferase superfamily%3B KEGG: bsu:BSU01060 16S rRNA (guanine1207-N2)-methyltransferase gene gene3981 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03982 S100141_03983 S100141_03983 rpoB rpoB 3723944 3727525 + DNA-directed RNA polymerase DNA-directed RNA polymerase%3B Nucleotidyltransferase%3B Transcription%3B Transferase%3B DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B Belongs to the RNA polymerase beta chain family%3B KEGG: bsu:BSU01070 DNA-directed RNA polymerase subunit beta gene gene3982 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03983 S100141_03984 S100141_03984 rpoC rpoC 3727585 3731184 + DNA-directed RNA polymerase DNA-directed RNA polymerase%3B Nucleotidyltransferase%3B Transcription%3B Transferase%3B DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B Belongs to the RNA polymerase beta' chain family%3B KEGG: ssdc:SSDC_00130 DNA-directed RNA polymerase subunit beta' gene gene3983 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03984 S100141_03985 S100141_03985 S100141_03985 3731304 3731552 + Putative ribosomal protein L7Ae-like Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L7Ae family gene gene3984 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03985 S100141_03986 S100141_03986 S100141_03986 3731657 3732073 + 30S ribosomal protein S12 Methylation%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B tRNA-binding%3B With S4 and S5 plays an important role in translational accuracy%3B Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits%2C it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8%2C S12 and S17 appears to hold together the shoulder and platform of the 30S subunit%3B Belongs to the ribosomal protein S12P family gene gene3985 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03986 S100141_03987 S100141_03987 S100141_03987 3732239 3732709 + 30S ribosomal protein S7 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B tRNA-binding%3B One of the primary rRNA binding proteins%2C it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center%2C probably blocks exit of the E-site tRNA%3B Belongs to the ribosomal protein S7P family gene gene3986 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03987 S100141_03988 S100141_03988 S100141_03988 3732759 3734837 + Elongation factor G Cytoplasm%3B Elongation factor%3B GTP-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step%2C the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites%2C respectively. Catalyzes the coordinated movement of the two tRNA molecules%2C the mRNA and conformational changes in the ribosome%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene3987 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03988 S100141_03989 S100141_03989 S100141_03989 3734957 3736147 + Elongation factor Tu-A Cytoplasm%3B Elongation factor%3B GTP-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene3988 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03989 S100141_03990 S100141_03990 S100141_03990 3736469 3736777 + 30S ribosomal protein S10%2C chloroplastic Chloroplast%3B Plastid%3B Ribonucleoprotein%3B Ribosomal protein%3B Involved in the binding of tRNA to the ribosomes%3B Belongs to the ribosomal protein S10P family gene gene3989 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03990 S100141_03991 S100141_03991 S100141_03991 3736816 3737445 + 50S ribosomal protein L3 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B One of the primary rRNA binding proteins%2C it binds directly near the 3'-end of the 23S rRNA%2C where it nucleates assembly of the 50S subunit%3B Belongs to the ribosomal protein L3P family gene gene3990 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03991 S100141_03992 S100141_03992 S100141_03992 3737473 3738096 + 50S ribosomal protein L4 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B One of the primary rRNA binding proteins%2C this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome%3B Forms part of the polypeptide exit tunnel%3B Belongs to the ribosomal protein L4P family gene gene3991 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03992 S100141_03993 S100141_03993 S100141_03993 3738096 3738383 + 50S ribosomal protein L23 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome%3B Belongs to the ribosomal protein L23P family gene gene3992 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03993 S100141_03994 S100141_03994 S100141_03994 3738415 3739248 + 50S ribosomal protein L2 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome%2C for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activit%3B this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome%3B Belongs to the ribosomal protein L2P family gene gene3993 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03994 S100141_03995 S100141_03995 S100141_03995 3739306 3739584 + 30S ribosomal protein S19%2C chloroplastic Chloroplast%3B Plastid%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA%3B Belongs to the ribosomal protein S19P family gene gene3994 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03995 S100141_03996 S100141_03996 S100141_03996 3739602 3739946 + 50S ribosomal protein L22 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B This protein binds specifically to 23S rRN%3B its binding is stimulated by other ribosomal proteins%2C e. g. L4%2C L17%2C and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)%3B The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit%2C while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome%3B Belongs to the ribosomal protein L22P family gene gene3995 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03996 S100141_03997 S100141_03997 S100141_03997 3739950 3740606 + 30S ribosomal protein S3%2C chloroplastic Chloroplast%3B Plastid%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Belongs to the ribosomal protein S3P family%3B Contains 1 KH type-2 domain gene gene3996 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03997 S100141_03998 S100141_03998 S100141_03998 3740608 3741042 + 50S ribosomal protein L16%2C plastid Plastid%3B Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L16P family gene gene3997 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03998 S100141_03999 S100141_03999 S100141_03999 3741032 3741232 + 50S ribosomal protein L29 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L29P family gene gene3998 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_03999 S100141_04000 S100141_04000 S100141_04000 3741257 3741520 + 30S ribosomal protein S17 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B One of the primary rRNA binding proteins%2C it binds specifically to the 5'-end of 16S ribosomal RNA%3B Belongs to the ribosomal protein S17P family gene gene3999 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04000 S100141_04001 S100141_04001 S100141_04001 3741561 3741929 + 50S ribosomal protein L14 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome%3B Belongs to the ribosomal protein L14P family gene gene4000 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04001 S100141_04002 S100141_04002 S100141_04002 3741965 3742276 + 50S ribosomal protein L24 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B One of two assembly initiator proteins%2C it binds directly to the 5'-end of the 23S rRNA%2C where it nucleates assembly of the 50S subunit%3B One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit%3B Belongs to the ribosomal protein L24P family gene gene4001 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04002 S100141_04003 S100141_04003 S100141_04003 3742302 3742841 + 50S ribosomal protein L5 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B tRNA-binding%3B This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit%2C where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b)%2C connecting the 2 subunit%3B this bridge is implicated in subunit movement. Contacts the P site tRN%3B the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs%3B Belongs to the ribosomal protein L5P family gene gene4002 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04003 S100141_04004 S100141_04004 S100141_04004 3742864 3743049 + 30S ribosomal protein S14 type Z Metal-binding%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Zinc%3B Binds 16S rRNA%2C required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site%3B Belongs to the ribosomal protein S14P family. Zinc- binding S14P subfamily gene gene4003 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04004 S100141_04005 S100141_04005 S100141_04005 3743081 3743479 + 30S ribosomal protein S8 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B One of the primary rRNA binding proteins%2C it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit%3B Belongs to the ribosomal protein S8P family gene gene4004 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04005 S100141_04006 S100141_04006 S100141_04006 3743509 3744045 + 50S ribosomal protein L6%2C cyanelle Cyanelle%3B Plastid%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Binds 23S rRNA%3B Belongs to the ribosomal protein L6P family gene gene4005 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04006 S100141_04007 S100141_04007 S100141_04007 3744077 3744439 + 50S ribosomal protein L18 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit%2C where it forms part of the central protuberance%3B Belongs to the ribosomal protein L18P family gene gene4006 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04007 S100141_04008 S100141_04008 S100141_04008 3744458 3744964 + 30S ribosomal protein Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B With S4 and S12 plays an important role in translational accuracy%3B Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body%3B Belongs to the ribosomal protein S5P family%3B Contains 1 S5 DRBM domain gene gene4007 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04008 S100141_04009 S100141_04009 S100141_04009 3744978 3745157 + 50S ribosomal protein L30 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L30P family gene gene4008 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04009 S100141_04010 S100141_04010 S100141_04010 3745188 3745628 + 50S ribosomal protein L15 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Binds to the 23S rRNA%3B Belongs to the ribosomal protein L15P family gene gene4009 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04010 S100141_04011 S100141_04011 S100141_04011 3745630 3746925 + Protein translocase subunit SecY Cell membrane%3B Membrane%3B Protein transport%3B Translocation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7%2C and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently%3B Belongs to the SecY/SEC61-alpha family gene gene4010 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04011 S100141_04012 S100141_04012 S100141_04012 3746979 3747632 + Adenylate kinase ATP-binding%3B Cytoplasm%3B Kinase%3B Metal-binding%3B Nucleotide biosynthesis%3B Nucleotide-binding%3B Transferase%3B Zinc%3B Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism%3B Belongs to the adenylate kinase family%3B KEGG: cbu:CBU_0454 adenylate kinase gene gene4011 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04012 S100141_04013 S100141_04013 S100141_04013 3747629 3748375 + Methionyl aminopeptidase Aminopeptidase%3B Cytoplasm%3B Hydrolase%3B Metal-binding%3B Protease%3B Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-%2C Cys%2C Gly%2C Pro%2C Ser%2C Thr%2C or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed%3B Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily%3B KEGG: bsu:BSU01380 methionyl aminopeptidase gene gene4012 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04013 S100141_04014 S100141_04014 S100141_04014 3748386 3748715 + Putative ribosome-binding protein YbzG gene gene4013 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04014 S100141_04015 S100141_04015 S100141_04015 3748693 3748911 + Translation initiation factor IF-1 Cytoplasm%3B Initiation factor%3B Protein biosynthesis%3B RNA-binding%3B rRNA-binding%3B One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection%2C yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1%2C IF-2 and IF-3 are released leaving the mature 70S translation initation complex%3B Belongs to the IF-1 family%3B Contains 1 S1-like domain gene gene4014 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04015 S100141_04016 S100141_04016 S100141_04016 3748945 3749058 + 50S ribosomal protein L36%2C chloroplastic Chloroplast%3B Plastid%3B Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L36P family gene gene4015 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04016 S100141_04017 S100141_04017 S100141_04017 3749081 3749446 + Cyanelle 30S ribosomal protein S13 Cyanelle%3B Plastid%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Located at the top of the head of the 30S subunit%2C it contacts several helices of the 16S rRNA%3B Belongs to the ribosomal protein S13P family gene gene4016 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04017 S100141_04018 S100141_04018 S100141_04018 3749467 3749862 + 30S ribosomal protein S11 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Located on the platform of the 30S subunit%2C it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome%3B Belongs to the ribosomal protein S11P family gene gene4017 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04018 S100141_04019 S100141_04019 rpoA rpoA 3750037 3750981 + DNA-directed RNA polymerase DNA-directed RNA polymerase%3B Nucleotidyltransferase%3B Transcription%3B Transferase%3B DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B Belongs to the RNA polymerase alpha chain family%3B KEGG: bsu:BSU01430 DNA-directed RNA polymerase subunit alpha gene gene4018 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04019 S100141_04020 S100141_04020 S100141_04020 3751059 3751421 + 50S ribosomal protein L17 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L17P family gene gene4019 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04020 S100141_04021 S100141_04021 S100141_04021 3751563 3752408 + Energy-coupling factor transporter ATP-binding protein EcfA1 ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the ABC transporter superfamily. Energy- coupling factor EcfA family%3B Contains 1 ABC transporter domain%3B KEGG: bli:BL01023 energy-coupling factor transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene4020 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04021 S100141_04022 S100141_04022 S100141_04022 3752384 3753253 + Energy-coupling factor transporter ATP-binding protein EcfA2 ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the ABC transporter superfamily. Energy- coupling factor EcfA family%3B Contains 1 ABC transporter domain gene gene4021 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04022 S100141_04023 S100141_04023 S100141_04023 3753250 3754047 + Energy-coupling factor transporter transmembrane protein EcfT Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the energy-coupling factor EcfT family gene gene4022 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04023 S100141_04024 S100141_04024 truA truA 3754058 3754801 + tRNA pseudouridine(38-40) synthase Isomerase%3B tRNA processing%3B Formation of pseudouridine at positions 38%2C 39 and 40 in the anticodon stem and loop of transfer RNAs%3B Belongs to the tRNA pseudouridine synthase TruA family%3B KEGG: bsu:BSU01480 tRNA pseudouridine38-40 synthase gene gene4023 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04024 S100141_04025 S100141_04025 S100141_04025 3754962 3755399 + 50S ribosomal protein L13 Ribonucleoprotein%3B Ribosomal protein%3B This protein is one of the early assembly proteins of the 50S ribosomal subunit%2C although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly%3B Belongs to the ribosomal protein L13P family gene gene4024 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04025 S100141_04026 S100141_04026 S100141_04026 3755420 3755812 + 30S ribosomal protein S9 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein S9P family gene gene4025 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04026 S100141_04027 S100141_04027 S100141_04027 3755863 3756321 - uncharacterized protein Metal-binding%3B Belongs to the DinB family gene gene4026 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04027 S100141_04028 S100141_04028 S100141_04028 3756433 3756876 + uncharacterized protein gene gene4027 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04028 S100141_04029 S100141_04029 S100141_04029 3756969 3757682 + N-acetylmuramoyl-L-alanine amidase Cell wall biogenesis/degradation%3B Hydrolase%3B Secreted%3B Signal%3B Cleaves the peptide side chain from the N-acetylmuramic acid residues in peptidoglycan. This is a step in the formation of muramic delta-lactam residues in spore cortex%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B KEGG: bsu:BSU01530 N-acetylmuramoyl-L-alanine amidase gene gene4028 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04029 S100141_04030 S100141_04030 S100141_04030 3757723 3758829 + Iron-sulfur cluster carrier protein ATP-binding%3B Hydrolase%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Nucleotide-binding%3B Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP%3B Negatively regulates the expression of hpr/scoC. The effect on hpr/scoC may be indirect%3B Belongs to the Mrp/NBP35 ATP-binding proteins family gene gene4029 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04030 S100141_04031 S100141_04031 S100141_04031 3758883 3759464 - Spore germination protein GerD Cell membrane%3B Germination%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal. gene gene4030 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04031 S100141_04032 S100141_04032 S100141_04032 3759579 3760178 + KinB-signaling pathway activation protein Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Involved in the activation of the KinB signaling pathway of sporulation gene gene4031 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04032 S100141_04033 S100141_04033 S100141_04033 3760187 3760951 - putative polysaccharide deacetylase PdaB Hydrolase%3B Signal%3B Sporulation%3B Necessary to maintain spores after the late stage of sporulation. Might be involved in cortex formation%3B Belongs to the polysaccharide deacetylase family%3B KEGG: css:Cst_c05460 peptidoglycan-N-acetylmuramic acid deacetylase%3B In linear amides gene gene4032 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04033 S100141_04034 S100141_04034 S100141_04034 3761291 3762841 + 16S ribosomal RNA rRNA gene4033 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04034 S100141_04035 S100141_04035 S100141_04035 3763016 3765946 + 23S ribosomal RNA rRNA gene4034 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04035 S100141_04036 S100141_04036 S100141_04036 3766079 3766194 + 5S ribosomal RNA rRNA gene4035 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04036 S100141_04037 S100141_04037 S100141_04037 3766237 3766311 + tRNA-Asn tRNA gene4036 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04037 S100141_04038 S100141_04038 S100141_04038 3766314 3766386 + tRNA-Thr tRNA gene4037 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04038 S100141_04039 S100141_04039 S100141_04039 3766510 3766677 - hypothetical protein gene gene4038 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04039 S100141_04040 S100141_04040 S100141_04040 3766771 3767940 - Putative penicillin-binding protein PbpX Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Belongs to the beta-lactamase family gene gene4039 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04040 S100141_04041 S100141_04041 S100141_04041 3768115 3768336 + hypothetical protein gene gene4040 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04041 S100141_04042 S100141_04042 S100141_04042 3768448 3769425 + Tagaturonate reductase Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B KEGG: sbu:SpiBuddy_3010 tagaturonate reductase gene gene4041 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04042 S100141_04043 S100141_04043 S100141_04043 3769460 3769873 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4042 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04043 S100141_04044 S100141_04044 phzF phzF 3769889 3770758 - Trans-2%2C3-dihydro-3-hydroxyanthranilate isomerase Antibiotic biosynthesis%3B Isomerase%3B Isomerase that catalyzes the condensation of two molecules of trans-2%2C3-dihydro-3-hydroxyanthranilic acid (DHHA) into the phenazine ring system. The final product is not yet known (By similarity)%3B Belongs to the PhzF family%3B KEGG: hdn:Hden_2074 trans-2%2C3-dihydro-3-hydroxyanthranilate isomerase gene gene4043 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04044 S100141_04045 S100141_04045 nagZ nagZ 3770864 3772093 - Beta-N-acetylhexosaminidase Signal%3B KEGG: hhd:HBHAL_2473 beta-N-acetylhexosaminidase%3B overlaps another CDS with the same product name gene gene4044 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04045 S100141_04046 S100141_04046 S100141_04046 3772093 3774024 - Beta-N-acetylhexosaminidase Cell membrane%3B Cell shape%3B Cell wall%3B Cell wall biogenesis/degradation%3B Glycosidase%3B Hydrolase%3B Lipoprotein%3B Membrane%3B Palmitate%3B Peptidoglycan synthesis%3B Secreted%3B Signal%3B Cleaves muropeptides%2C but not peptidoglycan%3B Belongs to the glycosyl hydrolase 3 family%3B KEGG: bli:BL02716 beta-N-acetylhexosaminidase%3B overlaps another CDS with the same product name gene gene4045 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04046 S100141_04047 S100141_04047 S100141_04047 3774040 3775386 - N-acetylmuramoyl-L-alanine amidase Signal%3B Belongs to the UPF0214 family%3B KEGG: pat:Patl_4160 N-acetylmuramoyl-L-alanine amidase gene gene4046 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04047 S100141_04048 S100141_04048 S100141_04048 3775454 3776821 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell inner membrane%3B Cell membrane%3B Kinase%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in arbutin%2C cellobiose%2C and salicin transport. Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bli:BL02718 PTS system%2C sucrose-specific IIB component gene gene4047 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04048 S100141_04049 S100141_04049 S100141_04049 3776848 3777696 - putative HTH-type transcriptional regulator YbbH DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH rpiR-type DNA-binding domain%3B Contains 1 SIS domain gene gene4048 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04049 S100141_04050 S100141_04050 S100141_04050 3777715 3778629 - N-acetylmuramic acid 6-phosphate etherase Carbohydrate metabolism%3B Lyase%3B Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate%2C producing GlcNAc 6- phosphate and D-lactate%3B Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily%3B Contains 1 SIS domain%3B KEGG: bli:BL02720 N-acetylmuramic acid 6-phosphate etherase gene gene4049 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04050 S100141_04051 S100141_04051 S100141_04051 3778804 3779256 - uncharacterized protein gene gene4050 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04051 S100141_04052 S100141_04052 S100141_04052 3779440 3779514 + tRNA-Glu tRNA gene4051 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04052 S100141_04053 S100141_04053 S100141_04053 3779665 3779740 + tRNA-Val tRNA gene4052 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04053 S100141_04054 S100141_04054 S100141_04054 3779799 3779871 + tRNA-Thr tRNA gene4053 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04054 S100141_04055 S100141_04055 S100141_04055 3779880 3779964 + tRNA-Tyr tRNA gene4054 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04055 S100141_04056 S100141_04056 S100141_04056 3779969 3780040 + tRNA-Gln tRNA gene4055 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04056 S100141_04057 S100141_04057 rocF rocF 3780166 3781080 + Arginase Arginine metabolism%3B Hydrolase%3B Manganese%3B Metal-binding%3B Belongs to the arginase family%3B KEGG: bli:BL02698 arginase gene gene4056 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04057 S100141_04058 S100141_04058 S100141_04058 3781306 3781869 + ECF RNA polymerase sigma factor SigW DNA-binding%3B Sigma factor%3B Stress response%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma factors are held in an inactive form by a cognate anti-sigma factor (RsiW for this protein) until released by regulated membrane proteolysis. Sigma-W controls genes involved in transport processes and detoxification%3B Belongs to the sigma-70 factor family. ECF subfamily gene gene4057 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04058 S100141_04059 S100141_04059 S100141_04059 3781913 3782503 + Anti-sigma-W factor RsiW Membrane%3B Metal-binding%3B Transmembrane%3B Transmembrane helix%3B Zinc%3B Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW%2C and its proteolytic destruction to sigma-W activation (By similarity)%3B Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family gene gene4058 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04059 S100141_04060 S100141_04060 dacA dacA 3782669 3783490 + Diadenylate cyclase Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B KEGG: bsu:BSU01750 diadenylate cyclase gene gene4059 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04060 S100141_04061 S100141_04061 S100141_04061 3783483 3784799 + YbbR-like domain-containing protein YbbR Repeat%3B Signal%3B Contains 4 YbbR-like domains gene gene4060 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04061 S100141_04062 S100141_04062 glmM glmM 3784820 3786166 + Phosphoglucosamine mutase Isomerase%3B Magnesium%3B Metal-binding%3B Phosphoprotein%3B Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate%3B Belongs to the phosphohexose mutase family%3B KEGG: scu:SCE1572_24625 phosphoglucosamine mutase gene gene4061 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04062 S100141_04063 S100141_04063 glmS glmS 3786608 3788410 + Glutamine--fructose-6-phosphate transaminase (isomerizing) Aminotransferase%3B Cytoplasm%3B Glutamine amidotransferase%3B Repeat%3B Transferase%3B Catalyzes the first step in hexosamine metabolism%2C converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source%3B Contains 1 glutamine amidotransferase type-2 domain%3B Contains 2 SIS domains%3B KEGG: alv:Alvin_0239 glucosamine--fructose-6-phosphate aminotransferase (isomerizing) gene gene4062 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04063 S100141_04064 S100141_04064 S100141_04064 3788601 3788924 + hypothetical protein gene gene4063 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04064 S100141_04065 S100141_04065 S100141_04065 3789067 3789675 - hypothetical protein gene gene4064 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04065 S100141_04066 S100141_04066 S100141_04066 3789656 3790537 - putative ABC transporter ATP-binding protein ATP-binding%3B Nucleotide-binding%3B Repeat%3B Transport%3B Belongs to the ABC transporter superfamily%3B Contains 2 ABC transporter domains gene gene4065 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04066 S100141_04067 S100141_04067 S100141_04067 3790537 3790914 - putative HTH-type transcriptional regulator YhdI Aminotransferase%3B DNA-binding%3B Pyridoxal phosphate%3B Transcription%3B Transcription regulation%3B Transferase%3B In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene4066 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04067 S100141_04068 S100141_04068 S100141_04068 3791095 3791397 + putative HTH-type transcriptional regulator YbzH DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH arsR-type DNA-binding domain gene gene4067 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04068 S100141_04069 S100141_04069 S100141_04069 3791542 3792714 + Putative multidrug resistance protein MdtD Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily. TCR/Tet family gene gene4068 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04069 S100141_04070 S100141_04070 S100141_04070 3792963 3793367 - hypothetical protein gene gene4069 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04070 S100141_04071 S100141_04071 abcA abcA 3793396 3795132 - Xenobiotic-transporting ATPase Antibiotic resistance%3B ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B An efflux transporter able to transport Hoechst 33342%2C ethidium bromide%2C doxorubicin and a number of other drugs in vitro into inside out vesicles. The endogenous substrate is unknown. It has been suggested that NBD dimerization induced by ATP-binding causes a large conformational change responsible for substrate translocation (PubMed:18215075). Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (Probable)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain%3B KEGG: bli:BL02726 ATP-binding cassette%2C subfamily B%2C bacterial AbcA/BmrA gene gene4070 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04071 S100141_04072 S100141_04072 S100141_04072 3795327 3795971 + uncharacterized protein gene gene4071 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04072 S100141_04073 S100141_04073 S100141_04073 3796045 3796464 + hypothetical protein gene gene4072 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04073 S100141_04074 S100141_04074 S100141_04074 3796539 3797063 + hypothetical protein gene gene4073 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04074 S100141_04075 S100141_04075 aadK aadK 3797172 3798041 + Aminoglycoside 6-adenylyltransferase Transferase%3B To E. faecalis AadE%3B KEGG: bsu:BSU26790 aminoglycoside 6-adenylyltransferase%3B Nucleotidyltransferases gene gene4074 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04075 S100141_04076 S100141_04076 S100141_04076 3798105 3799052 + hypothetical protein gene gene4075 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04076 S100141_04077 S100141_04077 S100141_04077 3799075 3799794 + (S)-2-haloacid dehalogenase Hydrolase%3B Belongs to the HAD-like hydrolase superfamily. YjjG family%3B KEGG: bli:BL02712 2-haloacid dehalogenase gene gene4076 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04077 S100141_04078 S100141_04078 S100141_04078 3800088 3801458 + putative transporter YbxG Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probable amino-acid or metabolite transport protein. Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene4077 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04078 S100141_04079 S100141_04079 S100141_04079 3801842 3803140 - Mg(2+)/citrate complex secondary transporter Cell membrane%3B Citrate utilization%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Proton motive force-driven secondary transporter that mediates the transport of citrate complexed to Mg(2+). Cotransports at least two protons per Mg(2+)-citrate complex. Can also transport citrate in complex with Ni(2+)%2C Mn(2+)%2C Co(2+)%2C and Zn(2+). Belongs to the CitM (TC 2. A. 11) transporter family gene gene4078 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04079 S100141_04080 S100141_04080 S100141_04080 3803344 3804303 - UPF0065 protein YflP Signal%3B Belongs to the UPF0065 (bug) family gene gene4079 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04080 S100141_04081 S100141_04081 S100141_04081 3804306 3804986 - putative C4-dicarboxylate response regulator DctR Activator%3B Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system DctS/DctR. Essential for expression of DctP (By similarity)%3B Contains 1 response regulatory domain gene gene4080 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04081 S100141_04082 S100141_04082 citS citS 3804983 3806599 - Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system CitT/CitS. Regulates the expression of the citM-yflN operon. Functions probably as a membrane-associated protein kinase that phosphorylates CitT in response to environmental citrate or Mg(2+)-citrate complex%3B Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bld:BLi00225 two-component system%2C CitB family%2C sensor histidine kinase CitS gene gene4081 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04082 S100141_04083 S100141_04083 S100141_04083 3807097 3807993 - HTH-type transcriptional activator AllS Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Positive regulator essential for the expression of allD operon. Binds to the allD promoter (By similarity)%3B Contains 1 HTH lysR-type DNA-binding domain gene gene4082 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04083 S100141_04084 S100141_04084 bacD bacD 3808116 3809333 + L-alanine--L-anticapsin ligase ATP-binding%3B Cobalt%3B Ligase%3B Magnesium%3B Manganese%3B Metal-binding%3B Nucleotide-binding%3B Catalyzes the synthesis of Arg-Xaa dipeptides in an ATP- dependent manner. Has strict specificity toward arginine as the N- terminal substrate%3B Contains 1 ATP-grasp domain%3B KEGG: bpu:BPUM_3423 L-alanine-L-anticapsin ligase gene gene4083 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04084 S100141_04085 S100141_04085 S100141_04085 3809407 3810543 + putative MFS-type transporter YdeE Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the major facilitator superfamily gene gene4084 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04085 S100141_04086 S100141_04086 S100141_04086 3810614 3810862 + Sigma-G-dependent sporulation-specific SASP protein Sporulation. gene gene4085 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04086 S100141_04087 S100141_04087 S100141_04087 3810879 3811070 + uncharacterized protein gene gene4086 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04087 S100141_04088 S100141_04088 S100141_04088 3811191 3811457 - uncharacterized protein Signal. gene gene4087 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04088 S100141_04089 S100141_04089 S100141_04089 3811515 3813572 - uncharacterized protein gene gene4088 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04089 S100141_04090 S100141_04090 S100141_04090 3813802 3814251 + SPBc2 prophage-derived putative transcriptional regulator YosT gene gene4089 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04090 S100141_04091 S100141_04091 S100141_04091 3814542 3814715 - Spermatoproteinis-associated protein Developmental protein%3B Differentiation%3B Phosphoprotein%3B Secreted%3B Spermatogenesis%3B May play a role in fertility regulation gene gene4090 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04091 S100141_04092 S100141_04092 S100141_04092 3815442 3816725 + putative MFS-type transporter YdeG Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene4091 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04092 S100141_04093 S100141_04093 chlM chlM 3816750 3817523 - Magnesium protoporphyrin IX methyltransferase KEGG: hmo:HM1_0689 magnesium-protoporphyrin O-methyltransferase gene gene4092 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04093 S100141_04094 S100141_04094 S100141_04094 3817691 3818563 + NAD(P)H dehydrogenase (quinone) NADP%3B Oxidoreductase%3B Quinone oxidoreductase that may play some additional role beyond quinone reduction. Potential redox sensor protein. Overexpression induces retardation of growth%3B Belongs to the NmrA-type oxidoreductase family%3B KEGG: pfe:PSF113_2585 NAD(P)H dehydrogenase (quinone) gene gene4093 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04094 S100141_04095 S100141_04095 S100141_04095 3818918 3819424 - hypothetical protein gene gene4094 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04095 S100141_04096 S100141_04096 S100141_04096 3819662 3821296 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B To B. subtilis YqeW gene gene4095 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04096 S100141_04097 S100141_04097 S100141_04097 3821447 3821707 + putative membrane protein YubF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4096 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04097 S100141_04098 S100141_04098 S100141_04098 3821859 3822194 - hypothetical protein gene gene4097 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04098 S100141_04099 S100141_04099 S100141_04099 3822264 3822710 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4098 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04099 S100141_04100 S100141_04100 S100141_04100 3822747 3823214 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4099 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04100 S100141_04101 S100141_04101 S100141_04101 3823528 3823947 - hypothetical protein gene gene4100 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04101 S100141_04102 S100141_04102 S100141_04102 3823944 3824852 - putative transporter YbhF Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene4101 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04102 S100141_04103 S100141_04103 S100141_04103 3824849 3825685 - putative HTH-type transcriptional regulator YbfI DNA-binding%3B Repeat%3B Transcription%3B Transcription regulation%3B Contains 1 HTH araC/xylS-type DNA-binding domain gene gene4102 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04103 S100141_04104 S100141_04104 S100141_04104 3825801 3826214 + hypothetical protein gene gene4103 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04104 S100141_04105 S100141_04105 S100141_04105 3826276 3826743 + hypothetical protein gene gene4104 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04105 S100141_04106 S100141_04106 S100141_04106 3826878 3827495 - hypothetical protein gene gene4105 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04106 S100141_04107 S100141_04107 ybdH ybdH 3827634 3828689 + Glycerol dehydrogenase Glycerol metabolism%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Zinc%3B Catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone (glycerone). Allows microorganisms to utilize glycerol as a source of carbon under anaerobic conditions. Is also able to use various diols as substrates%2C such as propan-1%2C2-diol%2C butan-2%2C3-diol%2C ethan-1%2C2-diol%2C and 3-mercapto-1%2C2- dihydroxypropane%3B Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: bli:BL00169 uncharacterized oxidoreductase%3B Acting on the CH-OH group of donors gene gene4106 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04107 S100141_04108 S100141_04108 S100141_04108 3828862 3830568 + Methyl-accepting chemotaxis protein Cell membrane%3B Chemotaxis%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene4107 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04108 S100141_04109 S100141_04109 S100141_04109 3830594 3831658 + D-xylose-binding periplasmic protein Periplasm%3B Signal%3B Sugar transport%3B Transport%3B Involved in the high-affinity D-xylose membrane transport system. Binds with high affinity to xylose. Belongs to the bacterial solute-binding protein 2 family gene gene4108 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04109 S100141_04110 S100141_04110 ppiC ppiC 3831697 3832464 - Peptidylprolyl isomerase KEGG: gpi:GPICK_07635 peptidyl-prolyl cis-trans isomerase C gene gene4109 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04110 S100141_04111 S100141_04111 S100141_04111 3832619 3833383 - hypothetical protein gene gene4110 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04111 S100141_04112 S100141_04112 S100141_04112 3833708 3834595 + Virginiamycin B lyase Antibiotic resistance%3B Lyase%3B Magnesium%3B Metal-binding%3B Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage%2C generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid%3B Belongs to the Vgb family%3B KEGG: bli:BL01635 virginiamycin B lyase%3B Other carbon-oxygen lyases gene gene4111 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04112 S100141_04113 S100141_04113 S100141_04113 3834632 3835012 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4112 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04113 S100141_04114 S100141_04114 S100141_04114 3835039 3836493 - Leu/Val/Ile amino-acid permease Amino-acid transport%3B Cell membrane%3B Membrane%3B Phosphoprotein%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Permease for leucine%2C valine and isoleucine. Also transports cysteine%2C methionine%2C phenyalanine%2C tyrosine and tryptophan%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2. A. 3. 10) family gene gene4113 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04114 S100141_04115 S100141_04115 S100141_04115 3836493 3837440 - Homocysteine S-methyltransferase Amino-acid biosynthesis%3B Metal-binding%3B Methionine biosynthesis%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Zinc%3B Contains 1 Hcy-binding domain%3B KEGG: bli:BL01781 homocysteine S-methyltransferase gene gene4114 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04115 S100141_04116 S100141_04116 chbG chbG 3837650 3838390 + Chitin disaccharide deacetylase Carbohydrate metabolism%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides%3B Belongs to the YdjC deacetylase family%3B KEGG: dgg:DGI_1411 chitin disaccharide deacetylase gene gene4115 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04116 S100141_04117 S100141_04117 S100141_04117 3838404 3839777 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Kinase%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity). This system may be involved in glucosamine transport%3B Contains 1 PTS EIIA type-1 domain%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bli:BL01637 PTS system%2C N-acetylglucosamine-specific IIB component gene gene4116 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04117 S100141_04118 S100141_04118 S100141_04118 3839866 3840675 + PreQ(1) synthase Activator%3B Coiled coil%3B Cytoplasm%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Global transcriptional regulator that activates transcription of bmr and blt by binding directly to their promoter. Stimulates also the expression of the mta gene itself%2C ydfK and ymfE%3B Contains 1 HTH merR-type DNA-binding domain%3B KEGG: llo:LLO_0515 7-cyano-7-deazaguanine reductase gene gene4117 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04118 S100141_04119 S100141_04119 S100141_04119 3840718 3841440 - UPF0702 transmembrane protein YrbG Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0702 family gene gene4118 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04119 S100141_04120 S100141_04120 S100141_04120 3841428 3842138 - Carbonic anhydrase Lyase%3B Metal-binding%3B Signal%3B Zinc%3B Reversible hydration of carbon dioxide. Essential to photosynthetic carbon dioxide fixation. Belongs to the gamma-class carbonic anhydrase family gene gene4119 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04120 S100141_04121 S100141_04121 S100141_04121 3842662 3843057 - putative membrane protein YjgA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4120 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04121 S100141_04122 S100141_04122 S100141_04122 3843202 3844632 - putative sodium/glutamine symporter GlnT Amino-acid transport%3B Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably functions as a sodium/glutamine symporter for glutamine uptake%3B Belongs to the sodium:alanine (SAF) symporter family gene gene4121 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04122 S100141_04123 S100141_04123 S100141_04123 3844657 3845640 - Glutaminase Hydrolase%3B Belongs to the glutaminase family%3B KEGG: bli:BL01786 glutaminase gene gene4122 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04123 S100141_04124 S100141_04124 ycbA ycbA 3846033 3847358 + Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system GlnK/GlnL that positively regulates the expression of the glsA-glnT operon in response to glutamine. Probably activates GlnL by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bli:BL01640 two-component system%2C sensor histidine kinase YcbA gene gene4123 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04124 S100141_04125 S100141_04125 S100141_04125 3847365 3848300 + Transcriptional regulatory protein GlnL Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system GlnL/GlnK that positively regulates the expression of the glsA-glnT operon in response to glutamine. GlnL binds the promoter region of glsA- glnT in vitro%3B Contains 1 response regulatory domain gene gene4124 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04125 S100141_04126 S100141_04126 S100141_04126 3848343 3848879 - Ribosomal-protein-alanine N-acetyltransferase Acyltransferase%3B Transferase%3B Contains 1 N-acetyltransferase domain%3B KEGG: bli:BL01787 ribosomal-protein-alanine N-acetyltransferase gene gene4125 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04126 S100141_04127 S100141_04127 S100141_04127 3848975 3850774 - Regulatory protein BlaR1 Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B BlaR1 is a potential penicillin-binding protein required for induction of beta-lactamase in Bacillus licheniformis. Belongs to the peptidase M56 family gene gene4126 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04127 S100141_04128 S100141_04128 S100141_04128 3850776 3851162 - Penicillinase repressor Antibiotic resistance%3B Cytoplasm%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcriptional repressor that constitutively blocks expression of beta-lactamase. Regulates genes involved in antibiotic resistance. Binds DNA as a dimer. Belongs to the BlaI transcriptional regulatory family gene gene4127 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04128 S100141_04129 S100141_04129 penP penP 3851585 3852508 + Beta-lactamase Antibiotic resistance%3B Cell membrane%3B Hydrolase%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Belongs to the class-A beta-lactamase family%3B KEGG: bli:BL01642 beta-lactamase class A gene gene4128 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04129 S100141_04130 S100141_04130 S100141_04130 3852853 3854604 + Alkaline phosphatase Hydrolase%3B Signal%3B Stress response%3B Belongs to the PhoD family%3B KEGG: bli:BL01643 alkaline phosphatase D gene gene4129 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04130 S100141_04131 S100141_04131 S100141_04131 3854626 3854838 + Sec-independent protein translocase protein TatAd Cell membrane%3B Cytoplasm%3B Membrane%3B Protein transport%3B Translocation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. Required for PhoD secretion. The cytosolic fraction of TatAd binds the precursor of PhoD%3B Belongs to the TatA/E family gene gene4130 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04131 S100141_04132 S100141_04132 S100141_04132 3854909 3855643 + Sec-independent protein translocase protein TatCd Cell membrane%3B Membrane%3B Protein transport%3B Translocation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Required for PhoD secretion. TatCd promotes membrane localization of TatAd via domain specific interactions. TatCd is required for stabile production of TatAd as well as for its maintenance%3B Belongs to the TatC family gene gene4131 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04132 S100141_04133 S100141_04133 kdgD kdgD 3855839 3856765 + 5-dehydro-4-deoxyglucarate dehydratase Lyase%3B Belongs to the DapA family%3B KEGG: bli:BL01645 5-dehydro-4-deoxyglucarate dehydratase gene gene4132 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04133 S100141_04134 S100141_04134 S100141_04134 3856787 3858253 + Aldehyde dehydrogenase (NAD(+)) NAD%3B Oxidoreductase%3B Oxidizes several aliphatic aldehydes%2C particularly c6- aliphatic aldehyde and hexanal%2C but does not oxidize benzaldehyde. Belongs to the aldehyde dehydrogenase family%3B KEGG: bli:BL01646 aldehyde dehydrogenase (NAD+) gene gene4133 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04134 S100141_04135 S100141_04135 S100141_04135 3858294 3859670 + putative glucarate transporter Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Uptake of D-glucarate. Belongs to the major facilitator superfamily. Phthalate permease family gene gene4134 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04135 S100141_04136 S100141_04136 gudD gudD 3859708 3861075 + Glucarate dehydratase Lyase%3B Magnesium%3B Metal-binding%3B Catalyzes the dehydration of glucarate to 5-keto-4- deoxy-D-glucarate (5-kdGluc)%3B Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily%3B KEGG: bli:BL01649 glucarate dehydratase gene gene4135 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04136 S100141_04137 S100141_04137 S100141_04137 3861170 3861883 + putative HTH-type transcriptional regulator YcbG DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH gntR-type DNA-binding domain gene gene4136 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04137 S100141_04138 S100141_04138 garD garD 3861972 3863498 + Galactarate dehydratase Lyase%3B Catalyzes the dehydration of galactarate to form 5- dehydro-4-deoxy-D-glucarate%3B Belongs to the UxaA family%3B KEGG: bli:BL01651 galactarate dehydratase gene gene4137 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04138 S100141_04139 S100141_04139 S100141_04139 3863661 3864353 + Regulatory protein VirG Activator%3B Crown gall tumor%3B Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Plasmid%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B VirG is required for the positive regulation of at least two vir loci encoded by the Ti plasmid of A. tumefaciens. Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene4138 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04139 S100141_04140 S100141_04140 S100141_04140 3864355 3865290 + Sensor histidine kinase YcbM ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system YcbM/YcbL. Probably activates YcbL by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bcz:BCZK0257 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene4139 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04140 S100141_04141 S100141_04141 S100141_04141 3865385 3866308 + putative ABC transporter ATP-binding protein YcbN ATP-binding%3B Nucleotide-binding%3B Transport%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene4140 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04141 S100141_04142 S100141_04142 S100141_04142 3866323 3867006 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4141 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04142 S100141_04143 S100141_04143 S100141_04143 3867022 3867720 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4142 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04143 S100141_04144 S100141_04144 S100141_04144 3867816 3868895 + uncharacterized protein gene gene4143 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04144 S100141_04145 S100141_04145 S100141_04145 3869053 3870237 + uncharacterized protein gene gene4144 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04145 S100141_04146 S100141_04146 S100141_04146 3870638 3871549 + uncharacterized protein ATP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the aminoglycoside phosphotransferase family gene gene4145 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04146 S100141_04147 S100141_04147 S100141_04147 3871583 3872002 - Organic hydroperoxide resistance transcriptional regulator Cytoplasm%3B DNA-binding%3B Oxidation%3B Repressor%3B Transcription%3B Transcription regulation%3B Organic peroxide sensor. Represses the expression of the peroxide-inducible gene ohrA by cooperative binding to two inverted repeat elements%3B Contains 1 HTH marR-type DNA-binding domain gene gene4146 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04147 S100141_04148 S100141_04148 S100141_04148 3872280 3873791 + Long-chain-fatty-acid--CoA ligase ATP-binding%3B Ligase%3B Nucleotide-binding%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bca:BCE_3436 long-chain acyl-CoA synthetase gene gene4147 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04148 S100141_04149 S100141_04149 S100141_04149 3873920 3875134 + Alpha-1-antitrypsin-like protein CM55-MM Glycoprotein%3B Phosphoprotein%3B Protease inhibitor%3B Pyrrolidone carboxylic acid%3B Secreted%3B Serine protease inhibitor%3B Signal%3B Protease inhibitor%3B Belongs to the serpin family gene gene4148 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04149 S100141_04150 S100141_04150 S100141_04150 3875245 3876072 + hypothetical protein gene gene4149 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04150 S100141_04151 S100141_04151 S100141_04151 3876136 3876963 + hypothetical protein gene gene4150 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04151 S100141_04152 S100141_04152 S100141_04152 3877093 3877845 + HTH-type transcriptional activator mta Activator%3B Coiled coil%3B Cytoplasm%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Global transcriptional regulator that activates transcription of bmr and blt by binding directly to their promoter. Stimulates also the expression of the mta gene itself%2C ydfK and ymfE%3B Contains 1 HTH merR-type DNA-binding domain gene gene4151 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04152 S100141_04153 S100141_04153 S100141_04153 3878058 3878237 + hypothetical protein gene gene4152 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04153 S100141_04154 S100141_04154 S100141_04154 3878254 3878601 + hypothetical protein gene gene4153 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04154 S100141_04155 S100141_04155 S100141_04155 3878594 3879109 + hypothetical protein gene gene4154 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04155 S100141_04156 S100141_04156 S100141_04156 3879526 3879687 + Tryptophan RNA-binding attenuator protein inhibitory protein Cytoplasm%3B Repeat%3B Transcription%3B Transcription regulation. gene gene4155 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04156 S100141_04157 S100141_04157 S100141_04157 3879707 3880651 + putative transporter YcbK Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the EamA transporter family%3B Contains 1 EamA domain gene gene4156 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04157 S100141_04158 S100141_04158 S100141_04158 3880704 3881096 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4157 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04158 S100141_04159 S100141_04159 S100141_04159 3881310 3882377 + uncharacterized protein ATP-binding%3B Nucleotide-binding. gene gene4158 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04159 S100141_04160 S100141_04160 afuC afuC 3882500 3883219 + Fe(3+)-transporting ATPase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3. A. 1. 14. 5) family%3B Contains 1 ABC transporter domain%3B KEGG: pkc:PKB_1433 iron(III) transport system ATP-binding protein gene gene4159 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04160 S100141_04161 S100141_04161 S100141_04161 3883216 3883974 + hypothetical protein gene gene4160 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04161 S100141_04162 S100141_04162 S100141_04162 3883976 3884746 + hypothetical protein gene gene4161 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04162 S100141_04163 S100141_04163 S100141_04163 3884768 3885430 + Transcriptional regulatory protein CpxR like protein Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of a two-component regulatory system%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene4162 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04163 S100141_04164 S100141_04164 S100141_04164 3885421 3886791 + Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system SpaK/SpaR involved in the regulation of the biosynthesis of lantibiotic subtilin. SpaK may function as a membrane-associated protein kinase that phosphorylates SpaR in response to environmental signals. Contains 1 histidine kinase domain%3B KEGG: bmq:BMQ_2600 histidine kinase gene gene4163 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04164 S100141_04165 S100141_04165 S100141_04165 3886864 3887748 - HTH-type transcriptional regulator YtlI Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Positively regulates the expression of ytmI operon in response to the availability of sulfur sources%3B Contains 1 HTH lysR-type DNA-binding domain gene gene4164 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04165 S100141_04166 S100141_04166 S100141_04166 3887858 3888271 + 2-hydroxymuconate tautomerase Isomerase%3B Belongs to the 4-oxalocrotonate tautomerase family%3B KEGG: bte:BTH_II0588 4-oxalocrotonate tautomerase gene gene4165 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04166 S100141_04167 S100141_04167 S100141_04167 3888255 3888995 + 3-oxoacyl-[acyl-carrier-protein] reductase Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B NADP%3B Oxidoreductase%3B Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products%2C the first reductive step in the elongation cycle of fatty acid biosynthesis%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: sfd:USDA257_c20310 3-oxoacyl-(acyl-carrier protein) reductase gene gene4166 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04167 S100141_04168 S100141_04168 S100141_04168 3889083 3891167 + hypothetical protein gene gene4167 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04168 S100141_04169 S100141_04169 S100141_04169 3891178 3892254 - putative lipoprotein YcdA Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal. gene gene4168 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04169 S100141_04170 S100141_04170 S100141_04170 3892870 3894270 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B To E. coli YfcC and H. influenzae HI_0594 gene gene4169 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04170 S100141_04171 S100141_04171 S100141_04171 3894395 3895570 + Peptidase M20 domain-containing protein Polymorphism%3B Belongs to the peptidase M20A family%3B KEGG: tep:TepRe1_0059 amidohydrolase%3B In linear amides gene gene4170 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04171 S100141_04172 S100141_04172 S100141_04172 3895782 3896234 - putative N-acetyltransferase YvbK Acyltransferase%3B Transferase%3B Probable N-acetyltransferase. Contains 1 N-acetyltransferase domain%3B KEGG: vfi:VF_A0653 null%3B Transferring groups other than amino-acyl groups gene gene4171 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04172 S100141_04173 S100141_04173 S100141_04173 3896334 3897833 + Amidase ATP-binding%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)%3B Belongs to the amidase family. GatA subfamily%3B KEGG: blh:BaLi_c03450 amidase gene gene4172 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04173 S100141_04174 S100141_04174 S100141_04174 3897856 3899691 - Oligoendopeptidase F like protein Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Zinc%3B Belongs to the peptidase M3B family%3B KEGG: thl:TEH_06790 oligoendopeptidase F%3B Metalloendopeptidases gene gene4173 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04174 S100141_04175 S100141_04175 S100141_04175 3899804 3900073 - UPF0410 protein YwzA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0410 family gene gene4174 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04175 S100141_04176 S100141_04176 S100141_04176 3900244 3901959 + Serine-type D-Ala-D-Ala carboxypeptidase Antibiotic resistance%3B Cell membrane%3B Cell wall biogenesis/degradation%3B Membrane%3B Signal%3B Affects the methicillin resistance level and autolysis in the presence of Triton X-100 as well as the cell wall structure but its precise function is unknown%3B KEGG: riv:Riv7116_5464 D-alanyl-D-alanine carboxypeptidase gene gene4175 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04176 S100141_04177 S100141_04177 S100141_04177 3902019 3903341 - putative glycolate oxidase iron-sulfur subunit 4Fe-4S%3B Electron transport%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Repeat%3B Transport%3B Contains 2 4Fe-4S ferredoxin-type domains gene gene4176 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04177 S100141_04178 S100141_04178 glcD glcD 3903338 3904750 - (S)-2-hydroxy-acid oxidase FAD%3B Flavoprotein%3B Oxidoreductase%3B Belongs to the FAD-binding oxidoreductase/transferase type 4 family%3B Contains 1 FAD-binding PCMH-type domain%3B KEGG: bli:BL01799 glycolate oxidase gene gene4177 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04178 S100141_04179 S100141_04179 S100141_04179 3904874 3905176 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cytoplasm%3B Kinase%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in cellobiose transport. Contains 1 PTS EIIB type-3 domain%3B KEGG: bli:BL01800 PTS system%2C cellobiose-specific IIB component%3B overlaps another CDS with the same product name gene gene4178 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04179 S100141_04180 S100141_04180 S100141_04180 3905173 3905505 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cytoplasm%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in lichenan transport. Contains 1 PTS EIIA type-3 domain%3B KEGG: bli:BL01801 PTS system%2C cellobiose-specific IIA component%3B overlaps another CDS with the same product name gene gene4179 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04180 S100141_04181 S100141_04181 S100141_04181 3905522 3906808 - Cellobiose permease IIC component Cell membrane%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in cellobiose transport. Contains 1 PTS EIIC type-3 domain gene gene4180 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04181 S100141_04182 S100141_04182 S100141_04182 3906795 3908129 - 6-phospho-beta-glucosidase Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Manganese%3B Metal-binding%3B NAD%3B Hydrolyzes cellobiose 6'-phosphate into glucose 6- phosphate (Glc6P) and glucose. Belongs to the glycosyl hydrolase 4 family%3B KEGG: hav:AT03_20490 6-phospho-beta-glucosidase gene gene4181 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04182 S100141_04183 S100141_04183 S100141_04183 3908291 3909019 + HTH-type transcriptional regulator GmuR Cytoplasm%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcriptional repressor of the gmuBACDREFG operon which is involved in the uptake and degradation of glucomannan%3B Contains 1 HTH gntR-type DNA-binding domain gene gene4182 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04183 S100141_04184 S100141_04184 S100141_04184 3909024 3909758 + Chitin disaccharide deacetylase Carbohydrate metabolism%3B Chitin degradation%3B Cytoplasm%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Polysaccharide degradation%3B Involved in the degradation of chitin. ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer%2C the deacetylated form of chitobiose. Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho- beta-glucosidase ChbF. Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P%2C the inducer of ChbR and the substrate of ChbF%3B Belongs to the YdjC deacetylase family. ChbG subfamily%3B KEGG: blh:BaLi_c03560 chitin disaccharide deacetylase gene gene4183 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04184 S100141_04185 S100141_04185 S100141_04185 3910170 3911957 + Chitinase Carbohydrate metabolism%3B Chitin degradation%3B Glycosidase%3B Hydrolase%3B Polysaccharide degradation%3B Repeat%3B Signal%3B Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily%3B Contains 2 fibronectin type-III domains%3B KEGG: bli:BL01685 chitinase gene gene4184 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04185 S100141_04186 S100141_04186 S100141_04186 3912048 3912530 + Chitinase Carbohydrate metabolism%3B Chitin degradation%3B Glycosidase%3B Hydrolase%3B Periplasm%3B Polysaccharide degradation%3B Signal%3B Hydrolyzes chitin oligosaccharide%3B (GlcNAc)4 to (GlcNAc)2 and (GlcNAc)5%2C6 to (GlcNAc)2 and (GlcNAc)3. Inactive towards chitin%2C glucosamine oligosaccharides%2C glycoproteins and glycopeptides containing (GlcNAc)2. Belongs to the glycosyl hydrolase 18 family%3B KEGG: bli:BL01686 chitinase%3B overlaps another CDS with the same product name gene gene4185 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04186 S100141_04187 S100141_04187 S100141_04187 3912527 3914128 + Chitinase Carbohydrate metabolism%3B Chitin degradation%3B Glycosidase%3B Hydrolase%3B Periplasm%3B Polysaccharide degradation%3B Signal%3B Hydrolyzes chitin oligosaccharide%3B (GlcNAc)4 to (GlcNAc)2 and (GlcNAc)5%2C6 to (GlcNAc)2 and (GlcNAc)3. Inactive towards chitin%2C glucosamine oligosaccharides%2C glycoproteins and glycopeptides containing (GlcNAc)2. Belongs to the glycosyl hydrolase 18 family%3B KEGG: bli:BL01686 chitinase%3B overlaps another CDS with the same product name gene gene4186 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04187 S100141_04188 S100141_04188 sspA sspA 3914187 3915137 - Glutamyl endopeptidase Disulfide bond%3B Hydrolase%3B Protease%3B Secreted%3B Serine protease%3B Signal%3B Specific for hydrolysis of peptide bonds on the carboxyl side of acidic amino acid residues%2C with a strong preference for Glu. Belongs to the peptidase S1B family%3B KEGG: bli:BL01804 glutamyl endopeptidase gene gene4187 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04188 S100141_04189 S100141_04189 S100141_04189 3915309 3916082 + Glucose 1-dehydrogenase (NAD(P)(+)) NADP%3B Oxidoreductase%3B Rhamnose metabolism%3B Involved in the non-phosphorylated metabolic pathway of L-rhamnose catabolism. Catalyzes the oxidation of L-rhamnose to yield L-rhamnono-1%2C4-lactone. It can also oxidize L-lyxose and L- mannose%2C and uses only NADP%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: eta:ETA_30410 glucose 1-dehydrogenase gene gene4188 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04189 S100141_04190 S100141_04190 S100141_04190 3916249 3917067 + hypothetical protein gene gene4189 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04190 S100141_04191 S100141_04191 S100141_04191 3917167 3918564 + uncharacterized protein To B. subtilis YcdC gene gene4190 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04191 S100141_04192 S100141_04192 mpsT mpsT 3918618 3919469 - Thiosulfate sulfurtransferase Repeat%3B Transferase%3B Contains 2 rhodanese domains%3B KEGG: bli:BL01805 thiosulfate/3-mercaptopyruvate sulfurtransferase gene gene4191 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04192 S100141_04193 S100141_04193 S100141_04193 3919627 3920055 + N-acetylmuramoyl-L-alanine amidase Cell wall biogenesis/degradation%3B Germination%3B Hydrolase%3B Secreted%3B Sporulation%3B Probable spore cortex-lytic enzyme involved in the depolymerization of cortex peptidoglycan during germination. Belongs to the CwlJ family%3B KEGG: bli:BL01690 N-acetylmuramoyl-L-alanine amidase gene gene4192 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04193 S100141_04194 S100141_04194 S100141_04194 3920102 3921094 - uncharacterized protein To bacterial alkanal monooxygenase alpha and beta chains%3B KEGG: gfo:GFO_3489 null%3B Oxidoreductases gene gene4193 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04194 S100141_04195 S100141_04195 S100141_04195 3921403 3922761 + Peptidoglycan DL-endopeptidase CwlO Cell wall biogenesis/degradation%3B Hydrolase%3B Secreted%3B Signal%3B Shows a cell wall hydrolytic DL-endopeptidase activity%3B Belongs to the peptidase C40 family gene gene4194 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04195 S100141_04196 S100141_04196 S100141_04196 3922813 3923625 - hypothetical protein gene gene4195 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04196 S100141_04197 S100141_04197 S100141_04197 3923622 3924509 - Arabinose import ATP-binding protein AraG ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Repeat%3B Sugar transport%3B Transport%3B Part of the ABC transporter complex AraFGH involved in arabinose import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Arabinose importer (TC 3. A. 1. 2. 2) family%3B Contains 2 ABC transporter domains%3B KEGG: eco:b1858 zinc transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene4196 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04197 S100141_04198 S100141_04198 S100141_04198 3924659 3925246 + Fatty acid metabolism regulator protein Cytoplasm%3B DNA-binding%3B Fatty acid metabolism%3B Lipid degradation%3B Lipid metabolism%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation%2C including acdA%2C fadA%2C fadB%2C fadE%2C fadF%2C fadG%2C fadH%2C fadM%2C fadN%2C lcfA and lcfB. Binding of FadR to DNA is specifically inhibited by long chain fatty acyl-CoA compounds of 14-20 carbon atoms in length%3B Contains 1 HTH tetR-type DNA-binding domain gene gene4197 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04198 S100141_04199 S100141_04199 S100141_04199 3925349 3927244 + hypothetical protein gene gene4198 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04199 S100141_04200 S100141_04200 S100141_04200 3927276 3927758 - hypothetical protein gene gene4199 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04200 S100141_04201 S100141_04201 S100141_04201 3927751 3928314 - Negative transcription regulator PadR Cytoplasm%3B Repressor%3B Transcription%3B Transcription regulation%3B Negative transcriptional regulator of padC phenolic acid decarboxylase gene gene4200 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04201 S100141_04202 S100141_04202 S100141_04202 3928631 3929233 + General stress protein 16U Stress response%3B Belongs to the CAPAB/TerDEXZ family gene gene4201 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04202 S100141_04203 S100141_04203 S100141_04203 3929262 3929843 + General stress protein 16U Stress response%3B Belongs to the CAPAB/TerDEXZ family gene gene4202 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04203 S100141_04204 S100141_04204 S100141_04204 3929919 3930497 + uncharacterized protein Belongs to the CAPAB/TerDEXZ family gene gene4203 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04204 S100141_04205 S100141_04205 S100141_04205 3930563 3931336 + putative membrane protein YceF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the TerC family gene gene4204 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04205 S100141_04206 S100141_04206 S100141_04206 3931430 3932611 + hypothetical protein gene gene4205 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04206 S100141_04207 S100141_04207 S100141_04207 3932756 3932977 + hypothetical protein gene gene4206 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04207 S100141_04208 S100141_04208 S100141_04208 3932983 3934587 + uncharacterized protein gene gene4207 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04208 S100141_04209 S100141_04209 S100141_04209 3934604 3935698 + uncharacterized protein Belongs to the TelA family gene gene4208 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04209 S100141_04210 S100141_04210 S100141_04210 3935849 3936550 + Cytochrome c-type bioproteinis protein CcdA Cell membrane%3B Cytochrome c-type biogenesis%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane%2C promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat%3B Cytochrome c oxidase activity is partially restored by mutations in bdbC or bdbD that are defective in the synthesis of disulfide bond containing proteins. The same mutations abrogate the need for CcdA in sporulation%3B Belongs to the DsbD family gene gene4209 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04210 S100141_04211 S100141_04211 S100141_04211 3936570 3937256 - hypothetical protein gene gene4210 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04211 S100141_04212 S100141_04212 S100141_04212 3937340 3938080 + HTH-type transcriptional regulator ZntR like protein DNA-binding%3B Transcription%3B Transcription regulation%3B Transcriptional regulator%3B Contains 1 HTH merR-type DNA-binding domain gene gene4211 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04212 S100141_04213 S100141_04213 S100141_04213 3938180 3939385 - Nitrate transporter Cell membrane%3B Membrane%3B Nitrate assimilation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B May function as a nitrate transporter%3B Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2. A. 1. 8) family gene gene4212 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04213 S100141_04214 S100141_04214 S100141_04214 3939835 3940794 + L-lactate dehydrogenase Cytoplasm%3B NAD%3B Oxidoreductase%3B Phosphoprotein%3B Belongs to the LDH/MDH superfamily. LDH family%3B KEGG: bli:BL01703 L-lactate dehydrogenase gene gene4213 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04214 S100141_04215 S100141_04215 S100141_04215 3940844 3942466 + L-lactate permease Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B May play a role in L-lactate transport. Belongs to the lactate permease family gene gene4214 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04215 S100141_04216 S100141_04216 S100141_04216 3942573 3943214 + Putative amino acid efflux protein YcgF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the rht family gene gene4215 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04216 S100141_04217 S100141_04217 S100141_04217 3943215 3944543 - putative transporter YcgH Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene4216 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04217 S100141_04218 S100141_04218 S100141_04218 3944709 3945527 + NAD(+) synthase ATP-binding%3B Ligase%3B NAD%3B Nucleotide-binding%3B Belongs to the NAD synthetase family%3B KEGG: bsu:BSU03130 NAD+ synthase gene gene4217 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04218 S100141_04219 S100141_04219 aroK aroK 3945650 3946183 + Shikimate kinase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B ATP-binding%3B Cytoplasm%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Transferase%3B Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate%3B Belongs to the shikimate kinase family%3B KEGG: rpa:RPA0504 shikimate kinase gene gene4218 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04219 S100141_04220 S100141_04220 S100141_04220 3946475 3947245 + uncharacterized protein Coiled coil. gene gene4219 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04220 S100141_04221 S100141_04221 S100141_04221 3947595 3948512 + Proline dehydrogenase FAD%3B Flavoprotein%3B Oxidoreductase%3B Proline metabolism%3B Catalyzes the oxidation of L-proline to delta-1- pyrroline-5-carboxylate (P5C)%3B Belongs to the proline dehydrogenase family%3B KEGG: bsl:A7A1_1878 proline dehydrogenase%3B Acting on the CH-NH group of donors gene gene4220 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04221 S100141_04222 S100141_04222 S100141_04222 3948536 3950086 + L-glutamate gamma-semialdehyde dehydrogenase NAD%3B Oxidoreductase%3B Belongs to the aldehyde dehydrogenase family. RocA subfamily%3B KEGG: bli:BL01710 1-pyrroline-5-carboxylate dehydrogenase gene gene4221 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04222 S100141_04223 S100141_04223 S100141_04223 3950241 3951665 + Sodium/proline symporter Amino-acid transport%3B Cell inner membrane%3B Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Catalyzes the sodium-dependent uptake of extracellular L-proline. This protein is also capable of using lithium as the transport cation. Also catalyzes the uptake of propionate%3B Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene4222 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04223 S100141_04224 S100141_04224 S100141_04224 3951826 3953070 + Proline-responsive transcriptional activator PutR Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Activates transcription of the putBCP operon. Requires proline as a coactivator%3B Belongs to the CdaR family gene gene4223 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04224 S100141_04225 S100141_04225 S100141_04225 3953108 3953953 - UPF0703 protein YcgQ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0703 family gene gene4224 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04225 S100141_04226 S100141_04226 S100141_04226 3953958 3954845 - UPF0718 protein YcgR Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0718 family gene gene4225 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04226 S100141_04227 S100141_04227 S100141_04227 3955035 3955991 + Cephalosporin-C deacetylase Carbohydrate metabolism%3B Cellulose degradation%3B Cytoplasm%3B Hydrolase%3B Polysaccharide degradation%3B Serine esterase%3B Esterase that removed acetyl groups from a number of O- acetylated small substrates%2C such as acetylated xylose%2C short xylooligosaccharides and cephalosporin C. Has no activity towards polymeric acetylated xylan. Cannot cleave amide linkages%3B Belongs to the carbohydrate esterase 7 family%3B KEGG: bli:BL01713 cephalosporin-C deacetylase gene gene4226 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04227 S100141_04228 S100141_04228 S100141_04228 3956084 3956506 + hypothetical protein gene gene4227 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04228 S100141_04229 S100141_04229 S100141_04229 3956497 3956838 + hypothetical protein gene gene4228 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04229 S100141_04230 S100141_04230 S100141_04230 3956942 3957502 - hypothetical protein gene gene4229 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04230 S100141_04231 S100141_04231 S100141_04231 3957805 3958488 - putative amino-acid ABC transporter permease protein YckA Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene4230 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04231 S100141_04232 S100141_04232 S100141_04232 3958500 3959375 - putative ABC transporter extracellular-binding protein YckB Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B Probably part of a binding-protein-dependent transport system. Belongs to the bacterial solute-binding protein 3 family gene gene4231 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04232 S100141_04233 S100141_04233 S100141_04233 3959559 3960110 + Modulator of drug activity B like protein To E. coli MadB and S. pombe SPAC5H10. 05c gene gene4232 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04233 S100141_04234 S100141_04234 S100141_04234 3960207 3960932 + hypothetical protein gene gene4233 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04234 S100141_04235 S100141_04235 S100141_04235 3961002 3962438 + 6-phospho-beta-glucosidase Disulfide bond%3B Glycoprotein%3B Glycosidase%3B Hydrolase%3B Signal%3B Hydrolyzes p-nitrophenyl beta-D-glucoside%2C p-nitrophenyl beta-D-mannoside%2C p-nitrophenyl beta-D-galactoside%2C p-nitrophenyl beta-D-xyloside%2C p-nitrophenyl beta-D-fucoside%2C p-nitrophenyl beta-L-arabinoside%2C cello-oligosaccharides%2C laminari- oligosaccharides and sophorose%3B Belongs to the glycosyl hydrolase 1 family%3B KEGG: bli:BL01718 6-phospho-beta-glucosidase gene gene4234 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04235 S100141_04236 S100141_04236 S100141_04236 3962477 3962875 - DNA-entry nuclease inhibitor Cell membrane%3B Competence%3B Membrane. gene gene4235 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04236 S100141_04237 S100141_04237 S100141_04237 3962893 3963339 - DNA-entry nuclease Cell membrane%3B Competence%3B Hydrolase%3B Manganese%3B Membrane%3B Nuclease%3B Transmembrane%3B Transmembrane helix%3B By degrading DNA that enters the cell%2C plays a role in the competence of cells to be transformed. Degrades both double- stranded%2C linear and covalently closed circular DNA. To B. subtilis NucB gene gene4236 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04237 S100141_04238 S100141_04238 S100141_04238 3963814 3964617 + Non-specific serine/threonine protein kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Serine/threonine-protein kinase%3B Transferase%3B Belongs to the protein kinase superfamily. Ser/Thr protein kinase family%3B Contains 1 protein kinase domain%3B KEGG: bli:BL01719 serine/threonine protein kinase%2C bacterial gene gene4237 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04238 S100141_04239 S100141_04239 S100141_04239 3964637 3965140 - Transducer protein Car Chemotaxis%3B Cytoplasm%3B Methylation%3B Plasmid%3B Transducer%3B Mediates chemotaxis towards arginine. Probably transduces the signal to the histidine kinase CheA%3B Contains 1 methyl-accepting transducer domain%3B Contains 1 PAS (PER-ARNT-SIM) domain gene gene4238 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04239 S100141_04240 S100141_04240 S100141_04240 3965137 3966315 - Methyl-accepting chemotaxis protein TlpC Cell membrane%3B Chemotaxis%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene4239 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04240 S100141_04241 S100141_04241 S100141_04241 3966437 3967177 - Ribonuclease YobL Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 449-600) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YobK%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene4240 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04241 S100141_04242 S100141_04242 S100141_04242 3967582 3969636 + N-methylhydantoinase (ATP-hydrolyzing) Belongs to the oxoprolinase family%3B KEGG: bli:BL01720 N-methylhydantoinase A gene gene4241 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04242 S100141_04243 S100141_04243 S100141_04243 3969639 3971633 + N-methylhydantoinase (ATP-hydrolyzing) ATP-binding%3B Cytoplasm%3B Hydrolase%3B Nucleotide-binding%3B Catalyzes the cleavage of 5-oxo-L-proline to form L- glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. Acts in the glutathione degradation pathway%3B Belongs to the oxoprolinase family%3B KEGG: bli:BL01721 N-methylhydantoinase B gene gene4242 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04243 S100141_04244 S100141_04244 S100141_04244 3971630 3972718 + hypothetical protein gene gene4243 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04244 S100141_04245 S100141_04245 S100141_04245 3972719 3973846 + Phosphate-transporting ATPase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the ABC transporter superfamily. MsbA family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain%3B KEGG: hde:HDEF_2253 phosphate transport system ATP-binding protein gene gene4244 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04245 S100141_04246 S100141_04246 S100141_04246 3973833 3974699 + Inner membrane ABC transporter permease protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably part of the binding-protein-dependent transport system YdcSTU%3B probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene4245 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04246 S100141_04247 S100141_04247 S100141_04247 3974692 3975504 + Inner membrane ABC transporter permease protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably part of the binding-protein-dependent transport system YdcSTU%3B probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene4246 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04247 S100141_04248 S100141_04248 S100141_04248 3976242 3986990 + Surfactin synthase subunit Antibiotic biosynthesis%3B Ligase%3B Multifunctional enzyme%3B Phosphopantetheine%3B Phosphoprotein%3B Repeat%3B Sporulation%3B This protein is a multifunctional enzyme able to activate and polymerize the amino acids Leu%2C Glu%2C Asp and Val. Activation sites for these AA consist of individual domains. Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 3 acyl carrier domains gene gene4247 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04248 S100141_04249 S100141_04249 S100141_04249 3987010 3997776 + Bacitracin synthase Antibiotic biosynthesis%3B ATP-binding%3B Hydrolase%3B Isomerase%3B Ligase%3B Multifunctional enzyme%3B Nucleotide-binding%3B Phosphopantetheine%3B Phosphoprotein%3B Repeat%3B Induces peptide synthesis%2C activates and incorporates five amino acids%2C forms a thiazoline ring between the first two amino acids and incoporates a D-glutamine in the fourth position. Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 5 acyl carrier domains gene gene4248 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04249 S100141_04250 S100141_04250 S100141_04250 3997834 4001682 + Gramicidin S synthase Antibiotic biosynthesis%3B Hydrolase%3B Ligase%3B Multifunctional enzyme%3B Phosphopantetheine%3B Phosphoprotein%3B Repeat%3B This protein is a multifunctional enzyme%2C able to activate and polymerize the amino acids Pro%2C Val%2C Orn and Leu. Activation sites for these AA consist of individual domains. Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 4 acyl carrier domains gene gene4249 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04250 S100141_04251 S100141_04251 S100141_04251 4001686 4002426 + Surfactin synthase thioesterase subunit Antibiotic biosynthesis%3B Cytoplasm%3B Hydrolase%3B Sporulation%3B Stress response%3B Probable thioesterase involved in the biosynthesis of surfactin. Belongs to the thioesterase family gene gene4250 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04251 S100141_04252 S100141_04252 S100141_04252 4002473 4003384 - putative transporter YcxC Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene4251 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04252 S100141_04253 S100141_04253 S100141_04253 4003520 4004869 + putative HTH-type transcriptional regulator YcxD Aminotransferase%3B DNA-binding%3B Pyridoxal phosphate%3B Transcription%3B Transcription regulation%3B Transferase%3B In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene4252 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04253 S100141_04254 S100141_04254 lys5 lys5 4004881 4005561 - 4'-phosphopantetheinyl transferase Antibiotic biosynthesis%3B Magnesium%3B Metal-binding%3B Transferase%3B May activate the peptidyl carrier protein (PCP) domains of surfactin synthetase SRF1/2/3 and iturin A synthetase%2C by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue. Required for the coproduction of the lipopeptide antibiotics%2C iturin A and surfactin. Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family%3B KEGG: bli:BL01825 4'-phosphopantetheinyl transferase%3B Transferases for other substituted phosphate groups gene gene4253 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04254 S100141_04255 S100141_04255 S100141_04255 4005631 4006446 + uncharacterized protein gene gene4254 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04255 S100141_04256 S100141_04256 S100141_04256 4006692 4007075 + putative HTH-type transcriptional regulator YdeE Cytoplasm%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH araC/xylS-type DNA-binding domain gene gene4255 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04256 S100141_04257 S100141_04257 S100141_04257 4007359 4008021 - putative membrane protein YczE Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4256 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04257 S100141_04258 S100141_04258 S100141_04258 4008277 4008807 + hypothetical protein gene gene4257 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04258 S100141_04259 S100141_04259 S100141_04259 4008834 4009763 + Aliphatic sulfonates import ATP-binding protein SsuB ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3. A. 1. 17. 2) family%3B Contains 1 ABC transporter domain gene gene4258 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04259 S100141_04260 S100141_04260 S100141_04260 4009744 4010643 + hypothetical protein gene gene4259 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04260 S100141_04261 S100141_04261 S100141_04261 4010662 4010835 + hypothetical protein gene gene4260 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04261 S100141_04262 S100141_04262 S100141_04262 4010876 4011115 - hypothetical protein gene gene4261 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04262 S100141_04263 S100141_04263 S100141_04263 4011353 4013014 + Aromatic-L-amino-acid decarboxylase Decarboxylase%3B Lyase%3B Neurotransmitter biosynthesis%3B Phosphoprotein%3B Pyridoxal phosphate%3B Catalyzes the production of GABA%3B Belongs to the group II decarboxylase family%3B KEGG: rxy:Rxyl_1038 aromatic-L-amino-acid decarboxylase gene gene4262 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04263 S100141_04264 S100141_04264 S100141_04264 4013029 4014753 + putative methyl-accepting chemotaxis protein Cell membrane%3B Chemotaxis%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene4263 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04264 S100141_04265 S100141_04265 S100141_04265 4014792 4015535 - Galactose/methyl galactoside import ATP-binding protein MglA ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Repeat%3B Sugar transport%3B Transport%3B Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system (Probable)%3B Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3. A. 1. 2. 3) family%3B Contains 2 ABC transporter domains gene gene4264 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04265 S100141_04266 S100141_04266 S100141_04266 4015551 4016255 - L-cystine transport system permease protein TcyB Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex TcyABC involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable)%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene4265 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04266 S100141_04267 S100141_04267 S100141_04267 4016242 4017048 - L-cystine-binding protein TcyA Amino-acid transport%3B Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B Part of the ABC transporter complex TcyABC involved in L-cystine import%3B Belongs to the bacterial solute-binding protein 3 family gene gene4266 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04267 S100141_04268 S100141_04268 S100141_04268 4017177 4018589 - Arginine utilization regulatory protein RocR Activator%3B Arginine metabolism%3B ATP-binding%3B DNA-binding%3B Nucleotide-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Positive regulator of arginine catabolism. Controls the transcription of the two operons rocABC and rocDEF and probably acts by binding to the corresponding upstream activating sequences%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B Contains 1 sigma-54 factor interaction domain gene gene4267 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04268 S100141_04269 S100141_04269 rocD rocD 4018831 4020033 + Ornithine aminotransferase Amino-acid biosynthesis%3B Aminotransferase%3B Cytoplasm%3B Proline biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Catalyzes the interconversion of ornithine to glutamate semialdehyde%3B Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily%3B KEGG: bli:BL01737 ornithine--oxo-acid transaminase gene gene4268 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04269 S100141_04270 S100141_04270 S100141_04270 4020205 4021650 + putative amino acid permease YvbW Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B May participate in leucine metabolism. May transport leucine or a compound related to leucine metabolism%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene4269 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04270 S100141_04271 S100141_04271 S100141_04271 4021643 4022536 + Arginase Arginine metabolism%3B Hydrolase%3B Manganese%3B Metal-binding%3B Belongs to the arginase family%3B KEGG: aka:TKWG_24915 arginase gene gene4270 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04271 S100141_04272 S100141_04272 S100141_04272 4022605 4023477 - HTH-type transcriptional regulator BsdA Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Could be a positive regulator of bsdBCD expression in response to salicylic acid%3B Contains 1 HTH lysR-type DNA-binding domain gene gene4271 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04272 S100141_04273 S100141_04273 ubiX ubiX 4023600 4024169 + 4-hydroxy-3-polyprenylbenzoate decarboxylase Detoxification%3B Flavoprotein%3B FMN%3B Prenyltransferase%3B Transferase%3B Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for phenolic acid decarboxylase C (By similarity). Involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions (PubMed:18388975)%3B Belongs to the UbiX/PAD1 family. YclB subfamily%3B KEGG: eas:Entas_1524 4-hydroxy-3-polyprenylbenzoate decarboxylase gene gene4272 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04273 S100141_04274 S100141_04274 ubiD ubiD 4024183 4025604 + 4-hydroxy-3-polyprenylbenzoate decarboxylase Aromatic hydrocarbons catabolism%3B Decarboxylase%3B Detoxification%3B Lyase%3B Manganese%3B Metal-binding%3B Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate%2C vanillate and salicylate. Is not active on di- and tri-hydroxybenzoate derivatives%3B Belongs to the UbiD family. YclC subfamily%3B KEGG: sul:SYO3AOP1_0556 4-hydroxy-3-polyprenylbenzoate decarboxylase gene gene4273 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04274 S100141_04275 S100141_04275 S100141_04275 4025624 4025851 + Phenolic acid decarboxylase subunit Aromatic hydrocarbons catabolism%3B Decarboxylase%3B Detoxification%3B Lyase%3B Part of the BsdBCD complex involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate%2C vanillate and salicylate. Is not active on di- and tri-hydroxybenzoate derivatives gene gene4274 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04275 S100141_04276 S100141_04276 S100141_04276 4025867 4026322 + uncharacterized protein gene gene4275 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04276 S100141_04277 S100141_04277 S100141_04277 4026357 4026803 - hypothetical protein gene gene4276 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04277 S100141_04278 S100141_04278 S100141_04278 4026829 4027170 - hypothetical protein gene gene4277 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04278 S100141_04279 S100141_04279 S100141_04279 4027228 4027674 - hypothetical protein gene gene4278 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04279 S100141_04280 S100141_04280 S100141_04280 4027695 4028336 - hypothetical protein gene gene4279 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04280 S100141_04281 S100141_04281 S100141_04281 4028354 4028611 - hypothetical protein gene gene4280 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04281 S100141_04282 S100141_04282 S100141_04282 4028777 4029580 - hypothetical protein gene gene4281 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04282 S100141_04283 S100141_04283 S100141_04283 4029606 4029947 - hypothetical protein gene gene4282 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04283 S100141_04284 S100141_04284 S100141_04284 4029960 4031585 - Ribonuclease YxiD Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene4283 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04284 S100141_04285 S100141_04285 S100141_04285 4031603 4031881 - uncharacterized protein gene gene4284 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04285 S100141_04286 S100141_04286 S100141_04286 4031895 4032278 - uncharacterized protein gene gene4285 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04286 S100141_04287 S100141_04287 S100141_04287 4032780 4033772 + D-allose-binding periplasmic protein Periplasm%3B Signal%3B Sugar transport%3B Transport%3B Part of the binding-protein-dependent transport system AlsBAC for D-allose%3B Belongs to the bacterial solute-binding protein 2 family gene gene4286 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04287 S100141_04288 S100141_04288 S100141_04288 4033759 4035528 + Histidine kinase Cell membrane%3B Chemotaxis%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpB is required for taxis towards asparagine%2C aspartate%2C glutamine%2C and histidine%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain%3B KEGG: bli:BL01744 two-component system%2C sensor histidine kinase YesM gene gene4287 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04288 S100141_04289 S100141_04289 S100141_04289 4035521 4036723 + putative response regulatory protein Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Probable member of the two-component regulatory system SAB0162c/SAB0161c%3B Contains 1 HTH araC/xylS-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene4288 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04289 S100141_04290 S100141_04290 S100141_04290 4036851 4037930 + Multiple sugar-binding periplasmic receptor ChvE Chemotaxis%3B Crown gall tumor%3B Periplasm%3B Signal%3B Required for effective transcriptional induction of the vir genes by monosaccharides in response to plant signals and for normal growth and chemotaxis towards certain sugars. Function as a periplasmic multiple sugar-binding receptor protein. It does not interact with a transport system. Belongs to the bacterial solute-binding protein 2 family gene gene4289 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04290 S100141_04291 S100141_04291 S100141_04291 4037935 4039503 + L-arabinose transport ATP-binding protein AraG ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Repeat%3B Sugar transport%3B Transport%3B Part of the binding-protein-dependent transport system for L-arabinose. Probably responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 2 ABC transporter domains gene gene4290 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04291 S100141_04292 S100141_04292 S100141_04292 4039478 4040689 + Xylose transport system permease protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily gene gene4291 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04292 S100141_04293 S100141_04293 S100141_04293 4040736 4042004 - putative MFS-type transporter YbfB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene4292 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04293 S100141_04294 S100141_04294 yjgM yjgM 4042020 4042937 - Putative HTH-type DNA-binding domain-containing acetyltransferase YbfA Acyltransferase%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Transferase%3B Putative DNA-binding acetyltransferase%3B Contains 1 HTH marR-type DNA-binding domain%3B Contains 1 N-acetyltransferase domain%3B KEGG: bfb:VU15_08170 putative acetyltransferase%3B Transferring groups other than amino-acyl groups gene gene4293 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04294 S100141_04295 S100141_04295 S100141_04295 4043218 4045290 + Beta-galactosidase Glycosidase%3B Hydrolase%3B Metal-binding%3B Zinc%3B Belongs to the glycosyl hydrolase 42 family%3B KEGG: bli:BL01749 beta-galactosidase gene gene4294 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04295 S100141_04296 S100141_04296 S100141_04296 4045525 4046670 - 3-phytase Hydrolase%3B Secreted%3B Signal%3B Catalyzes the hydrolysis of inorganic orthophosphate from phytate. Only phytate%2C ADP%2C and ATP were hydrolyzed (100%2C 75%2C and 50%25 of the relative activity%2C respectively). Contains 1 BPP (beta-propeller phytase) domain%3B KEGG: bli:BL01844 3-phytase gene gene4295 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04296 S100141_04297 S100141_04297 S100141_04297 4046921 4048411 - putative transporter YclF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the PTR2/POT transporter (TC 2. A. 17) family gene gene4296 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04297 S100141_04298 S100141_04298 S100141_04298 4048680 4050437 + uncharacterized protein Repeat%3B Contains 11 PbH1 repeats gene gene4297 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04298 S100141_04299 S100141_04299 S100141_04299 4050461 4050679 - hypothetical protein gene gene4298 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04299 S100141_04300 S100141_04300 S100141_04300 4050774 4052447 + Spore germination protein KA Cell membrane%3B Germination%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Involved in the germination response to the combination of glucose%2C fructose%2C L-asparagine%2C and KCl. Belongs to the GerABKA family gene gene4299 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04300 S100141_04301 S100141_04301 S100141_04301 4052431 4053654 + Spore germination protein KC Cell membrane%3B Germination%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Involved in the germination response to the combination of glucose%2C fructose%2C L-asparagine%2C and KCl. Belongs to the GerABKC lipoprotein family gene gene4300 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04301 S100141_04302 S100141_04302 S100141_04302 4053679 4054785 + Spore germination protein KB Cell membrane%3B Germination%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the germination response to the combination of glucose%2C fructose%2C L-asparagine%2C and KCl. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2. A. 3. 9) family gene gene4301 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04302 S100141_04303 S100141_04303 S100141_04303 4054841 4055569 + HTH-type transcriptional activator TipA Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Transcriptional activator. Is activated when bound to the antibiotic thiostrepton (By similarity)%3B Contains 1 HTH merR-type DNA-binding domain gene gene4302 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04303 S100141_04304 S100141_04304 S100141_04304 4055602 4056285 - Spermidine/putrescine import ATP-binding protein PotA ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3. A. 1. 11. 1) family%3B Contains 1 ABC transporter domain gene gene4303 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04304 S100141_04305 S100141_04305 S100141_04305 4056301 4057740 - putative ABC transporter permease YclI Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the ABC-4 integral membrane protein family gene gene4304 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04305 S100141_04306 S100141_04306 S100141_04306 4057958 4058644 + Cell cycle transcriptional regulator CtrA DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Forms part of a two-component regulatory system CtrA/CckA that controls multiple events in the cell cycle%2C including cell division%2C stalk synthesis and cell cycle-specific transcription. Binds to a group of cell cycle-regulated promoters critical for DNA replication%2C DNA methylation%2C and class II flagellar biogenesis. Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene4305 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04306 S100141_04307 S100141_04307 S100141_04307 4058634 4060061 + Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Could be member of the two-component regulatory system YclK/YclJ. Potentially phosphorylates YclJ%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: gst:HW35_03555 two-component system%2C OmpR family%2C sensor histidine kinase ResE gene gene4306 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04307 S100141_04308 S100141_04308 S100141_04308 4060094 4060885 - Methyl-accepting chemotaxis protein McpB Cell membrane%3B Chemotaxis%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpB is required for taxis towards asparagine%2C aspartate%2C glutamine%2C and histidine%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene4307 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04308 S100141_04309 S100141_04309 S100141_04309 4060900 4061799 - Methyl-accepting chemotaxis protein McpA Cell membrane%3B Chemotaxis%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpA is required for taxis towards glucose and alpha-methylglucoside%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene4308 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04309 S100141_04310 S100141_04310 S100141_04310 4061935 4063296 - Aspartate kinase Amino-acid biosynthesis%3B ATP-binding%3B Diaminopimelate biosynthesis%3B Kinase%3B Lysine biosynthesis%3B Nucleotide-binding%3B Repeat%3B Transferase%3B Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate%2C which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine%2C isoleucine and methionine%3B Belongs to the aspartokinase family%3B Contains 2 ACT domains%3B KEGG: bsu:BSU03790 aspartate kinase gene gene4309 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04310 S100141_04311 S100141_04311 S100141_04311 4063573 4064526 + putative ABC transporter permease protein YclN Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably part of an ABC transporter complex. Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene4310 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04311 S100141_04312 S100141_04312 S100141_04312 4064516 4065460 + putative ABC transporter permease protein YclO Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably part of an ABC transporter complex. Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene4311 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04312 S100141_04313 S100141_04313 S100141_04313 4065460 4066218 + Polar-amino-acid-transporting ATPase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Phosphonate transport%3B Transport%3B Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3. A. 1. 9. 1) family%3B Contains 1 ABC transporter domain%3B KEGG: msu:MS1685 polar amino acid transport system ATP-binding protein gene gene4312 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04313 S100141_04314 S100141_04314 S100141_04314 4066233 4067180 + Putative ABC transporter substrate-binding lipoprotein YhfQ Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene4313 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04314 S100141_04315 S100141_04315 S100141_04315 4067349 4068770 - MFS antiporter QDR2 Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Virulence%3B MFS antiporter that does not display functional linkage as drug transporter and performs functions that significantly affect biofilm development and virulence. No substrate for transport has been identified yet%2C but plays an important role in the growth in the host%3B Belongs to the major facilitator superfamily. CAR1 family gene gene4314 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04315 S100141_04316 S100141_04316 S100141_04316 4068782 4069669 - putative HTH-type transcriptional regulator YcnC DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH tetR-type DNA-binding domain gene gene4315 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04316 S100141_04317 S100141_04317 S100141_04317 4069764 4070606 - Carboxyvinyl-carboxyphosphonate phosphorylmutase KEGG: sen:SACE_4109 carboxyvinyl-carboxyphosphonate phosphorylmutase gene gene4316 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04317 S100141_04318 S100141_04318 S100141_04318 4070717 4071454 - FMN reductase (NAD(P)H) Aromatic hydrocarbons catabolism%3B Detoxification%3B Flavoprotein%3B FMN%3B NAD%3B Oxidoreductase%3B Reduces FMNH(2) to FMN%2C with NADH or NADPH as reductant. It also reduces nitroaromatic compounds%2C quinones%2C chromates and azo dyes. It could supply the reduced form of FMN to luciferase- like protein and contribute to the degradation of aromatic compounds%3B Belongs to the flavin oxidoreductase frp family%3B KEGG: bsu:BSU03860 FMN reductase (NAD(P)H) gene gene4317 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04318 S100141_04319 S100141_04319 S100141_04319 4071473 4071760 - Putative monooxygenase YcnE Aromatic hydrocarbons catabolism%3B Detoxification%3B Monooxygenase%3B Oxidoreductase%3B Phosphoprotein%3B Putative monooxygenase that may contribute to the degradation of aromatic compounds%3B Belongs to the LsrG family%3B Contains 1 ABM domain gene gene4318 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04319 S100141_04320 S100141_04320 S100141_04320 4071938 4072234 + putative HTH-type transcriptional regulator YczG DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH arsR-type DNA-binding domain gene gene4319 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04320 S100141_04321 S100141_04321 S100141_04321 4072299 4073729 - HTH-type transcriptional regulatory protein GabR Activator%3B Aminotransferase%3B DNA-binding%3B Pyridoxal phosphate%3B Repressor%3B Transcription%3B Transcription regulation%3B Transferase%3B Activates the transcription of the gabTD operon. Is also a repressor of its own expression%2C both in the presence and absence of GABA. Binds specifically to the DNA region overlapping the -35 region of the gabT promoter and the -10 and +1 regions of the gabR promoter. Principally regulates the utilization of gamma- aminobutyrate%3B In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene4320 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04321 S100141_04322 S100141_04322 gabT gabT 4073832 4075145 + 4-aminobutyrate--2-oxoglutarate transaminase Aminotransferase%3B Pyridoxal phosphate%3B Transferase%3B Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bli:BL01762 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase gene gene4321 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04322 S100141_04323 S100141_04323 S100141_04323 4075179 4076570 + Amino-acid permease RocE Amino-acid transport%3B Arginine metabolism%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Putative transport protein involved in arginine degradative pathway. Probably transports arginine or ornithine. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2. A. 3. 1) family gene gene4322 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04323 S100141_04324 S100141_04324 gabD gabD 4076545 4077939 + Succinate-semialdehyde dehydrogenase (NAD(P)(+)) Cytoplasm%3B NAD%3B Oxidoreductase%3B Converts 9-cis-retinal to 9-cis-retinoic acid. Has lower activity towards 13-cis-retinal. Has much lower activity towards all-trans-retinal. Has highest activity with benzaldehyde and decanal (in vitro). Has a preference for NAD%2C but shows considerable activity with NADP (in vitro) (By similarity)%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: bli:BL01765 succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase gene gene4323 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04324 S100141_04325 S100141_04325 S100141_04325 4077986 4078870 - putative transporter YwfM Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene4324 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04325 S100141_04326 S100141_04326 S100141_04326 4079035 4079526 + hypothetical protein gene gene4325 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04326 S100141_04327 S100141_04327 S100141_04327 4079574 4080218 - uncharacterized protein Cell membrane%3B Membrane%3B Signal%3B Transmembrane%3B Transmembrane helix. gene gene4326 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04327 S100141_04328 S100141_04328 S100141_04328 4080221 4081858 - Copper transport protein YcnJ Cell membrane%3B Copper%3B Copper transport%3B Ion transport%3B Membrane%3B Metal-binding%3B Signal%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in uptake of extracellular oxidized copper under copper-limiting conditions%3B In the N-terminal sectio%3B belongs to the CopC family%3B In the C-terminal sectio%3B belongs to the CopD family gene gene4327 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04328 S100141_04329 S100141_04329 S100141_04329 4081887 4082459 - putative HTH-type transcriptional regulator YgbI DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH deoR-type DNA-binding domain gene gene4328 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04329 S100141_04330 S100141_04330 nirB nirB 4082720 4085014 + Nitrite reductase (NADH) Electron transport%3B FAD%3B Flavoprotein%3B NADP%3B Nitrate assimilation%3B Transport%3B Required for nitrate assimilation%3B KEGG: mmt:Metme_3418 nitrite reductase (NADH) large subunit gene gene4329 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04330 S100141_04331 S100141_04331 nasA nasA 4085016 4087175 + Nitrate reductase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Molybdenum%3B Nitrate assimilation%3B Oxidoreductase%3B Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants%2C fungi and bacteria. Belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: bsu:BSU03310 assimilatory nitrate reductase catalytic subunit gene gene4330 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04331 S100141_04332 S100141_04332 S100141_04332 4087289 4089709 + Nitrite reductase (NADH) 4Fe-4S%3B FAD%3B Flavoprotein%3B Heme%3B Iron%3B Iron-sulfur%3B Metal-binding%3B NADP%3B Nitrate assimilation%3B Oxidoreductase%3B Required for nitrite assimilation%3B Belongs to the nitrite and sulfite reductase 4Fe-4S domain family%3B KEGG: bsu:BSU03300 nitrite reductase (NADH) large subunit gene gene4331 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04332 S100141_04333 S100141_04333 nirD nirD 4089740 4090060 + Nitrite reductase (NADH) 2Fe-2S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B NAD%3B Nitrate assimilation%3B Oxidoreductase%3B Required for nitrite assimilation. Required for activity of the reductase (By similarity)%3B Contains 1 Rieske domain%3B KEGG: bsu:BSU03290 nitrite reductase (NADH) small subunit gene gene4332 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04333 S100141_04334 S100141_04334 S100141_04334 4090178 4091638 + Uroporphyrinogen-III C-methyltransferase Methyltransferase%3B Porphyrin biosynthesis%3B S-adenosyl-L-methionine%3B Transferase%3B Belongs to the precorrin methyltransferase family%3B KEGG: bli:BL01771 uroporphyrinogen III methyltransferase / synthase gene gene4333 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04334 S100141_04335 S100141_04335 S100141_04335 4091664 4092344 - HTH-type transcriptional repressor CsiR Cytoplasm%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Modulates expression of csiD and lhgO in a temporal manner during entry into stationary phase or during the first few hours of carbon starvation%3B Contains 1 HTH gntR-type DNA-binding domain gene gene4334 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04335 S100141_04336 S100141_04336 S100141_04336 4092573 4094213 + Sodium-dependent dicarboxylate transporter SdcS Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mediates the transport of the dicarboxylates fumarate%2C malate%2C and succinate across the cytoplasmic membrane via a Na(+)- electrochemical gradient%3B Belongs to the SLC13A/DASS transporter (TC 2. A. 47) family. NADC subfamily gene gene4335 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04336 S100141_04337 S100141_04337 S100141_04337 4094302 4094487 + 3-hydroxyacyl-[acyl-carrier-protein] dehydratase Belongs to the thioester dehydratase family. FabZ subfamily%3B KEGG: bamt:AJ82_02350 3-hydroxyacyl-(acyl-carrier-protein) dehydratase gene gene4336 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04337 S100141_04338 S100141_04338 fwdE fwdE 4094741 4095208 + Formylmethanofuran dehydrogenase Alternative splicing%3B Hydrolase%3B Hydrolyzes acyl-CoA thioesters (in vitro). Has a preference for substrates with medium chain length (C10-C14). Inactive towards substrates with C18 or C20 aliphatic chains. Its physiological substrate is not known (By similarity)%3B Contains 1 TsaA-like domain%3B KEGG: aar:Acear_0784 formylmethanofuran dehydrogenase subunit E gene gene4337 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04338 S100141_04339 S100141_04339 ulaC ulaC 4095374 4097425 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cytoplasm%3B Kinase%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in mannitol transport (By similarity)%3B Contains 1 PTS EIIA type-2 domain%3B KEGG: bcl:ABC0945 PTS system%2C ascorbate-specific IIA component gene gene4338 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04339 S100141_04340 S100141_04340 ulaB ulaB 4097442 4097723 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase KEGG: efe:EFER_0867 PTS system%2C ascorbate-specific IIB component gene gene4339 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04340 S100141_04341 S100141_04341 S100141_04341 4097747 4099120 + Ascorbate-specific permease IIC component UlaA Cell inner membrane%3B Cell membrane%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active- transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in ascorbate transport (By similarity)%3B Belongs to the UlaA family gene gene4340 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04341 S100141_04342 S100141_04342 S100141_04342 4099135 4099977 + Transketolase Calcium%3B Magnesium%3B Metal-binding%3B Thiamine pyrophosphate%3B Transferase%3B Plays an essential role in total transketolase activity and cell proliferation in cancer cell%3B after transfection with anti-TKTL1 siRNA%2C total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells. Plays a pivotal role in carcinogenesis (By similarity)%3B Belongs to the transketolase family%3B KEGG: bli:BL01777 transketolase%3B overlaps another CDS with the same product name gene gene4341 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04342 S100141_04343 S100141_04343 S100141_04343 4099974 4100924 + Transketolase Isoprene biosynthesis%3B Magnesium%3B Metal-binding%3B Thiamine biosynthesis%3B Thiamine pyrophosphate%3B Transferase%3B Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)%3B Belongs to the transketolase family. DXPS subfamily%3B KEGG: bli:BL05028 transketolase%3B overlaps another CDS with the same product name gene gene4342 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04343 S100141_04344 S100141_04344 S100141_04344 4100999 4101754 + Putative phosphatase YcsE Hydrolase%3B Magnesium%3B Metal-binding%3B Belongs to the HAD-like hydrolase superfamily. Cof family gene gene4343 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04344 S100141_04345 S100141_04345 S100141_04345 4102041 4102802 + UPF0271 protein Belongs to the UPF0271 (lamB) family gene gene4344 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04345 S100141_04346 S100141_04346 S100141_04346 4102827 4104038 + putative membrane protein YcsG Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the NRAMP family gene gene4345 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04346 S100141_04347 S100141_04347 S100141_04347 4104035 4104832 + UPF0317 protein Belongs to the UPF0317 family gene gene4346 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04347 S100141_04348 S100141_04348 S100141_04348 4104910 4105644 + Kinase A inhibitor ATP-binding%3B Nucleotide-binding%3B Protein kinase inhibitor%3B Sporulation%3B Is a potent inhibitor of the autophosphorylation reaction of kinase A and its reverse reaction%2C but does not inhibit phosphate transfer to the Spo0F response regulator once kinase A is phosphorylated. KipI is an inhibitor of the catalytic domain of kinase A affecting the ATP/ADP reactions and not the phosphotransferase functions of this domain. The inhibition is noncompetitive with respect to ATP gene gene4347 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04348 S100141_04349 S100141_04349 S100141_04349 4105641 4106654 + KipI antagonist Sporulation%3B Counteracts the inhibitory action of KipI on sporulation. May bind to KipI%2C preventing its function as an inhibitor of kinase A gene gene4348 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04349 S100141_04350 S100141_04350 S100141_04350 4106686 4107435 + HTH-type transcriptional regulator KipR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcriptional repressor of the kip gene-containing operon%3B Contains 1 HTH iclR-type DNA-binding domain%3B Contains 1 iclR-ED (iclR effector binding) domain gene gene4349 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04350 S100141_04351 S100141_04351 S100141_04351 4107524 4108162 + Spore germination lipase LipC Hydrolase%3B Sporulation%3B Lipase involved in spore germination%3B Belongs to the 'GDSL' lipolytic enzyme family gene gene4350 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04351 S100141_04352 S100141_04352 mtlA mtlA 4108407 4109831 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Kinase%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in mannitol transport (By similarity)%3B Contains 1 PTS EIIB type-2 domain%3B Contains 1 PTS EIIC type-2 domain%3B KEGG: bld:BLi00505 PTS system%2C mannitol-specific IIB component gene gene4351 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04352 S100141_04353 S100141_04353 S100141_04353 4109898 4110338 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Kinase%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in mannitol transport (By similarity)%3B Contains 1 PTS EIIA type-2 domain%3B Contains 1 PTS EIIB type-2 domain%3B Contains 1 PTS EIIC type-2 domain%3B KEGG: bld:BLi00506 PTS system%2C mannitol-specific IIA component gene gene4352 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04353 S100141_04354 S100141_04354 mtlD mtlD 4110335 4111474 + Mannitol-1-phosphate 5-dehydrogenase NAD%3B Oxidoreductase%3B Belongs to the mannitol dehydrogenase family%3B KEGG: eco:b3600 mannitol-1-phosphate 5-dehydrogenase gene gene4353 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04354 S100141_04355 S100141_04355 S100141_04355 4111754 4113832 + Transcriptional regulator MtlR Activator%3B DNA-binding%3B Kinase%3B Phosphoprotein%3B Repeat%3B Transcription%3B Transcription regulation%3B Transferase%3B Positively regulates the expression of the mtlAFD operon involved in the uptake and catabolism of mannitol%3B Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains%3B Contains 1 PTS EIIA type-2 domain%3B Contains 1 PTS EIIB type-2 domain gene gene4354 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04355 S100141_04356 S100141_04356 S100141_04356 4113945 4114814 + General stress protein 39 Oxidoreductase%3B Stress response%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bli:BL02817 null%3B Oxidoreductases gene gene4355 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04356 S100141_04357 S100141_04357 S100141_04357 4114830 4115333 + putative D-lyxose ketol-isomerase Carbohydrate metabolism%3B Isomerase%3B Manganese%3B Metal-binding%3B Belongs to the D-lyxose ketol-isomerase family gene gene4356 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04357 S100141_04358 S100141_04358 S100141_04358 4115350 4115733 - hypothetical protein gene gene4357 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04358 S100141_04359 S100141_04359 S100141_04359 4115819 4116241 + General stress protein Stress response. gene gene4358 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04359 S100141_04360 S100141_04360 S100141_04360 4116694 4117503 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4359 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04360 S100141_04361 S100141_04361 S100141_04361 4117668 4118609 + Regulatory protein MsrR Cell membrane%3B Membrane%3B Signal-anchor%3B Transcription%3B Transcription regulation%3B Transmembrane%3B Transmembrane helix%3B Involved in SarA attenuation. Affects resistance to oxacillin and teicoplanin%2C as well as the synthesis of virulence factors%3B Belongs to the LytR/CpsA/Psr regulatory protein family gene gene4360 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04361 S100141_04362 S100141_04362 S100141_04362 4118641 4118934 - putative membrane protein YdzA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4361 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04362 S100141_04363 S100141_04363 S100141_04363 4119018 4119428 - hypothetical protein gene gene4362 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04363 S100141_04364 S100141_04364 S100141_04364 4119546 4119974 + HTH-type transcriptional regulator LrpA DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Negative regulation of glyA transcription and kinB- dependent sporulation%3B Contains 1 HTH asnC-type DNA-binding domain gene gene4363 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04364 S100141_04365 S100141_04365 topB topB 4120015 4122231 + DNA topoisomerase DNA-binding%3B Isomerase%3B Magnesium%3B Metal-binding%3B Topoisomerase%3B Releases the supercoiling and torsional tension of DNA%2C which is introduced during the DNA replication and transcription%2C by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme%2C resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand%2C thus removing DNA supercoils. Finally%2C in the religation step%2C the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone%3B Belongs to the type IA topoisomerase family%3B Contains 1 Toprim domain%3B KEGG: bld:BLi00518 DNA topoisomerase III gene gene4364 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04365 S100141_04366 S100141_04366 S100141_04366 4122919 4124391 + putative amino acid permease YdaO Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene4365 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04366 S100141_04367 S100141_04367 S100141_04367 4124416 4124739 + putative amino acid permease YdaO Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene4366 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04367 S100141_04368 S100141_04368 poxL poxL 4124847 4126568 + Pyruvate oxidase FAD%3B Flavoprotein%3B Magnesium%3B Metal-binding%3B Oxidoreductase%3B Thiamine pyrophosphate%3B Important for the aerobic growth. Decarboxylates pyruvate in four steps. The energy released is partially stored in acetyl phosphate. Belongs to the TPP enzyme family%3B KEGG: bli:BL00146 pyruvate oxidase gene gene4367 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04368 S100141_04369 S100141_04369 S100141_04369 4126709 4127320 + GlcNAc-binding protein Chitin-binding%3B Secreted%3B Signal%3B Probably interacts with GlcNAc residues. May promote attachment to both epithelial cell surfaces and chitin%3B Belongs to the GbpA family%3B Contains 1 chitin-binding type-3 domain%3B Contains 1 chitin-binding type-4 domain gene gene4368 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04369 S100141_04370 S100141_04370 S100141_04370 4127508 4127723 + hypothetical protein gene gene4369 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04370 S100141_04371 S100141_04371 S100141_04371 4127720 4127839 + hypothetical protein gene gene4370 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04371 S100141_04372 S100141_04372 S100141_04372 4127809 4128669 + putative transposase-like protein DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene4371 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04372 S100141_04373 S100141_04373 S100141_04373 4128734 4128985 - putative membrane protein YdzK Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4372 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04373 S100141_04374 S100141_04374 rimL rimL 4129057 4129608 - Putative ribosomal N-acetyltransferase YdaF Acyltransferase%3B Transferase%3B Putative N-acetyltransferase. May act on ribosomal proteins (Potential)%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bli:BL00141 ribosomal-protein-serine acetyltransferase%3B Transferring groups other than amino-acyl groups gene gene4373 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04374 S100141_04375 S100141_04375 S100141_04375 4129663 4130943 - Divalent metal cation transporter MntH Cell membrane%3B Ion transport%3B Manganese%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B H(+)-stimulated%2C divalent metal cation uptake system. Involved in manganese uptake. Can probably also transport cadmium%2C cobalt%2C copper and zinc%2C but not iron. May be the predominant transporter of manganese during logarithmic phase growth%3B Belongs to the NRAMP family gene gene4374 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04375 S100141_04376 S100141_04376 S100141_04376 4131126 4131374 - UPF0410 protein YdaS Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0410 family gene gene4375 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04376 S100141_04377 S100141_04377 S100141_04377 4131470 4132891 - Aspartate ammonia-lyase Lyase%3B Belongs to the class-II fumarase/aspartase family. Aspartase subfamily%3B KEGG: bli:BL02922 aspartate ammonia-lyase gene gene4376 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04377 S100141_04378 S100141_04378 S100141_04378 4133200 4134384 + putative UDP-glucosyltransferase YdhE Glycosyltransferase%3B Transferase%3B Belongs to the UDP-glycosyltransferase family%3B KEGG: sma:SAV_945 dTDP-L-oleandrosyltransferase%3B Hexosyltransferases gene gene4377 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04378 S100141_04379 S100141_04379 S100141_04379 4134410 4134856 - uncharacterized protein gene gene4378 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04379 S100141_04380 S100141_04380 S100141_04380 4134975 4135799 + uncharacterized protein gene gene4379 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04380 S100141_04381 S100141_04381 S100141_04381 4135839 4137128 - Malate-2H(+)/Na(+)-lactate antiporter Antiport%3B Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Couples proton uptake and Na(+) efflux to the substrate- product malate/lactate antiport%2C in an electroneutral malate- 2H(+)/Na(+)-lactate exchange. Plays a role in supporting growth to high density on malate at reduced protonmotive force. Belongs to the NhaC Na(+)/H(+) (TC 2. A. 35) antiporter family gene gene4380 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04381 S100141_04382 S100141_04382 S100141_04382 4137257 4137973 + uncharacterized protein Belongs to the SchB/CurC family gene gene4381 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04382 S100141_04383 S100141_04383 S100141_04383 4138048 4138488 + Glucose starvation-inducible protein Repeat%3B Stress response. gene gene4382 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04383 S100141_04384 S100141_04384 S100141_04384 4138710 4139750 + UPF0118 membrane protein YdbI Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0118 (PerM) family gene gene4383 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04384 S100141_04385 S100141_04385 S100141_04385 4140038 4141282 + C4-dicarboxylate transport protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Plasmid%3B Sugar transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Responsible for the transport of dicarboxylates such as succinate%2C fumarate%2C and malate from the periplasm across the membrane%3B Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family gene gene4384 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04385 S100141_04386 S100141_04386 S100141_04386 4141352 4142278 + Zinc import ATP-binding protein ZnuC ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Ion transport%3B Membrane%3B Nucleotide-binding%3B Transport%3B Zinc%3B Zinc transport%3B Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Zinc importer (TC 3. A. 1. 15. 5) family%3B Contains 1 ABC transporter domain gene gene4385 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04386 S100141_04387 S100141_04387 S100141_04387 4142271 4143038 + putative membrane protein YdbK Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4386 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04387 S100141_04388 S100141_04388 S100141_04388 4143138 4143494 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4387 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04388 S100141_04389 S100141_04389 S100141_04389 4143619 4144767 + Medium-chain acyl-CoA dehydrogenase FAD%3B Flavoprotein%3B Oxidoreductase%3B Belongs to the acyl-CoA dehydrogenase family%3B KEGG: bcz:BCZK2818 acyl-CoA dehydrogenase gene gene4388 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04389 S100141_04390 S100141_04390 S100141_04390 4144841 4144996 - uncharacterized protein gene gene4389 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04390 S100141_04391 S100141_04391 S100141_04391 4144999 4145157 - hypothetical protein gene gene4390 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04391 S100141_04392 S100141_04392 S100141_04392 4145573 4145893 - Thioredoxin Disulfide bond%3B Electron transport%3B Redox-active center%3B Transport%3B Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions%3B Belongs to the thioredoxin family%3B Contains 1 thioredoxin domain gene gene4391 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04392 S100141_04393 S100141_04393 S100141_04393 4146054 4147139 + D-alanine--D-alanine ligase ATP-binding%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Ligase%3B Magnesium%3B Manganese%3B Metal-binding%3B Nucleotide-binding%3B Peptidoglycan synthesis%3B Cell wall formation%3B Belongs to the D-alanine--D-alanine ligase family%3B Contains 1 ATP-grasp domain%3B KEGG: bli:BL02193 D-alanine-D-alanine ligase gene gene4392 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04393 S100141_04394 S100141_04394 murF murF 4147172 4148647 + UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase ATP-binding%3B Cell cycle%3B Cell division%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Peptidoglycan synthesis%3B Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide%2C the precursor of murein%3B Belongs to the MurCDEF family. MurF subfamily%3B KEGG: bld:BLi00544 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase gene gene4393 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04394 S100141_04395 S100141_04395 S100141_04395 4148707 4149423 + Carboxylesterase KEGG: paa:Paes_2227 carboxylesterase gene gene4394 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04395 S100141_04396 S100141_04396 deaD deaD 4149774 4151237 + RNA helicase ATP-binding%3B Cytoplasm%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B RNA-binding%3B Stress response%3B DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions%2C has RNA- dependent ATPase activity%3B Belongs to the DEAD box helicase family. CshA subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bsu:BSU04580 ATP-dependent RNA helicase DeaD gene gene4395 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04396 S100141_04397 S100141_04397 S100141_04397 4151351 4151830 + UPF0699 transmembrane protein YdbS Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0699 family gene gene4396 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04397 S100141_04398 S100141_04398 S100141_04398 4151820 4153301 + UPF0699 transmembrane protein YdbT Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0699 family gene gene4397 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04398 S100141_04399 S100141_04399 S100141_04399 4153298 4153897 - Putative rhomboid protease YdcA Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Belongs to the peptidase S54 family gene gene4398 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04399 S100141_04400 S100141_04400 S100141_04400 4154192 4155199 + Sporulation protein YdcC Cell membrane%3B Membrane%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B required for efficient sporulation gene gene4399 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04400 S100141_04401 S100141_04401 S100141_04401 4155421 4156593 + Alanine racemase Isomerase%3B Pyridoxal phosphate%3B Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids%3B Belongs to the alanine racemase family%3B KEGG: bld:BLi00551 alanine racemase gene gene4400 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04401 S100141_04402 S100141_04402 S100141_04402 4156705 4156986 + Antitoxin EndoAI Antitoxin component of a type II toxin-antitoxin (TA) module. Antitoxin that directly inhibits activity of EndoA in vitro. Upon expression in E. coli counteracts inhibitory effect of endoribonuclease EndoA. The EndoA-EndoAI complex does not seem to bind its own promoter (PubMed:24120662)%3B Belongs to the MazE/EndoAI family gene gene4401 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04402 S100141_04403 S100141_04403 mazF mazF 4156991 4157341 + Endoribonuclease EndoA Endonuclease%3B Hydrolase%3B Nuclease%3B RNA-binding%3B Toxin%3B Toxic component of a type II toxin-antitoxin (TA) module. Specific for 5'-UACAU-3' sequences%2C cleaving after the first U (PubMed:21763692). Yields cleavage products with 3' phosphate and 5' hydroxyl groups (PubMed:15882409). Cannot digest substrate with a UUdUACAUAA cleavage site (PubMed:24120662). Overexpression is toxic for cell growth (shown in E. coli)%2C probably by inhibiting protein synthesis through the cleavage of single-stranded RNA. The toxicity is reversed by the antitoxin EndoAI. Toxin activity cannot be inhibited by MazE from E. coli. The EndoA-EndoAI complex does not seem to bind its own promoter (PubMed:24120662)%3B Belongs to the PemK/MazF family%3B KEGG: bsu:BSU04660 mRNA interferase MazF%3B Acting on ester bonds gene gene4402 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04403 S100141_04404 S100141_04404 S100141_04404 4157459 4158286 + RsbT co-antagonist protein RsbRA Phosphoprotein%3B Acts as a positive regulator of sigma-B activity in response to salt and heat stress by stimulating the activity of the RsbT kinase toward RsbS in vitro. One of 4 functionally non-identical RsbR paralogs%2C it functions in the environmental signaling branch of the general stress response. Negative regulator of sigma-B activity. Non- phosphorylated RsbS binds to RsbT%2C preventing its association with RsbU. Requires any one of RsbRA%2C RsbRB%2C RsbRC or RsbRD to sequester RsbT. When RsbS and the RsbR paralog(s) are phosphorylated%2C they release RsbT%2C which can then bind and activate RsbU. Contains 1 STAS domain gene gene4403 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04404 S100141_04405 S100141_04405 S100141_04405 4158290 4158655 + RsbT antagonist protein RsbS Phosphoprotein%3B Negative regulator of sigma-B activity. Non- phosphorylated RsbS binds to RsbT%2C preventing its association with RsbU. Requires any one of RsbRA%2C RsbRB%2C RsbRC or RsbRD to sequester RsbT. When RsbS and the RsbR paralog(s) are phosphorylated%2C they release RsbT%2C which can then bind and activate RsbU%3B Contains 1 STAS domain gene gene4404 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04405 S100141_04406 S100141_04406 rsbT rsbT 4158658 4159059 + Non-specific serine/threonine protein kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Serine/threonine-protein kinase%3B Transferase%3B Provides the crucial link between the upstream module (communication of environmental stress) and the downstream module (integration of the environmental signals with signals of energy stress) that compose the signal transduction pathway controlling the sigma-B factor. Phosphorylates and inactivates its specific antagonist protein RsbS thanks to its serine kinase activity. Upon phosphorylation of RsbS%2C RsbT is released to stimulate RsbU%2C a PP2C phosphatase%2C thereby initiating the signaling cascade that ultimately activates sigma-B. The activity of the RsbU phosphatase may be stimulated by a long-lived interaction with RsbT and the serine kinase function of RsbT is not required to directly modify RsbU. Also phosphorylates RsbR thanks to its threonine kinase activity%2C preventing it to phosphorylate RsbT%3B KEGG: bsu:BSU04690 serine/threonine-protein kinase RsbT gene gene4405 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04406 S100141_04407 S100141_04407 S100141_04407 4159070 4160077 + Phosphoserine phosphatase RsbU Hydrolase%3B Protein phosphatase%3B Positive regulator of sigma-B activity. Dephosphorylates RsbV in response to environmental stress conveyed from the RsbXST module%3B Contains 1 PPM-type phosphatase domain gene gene4406 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04407 S100141_04408 S100141_04408 S100141_04408 4160136 4160462 + Anti-sigma-B factor antagonist Phosphoprotein%3B Positive regulator of sigma-B activity. Non- phosphorylated RsbV binds to RsbW%2C preventing its association with sigma-B. When phosphorylated%2C releases RsbW%2C which is then free to complex with and inactivate sigma-B (By similarity)%3B Belongs to the anti-sigma-factor antagonist family%3B Contains 1 STAS domain gene gene4407 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04408 S100141_04409 S100141_04409 rsbW rsbW 4160462 4160947 + Non-specific serine/threonine protein kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Serine/threonine-protein kinase%3B Transferase%3B Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein%2C RsbV. Upon phosphorylation of RsbV%2C RsbW is released and binds to sigma-B%2C thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)%3B Belongs to the anti-sigma-factor family%3B KEGG: bli:BL02207 serine/threonine-protein kinase RsbW gene gene4408 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04409 S100141_04410 S100141_04410 S100141_04410 4160913 4161704 + RNA polymerase sigma-B factor DNA-binding%3B Sigma factor%3B Stress response%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma B is not essential for sporulatio%3B rather it is required for maximal expression of ctc and csbA which are transcribed in the early stationary phase under conditions inimical to sporulation. May play a role in the ability of the bacterium to adapt to various stresses but is not essential for its survival under these conditions. Positively regulates expression of its own operon. Belongs to the sigma-70 factor family. SigB subfamily gene gene4409 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04410 S100141_04411 S100141_04411 rsbX rsbX 4161701 4162300 + Phosphoserine phosphatase Hydrolase%3B Protein phosphatase%3B Negative regulator of sigma-B activity. Dephosphorylates RsbS. Plays a role both in maintaining low sigma-B activity during growth and in reestablishing prestress sigma-B activity after induction. Could have a negative feedback role by indirectly communicating sigma-B protein levels%3B Contains 1 PPM-type phosphatase domain%3B KEGG: bli:BL02209 negative regulator of sigma-B (phosphoserine phosphatase) gene gene4410 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04411 S100141_04412 S100141_04412 S100141_04412 4162378 4164540 + uncharacterized protein Coiled coil%3B Contains 1 S1 motif domain gene gene4411 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04412 S100141_04413 S100141_04413 S100141_04413 4164590 4165147 - putative HTH-type transcriptional regulator YxbF DNA-binding%3B Repeat%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 2 HTH tetR-type DNA-binding domains gene gene4412 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04413 S100141_04414 S100141_04414 S100141_04414 4165504 4168623 + Putative membrane protein YdgH Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family. MmpL subfamily gene gene4413 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04414 S100141_04415 S100141_04415 S100141_04415 4169013 4169474 + Protein SprT-like Cytoplasm%3B Metal-binding%3B Zinc%3B Belongs to the SprT family%3B Contains 1 SprT-like domain gene gene4414 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04415 S100141_04416 S100141_04416 S100141_04416 4169591 4169665 + tRNA-Asn tRNA gene4415 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04416 S100141_04417 S100141_04417 S100141_04417 4169668 4169758 + tRNA-Ser tRNA gene4416 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04417 S100141_04418 S100141_04418 S100141_04418 4169787 4169858 + tRNA-Glu tRNA gene4417 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04418 S100141_04419 S100141_04419 S100141_04419 4169871 4169945 + tRNA-Gln tRNA gene4418 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04419 S100141_04420 S100141_04420 S100141_04420 4169954 4170029 + tRNA-Lys tRNA gene4419 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04420 S100141_04421 S100141_04421 S100141_04421 4170042 4170124 + tRNA-Leu tRNA gene4420 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04421 S100141_04422 S100141_04422 S100141_04422 4170145 4170228 + tRNA-Leu tRNA gene4421 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04422 S100141_04423 S100141_04423 S100141_04423 4170618 4170968 - hypothetical protein gene gene4422 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04423 S100141_04424 S100141_04424 S100141_04424 4170958 4171197 - putative HTH-type transcriptional regulator DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene4423 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04424 S100141_04425 S100141_04425 S100141_04425 4171835 4172863 - Fatty acid desaturase Cell membrane%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsaturated fatty acids%3B Belongs to the fatty acid desaturase family%3B KEGG: bss:BSUW23_02535 omega-6 fatty acid desaturase (delta-12 desaturase)%3B With oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water gene gene4424 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04425 S100141_04426 S100141_04426 S100141_04426 4173462 4173665 + Cold shock protein Activator%3B Cytoplasm%3B DNA-binding%3B Stress response%3B Transcription%3B Transcription regulation%3B Contains 1 CSD (cold-shock) domain gene gene4425 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04426 S100141_04427 S100141_04427 mecR mecR 4173921 4174907 - Trans-2-enoyl-CoA reductase (NADPH) Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Mitochondrion%3B NADP%3B Oxidoreductase%3B Transit peptide%3B Oxidoreductase with a preference for short and medium chain substrates%2C including trans-2-hexenoyl-CoA (C6)%2C trans-2- decenoyl-CoA (C10)%2C and trans-2-hexadecenoyl-CoA (C16). May play a role in mitochondrial fatty acid synthesis (By similarity)%3B Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily%3B KEGG: tsp:Tsp_07030 mitochondrial trans-2-enoyl-CoA reductase gene gene4426 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04427 S100141_04428 S100141_04428 S100141_04428 4174967 4175278 - hypothetical protein gene gene4427 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04428 S100141_04429 S100141_04429 S100141_04429 4175275 4175880 - uncharacterized protein gene gene4428 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04429 S100141_04430 S100141_04430 S100141_04430 4175989 4176444 + putative HTH-type transcriptional regulator YybA DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH marR-type DNA-binding domain gene gene4429 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04430 S100141_04431 S100141_04431 S100141_04431 4176469 4176987 + Spermidine/spermine N(1)-acetyltransferase Acyltransferase%3B Sporulation%3B Transferase%3B Involved in the protection against polyamine toxicity by regulating their concentration. Also could be involved in the negative control of sporulation as well as production of degradative enzymes such as alpha-amylase%2C levansucrase and alkaline phosphatase. Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to an acceptor substrate and releases both CoA and the acetylated product. It possesses N1- acetyltransferase activity toward polyamine substrates including spermidine%2C spermine%2C aminopropylcadaverine%2C norspermidine%2C homospermidine%2C N(8)-acetylspermidine%2C diaminopropane and agmatine%3B Contains 1 N-acetyltransferase domain%3B KEGG: gfo:GFO_2080 null%3B Transferring groups other than amino-acyl groups gene gene4430 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04431 S100141_04432 S100141_04432 S100141_04432 4177009 4177626 + Protease synthase and sporulation protein PAI Sporulation%3B Involved in the reduction of extracellular and cell- associated protease levels%2C as well as in the reduced levels of alpha-amylase%2C levansucrase%2C alkaline phosphatase and sporulation inhibition%2C when present in high copy number. Belongs to the PaiB family gene gene4431 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04432 S100141_04433 S100141_04433 S100141_04433 4178021 4178935 - Arginase KEGG: xfa:XF1250 arginase gene gene4432 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04433 S100141_04434 S100141_04434 S100141_04434 4179041 4179376 + putative HTH-type transcriptional regulator DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH hxlR-type DNA-binding domain gene gene4433 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04434 S100141_04435 S100141_04435 S100141_04435 4179715 4180587 + UPF0750 membrane protein YdeO Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0750 family gene gene4434 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04435 S100141_04436 S100141_04436 S100141_04436 4180686 4181135 - Cysteine/O-acetylserine efflux protein Amino-acid transport%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Exporter of O-acetylserine (OAS) and cysteine%3B Belongs to the rht family gene gene4435 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04436 S100141_04437 S100141_04437 S100141_04437 4181397 4182278 + HTH-type transcriptional regulator SoxR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcriptional repressor of soxA gene expression. Contains 1 HTH lysR-type DNA-binding domain gene gene4436 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04437 S100141_04438 S100141_04438 S100141_04438 4182360 4182581 + hypothetical protein gene gene4437 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04438 S100141_04439 S100141_04439 S100141_04439 4182762 4183988 + hypothetical protein gene gene4438 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04439 S100141_04440 S100141_04440 S100141_04440 4184084 4184866 - hypothetical protein gene gene4439 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04440 S100141_04441 S100141_04441 S100141_04441 4184992 4186374 - putative transporter YdgF Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probable amino-acid or metabolite transport protein. Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene4440 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04441 S100141_04442 S100141_04442 S100141_04442 4186776 4187411 + hypothetical protein gene gene4441 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04442 S100141_04443 S100141_04443 S100141_04443 4187604 4188239 + hypothetical protein gene gene4442 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04443 S100141_04444 S100141_04444 S100141_04444 4188581 4189078 + RNA polymerase sigma factor SigV Activator%3B DNA-binding%3B Sigma factor%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin%2C paraquat and tellurite%3B Belongs to the sigma-70 factor family. ECF subfamily gene gene4443 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04444 S100141_04445 S100141_04445 S100141_04445 4189078 4189938 + Anti-sigma-V factor RsiV Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Anti-sigma factor for SigV. Negatively regulates SigV activity through direct interaction gene gene4444 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04445 S100141_04446 S100141_04446 S100141_04446 4190169 4192049 + Putative peptidoglycan O-acetyltransferase YrhL Acyltransferase%3B Cell membrane%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Belongs to the acyltransferase 3 family%3B KEGG: mtu:Rv0111 null%3B Transferring groups other than amino-acyl groups gene gene4445 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04446 S100141_04447 S100141_04447 S100141_04447 4192274 4193443 + Bicyclomycin resistance protein Antibiotic resistance%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance. Probable membrane translocase%3B Belongs to the major facilitator superfamily. Bcr/CmlA family gene gene4446 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04447 S100141_04448 S100141_04448 S100141_04448 4193483 4196578 - Histidine kinase Alginate biosynthesis%3B ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Sensory transduction%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Member of the two-component regulatory system AlgB/KinB involved in regulation of alginate biosynthesis genes. KinB functions as a membrane-associated protein kinase that phosphorylates AlgB%2C probably in response to environmental signals. Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B Contains 1 PAC (PAS-associated C-terminal) domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: win:WPG_3498 two-component system%2C OmpR family%2C phosphate regulon sensor histidine kinase PhoR gene gene4447 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04448 S100141_04449 S100141_04449 S100141_04449 4196753 4197829 + Sensory transduction protein LytR Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system LytR/LytS that regulates genes involved in autolysis and cell wall metabolism. Regulates the activity of the cell wall-associated murein hydrolase through regulation of lrgA and lrgB (By similarity)%3B Contains 1 HTH LytTR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene4448 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04449 S100141_04450 S100141_04450 S100141_04450 4198127 4202320 + hypothetical protein gene gene4449 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04450 S100141_04451 S100141_04451 S100141_04451 4202283 4204052 + hypothetical protein gene gene4450 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04451 S100141_04452 S100141_04452 S100141_04452 4204119 4204751 + Sortase A Hydrolase%3B Protease%3B Thiol protease%3B Belongs to the peptidase C60 family%3B KEGG: bli:BL00120 sortase A gene gene4451 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04452 S100141_04453 S100141_04453 S100141_04453 4205327 4206301 + Major myo-inositol transporter IolT Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Major myo-inositol uptake transporter%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene4452 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04453 S100141_04454 S100141_04454 S100141_04454 4206292 4206747 + Solute carrier family 2%2C facilitated glucose transporter member Glycoprotein%3B Membrane%3B Phosphoprotein%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cell%3B may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney. Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family. Glucose transporter subfamily gene gene4453 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04454 S100141_04455 S100141_04455 S100141_04455 4207345 4207421 + tRNA-Arg tRNA gene4454 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04455 S100141_04456 S100141_04456 S100141_04456 4207434 4207507 + tRNA-Gly tRNA gene4455 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04456 S100141_04457 S100141_04457 S100141_04457 4207665 4209214 + 16S ribosomal RNA rRNA gene4456 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04457 S100141_04458 S100141_04458 S100141_04458 4209389 4212319 + 23S ribosomal RNA rRNA gene4457 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04458 S100141_04459 S100141_04459 S100141_04459 4212451 4212566 + 5S ribosomal RNA rRNA gene4458 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04459 S100141_04460 S100141_04460 S100141_04460 4212579 4212655 + tRNA-Met tRNA gene4459 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04460 S100141_04461 S100141_04461 S100141_04461 4212697 4212773 + tRNA-Asp tRNA gene4460 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04461 S100141_04462 S100141_04462 thiL thiL 4212968 4213951 + Thiamine-phosphate kinase ATP-binding%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Thiamine biosynthesis%3B Transferase%3B Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP)%2C the active form of vitamin B1%3B Belongs to the thiamine-monophosphate kinase family%3B KEGG: gsb:GSUB_15825 thiamine-monophosphate kinase gene gene4461 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04462 S100141_04463 S100141_04463 S100141_04463 4213948 4214436 + tRNA threonylcarbamoyladenosine biosynthesis protein TsaE ATP-binding%3B Cytoplasm%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B tRNA processing%3B Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37%2C together with TsaD and Tsa%3B this reaction does not require ATP in vitro. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway%2C possibly in regulating the core enzymatic function of TsaD. Displays ATPase activity in vitro%2C which is modulated by the oligomeric status of the protein%3B Belongs to the TsaE family gene gene4462 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04463 S100141_04464 S100141_04464 S100141_04464 4214417 4215106 + tRNA threonylcarbamoyladenosine biosynthesis protein TsaB Cytoplasm%3B tRNA processing%3B Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37%2C together with TsaD and Tsa%3B this reaction does not require ATP in vitro. TsaB seems to play an indirect role in the t(6)A biosynthesis pathway%2C possibly in regulating the core enzymatic function of TsaD%3B Belongs to the KAE1 / TsaD family. TsaB subfamily gene gene4463 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04464 S100141_04465 S100141_04465 rimI rimI 4215131 4215577 + Ribosomal-protein-alanine N-acetyltransferase Acyltransferase%3B Cytoplasm%3B Transferase%3B This enzyme acetylates the N-terminal alanine of ribosomal protein S18%3B Belongs to the acetyltransferase family. RimI subfamily%3B Contains 1 N-acetyltransferase domain%3B KEGG: bli:BL00844 ribosomal-protein-alanine N-acetyltransferase gene gene4464 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04465 S100141_04466 S100141_04466 kae1 kae1 4215567 4216592 + N(6)-L-threonylcarbamoyladenine synthase Acyltransferase%3B Cytoplasm%3B Iron%3B Metal-binding%3B Transferase%3B tRNA processing%3B Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37%2C together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction%3B Belongs to the KAE1 / TsaD family%3B KEGG: bli:BL00845 N6-L-threonylcarbamoyladenine synthase gene gene4465 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04466 S100141_04467 S100141_04467 S100141_04467 4216832 4218757 - Iron-chelate-transporting ATPase ATP-binding%3B Nucleotide-binding%3B Repeat%3B Transport%3B Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily%3B Contains 2 ABC transporter domains%3B KEGG: yee:YE5303_30631 iron complex transport system ATP-binding protein gene gene4466 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04467 S100141_04468 S100141_04468 moaC moaC 4218904 4219410 + Cyclic pyranopterin phosphate synthase Molybdenum cofactor biosynthesis%3B Together with MoaA%2C is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z)%3B Belongs to the MoaC family%3B KEGG: spoi:IMCC21906_01961 cyclic pyranopterin phosphate synthase gene gene4467 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04468 S100141_04469 S100141_04469 S100141_04469 4219414 4220061 + Redox-sensing transcriptional repressor Rex Cytoplasm%3B DNA-binding%3B NAD%3B Repressor%3B Transcription%3B Transcription regulation%3B Modulates transcription in response to changes in cellular NADH/NAD(+) redox state%3B Belongs to the transcriptional regulatory Rex family gene gene4468 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04469 S100141_04470 S100141_04470 S100141_04470 4220104 4220283 + Sec-independent protein translocase protein TatA Cell membrane%3B Membrane%3B Protein transport%3B Translocation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system%3B Belongs to the TatA/E family gene gene4469 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04470 S100141_04471 S100141_04471 S100141_04471 4220290 4221066 + Sec-independent protein translocase protein TatC Cell membrane%3B Membrane%3B Protein transport%3B Translocation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes%3B Belongs to the TatC family gene gene4470 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04471 S100141_04472 S100141_04472 S100141_04472 4221112 4221306 - putative lipoprotein YdiK Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transmembrane%3B Transmembrane helix. gene gene4471 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04472 S100141_04473 S100141_04473 S100141_04473 4221303 4222037 - Putative membrane peptidase YdiL Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Transmembrane%3B Transmembrane helix%3B May function as endopeptidase which proteolytically removes the C-terminal three residues of farnesylated peptides containing the CAAX motif where C is cysteine%2C A is an aliphatic amino acid and X is any amino acid%3B Belongs to the peptidase U48 family gene gene4472 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04473 S100141_04474 S100141_04474 S100141_04474 4222263 4222547 + 10 kDa chaperonin Chaperone%3B Cytoplasm%3B Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter%3B Belongs to the GroES chaperonin family gene gene4473 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04474 S100141_04475 S100141_04475 S100141_04475 4222592 4224226 + 60 kDa chaperonin ATP-binding%3B Chaperone%3B Cytoplasm%3B Nucleotide-binding%3B Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions%3B Belongs to the chaperonin (HSP60) family gene gene4474 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04475 S100141_04476 S100141_04476 S100141_04476 4224303 4224443 - hypothetical protein gene gene4475 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04476 S100141_04477 S100141_04477 S100141_04477 4224856 4225092 - hypothetical protein gene gene4476 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04477 S100141_04478 S100141_04478 S100141_04478 4225325 4225666 - hypothetical protein gene gene4477 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04478 S100141_04479 S100141_04479 S100141_04479 4226101 4226337 - hypothetical protein gene gene4478 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04479 S100141_04480 S100141_04480 S100141_04480 4227122 4227331 + hypothetical protein gene gene4479 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04480 S100141_04481 S100141_04481 S100141_04481 4227474 4228391 + uncharacterized protein gene gene4480 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04481 S100141_04482 S100141_04482 S100141_04482 4228509 4228958 + uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4481 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04482 S100141_04483 S100141_04483 S100141_04483 4229182 4229643 + hypothetical protein gene gene4482 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04483 S100141_04484 S100141_04484 S100141_04484 4229708 4230382 - Putative SOS response-associated peptidase YoaM Hydrolase%3B Protease%3B Belongs to the SOS response-associated peptidase family gene gene4483 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04484 S100141_04485 S100141_04485 S100141_04485 4230814 4231296 + putative HTH-type transcriptional regulator YerO DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH tetR-type DNA-binding domain gene gene4484 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04485 S100141_04486 S100141_04486 S100141_04486 4231419 4234040 + Pyruvate%2C water dikinase Transferase%3B Might catalyze the phosphorylation of pyruvate to phosphoenolpyruvate%3B Belongs to the PEP-utilizing enzyme family%3B KEGG: bli:BL01065 pyruvate%2C water dikinase gene gene4485 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04486 S100141_04487 S100141_04487 S100141_04487 4234068 4234352 - uncharacterized protein gene gene4486 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04487 S100141_04488 S100141_04488 S100141_04488 4234418 4234780 - DNA-3-methyladenine glycosylase II To M. tuberculosis Rv3073c%3B KEGG: btp:D805_0940 DNA-3-methyladenine glycosylase gene gene4487 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04488 S100141_04489 S100141_04489 S100141_04489 4234864 4235628 - putative oxidoreductase DltE Cytoplasm%3B NAD%3B Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: enr:H650_10080 uncharacterized oxidoreductase%3B Oxidoreductases gene gene4488 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04489 S100141_04490 S100141_04490 S100141_04490 4235780 4237252 + Para-nitrobenzyl esterase Hydrolase%3B Phosphoprotein%3B Serine esterase%3B Catalyzes hydrolysis of several beta-lactam antibiotic PNB esters to the corresponding free acid and PNB alcohol. Belongs to the type-B carboxylesterase/lipase family%3B KEGG: bli:BL01300 para-nitrobenzyl esterase%3B Carboxylic ester hydrolases gene gene4489 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04490 S100141_04491 S100141_04491 S100141_04491 4237277 4238554 - Minor myo-inositol transporter IolF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Minor myo-inositol uptake transporter%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene4490 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04491 S100141_04492 S100141_04492 S100141_04492 4238924 4239604 + Phage shock protein Cell inner membrane%3B Cell membrane%3B Coiled coil%3B Cytoplasm%3B Membrane%3B The phage shock protein (psp) operon (pspABCDE) may play a significant role in the competition for survival under nutrient- or energy-limited conditions. PspA negatively regulates expression of the pspABCDE promoter and of pspG through negative regulation of the psp-specific transcriptional activator PspF. Is also required for membrane integrity%2C efficient translocation and maintenance of the proton motive force (By similarity)%3B Belongs to the PspA/IM30 family gene gene4491 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04492 S100141_04493 S100141_04493 S100141_04493 4239639 4240664 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4492 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04493 S100141_04494 S100141_04494 S100141_04494 4240664 4241431 + UPF0603 protein YdjH Cell membrane%3B Membrane%3B Signal%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0603 family gene gene4493 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04494 S100141_04495 S100141_04495 S100141_04495 4241453 4242427 + uncharacterized protein gene gene4494 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04495 S100141_04496 S100141_04496 S100141_04496 4242687 4243742 + uncharacterized protein Monooxygenase%3B Oxidoreductase%3B Plasmid%3B Belongs to the bacterial luciferase oxidoreductase family%3B KEGG: ret:RHE_CH03117 null%3B Oxidoreductases gene gene4495 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04496 S100141_04497 S100141_04497 S100141_04497 4243775 4244602 - Cadmium-exporting ATPase Coiled coil%3B KEGG: cau:Caur_3747 Cd2+/Zn2+-exporting ATPase gene gene4496 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04497 S100141_04498 S100141_04498 S100141_04498 4244749 4245381 + putative membrane protein YrhP Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the rht family gene gene4497 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04498 S100141_04499 S100141_04499 S100141_04499 4245576 4246220 + hypothetical protein gene gene4498 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04499 S100141_04500 S100141_04500 S100141_04500 4246236 4247393 + Putative lipid II flippase Cell cycle%3B Cell division%3B Cell inner membrane%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Peptidoglycan synthesis%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Essential cell division protein. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane%3B Belongs to the SEDS family. FtsW subfamily gene gene4499 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04500 S100141_04501 S100141_04501 S100141_04501 4247390 4248538 + Putative lipid II flippase FtsW Cell cycle%3B Cell division%3B Cell inner membrane%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Peptidoglycan synthesis%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Essential cell division protein. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane%3B Belongs to the SEDS family. FtsW subfamily gene gene4500 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04501 S100141_04502 S100141_04502 S100141_04502 4249227 4249652 - hypothetical protein gene gene4501 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04502 S100141_04503 S100141_04503 S100141_04503 4249747 4250694 + putative HTH-type transcriptional regulator YobV Cytoplasm%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH deoR-type DNA-binding domain gene gene4502 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04503 S100141_04504 S100141_04504 S100141_04504 4250972 4251649 + hypothetical protein gene gene4503 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04504 S100141_04505 S100141_04505 S100141_04505 4251721 4253100 + Peptidoglycan-N-acetylmuramic acid deacetylase PdaC Cell membrane%3B Hydrolase%3B Membrane%3B Metal-binding%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the deacetylation of N-acetylmuramic acid (MurNAc) residues in peptidoglycan%2C a modification that confers resistance to lysosyme. Is not able to deacetylate N- acetylglucosamine (GlcNAc) residues in peptidoglycan%2C but can deacylate chitin oligomers such as GlcNAc4 and GlcNAc5. Is essentially not active toward chitosan (partially deacetylated GlcNAc polymer) and has very low activity toward chitin (GlcNAc polymer). Does not deacetylate GlcNAc%3B Belongs to the polysaccharide deacetylase family%3B KEGG: baci:B1NLA3E_02370 peptidoglycan-N-acetylmuramic acid deacetylase%3B In linear amides gene gene4504 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04505 S100141_04506 S100141_04506 amyA amyA 4253229 4254767 + Alpha-amylase Calcium%3B Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Metal-binding%3B Signal%3B Belongs to the glycosyl hydrolase 13 family%3B KEGG: bli:BL00499 alpha-amylase gene gene4505 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04506 S100141_04507 S100141_04507 S100141_04507 4254930 4255880 + putative HTH-type transcriptional regulator YvdE DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH lacI-type DNA-binding domain gene gene4506 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04507 S100141_04508 S100141_04508 S100141_04508 4256000 4257760 + Glucan 1%2C4-alpha-maltohydrolase Carbohydrate metabolism%3B Cytoplasm%3B Glycosidase%3B Hydrolase%3B Hydrolyzes beta-cyclodextrin to maltose and glucose%2C soluble starch to maltose and glucose%2C and pullulan to panose with trace amounts of maltose and glucose. It is also able to hydrolyze acarbose. Can also exhibit a transglycosylation activity transferring glucose or maltose to another moiety of sugars by forming alpha-(1%2C6)- and alpha-(1%2C3)-glycosidic linkages upon the hydrolysis of substrate at concentrations of 5%25 or higher%3B Belongs to the glycosyl hydrolase 13 family. BbmA subfamily%3B KEGG: bld:BLi00658 null gene gene4507 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04508 S100141_04509 S100141_04509 S100141_04509 4257855 4259108 + Maltodextrin-binding protein MdxE Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Polysaccharide transport%3B Signal%3B Sugar transport%3B Transport%3B Part of the ABC transporter complex involved in maltodextrin import. Binds maltodextrin. Can also bind maltose with low affinity%2C but is not involved in its uptake%3B Belongs to the bacterial solute-binding protein 1 family gene gene4508 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04509 S100141_04510 S100141_04510 S100141_04510 4259150 4260457 + Maltodextrin transport system permease protein MalC Cell membrane%3B Membrane%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system for maltodextri%3B probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene4509 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04510 S100141_04511 S100141_04511 S100141_04511 4260458 4261309 + Maltodextrin transport system permease protein MdxG Cell membrane%3B Membrane%3B Polysaccharide transport%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex involved in maltodextrin import. Probably responsible for the translocation of the substrate across the membrane (Probable)%3B Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene4510 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04511 S100141_04512 S100141_04512 S100141_04512 4261314 4262195 + Putative maltodextrin utilization protein YvdJ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4511 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04512 S100141_04513 S100141_04513 mapA mapA 4262173 4264455 + Maltose phosphorylase Carbohydrate metabolism%3B Glycosyltransferase%3B Transferase%3B Catalyzes the phosphorolysis of maltose%2C leading to the formation of glucose and glucose 1-P%3B Belongs to the glycosyl hydrolase 65 family%3B KEGG: bsu:BSU34570 maltose phosphorylase gene gene4512 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04513 S100141_04514 S100141_04514 S100141_04514 4264452 4266158 + Alpha-glucosidase Cytoplasm%3B Glycosidase%3B Hydrolase%3B Hydrolyzes various disaccharides such as sucrose%2C maltose%2C and isomaltose with different efficiencies. Also hydrolyzes longer maltodextrins from maltotriose up to maltohexaose%2C but not maltoheptaose%2C palatinose%2C isomaltotriose%2C or isomaltotetraose. Belongs to the glycosyl hydrolase 13 family%3B KEGG: rah:Rahaq_2679 alpha-glucosidase gene gene4513 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04514 S100141_04515 S100141_04515 S100141_04515 4266155 4266463 + Beta-phosphoglucomutase Carbohydrate metabolism%3B Cytoplasm%3B Isomerase%3B Magnesium%3B Metal-binding%3B Phosphoprotein%3B Catalyzes the interconversion of D-glucose 1-phosphate (G1P) and D-glucose 6-phosphate (G6P)%2C and forming beta-D-glucose 1%2C6-(bis)phosphate (beta-G16P) as an intermediate. The beta- phosphoglucomutase (Beta-PGM) acts on the beta-C(1) anomer of G1P. It plays a key role in the regulation of the flow of carbohydrate intermediates in glycolysis and the formation of the sugar nucleotide UDP-glucose (By similarity)%3B Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family%3B overlaps another CDS with the same product name gene gene4514 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04515 S100141_04516 S100141_04516 pgmB pgmB 4266460 4266834 + Beta-phosphoglucomutase Carbohydrate metabolism%3B Cytoplasm%3B Isomerase%3B Magnesium%3B Metal-binding%3B Phosphoprotein%3B Catalyzes the interconversion of D-glucose 1-phosphate (G1P) and D-glucose 6-phosphate (G6P)%2C forming beta-D-glucose 1%2C6- (bis)phosphate (beta-G16P) as an intermediate. The beta- phosphoglucomutase (Beta-PGM) acts on the beta-C(1) anomer of G1P. Glucose or lactose are used in preference to maltose%2C which is only utilized after glucose or lactose has been exhausted. It plays a key role in the regulation of the flow of carbohydrate intermediates in glycolysis and the formation of the sugar nucleotide UDP-glucose%3B Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family%3B KEGG: bli:BL00490 beta-phosphoglucomutase%3B overlaps another CDS with the same product name gene gene4515 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04516 S100141_04517 S100141_04517 S100141_04517 4267117 4268370 - Tyrosine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B RNA-binding%3B Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)%3B Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily%3B Contains 1 S4 RNA-binding domain%3B KEGG: bli:BL00484 tyrosyl-tRNA synthetase gene gene4516 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04517 S100141_04518 S100141_04518 S100141_04518 4268626 4269132 - putative HTH-type transcriptional regulator YwaE DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH marR-type DNA-binding domain gene gene4517 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04518 S100141_04519 S100141_04519 S100141_04519 4269269 4269835 - hypothetical protein gene gene4518 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04519 S100141_04520 S100141_04520 S100141_04520 4269832 4270224 - hypothetical protein gene gene4519 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04520 S100141_04521 S100141_04521 S100141_04521 4270426 4270806 + uncharacterized protein gene gene4520 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04521 S100141_04522 S100141_04522 S100141_04522 4270863 4271882 + uncharacterized protein Signal. gene gene4521 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04522 S100141_04523 S100141_04523 S100141_04523 4271925 4272917 - uncharacterized protein gene gene4522 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04523 S100141_04524 S100141_04524 S100141_04524 4273010 4273312 - hypothetical protein gene gene4523 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04524 S100141_04525 S100141_04525 S100141_04525 4273444 4273701 - hypothetical protein gene gene4524 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04525 S100141_04526 S100141_04526 S100141_04526 4273989 4274537 + Signal peptidase I Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Essential for cell viability%3B Belongs to the peptidase S26 family%3B KEGG: bli:BL00487 signal peptidase I gene gene4525 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04526 S100141_04527 S100141_04527 S100141_04527 4274989 4275273 + hypothetical protein gene gene4526 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04527 S100141_04528 S100141_04528 codA codA 4275592 4276236 + Cytosine deaminase Lyase%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: sfa:Sfla_2548 cytosine deaminase gene gene4527 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04528 S100141_04529 S100141_04529 S100141_04529 4276279 4277151 - Lactose operon transcription activator Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Transcriptional regulator of the lacPH genes for lactose utilization. Contains 1 HTH araC/xylS-type DNA-binding domain gene gene4528 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04529 S100141_04530 S100141_04530 S100141_04530 4277260 4278801 - Spore coat protein Sporulation%3B Involved in brown pigmentation during sporogenesis. To S. antibioticus phenoxazinone synthase (PhsA) gene gene4529 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04530 S100141_04531 S100141_04531 S100141_04531 4279073 4280083 + hypothetical protein gene gene4530 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04531 S100141_04532 S100141_04532 S100141_04532 4280121 4280618 - hypothetical protein gene gene4531 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04532 S100141_04533 S100141_04533 S100141_04533 4281265 4282137 + putative transporter YeaB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the cation diffusion facilitator (CDF) transporter (TC 2. A. 4) family gene gene4532 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04533 S100141_04534 S100141_04534 S100141_04534 4282297 4283259 + uncharacterized protein ATP-binding%3B Nucleotide-binding%3B Belongs to the MoxR family%3B KEGG: bsu:BSU06330 MoxR-like ATPase%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances%3B overlaps another CDS with the same product name gene gene4533 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04534 S100141_04535 S100141_04535 S100141_04535 4283259 4284470 + uncharacterized protein overlaps another CDS with the same product name gene gene4534 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04535 S100141_04536 S100141_04536 S100141_04536 4284475 4286700 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4535 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04536 S100141_04537 S100141_04537 guaA guaA 4286889 4288430 + GMP synthase (glutamine-hydrolyzing) ATP-binding%3B Glutamine amidotransferase%3B GMP biosynthesis%3B Ligase%3B Nucleotide-binding%3B Purine biosynthesis%3B Catalyzes the synthesis of GMP from XMP%3B Contains 1 glutamine amidotransferase type-1 domain%3B Contains 1 GMPS ATP-PPase (ATP pyrophosphatase) domain%3B KEGG: bsu:BSU06360 GMP synthase (glutamine-hydrolysing) gene gene4536 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04537 S100141_04538 S100141_04538 S100141_04538 4288850 4290376 + Putative permease Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2. A. 1. 40) subfamily gene gene4537 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04538 S100141_04539 S100141_04539 S100141_04539 4290593 4291351 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4538 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04539 S100141_04540 S100141_04540 S100141_04540 4291473 4291661 + hypothetical protein gene gene4539 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04540 S100141_04541 S100141_04541 S100141_04541 4291847 4292401 + UPF0316 protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0316 family gene gene4540 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04541 S100141_04542 S100141_04542 S100141_04542 4292401 4292598 + uncharacterized protein gene gene4541 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04542 S100141_04543 S100141_04543 purE purE 4292916 4293404 + 5-(carboxyamino)imidazole ribonucleotide mutase ATP-binding%3B Decarboxylase%3B Lyase%3B Nucleotide-binding%3B Phosphoprotein%3B Purine biosynthesis%3B In the C-terminal sectio%3B belongs to the AIR carboxylase family. Class I subfamily%3B Contains 1 ATP-grasp domain%3B KEGG: sml:Smlt1613 5-(carboxyamino)imidazole ribonucleotide mutase gene gene4542 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04543 S100141_04544 S100141_04544 purK purK 4293388 4294539 + 5-(carboxyamino)imidazole ribonucleotide synthase ATP-binding%3B Ligase%3B Nucleotide-binding%3B Purine biosynthesis%3B Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)%3B Belongs to the PurK/PurT family%3B Contains 1 ATP-grasp domain%3B KEGG: bld:BLi00694 5-(carboxyamino)imidazole ribonucleotide synthase gene gene4543 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04544 S100141_04545 S100141_04545 purB purB 4294536 4295831 + Adenylosuccinate lyase Lyase%3B Purine biosynthesis%3B Influences the affinity of glutamyl--tRNA ligase for its substrates and increases its thermostability. Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily%3B KEGG: afe:Lferr_1990 adenylosuccinate lyase gene gene4544 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04545 S100141_04546 S100141_04546 purC purC 4295906 4296622 + Phosphoribosylaminoimidazolesuccinocarboxamide synthase ATP-binding%3B Ligase%3B Nucleotide-binding%3B Purine biosynthesis%3B Belongs to the SAICAR synthetase family%3B KEGG: bsu:BSU06450 phosphoribosylaminoimidazole-succinocarboxamide synthase gene gene4545 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04546 S100141_04547 S100141_04547 purL purL 4296624 4296878 + Phosphoribosylformylglycinamidine synthase ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Purine biosynthesis%3B Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL%3B Belongs to the PurS family%3B KEGG: bsu:BSU06460 phosphoribosylformylglycinamidine synthase%3B overlaps another CDS with the same product name gene gene4546 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04547 S100141_04548 S100141_04548 S100141_04548 4296875 4297558 + Phosphoribosylformylglycinamidine synthase ATP-binding%3B Cytoplasm%3B Glutamine amidotransferase%3B Hydrolase%3B Ligase%3B Nucleotide-binding%3B Purine biosynthesis%3B Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: bsu:BSU06470 phosphoribosylformylglycinamidine synthase%3B overlaps another CDS with the same product name gene gene4547 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04548 S100141_04549 S100141_04549 S100141_04549 4297542 4299770 + Phosphoribosylformylglycinamidine synthase ATP-binding%3B Cytoplasm%3B Ligase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Purine biosynthesis%3B Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL%3B Belongs to the FGAMS family%3B KEGG: bsu:BSU06480 phosphoribosylformylglycinamidine synthase%3B overlaps another CDS with the same product name gene gene4548 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04549 S100141_04550 S100141_04550 purF purF 4299746 4301176 + Amidophosphoribosyltransferase 4Fe-4S%3B Allosteric enzyme%3B Glutamine amidotransferase%3B Glycosyltransferase%3B Iron%3B Iron-sulfur%3B Magnesium%3B Metal-binding%3B Purine biosynthesis%3B Transferase%3B Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine%3B In the C-terminal sectio%3B belongs to the purine/pyrimidine phosphoribosyltransferase family%3B Contains 1 glutamine amidotransferase type-2 domain%3B KEGG: bsu:BSU06490 amidophosphoribosyltransferase gene gene4549 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04550 S100141_04551 S100141_04551 purM purM 4301297 4302340 + Phosphoribosylformylglycinamidine cyclo-ligase ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Purine biosynthesis%3B Belongs to the AIR synthase family%3B KEGG: bld:BLi00701 phosphoribosylformylglycinamidine cyclo-ligase gene gene4550 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04551 S100141_04552 S100141_04552 purN purN 4302337 4302924 + Phosphoribosylglycinamide formyltransferase Purine biosynthesis%3B Transferase%3B Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR)%2C producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate%3B Belongs to the GART family%3B KEGG: bsu:BSU06510 phosphoribosylglycinamide formyltransferase 1 gene gene4551 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04552 S100141_04553 S100141_04553 purH purH 4302921 4304459 + Phosphoribosylaminoimidazolecarboxamide formyltransferase Hydrolase%3B Multifunctional enzyme%3B Purine biosynthesis%3B Transferase%3B Belongs to the PurH family%3B KEGG: bpn:BPEN_575 phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase gene gene4552 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04553 S100141_04554 S100141_04554 purD purD 4304473 4305741 + Phosphoribosylamine--glycine ligase ATP-binding%3B Ligase%3B Magnesium%3B Manganese%3B Metal-binding%3B Nucleotide-binding%3B Purine biosynthesis%3B Belongs to the GARS family%3B Contains 1 ATP-grasp domain%3B KEGG: pbr:PB2503_12869 phosphoribosylamine--glycine ligase gene gene4553 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04554 S100141_04555 S100141_04555 S100141_04555 4306061 4306369 - hypothetical protein gene gene4554 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04555 S100141_04556 S100141_04556 S100141_04556 4306508 4307731 + Putative cytochrome P450 YjiB Heme%3B Iron%3B Metal-binding%3B Monooxygenase%3B Oxidoreductase%3B Belongs to the cytochrome P450 family%3B KEGG: bay:RBAM_012290 null%3B Acting on paired donors%2C with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O(2) gene gene4555 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04556 S100141_04557 S100141_04557 S100141_04557 4308305 4308415 + hypothetical protein gene gene4556 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04557 S100141_04558 S100141_04558 S100141_04558 4308427 4308873 + putative lipoprotein YybP Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal. gene gene4557 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04558 S100141_04559 S100141_04559 S100141_04559 4308976 4309392 + hypothetical protein gene gene4558 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04559 S100141_04560 S100141_04560 S100141_04560 4309471 4309701 - putative membrane protein YezF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4559 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04560 S100141_04561 S100141_04561 S100141_04561 4309827 4311566 + Adenine deaminase Hydrolase%3B Phosphoprotein%3B Belongs to the adenine deaminase family%3B KEGG: bli:BL01492 adenine deaminase gene gene4560 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04561 S100141_04562 S100141_04562 S100141_04562 4311592 4312581 + Putative lipoprotein YerB Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Phosphoprotein%3B Signal. gene gene4561 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04562 S100141_04563 S100141_04563 S100141_04563 4312584 4312895 + uncharacterized protein gene gene4562 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04563 S100141_04564 S100141_04564 pcrB pcrB 4313046 4313732 + Heptaprenylglyceryl phosphate synthase Lipid biosynthesis%3B Lipid metabolism%3B Magnesium%3B Metal-binding%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepP%3B 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P)%2C producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales%3B Belongs to the GGGP/HepGP synthase family%3B KEGG: bsu:BSU06600 putative glycerol-1-phosphate prenyltransferase%3B Transferring alkyl or aryl groups%2C other than methyl groups gene gene4563 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04564 S100141_04565 S100141_04565 S100141_04565 4313792 4316011 + DNA helicase ATP-binding%3B DNA damage%3B DNA repair%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B DNA helicase used for plasmid rolling-circle replication and also involved in UV repair. Belongs to the helicase family. UvrD subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: bsu:BSU06610 DNA helicase II / ATP-dependent DNA helicase PcrA gene gene4564 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04565 S100141_04566 S100141_04566 ligA ligA 4316045 4318048 + DNA ligase (NAD(+)) DNA damage%3B DNA repair%3B DNA replication%3B Ligase%3B Magnesium%3B Manganese%3B Metal-binding%3B NAD%3B Zinc%3B DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA%3B Belongs to the NAD-dependent DNA ligase family. LigA subfamily%3B Contains 1 BRCT domain%3B KEGG: bli:BL00589 DNA ligase (NAD+) gene gene4565 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04566 S100141_04567 S100141_04567 S100141_04567 4318064 4319344 + putative lipoprotein YerH Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal. gene gene4566 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04567 S100141_04568 S100141_04568 S100141_04568 4319515 4320504 + hypothetical protein gene gene4567 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04568 S100141_04569 S100141_04569 S100141_04569 4320598 4321524 + uncharacterized protein gene gene4568 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04569 S100141_04570 S100141_04570 S100141_04570 4321625 4321990 + hypothetical protein gene gene4569 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04570 S100141_04571 S100141_04571 S100141_04571 4322003 4322362 + uncharacterized protein gene gene4570 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04571 S100141_04572 S100141_04572 S100141_04572 4322507 4323808 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4571 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04572 S100141_04573 S100141_04573 S100141_04573 4323835 4324719 + Aryldialkylphosphatase Cobalt%3B Hydrolase%3B Iron%3B Metal-binding%3B Has a low paraoxonase activity. Also active%2C but with a lower activity%2C against other organo-phosphorus insecticides such as Dursban%2C Coumaphos%2C pNP-butanoate or parathion%3B Belongs to the phosphotriesterase family gene gene4572 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04573 S100141_04574 S100141_04574 S100141_04574 4324716 4325864 + Cysteine desulfurase KEGG: frf:LO80_09340 cysteine desulfurase / selenocysteine lyase gene gene4573 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04574 S100141_04575 S100141_04575 S100141_04575 4325857 4327083 + Phosphopentomutase Manganese%3B Metal-binding%3B Belongs to the phosphopentomutase family%3B KEGG: aac:Aaci_1749 phosphopentomutase gene gene4574 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04575 S100141_04576 S100141_04576 S100141_04576 4327083 4328234 + uncharacterized protein gene gene4575 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04576 S100141_04577 S100141_04577 S100141_04577 4328374 4329102 + Glucosamine-6-phosphate deaminase Carbohydrate metabolism%3B Hydrolase%3B Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion%3B Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily%3B KEGG: bli:BL00599 glucosamine-6-phosphate deaminase gene gene4576 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04577 S100141_04578 S100141_04578 S100141_04578 4329418 4330110 - Protein SapB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the MgtC/SapB family gene gene4577 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04578 S100141_04579 S100141_04579 S100141_04579 4330334 4331815 - Osmoregulated proline transporter OpuE Amino-acid transport%3B Cell membrane%3B Membrane%3B Stress response%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Catalyzes the uptake of extracellular proline under high-osmolarity growth conditions. Essential for the use of proline present in the environment as an osmoprotectant%3B Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene4578 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04579 S100141_04580 S100141_04580 gatC gatC 4332257 4332547 + Asparaginyl-tRNA synthase (glutamine-hydrolyzing) ATP-binding%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)%3B Belongs to the GatC family%3B KEGG: mmn:midi_00552 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C gene gene4579 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04580 S100141_04581 S100141_04581 gatA gatA 4332569 4334026 + Asparaginyl-tRNA synthase (glutamine-hydrolyzing) ATP-binding%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)%3B Belongs to the amidase family. GatA subfamily%3B KEGG: bsu:BSU06680 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A gene gene4580 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04581 S100141_04582 S100141_04582 gatB gatB 4334040 4335470 + Asparaginyl-tRNA synthase (glutamine-hydrolyzing) ATP-binding%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)%3B Belongs to the GatB/GatE family. GatB subfamily%3B KEGG: pae:PA4484 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B gene gene4581 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04582 S100141_04583 S100141_04583 S100141_04583 4335655 4335957 + hypothetical protein gene gene4582 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04583 S100141_04584 S100141_04584 S100141_04584 4335954 4336235 + hypothetical protein gene gene4583 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04584 S100141_04585 S100141_04585 gmuG gmuG 4336310 4337392 - Mannan endo-1%2C4-beta-mannosidase Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Polysaccharide degradation%3B Secreted%3B Signal%3B Involved in the degradation of glucomannan. Catalyzes the endo hydrolysis of beta-1%2C4-linked mannan%2C galactomannan and glucomannan%3B Belongs to the glycosyl hydrolase 26 family%3B Contains 1 GH26 (glycosyl hydrolase family 26) domain%3B KEGG: bli:BL05063 mannan endo-1%2C4-beta-mannosidase gene gene4584 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04585 S100141_04586 S100141_04586 S100141_04586 4337517 4338365 - putative HTH-type transcriptional regulator YerO DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH tetR-type DNA-binding domain gene gene4585 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04586 S100141_04587 S100141_04587 S100141_04587 4338510 4341668 + Swarming motility protein SwrC Antibiotic resistance%3B Required for self-resistance to surfactin%2C an antimicrobial lipopeptide surfactant produced by B. subtilis. Also required for swarming motility%3B Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family gene gene4586 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04587 S100141_04588 S100141_04588 S100141_04588 4341815 4342015 + hypothetical protein gene gene4587 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04588 S100141_04589 S100141_04589 S100141_04589 4342105 4342647 - Ribosomal-protein-alanine N-acetyltransferase Acyltransferase%3B Cytoplasm%3B Transferase%3B This enzyme acetylates the N-terminal alanine of ribosomal protein S5%3B Belongs to the acetyltransferase family. RimJ subfamily%3B Contains 1 N-acetyltransferase domain%3B KEGG: bli:BL02628 ribosomal-protein-alanine N-acetyltransferase gene gene4588 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04589 S100141_04590 S100141_04590 iunH iunH 4342661 4343614 - Purine nucleosidase KEGG: bli:BL02627 purine nucleosidase gene gene4589 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04590 S100141_04591 S100141_04591 S100141_04591 4343814 4344728 + Diacylglycerol kinase (ATP) ATP-binding%3B Kinase%3B Lipid biosynthesis%3B Lipid metabolism%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid. Is a key enzyme involved in the production of lipoteichoic acid by reintroducing DAG formed from the breakdown of membrane phospholipids into the phosphatidylglycerol biosynthetic pathway. Is more active toward long-chain DAG compared with short-chain DAG. Is not able to phosphorylate substrates other than DAG%2C such as monoacylglycerol%2C ceramide%2C undecaprenol%2C phosphatidylinositol%2C or sphingosine%3B Belongs to the diacylglycerol/lipid kinase family%3B Contains 1 DAGKc domain%3B KEGG: bsu:BSU06720 diacylglycerol kinase (ATP) gene gene4590 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04591 S100141_04592 S100141_04592 rumA rumA 4344777 4346153 + 23S rRNA (uracil(1939)-C(5))-methyltransferase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family%3B Contains 1 TRAM domain%3B KEGG: bli:BL02629 23S rRNA (uracil1939-C5)-methyltransferase gene gene4591 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04592 S100141_04593 S100141_04593 S100141_04593 4345981 4347633 - uncharacterized protein Coiled coil%3B DNA-binding%3B Contains 1 recombinase DNA-binding domain gene gene4592 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04593 S100141_04594 S100141_04594 S100141_04594 4347630 4347794 - hypothetical protein gene gene4593 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04594 S100141_04595 S100141_04595 S100141_04595 4348453 4349454 + hypothetical protein gene gene4594 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04595 S100141_04596 S100141_04596 S100141_04596 4349554 4350000 - hypothetical protein gene gene4595 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04596 S100141_04597 S100141_04597 S100141_04597 4350268 4350861 + hypothetical protein gene gene4596 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04597 S100141_04598 S100141_04598 S100141_04598 4350854 4352383 + Site-specific DNA-methyltransferase (adenine-specific) Methyltransferase%3B Plasmid%3B Restriction system%3B S-adenosyl-L-methionine%3B Transferase%3B Methylation of specific adenine residue%3B required for both restriction and modification activities (By similarity). The EcoR124/3 I enzyme recognizes 5'-GAAN(7)RTCG-3'%3B Belongs to the N(4)/N(6)-methyltransferase family%3B KEGG: bag:Bcoa_0278 type I restriction enzyme M protein gene gene4597 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04598 S100141_04599 S100141_04599 S100141_04599 4352408 4353256 + DNA-damage-inducible protein gene gene4598 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04599 S100141_04600 S100141_04600 hsdS hsdS 4353327 4354445 + Type I site-specific deoxyribonuclease Coiled coil%3B DNA-binding%3B Repeat%3B Restriction system%3B The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease%2C binding to the same target sequence but cutting the DNA some distance from this site. Whether the DNA is cut or modified depends on the methylation state of the target sequence. When the target site is unmodified%2C the DNA is cut. When the target site is hemimethylated%2C the complex acts as a maintenance MTase modifying the DNA so that both strands become methylated. Subunit S dictates DNA sequences specificity (By similarity)%3B Belongs to the type-I restriction system S methylase family%3B KEGG: fpz:LA55_272 type I restriction enzyme%2C S subunit gene gene4599 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04600 S100141_04601 S100141_04601 hsdR hsdR 4354489 4357596 + Type I site-specific deoxyribonuclease To M. jannaschii MJ1214%3B KEGG: bag:Bcoa_0280 type I restriction enzyme%2C R subunit gene gene4600 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04601 S100141_04602 S100141_04602 S100141_04602 4357610 4358335 + hypothetical protein gene gene4601 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04602 S100141_04603 S100141_04603 S100141_04603 4358566 4359195 + Endoribonuclease EndoA Endonuclease%3B Hydrolase%3B Nuclease%3B RNA-binding%3B Toxin%3B Toxic component of a type II toxin-antitoxin (TA) module. Specific for 5'-UACAU-3' sequences%2C cleaving after the first U (PubMed:21763692). Yields cleavage products with 3' phosphate and 5' hydroxyl groups (PubMed:15882409). Cannot digest substrate with a UUdUACAUAA cleavage site (PubMed:24120662). Overexpression is toxic for cell growth (shown in E. coli)%2C probably by inhibiting protein synthesis through the cleavage of single-stranded RNA. The toxicity is reversed by the antitoxin EndoAI. Toxin activity cannot be inhibited by MazE from E. coli. The EndoA-EndoAI complex does not seem to bind its own promoter (PubMed:24120662)%3B Belongs to the PemK/MazF family%3B KEGG: lcn:C270_06880 mRNA interferase MazF%3B Acting on ester bonds gene gene4602 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04603 S100141_04604 S100141_04604 S100141_04604 4359454 4359657 - hypothetical protein gene gene4603 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04604 S100141_04605 S100141_04605 S100141_04605 4359732 4360847 + hypothetical protein gene gene4604 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04605 S100141_04606 S100141_04606 S100141_04606 4360958 4361290 + hypothetical protein gene gene4605 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04606 S100141_04607 S100141_04607 S100141_04607 4361260 4362120 + putative transposase-like protein DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene4606 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04607 S100141_04608 S100141_04608 S100141_04608 4362607 4364472 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Kinase%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in beta-glucoside transport (By similarity)%3B Contains 1 PTS EIIA type-1 domain%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bpu:BPUM_3644 PTS system%2C beta-glucosides-specific IIA component gene gene4607 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04608 S100141_04609 S100141_04609 S100141_04609 4364475 4365944 + 6-phospho-beta-glucosidase Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P)%2C phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. BglA and BglH are the major proteins contributing to hydrolysis of MUG-P by extracts of late-exponential-phase or stationary-phase B. subtilis cells%3B Belongs to the glycosyl hydrolase 1 family%3B KEGG: bld:BLi00749 6-phospho-beta-glucosidase gene gene4608 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04609 S100141_04610 S100141_04610 S100141_04610 4365974 4366822 + PtsGHI operon antiterminator Activator%3B Phosphoprotein%3B Repeat%3B RNA-binding%3B Transcription%3B Transcription regulation%3B Mediates the positive regulation of the glucose PTS operon (ptsGHI) by functioning as an antiterminator factor of transcription via its interaction with the RNA-antiterminator (RAT) sequence located upstream of the ptsG gene. The RNA-binding domain of GlcT directly binds to the RNA antiterminator (RAT) sequence and prevents transcriptional termination. GlcT binding requires two identical and nearly symmetrical triple base pairings in the RAT sequence%3B Belongs to the transcriptional antiterminator BglG family. GlcT subfamily%3B Contains 2 PRD domains gene gene4609 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04610 S100141_04611 S100141_04611 S100141_04611 4367070 4368182 + Response regulator aspartate phosphatase Hydrolase%3B Protein phosphatase%3B Repeat%3B TPR repeat%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bsu:BSU18910 response regulator aspartate phosphatase K%3B Acting on ester bonds gene gene4610 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04611 S100141_04612 S100141_04612 S100141_04612 4368179 4368301 + hypothetical protein gene gene4611 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04612 S100141_04613 S100141_04613 S100141_04613 4368467 4369225 + hypothetical protein gene gene4612 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04613 S100141_04614 S100141_04614 S100141_04614 4369637 4370356 + putative transcriptional regulatory protein Cytoplasm%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Belongs to the TACO1 family gene gene4613 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04614 S100141_04615 S100141_04615 S100141_04615 4370513 4370722 + putative HTH-type transcriptional regulator DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene4614 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04615 S100141_04616 S100141_04616 S100141_04616 4370715 4371029 + hypothetical protein gene gene4615 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04616 S100141_04617 S100141_04617 S100141_04617 4371187 4372644 + Aldehyde dehydrogenase (NAD(+)) NAD%3B Oxidoreductase%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: bli:BL02341 aldehyde dehydrogenase (NAD+) gene gene4616 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04617 S100141_04618 S100141_04618 S100141_04618 4372661 4373512 + Putative sensory transducer protein YfmS Transducer%3B Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. Attractants increase the level of methylation while repellents decrease the level of methylation (By similarity)%3B Contains 1 methyl-accepting transducer domain gene gene4617 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04618 S100141_04619 S100141_04619 S100141_04619 4373658 4375082 + Sodium-dependent dicarboxylate transporter SdcS Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mediates the transport of the dicarboxylates fumarate%2C malate%2C and succinate across the cytoplasmic membrane via a Na(+)- electrochemical gradient%3B Belongs to the SLC13A/DASS transporter (TC 2. A. 47) family. NADC subfamily gene gene4618 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04619 S100141_04620 S100141_04620 S100141_04620 4375167 4375685 + putative ABC transporter ATP-binding protein YfmR ATP-binding%3B Coiled coil%3B Hydrolase%3B Nucleotide-binding%3B Repeat%3B Transport%3B Belongs to the ABC transporter superfamily%3B Contains 2 ABC transporter domains gene gene4619 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04620 S100141_04621 S100141_04621 S100141_04621 4375709 4377055 + ABC transporter F family member ATP-binding%3B Nucleotide-binding%3B Repeat%3B Transport%3B Ubl conjugation%3B Belongs to the ABC transporter superfamily. ABCF family. EF3 (TC 3. A. 1. 121) subfamily%3B Contains 2 ABC transporter domains gene gene4620 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04621 S100141_04622 S100141_04622 gch4 gch4 4377224 4378126 - GTP cyclohydrolase I Hydrolase%3B Converts GTP to 7%2C8-dihydroneopterin triphosphate%3B Belongs to the GTP cyclohydrolase IV family%3B KEGG: bli:BL02349 GTP cyclohydrolase I gene gene4621 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04622 S100141_04623 S100141_04623 S100141_04623 4378259 4378510 + Baeyer-Villiger flavin-containing monooxygenase FAD%3B Flavoprotein%3B Monooxygenase%3B NADP%3B Oxidoreductase%3B Catalyzes a Baeyer-Villiger oxidation reaction%2C i. e. the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl%2C which converts ketones to esters or lactones using NADPH and/or NADH as an electron donor%3B overlaps another CDS with the same product name gene gene4622 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04623 S100141_04624 S100141_04624 S100141_04624 4378507 4379370 + Baeyer-Villiger flavin-containing monooxygenase FAD%3B Flavoprotein%3B Monooxygenase%3B NADP%3B Oxidoreductase%3B Catalyzes a Baeyer-Villiger oxidation reaction%2C i. e. the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl%2C which converts ketones to esters or lactones using NADPH and/or NADH as an electron donor%3B overlaps another CDS with the same product name gene gene4623 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04624 S100141_04625 S100141_04625 S100141_04625 4379394 4381037 + Ferrous iron transport protein B like protein ATP-binding%3B Cell inner membrane%3B Cell membrane%3B GTP-binding%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B It seems that the Fe(2+) uptake in C. jejuni cannot be attributed to FeoB%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. FeoB GTPase (TC 9. A. 8) family%3B Contains 1 FeoB-type G (guanine nucleotide-binding) domain gene gene4624 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04625 S100141_04626 S100141_04626 S100141_04626 4381103 4382305 + Putative metal chaperone YciC Chaperone%3B GTP-binding%3B Nucleotide-binding%3B Zinc%3B May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc%3B Belongs to the SIMIBI class G3E GTPase family. CobW subfamily%3B Contains 1 cobW C-terminal domain gene gene4625 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04626 S100141_04627 S100141_04627 S100141_04627 4382474 4382587 + hypothetical protein gene gene4626 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04627 S100141_04628 S100141_04628 bioW bioW 4382569 4383258 + 6-carboxyhexanoate--CoA ligase ATP-binding%3B Biotin biosynthesis%3B Ligase%3B Magnesium%3B Nucleotide-binding%3B Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP%3B Belongs to the BioW family%3B KEGG: bli:BL02411 6-carboxyhexanoate--CoA ligase gene gene4627 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04628 S100141_04629 S100141_04629 S100141_04629 4383239 4384585 + Lysine--8-amino-7-oxononanoate transaminase Aminotransferase%3B Biotin biosynthesis%3B Cytoplasm%3B Pyridoxal phosphate%3B S-adenosyl-L-methionine%3B Transferase%3B Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7%2C8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor%3B Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily%3B KEGG: bli:BL00953 lysine---8-amino-7-oxononanoate aminotransferase gene gene4628 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04629 S100141_04630 S100141_04630 bioF bioF 4384575 4385714 + 8-amino-7-oxononanoate synthase Biotin biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Catalyzes the decarboxylative condensation of pimeloyl- [acyl-carrier protein] and L-alanine to produce 8-amino-7- oxononanoate (AON)%2C [acyl-carrier protein]%2C and carbon dioxide%3B Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily%3B KEGG: bli:BL00954 8-amino-7-oxononanoate synthase gene gene4629 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04630 S100141_04631 S100141_04631 bioD bioD 4385711 4386418 + Dethiobiotin synthase ATP-binding%3B Biotin biosynthesis%3B Cytoplasm%3B Ligase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Catalyzes a mechanistically unusual reaction%2C the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7%2C8-diaminopelargonic acid (DAPA) to form an ureido ring%3B Belongs to the dethiobiotin synthetase family%3B KEGG: acu:Atc_2625 dethiobiotin synthetase gene gene4630 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04631 S100141_04632 S100141_04632 bioB bioB 4386415 4387416 + Biotin synthase 2Fe-2S%3B 4Fe-4S%3B Biotin biosynthesis%3B Iron%3B Iron-sulfur%3B Metal-binding%3B S-adenosyl-L-methionine%3B Transferase%3B Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism%3B Belongs to the radical SAM superfamily. Biotin synthase family%3B KEGG: bsu:BSU30200 biotin synthase gene gene4631 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04632 S100141_04633 S100141_04633 bioI bioI 4387434 4388630 + Pimeloyl-[acyl-carrier protein] synthase Biotin biosynthesis%3B Disulfide bond%3B Heme%3B Iron%3B Metal-binding%3B Monooxygenase%3B Oxidoreductase%3B Catalyzes the C-C bond cleavage of fatty acid linked to acyl carrier protein (ACP) to generate pimelic acid for biotin biosynthesis. It has high affinity for long-chain fatty acids with the greatest affinity for myristic acid%3B Belongs to the cytochrome P450 family%3B KEGG: bli:BL00957 pimeloyl-(acyl-carrier protein) synthase gene gene4632 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04633 S100141_04634 S100141_04634 S100141_04634 4388673 4389503 - Sodium channel protein 1 brain Glycoprotein%3B Ion channel%3B Ion transport%3B Membrane%3B Phosphoprotein%3B Repeat%3B Sodium%3B Sodium channel%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Voltage-gated channel%3B Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane%2C the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. Belongs to the sodium channel (TC 1. A. 1. 10) family gene gene4633 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04634 S100141_04635 S100141_04635 S100141_04635 4389666 4390088 + HTH-type transcriptional regulator YfmP DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Repressor of the yfmOP operon. A mutation in yfmP leads to overexpression of yfmO%2C probably causing a decrease in cellular copper that is eventually responsible for a reduced copper induction of copZA%3B Contains 1 HTH merR-type DNA-binding domain gene gene4634 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04635 S100141_04636 S100141_04636 S100141_04636 4390147 4391331 + Multidrug efflux protein YfmO Cell membrane%3B Copper%3B Copper transport%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Acts to efflux copper or a copper complex. It is possible that YfmO could contribute to copper resistance%3B Belongs to the major facilitator superfamily gene gene4635 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04636 S100141_04637 S100141_04637 S100141_04637 4391374 4392930 - Heme-transporting ATPase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Ion transport%3B Membrane%3B Nucleotide-binding%3B Transport%3B Zinc%3B Zinc transport%3B Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Zinc importer (TC 3. A. 1. 15. 5) family%3B Contains 1 ABC transporter domain%3B KEGG: etr:ETAE_2461 heme exporter protein A gene gene4636 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04637 S100141_04638 S100141_04638 S100141_04638 4393068 4394198 + RNA helicase ATP-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Ribosome biogenesis%3B RNA-binding%3B A probable DEAD-box RNA helicase that plays a role in ribosomal 50S subunit assembly. May be a non-specific RNA helicase%3B Belongs to the DEAD box helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: ssu:SSU05_1739 ATP-dependent RNA helicase CshB gene gene4637 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04638 S100141_04639 S100141_04639 S100141_04639 4394242 4395264 - Putative NADP-dependent oxidoreductase YfmJ Aromatic hydrocarbons catabolism%3B Detoxification%3B NADP%3B Oxidoreductase%3B Putative quinone oxidoreductase that may contribute to the degradation of aromatic compounds%3B Belongs to the NADP-dependent oxidoreductase L4BD family gene gene4638 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04639 S100141_04640 S100141_04640 S100141_04640 4395321 4395704 - uncharacterized protein gene gene4639 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04640 S100141_04641 S100141_04641 S100141_04641 4395899 4396246 + General stress protein 17M Stress response. gene gene4640 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04641 S100141_04642 S100141_04642 S100141_04642 4396356 4397792 + Putative malate transporter YflS Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Might be a malate transporter. Belongs to the SLC13A/DASS transporter (TC 2. A. 47) family. DIT1 subfamily gene gene4641 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04642 S100141_04643 S100141_04643 S100141_04643 4397920 4398027 + hypothetical protein gene gene4642 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04643 S100141_04644 S100141_04644 S100141_04644 4398027 4398497 + hypothetical protein gene gene4643 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04644 S100141_04645 S100141_04645 S100141_04645 4398544 4399326 - Hydroxyacylglutathione hydrolase Hydrolase%3B Metal-binding%3B Zinc%3B Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family%3B KEGG: rha:RHA1_ro06806 hydroxyacylglutathione hydrolase gene gene4644 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04645 S100141_04646 S100141_04646 S100141_04646 4399429 4400226 + putative metallo-hydrolase YflN Hydrolase%3B Metal-binding%3B Zinc%3B Belongs to the metallo-beta-lactamase superfamily gene gene4645 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04646 S100141_04647 S100141_04647 S100141_04647 4400435 4402078 + putative carboxypeptidase Carboxypeptidase%3B Glycoprotein%3B Hydrolase%3B Protease%3B Secreted%3B Signal%3B Virulence%3B Extracellular metalloprotease that contributes to pathogenicity%3B Belongs to the peptidase M14 family gene gene4646 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04647 S100141_04648 S100141_04648 S100141_04648 4402207 4403304 + Nitric-oxide synthase (NAD(P)H) Heme%3B Iron%3B Metal-binding%3B NAD%3B NADP%3B Oxidoreductase%3B Catalyzes the production of nitric oxide%3B Belongs to the NOS family. Bacterial NOS oxygenase subfamily%3B KEGG: bli:BL03064 nitric-oxide synthase%2C bacterial gene gene4647 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04648 S100141_04649 S100141_04649 S100141_04649 4403392 4404030 - hypothetical protein gene gene4648 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04649 S100141_04650 S100141_04650 S100141_04650 4404027 4404311 - HTH-type transcriptional regulator KmtR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Represses expression of Rv2025c and its own expression. Acts by binding to the promoter regions%3B Contains 1 HTH arsR-type DNA-binding domain gene gene4649 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04650 S100141_04651 S100141_04651 acyP acyP 4404418 4404690 - Acylphosphatase Hydrolase%3B Belongs to the acylphosphatase family%3B Contains 1 acylphosphatase-like domain%3B KEGG: bsu:BSU07640 acylphosphatase gene gene4650 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04651 S100141_04652 S100141_04652 S100141_04652 4404802 4405452 + uncharacterized protein Contains 1 MOSC domain gene gene4651 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04652 S100141_04653 S100141_04653 S100141_04653 4405679 4405810 - uncharacterized protein gene gene4652 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04653 S100141_04654 S100141_04654 S100141_04654 4405942 4406097 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4653 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04654 S100141_04655 S100141_04655 S100141_04655 4406183 4406935 - Methionyl aminopeptidase Aminopeptidase%3B Cytoplasm%3B Hydrolase%3B Metal-binding%3B Protease%3B Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-%2C Cys%2C Gly%2C Pro%2C Ser%2C Thr%2C or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed%3B Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily%3B KEGG: ara:Arad_3299 methionyl aminopeptidase gene gene4654 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04655 S100141_04656 S100141_04656 S100141_04656 4407060 4409021 - Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase Cell membrane%3B Cell wall biogenesis/degradation%3B Manganese%3B Membrane%3B Metal-binding%3B Secreted%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate%2C a reaction that presumably uses phosphatidylglycerol (PG) as substrate%3B Belongs to the LTA synthase family%3B KEGG: bld:BLi00793 lipoteichoic acid synthase gene gene4655 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04656 S100141_04657 S100141_04657 S100141_04657 4409283 4409669 + uncharacterized protein gene gene4656 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04657 S100141_04658 S100141_04658 S100141_04658 4409731 4411143 + putative transporter YflA Cell membrane%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the sodium:alanine (SAF) symporter family gene gene4657 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04658 S100141_04659 S100141_04659 treB treB 4411332 4412744 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Kinase%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in trehalose transport. Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bsu:BSU07800 PTS system%2C trehalose-specific IIB component gene gene4658 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04659 S100141_04660 S100141_04660 treC treC 4412808 4414505 + Alpha%2Calpha-phosphotrehalase Cytoplasm%3B Glycosidase%3B Hydrolase%3B Belongs to the glycosyl hydrolase 13 family%3B KEGG: bli:BL03069 trehalose-6-phosphate hydrolase gene gene4659 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04660 S100141_04661 S100141_04661 S100141_04661 4414527 4415243 + Trehalose operon transcriptional repressor DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Repressor for the trehalose operon (treP and treA). Binds trehalose-6-phosphate%2C which probably acts as an inducer. Contains 1 HTH gntR-type DNA-binding domain gene gene4660 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04661 S100141_04662 S100141_04662 lpxA lpxA 4415350 4416042 + Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase Acyltransferase%3B Cytoplasm%3B Lipid A biosynthesis%3B Lipid biosynthesis%3B Lipid metabolism%3B Repeat%3B Transferase%3B Involved in the biosynthesis of lipid A%2C a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell%3B Belongs to the transferase hexapeptide repeat family. LpxA subfamily%3B KEGG: mvs:MVIS_3839 UDP-N-acetylglucosamine acyltransferase gene gene4661 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04662 S100141_04663 S100141_04663 S100141_04663 4416169 4417467 + Collectin-12 Calcium%3B Coiled coil%3B Collagen%3B Disulfide bond%3B Lectin%3B Membrane%3B Metal-binding%3B Receptor%3B Repeat%3B Signal-anchor%3B Transmembrane%3B Transmembrane helix%3B Scavenger receptor that displays several functions associated with host defense. Binds to carbohydrates (By similarity)%3B Contains 1 C-type lectin domain%3B Contains 2 collagen-like domains gene gene4662 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04663 S100141_04664 S100141_04664 S100141_04664 4417687 4419015 + Collagen alpha-2(I) chain Collagen%3B Extinct organism protein%3B Extracellular matrix%3B Hydroxylation%3B Pyrrolidone carboxylic acid%3B Repeat%3B Secreted%3B Type I collagen is a member of group I collagen (fibrillar forming collagen)%3B Belongs to the fibrillar collagen family%3B Contains 9 collagen-like domains gene gene4663 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04664 S100141_04665 S100141_04665 S100141_04665 4418842 4421493 - Ubiquilin-2 Acetylation%3B Amyotrophic lateral sclerosis%3B Autophagy%3B Cytoplasm%3B Cytoplasmic vesicle%3B Disease mutation%3B Membrane%3B Neurodegeneration%3B Nucleus%3B Polymorphism%3B Repeat%3B Plays an important role in the regulation of different protein degradation mechanisms and pathways including ubiquitin- proteasome system (UPS)%2C autophagy and the endoplasmic reticulum- associated protein degradation (ERAD) pathway. Mediates the proteasomal targeting of misfolded or accumulated proteins for degradation by binding (via UBA domain) to their polyubiquitin chains and by interacting (via ubiquitin-like domain) with the subunits of the proteasome (PubMed:10983987). Plays a role in the ERAD pathway via its interaction with ER-localized proteins FAF2/UBXD8 and HERPUD1 and may form a link between the polyubiquitinated ERAD substrates and the proteasome (PubMed:24215460%2C PubMed:18307982). Involved in the regulation of macroautophagy and autophagosome formatio%3B required for maturation of autophagy-related protein LC3 from the cytosolic form LC3-I to the membrane-bound form LC3-II and may assist in the maturation of autophagosomes to autolysosomes by mediating autophagosome-lysosome fusion (PubMed:19148225%2C PubMed:20529957). Negatively regulates the endocytosis of GPCR receptors: AVPR2 and ADRB2%2C by specifically reducing the rate at which receptor- arrestin complexes concentrate in clathrin-coated pits (CCPs) (PubMed:18199683)%3B Contains 4 STI1 domains%3B Contains 1 UBA domain%3B Contains 1 ubiquitin-like domain gene gene4664 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04665 S100141_04666 S100141_04666 S100141_04666 4422062 4422922 - putative transposase-like protein DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene4665 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04666 S100141_04667 S100141_04667 S100141_04667 4422892 4423224 - hypothetical protein gene gene4666 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04667 S100141_04668 S100141_04668 arnB arnB 4423337 4424428 - UDP-4-amino-4-deoxy-L-arabinose aminotransferase Aminotransferase%3B Lipopolysaccharide biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Catalyzes the synthesis of GDP-perosamine from GDP-4- keto-6-deoxy-D-mannose and L-glutamate. Can use only L-glutamate as amino donor%3B Belongs to the DegT/DnrJ/EryC1 family%3B KEGG: pam:PANA_4002 UDP-4-amino-4-deoxy-L-arabinose-oxoglutarate aminotransferase gene gene4667 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04668 S100141_04669 S100141_04669 S100141_04669 4424425 4424967 - Maltose O-acetyltransferase Acyltransferase%3B Amino-acid biosynthesis%3B Diaminopimelate biosynthesis%3B Lysine biosynthesis%3B Repeat%3B Transferase%3B Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate%3B Belongs to the transferase hexapeptide repeat family. DapH subfamily%3B KEGG: vni:VIBNI_B1816 maltose O-acetyltransferase gene gene4668 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04669 S100141_04670 S100141_04670 S100141_04670 4424985 4425959 - UDP-glucose 4-epimerase Cell wall biogenesis/degradation%3B Cytoplasm%3B Isomerase%3B Lyase%3B Multifunctional enzyme%3B NAD%3B NADP%3B Oxidoreductase%3B Ubl conjugation%3B Trifunctional enzyme involved in UDP-beta-L-rhamnose biosynthesis%2C a precursor of the primary cell wall components rhamnogalacturonan I (RG-I) and rhamnogalacturonan II (RG-II) (PubMed:14671019%2C PubMed:17190829%2C PubMed:19056285). Plays a major role in supplying UDP-rhamnose for flavonol biosynthesis (PubMed:18757557). Catalyzes the dehydration of UDP-glucose to form UDP-4-dehydro-6-deoxy-D-glucose followed by the epimerization of the C3' and C5' positions of UDP-4-dehydro-6-deoxy-D-glucose to form UDP-4-keto-beta-L-rhamnose and the reduction of UDP-4-keto- beta-L-rhamnose to yield UDP-beta-L-rhamnose (By similarity)%3B In the N-terminal sectio%3B belongs to the NAD(P)- dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily%3B In the C-terminal sectio%3B belongs to the dTDP-4- dehydrorhamnose reductase family%3B KEGG: blh:BaLi_c09080 UDP-glucose 4-epimerase gene gene4669 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04670 S100141_04671 S100141_04671 S100141_04671 4426026 4427399 - hypothetical protein gene gene4670 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04671 S100141_04672 S100141_04672 S100141_04672 4427559 4429796 - Putative teichuronic acid biosynthesis glycosyltransferase TuaG Cell wall biogenesis/degradation%3B Glycosyltransferase%3B Stress response%3B Transferase%3B Belongs to the glycosyltransferase 2 family gene gene4671 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04672 S100141_04673 S100141_04673 S100141_04673 4429991 4431073 + TPR repeat-containing protein Repeat%3B TPR repeat%3B Contains 5 TPR repeats%3B KEGG: bcz:BCZK1105 null%3B Hexosyltransferases gene gene4672 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04673 S100141_04674 S100141_04674 S100141_04674 4431112 4432305 + dTDP-3-amino-3%2C4%2C6-trideoxy-alpha-D-glucose transaminase Antibiotic biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Involved in the biosynthesis of dTDP-alpha-D-desosamine%2C a sugar found in several bacterial macrolide antibiotics. Catalyzes the reversible transfer of the amino group from L- glutamate to the C-3 position of dTDP-3-keto-4%2C6-deoxyglucose to yield dTDP-3-amino-3%2C4%2C6-trideoxyglucose%3B Belongs to the degT/dnrJ/eryC1 family%3B KEGG: csc:Csac_1802 null%3B Transaminases gene gene4673 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04674 S100141_04675 S100141_04675 wlbA wlbA 4432302 4433366 + UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase NAD%3B Oxidoreductase%3B Catalyzes the NAD(+)-dependent oxidation of scyllo- inositol to 2%2C4%2C6/3%2C5-pentahydroxycyclohexanone (scyllo-inosose)%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: plu:plu4797 UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase gene gene4674 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04675 S100141_04676 S100141_04676 wbpA wbpA 4433452 4434747 + UDP-N-acetylglucosamine 6-dehydrogenase NAD%3B Oxidoreductase%3B Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc)%2C reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA)%3B Belongs to the UDP-glucose/GDP-mannose dehydrogenase family%3B KEGG: blh:BaLi_c09140 UDP-N-acetyl-D-glucosamine dehydrogenase gene gene4675 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04676 S100141_04677 S100141_04677 S100141_04677 4434828 4435739 + uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4676 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04677 S100141_04678 S100141_04678 S100141_04678 4435736 4436128 - putative HTH-type transcriptional regulator YtcD DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH hxlR-type DNA-binding domain gene gene4677 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04678 S100141_04679 S100141_04679 S100141_04679 4436259 4436942 + Putative NAD(P)H nitroreductase YfkO Flavoprotein%3B FMN%3B NAD%3B NADP%3B Oxidoreductase%3B Belongs to the nitroreductase family%3B KEGG: oih:OB3126 null%3B Oxidoreductases gene gene4678 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04679 S100141_04680 S100141_04680 yfkN yfkN 4436984 4437664 - 2'%2C3'-cyclic-nucleotide 2'-phosphodiesterase Cell wall%3B Hydrolase%3B Metal-binding%3B Multifunctional enzyme%3B Nucleotide-binding%3B Peptidoglycan-anchor%3B Secreted%3B Signal%3B Catalyzes the release of inorganic phosphate from 2'%2C3'- cyclic nucleotides through consecutive 2'%2C3'-phosphodiesterase and 3'- (or 2') nucleotidase activities. Also possesses a 5'- nucleotidase activity. Does not catalyze the release of inorganic phosphate from 3'%2C5'-cyclic nucleotides. Probably plays a role in the cellular reprocessing of nucleotides present in the medium%2C under conditions of phosphate shortage%3B Belongs to the 5'-nucleotidase family%3B KEGG: bli:BL03110 2'%2C3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase / 5'-nucleotidase gene gene4679 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04680 S100141_04681 S100141_04681 S100141_04681 4437667 4441317 - 2'%2C3'-cyclic-nucleotide 2'-phosphodiesterase Cell wall%3B Hydrolase%3B Metal-binding%3B Multifunctional enzyme%3B Nucleotide-binding%3B Peptidoglycan-anchor%3B Secreted%3B Signal%3B Catalyzes the release of inorganic phosphate from 2'%2C3'- cyclic nucleotides through consecutive 2'%2C3'-phosphodiesterase and 3'- (or 2') nucleotidase activities. Also possesses a 5'- nucleotidase activity. Does not catalyze the release of inorganic phosphate from 3'%2C5'-cyclic nucleotides. Probably plays a role in the cellular reprocessing of nucleotides present in the medium%2C under conditions of phosphate shortage%3B Belongs to the 5'-nucleotidase family%3B KEGG: bli:BL03110 2'%2C3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase / 5'-nucleotidase gene gene4680 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04681 S100141_04682 S100141_04682 S100141_04682 4441549 4442064 + General stress protein Hydrolase%3B Protease%3B Stress response%3B Functions in the protection against aldehyde-stress%2C possibly by degrading damaged proteins%3B Belongs to the peptidase C56 family%3B Contains 1 PfpI endopeptidase domain%3B KEGG: eco:b3153 protease I%3B Glycosylases gene gene4681 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04682 S100141_04683 S100141_04683 S100141_04683 4442105 4442320 - UPF0435 protein Belongs to the UPF0435 family gene gene4682 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04683 S100141_04684 S100141_04684 S100141_04684 4442410 4443768 - Sodium/alanine symporter AgcS Amino-acid transport%3B Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably functions as a sodium/L- and D-alanine symporter for alanine uptake%3B Belongs to the sodium:alanine (SAF) symporter family gene gene4683 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04684 S100141_04685 S100141_04685 S100141_04685 4443952 4444422 + Protein-tyrosine-phosphatase Cytoplasm%3B Hydrolase%3B Protein phosphatase%3B May contribute to dephosphorylation of 'Tyr-15' of cdc2. Belongs to the low molecular weight phosphotyrosine protein phosphatase family%3B KEGG: aat:D11S_0095 protein-tyrosine phosphatase gene gene4684 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04685 S100141_04686 S100141_04686 S100141_04686 4444444 4444794 + uncharacterized protein Coiled coil%3B Signal. gene gene4685 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04686 S100141_04687 S100141_04687 S100141_04687 4444892 4445605 + Putative ribonuclease-like protein YfkH Cell membrane%3B Exonuclease%3B Hydrolase%3B Membrane%3B Nuclease%3B Transmembrane%3B Transmembrane helix. gene gene4686 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04687 S100141_04688 S100141_04688 S100141_04688 4445654 4445761 + hypothetical protein gene gene4687 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04688 S100141_04689 S100141_04689 S100141_04689 4445801 4446979 - putative MFS-type transporter YfkF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene4688 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04689 S100141_04690 S100141_04690 S100141_04690 4447080 4447460 + hypothetical protein gene gene4689 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04690 S100141_04691 S100141_04691 S100141_04691 4447565 4448620 + Ca(2+)/H(+) antiporter ChaA Antiport%3B Calcium%3B Calcium transport%3B Cell membrane%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons. Does not transport sodium or potassium%3B Belongs to the sodium/potassium/calcium exchanger family. Cation/proton exchanger (CAX) (TC 2. A. 19. 2) subfamily gene gene4690 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04691 S100141_04692 S100141_04692 S100141_04692 4448687 4449478 + uncharacterized protein Signal. gene gene4691 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04692 S100141_04693 S100141_04693 S100141_04693 4449507 4450628 - Putative protein YfkA 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B S-adenosyl-L-methionine%3B Belongs to the radical SAM superfamily gene gene4692 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04693 S100141_04694 S100141_04694 S100141_04694 4450772 4450957 + uncharacterized protein Coiled coil. gene gene4693 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04694 S100141_04695 S100141_04695 S100141_04695 4451063 4451857 + Peptidoglycan-N-acetylmuramic acid deacetylase PdaA Cell wall biogenesis/degradation%3B Hydrolase%3B Metal-binding%3B Signal%3B Sporulation%3B Catalyzes the deacetylation of N-acetylmuramic acid (MurNAc) residues in glycan strands of peptidoglycan%2C leading to the formation of muramic delta-lactam residues in spore cortex%2C after transpeptidation of deacetylated muramic acid residues. PdaA probably carries out both deacetylation and lactam ring formation and requires the product of CwlD activity on peptidoglycan as a substrate. Is required for germination. Cannot use chitin oligomer (hexa-N-acetylchitohexaose) as a substrate%3B Belongs to the polysaccharide deacetylase family%3B KEGG: bld:BLi00827 peptidoglycan-N-acetylmuramic acid deacetylase%3B In linear amides gene gene4694 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04695 S100141_04696 S100141_04696 gldA gldA 4452034 4452378 + Glycerol dehydrogenase KEGG: bli:BL03089 glycerol dehydrogenase%3B overlaps another CDS with the same product name gene gene4695 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04696 S100141_04697 S100141_04697 S100141_04697 4452375 4453136 + Glycerol dehydrogenase Glycerol metabolism%3B Manganese%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone (glycerone). Allows microorganisms to utilize glycerol as a source of carbon under anaerobic conditions. Exhibits a rather broad substrate specificity since it can also oxidize 1%2C2-propanediol and 2%2C3-butanediol and reduce dihydroxyacetone. Can not use NADP(+) as an electron acceptor for the oxidation of glycerol. Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: pmr:PMI2766 glycerol dehydrogenase%3B overlaps another CDS with the same product name gene gene4696 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04697 S100141_04698 S100141_04698 S100141_04698 4453321 4453785 - hypothetical protein gene gene4697 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04698 S100141_04699 S100141_04699 S100141_04699 4453974 4454933 - Putative metal ion transporter YfjQ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the CorA metal ion transporter (MIT) (TC 1. A. 35) family gene gene4698 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04699 S100141_04700 S100141_04700 alkA alkA 4455067 4455930 + DNA-3-methyladenine glycosylase II DNA damage%3B DNA repair%3B Hydrolase%3B Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine%2C 3-methylguanine%2C 7-methylguanine%2C O2- methylthymine%2C and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions%3B Belongs to the alkylbase DNA glycosidase AlkA family%3B KEGG: bli:BL03090 DNA-3-methyladenine glycosylase II gene gene4699 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04700 S100141_04701 S100141_04701 S100141_04701 4455933 4457339 + 23S rRNA (uracil(1939)-C(5))-methyltransferase Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family%3B Contains 1 TRAM domain%3B KEGG: bld:BLi00832 23S rRNA (uracil1939-C5)-methyltransferase gene gene4700 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04701 S100141_04702 S100141_04702 S100141_04702 4457389 4457868 + uncharacterized protein gene gene4701 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04702 S100141_04703 S100141_04703 S100141_04703 4458435 4458713 + hypothetical protein gene gene4702 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04703 S100141_04704 S100141_04704 S100141_04704 4458747 4458998 + hypothetical protein gene gene4703 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04704 S100141_04705 S100141_04705 S100141_04705 4459000 4459725 + uncharacterized protein gene gene4704 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04705 S100141_04706 S100141_04706 S100141_04706 4459755 4460330 - putative HTH-type transcriptional regulator YvkB DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH tetR-type DNA-binding domain gene gene4705 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04706 S100141_04707 S100141_04707 S100141_04707 4460438 4461634 + putative UDP-glucosyltransferase YdhE Glycosyltransferase%3B Transferase%3B Belongs to the UDP-glycosyltransferase family%3B KEGG: sma:SAV_945 dTDP-L-oleandrosyltransferase%3B Hexosyltransferases gene gene4706 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04707 S100141_04708 S100141_04708 S100141_04708 4461728 4462048 + uncharacterized protein Signal. gene gene4707 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04708 S100141_04709 S100141_04709 S100141_04709 4462153 4463355 + Putative niacin/nicotinamide transporter NaiP Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably involved in the uptake of amidated and deamidated forms of niacin. Increases the growth rate of E. coli that is unable to make niacin de nov%3B confers increased sensitivity to the toxic niacin analog 6-amino-nicotinamide to wild-type E. coli. There is probably another mechanism for niacin uptake. Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene4708 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04709 S100141_04710 S100141_04710 S100141_04710 4463849 4465225 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Kinase%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Negatively regulates SacY activity by catalyzing its phosphorylation on 'His-99'%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system may be involved in sucrose transport%3B Negatively regulates SacY%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bli:BL00914 PTS system%2C sucrose-specific IIB component gene gene4709 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04710 S100141_04711 S100141_04711 S100141_04711 4465268 4466110 + Levansucrase and sucrase synthesis operon antiterminator Activator%3B Phosphoprotein%3B Repeat%3B RNA-binding%3B Transcription%3B Transcription regulation%3B In the presence of sucrose%2C SacY is activated and prevents premature termination of transcription by binding to a RNA-antiterminator (RAT) sequence (partially overlapping with the terminator sequence) located upstream of the sacB gene. Formation of the SacY-RAT complex prevents alternative formation of the terminator%2C allowing transcription of the sacB gene. In the absence of sucrose%2C inhibition of SacY activity by SacX leads to termination of transcription%3B Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains gene gene4710 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04711 S100141_04712 S100141_04712 S100141_04712 4466144 4466650 - Carbonate dehydratase Belongs to the beta-class carbonic anhydrase family%3B KEGG: pjd:Pjdr2_2595 carbonic anhydrase gene gene4711 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04712 S100141_04713 S100141_04713 S100141_04713 4466662 4469283 - UPF0753 protein Belongs to the UPF0753 family gene gene4712 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04713 S100141_04714 S100141_04714 ndhF ndhF 4469280 4470812 - NADH:ubiquinone reductase (H(+)-translocating) Cell membrane%3B Membrane%3B NAD%3B Oxidoreductase%3B Quinone%3B Transmembrane%3B Transmembrane helix%3B Belongs to the complex I subunit 5 family%3B KEGG: bli:BL00918 NAD(P)H-quinone oxidoreductase subunit 5 gene gene4713 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04714 S100141_04715 S100141_04715 S100141_04715 4470988 4471362 - uncharacterized protein gene gene4714 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04715 S100141_04716 S100141_04716 S100141_04716 4471633 4472184 - Protein DJ-1 like protein B Chloroplast%3B Plastid%3B Repeat%3B Stress response%3B Transit peptide%3B May be involved in oxidative stress response%3B Belongs to the peptidase C56 family%3B Contains 2 PfpI endopeptidase domains gene gene4715 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04716 S100141_04717 S100141_04717 S100141_04717 4472394 4473368 + Pyruvate dehydrogenase (acetyl-transferring) Chloroplast%3B Glycolysis%3B Oxidoreductase%3B Plastid%3B Pyruvate%3B Thiamine pyrophosphate%3B Transit peptide%3B The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1)%2C dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity)%3B KEGG: bli:BL03012 pyruvate dehydrogenase E1 component alpha subunit gene gene4716 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04717 S100141_04718 S100141_04718 S100141_04718 4473390 4474424 + Pyruvate dehydrogenase (acetyl-transferring) Acetoin catabolism%3B Oxidoreductase%3B Catalyzes the 2%2C6-dichlorophenolindophenol-dependent cleavage of acetoin into acetate and acetaldehyde%3B KEGG: bli:BL03013 pyruvate dehydrogenase E1 component beta subunit gene gene4717 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04718 S100141_04719 S100141_04719 S100141_04719 4474447 4475580 + Dihydrolipoyllysine-residue succinyltransferase Acyltransferase%3B Lipoyl%3B Transferase%3B Tricarboxylic acid cycle%3B The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1)%2C dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity)%3B Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: hin:HI1661 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) gene gene4718 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04719 S100141_04720 S100141_04720 S100141_04720 4475599 4476975 + Dihydrolipoyl dehydrogenase Acetoin catabolism%3B Cytoplasm%3B Disulfide bond%3B FAD%3B Flavoprotein%3B Glycolysis%3B NAD%3B Oxidoreductase%3B Redox-active center%3B Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: ype:YPO3917 dihydrolipoamide dehydrogenase gene gene4719 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04720 S100141_04721 S100141_04721 S100141_04721 4477078 4478913 + Acetoin dehydrogenase operon transcriptional activator AcoR Activator%3B ATP-binding%3B DNA-binding%3B Nucleotide-binding%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Acts as a transcriptional activator of the acoABCL operon encoding the acetoin dehydrogenase complex%3B Contains 1 sigma-54 factor interaction domain gene gene4720 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04721 S100141_04722 S100141_04722 S100141_04722 4478910 4479236 - UPF0060 membrane protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0060 family gene gene4721 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04722 S100141_04723 S100141_04723 glvA glvA 4479423 4480772 + Maltose-6'-phosphate glucosidase Carbohydrate metabolism%3B Cobalt%3B Glycosidase%3B Hydrolase%3B Manganese%3B Metal-binding%3B NAD%3B Nickel%3B Is involved in the catabolism of alpha-glycosides accumulated via a phosphoenolpyruvate-dependent phosphotransferase system (PEP-PTS). Hydrolyzes a wide variety of 6-phospho-alpha-D- glucosides including maltose-6'-phosphate%2C isomaltose-6'- phosphate%2C maltitol-6-phosphate%2C trehalose-6-phosphate and the 6'- phosphorylated derivatives of the five linkage-isomeric alpha-D- glucosyl-D-fructoses: trehalulose-6'-phosphate%2C turanose-6'- phosphate%2C maltulose-6'-phosphate%2C leucrose-6'-phosphate%2C and palatinose-6'-phosphate. However%2C sucrose-6-phosphate is not a substrate for this enzyme%3B Belongs to the glycosyl hydrolase 4 family%3B KEGG: bli:BL03017 maltose-6'-phosphate glucosidase gene gene4722 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04723 S100141_04724 S100141_04724 S100141_04724 4480872 4481651 + HTH-type transcriptional regulator GlvR Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Positive regulator of the glv operon expression%2C which consists of GlvA%2C GlvR and GlvC%3B Contains 1 HTH rpiR-type DNA-binding domain%3B Contains 1 SIS domain gene gene4723 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04724 S100141_04725 S100141_04725 glvB glvB 4481670 4483259 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase Cell membrane%3B Kinase%3B Membrane%3B Phosphotransferase system%3B Sugar transport%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in maltose transport%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: cro:ROD_40441 PTS system%2C arbutin-like IIB component gene gene4724 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04725 S100141_04726 S100141_04726 S100141_04726 4483402 4483980 - hypothetical protein gene gene4725 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04726 S100141_04727 S100141_04727 S100141_04727 4484086 4485063 - hypothetical protein gene gene4726 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04727 S100141_04728 S100141_04728 S100141_04728 4485233 4485571 - putative HTH-type transcriptional regulator YvaP DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH hxlR-type DNA-binding domain gene gene4727 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04728 S100141_04729 S100141_04729 S100141_04729 4485800 4486243 + Putative oxidoreductase CatD Aromatic hydrocarbons catabolism%3B Cell membrane%3B Detoxification%3B Membrane%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Essential for growth and viability in the presence of catechol and probably involved in the detoxification of catechol%3B Belongs to the DoxX family gene gene4728 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04729 S100141_04730 S100141_04730 S100141_04730 4486215 4487075 + Catechol 2%2C3-dioxygenase Aromatic hydrocarbons catabolism%3B Detoxification%3B Dioxygenase%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Involved in the meta cleavage of catechol to 2- hydroxymuconic semialdehyde. Essential for growth and viability in the presence of catechol and probably involved in the detoxification of catechol%3B Belongs to the extradiol ring-cleavage dioxygenase family%3B KEGG: bli:BL03021 catechol 2%2C3-dioxygenase gene gene4729 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04730 S100141_04731 S100141_04731 xynD xynD 4487231 4488835 + Non-reducing end alpha-L-arabinofuranosidase Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Multifunctional enzyme%3B Polysaccharide degradation%3B Xylan degradation%3B Has a 1. 6-fold higher activity as an arabinosidase than as a beta-xylosidase when tested on the substrates nitrophenyl- beta-D-xylopyranoside and P-nitrophenyl-alpha-L-arabinofuranoside. Belongs to the glycosyl hydrolase 43 family%3B KEGG: tco:Theco_2848 arabinoxylan arabinofuranohydrolase gene gene4730 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04731 S100141_04732 S100141_04732 xynB xynB 4488825 4490372 + Xylan 1%2C4-beta-xylosidase Carbohydrate metabolism%3B Glycosidase%3B Hydrolase%3B Periplasm%3B Polysaccharide degradation%3B Signal%3B Alpha-L-arabinofuranosidase involved in xyloglucan degradation by mediating the cleavage of terminal non-reducing alpha-L-arabinofuranoside residues in xyloglucan branches%2C converting the 'S' units to 'X' units%3B Belongs to the glycosyl hydrolase 43 family%3B KEGG: bli:BL03023 xylan 1%2C4-beta-xylosidase gene gene4731 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04732 S100141_04733 S100141_04733 S100141_04733 4490369 4491214 - putative HTH-type transcriptional regulator YijO DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH araC/xylS-type DNA-binding domain gene gene4732 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04733 S100141_04734 S100141_04734 S100141_04734 4491265 4492668 + Putative ABC transporter peptide-binding protein YtcQ Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Probably part of a binding-protein-dependent transport system%3B Belongs to the bacterial solute-binding protein 1 family gene gene4733 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04734 S100141_04735 S100141_04735 S100141_04735 4492950 4493369 + NAD(P)H dehydrogenase (quinone) Cytoplasm%3B FAD%3B Flavoprotein%3B NAD%3B NADP%3B Oxidoreductase%3B The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis%3B Belongs to the NAD(P)H dehydrogenase (quinone) family%3B KEGG: bli:BL03025 NAD(P)H dehydrogenase (quinone) gene gene4734 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04735 S100141_04736 S100141_04736 S100141_04736 4493366 4493977 + ADP-ribose diphosphatase Hydrolase%3B Magnesium%3B Manganese%3B Metal-binding%3B Probably mediates the hydrolysis of some nucleoside diphosphate derivatives%3B Belongs to the Nudix hydrolase family%3B Contains 1 nudix hydrolase domain%3B KEGG: bcl:ABC0282 ADP-ribose pyrophosphatase gene gene4735 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04736 S100141_04737 S100141_04737 S100141_04737 4493992 4494522 + Putative metal-dependent hydrolase Cytoplasm%3B Hydrolase%3B Metal-binding%3B Zinc%3B Possible metal-dependent hydrolase%3B Belongs to the metal hydrolase YfiT family gene gene4736 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04737 S100141_04738 S100141_04738 mprF mprF 4494710 4497262 + Lysyltransferase Antibiotic resistance%3B Cell membrane%3B Lipid metabolism%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG)%2C which produces lysylphosphatidylglycerol (LPG)%2C one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects B. subtilis against its own CAMPs and against those produced by competiting microorganisms (bacteriocins). In fact%2C the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides%3B Belongs to the LPG synthase family%3B KEGG: bli:BL03028 phosphatidylglycerol lysyltransferase gene gene4737 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04738 S100141_04739 S100141_04739 S100141_04739 4497259 4497390 + hypothetical protein gene gene4738 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04739 S100141_04740 S100141_04740 S100141_04740 4497377 4498273 + Trans-2%2C3-dihydro-3-hydroxyanthranilate isomerase Isomerase%3B Belongs to the PhzF family%3B KEGG: rle:RL4013 trans-2%2C3-dihydro-3-hydroxyanthranilate isomerase gene gene4739 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04740 S100141_04741 S100141_04741 bluB bluB 4498373 4498951 + 5%2C6-dimethylbenzimidazole synthase Flavoprotein%3B FMN%3B NAD%3B NADP%3B Oxidoreductase%3B Belongs to the nitroreductase family%3B KEGG: baci:B1NLA3E_15285 5%2C6-dimethylbenzimidazole synthase gene gene4740 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04741 S100141_04742 S100141_04742 S100141_04742 4498991 4499185 - uncharacterized protein gene gene4741 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04742 S100141_04743 S100141_04743 S100141_04743 4499254 4499367 - hypothetical protein gene gene4742 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04743 S100141_04744 S100141_04744 S100141_04744 4499434 4499964 - Ribosomal-protein-alanine N-acetyltransferase KEGG: bce:BC4195 ribosomal-protein-alanine N-acetyltransferase gene gene4743 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04744 S100141_04745 S100141_04745 S100141_04745 4500231 4501130 - Epimerase family protein YfhF Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily gene gene4744 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04745 S100141_04746 S100141_04746 S100141_04746 4501199 4501990 + Regulatory protein RecX Cytoplasm%3B Modulates RecA activity%3B Belongs to the RecX family gene gene4745 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04746 S100141_04747 S100141_04747 S100141_04747 4501995 4502309 + uncharacterized protein gene gene4746 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04747 S100141_04748 S100141_04748 S100141_04748 4502340 4502510 - hypothetical protein gene gene4747 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04748 S100141_04749 S100141_04749 S100141_04749 4502537 4502686 - Small%2C acid-soluble spore protein Sporulation%3B Belongs to the SspK family gene gene4748 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04749 S100141_04750 S100141_04750 S100141_04750 4502818 4503087 + uncharacterized protein gene gene4749 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04750 S100141_04751 S100141_04751 arnC arnC 4503780 4504739 + Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase Cell membrane%3B Glycosyltransferase%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Belongs to the glycosyltransferase 2 family. GtrB subfamily%3B KEGG: gme:Gmet_0885 undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase gene gene4750 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04751 S100141_04752 S100141_04752 S100141_04752 4504708 4505109 + hypothetical protein gene gene4751 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04752 S100141_04753 S100141_04753 S100141_04753 4505106 4507691 + uncharacterized protein Cell membrane%3B Coiled coil%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene4752 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04753 S100141_04754 S100141_04754 S100141_04754 4507688 4508671 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B May act as a negative regulator for the transcription of yfhQ%2C fabL%2C sspE and yfhP gene gene4753 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04754 S100141_04755 S100141_04755 mutY mutY 4508879 4509964 + putative A/G-specific adenine glycosylase YfhQ 4Fe-4S%3B DNA damage%3B DNA repair%3B Glycosidase%3B Hydrolase%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7%2C8-dihydro-8-oxoguanine%2C 8- oxo-dGTP) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A. T to G. C transversions (By similarity). Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7%2C8-dihydro-8- oxoguanine (By similarity)%3B Belongs to the Nth/MutY family%3B Contains 1 HhH domain%3B KEGG: bli:BL03038 A/G-specific adenine glycosylase%3B Hydrolyzing N-glycosyl compounds gene gene4754 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04755 S100141_04756 S100141_04756 S100141_04756 4509990 4510214 - uncharacterized protein gene gene4755 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04756 S100141_04757 S100141_04757 phbB phbB 4510297 4511049 + Acetoacetyl-CoA reductase Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B NADP%3B Oxidoreductase%3B Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). It confers resistance to triclosan%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: jag:GJA_3696 acetoacetyl-CoA reductase gene gene4756 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04757 S100141_04758 S100141_04758 S100141_04758 4511118 4511282 + Small%2C acid-soluble spore protein gamma-type Repeat%3B Sporulation%3B SASP are proteins degraded in the first minutes of spore germination and provide amino acids for both new protein synthesis and metabolism. These proteins may be involved in dormant spore's high resistance to UV light. Belongs to the gamma-type SASP family gene gene4757 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04758 S100141_04759 S100141_04759 S100141_04759 4511450 4511695 + uncharacterized protein Coiled coil. gene gene4758 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04759 S100141_04760 S100141_04760 S100141_04760 4511859 4512389 + UPF0374 protein Belongs to the UPF0374 family gene gene4759 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04760 S100141_04761 S100141_04761 S100141_04761 4512465 4514207 + Putative multidrug export ATP-binding/permease protein YgaD ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B May be involved in multidrug export. Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain%3B KEGG: bsu:BSU08690 ATP-binding cassette%2C subfamily B%2C bacterial MsbA%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene4760 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04761 S100141_04762 S100141_04762 S100141_04762 4514338 4515318 + Oligopeptide transport ATP-binding protein OppD ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Peptide transport%3B Protein transport%3B Transport%3B Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene4761 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04762 S100141_04763 S100141_04763 S100141_04763 4515315 4516271 + Macrolide export ATP-binding/permease protein MacB Antibiotic resistance%3B ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD)%2C which form a pore in the inner membrane%2C and an ATP-binding domain (NBD)%2C which is responsible for energy generation. Confers resistance against macrolides%3B Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3. A. 1. 122) family%3B Contains 1 ABC transporter domain gene gene4762 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04763 S100141_04764 S100141_04764 S100141_04764 4516268 4517866 + Periplasmic dipeptide transport protein Chemotaxis%3B Disulfide bond%3B Peptide transport%3B Periplasm%3B Protein transport%3B Signal%3B Transport%3B Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis. Belongs to the bacterial solute-binding protein 5 family gene gene4763 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04764 S100141_04765 S100141_04765 S100141_04765 4517880 4518881 + Oligopeptide transport system permease protein AppB Cell membrane%3B Competence%3B Membrane%3B Peptide transport%3B Protein transport%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence%2C though%2C unlike OPP%2C is incapable of transporting tripeptides. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene4764 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04765 S100141_04766 S100141_04766 S100141_04766 4518894 4519784 + putative D%2CD-dipeptide transport system permease protein DdpC Cell inner membrane%3B Cell membrane%3B Membrane%3B Peptide transport%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex DdpABCDF%2C which is probably involved in D%2CD-dipeptide transport. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene4765 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04766 S100141_04767 S100141_04767 S100141_04767 4519814 4520884 - UPF0421 protein YgaE Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0421 family gene gene4766 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04767 S100141_04768 S100141_04768 S100141_04768 4521137 4522435 - Glutamate-1-semialdehyde 2%2C1-aminomutase Cytoplasm%3B Isomerase%3B Porphyrin biosynthesis%3B Pyridoxal phosphate%3B Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily%3B KEGG: bli:BL03060 glutamate-1-semialdehyde 2%2C1-aminomutase gene gene4767 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04768 S100141_04769 S100141_04769 S100141_04769 4522599 4523072 + Peroxiredoxin Oxidoreductase%3B Peroxidase%3B Redox-active center%3B Belongs to the AhpC/TSA family%3B Contains 1 thioredoxin domain%3B KEGG: cbu:CBU_0963 peroxiredoxin Q/BCP gene gene4768 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04769 S100141_04770 S100141_04770 S100141_04770 4523285 4523722 + Peroxide operon regulator Cytoplasm%3B Disulfide bond%3B DNA-binding%3B Manganese%3B Metal-binding%3B Oxidation%3B Repressor%3B Transcription%3B Transcription regulation%3B Zinc%3B Hydrogen and organic peroxide sensor. Represses the expression of a regulon of peroxide-inducible genes such as katA%2C ahpC%2C ahpF%2C the heme biosynthesis operon (hemAXCDBL)%2C fur%2C perR%2C zosA and mrgA. Belongs to the Fur family gene gene4769 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04770 S100141_04771 S100141_04771 S100141_04771 4523771 4524118 - UPF0295 protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0295 family gene gene4770 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04771 S100141_04772 S100141_04772 S100141_04772 4524336 4525220 + uncharacterized protein gene gene4771 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04772 S100141_04773 S100141_04773 S100141_04773 4525508 4527057 + 16S ribosomal RNA rRNA gene4772 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04773 S100141_04774 S100141_04774 S100141_04774 4527232 4530162 + 23S ribosomal RNA rRNA gene4773 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04774 S100141_04775 S100141_04775 S100141_04775 4530333 4530448 + 5S ribosomal RNA rRNA gene4774 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04775 S100141_04776 S100141_04776 S100141_04776 4530458 4530532 + tRNA-Asn tRNA gene4775 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04776 S100141_04777 S100141_04777 S100141_04777 4530539 4530630 + tRNA-Ser tRNA gene4776 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04777 S100141_04778 S100141_04778 S100141_04778 4530645 4530719 + tRNA-Glu tRNA gene4777 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04778 S100141_04779 S100141_04779 S100141_04779 4530837 4530912 + tRNA-Val tRNA gene4778 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04779 S100141_04780 S100141_04780 S100141_04780 4530934 4531010 + tRNA-Met tRNA gene4779 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04780 S100141_04781 S100141_04781 S100141_04781 4531025 4531101 + tRNA-Asp tRNA gene4780 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04781 S100141_04782 S100141_04782 S100141_04782 4531112 4531187 + tRNA-Phe tRNA gene4781 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04782 S100141_04783 S100141_04783 S100141_04783 4531191 4531263 + tRNA-Thr tRNA gene4782 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04783 S100141_04784 S100141_04784 S100141_04784 4531271 4531355 + tRNA-Tyr tRNA gene4783 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04784 S100141_04785 S100141_04785 S100141_04785 4531363 4531436 + tRNA-Trp tRNA gene4784 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04785 S100141_04786 S100141_04786 S100141_04786 4531457 4531529 + tRNA-His tRNA gene4785 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04786 S100141_04787 S100141_04787 S100141_04787 4531538 4531609 + tRNA-Gln tRNA gene4786 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04787 S100141_04788 S100141_04788 S100141_04788 4531663 4531737 + tRNA-Gly tRNA gene4787 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04788 S100141_04789 S100141_04789 S100141_04789 4531751 4531821 + tRNA-Cys tRNA gene4788 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04789 S100141_04790 S100141_04790 S100141_04790 4531832 4531920 + tRNA-Leu tRNA gene4789 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04790 S100141_04791 S100141_04791 S100141_04791 4532106 4533065 + Tyrosine recombinase XerC Cell cycle%3B Cell division%3B Chromosome partition%3B Cytoplasm%3B DNA integration%3B DNA recombination%3B DNA-binding%3B Site-specific tyrosine recombinase%2C which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids%3B Belongs to the 'phage' integrase family. XerC subfamily gene gene4790 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04791 S100141_04792 S100141_04792 S100141_04792 4533325 4534254 + hypothetical protein gene gene4791 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04792 S100141_04793 S100141_04793 S100141_04793 4534271 4534645 + hypothetical protein gene gene4792 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04793 S100141_04794 S100141_04794 S100141_04794 4534840 4535187 + hypothetical protein gene gene4793 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04794 S100141_04795 S100141_04795 S100141_04795 4535165 4535353 + hypothetical protein gene gene4794 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04795 S100141_04796 S100141_04796 S100141_04796 4535353 4535676 + hypothetical protein gene gene4795 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04796 S100141_04797 S100141_04797 S100141_04797 4535851 4536186 + hypothetical protein gene gene4796 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04797 S100141_04798 S100141_04798 S100141_04798 4536183 4536428 + hypothetical protein gene gene4797 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04798 S100141_04799 S100141_04799 S100141_04799 4536428 4536601 + hypothetical protein gene gene4798 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04799 S100141_04800 S100141_04800 S100141_04800 4536602 4536928 + hypothetical protein gene gene4799 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04800 S100141_04801 S100141_04801 S100141_04801 4536928 4537296 + hypothetical protein gene gene4800 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04801 S100141_04802 S100141_04802 S100141_04802 4537280 4537663 + hypothetical protein gene gene4801 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04802 S100141_04803 S100141_04803 S100141_04803 4537680 4538075 + hypothetical protein gene gene4802 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04803 S100141_04804 S100141_04804 S100141_04804 4538068 4538274 + hypothetical protein gene gene4803 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04804 S100141_04805 S100141_04805 S100141_04805 4538271 4538417 + hypothetical protein gene gene4804 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04805 S100141_04806 S100141_04806 S100141_04806 4538436 4539230 + hypothetical protein gene gene4805 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04806 S100141_04807 S100141_04807 S100141_04807 4539200 4539700 + hypothetical protein gene gene4806 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04807 S100141_04808 S100141_04808 S100141_04808 4539700 4539903 + hypothetical protein gene gene4807 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04808 S100141_04809 S100141_04809 S100141_04809 4539900 4540988 + DNA helicase KEGG: bao:BAMF_0894 replicative DNA helicase gene gene4808 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04809 S100141_04810 S100141_04810 S100141_04810 4541092 4541247 + DNA helicase KEGG: bao:BAMF_0894 replicative DNA helicase gene gene4809 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04810 S100141_04811 S100141_04811 S100141_04811 4541269 4541514 + hypothetical protein gene gene4810 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04811 S100141_04812 S100141_04812 S100141_04812 4541886 4542440 + hypothetical protein gene gene4811 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04812 S100141_04813 S100141_04813 S100141_04813 4542884 4543048 + hypothetical protein gene gene4812 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04813 S100141_04814 S100141_04814 S100141_04814 4543983 4544168 + hypothetical protein gene gene4813 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04814 S100141_04815 S100141_04815 S100141_04815 33 1421 - hypothetical protein gene gene4913 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04815 S100141_04816 S100141_04816 S100141_04816 1447 1884 - hypothetical protein gene gene4914 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04816 S100141_04817 S100141_04817 S100141_04817 1978 2463 - hypothetical protein gene gene4915 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04817 S100141_04818 S100141_04818 S100141_04818 2560 3288 - hypothetical protein gene gene4916 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04818 S100141_04819 S100141_04819 S100141_04819 3278 3511 - hypothetical protein gene gene4917 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04819 S100141_04820 S100141_04820 S100141_04820 3517 3744 - hypothetical protein gene gene4918 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04820 S100141_04821 S100141_04821 S100141_04821 3753 5117 - DNA primase DNA replication%3B DNA-binding%3B DNA-directed RNA polymerase%3B Magnesium%3B Metal-binding%3B Nucleotidyltransferase%3B Primosome%3B Transcription%3B Transferase%3B Zinc%3B Zinc-finger%3B RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication%3B Belongs to the DnaG primase family%3B Contains 1 Toprim domain%3B KEGG: aps:CFPG_441 DNA primase%3B Nucleotidyltransferases gene gene4919 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04821 S100141_04822 S100141_04822 S100141_04822 5173 6135 - Protein ORF73 gene gene4920 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04822 S100141_04823 S100141_04823 S100141_04823 6240 8228 - DNA helicase ATP-binding%3B DNA damage%3B DNA repair%3B DNA replication%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Has both ATPase and helicase activities. Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present. Involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair (By similarity)%3B Belongs to the helicase family. UvrD subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: psim:KR76_09305 DNA helicase II / ATP-dependent DNA helicase PcrA gene gene4921 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04823 S100141_04824 S100141_04824 S100141_04824 8448 8648 - hypothetical protein gene gene4922 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04824 S100141_04825 S100141_04825 S100141_04825 8692 10389 - hypothetical protein gene gene4923 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04825 S100141_04826 S100141_04826 S100141_04826 10623 11204 - hypothetical protein gene gene4924 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04826 S100141_04827 S100141_04827 S100141_04827 11250 11627 - hypothetical protein gene gene4925 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04827 S100141_04828 S100141_04828 S100141_04828 11950 12186 - hypothetical protein gene gene4926 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04828 S100141_04829 S100141_04829 S100141_04829 12519 12734 - hypothetical protein gene gene4927 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04829 S100141_04830 S100141_04830 S100141_04830 12748 13023 - hypothetical protein gene gene4928 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04830 S100141_04831 S100141_04831 S100141_04831 13084 13464 - hypothetical protein gene gene4929 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04831 S100141_04832 S100141_04832 S100141_04832 13533 13928 - hypothetical protein gene gene4930 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04832 S100141_04833 S100141_04833 S100141_04833 13929 15602 - Vesicle-fusing ATPase ATP-binding%3B Chloroplast%3B Nucleotide-binding%3B Plastid%3B Belongs to the AAA ATPase family. Highly divergent%3B KEGG: pca:Pcar_0681 vesicle-fusing ATPase gene gene4931 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04833 S100141_04834 S100141_04834 S100141_04834 15663 15935 - hypothetical protein gene gene4932 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04834 S100141_04835 S100141_04835 S100141_04835 15956 16123 - hypothetical protein gene gene4933 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04835 S100141_04836 S100141_04836 S100141_04836 16329 17081 - hypothetical protein gene gene4934 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04836 S100141_04837 S100141_04837 S100141_04837 17128 17538 - hypothetical protein gene gene4935 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04837 S100141_04838 S100141_04838 S100141_04838 17535 17804 - hypothetical protein gene gene4936 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04838 S100141_04839 S100141_04839 S100141_04839 17838 18071 - hypothetical protein gene gene4937 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04839 S100141_04840 S100141_04840 S100141_04840 18095 18982 - hypothetical protein gene gene4938 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04840 S100141_04841 S100141_04841 S100141_04841 19010 19828 - hypothetical protein gene gene4939 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04841 S100141_04842 S100141_04842 S100141_04842 19825 19974 - hypothetical protein gene gene4940 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04842 S100141_04843 S100141_04843 S100141_04843 20121 20315 - hypothetical protein gene gene4941 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04843 S100141_04844 S100141_04844 S100141_04844 20333 21010 - hypothetical protein gene gene4942 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04844 S100141_04845 S100141_04845 S100141_04845 21058 21447 - hypothetical protein gene gene4943 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04845 S100141_04846 S100141_04846 S100141_04846 21462 22139 - hypothetical protein gene gene4944 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04846 S100141_04847 S100141_04847 S100141_04847 22136 22594 - hypothetical protein gene gene4945 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04847 S100141_04848 S100141_04848 S100141_04848 22591 22920 - hypothetical protein gene gene4946 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04848 S100141_04849 S100141_04849 S100141_04849 22913 23740 - hypothetical protein gene gene4947 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04849 S100141_04850 S100141_04850 S100141_04850 23761 24306 - hypothetical protein gene gene4948 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04850 S100141_04851 S100141_04851 S100141_04851 24352 24822 - hypothetical protein gene gene4949 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04851 S100141_04852 S100141_04852 S100141_04852 24850 25080 - hypothetical protein gene gene4950 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04852 S100141_04853 S100141_04853 S100141_04853 25098 25619 - hypothetical protein gene gene4951 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04853 S100141_04854 S100141_04854 S100141_04854 25918 26190 - hypothetical protein gene gene4952 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04854 S100141_04855 S100141_04855 S100141_04855 26194 26817 - hypothetical protein gene gene4953 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04855 S100141_04856 S100141_04856 S100141_04856 26851 28026 - Protein RecA%2C plasmid ATP-binding%3B Cytoplasm%3B DNA damage%3B DNA recombination%3B DNA repair%3B DNA-binding%3B Nucleotide-binding%3B Plasmid%3B SOS response%3B It interacts with LexA causing its activation and leading to its autocatalytic cleavage. Belongs to the RecA family gene gene4954 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04856 S100141_04857 S100141_04857 S100141_04857 28007 28390 - hypothetical protein gene gene4955 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04857 S100141_04858 S100141_04858 S100141_04858 28448 29155 - hypothetical protein gene gene4956 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04858 S100141_04859 S100141_04859 S100141_04859 29219 29404 - hypothetical protein gene gene4957 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04859 S100141_04860 S100141_04860 S100141_04860 29401 29760 - hypothetical protein gene gene4958 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04860 S100141_04861 S100141_04861 S100141_04861 29747 30025 - hypothetical protein gene gene4959 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04861 S100141_04862 S100141_04862 S100141_04862 30373 30732 - hypothetical protein gene gene4960 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04862 S100141_04863 S100141_04863 S100141_04863 30841 32031 - Exodeoxyribonuclease V KEGG: bja:blr7041 exodeoxyribonuclease V gene gene4961 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04863 S100141_04864 S100141_04864 S100141_04864 32069 32485 - hypothetical protein gene gene4962 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04864 S100141_04865 S100141_04865 S100141_04865 32556 32765 - hypothetical protein gene gene4963 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04865 S100141_04866 S100141_04866 S100141_04866 32831 33055 - hypothetical protein gene gene4964 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04866 S100141_04867 S100141_04867 S100141_04867 33055 33261 - hypothetical protein gene gene4965 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04867 S100141_04868 S100141_04868 S100141_04868 33258 33446 - hypothetical protein gene gene4966 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04868 S100141_04869 S100141_04869 S100141_04869 33443 33637 - hypothetical protein gene gene4967 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04869 S100141_04870 S100141_04870 S100141_04870 33758 33949 - hypothetical protein gene gene4968 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04870 S100141_04871 S100141_04871 S100141_04871 34049 34258 - hypothetical protein gene gene4969 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04871 S100141_04872 S100141_04872 S100141_04872 34268 34738 - SPBc2 prophage-derived uncharacterized protein YopX gene gene4970 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04872 S100141_04873 S100141_04873 S100141_04873 34735 34953 - hypothetical protein gene gene4971 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04873 S100141_04874 S100141_04874 S100141_04874 34950 35072 - hypothetical protein gene gene4972 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04874 S100141_04875 S100141_04875 S100141_04875 35039 35215 - hypothetical protein gene gene4973 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04875 S100141_04876 S100141_04876 S100141_04876 35212 35466 - hypothetical protein gene gene4974 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04876 S100141_04877 S100141_04877 S100141_04877 35547 35738 - hypothetical protein gene gene4975 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04877 S100141_04878 S100141_04878 S100141_04878 35735 36130 - hypothetical protein gene gene4976 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04878 S100141_04879 S100141_04879 S100141_04879 36292 37047 - hypothetical protein gene gene4977 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04879 S100141_04880 S100141_04880 S100141_04880 37134 37265 - hypothetical protein gene gene4978 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04880 S100141_04881 S100141_04881 S100141_04881 37299 37529 - hypothetical protein gene gene4979 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04881 S100141_04882 S100141_04882 S100141_04882 37533 37814 - hypothetical protein gene gene4980 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04882 S100141_04883 S100141_04883 S100141_04883 37981 38520 - hypothetical protein gene gene4981 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04883 S100141_04884 S100141_04884 S100141_04884 38534 39055 - hypothetical protein gene gene4982 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04884 S100141_04885 S100141_04885 S100141_04885 39079 39300 - hypothetical protein gene gene4983 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04885 S100141_04886 S100141_04886 S100141_04886 39349 39546 - hypothetical protein gene gene4984 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04886 S100141_04887 S100141_04887 S100141_04887 39533 39832 - hypothetical protein gene gene4985 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04887 S100141_04888 S100141_04888 S100141_04888 39887 39988 - hypothetical protein gene gene4986 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04888 S100141_04889 S100141_04889 S100141_04889 39985 40803 - hypothetical protein gene gene4987 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04889 S100141_04890 S100141_04890 S100141_04890 40852 41148 - hypothetical protein gene gene4988 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04890 S100141_04891 S100141_04891 S100141_04891 41155 41532 - hypothetical protein gene gene4989 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04891 S100141_04892 S100141_04892 S100141_04892 41613 42008 - hypothetical protein gene gene4990 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04892 S100141_04893 S100141_04893 S100141_04893 42011 42229 - hypothetical protein gene gene4991 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04893 S100141_04894 S100141_04894 S100141_04894 42265 42468 - hypothetical protein gene gene4992 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04894 S100141_04895 S100141_04895 S100141_04895 42534 42689 - hypothetical protein gene gene4993 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04895 S100141_04896 S100141_04896 mot1 mot1 42764 44626 - RNA polymerase-associated protein RapA Activator%3B ATP-binding%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Transcription%3B Transcription regulation%3B Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP%2C when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair%3B Belongs to the SNF2/RAD54 helicase family. RapA subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: ago:AGOS_AEL256C TATA-binding protein-associated factor%3B Acting on ATP%3B involved in cellular and subcellular movement gene gene4994 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04896 S100141_04897 S100141_04897 S100141_04897 45181 46164 - hypothetical protein gene gene4995 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04897 S100141_04898 S100141_04898 S100141_04898 46186 46323 - hypothetical protein gene gene4996 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04898 S100141_04899 S100141_04899 S100141_04899 46320 46574 - hypothetical protein gene gene4997 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04899 S100141_04900 S100141_04900 S100141_04900 46990 47202 - hypothetical protein gene gene4998 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04900 S100141_04901 S100141_04901 S100141_04901 47205 47543 - hypothetical protein gene gene4999 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04901 S100141_04902 S100141_04902 S100141_04902 47560 48072 - Ribonuclease H KEGG: kci:CKCE_0449 ribonuclease HI gene gene5000 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04902 S100141_04903 S100141_04903 S100141_04903 48509 49219 + hypothetical protein gene gene5001 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04903 S100141_04904 S100141_04904 S100141_04904 49494 49670 + hypothetical protein gene gene5002 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04904 S100141_04905 S100141_04905 S100141_04905 49672 50016 + hypothetical protein gene gene5003 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04905 S100141_04906 S100141_04906 S100141_04906 50391 51125 + hypothetical protein gene gene5004 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04906 S100141_04907 S100141_04907 S100141_04907 51157 51381 - hypothetical protein gene gene5005 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04907 S100141_04908 S100141_04908 S100141_04908 51632 51958 - hypothetical protein gene gene5006 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04908 S100141_04909 S100141_04909 S100141_04909 52150 52560 - hypothetical protein gene gene5007 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04909 S100141_04910 S100141_04910 S100141_04910 53357 57136 - hypothetical protein gene gene5008 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04910 S100141_04911 S100141_04911 S100141_04911 57283 57579 - hypothetical protein gene gene5009 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04911 S100141_04912 S100141_04912 S100141_04912 57996 58172 - hypothetical protein gene gene5010 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04912 S100141_04913 S100141_04913 S100141_04913 58176 58370 - hypothetical protein gene gene5011 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04913 S100141_04914 S100141_04914 S100141_04914 58882 59520 - hypothetical protein gene gene5012 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04914 S100141_04915 S100141_04915 S100141_04915 59888 60064 + hypothetical protein gene gene5013 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04915 S100141_04916 S100141_04916 S100141_04916 60127 60594 + hypothetical protein gene gene5014 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04916 S100141_04917 S100141_04917 S100141_04917 60615 60920 + hypothetical protein gene gene5015 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04917 S100141_04918 S100141_04918 S100141_04918 60952 61338 + hypothetical protein gene gene5016 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04918 S100141_04919 S100141_04919 S100141_04919 61351 62013 + hypothetical protein gene gene5017 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04919 S100141_04920 S100141_04920 S100141_04920 62285 62359 + tRNA-Asn tRNA gene5018 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04920 S100141_04921 S100141_04921 S100141_04921 62361 62436 + tRNA-Met tRNA gene5019 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04921 S100141_04922 S100141_04922 S100141_04922 62730 63893 + hypothetical protein gene gene5020 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04922 S100141_04923 S100141_04923 S100141_04923 63893 64081 + hypothetical protein gene gene5021 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04923 S100141_04924 S100141_04924 S100141_04924 64239 64991 + hypothetical protein gene gene5022 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04924 S100141_04925 S100141_04925 S100141_04925 64997 65458 + hypothetical protein gene gene5023 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04925 S100141_04926 S100141_04926 S100141_04926 65472 65915 + hypothetical protein gene gene5024 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04926 S100141_04927 S100141_04927 S100141_04927 65932 66717 + hypothetical protein gene gene5025 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04927 S100141_04928 S100141_04928 S100141_04928 66704 67075 + hypothetical protein gene gene5026 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04928 S100141_04929 S100141_04929 S100141_04929 67090 67512 + hypothetical protein gene gene5027 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04929 S100141_04930 S100141_04930 S100141_04930 67525 67812 + hypothetical protein gene gene5028 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04930 S100141_04931 S100141_04931 S100141_04931 67831 69618 + DNA helicase KEGG: btn:BTF1_30797 replicative DNA helicase gene gene5029 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04931 S100141_04932 S100141_04932 S100141_04932 69791 71071 + hypothetical protein gene gene5030 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04932 S100141_04933 S100141_04933 S100141_04933 71165 73276 + hypothetical protein gene gene5031 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04933 S100141_04934 S100141_04934 S100141_04934 73278 74612 + hypothetical protein gene gene5032 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04934 S100141_04935 S100141_04935 S100141_04935 74625 75848 + hypothetical protein gene gene5033 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04935 S100141_04936 S100141_04936 S100141_04936 75867 76949 + hypothetical protein gene gene5034 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04936 S100141_04937 S100141_04937 S100141_04937 77027 77608 + hypothetical protein gene gene5035 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04937 S100141_04938 S100141_04938 S100141_04938 77627 79723 + hypothetical protein gene gene5036 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04938 S100141_04939 S100141_04939 S100141_04939 79730 81844 + hypothetical protein gene gene5037 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04939 S100141_04940 S100141_04940 S100141_04940 81863 83674 + hypothetical protein gene gene5038 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04940 S100141_04941 S100141_04941 S100141_04941 83689 84216 + hypothetical protein gene gene5039 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04941 S100141_04942 S100141_04942 S100141_04942 84229 84564 + hypothetical protein gene gene5040 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04942 S100141_04943 S100141_04943 S100141_04943 84571 85527 + hypothetical protein gene gene5041 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04943 S100141_04944 S100141_04944 S100141_04944 85554 86675 + hypothetical protein gene gene5042 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04944 S100141_04945 S100141_04945 S100141_04945 86675 87154 + hypothetical protein gene gene5043 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04945 S100141_04946 S100141_04946 S100141_04946 87114 88181 + hypothetical protein gene gene5044 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04946 S100141_04947 S100141_04947 S100141_04947 88196 88903 + hypothetical protein gene gene5045 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04947 S100141_04948 S100141_04948 S100141_04948 88921 91845 + hypothetical protein gene gene5046 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04948 S100141_04949 S100141_04949 S100141_04949 91914 92666 + hypothetical protein gene gene5047 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04949 S100141_04950 S100141_04950 S100141_04950 92726 93247 + hypothetical protein gene gene5048 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04950 S100141_04951 S100141_04951 S100141_04951 93244 94131 + hypothetical protein gene gene5049 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04951 S100141_04952 S100141_04952 S100141_04952 94203 94742 + hypothetical protein gene gene5050 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04952 S100141_04953 S100141_04953 S100141_04953 94786 95547 + hypothetical protein gene gene5051 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04953 S100141_04954 S100141_04954 S100141_04954 95562 101504 + hypothetical protein gene gene5052 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04954 S100141_04955 S100141_04955 S100141_04955 101517 108383 + hypothetical protein gene gene5053 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04955 S100141_04956 S100141_04956 S100141_04956 108401 114874 + putative endopeptidase YddH Hydrolase%3B Protease%3B Signal%3B Thiol protease%3B Belongs to the peptidase C40 family gene gene5054 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04956 S100141_04957 S100141_04957 S100141_04957 114885 115349 + hypothetical protein gene gene5055 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04957 S100141_04958 S100141_04958 S100141_04958 115318 115707 + hypothetical protein gene gene5056 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04958 S100141_04959 S100141_04959 S100141_04959 115694 116095 + hypothetical protein gene gene5057 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04959 S100141_04960 S100141_04960 S100141_04960 116108 116977 + hypothetical protein gene gene5058 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04960 S100141_04961 S100141_04961 S100141_04961 117048 117569 + hypothetical protein gene gene5059 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04961 S100141_04962 S100141_04962 S100141_04962 117577 117909 + hypothetical protein gene gene5060 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04962 S100141_04963 S100141_04963 S100141_04963 117922 119040 + hypothetical protein gene gene5061 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04963 S100141_04964 S100141_04964 S100141_04964 119082 120533 + hypothetical protein gene gene5062 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04964 S100141_04965 S100141_04965 S100141_04965 120549 122156 + X-linked retinitis pigmentosa GTPase regulator Alternative splicing%3B Cell projection%3B Ciliopathy%3B Cilium%3B Cilium biogenesis/degradation%3B Cone-rod dystrophy%3B Cytoplasm%3B Cytoskeleton%3B Deafness%3B Disease mutation%3B Golgi apparatus%3B Guanine-nucleotide releasing factor%3B Lipoprotein%3B Methylation%3B Polymorphism%3B Prenylation%3B Repeat%3B Retinitis pigmentosa%3B Sensory transduction%3B Vision%3B Could be a guanine-nucleotide releasing factor. Plays a role in ciliogenesis. Probably regulates cilia formation by regulating actin stress filaments and cell contractility. Plays an important role in photoreceptor integrity. May play a critical role in spermatogenesis and in intraflagellar transport processes (By similarity). May be involved in microtubule organization and regulation of transport in primary cilia%3B Contains 6 RCC1 repeats gene gene5063 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04965 S100141_04966 S100141_04966 S100141_04966 122172 122774 + hypothetical protein gene gene5064 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04966 S100141_04967 S100141_04967 S100141_04967 122794 123246 + hypothetical protein gene gene5065 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04967 S100141_04968 S100141_04968 S100141_04968 123338 123964 + hypothetical protein gene gene5066 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04968 S100141_04969 S100141_04969 S100141_04969 124060 125517 + hypothetical protein gene gene5067 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04969 S100141_04970 S100141_04970 S100141_04970 125533 132744 + Beta-glucosidase KEGG: psu:Psesu_2923 beta-glucosidase gene gene5068 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04970 S100141_04971 S100141_04971 S100141_04971 132787 139662 + hypothetical protein gene gene5069 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04971 S100141_04972 S100141_04972 S100141_04972 139715 140773 + hypothetical protein gene gene5070 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04972 S100141_04973 S100141_04973 S100141_04973 140822 143311 + hypothetical protein gene gene5071 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04973 S100141_04974 S100141_04974 S100141_04974 143318 147970 + hypothetical protein gene gene5072 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04974 S100141_04975 S100141_04975 S100141_04975 147986 150100 + hypothetical protein gene gene5073 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04975 S100141_04976 S100141_04976 S100141_04976 150109 150915 + hypothetical protein gene gene5074 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04976 S100141_04977 S100141_04977 S100141_04977 150896 152146 + hypothetical protein gene gene5075 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04977 S100141_04978 S100141_04978 S100141_04978 152165 152569 + hypothetical protein gene gene5076 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04978 S100141_04979 S100141_04979 S100141_04979 152744 153934 + hypothetical protein gene gene5077 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04979 S100141_04980 S100141_04980 S100141_04980 153946 154629 + hypothetical protein gene gene5078 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04980 S100141_04981 S100141_04981 S100141_04981 154592 155710 + hypothetical protein gene gene5079 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04981 S100141_04982 S100141_04982 S100141_04982 155913 157001 + DNA helicase KEGG: dap:Dacet_2772 replicative DNA helicase gene gene5080 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04982 S100141_04983 S100141_04983 S100141_04983 157023 157319 + hypothetical protein gene gene5081 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04983 S100141_04984 S100141_04984 S100141_04984 157331 157846 + hypothetical protein gene gene5082 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04984 S100141_04985 S100141_04985 S100141_04985 157848 158861 + hypothetical protein gene gene5083 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04985 S100141_04986 S100141_04986 S100141_04986 158907 159344 + hypothetical protein gene gene5084 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04986 S100141_04987 S100141_04987 S100141_04987 159357 159713 + hypothetical protein gene gene5085 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04987 S100141_04988 S100141_04988 S100141_04988 159700 159912 + hypothetical protein gene gene5086 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04988 S100141_04989 S100141_04989 S100141_04989 159912 160124 + hypothetical protein gene gene5087 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04989 S100141_04990 S100141_04990 S100141_04990 160127 160666 + hypothetical protein gene gene5088 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04990 S100141_04991 S100141_04991 S100141_04991 160644 160895 + hypothetical protein gene gene5089 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04991 S100141_04992 S100141_04992 S100141_04992 161036 163138 + Ribonucleoside-diphosphate reductase Allosteric enzyme%3B ATP-binding%3B Disulfide bond%3B DNA replication%3B Nucleotide-binding%3B Oxidoreductase%3B Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase large chain family%3B KEGG: bcl:ABC3108 ribonucleoside-diphosphate reductase alpha chain gene gene5090 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04992 S100141_04993 S100141_04993 S100141_04993 163182 163427 + hypothetical protein gene gene5091 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04993 S100141_04994 S100141_04994 S100141_04994 163443 164417 + Ribonucleoside-diphosphate reductase DNA replication%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase small chain family%3B KEGG: bsu:BSU17390 ribonucleoside-diphosphate reductase beta chain gene gene5092 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04994 S100141_04995 S100141_04995 S100141_04995 164431 165048 + uncharacterized protein gene gene5093 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04995 S100141_04996 S100141_04996 S100141_04996 165129 165320 + hypothetical protein gene gene5094 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04996 S100141_04997 S100141_04997 S100141_04997 165335 165691 + hypothetical protein gene gene5095 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04997 S100141_04998 S100141_04998 S100141_04998 165693 166427 + hypothetical protein gene gene5096 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04998 S100141_04999 S100141_04999 S100141_04999 166384 166854 + dCMP deaminase Allosteric enzyme%3B Hydrolase%3B Metal-binding%3B Nucleotide biosynthesis%3B Zinc%3B Supplies the nucleotide substrate for thymidylate synthetase. Belongs to the cytidine and deoxycytidylate deaminase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: mcl:MCCL_1239 dCMP deaminase gene gene5097 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_04999 S100141_05000 S100141_05000 S100141_05000 166844 167068 + hypothetical protein gene gene5098 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05000 S100141_05001 S100141_05001 S100141_05001 167069 167443 + hypothetical protein gene gene5099 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05001 S100141_05002 S100141_05002 S100141_05002 167522 168421 + Subtilisin Hydrolase%3B Protease%3B Serine protease%3B Involved in the generation of beta- and alpha-amylases from the large amylase precursor. Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: pste:PSTEL_00945 subtilisin gene gene5100 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05002 S100141_05003 S100141_05003 S100141_05003 168517 168657 + hypothetical protein gene gene5101 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05003 S100141_05004 S100141_05004 S100141_05004 168611 169090 + hypothetical protein gene gene5102 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05004 S100141_05005 S100141_05005 S100141_05005 169087 169653 + hypothetical protein gene gene5103 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05005 S100141_05006 S100141_05006 S100141_05006 169654 170415 + hypothetical protein gene gene5104 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05006 S100141_05007 S100141_05007 S100141_05007 170400 170633 + hypothetical protein gene gene5105 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05007 S100141_05008 S100141_05008 S100141_05008 170869 171183 + UPF0296 protein Plasmid%3B Belongs to the UPF0296 family gene gene5106 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05008 S100141_05009 S100141_05009 S100141_05009 171205 174726 + DNA-directed DNA polymerase Cytoplasm%3B DNA replication%3B DNA-directed DNA polymerase%3B Nucleotidyltransferase%3B Transferase%3B DNA polymerase III is a complex%2C multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase (By similarity)%3B Belongs to the DNA polymerase type-C family. DnaE subfamily%3B KEGG: cbn:CbC4_0445 DNA polymerase III subunit alpha gene gene5107 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05009 S100141_05010 S100141_05010 S100141_05010 174761 175189 + hypothetical protein gene gene5108 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05010 S100141_05011 S100141_05011 S100141_05011 175341 176414 + Muramidase-2 Antimicrobial%3B Bacteriolytic enzyme%3B Cell cycle%3B Cell division%3B Cell wall biogenesis/degradation%3B Glycosidase%3B Hydrolase%3B Repeat%3B Secreted%3B Septation%3B Signal%3B May work in concert with and potentiate the processive hydrolytic action of muramidase-1%2C which requires binding of the enzyme to non-reducing ends of glycan chains. Hydrolysis in the midst of glycan chains would increase the number of binding sites for muramidase-1. May function in facilitating septum formation and cell separation. Active on M. luteus cell walls and on E. hirae cell wall fractions%2C but not active on E. hirae intact cell walls. Can covalently bind penicillin%3B Belongs to the glycosyl hydrolase 73 family%3B Contains 6 LysM repeats gene gene5109 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05011 S100141_05012 S100141_05012 S100141_05012 176484 176723 + hypothetical protein gene gene5110 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05012 S100141_05013 S100141_05013 S100141_05013 176720 176953 + hypothetical protein gene gene5111 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05013 S100141_05014 S100141_05014 S100141_05014 176917 177159 + hypothetical protein gene gene5112 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05014 S100141_05015 S100141_05015 S100141_05015 177156 177617 + hypothetical protein gene gene5113 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05015 S100141_05016 S100141_05016 S100141_05016 177562 178191 + Guanylate kinase ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Essential for recycling GMP and indirectly%2C cGMP%3B Belongs to the guanylate kinase family%3B Contains 1 guanylate kinase-like domain%3B KEGG: isc:IscW_ISCW011552 guanylate kinase gene gene5114 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05016 S100141_05017 S100141_05017 S100141_05017 178216 179115 - Site-specific DNA-methyltransferase (adenine-specific) KEGG: gsb:GSUB_17215 type I restriction enzyme M protein gene gene5115 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05017 S100141_05018 S100141_05018 S100141_05018 179235 179852 + hypothetical protein gene gene5116 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05018 S100141_05019 S100141_05019 S100141_05019 181012 181125 + hypothetical protein gene gene5117 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05019 S100141_05020 S100141_05020 S100141_05020 181452 181913 - hypothetical protein gene gene5118 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05020 S100141_05021 S100141_05021 S100141_05021 182129 183547 - hypothetical protein gene gene5119 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05021 S100141_05022 S100141_05022 S100141_05022 183528 184007 - hypothetical protein gene gene5120 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05022 S100141_05023 S100141_05023 S100141_05023 184098 185060 - hypothetical protein gene gene5121 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05023 S100141_05024 S100141_05024 S100141_05024 185227 185553 - hypothetical protein gene gene5122 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05024 S100141_05025 S100141_05025 S100141_05025 185704 185862 - hypothetical protein gene gene5123 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05025 S100141_05026 S100141_05026 S100141_05026 185852 187072 - hypothetical protein gene gene5124 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05026 S100141_05027 S100141_05027 S100141_05027 187331 187456 - hypothetical protein gene gene5125 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05027 S100141_05028 S100141_05028 S100141_05028 187440 188576 - Response regulator aspartate phosphatase Hydrolase%3B Protein phosphatase%3B Repeat%3B TPR repeat%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bya:BANAU_1716 response regulator aspartate phosphatase I%3B Acting on ester bonds gene gene5126 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05028 S100141_05029 S100141_05029 S100141_05029 188765 190024 - putative MFS-type transporter YvqJ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene5127 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05029 S100141_05030 S100141_05030 S100141_05030 190218 190682 - Repressor rok Coiled coil%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation. gene gene5128 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05030 S100141_05031 S100141_05031 S100141_05031 190811 191287 - putative antitoxin YezG Coiled coil%3B Probable antitoxin component of a toxin-antitoxin (TA) module. Probably neutralizes the ability to inhibit growth of cognate toxin YeeF. Probably does not have antitoxin activity on other toxins with the LXG toxin domain (Probable) gene gene5129 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05031 S100141_05032 S100141_05032 S100141_05032 191294 193339 - Ribonuclease YxiD Coiled coil%3B Hydrolase%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene5130 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05032 S100141_05033 S100141_05033 S100141_05033 193478 193843 - Replication termination protein DNA-binding%3B Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat (By similarity) gene gene5131 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05033 S100141_05034 S100141_05034 S100141_05034 194470 195468 - hypothetical protein gene gene5132 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05034 S100141_05035 S100141_05035 S100141_05035 196135 196353 + hypothetical protein gene gene5133 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05035 S100141_05036 S100141_05036 S100141_05036 196360 197298 + Flagellin Bacterial flagellum%3B Cell wall%3B Secreted%3B Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Belongs to the bacterial flagellin family gene gene5134 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05036 S100141_05037 S100141_05037 S100141_05037 197522 197815 - hypothetical protein gene gene5135 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05037 S100141_05038 S100141_05038 S100141_05038 197815 198012 - hypothetical protein gene gene5136 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05038 S100141_05039 S100141_05039 S100141_05039 198025 198210 - hypothetical protein gene gene5137 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05039 S100141_05040 S100141_05040 S100141_05040 198203 198523 - hypothetical protein gene gene5138 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05040 S100141_05041 S100141_05041 S100141_05041 198564 198788 - hypothetical protein gene gene5139 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05041 S100141_05042 S100141_05042 S100141_05042 198802 198996 - hypothetical protein gene gene5140 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05042 S100141_05043 S100141_05043 S100141_05043 199059 200399 - DNA-directed DNA polymerase Cytoplasm%3B DNA replication%3B DNA-directed DNA polymerase%3B Nucleotidyltransferase%3B Transferase%3B KEGG: rso:RSc3441 DNA polymerase III subunit beta gene gene5141 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05043 S100141_05044 S100141_05044 S100141_05044 200705 201085 - hypothetical protein gene gene5142 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05044 S100141_05045 S100141_05045 S100141_05045 201264 201548 - hypothetical protein gene gene5143 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05045 S100141_05046 S100141_05046 S100141_05046 201584 205000 - DNA topoisomerase KEGG: psp:PSPPH_0752 DNA topoisomerase III gene gene5144 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05046 S100141_05047 S100141_05047 S100141_05047 96 674 - ComE operon protein Cell membrane%3B Competence%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The comE operon is required for the binding and uptake of transforming DNA. ComEC is required for internalization but is dispensable for DNA binding. To H. influenzae REC2%2C N. gonorrhoeae ComA and E. coli YcaI%3B overlaps another CDS with the same product name gene gene4814 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05047 S100141_05048 S100141_05048 S100141_05048 674 979 - ComE operon protein Cell membrane%3B Competence%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The comE operon is required for the binding and uptake of transforming DNA. ComEC is required for internalization but is dispensable for DNA binding. To H. influenzae REC2%2C N. gonorrhoeae ComA and E. coli YcaI%3B overlaps another CDS with the same product name gene gene4815 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05048 S100141_05049 S100141_05049 S100141_05049 1665 2081 - dCMP deaminase Hydrolase%3B Metal-binding%3B Zinc%3B Dispensable for transformability. Belongs to the cytidine and deoxycytidylate deaminase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: bsu:BSU25580 dCMP deaminase gene gene4816 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05049 S100141_05050 S100141_05050 S100141_05050 2224 2778 - ComE operon protein Cell membrane%3B Competence%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Needed for both DNA binding and transport. It is absolutely required for the uptake of transforming DNA but not for binding. Its role in binding may be indirect. Contains 2 HhH domains gene gene4817 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05050 S100141_05051 S100141_05051 S100141_05051 3034 3633 + ComE operon protein Dispensable for transformability. Not known if it can act as a pyrroline-5-carboxylate reductase. Belongs to the pyrroline-5-carboxylate reductase family gene gene4818 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05051 S100141_05052 S100141_05052 S100141_05052 3750 4505 - 2-polyprenyl-6-hydroxyphenol methylase Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B May be a S-adenosyl-L-methionine (SAM)-dependent methyltransferase. Belongs to the methyltransferase superfamily%3B KEGG: fil:BN1229_v1_1253 2-polyprenyl-6-hydroxyphenyl methylase / 3-demethylubiquinone-9 3-methyltransferase gene gene4819 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05052 S100141_05053 S100141_05053 S100141_05053 4495 4857 - Ribosomal silencing factor RsfS Cytoplasm%3B Repressor%3B Translation regulation%3B Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN)%2C blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes%2C thus repressing translation%3B Belongs to the Iojap/RsfS family gene gene4820 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05053 S100141_05054 S100141_05054 S100141_05054 4871 5215 - Nicotinate-nucleotide adenylyltransferase Contains 1 HD domain%3B KEGG: mput:MPUT9231_3850 nicotinate-nucleotide adenylyltransferase gene gene4821 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05054 S100141_05055 S100141_05055 S100141_05055 5423 5992 - Nicotinate-nucleotide adenylyltransferase ATP-binding%3B NAD%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Pyridine nucleotide biosynthesis%3B Transferase%3B Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)%3B Belongs to the NadD family%3B KEGG: nma:NMA0416 nicotinate-nucleotide adenylyltransferase gene gene4822 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05055 S100141_05056 S100141_05056 S100141_05056 6011 6301 - putative RNA-binding protein YqeI RNA-binding%3B Contains 1 CRM domain gene gene4823 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05056 S100141_05057 S100141_05057 S100141_05057 6295 7131 - Shikimate dehydrogenase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B NADP%3B Oxidoreductase%3B Involved in the biosynthesis of the chorismate%2C which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)%3B Belongs to the shikimate dehydrogenase family%3B KEGG: bli:BL02079 shikimate dehydrogenase gene gene4824 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05057 S100141_05058 S100141_05058 S100141_05058 7151 8077 - uncharacterized protein GTP-binding%3B Nucleotide-binding%3B Binds GTP and GDP. Belongs to the TRAFAC class YlqF/YawG GTPase family%3B Contains 1 CP-type G (guanine nucleotide-binding) domain gene gene4825 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05058 S100141_05059 S100141_05059 S100141_05059 8256 8414 - uncharacterized protein gene gene4826 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05059 S100141_05060 S100141_05060 S100141_05060 8426 8773 - uncharacterized protein gene gene4827 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05060 S100141_05061 S100141_05061 S100141_05061 9398 9553 - hypothetical protein gene gene4828 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05061 S100141_05062 S100141_05062 S100141_05062 9875 10360 - putative lipoprotein YqeF Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal. gene gene4829 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05062 S100141_05063 S100141_05063 S100141_05063 10623 11363 - putative N-acetyltransferase YdfB Acyltransferase%3B Transferase%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK4362 null%3B Transferring groups other than amino-acyl groups gene gene4830 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05063 S100141_05064 S100141_05064 S100141_05064 11400 11669 - uncharacterized protein gene gene4831 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05064 S100141_05065 S100141_05065 S100141_05065 11972 14911 + Formate dehydrogenase 2Fe-2S%3B 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Molybdenum%3B NAD%3B Oxidoreductase%3B Repeat%3B In the C-terminal sectio%3B belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 2Fe-2S ferredoxin-type domain%3B Contains 2 4Fe-4S ferredoxin-type domains%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: bli:BL02109 formate dehydrogenase major subunit gene gene4832 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05065 S100141_05066 S100141_05066 S100141_05066 14933 15325 + uncharacterized protein To A. fulgidus AF1717 gene gene4833 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05066 S100141_05067 S100141_05067 S100141_05067 15486 15722 - hypothetical protein gene gene4834 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05067 S100141_05068 S100141_05068 S100141_05068 15957 16682 + RNA polymerase sigma-K factor DNA-binding%3B Sigma factor%3B Sporulation%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the mother cell. Belongs to the sigma-70 factor family gene gene4835 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05068 S100141_05069 S100141_05069 S100141_05069 16950 17963 - L-threonine 3-dehydrogenase Cytoplasm%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Zinc%3B Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: lsa:LSA0966 null%3B Oxidoreductases gene gene4836 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05069 S100141_05070 S100141_05070 S100141_05070 18582 19334 - Very-long-chain 3-oxoacyl-CoA reductase-like protein Endoplasmic reticulum%3B Membrane%3B NADP%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Probable reductase%2C but unlike KCR1%2C has no beta- ketoacyl-coenzyme A reductase activity%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family gene gene4837 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05070 S100141_05071 S100141_05071 S100141_05071 19663 20448 - Hydroxysteroid 11-beta-dehydrogenase 1-like protein Glycoprotein%3B NADP%3B Oxidoreductase%3B Secreted%3B Signal%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: aci:ACIAD1883 null%3B Oxidoreductases gene gene4838 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05071 S100141_05072 S100141_05072 nemA nemA 20796 21545 - Chanoclavine-I aldehyde reductase Alkaloid metabolism%3B Flavoprotein%3B FMN%3B NADP%3B Oxidoreductase%3B Catalyzes the reduction of chanoclavine-I aldehyde to dihydrochanoclavine-I aldehyde that spontaneously dehydrates to form 6%2C8-dimethyl-6%2C7-didehydroergoline in the biosynthesis pathway of festuclavine%2C a fungal ergot alkaloid. Ergot alkaloids%2C which are produced by endophyte fungi%2C can enhance plant host fitness%2C but also cause livestock toxicosis to host plants%3B Belongs to the NADH:flavin oxidoreductase/NADH oxidase family%3B KEGG: lha:LHA_3033 N-ethylmaleimide reductase%3B Oxidoreductases gene gene4839 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05072 S100141_05073 S100141_05073 S100141_05073 21523 21846 - Artemisinic aldehyde Delta(11(13)) reductase Cytoplasm%3B Flavoprotein%3B FMN%3B NADP%3B Oxidoreductase%3B Involved in the biosynthesis of the antimalarial endoperoxide artemisinin by catalyzing the double bond reduction of (11R)-dihydroartemisinic aldehyde to produce artemisinic aldehyde. Also able to reduce artemisinic alcohol and artemisinic acid to a lesser extent%3B Belongs to the NADH:flavin oxidoreductase/NADH oxidase family%3B KEGG: bgd:bgla_2g10010 N-ethylmaleimide reductase%3B Oxidoreductases gene gene4840 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05073 S100141_05074 S100141_05074 pcaD pcaD 21861 22709 - 3-oxoadipate enol-lactonase Oxidoreductase%3B Peroxidase%3B Belongs to the bacterial non-heme bromo- and chloro- peroxidases family%3B KEGG: mlo:mlr7206 3-oxoadipate enol-lactonase gene gene4841 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05074 S100141_05075 S100141_05075 S100141_05075 22820 23395 - HTH-type transcriptional repressor ComR Copper%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Represses expression of BhsA/ComC by binding to its promoter region in the absence of copper%3B Contains 1 HTH tetR-type DNA-binding domain gene gene4842 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05075 S100141_05076 S100141_05076 S100141_05076 24053 24988 - Alcohol dehydrogenase Mitochondrion%3B Transit peptide%3B Appears to be a potent inhibitor of regeneration following spinal cord injury%3B Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily%3B KEGG: bty:Btoyo_0721 alcohol dehydrogenase gene gene4843 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05076 S100141_05077 S100141_05077 S100141_05077 26081 26395 + RNA polymerase sigma-28 factor DNA-binding%3B Sigma factor%3B Sporulation%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor directs the transcription of crystal protein genes%2C a sporulation-regulated event (By similarity)%3B Belongs to the sigma-70 factor family gene gene4844 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05077 S100141_05078 S100141_05078 S100141_05078 26887 27588 - Lactococcin transport/processing ATP-binding protein LcnC-like ATP-binding%3B Bacteriocin transport%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Protease%3B Protein transport%3B Thiol protease%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the export process of a bacteriocin lactococcin%3B Belongs to the ABC transporter superfamily. HlyB family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain%3B Contains 1 peptidase C39 domain gene gene4845 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05078 S100141_05079 S100141_05079 S100141_05079 27690 28691 - Subtilin transport ATP-binding protein SpaT ATP-binding%3B Bacteriocin transport%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably implicated in the export process of the lantibiotic subtilin. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene4846 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05079 S100141_05080 S100141_05080 S100141_05080 28742 28912 - hypothetical protein gene gene4847 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05080 S100141_05081 S100141_05081 S100141_05081 28927 29268 - hypothetical protein gene gene4848 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05081 S100141_05082 S100141_05082 S100141_05082 29298 29486 - hypothetical protein gene gene4849 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05082 S100141_05083 S100141_05083 S100141_05083 29483 30013 - hypothetical protein gene gene4850 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05083 S100141_05084 S100141_05084 S100141_05084 30217 31374 + Stage II sporulation protein Sporulation. gene gene4851 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05084 S100141_05085 S100141_05085 S100141_05085 31796 32017 - hypothetical protein gene gene4852 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05085 S100141_05086 S100141_05086 S100141_05086 32339 32653 + RNA polymerase sigma-28 factor DNA-binding%3B Sigma factor%3B Sporulation%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor directs the transcription of crystal protein genes%2C a sporulation-regulated event (By similarity)%3B Belongs to the sigma-70 factor family gene gene4853 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05086 S100141_05087 S100141_05087 S100141_05087 32705 33235 - hypothetical protein gene gene4854 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05087 S100141_05088 S100141_05088 S100141_05088 33318 33842 - putative N-acetyltransferase YuaI Acyltransferase%3B Transferase%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: tth:TTC0848 null%3B Transferring groups other than amino-acyl groups gene gene4855 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05088 S100141_05089 S100141_05089 S100141_05089 35093 35467 - UPF0715 membrane protein YwlA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0715 family gene gene4856 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05089 S100141_05090 S100141_05090 S100141_05090 35523 36479 + hypothetical protein gene gene4857 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05090 S100141_05091 S100141_05091 S100141_05091 37435 38745 - hypothetical protein gene gene4858 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05091 S100141_05092 S100141_05092 S100141_05092 39407 40147 - hypothetical protein gene gene4859 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05092 S100141_05093 S100141_05093 S100141_05093 40481 40699 - Hydroxyacylglutathione hydrolase Belongs to the UPF0033 family%3B Contains 1 rhodanese domain%3B KEGG: bst:GYO_2875 hydroxyacylglutathione hydrolase gene gene4860 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05093 S100141_05094 S100141_05094 S100141_05094 40856 41836 - Hydroxyacylglutathione hydrolase KEGG: bst:GYO_2875 hydroxyacylglutathione hydrolase gene gene4861 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05094 S100141_05095 S100141_05095 S100141_05095 42135 43103 - Sulfide:quinone oxidoreductase%2C mitochondrial FAD%3B Flavoprotein%3B Mitochondrion%3B Oxidoreductase%3B Quinone%3B Transit peptide%3B Catalyzes the oxidation of hydrogen sulfide%2C with the help of a quinone%3B Belongs to the SQRD family%3B KEGG: bst:GYO_2876 sulfide:quinone oxidoreductase%3B With a quinone or similar compound as acceptor gene gene4862 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05095 S100141_05096 S100141_05096 S100141_05096 43264 43857 - Oxygen regulatory protein NreC Activator%3B Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated NreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nitrite (nir) reductase operons%2C as well as the putative nitrate transporter gene narT%2C and activates their expression (By similarity)%3B Contains 1 HTH luxR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene4863 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05096 S100141_05097 S100141_05097 S100141_05097 43805 43909 - hypothetical protein gene gene4864 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05097 S100141_05098 S100141_05098 S100141_05098 43884 44543 - Histidine kinase 4Fe-4S%3B ATP-binding%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Kinase%3B Metal-binding%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Two-component regulatory system%3B Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated%2C in the absence of oxygen%2C probably at the conserved histidine residue%2C and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons%2C as well as the putative nitrate transporter gene narT%3B Contains 1 histidine kinase domain%3B KEGG: suh:SAMSHR1132_22200 two-component system%2C NarL family%2C sensor histidine kinase NreB gene gene4865 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05098 S100141_05099 S100141_05099 S100141_05099 44649 44960 - hypothetical protein gene gene4866 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05099 S100141_05100 S100141_05100 S100141_05100 45334 46116 - UPF0721 transmembrane protein YrkJ Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0721 family gene gene4867 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05100 S100141_05101 S100141_05101 S100141_05101 46171 46398 - UPF0033 protein YrkI Belongs to the UPF0033 family%3B KEGG: afe:Lferr_2187 tRNA 2-thiouridine synthesizing protein A%3B Sulfurtransferases gene gene4868 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05101 S100141_05102 S100141_05102 S100141_05102 46430 47056 - Thiosulfate sulfurtransferase Contains 1 rhodanese domain%3B KEGG: hwa:HQ_2288A thiosulfate/3-mercaptopyruvate sulfurtransferase gene gene4869 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05102 S100141_05103 S100141_05103 S100141_05103 47655 48074 - UPF0033 protein YrkF Belongs to the UPF0033 family%3B Contains 1 rhodanese domain gene gene4870 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05103 S100141_05104 S100141_05104 S100141_05104 48017 48226 - UPF0033 protein YrkI Belongs to the UPF0033 family%3B KEGG: afe:Lferr_2187 tRNA 2-thiouridine synthesizing protein A%3B Sulfurtransferases gene gene4871 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05104 S100141_05105 S100141_05105 S100141_05105 48371 48571 - uncharacterized protein overlaps another CDS with the same product name gene gene4872 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05105 S100141_05106 S100141_05106 S100141_05106 48568 48813 - uncharacterized protein KEGG: gca:Galf_0318 tRNA 2-thiouridine synthesizing protein A%3B Sulfurtransferases%3B overlaps another CDS with the same product name gene gene4873 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05106 S100141_05107 S100141_05107 S100141_05107 49141 49233 - hypothetical protein gene gene4874 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05107 S100141_05108 S100141_05108 S100141_05108 49997 50299 - hypothetical protein gene gene4875 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05108 S100141_05109 S100141_05109 S100141_05109 50826 51050 - hypothetical protein gene gene4876 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05109 S100141_05110 S100141_05110 S100141_05110 51980 52279 + Cobalamin import system permease protein BtuC Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Required for corrinoid utilization. Probably part of the ABC transporter complex BtuCDF involved in cobalamin (vitamin B12) import. Probably involved in the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene4877 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05110 S100141_05111 S100141_05111 S100141_05111 52306 52422 - hypothetical protein gene gene4878 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05111 S100141_05112 S100141_05112 S100141_05112 52419 52784 - hypothetical protein gene gene4879 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05112 S100141_05113 S100141_05113 S100141_05113 53004 53240 - hypothetical protein gene gene4880 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05113 S100141_05114 S100141_05114 S100141_05114 53843 54253 - Porphobilinogen synthase Allosteric enzyme%3B Chlorophyll biosynthesis%3B Chloroplast%3B Heme biosynthesis%3B Lyase%3B Magnesium%3B Metal-binding%3B Plastid%3B Porphyrin biosynthesis%3B Transit peptide%3B Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit%2C each at a distinct site%2C and catalyzes their condensation to form porphobilinogen (By similarity)%3B Belongs to the ALAD family%3B KEGG: ype:YPO3771 porphobilinogen synthase%3B overlaps another CDS with the same product name gene gene4881 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05114 S100141_05115 S100141_05115 S100141_05115 54243 54833 - Porphobilinogen synthase Heme biosynthesis%3B Lyase%3B Magnesium%3B Metal-binding%3B Porphyrin biosynthesis%3B Zinc%3B Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit%2C each at a distinct site%2C and catalyzes their condensation to form porphobilinogen (By similarity)%3B Belongs to the ALAD family%3B KEGG: hpy:HP0163 porphobilinogen synthase%3B overlaps another CDS with the same product name gene gene4882 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05115 S100141_05116 S100141_05116 S100141_05116 55316 56269 + Zinc-binding protein AdcA Ion transport%3B Signal%3B Transport%3B Zinc%3B Zinc transport%3B Part of the ATP-driven transport system AdcABC for zinc. Belongs to the bacterial solute-binding protein 9 family gene gene4883 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05116 S100141_05117 S100141_05117 S100141_05117 56306 57019 + putative ABC transporter ATP-binding protein YvfR ATP-binding%3B Hydrolase%3B Nucleotide-binding%3B Transport%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene4884 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05117 S100141_05118 S100141_05118 S100141_05118 56965 57681 + High-affinity zinc uptake system membrane protein ZnuB Cell membrane%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Zinc%3B Zinc transport%3B Part of the high-affinity ABC transporter complex ZnuABC involved in zinc import (Probable). Responsible for the translocation of the substrate across the membrane (By similarity). ZnuABC-mediated zinc transport is required for comF expression and competence development%3B Belongs to the ABC-3 integral membrane protein family gene gene4885 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05118 S100141_05119 S100141_05119 S100141_05119 58461 58961 + 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase Antibiotic resistance%3B Methyltransferase%3B RNA-binding%3B S-adenosyl-L-methionine%3B Transferase%3B Involved in erythromycin resistance. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family%3B KEGG: rhd:R2APBS1_3256 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase gene gene4886 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05119 S100141_05120 S100141_05120 ermC ermC 58949 59245 + 23S rRNA (adenine(2085)-N(6))-dimethyltransferase Antibiotic resistance%3B Methyltransferase%3B RNA-binding%3B S-adenosyl-L-methionine%3B Transferase%3B Involved in erythromycin resistance. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family%3B KEGG: blh:BaLi_c28970 23S rRNA (adenine-N6)-dimethyltransferase gene gene4887 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05120 S100141_05121 S100141_05121 S100141_05121 59331 59720 - 2-hydroxymuconate tautomerase Isomerase%3B Belongs to the 4-oxalocrotonate tautomerase family%3B KEGG: mav:MAV_2790 4-oxalocrotonate tautomerase gene gene4888 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05121 S100141_05122 S100141_05122 S100141_05122 60037 61272 + putative permease Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the GntP permease family gene gene4889 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05122 S100141_05123 S100141_05123 S100141_05123 61418 61522 - hypothetical protein gene gene4890 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05123 S100141_05124 S100141_05124 S100141_05124 61686 61964 - 6-phospho-3-hexuloisomerase Carbohydrate metabolism%3B Detoxification%3B Isomerase%3B Catalyzes the isomerization between 3-hexulose 6- phosphate and fructose 6-phosphate. Together with HxlA%2C may act as a formaldehyde detoxification system. Belongs to the SIS family. PHI subfamily%3B Contains 1 SIS domain%3B KEGG: bli:BL02046 6-phospho-3-hexuloisomerase gene gene4891 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05124 S100141_05125 S100141_05125 S100141_05125 62262 62870 - 3-hexulose-6-phosphate synthase Carbohydrate metabolism%3B Lyase%3B One-carbon metabolism%3B Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate%3B Belongs to the HPS/KGPDC family. HPS subfamily%3B KEGG: eum:ECUMN_2963 3-hexulose-6-phosphate synthase gene gene4892 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05125 S100141_05126 S100141_05126 S100141_05126 63052 63399 - HTH-type transcriptional activator HxlR Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Positive regulator of hxlAB expression. Contains 1 HTH hxlR-type DNA-binding domain gene gene4893 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05126 S100141_05127 S100141_05127 S100141_05127 63734 64375 + Fatty acid desaturase Cell membrane%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsaturated fatty acids%3B Belongs to the fatty acid desaturase family%3B KEGG: bsu:BSU19180 omega-6 fatty acid desaturase (delta-12 desaturase)%3B With oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water gene gene4894 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05127 S100141_05128 S100141_05128 S100141_05128 64849 65184 + Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system DesR/DesK%2C responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase. Acts as a sensor of the membrane fluidity. Probably activates DesR by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: blh:BaLi_c29030 two-component system%2C NarL family%2C sensor histidine kinase DesK gene gene4895 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05128 S100141_05129 S100141_05129 S100141_05129 65254 65958 + Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system DesR/DesK%2C responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase. Acts as a sensor of the membrane fluidity. Probably activates DesR by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bsu:BSU19190 two-component system%2C NarL family%2C sensor histidine kinase DesK gene gene4896 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05129 S100141_05130 S100141_05130 S100141_05130 65978 66430 + Transcriptional regulatory protein DesR Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system DesR/DesK%2C responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase%3B Contains 1 HTH luxR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene4897 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05130 S100141_05131 S100141_05131 S100141_05131 66643 67692 - Thioredoxin-disulfide reductase FAD%3B Flavoprotein%3B NADP%3B Oxidoreductase%3B Belongs to the ferredoxin--NADP reductase type 2 family%3B KEGG: bli:BL02042 thioredoxin reductase (NADPH) gene gene4898 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05131 S100141_05132 S100141_05132 S100141_05132 67982 68425 + Nickel-binding periplasmic protein Nickel%3B Periplasm%3B Signal%3B Transport%3B Involved in a nickel transport system%2C probably represents the nickel binder. Belongs to the bacterial solute-binding protein 5 family gene gene4899 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05132 S100141_05133 S100141_05133 S100141_05133 68492 68677 + Nickel-binding periplasmic protein Nickel%3B Periplasm%3B Signal%3B Transport%3B Involved in a nickel transport system%2C probably represents the nickel binder. Belongs to the bacterial solute-binding protein 5 family%3B overlaps another CDS with the same product name gene gene4900 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05133 S100141_05134 S100141_05134 S100141_05134 68674 69453 + Nickel-binding periplasmic protein Nickel%3B Periplasm%3B Signal%3B Transport%3B Involved in a nickel transport system%2C probably represents the nickel binder. Belongs to the bacterial solute-binding protein 5 family%3B overlaps another CDS with the same product name gene gene4901 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05134 S100141_05135 S100141_05135 S100141_05135 69609 69761 + hypothetical protein gene gene4902 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05135 S100141_05136 S100141_05136 S100141_05136 69785 70093 + Dipeptide transport system permease protein DppB Cell membrane%3B Membrane%3B Peptide transport%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system for dipeptide%3B probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene4903 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05136 S100141_05137 S100141_05137 S100141_05137 70261 70551 + Oligopeptide transport system permease protein AmiC Cell membrane%3B Membrane%3B Peptide transport%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system for oligopeptide%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene4904 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05137 S100141_05138 S100141_05138 S100141_05138 70548 70880 + Oligopeptide transport system permease protein OppC Cell membrane%3B Competence%3B Membrane%3B Peptide transport%3B Protein transport%3B Sporulation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system for oligopeptide%3B probably responsible for the translocation of the substrate across the membrane. Also required for sporulation and competence. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene4905 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05138 S100141_05139 S100141_05139 S100141_05139 70880 71380 + Dipeptide transport system permease protein DppC Cell inner membrane%3B Cell membrane%3B Membrane%3B Peptide transport%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system for dipeptide%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene4906 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05139 S100141_05140 S100141_05140 S100141_05140 71396 71554 + Nickel-transporting ATPase KEGG: bli:BL02421 nickel transport system ATP-binding protein gene gene4907 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05140 S100141_05141 S100141_05141 S100141_05141 71632 72048 + Dipeptide transport ATP-binding protein DppD ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Peptide transport%3B Protein transport%3B Sporulation%3B Transport%3B Part of the binding-protein-dependent transport system for dipeptides. Probably responsible for energy coupling to the transport system. Expressed to facilitate adaptation to nutrient deficiency conditions%2C which also induce sporulation. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene4908 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05141 S100141_05142 S100141_05142 nikE nikE 72801 73085 + Nickel-transporting ATPase KEGG: bli:BL02422 nickel transport system ATP-binding protein gene gene4909 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05142 S100141_05143 S100141_05143 S100141_05143 73371 73925 + putative HTH-type transcriptional regulator YdfL DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH merR-type DNA-binding domain gene gene4910 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05143 S100141_05144 S100141_05144 S100141_05144 73913 74110 + hypothetical protein gene gene4911 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05144 S100141_05145 S100141_05145 S100141_05145 74336 74716 + hypothetical protein gene gene4912 http://www.ncbi.nlm.nih.gov/gene/?term=S100141_05145