locus-tag	class	description
C7M53_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C7M53_00010	COG0592	DNA-directed DNA polymerase activity
C7M53_00015	COG2501	S4 domain
C7M53_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C7M53_00030	COG0187	DNA topoisomerase II activity
C7M53_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7M53_00070	COG0517	IMP dehydrogenase activity
C7M53_00070	COG0516	GMP reductase activity
C7M53_00075	COG1686	Belongs to the peptidase S11 family
C7M53_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
C7M53_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
C7M53_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C7M53_00095	COG1929	Belongs to the glycerate kinase type-1 family
C7M53_00100	COG2610	gluconate transmembrane transporter activity
C7M53_00105	COG3835	regulator
C7M53_00120	COG1428	Deoxynucleoside kinase
C7M53_00125	COG1428	Deoxynucleoside kinase
C7M53_00130	COG3858	chitin binding
C7M53_00130	COG1388	LysM domain
C7M53_00135	COG1335	isochorismatase
C7M53_00140	COG0590	tRNA wobble adenosine to inosine editing
C7M53_00150	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C7M53_00155	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C7M53_00160	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C7M53_00205	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
C7M53_00210	COG3853	Toxic anion resistance protein (TelA)
C7M53_00215	COG1982	Orn Lys Arg decarboxylase major
C7M53_00220	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C7M53_00225	COG3870	Protein conserved in bacteria
C7M53_00230	COG1728	Protein conserved in bacteria
C7M53_00235	COG0470	DNA polymerase III
C7M53_00240	COG1774	PSP1 C-terminal conserved region
C7M53_00245	COG4467	Involved in initiation control of chromosome replication
C7M53_00250	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C7M53_00255	COG2827	Endonuclease containing a URI domain
C7M53_00260	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C7M53_00265	COG2002	toxin-antitoxin pair type II binding
C7M53_00270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M53_00270	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M53_00275	COG0084	hydrolase, TatD family'
C7M53_00280	COG3584	3D domain protein
C7M53_00280	COG3583	domain protein
C7M53_00285	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C7M53_00290	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C7M53_00300	COG4466	Protein conserved in bacteria
C7M53_00310	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C7M53_00315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7M53_00320	COG0251	oxidation-reduction process
C7M53_00325	COG2088	sporulation resulting in formation of a cellular spore
C7M53_00330	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C7M53_00335	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C7M53_00340	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C7M53_00345	COG0193	aminoacyl-tRNA hydrolase activity
C7M53_00355	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C7M53_00360	COG2002	toxin-antitoxin pair type II binding
C7M53_00365	COG2244	polysaccharide biosynthetic process
C7M53_00370	COG3956	TIGRFAM MazG family protein
C7M53_00375	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C7M53_00390	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C7M53_00395	COG1098	S1 RNA binding domain
C7M53_00410	COG2208	phosphoserine phosphatase activity
C7M53_00415	COG2304	oxidoreductase activity
C7M53_00420	COG0515	serine threonine protein kinase
C7M53_00425	COG0037	tRNA processing
C7M53_00435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7M53_00440	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
C7M53_00445	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C7M53_00450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7M53_00455	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7M53_00465	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7M53_00470	COG0512	Glutamine amidotransferase of anthranilate synthase
C7M53_00475	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M53_00480	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C7M53_00485	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C7M53_00490	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C7M53_00495	COG1396	sequence-specific DNA binding
C7M53_0050	COG1793	dna ligase
C7M53_00500	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7M53_00505	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C7M53_00535	COG4463	regulation of RNA biosynthetic process
C7M53_00540	COG3880	PFAM UvrB UvrC protein
C7M53_00545	COG3869	Catalyzes the specific phosphorylation of arginine residues in
C7M53_00550	COG0542	response to heat
C7M53_00555	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C7M53_00560	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
C7M53_00565	COG4956	integral membrane protein (PIN domain superfamily)
C7M53_00570	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C7M53_00575	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
C7M53_00580	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C7M53_00585	COG1045	serine acetyltransferase
C7M53_00590	COG0215	cysteine-tRNA ligase activity
C7M53_00595	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C7M53_00600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7M53_00605	COG3688	RNA-binding protein containing a PIN domain
C7M53_00615	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7M53_00625	COG0250	Participates in transcription elongation, termination and antitermination
C7M53_00630	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C7M53_00635	COG0081	regulation of translation
C7M53_00640	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C7M53_00645	COG0222	ribosome binding
C7M53_00650	COG2813	Specifically methylates the guanine in position
C7M53_00655	COG0085	RNA polymerase activity
C7M53_00660	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C7M53_00665	COG1358	cellular component organization or biogenesis
C7M53_00670	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C7M53_00675	COG0049	tRNA binding
C7M53_00680	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C7M53_00685	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C7M53_00690	COG0051	transcription antitermination factor activity, RNA binding
C7M53_00695	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C7M53_00700	COG0088	Forms part of the polypeptide exit tunnel
C7M53_00705	COG0089	rRNA binding
C7M53_00710	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C7M53_00715	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C7M53_00720	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C7M53_00725	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C7M53_00730	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C7M53_00735	COG0255	Belongs to the universal ribosomal protein uL29 family
C7M53_00740	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C7M53_00745	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C7M53_00750	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C7M53_00755	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C7M53_00760	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C7M53_00765	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C7M53_00770	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C7M53_00775	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C7M53_00780	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C7M53_00785	COG1841	ribosomal large subunit assembly
C7M53_00790	COG0200	Binds to the 23S rRNA
C7M53_00795	COG0201	protein transport
C7M53_00800	COG0563	adenylate kinase activity
C7M53_00805	COG0024	Methionine aminopeptidase
C7M53_00810	COG2163	COG2163 Ribosomal protein L14E L6E L27E
C7M53_00815	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C7M53_00820	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C7M53_00825	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C7M53_00830	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C7M53_00835	COG0202	RNA polymerase activity
C7M53_00840	COG0203	ribosomal protein L17
C7M53_00845	COG1122	ATPase activity
C7M53_00850	COG1122	ATPase activity
C7M53_00855	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C7M53_00860	COG0101	tRNA pseudouridine synthase activity
C7M53_00865	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C7M53_00870	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C7M53_00875	COG2318	DinB family
C7M53_00885	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M53_00890	COG0489	protein tyrosine kinase activity
C7M53_00900	COG2194	sulfuric ester hydrolase activity
C7M53_00905	COG0726	polysaccharide deacetylase
C7M53_00935	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M53_00945	COG0385	Bile acid
C7M53_00960	COG3876	Protein conserved in bacteria
C7M53_00965	COG1472	Belongs to the glycosyl hydrolase 3 family
C7M53_00970	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M53_00975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M53_00975	COG1263	PTS System
C7M53_00980	COG1737	Transcriptional regulator
C7M53_00985	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C7M53_00990	COG1683	Conserved Protein
C7M53_01025	COG1595	DNA-templated transcription, initiation
C7M53_01030	COG5662	AntiSigma factor
C7M53_01035	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C7M53_01040	COG4856	YbbR-like protein
C7M53_01045	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7M53_01050	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C7M53_01070	COG1725	Transcriptional regulator
C7M53_01075	COG0640	Transcriptional regulator
C7M53_01080	COG2814	Major facilitator Superfamily
C7M53_01090	COG1132	(ABC) transporter
C7M53_01095	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C7M53_01120	COG1011	Hydrolase
C7M53_01125	COG1113	amino acid transport
C7M53_01130	COG2851	Citrate transporter
C7M53_01135	COG3181	Tripartite tricarboxylate transporter family receptor
C7M53_01140	COG4565	transcriptional regulatory protein
C7M53_01145	COG3290	protein histidine kinase activity
C7M53_01160	COG2211	Major facilitator Superfamily
C7M53_01180	COG1331	Highly conserved protein containing a thioredoxin domain
C7M53_01190	COG0477	Major facilitator Superfamily
C7M53_01210	COG1283	sodium-dependent phosphate transmembrane transporter activity
C7M53_01215	COG4682	membrane
C7M53_01245	COG1917	Cupin 2, conserved barrel domain protein
C7M53_01245	COG2207	Transcriptional regulator
C7M53_01265	COG0371	Dehydrogenase
C7M53_01270	COG0840	transmembrane signaling receptor activity
C7M53_01275	COG4213	ABC transporter substrate-binding protein
C7M53_01290	COG4257	antibiotic catabolic process
C7M53_01300	COG0833	amino acid
C7M53_01305	COG2040	homocysteine
C7M53_01315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M53_01315	COG2190	(PTS) system
C7M53_01315	COG1263	PTS System
C7M53_01320	COG0789	Transcriptional regulator
C7M53_01325	COG2323	membrane
C7M53_01340	COG2205	protein histidine kinase activity
C7M53_01345	COG1115	amino acid carrier protein
C7M53_01350	COG2066	Belongs to the glutaminase family
C7M53_01355	COG4191	Histidine kinase
C7M53_01360	COG0784	Response regulator, receiver
C7M53_01385	COG3540	Alkaline phosphatase
C7M53_01390	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7M53_01395	COG0805	protein transport
C7M53_01400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7M53_01405	COG1012	belongs to the aldehyde dehydrogenase family
C7M53_01410	COG2271	Major facilitator Superfamily
C7M53_01415	COG4948	Mandelate Racemase Muconate Lactonizing
C7M53_01420	COG2186	Transcriptional regulator
C7M53_01425	COG2721	sulfolactate sulfo-lyase activity
C7M53_01430	COG0745	RESPONSE REGULATOR receiver
C7M53_01435	COG2205	protein histidine kinase activity
C7M53_01465	COG3173	Aminoglycoside phosphotransferase
C7M53_01470	COG1846	Transcriptional regulator
C7M53_01475	COG0318	PFAM AMP-dependent synthetase and ligase
C7M53_01500	COG0789	Transcriptional regulator
C7M53_01525	COG0697	spore germination
C7M53_01530	COG1714	RDD family
C7M53_01535	COG3012	SEC-C Motif Domain Protein
C7M53_01535	COG1405	negative regulation of cell septum assembly
C7M53_01565	COG0583	DNA-binding transcription factor activity
C7M53_01570	COG1942	4-Oxalocrotonate Tautomerase
C7M53_01575	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_01590	COG1288	antiporter activity
C7M53_01600	COG0456	acetyltransferase
C7M53_01610	COG1164	Oligoendopeptidase f
C7M53_01615	COG2261	transglycosylase associated protein
C7M53_01625	COG0247	lactate metabolic process
C7M53_01630	COG0277	FAD linked oxidase domain protein
C7M53_01635	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M53_01640	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7M53_01645	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M53_01650	COG1486	melibiose metabolic process
C7M53_01660	COG3394	polysaccharide catabolic process
C7M53_01675	COG3591	Belongs to the peptidase S1B family
C7M53_01680	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_01690	COG1595	DNA-templated transcription, initiation
C7M53_0170	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M53_0170	COG0072	phenylalanine-tRNA ligase activity
C7M53_01700	COG3773	Cell wall hydrolase
C7M53_01705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M53_01710	COG0791	NLP P60 protein
C7M53_01710	COG3883	PFAM NLP P60 protein
C7M53_01720	COG1131	(ABC) transporter
C7M53_01725	COG1309	transcriptional regulator
C7M53_01745	COG2310	stress, protein
C7M53_01750	COG2310	stress, protein
C7M53_01755	COG2310	stress, protein
C7M53_01760	COG0861	Integral membrane protein TerC family
C7M53_01780	COG3853	Toxic anion resistance protein (TelA)
C7M53_01785	COG0785	Cytochrome C biogenesis protein
C7M53_01795	COG0789	Transcriptional regulator
C7M53_01800	COG2223	nitrite transmembrane transporter activity
C7M53_01805	COG0039	L-malate dehydrogenase activity
C7M53_01810	COG1620	l-lactate permease
C7M53_01815	COG1280	lysine exporter protein (LysE YggA)
C7M53_01820	COG1113	amino acid transport
C7M53_01825	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C7M53_01830	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C7M53_01835	COG3541	Predicted nucleotidyltransferase
C7M53_01840	COG0506	proline dehydrogenase activity
C7M53_01845	COG1012	belongs to the aldehyde dehydrogenase family
C7M53_01850	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M53_01855	COG2508	Transcriptional regulator
C7M53_01860	COG3689	TIGRFAM TIGR03943 family protein
C7M53_01865	COG0701	Predicted permease
C7M53_01870	COG3458	cephalosporin-C deacetylase activity
C7M53_01890	COG0765	amino acid transport
C7M53_01895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M53_01900	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7M53_01910	COG2723	6-phospho-beta-galactosidase activity
C7M53_01920	COG3209	COG3209 Rhs family protein
C7M53_01925	COG0515	serine threonine protein kinase
C7M53_01925	COG3266	domain, Protein
C7M53_01935	COG5444	nuclease activity
C7M53_01960	COG1176	ABC-type spermidine putrescine transport system, permease component I
C7M53_01965	COG1177	transmembrane transport
C7M53_01970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M53_01975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M53_01980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M53_01985	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
C7M53_01990	COG0697	spore germination
C7M53_01995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M53_02005	COG2819	hydrolase of the alpha beta superfamily
C7M53_02015	COG2364	Membrane
C7M53_02025	COG1131	(ABC) transporter
C7M53_02050	COG1126	abc transporter atp-binding protein
C7M53_02055	COG0765	amino acid transport
C7M53_02060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M53_02065	COG3829	transcription factor binding
C7M53_02070	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C7M53_02075	COG0833	amino acid
C7M53_02080	COG0010	Belongs to the arginase family
C7M53_02085	COG0583	DNA-binding transcription factor activity
C7M53_02090	COG0163	prenyltransferase activity
C7M53_02095	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C7M53_02145	COG5444	nuclease activity
C7M53_02165	COG2972	Histidine kinase
C7M53_02170	COG4753	response regulator
C7M53_02170	COG2207	Transcriptional regulator
C7M53_02175	COG4213	ABC transporter substrate-binding protein
C7M53_02185	COG4214	carbohydrate transport
C7M53_02190	COG2271	Major facilitator Superfamily
C7M53_02195	COG1846	Transcriptional regulator
C7M53_02195	COG0456	acetyltransferase
C7M53_02200	COG1874	Beta-galactosidase
C7M53_02205	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
C7M53_02210	COG3104	oligopeptide transport
C7M53_02215	COG5434	Belongs to the glycosyl hydrolase 28 family
C7M53_02225	COG0697	spore germination
C7M53_02235	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C7M53_02240	COG0789	Transcriptional regulator
C7M53_02245	COG1136	(ABC) transporter
C7M53_02250	COG0577	efflux transmembrane transporter activity
C7M53_02255	COG0745	RESPONSE REGULATOR receiver
C7M53_02260	COG3850	Histidine kinase
C7M53_02260	COG5002	protein histidine kinase activity
C7M53_02265	COG0840	transmembrane signaling receptor activity
C7M53_02270	COG0527	aspartate kinase activity
C7M53_02275	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M53_02280	COG4605	iron ion homeostasis
C7M53_02285	COG4604	ABC transporter, ATP-binding protein
C7M53_02290	COG4607	ABC-type enterochelin transport system periplasmic component
C7M53_02295	COG2814	Major facilitator Superfamily
C7M53_02300	COG1309	transcriptional regulator
C7M53_02310	COG0778	Nitroreductase
C7M53_02315	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C7M53_02320	COG0640	Transcriptional regulator
C7M53_02325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M53_02330	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C7M53_02335	COG0531	amino acid
C7M53_02340	COG1012	belongs to the aldehyde dehydrogenase family
C7M53_02345	COG0697	spore germination
C7M53_02355	COG4549	nuclear export factor GLE1
C7M53_02360	COG1276	copper resistance
C7M53_02360	COG2372	response to copper ion
C7M53_02365	COG1349	DNA-binding transcription factor activity
C7M53_02370	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7M53_02375	COG0243	molybdopterin cofactor binding
C7M53_02380	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7M53_02385	COG2146	nitrite reductase [NAD(P)H] activity
C7M53_02390	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C7M53_02390	COG1587	Uroporphyrinogen-III synthase
C7M53_02395	COG1802	Transcriptional regulator
C7M53_02400	COG0471	metal ion transport
C7M53_02405	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7M53_02410	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7M53_02425	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M53_02440	COG3959	Transketolase, thiamine diphosphate binding domain
C7M53_02445	COG3958	Transketolase
C7M53_02450	COG0561	phosphatase activity
C7M53_02455	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
C7M53_02460	COG1914	H( )-stimulated, divalent metal cation uptake system
C7M53_02465	COG4336	lyase activity
C7M53_02470	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C7M53_02475	COG1984	allophanate hydrolase subunit 2
C7M53_02480	COG1414	Transcriptional regulator
C7M53_02485	COG2755	lipolytic protein G-D-S-L family
C7M53_02490	COG2213	PTS system mannitol-specific
C7M53_02495	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M53_02500	COG0246	Mannitol dehydrogenase
C7M53_02505	COG3711	transcriptional antiterminator
C7M53_02510	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_02515	COG1917	Cupin 2, conserved barrel domain protein
C7M53_02525	COG3871	stress protein (general stress protein 26)
C7M53_02535	COG1316	TRANSCRIPTIONal
C7M53_02540	COG2814	Major facilitator Superfamily
C7M53_02550	COG1522	sequence-specific DNA binding
C7M53_02555	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7M53_02555	COG0551	DNA topoisomerase type I activity
C7M53_02560	COG0531	amino acid
C7M53_02565	COG0028	Belongs to the TPP enzyme family
C7M53_02570	COG3397	chitin binding
C7M53_02585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M53_02590	COG1914	H( )-stimulated, divalent metal cation uptake system
C7M53_02595	COG2261	transglycosylase associated protein
C7M53_02600	COG1027	Aspartate ammonia-lyase
C7M53_02610	COG4876	unkown
C7M53_02615	COG2217	Heavy metal translocating P-type atpase
C7M53_02625	COG0662	Cupin 2, conserved barrel domain protein
C7M53_02630	COG3729	General stress protein
C7M53_02635	COG0628	permease
C7M53_02640	COG1301	dicarboxylic acid transport
C7M53_02645	COG1131	(ABC) transporter
C7M53_02650	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M53_02660	COG1960	acyl-CoA dehydrogenase activity
C7M53_02675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M53_02680	COG1181	Belongs to the D-alanine--D-alanine ligase family
C7M53_02685	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7M53_02695	COG0513	Belongs to the DEAD box helicase family
C7M53_02700	COG3402	PFAM membrane-flanked domain
C7M53_02705	COG3428	Bacterial PH domain
C7M53_02710	COG0705	Rhomboid family
C7M53_02715	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C7M53_02720	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7M53_02725	COG0864	Transcriptional regulator
C7M53_02730	COG2337	Toxic component of a toxin-antitoxin (TA) module
C7M53_02735	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M53_02740	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M53_02745	COG2172	sigma factor antagonist activity
C7M53_02750	COG2208	phosphoserine phosphatase activity
C7M53_02760	COG2172	sigma factor antagonist activity
C7M53_02765	COG1191	sigma factor activity
C7M53_02770	COG2208	phosphoserine phosphatase activity
C7M53_02775	COG2183	response to ionizing radiation
C7M53_02780	COG1309	transcriptional regulator
C7M53_02785	COG1033	growth of symbiont in host cell
C7M53_02785	COG2409	Drug exporters of the RND superfamily
C7M53_02795	COG3091	SprT-like family
C7M53_02840	COG1476	TRANSCRIPTIONal
C7M53_02845	COG3239	Fatty acid desaturase
C7M53_02850	COG1278	Cold shock
C7M53_02855	COG1063	alcohol dehydrogenase
C7M53_02865	COG2364	Membrane
C7M53_02870	COG1846	Transcriptional regulator
C7M53_02875	COG0456	acetyltransferase
C7M53_02880	COG2808	Putative FMN-binding domain
C7M53_02890	COG1733	regulation of RNA biosynthetic process
C7M53_02895	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M53_02905	COG0583	DNA-binding transcription factor activity
C7M53_02920	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
C7M53_02925	COG1113	amino acid transport
C7M53_02940	COG1595	DNA-templated transcription, initiation
C7M53_02950	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C7M53_02950	COG2755	lipolytic protein G-D-S-L family
C7M53_02955	COG2814	Major facilitator Superfamily
C7M53_02960	COG0745	RESPONSE REGULATOR receiver
C7M53_02960	COG2972	Histidine kinase
C7M53_02965	COG3279	Response regulator of the LytR AlgR family
C7M53_02975	COG3764	Sortase (surface protein transpeptidase)
C7M53_02980	COG2814	Major facilitator Superfamily
C7M53_03080	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C7M53_03085	COG0802	atpase or kinase
C7M53_03090	COG1214	PFAM Peptidase M22, glycoprotease
C7M53_03095	COG0456	acetyltransferase
C7M53_03100	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C7M53_03105	COG0488	(ABC) transporter
C7M53_03110	COG0315	cyclic pyranopterin monophosphate synthase activity
C7M53_03115	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
C7M53_03120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7M53_03125	COG0805	protein transport
C7M53_03135	COG1266	CAAX protease self-immunity
C7M53_03140	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C7M53_03145	COG0459	protein refolding
C7M53_03175	COG2720	vancomycin resistance protein
C7M53_03190	COG2135	peptidase activity
C7M53_03200	COG1309	transcriptional regulator
C7M53_03205	COG0574	Belongs to the PEP-utilizing enzyme family
C7M53_03205	COG3848	Pyruvate phosphate dikinase
C7M53_03215	COG3189	MarR family transcriptional regulator
C7M53_03220	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
C7M53_03225	COG2272	Belongs to the type-B carboxylesterase lipase family
C7M53_03230	COG2814	Major facilitator Superfamily
C7M53_03235	COG1842	Phage shock protein A
C7M53_03240	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7M53_03245	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C7M53_03250	COG4260	virion core protein, lumpy skin disease virus
C7M53_03260	COG1378	Sugar-specific transcriptional regulator TrmB
C7M53_03265	COG1280	lysine exporter protein (LysE YggA)
C7M53_03270	COG3339	Conserved Protein
C7M53_03275	COG0772	Belongs to the SEDS family
C7M53_03280	COG0772	Belongs to the SEDS family
C7M53_03305	COG0726	polysaccharide deacetylase
C7M53_03315	COG1609	Transcriptional regulator
C7M53_03320	COG0366	Alpha amylase catalytic
C7M53_03325	COG2182	Extracellular solute-binding protein
C7M53_03330	COG1175	transmembrane transport
C7M53_03335	COG3833	ABC-type maltose transport systems, permease component
C7M53_03340	COG5521	maltodextrose utilization protein MalA
C7M53_03345	COG1554	hydrolase, family 65, central catalytic
C7M53_03350	COG0366	Alpha amylase catalytic
C7M53_03355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7M53_03360	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C7M53_03365	COG1846	Transcriptional regulator
C7M53_03380	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C7M53_03385	COG0823	Involved in the tonB-independent uptake of proteins
C7M53_03420	COG0702	epimerase
C7M53_03430	COG2132	Multicopper oxidase
C7M53_03445	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7M53_03450	COG0714	Associated with various cellular activities
C7M53_03455	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
C7M53_03460	COG1305	Transglutaminase-like
C7M53_03465	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C7M53_03465	COG0519	Catalyzes the synthesis of GMP from XMP
C7M53_03475	COG2252	PERMEase
C7M53_03490	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
C7M53_03500	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C7M53_03505	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C7M53_03510	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C7M53_03515	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C7M53_03520	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7M53_03525	COG0047	phosphoribosylformylglycinamidine synthase activity
C7M53_03530	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7M53_03535	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C7M53_03540	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C7M53_03545	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C7M53_03550	COG0138	bifunctional purine biosynthesis protein purh
C7M53_03555	COG0151	Belongs to the GarS family
C7M53_03565	COG2124	cytochrome p450
C7M53_03585	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C7M53_03590	COG1470	cell adhesion involved in biofilm formation
C7M53_03595	COG4496	protein, YerC YecD
C7M53_03600	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
C7M53_03605	COG0210	DNA helicase
C7M53_03610	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C7M53_03615	COG4851	CamS sex pheromone cAM373 precursor
C7M53_03620	COG2188	Transcriptional regulator
C7M53_03640	COG1735	metal-dependent hydrolase with the TIM-barrel fold
C7M53_03645	COG0626	cystathionine gamma-synthase activity
C7M53_03650	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C7M53_03655	COG3457	Alanine racemase
C7M53_03660	COG0363	glucosamine-6-phosphate deaminase activity
C7M53_03665	COG1285	pathogenesis
C7M53_03670	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M53_03675	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7M53_03680	COG0154	amidase activity
C7M53_03685	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7M53_03700	COG4124	Belongs to the glycosyl hydrolase 26 family
C7M53_03705	COG1309	transcriptional regulator
C7M53_03710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7M53_03720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M53_03725	COG1957	nucleoside hydrolase
C7M53_03730	COG1597	lipid kinase activity
C7M53_03735	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7M53_03745	COG1263	PTS System
C7M53_03745	COG2190	(PTS) system
C7M53_03745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M53_03750	COG2723	6-phospho-beta-galactosidase activity
C7M53_03755	COG3711	transcriptional antiterminator
C7M53_03760	COG0457	Tetratricopeptide repeat
C7M53_03780	COG0217	transcriptional regulatory protein
C7M53_03795	COG1012	belongs to the aldehyde dehydrogenase family
C7M53_03800	COG0840	transmembrane signaling receptor activity
C7M53_03805	COG0471	metal ion transport
C7M53_03810	COG0488	(ABC) transporter
C7M53_03815	COG1469	GTP cyclohydrolase I activity
C7M53_03830	COG0523	cobalamin synthesis protein
C7M53_03835	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
C7M53_03840	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7M53_03845	COG0156	8-amino-7-oxononanoate synthase activity
C7M53_03850	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C7M53_03855	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C7M53_03860	COG2124	cytochrome p450
C7M53_03870	COG0789	Transcriptional regulator
C7M53_03875	COG2814	Major facilitator Superfamily
C7M53_03880	COG0488	(ABC) transporter
C7M53_03885	COG0513	Belongs to the DEAD box helicase family
C7M53_03890	COG2130	NADP-dependent
C7M53_03905	COG0471	metal ion transport
C7M53_03920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M53_03930	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
C7M53_03935	COG5658	integral membrane protein
C7M53_03940	COG0640	Transcriptional regulator
C7M53_03945	COG1254	Belongs to the acylphosphatase family
C7M53_03950	COG2258	MOSC domain
C7M53_03960	COG0024	Methionine aminopeptidase
C7M53_03965	COG1368	sulfuric ester hydrolase activity
C7M53_03980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M53_03980	COG1263	PTS System
C7M53_03985	COG0366	Alpha amylase catalytic
C7M53_03990	COG2188	Transcriptional regulator
C7M53_04015	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7M53_04020	COG1045	serine acetyltransferase
C7M53_04025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M53_04035	COG1215	transferase activity, transferring glycosyl groups
C7M53_04040	COG0463	Glycosyl transferase, family 2
C7M53_04040	COG0457	Tetratricopeptide repeat
C7M53_04050	COG0673	inositol 2-dehydrogenase activity
C7M53_04065	COG1733	regulation of RNA biosynthetic process
C7M53_04070	COG0778	Nitroreductase
C7M53_04075	COG0737	Belongs to the 5'-nucleotidase family
C7M53_04080	COG0693	protein deglycase activity
C7M53_04085	COG4840	Belongs to the UPF0435 family
C7M53_04090	COG1115	amino acid carrier protein
C7M53_04095	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7M53_04100	COG4980	gas vesicle protein
C7M53_04105	COG1295	ribonuclease BN
C7M53_04110	COG0477	Major facilitator Superfamily
C7M53_04120	COG0387	Pfam Sodium calcium exchanger
C7M53_04130	COG0535	radical SAM domain protein
C7M53_04140	COG0726	polysaccharide deacetylase
C7M53_04145	COG0371	Dehydrogenase
C7M53_04155	COG0598	Magnesium transport protein CorA
C7M53_04160	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C7M53_04165	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7M53_04170	COG4637	Psort location Cytoplasmic, score
C7M53_04195	COG1819	glycosyl
C7M53_04205	COG0477	Major facilitator Superfamily
C7M53_04210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M53_04210	COG1263	PTS System
C7M53_04215	COG3711	transcriptional antiterminator
C7M53_04220	COG0288	reversible hydration of carbon dioxide
C7M53_04225	COG3002	Belongs to the UPF0753 family
C7M53_04230	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7M53_04235	COG5609	conserved protein (DUF2294)
C7M53_04245	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7M53_04250	COG0022	dehydrogenase e1 component
C7M53_04255	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M53_04260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M53_04265	COG3284	Transcriptional regulator
C7M53_04270	COG1742	UPF0060 membrane protein
C7M53_04275	COG1486	melibiose metabolic process
C7M53_04280	COG1737	Transcriptional regulator
C7M53_04285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M53_04285	COG1263	PTS System
C7M53_04300	COG1733	regulation of RNA biosynthetic process
C7M53_04305	COG2259	Doxx family
C7M53_04310	COG2514	catechol 2,3-dioxygenase activity
C7M53_04325	COG2207	Transcriptional regulator
C7M53_04325	COG1917	Cupin 2, conserved barrel domain protein
C7M53_04330	COG1653	transport
C7M53_04335	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7M53_04340	COG1051	belongs to the nudix hydrolase family
C7M53_04350	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C7M53_04350	COG0392	lysyltransferase activity
C7M53_04355	COG0384	phenazine biosynthesis protein PhzF
C7M53_04360	COG0778	Nitroreductase
C7M53_04380	COG1090	epimerase
C7M53_04385	COG2137	regulation of response to DNA damage stimulus
C7M53_04415	COG0463	Glycosyl transferase, family 2
C7M53_04425	COG4485	Bacterial membrane protein, YfhO
C7M53_04430	COG1988	membrane-bound metal-dependent
C7M53_04435	COG1194	a g-specific adenine glycosylase
C7M53_04445	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_04460	COG3557	Belongs to the UPF0374 family
C7M53_04465	COG1132	(ABC) transporter
C7M53_04470	COG0444	Belongs to the ABC transporter superfamily
C7M53_04475	COG4608	Belongs to the ABC transporter superfamily
C7M53_04480	COG0747	negative chemotaxis
C7M53_04495	COG4129	membrane
C7M53_04500	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C7M53_04505	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C7M53_04510	COG0735	belongs to the Fur family
C7M53_04620	COG0457	Tetratricopeptide repeat
C7M53_04665	COG5444	nuclease activity
C7M53_04670	COG0457	Tetratricopeptide repeat
C7M53_04675	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C7M53_04685	COG0710	3-dehydroquinate dehydratase activity
C7M53_04690	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
C7M53_04695	COG1116	anion transmembrane transporter activity
C7M53_04700	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7M53_04705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7M53_04710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M53_04720	COG1476	TRANSCRIPTIONal
C7M53_04730	COG1131	(ABC) transporter
C7M53_04750	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C7M53_04760	COG3382	B3 4 domain protein
C7M53_04765	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C7M53_04775	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C7M53_04780	COG0789	Transcriptional regulator
C7M53_04785	COG1664	Polymer-forming cytoskeletal
C7M53_04795	COG2766	serine protein kinase
C7M53_04800	COG2718	Belongs to the UPF0229 family
C7M53_04810	COG1566	PFAM secretion protein HlyD family protein
C7M53_04815	COG2814	Major facilitator Superfamily
C7M53_04820	COG0655	NAD(P)H dehydrogenase (quinone) activity
C7M53_04840	COG1131	(ABC) transporter
C7M53_04845	COG1131	(ABC) transporter
C7M53_04850	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M53_04855	COG1278	Cold shock
C7M53_04860	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7M53_04865	COG2011	ABC-type metal ion transport system permease component
C7M53_04870	COG1464	Belongs to the NlpA lipoprotein family
C7M53_04875	COG1823	symporter activity
C7M53_04900	COG5577	PFAM Coat F domain
C7M53_04905	COG5002	protein histidine kinase activity
C7M53_04910	COG1525	nuclease
C7M53_04910	COG4085	toxin activity
C7M53_04910	COG0737	Belongs to the 5'-nucleotidase family
C7M53_04915	COG3764	Sortase (surface protein transpeptidase)
C7M53_04920	COG0564	pseudouridine synthase activity
C7M53_04930	COG0517	IMP dehydrogenase activity
C7M53_04935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7M53_04940	COG3153	acetyltransferase
C7M53_04940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7M53_04945	COG0488	(ABC) transporter
C7M53_04955	COG2116	formate transmembrane transporter activity
C7M53_04960	COG0679	Auxin Efflux Carrier
C7M53_04965	COG0604	alcohol dehydrogenase
C7M53_04970	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C7M53_04975	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7M53_04980	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C7M53_04985	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C7M53_04990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7M53_05005	COG2203	Gaf domain
C7M53_05005	COG4585	Histidine kinase
C7M53_05010	COG2197	response regulator
C7M53_05015	COG0431	NADPH-dependent FMN reductase
C7M53_05030	COG1959	2 iron, 2 sulfur cluster binding
C7M53_05035	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7M53_05035	COG1017	nitric oxide dioxygenase activity
C7M53_05040	COG2719	SpoVR family
C7M53_05045	COG0791	NLP P60 protein
C7M53_05045	COG1388	LysM domain
C7M53_05050	COG0583	DNA-binding transcription factor activity
C7M53_05055	COG0372	Belongs to the citrate synthase family
C7M53_05060	COG2133	pyrroloquinoline quinone binding
C7M53_05065	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_05070	COG0733	neurotransmitter:sodium symporter activity
C7M53_05080	COG2207	Transcriptional regulator
C7M53_05080	COG3708	Transcriptional regulator
C7M53_05105	COG1595	DNA-templated transcription, initiation
C7M53_05110	COG0662	Cupin 2, conserved barrel domain protein
C7M53_05120	COG0204	Acyl-transferase
C7M53_05125	COG3152	Membrane
C7M53_05135	COG1309	transcriptional regulator
C7M53_05140	COG1253	flavin adenine dinucleotide binding
C7M53_05145	COG0789	Transcriptional regulator
C7M53_05150	COG1253	flavin adenine dinucleotide binding
C7M53_05170	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7M53_05175	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7M53_05180	COG0584	glycerophosphoryl diester phosphodiesterase
C7M53_05190	COG0668	transmembrane transport
C7M53_05195	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C7M53_05210	COG0726	polysaccharide deacetylase
C7M53_05220	COG1757	Na H antiporter
C7M53_05225	COG2017	converts alpha-aldose to the beta-anomer
C7M53_05250	COG0589	response to stress
C7M53_05255	COG1132	(ABC) transporter
C7M53_05260	COG1132	(ABC) transporter
C7M53_05265	COG0702	epimerase
C7M53_05280	COG3842	ATPase activity
C7M53_05285	COG2508	Transcriptional regulator
C7M53_05295	COG0189	ligase activity
C7M53_05300	COG0189	ligase activity
C7M53_05305	COG4399	Belongs to the UPF0754 family
C7M53_05310	COG3679	Belongs to the UPF0342 family
C7M53_05325	COG0561	phosphatase activity
C7M53_05330	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7M53_05335	COG0475	glutathione-regulated potassium exporter activity
C7M53_05340	COG0490	domain, Protein
C7M53_05350	COG1024	Enoyl-CoA hydratase
C7M53_05355	COG0457	Tetratricopeptide repeat
C7M53_05370	COG4152	abc transporter atp-binding protein
C7M53_05375	COG1668	transmembrane transport
C7M53_05380	COG0420	3'-5' exonuclease activity
C7M53_05385	COG4717	serine-type aminopeptidase activity
C7M53_05390	COG3481	metal-dependent phosphohydrolase, HD sub domain
C7M53_05400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7M53_05430	COG1846	Transcriptional regulator
C7M53_05435	COG4980	gas vesicle protein
C7M53_05450	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C7M53_05455	COG0537	adenosine 5'-monophosphoramidase activity
C7M53_05465	COG1131	(ABC) transporter
C7M53_05470	COG4473	ABC transporter
C7M53_05480	COG1473	amidohydrolase
C7M53_05490	COG2329	Antibiotic biosynthesis monooxygenase
C7M53_05495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M53_05500	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C7M53_05515	COG1309	transcriptional regulator
C7M53_05520	COG1511	domain protein
C7M53_05530	COG1363	Peptidase, m42
C7M53_05540	COG1301	dicarboxylic acid transport
C7M53_05550	COG1234	tRNA 3'-trailer cleavage
C7M53_05555	COG0095	Lipoate-protein ligase
C7M53_05560	COG0318	PFAM AMP-dependent synthetase and ligase
C7M53_05570	COG1396	sequence-specific DNA binding
C7M53_05585	COG0501	Belongs to the peptidase M48B family
C7M53_05595	COG0697	spore germination
C7M53_05600	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C7M53_05605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M53_05610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M53_05615	COG0406	alpha-ribazole phosphatase activity
C7M53_05620	COG0840	transmembrane signaling receptor activity
C7M53_05625	COG0723	plastoquinol--plastocyanin reductase activity
C7M53_05625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7M53_05630	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_05640	COG4903	ComK protein
C7M53_05650	COG0398	Pfam SNARE associated Golgi protein
C7M53_05655	COG0681	Belongs to the peptidase S26 family
C7M53_05665	COG1404	Belongs to the peptidase S8 family
C7M53_05675	COG2508	Transcriptional regulator
C7M53_05685	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C7M53_05690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M53_05695	COG3257	ureidoglycine aminohydrolase activity
C7M53_05700	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C7M53_05705	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C7M53_05710	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C7M53_05715	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C7M53_05725	COG0549	Belongs to the carbamate kinase family
C7M53_05730	COG2814	Major facilitator Superfamily
C7M53_05740	COG0457	Tetratricopeptide repeat
C7M53_05780	COG1486	melibiose metabolic process
C7M53_05785	COG3180	Ammonia monooxygenase
C7M53_05800	COG3546	catalase activity
C7M53_05805	COG0318	PFAM AMP-dependent synthetase and ligase
C7M53_05810	COG2814	Major facilitator Superfamily
C7M53_05810	COG0477	Major facilitator Superfamily
C7M53_05820	COG5002	protein histidine kinase activity
C7M53_05825	COG0745	RESPONSE REGULATOR receiver
C7M53_05830	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
C7M53_05835	COG0725	ABC transporter, periplasmic molybdate-binding protein
C7M53_05840	COG4149	molybdate abc transporter
C7M53_05845	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
C7M53_05850	COG1074	ATP-dependent DNA helicase activity
C7M53_05855	COG0420	3'-5' exonuclease activity
C7M53_05860	COG0419	ATPase involved in DNA repair
C7M53_05905	COG5337	Spore coat protein CotH
C7M53_05915	COG0179	Fumarylacetoacetate (FAA) hydrolase
C7M53_05940	COG0367	asparagine synthase
C7M53_05945	COG0004	ammonium transporteR
C7M53_05950	COG0347	Belongs to the P(II) protein family
C7M53_05955	COG0534	Mate efflux family protein
C7M53_05960	COG1917	Cupin 2, conserved barrel domain protein
C7M53_05960	COG2207	Transcriptional regulator
C7M53_05970	COG1609	Transcriptional regulator
C7M53_05975	COG0673	inositol 2-dehydrogenase activity
C7M53_05980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M53_05990	COG0076	glutamate decarboxylase activity
C7M53_06015	COG2153	protein acetylation
C7M53_06020	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_06025	COG2378	regulation of single-species biofilm formation
C7M53_06030	COG1410	methionine synthase
C7M53_06030	COG0646	methionine synthase
C7M53_06035	COG0646	methionine synthase
C7M53_06035	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C7M53_06040	COG1666	GTP binding
C7M53_06045	COG2996	Protein conserved in bacteria
C7M53_06060	COG1307	EDD domain protein, DegV family
C7M53_06065	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M53_06075	COG0516	GMP reductase activity
C7M53_06085	COG0561	phosphatase activity
C7M53_06090	COG1073	alpha beta
C7M53_06095	COG2151	metal-sulfur cluster biosynthetic enzyme
C7M53_06105	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C7M53_06110	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C7M53_06115	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C7M53_06120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C7M53_06125	COG0505	Belongs to the CarA family
C7M53_06130	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7M53_06135	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C7M53_06140	COG1968	undecaprenyl-diphosphatase activity
C7M53_06155	COG2267	carboxylic ester hydrolase activity
C7M53_06165	COG1744	ABC transporter substrate-binding protein PnrA-like
C7M53_06180	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7M53_06185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7M53_06190	COG5504	Zn-dependent protease
C7M53_06195	COG0444	Belongs to the ABC transporter superfamily
C7M53_06200	COG4608	Belongs to the ABC transporter superfamily
C7M53_06210	COG0601	transmembrane transport
C7M53_06215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M53_06230	COG0180	Tryptophanyl-tRNA synthetase
C7M53_06240	COG4166	transmembrane transport
C7M53_06245	COG0601	transmembrane transport
C7M53_06250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M53_06260	COG4608	Belongs to the ABC transporter superfamily
C7M53_06265	COG0456	acetyltransferase
C7M53_06270	COG1393	Belongs to the ArsC family
C7M53_06275	COG0861	Integral membrane protein TerC family
C7M53_06280	COG4862	establishment of competence for transformation
C7M53_06300	COG4565	transcriptional regulatory protein
C7M53_06305	COG3290	protein histidine kinase activity
C7M53_06310	COG4469	Competence protein
C7M53_06315	COG1164	Oligoendopeptidase f
C7M53_06325	COG2346	COG2346, Truncated hemoglobins
C7M53_06330	COG0741	lytic transglycosylase activity
C7M53_06335	COG4116	CYTH
C7M53_06345	COG2357	RelA SpoT domain protein
C7M53_06350	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7M53_06355	COG0564	pseudouridine synthase activity
C7M53_06360	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C7M53_06370	COG0569	domain protein
C7M53_06370	COG0475	glutathione-regulated potassium exporter activity
C7M53_06375	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C7M53_06380	COG0352	thiamine-phosphate diphosphorylase activity
C7M53_06390	COG2104	thiamine diphosphate biosynthetic process
C7M53_06395	COG2022	thiamine diphosphate biosynthetic process
C7M53_06400	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7M53_06405	COG0351	phosphomethylpyrimidine kinase
C7M53_06410	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C7M53_06465	COG0210	DNA helicase
C7M53_06475	COG0586	Pfam SNARE associated Golgi protein
C7M53_06480	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7M53_06485	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7M53_06490	COG2246	polysaccharide biosynthetic process
C7M53_06495	COG2153	protein acetylation
C7M53_06500	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C7M53_06505	COG2382	esterase
C7M53_06525	COG0626	cystathionine gamma-synthase activity
C7M53_06530	COG0626	cystathionine gamma-synthase activity
C7M53_06535	COG5505	Protein of unknown function (DUF819)
C7M53_06550	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M53_06555	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M53_06575	COG0110	maltose O-acetyltransferase activity
C7M53_06585	COG0583	DNA-binding transcription factor activity
C7M53_06595	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7M53_06600	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7M53_06605	COG0583	DNA-binding transcription factor activity
C7M53_06610	COG0697	spore germination
C7M53_06615	COG0346	lactoylglutathione lyase activity
C7M53_06625	COG1388	LysM domain
C7M53_06625	COG3584	3D domain protein
C7M53_06630	COG2814	Major facilitator Superfamily
C7M53_06635	COG1309	transcriptional regulator
C7M53_06655	COG5444	nuclease activity
C7M53_06660	COG4195	phage-related replication protein
C7M53_06665	COG2856	Zn peptidase
C7M53_06670	COG1396	sequence-specific DNA binding
C7M53_06685	COG1522	sequence-specific DNA binding
C7M53_06690	COG1484	DNA-dependent DNA replication
C7M53_06705	COG1595	DNA-templated transcription, initiation
C7M53_06710	COG3728	DNA packaging
C7M53_06710	COG5484	DNA packaging
C7M53_06715	COG1783	phage Terminase large subunit
C7M53_06720	COG5518	Phage portal protein
C7M53_06725	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C7M53_06730	COG4653	Phage capsid family
C7M53_06780	COG5412	phage tail tape measure protein
C7M53_06780	COG3953	SLT domain
C7M53_06785	COG1652	LysM domain
C7M53_06790	COG4193	domain, Protein
C7M53_06800	COG3628	GPW Gp25 family protein
C7M53_06805	COG3299	homolog of phage Mu protein gp47
C7M53_06810	COG3778	Protein conserved in bacteria
C7M53_06850	COG1802	Transcriptional regulator
C7M53_06855	COG1063	alcohol dehydrogenase
C7M53_06860	COG1312	Catalyzes the dehydration of D-mannonate
C7M53_06865	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_06870	COG1063	alcohol dehydrogenase
C7M53_06875	COG2271	Major facilitator Superfamily
C7M53_06890	COG0306	phosphate transporter
C7M53_06895	COG1392	Phosphate transport regulator
C7M53_06900	COG0405	Gamma-glutamyltransferase
C7M53_06905	COG5578	integral membrane protein
C7M53_06920	COG2207	Transcriptional regulator
C7M53_06925	COG2755	lipolytic protein G-D-S-L family
C7M53_06935	COG5578	integral membrane protein
C7M53_06940	COG3401	FG-GAP repeat protein
C7M53_06950	COG2755	lipolytic protein G-D-S-L family
C7M53_06955	COG3401	FG-GAP repeat protein
C7M53_06960	COG0667	Aldo Keto reductase
C7M53_06965	COG2755	lipolytic protein G-D-S-L family
C7M53_06970	COG1874	Beta-galactosidase
C7M53_06980	COG1653	transport
C7M53_06985	COG4209	transmembrane transport
C7M53_06990	COG0395	ABC-type sugar transport system, permease component
C7M53_06995	COG0531	amino acid
C7M53_07000	COG0346	lactoylglutathione lyase activity
C7M53_07010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M53_07015	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M53_07020	COG2362	D-Aminopeptidase
C7M53_07025	COG0601	transmembrane transport
C7M53_07030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M53_07035	COG0444	Belongs to the ABC transporter superfamily
C7M53_07040	COG4166	transmembrane transport
C7M53_07045	COG1619	proteins homologs of microcin C7 resistance protein MccF
C7M53_07050	COG4948	Mandelate Racemase Muconate Lactonizing
C7M53_07055	COG0791	NLP P60 protein
C7M53_07060	COG4608	Belongs to the ABC transporter superfamily
C7M53_07065	COG1834	amidinotransferase
C7M53_07070	COG1607	acyl-coa hydrolase
C7M53_07080	COG3866	Pectate lyase
C7M53_07100	COG2318	DinB family
C7M53_07105	COG2076	Multidrug Resistance protein
C7M53_07110	COG2076	Multidrug Resistance protein
C7M53_07115	COG0788	formyltetrahydrofolate deformylase activity
C7M53_07120	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C7M53_07125	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C7M53_07130	COG1764	response to oxidative stress
C7M53_07135	COG1846	Transcriptional regulator
C7M53_07140	COG1764	response to oxidative stress
C7M53_07150	COG0590	tRNA wobble adenosine to inosine editing
C7M53_07155	COG0406	alpha-ribazole phosphatase activity
C7M53_07170	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7M53_07175	COG1404	Belongs to the peptidase S8 family
C7M53_07180	COG2239	Acts as a magnesium transporter
C7M53_07190	COG0582	viral genome integration into host DNA
C7M53_07195	COG2856	Zn peptidase
C7M53_07215	COG3620	sequence-specific DNA binding
C7M53_07255	COG5377	YqaJ viral recombinase family
C7M53_07260	COG3723	Recombinational DNA repair protein, rece pathway
C7M53_07265	COG3935	DnaD domain protein
C7M53_07270	COG1484	DNA-dependent DNA replication
C7M53_07300	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C7M53_07315	COG0629	single-stranded DNA binding
C7M53_07360	COG5484	DNA packaging
C7M53_07365	COG1783	phage Terminase large subunit
C7M53_07490	COG5444	nuclease activity
C7M53_07505	COG0789	Transcriptional regulator
C7M53_07520	COG1846	Transcriptional regulator
C7M53_07525	COG3285	dna ligase
C7M53_07525	COG1793	dna ligase
C7M53_07530	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
C7M53_07535	COG3300	MHYT domain
C7M53_07535	COG5001	Diguanylate cyclase
C7M53_07540	COG0586	Pfam SNARE associated Golgi protein
C7M53_07545	COG0861	Integral membrane protein TerC family
C7M53_07550	COG1191	sigma factor activity
C7M53_07570	COG0501	Belongs to the peptidase M48B family
C7M53_07575	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7M53_07580	COG0768	penicillin binding
C7M53_07595	COG3594	Acyltransferase
C7M53_07600	COG5002	protein histidine kinase activity
C7M53_07605	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7M53_07610	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
C7M53_07615	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
C7M53_07620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7M53_07625	COG0436	Aminotransferase
C7M53_07630	COG1850	ribulose-bisphosphate carboxylase activity
C7M53_07635	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
C7M53_07635	COG0235	Class ii aldolase
C7M53_07640	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
C7M53_07645	COG0346	lactoylglutathione lyase activity
C7M53_07650	COG3339	Conserved Protein
C7M53_07660	COG3852	Histidine kinase
C7M53_07665	COG1846	Transcriptional regulator
C7M53_07670	COG1360	Flagellar Motor Protein
C7M53_07675	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C7M53_07680	COG0542	response to heat
C7M53_07685	COG3949	Membrane
C7M53_07690	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C7M53_07695	COG0720	synthase
C7M53_07700	COG0602	queuosine metabolic process
C7M53_07705	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C7M53_07715	COG4974	Belongs to the 'phage' integrase family
C7M53_07720	COG4974	Belongs to the 'phage' integrase family
C7M53_07775	COG5444	nuclease activity
C7M53_07865	COG0582	viral genome integration into host DNA
C7M53_07995	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M53_07995	COG3409	Peptidoglycan-binding domain 1 protein
C7M53_07995	COG1388	LysM domain
C7M53_08020	COG0582	viral genome integration into host DNA
C7M53_08035	COG3739	integral membrane protein
C7M53_08040	COG3655	Transcriptional regulator
C7M53_08070	COG4873	Protein conserved in bacteria
C7M53_08080	COG3773	Cell wall hydrolase
C7M53_08085	COG2244	polysaccharide biosynthetic process
C7M53_08090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M53_08095	COG2217	Heavy metal translocating P-type atpase
C7M53_08100	COG0006	proline dipeptidase activity
C7M53_08110	COG1609	Transcriptional regulator
C7M53_08115	COG3711	transcriptional antiterminator
C7M53_08120	COG2190	(PTS) system
C7M53_08120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M53_08120	COG1263	PTS System
C7M53_08125	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M53_08130	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7M53_08140	COG1533	DNA photolyase activity
C7M53_08145	COG0456	acetyltransferase
C7M53_08150	COG0840	transmembrane signaling receptor activity
C7M53_08155	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_08160	COG2084	Dehydrogenase
C7M53_08165	COG2340	Cysteine-rich secretory protein family
C7M53_08170	COG0768	penicillin binding
C7M53_08175	COG4191	Histidine kinase
C7M53_08180	COG0436	Aminotransferase
C7M53_08185	COG1714	RDD family
C7M53_08195	COG0784	Response regulator, receiver
C7M53_08195	COG0835	chemotaxis
C7M53_08205	COG2814	Major facilitator Superfamily
C7M53_08210	COG1376	ErfK ybiS ycfS ynhG family protein
C7M53_08220	COG1408	metallophosphoesterase
C7M53_08225	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_08230	COG2200	EAL domain
C7M53_08240	COG4703	Protein of unknown function (DUF1797)
C7M53_08245	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
C7M53_08255	COG0517	IMP dehydrogenase activity
C7M53_08260	COG0583	DNA-binding transcription factor activity
C7M53_08265	COG0716	FMN binding
C7M53_08275	COG0716	FMN binding
C7M53_08280	COG2171	N-acyltransferase activity
C7M53_08285	COG1473	amidohydrolase
C7M53_08295	COG0450	alkyl hydroperoxide reductase
C7M53_08300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M53_08315	COG0746	molybdenum cofactor guanylyltransferase activity
C7M53_08320	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7M53_08325	COG0303	'Molybdopterin
C7M53_08330	COG1763	Mo-molybdopterin cofactor biosynthetic process
C7M53_08335	COG0314	molybdopterin synthase activity
C7M53_08340	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C7M53_08350	COG1132	(ABC) transporter
C7M53_08355	COG1132	(ABC) transporter
C7M53_08365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7M53_08370	COG1136	(ABC) transporter
C7M53_08375	COG0577	efflux transmembrane transporter activity
C7M53_08380	COG1349	DNA-binding transcription factor activity
C7M53_08385	COG1105	Belongs to the carbohydrate kinase PfkB family
C7M53_08390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M53_08390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M53_08390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M53_08410	COG0488	(ABC) transporter
C7M53_08420	COG2309	aminopeptidase activity
C7M53_08430	COG1077	Cell shape determining protein MreB Mrl
C7M53_08435	COG2002	toxin-antitoxin pair type II binding
C7M53_08440	COG3852	Histidine kinase
C7M53_08445	COG0569	domain protein
C7M53_08450	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C7M53_08455	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C7M53_08465	COG0561	phosphatase activity
C7M53_08470	COG0242	peptide deformylase activity
C7M53_08480	COG0497	DNA recombination
C7M53_08485	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7M53_08490	COG0022	dehydrogenase e1 component
C7M53_08495	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M53_08500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M53_08505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M53_08515	COG1982	Orn Lys Arg decarboxylase major
C7M53_08520	COG4476	Belongs to the UPF0223 family
C7M53_08525	COG4493	Belongs to the UPF0637 family
C7M53_08535	COG0483	inositol monophosphate 1-phosphatase activity
C7M53_08555	COG1595	DNA-templated transcription, initiation
C7M53_08580	COG1846	Transcriptional regulator
C7M53_08585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7M53_08590	COG4896	Protein conserved in bacteria
C7M53_08600	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C7M53_08605	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C7M53_08610	COG2066	Belongs to the glutaminase family
C7M53_08615	COG4838	Belongs to the UPF0358 family
C7M53_08620	COG0772	Belongs to the SEDS family
C7M53_08625	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C7M53_08630	COG1612	heme a metabolic process
C7M53_08635	COG0109	protoheme IX farnesyltransferase activity
C7M53_08640	COG2010	Cytochrome c
C7M53_08640	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7M53_08645	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C7M53_08650	COG1845	cytochrome c oxidase, subunit III
C7M53_08655	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C7M53_08660	COG3336	cytochrome c oxidase
C7M53_08670	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
C7M53_08675	COG2340	Cysteine-rich secretory protein family
C7M53_08690	COG3679	Belongs to the UPF0342 family
C7M53_08695	COG4471	UPF0298 protein
C7M53_08700	COG0742	ribosomal rna small subunit methyltransferase
C7M53_08705	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C7M53_08710	COG3314	Sporulation integral membrane protein YlbJ
C7M53_08715	COG3480	Lon protease (S16) C-terminal proteolytic domain
C7M53_08720	COG1323	Belongs to the UPF0348 family
C7M53_08725	COG1399	metal-binding, possibly nucleic acid-binding protein
C7M53_08730	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C7M53_08740	COG0454	-acetyltransferase
C7M53_08745	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C7M53_08750	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
C7M53_08755	COG2001	Belongs to the MraZ family
C7M53_08760	COG0275	rRNA processing
C7M53_08765	COG4839	cell division protein FtsL
C7M53_08775	COG0768	penicillin binding
C7M53_08780	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C7M53_08785	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7M53_08790	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C7M53_08795	COG0772	Belongs to the SEDS family
C7M53_08800	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7M53_08805	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C7M53_08810	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C7M53_08815	COG3879	Bacterial protein of unknown function (DUF881)
C7M53_08820	COG3879	Bacterial protein of unknown function (DUF881)
C7M53_08825	COG3856	small basic protein
C7M53_08830	COG0849	cell division
C7M53_08835	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C7M53_08840	COG4412	M6 family metalloprotease domain protein
C7M53_08840	COG1404	Belongs to the peptidase S8 family
C7M53_08855	COG1191	sigma factor activity
C7M53_08860	COG1191	sigma factor activity
C7M53_08865	COG1119	ATPase activity
C7M53_08870	COG0500	methyltransferase
C7M53_08875	COG1873	PFAM PRC-barrel domain
C7M53_08885	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C7M53_08890	COG1799	cell septum assembly
C7M53_08895	COG0762	integral membrane protein
C7M53_08900	COG2302	S4 RNA-binding domain
C7M53_08905	COG3599	regulation of cell shape
C7M53_08910	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C7M53_08915	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7M53_08920	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C7M53_08925	COG0564	pseudouridine synthase activity
C7M53_08930	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
C7M53_08935	COG2233	PERMEase
C7M53_08940	COG0540	Belongs to the ATCase OTCase family
C7M53_08945	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C7M53_08950	COG0505	Belongs to the CarA family
C7M53_08955	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7M53_08960	COG0543	2 iron, 2 sulfur cluster binding
C7M53_08965	COG0167	dihydroorotate dehydrogenase activity
C7M53_08970	COG0284	orotidine-5'-phosphate decarboxylase activity
C7M53_08975	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C7M53_08985	COG0175	sulfate reduction
C7M53_08990	COG0306	phosphate transporter
C7M53_08995	COG2046	Belongs to the sulfate adenylyltransferase family
C7M53_09000	COG0529	Catalyzes the synthesis of activated sulfate
C7M53_09005	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C7M53_09010	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
C7M53_09015	COG1648	precorrin-2 dehydrogenase activity
C7M53_09025	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7M53_09030	COG1561	YicC-like family, N-terminal region
C7M53_09035	COG2052	Domain of unknown function (DUF370)
C7M53_09040	COG0194	GDP metabolic process
C7M53_09045	COG1758	RNA polymerase activity
C7M53_09050	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7M53_09055	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7M53_09060	COG0242	peptide deformylase activity
C7M53_09065	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C7M53_09070	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C7M53_09070	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7M53_09075	COG0820	rRNA (adenine-C2-)-methyltransferase activity
C7M53_09080	COG0631	protein serine/threonine phosphatase activity
C7M53_09085	COG2815	serine threonine protein kinase
C7M53_09085	COG0515	serine threonine protein kinase
C7M53_09090	COG1162	GTPase activity
C7M53_09095	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7M53_09100	COG1564	THIamine pyrophosphokinase
C7M53_09110	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C7M53_09115	COG1302	Protein conserved in bacteria
C7M53_09120	COG1461	Dihydroxyacetone kinase
C7M53_09125	COG1760	l-serine dehydratase
C7M53_09130	COG1760	l-serine dehydratase
C7M53_09135	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C7M53_09140	COG1349	DNA-binding transcription factor activity
C7M53_09145	COG0416	fatty acid biosynthetic process
C7M53_09150	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7M53_09155	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_09160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M53_09165	COG0571	ribonuclease III activity
C7M53_09170	COG1196	nuclear chromosome segregation
C7M53_09175	COG0552	protein localization to endoplasmic reticulum
C7M53_09180	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
C7M53_09185	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C7M53_09190	COG0228	four-way junction DNA binding
C7M53_09195	COG1837	Belongs to the UPF0109 family
C7M53_09205	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C7M53_09210	COG0336	Belongs to the RNA methyltransferase TrmD family
C7M53_09215	COG0335	large ribosomal subunit rRNA binding
C7M53_09220	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7M53_09225	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7M53_09235	COG2257	FlhB HrpN YscU SpaS Family
C7M53_09240	COG0045	succinate-CoA ligase (ADP-forming) activity
C7M53_09245	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C7M53_09250	COG0758	DNA mediated transformation
C7M53_09255	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7M53_09260	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
C7M53_09265	COG4974	Belongs to the 'phage' integrase family
C7M53_09270	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
C7M53_09275	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C7M53_09280	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C7M53_09285	COG1815	bacterial-type flagellum-dependent cell motility
C7M53_09290	COG1558	bacterial-type flagellum-dependent cell motility
C7M53_09295	COG1677	Flagellar hook-basal body complex protein FliE
C7M53_09300	COG1766	The M ring may be actively involved in energy transduction
C7M53_09305	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7M53_09310	COG1317	bacterial-type flagellum organization
C7M53_09315	COG1157	protein secretion by the type III secretion system
C7M53_09320	COG2882	bacterial-type flagellum organization
C7M53_09330	COG3144	bacterial-type flagellum assembly
C7M53_09335	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C7M53_09340	COG4786	Flagellar basal body rod
C7M53_09345	COG1582	Flagellar protein (FlbD)
C7M53_09350	COG1580	Controls the rotational direction of flagella during chemotaxis
C7M53_09355	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7M53_09360	COG1776	CheC inhibitor of MCP methylation
C7M53_09360	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7M53_09365	COG2201	protein-glutamate methylesterase activity
C7M53_09370	COG3190	flagellar
C7M53_09375	COG1338	Plays a role in the flagellum-specific transport system
C7M53_09380	COG1987	bacterial-type flagellum assembly
C7M53_09385	COG1684	flagellar biosynthetic protein fliR
C7M53_09390	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C7M53_09395	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C7M53_09400	COG1419	protein localization to endoplasmic reticulum
C7M53_09405	COG0455	bacterial-type flagellum organization
C7M53_09410	COG2201	protein-glutamate methylesterase activity
C7M53_09415	COG2198	Histidine kinase
C7M53_09415	COG0643	Histidine kinase
C7M53_09420	COG0835	chemotaxis
C7M53_09425	COG1776	CheC inhibitor of MCP methylation
C7M53_09430	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
C7M53_09435	COG1191	sigma factor activity
C7M53_09445	COG0052	Belongs to the universal ribosomal protein uS2 family
C7M53_09450	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C7M53_09455	COG0528	UMP kinase activity
C7M53_09460	COG0233	cytoplasmic translational termination
C7M53_09465	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C7M53_09470	COG4589	Belongs to the CDS family
C7M53_09475	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C7M53_09480	COG0750	zinc metalloprotease
C7M53_09485	COG0442	prolyl-tRNA aminoacylation
C7M53_09490	COG2176	DNA-directed DNA polymerase activity
C7M53_09520	COG0779	Required for maturation of 30S ribosomal subunits
C7M53_09525	COG0195	Participates in both transcription termination and antitermination
C7M53_09530	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C7M53_09535	COG1358	cellular component organization or biogenesis
C7M53_09540	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C7M53_09545	COG1550	Protein conserved in bacteria
C7M53_09550	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C7M53_09555	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C7M53_09560	COG0196	riboflavin kinase activity
C7M53_09565	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C7M53_09570	COG1185	polyribonucleotide nucleotidyltransferase activity
C7M53_09575	COG0726	polysaccharide deacetylase
C7M53_09580	COG0612	Peptidase, M16
C7M53_09585	COG1873	PFAM PRC-barrel domain
C7M53_09590	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7M53_09595	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7M53_09600	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C7M53_09605	COG0527	aspartate kinase activity
C7M53_09615	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C7M53_09620	COG0740	serine-type endopeptidase activity
C7M53_09630	COG1674	ftsk spoiiie
C7M53_09630	COG4980	gas vesicle protein
C7M53_09635	COG2188	Transcriptional regulator
C7M53_09640	COG2814	Major facilitator Superfamily
C7M53_09645	COG0612	Peptidase, M16
C7M53_09650	COG0612	Peptidase, M16
C7M53_09655	COG0300	oxidoreductase activity
C7M53_09670	COG1426	Protein conserved in bacteria
C7M53_09675	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C7M53_09680	COG1058	Belongs to the CinA family
C7M53_09680	COG1546	Belongs to the CinA family
C7M53_09685	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C7M53_09690	COG1418	mRNA catabolic process
C7M53_09695	COG1692	metallophosphoesterase
C7M53_09700	COG2359	stage V sporulation protein S
C7M53_09710	COG1063	alcohol dehydrogenase
C7M53_09715	COG0156	8-amino-7-oxononanoate synthase activity
C7M53_09720	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7M53_09725	COG4550	Control of competence regulator ComK, YlbF/YmcA
C7M53_09735	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C7M53_09740	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C7M53_09745	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C7M53_09750	COG5444	nuclease activity
C7M53_09770	COG0523	cobalamin synthesis protein
C7M53_09780	COG1247	-acetyltransferase
C7M53_09800	COG3619	membrane
C7M53_09805	COG3263	regulation of cellular component size
C7M53_09815	COG2267	carboxylic ester hydrolase activity
C7M53_09820	COG2267	carboxylic ester hydrolase activity
C7M53_09830	COG0393	Putative heavy-metal-binding
C7M53_09835	COG0398	Pfam SNARE associated Golgi protein
C7M53_09840	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M53_09845	COG1819	glycosyl
C7M53_09850	COG0531	amino acid
C7M53_09855	COG5577	PFAM Coat F domain
C7M53_09865	COG3858	chitin binding
C7M53_09865	COG1388	LysM domain
C7M53_09870	COG1309	transcriptional regulator
C7M53_09875	COG3631	Ketosteroid isomerase-related protein
C7M53_09880	COG0702	epimerase
C7M53_09890	COG1764	response to oxidative stress
C7M53_09895	COG2076	Multidrug Resistance protein
C7M53_09900	COG2076	Multidrug Resistance protein
C7M53_09915	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C7M53_09920	COG1923	regulation of RNA biosynthetic process
C7M53_09935	COG1780	Probably involved in ribonucleotide reductase function
C7M53_09940	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M53_09945	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M53_09950	COG4112	unkown
C7M53_09965	COG0735	belongs to the Fur family
C7M53_09970	COG1802	Transcriptional regulator
C7M53_09975	COG0697	spore germination
C7M53_10010	COG1309	transcriptional regulator
C7M53_10060	COG0464	growth
C7M53_10065	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C7M53_10070	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
C7M53_10075	COG0789	Transcriptional regulator
C7M53_10080	COG0174	glutamine synthetase
C7M53_10120	COG1073	alpha beta
C7M53_10160	COG1309	transcriptional regulator
C7M53_10165	COG2076	Multidrug Resistance protein
C7M53_10170	COG2076	Multidrug Resistance protein
C7M53_10175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M53_10195	COG3546	catalase activity
C7M53_10220	COG1846	Transcriptional regulator
C7M53_10225	COG0778	Nitroreductase
C7M53_10230	COG0346	lactoylglutathione lyase activity
C7M53_10235	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7M53_10240	COG0655	NAD(P)H dehydrogenase (quinone) activity
C7M53_10255	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C7M53_10260	COG3209	COG3209 Rhs family protein
C7M53_10265	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C7M53_10270	COG1388	LysM domain
C7M53_10275	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C7M53_10280	COG4224	UPF0291 protein
C7M53_10285	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C7M53_10295	COG3763	UPF0154 protein
C7M53_10305	COG0785	Cytochrome C biogenesis protein
C7M53_10310	COG2201	protein-glutamate methylesterase activity
C7M53_10315	COG4846	Membrane protein involved in cytochrome C biogenesis
C7M53_10325	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M53_10340	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C7M53_10345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M53_10365	COG0824	Thioesterase
C7M53_10390	COG4841	protein insertion into membrane
C7M53_10395	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C7M53_10400	COG1832	CoA-binding protein
C7M53_10405	COG0187	DNA topoisomerase II activity
C7M53_10410	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7M53_10415	COG1609	Transcriptional regulator
C7M53_10430	COG2160	L-arabinose isomerase activity
C7M53_10450	COG1115	amino acid carrier protein
C7M53_10460	COG2181	nitrate reductase activity
C7M53_10465	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C7M53_10470	COG1140	nitrate reductase beta subunit
C7M53_10475	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C7M53_10495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7M53_10505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7M53_10510	COG2223	nitrite transmembrane transporter activity
C7M53_10530	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
C7M53_10540	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
C7M53_10550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M53_10560	COG0492	ferredoxin-NADP+ reductase activity
C7M53_10575	COG3420	alginic acid biosynthetic process
C7M53_10580	COG1114	Component of the transport system for branched-chain amino acids
C7M53_10585	COG1064	alcohol dehydrogenase
C7M53_10590	COG0789	Transcriptional regulator
C7M53_10620	COG1024	Enoyl-CoA hydratase
C7M53_10625	COG1012	belongs to the aldehyde dehydrogenase family
C7M53_10630	COG2084	Dehydrogenase
C7M53_10635	COG1960	acyl-CoA dehydrogenase activity
C7M53_10640	COG1482	cell wall glycoprotein biosynthetic process
C7M53_10645	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M53_10645	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M53_10645	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M53_10670	COG3711	transcriptional antiterminator
C7M53_10670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M53_10685	COG1725	Transcriptional regulator
C7M53_10690	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_10695	COG1312	Catalyzes the dehydration of D-mannonate
C7M53_10710	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C7M53_10720	COG1609	Transcriptional regulator
C7M53_10725	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7M53_10730	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C7M53_10735	COG0640	Transcriptional regulator
C7M53_10745	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
C7M53_10760	COG1649	PFAM Uncharacterised BCR, COG1649
C7M53_10765	COG2404	hydrolase activity, acting on ester bonds
C7M53_10770	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C7M53_10780	COG2027	D-alanyl-D-alanine carboxypeptidase
C7M53_10785	COG1252	NADH dehydrogenase
C7M53_10800	COG0166	Belongs to the GPI family
C7M53_10810	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7M53_10815	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C7M53_10820	COG1024	Enoyl-CoA hydratase
C7M53_10825	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C7M53_10830	COG0511	ligase activity, forming carbon-carbon bonds
C7M53_10835	COG0439	Biotin carboxylase
C7M53_10840	COG0318	PFAM AMP-dependent synthetase and ligase
C7M53_10845	COG1960	acyl-CoA dehydrogenase activity
C7M53_10850	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7M53_10855	COG1733	regulation of RNA biosynthetic process
C7M53_10860	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C7M53_10865	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C7M53_10875	COG2323	membrane
C7M53_10885	COG0306	phosphate transporter
C7M53_10890	COG0175	sulfate reduction
C7M53_10895	COG1809	phosphosulfolactate synthase activity
C7M53_10900	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M53_10910	COG2814	Major facilitator Superfamily
C7M53_10915	COG0463	Glycosyl transferase, family 2
C7M53_10930	COG0493	'glutamate synthase
C7M53_10935	COG0067	glutamate synthase
C7M53_10935	COG0069	glutamate synthase activity
C7M53_10935	COG0070	glutamate synthase
C7M53_10940	COG0583	DNA-binding transcription factor activity
C7M53_10960	COG1846	Transcriptional regulator
C7M53_10970	COG1132	(ABC) transporter
C7M53_10980	COG0300	oxidoreductase activity
C7M53_10985	COG0574	Belongs to the PEP-utilizing enzyme family
C7M53_10985	COG3848	Pyruvate phosphate dikinase
C7M53_10995	COG0477	Major facilitator Superfamily
C7M53_11000	COG0243	molybdopterin cofactor binding
C7M53_11005	COG1846	Transcriptional regulator
C7M53_11015	COG0531	amino acid
C7M53_11025	COG0531	amino acid
C7M53_11030	COG0531	amino acid
C7M53_11035	COG0697	spore germination
C7M53_11045	COG0840	transmembrane signaling receptor activity
C7M53_11050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M53_11055	COG1404	Belongs to the peptidase S8 family
C7M53_11065	COG1309	transcriptional regulator
C7M53_11070	COG1846	Transcriptional regulator
C7M53_11100	COG1309	transcriptional regulator
C7M53_11105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M53_11110	COG3708	Transcriptional regulator
C7M53_11120	COG2378	regulation of single-species biofilm formation
C7M53_11130	COG0640	Transcriptional regulator
C7M53_11135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M53_11145	COG0531	amino acid
C7M53_11150	COG0741	lytic transglycosylase activity
C7M53_11155	COG1086	Polysaccharide biosynthesis protein
C7M53_11175	COG2322	membrane
C7M53_11190	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M53_11195	COG1388	LysM domain
C7M53_11195	COG3584	3D domain protein
C7M53_11200	COG0514	ATP-dependent DNA helicase (RecQ)
C7M53_11220	COG2315	Protein conserved in bacteria
C7M53_11240	COG2427	Protein of unknown function (DUF1641)
C7M53_11245	COG3383	formate dehydrogenase (NAD+) activity
C7M53_11265	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
C7M53_11315	COG0402	S-adenosylhomocysteine deaminase activity
C7M53_11330	COG2267	carboxylic ester hydrolase activity
C7M53_11345	COG1280	lysine exporter protein (LysE YggA)
C7M53_11350	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C7M53_11360	COG0574	Belongs to the PEP-utilizing enzyme family
C7M53_11360	COG3848	Pyruvate phosphate dikinase
C7M53_11365	COG1309	transcriptional regulator
C7M53_11380	COG2318	DinB family
C7M53_11385	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C7M53_11390	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7M53_11405	COG1012	belongs to the aldehyde dehydrogenase family
C7M53_11410	COG2814	Major facilitator Superfamily
C7M53_11425	COG1657	PFAM Prenyltransferase squalene oxidase
C7M53_11430	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C7M53_11440	COG0733	neurotransmitter:sodium symporter activity
C7M53_11445	COG0385	Bile acid
C7M53_11450	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M53_11455	COG0567	Dehydrogenase, E1 component
C7M53_11460	COG4548	von Willebrand factor, type A
C7M53_11465	COG0714	Associated with various cellular activities
C7M53_11470	COG2032	superoxide dismutase activity
C7M53_11475	COG0791	NLP P60 protein
C7M53_11475	COG1388	LysM domain
C7M53_11485	COG0534	Mate efflux family protein
C7M53_11490	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7M53_11495	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7M53_11505	COG2962	Rard protein
C7M53_11515	COG4305	rare lipoprotein A
C7M53_11525	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_11530	COG1733	regulation of RNA biosynthetic process
C7M53_11535	COG0778	Nitroreductase
C7M53_11540	COG0400	carboxylic ester hydrolase activity
C7M53_11550	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M53_11555	COG3409	Peptidoglycan-binding domain 1 protein
C7M53_11555	COG0793	Belongs to the peptidase S41A family
C7M53_11560	COG2226	methyltransferase
C7M53_11570	COG1876	peptidase activity
C7M53_11575	COG0813	purine-nucleoside phosphorylase activity
C7M53_11580	COG0701	Predicted permease
C7M53_11600	COG0671	phosphoesterase, PA-phosphatase related
C7M53_11615	COG4479	Belongs to the UPF0346 family
C7M53_11635	COG3331	DNA recombination
C7M53_11645	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
C7M53_11710	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C7M53_11730	COG0756	dUTP diphosphatase activity
C7M53_11750	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M53_11760	COG1372	Participates in initiation and elongation during chromosome replication
C7M53_11760	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M53_11765	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M53_11770	COG1780	Probably involved in ribonucleotide reductase function
C7M53_11830	COG3584	3D domain protein
C7M53_11835	COG0587	DNA-directed DNA polymerase activity
C7M53_11845	COG0587	DNA-directed DNA polymerase activity
C7M53_11850	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C7M53_11855	COG0358	DNA primase activity
C7M53_11860	COG0305	Participates in initiation and elongation during chromosome replication
C7M53_11870	COG2887	Belongs to the helicase family. UvrD subfamily
C7M53_11925	COG1793	dna ligase
C7M53_11980	COG4474	Belongs to the UPF0398 family
C7M53_11990	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7M53_12025	COG0582	viral genome integration into host DNA
C7M53_12055	COG1404	Belongs to the peptidase S8 family
C7M53_12110	COG3655	Transcriptional regulator
C7M53_12175	COG1404	Belongs to the peptidase S8 family
C7M53_12205	COG0776	regulation of translation
C7M53_12240	COG4373	Mu-like prophage FluMu protein gp28
C7M53_12335	COG0582	viral genome integration into host DNA
C7M53_12360	COG3226	Transcriptional regulator
C7M53_12420	COG1196	nuclear chromosome segregation
C7M53_12420	COG0741	lytic transglycosylase activity
C7M53_12420	COG0739	heme binding
C7M53_12425	COG0739	heme binding
C7M53_12425	COG0741	lytic transglycosylase activity
C7M53_12425	COG1196	nuclear chromosome segregation
C7M53_12435	COG2433	Pfam Transposase IS66
C7M53_12445	COG5434	Belongs to the glycosyl hydrolase 28 family
C7M53_12450	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M53_12475	COG0457	Tetratricopeptide repeat
C7M53_12480	COG2814	Major facilitator Superfamily
C7M53_12520	COG5444	nuclease activity
C7M53_12525	COG4282	regulation of fungal-type cell wall biogenesis
C7M53_12535	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C7M53_12540	COG1509	lysine 2,3-aminomutase activity
C7M53_12545	COG0456	acetyltransferase
C7M53_12550	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M53_12555	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C7M53_12560	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C7M53_12565	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7M53_12580	COG0456	acetyltransferase
C7M53_12585	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7M53_12590	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7M53_12595	COG1846	Transcriptional regulator
C7M53_12605	COG3706	GGDEF domain
C7M53_12610	COG0534	Mate efflux family protein
C7M53_12625	COG4698	Protein conserved in bacteria
C7M53_12630	COG2755	lipolytic protein G-D-S-L family
C7M53_12635	COG1999	signal sequence binding
C7M53_12650	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C7M53_12655	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C7M53_12660	COG1272	protein, Hemolysin III
C7M53_12665	COG0204	Acyl-transferase
C7M53_12670	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7M53_12675	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C7M53_12685	COG2521	methyltransferase
C7M53_12685	COG2136	Putative SAM-dependent methyltransferase
C7M53_12695	COG0129	dihydroxy-acid dehydratase activity
C7M53_12700	COG1413	lyase activity
C7M53_12705	COG1418	mRNA catabolic process
C7M53_12710	COG0386	Belongs to the glutathione peroxidase family
C7M53_12715	COG2759	Belongs to the formate--tetrahydrofolate ligase family
C7M53_12720	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
C7M53_12725	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7M53_12735	COG1278	Cold shock
C7M53_12755	COG0328	RNA-DNA hybrid ribonuclease activity
C7M53_12760	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C7M53_12765	COG0328	RNA-DNA hybrid ribonuclease activity
C7M53_12775	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M53_12785	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C7M53_12795	COG1755	Isoprenylcysteine carboxyl methyltransferase
C7M53_12800	COG3424	synthase
C7M53_12805	COG0456	acetyltransferase
C7M53_12810	COG2233	PERMEase
C7M53_12815	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7M53_12820	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C7M53_12825	COG1199	ATP-dependent helicase activity
C7M53_12835	COG0116	Belongs to the methyltransferase superfamily
C7M53_12845	COG3599	regulation of cell shape
C7M53_12850	COG4474	Belongs to the UPF0398 family
C7M53_12860	COG3359	exonuclease
C7M53_12865	COG1111	helicase
C7M53_12865	COG1205	dead DEAH box helicase
C7M53_12870	COG2190	(PTS) system
C7M53_12875	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M53_12910	COG3331	DNA recombination
C7M53_12915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M53_12915	COG4499	WXG100 protein secretion system (Wss), protein YukC
C7M53_12925	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C7M53_12930	COG3935	DnaD domain protein
C7M53_12935	COG0017	Asparaginyl-tRNA synthetase
C7M53_12940	COG0436	Aminotransferase
C7M53_12945	COG5353	protein conserved in bacteria
C7M53_12955	COG1199	ATP-dependent helicase activity
C7M53_12955	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7M53_12960	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
C7M53_12965	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
C7M53_12970	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
C7M53_12985	COG0617	tRNA 3'-terminal CCA addition
C7M53_12990	COG0438	transferase activity, transferring glycosyl groups
C7M53_12995	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7M53_13000	COG1803	Methylglyoxal synthase
C7M53_13005	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C7M53_13010	COG1694	Mazg nucleotide pyrophosphohydrolase
C7M53_13015	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M53_13025	COG4347	Protein of unknown function (DUF1405)
C7M53_13030	COG2010	Cytochrome c
C7M53_13030	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C7M53_13035	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C7M53_13040	COG0723	plastoquinol--plastocyanin reductase activity
C7M53_13050	COG5582	Belongs to the UPF0302 family
C7M53_13055	COG0457	Tetratricopeptide repeat
C7M53_13060	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C7M53_13065	COG0287	Prephenate dehydrogenase
C7M53_13070	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C7M53_13075	COG0159	tryptophan synthase activity
C7M53_13080	COG0133	tryptophan synthase activity
C7M53_13085	COG0135	phosphoribosylanthranilate isomerase activity
C7M53_13090	COG0134	indole-3-glycerol-phosphate synthase activity
C7M53_13095	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C7M53_13100	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7M53_13105	COG4401	Chorismate mutase type I
C7M53_13110	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C7M53_13115	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C7M53_13120	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C7M53_13125	COG0105	UTP biosynthetic process
C7M53_13130	COG0142	geranyltranstransferase activity
C7M53_13135	COG2226	methyltransferase
C7M53_13140	COG0142	geranyltranstransferase activity
C7M53_13155	COG0776	regulation of translation
C7M53_13160	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C7M53_13180	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C7M53_13185	COG1160	GTP binding
C7M53_13210	COG1304	FMN binding
C7M53_13215	COG0539	negative regulation of cytoplasmic translation
C7M53_13220	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C7M53_13225	COG2959	enzyme of heme biosynthesis
C7M53_13230	COG3409	Peptidoglycan-binding domain 1 protein
C7M53_13230	COG3773	Cell wall hydrolase
C7M53_13235	COG2339	peptidase activity
C7M53_13245	COG0492	ferredoxin-NADP+ reductase activity
C7M53_13250	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7M53_13255	COG4862	establishment of competence for transformation
C7M53_13260	COG1408	metallophosphoesterase
C7M53_13270	COG1388	LysM domain
C7M53_13275	COG1266	CAAX protease self-immunity
C7M53_13280	COG0514	ATP-dependent DNA helicase (RecQ)
C7M53_13285	COG4955	Helix-turn-helix domain
C7M53_13290	COG1141	Ferredoxin
C7M53_13295	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C7M53_13300	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7M53_13305	COG0739	heme binding
C7M53_13315	COG1595	DNA-templated transcription, initiation
C7M53_13335	COG5002	protein histidine kinase activity
C7M53_13345	COG5002	protein histidine kinase activity
C7M53_13350	COG0745	RESPONSE REGULATOR receiver
C7M53_13355	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7M53_13360	COG1333	cytochrome c biogenesis protein
C7M53_13365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M53_13370	COG1187	pseudouridine synthase activity
C7M53_13375	COG0700	Nucleoside recognition
C7M53_13380	COG2715	membrane protein required for spore maturation
C7M53_13385	COG1686	Belongs to the peptidase S11 family
C7M53_13395	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C7M53_13400	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C7M53_13410	COG1547	Domain of unknown function (DUF309)
C7M53_13415	COG0456	acetyltransferase
C7M53_13420	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C7M53_13425	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7M53_13425	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7M53_13430	COG0307	riboflavin synthase, alpha
C7M53_13435	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7M53_13435	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7M53_13460	COG0457	Tetratricopeptide repeat
C7M53_13465	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C7M53_13470	COG4086	secreted protein
C7M53_13475	COG4195	phage-related replication protein
C7M53_13480	COG0019	diaminopimelate decarboxylase activity
C7M53_13490	COG0697	spore germination
C7M53_13505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7M53_13530	COG2172	sigma factor antagonist activity
C7M53_13540	COG1686	Belongs to the peptidase S11 family
C7M53_13545	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C7M53_13550	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C7M53_13555	COG4974	Belongs to the 'phage' integrase family
C7M53_13565	COG0735	belongs to the Fur family
C7M53_13570	COG1300	Membrane
C7M53_13575	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M53_13595	COG2153	protein acetylation
C7M53_13600	COG1379	DNA repair
C7M53_13605	COG0494	nUDIX hydrolase
C7M53_13615	COG1309	transcriptional regulator
C7M53_13625	COG0667	Aldo Keto reductase
C7M53_13635	COG1073	alpha beta
C7M53_13645	COG4918	Iron-sulphur cluster biosynthesis
C7M53_13655	COG0456	acetyltransferase
C7M53_13655	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C7M53_13660	COG2329	Antibiotic biosynthesis monooxygenase
C7M53_13670	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C7M53_13680	COG0747	negative chemotaxis
C7M53_13685	COG0601	transmembrane transport
C7M53_13690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M53_13695	COG0444	Belongs to the ABC transporter superfamily
C7M53_13700	COG0534	Mate efflux family protein
C7M53_13715	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7M53_13725	COG2211	Major facilitator Superfamily
C7M53_13730	COG0346	lactoylglutathione lyase activity
C7M53_13735	COG1072	(Pantothenic acid kinase))
C7M53_13770	COG4195	phage-related replication protein
C7M53_13780	COG0300	oxidoreductase activity
C7M53_13785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M53_13790	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M53_13795	COG4187	Peptidase family M20/M25/M40
C7M53_13800	COG1902	pentaerythritol trinitrate reductase activity
C7M53_13805	COG0596	Alpha beta hydrolase
C7M53_13810	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7M53_13815	COG1234	tRNA 3'-trailer cleavage
C7M53_13820	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C7M53_13840	COG2188	Transcriptional regulator
C7M53_13845	COG2723	6-phospho-beta-galactosidase activity
C7M53_13850	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M53_13855	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7M53_13860	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M53_13865	COG1785	Belongs to the alkaline phosphatase family
C7M53_13870	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_13875	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C7M53_13880	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7M53_13890	COG0706	membrane insertase activity
C7M53_13895	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7M53_13900	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C7M53_13905	COG4129	membrane
C7M53_13910	COG1126	abc transporter atp-binding protein
C7M53_13915	COG0765	amino acid transport
C7M53_13920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M53_13930	COG1597	lipid kinase activity
C7M53_13935	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M53_13940	COG0022	dehydrogenase e1 component
C7M53_13945	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7M53_13950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M53_13955	COG3426	butyrate kinase activity
C7M53_13965	COG0280	phosphate acetyltransferase
C7M53_13970	COG3829	transcription factor binding
C7M53_13970	COG3290	protein histidine kinase activity
C7M53_13980	COG0584	glycerophosphoryl diester phosphodiesterase
C7M53_13985	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M53_14000	COG1045	serine acetyltransferase
C7M53_14010	COG0745	RESPONSE REGULATOR receiver
C7M53_14015	COG0750	zinc metalloprotease
C7M53_14020	COG0497	DNA recombination
C7M53_14025	COG1438	arginine binding
C7M53_14030	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C7M53_14035	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C7M53_14040	COG0142	geranyltranstransferase activity
C7M53_14045	COG1722	exodeoxyribonuclease VII activity
C7M53_14050	COG1570	exodeoxyribonuclease VII activity
C7M53_14055	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C7M53_14060	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7M53_14065	COG1302	Protein conserved in bacteria
C7M53_14070	COG0439	Biotin carboxylase
C7M53_14075	COG0511	ligase activity, forming carbon-carbon bonds
C7M53_14115	COG3854	ATPases associated with a variety of cellular activities
C7M53_14125	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C7M53_14130	COG0006	proline dipeptidase activity
C7M53_14135	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C7M53_14145	COG3872	metal-dependent enzyme
C7M53_14155	COG1752	Esterase of the alpha-beta hydrolase superfamily
C7M53_14160	COG1321	iron dependent repressor
C7M53_14165	COG0095	Lipoate-protein ligase
C7M53_14170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M53_14175	COG2113	Glycine betaine
C7M53_14180	COG4176	ABC-type proline glycine betaine transport system permease component
C7M53_14185	COG0517	IMP dehydrogenase activity
C7M53_14185	COG4175	Glycine betaine
C7M53_14190	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C7M53_14195	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C7M53_14200	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C7M53_14205	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C7M53_14230	COG0681	Belongs to the peptidase S26 family
C7M53_14255	COG4940	Competence protein ComGF
C7M53_14265	COG4970	Tfp pilus assembly protein FimT
C7M53_14270	COG4537	Required for transformation and DNA binding
C7M53_14275	COG1459	type II secretion system
C7M53_14280	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C7M53_14285	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M53_14295	COG1393	Belongs to the ArsC family
C7M53_14305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M53_14315	COG0011	TIGRFAM Protein of
C7M53_14325	COG2866	Carboxypeptidase
C7M53_14330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M53_14335	COG1368	sulfuric ester hydrolase activity
C7M53_14340	COG1940	carbohydrate kinase activity
C7M53_14345	COG4483	Protein conserved in bacteria
C7M53_14350	COG0697	spore germination
C7M53_14355	COG0705	Rhomboid family
C7M53_14355	COG0457	Tetratricopeptide repeat
C7M53_14360	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C7M53_14365	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7M53_14370	COG0438	transferase activity, transferring glycosyl groups
C7M53_14385	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C7M53_14390	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7M53_14395	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7M53_14400	COG0581	inorganic phosphate transmembrane transporter activity
C7M53_14405	COG0573	inorganic phosphate transmembrane transporter activity
C7M53_14410	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7M53_14420	COG0477	Major facilitator Superfamily
C7M53_14425	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C7M53_14430	COG2839	Protein conserved in bacteria
C7M53_14435	COG5521	maltodextrose utilization protein MalA
C7M53_14440	COG1388	LysM domain
C7M53_14445	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C7M53_14450	COG4709	membrane
C7M53_14455	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
C7M53_14460	COG0735	belongs to the Fur family
C7M53_14465	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7M53_14470	COG1121	(ABC) transporter
C7M53_14475	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M53_14485	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
C7M53_14490	COG0513	Belongs to the DEAD box helicase family
C7M53_14500	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C7M53_14505	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C7M53_14510	COG2384	SAM-dependent methyltransferase
C7M53_14560	COG5444	nuclease activity
C7M53_14575	COG2010	Cytochrome c
C7M53_14580	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7M53_14585	COG0358	DNA primase activity
C7M53_14590	COG1671	Belongs to the UPF0178 family
C7M53_14595	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C7M53_14600	COG0517	IMP dehydrogenase activity
C7M53_14605	COG0751	glycine-tRNA ligase activity
C7M53_14610	COG0752	glycyl-tRNA synthetase alpha subunit
C7M53_14615	COG1381	Involved in DNA repair and RecF pathway recombination
C7M53_14625	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C7M53_14630	COG0295	cytidine deaminase activity
C7M53_14635	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C7M53_14640	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C7M53_14645	COG1480	7TM receptor with intracellular HD hydrolase
C7M53_14650	COG1702	phosphate starvation-inducible protein PhoH
C7M53_14655	COG0561	phosphatase activity
C7M53_14670	COG4864	UPF0365 protein
C7M53_14675	COG1030	water channel activity
C7M53_14680	COG1610	YqeY-like protein
C7M53_14685	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C7M53_14690	COG1283	sodium-dependent phosphate transmembrane transporter activity
C7M53_14695	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C7M53_14700	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7M53_14705	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C7M53_14710	COG2264	protein methyltransferase activity
C7M53_14715	COG0484	heat shock protein binding
C7M53_14720	COG0443	Heat shock 70 kDa protein
C7M53_14725	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C7M53_14730	COG1420	regulation of RNA biosynthetic process
C7M53_14735	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7M53_14740	COG0481	GTPase activity
C7M53_14755	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C7M53_14760	COG0268	Binds directly to 16S ribosomal RNA
C7M53_14765	COG1466	dna polymerase III delta subunit
C7M53_14775	COG2333	competence protein COMEC
C7M53_14775	COG0658	competence protein
C7M53_14780	COG2131	deaminase
C7M53_14785	COG1596	polysaccharide export
C7M53_14785	COG1555	photosystem II stabilization
C7M53_14790	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M53_14795	COG2226	methyltransferase
C7M53_14800	COG0799	negative regulation of ribosome biogenesis
C7M53_14805	COG1713	HD superfamily hydrolase involved in NAD metabolism
C7M53_14810	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C7M53_14815	COG1534	Rna-binding protein
C7M53_14820	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C7M53_14825	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7M53_14830	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C7M53_14840	COG2755	lipolytic protein G-D-S-L family
C7M53_14845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M53_14850	COG5609	conserved protein (DUF2294)
C7M53_14855	COG3383	formate dehydrogenase (NAD+) activity
C7M53_14860	COG2427	Protein of unknown function (DUF1641)
C7M53_14900	COG0300	oxidoreductase activity
C7M53_14905	COG1902	pentaerythritol trinitrate reductase activity
C7M53_14910	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M53_14910	COG0596	Alpha beta hydrolase
C7M53_14915	COG1309	transcriptional regulator
C7M53_14925	COG1063	alcohol dehydrogenase
C7M53_14960	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M53_15025	COG2197	response regulator
C7M53_15030	COG4585	Histidine kinase
C7M53_15035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M53_15040	COG0730	response to heat
C7M53_15045	COG0425	Belongs to the sulfur carrier protein TusA family
C7M53_15050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M53_15050	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M53_15055	COG0425	Belongs to the sulfur carrier protein TusA family
C7M53_15055	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M53_15060	COG2210	Belongs to the sulfur carrier protein TusA family
C7M53_15065	COG1937	Protein conserved in bacteria
C7M53_15105	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C7M53_15110	COG0113	porphobilinogen synthase activity
C7M53_15115	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7M53_15120	COG1121	(ABC) transporter
C7M53_15125	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7M53_15140	COG1942	4-Oxalocrotonate Tautomerase
C7M53_15150	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C7M53_15160	COG1733	regulation of RNA biosynthetic process
C7M53_15165	COG3239	Fatty acid desaturase
C7M53_15170	COG4585	Histidine kinase
C7M53_15175	COG2197	response regulator
C7M53_15180	COG0492	ferredoxin-NADP+ reductase activity
C7M53_15185	COG0747	negative chemotaxis
C7M53_15190	COG0601	transmembrane transport
C7M53_15200	COG0444	Belongs to the ABC transporter superfamily
C7M53_15205	COG4608	Belongs to the ABC transporter superfamily
C7M53_15225	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_15240	COG2124	cytochrome p450
C7M53_15245	COG0730	response to heat
C7M53_15260	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_15265	COG1621	beta-fructofuranosidase activity
C7M53_15270	COG3716	PTS system mannose fructose sorbose family IID component
C7M53_15275	COG3715	PTS system
C7M53_15280	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M53_15285	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M53_15290	COG3933	PFAM sigma-54 factor interaction domain-containing protein
C7M53_15290	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C7M53_15310	COG2169	Transcriptional regulator
C7M53_15315	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7M53_15320	COG0656	L-ascorbic acid biosynthetic process
C7M53_15325	COG2814	Major facilitator Superfamily
C7M53_15330	COG1733	regulation of RNA biosynthetic process
C7M53_15335	COG3340	Belongs to the peptidase S51 family
C7M53_15340	COG1587	Uroporphyrinogen-III synthase
C7M53_15350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M53_15355	COG0583	DNA-binding transcription factor activity
C7M53_15360	COG2814	Major facilitator Superfamily
C7M53_15370	COG2124	cytochrome p450
C7M53_15370	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7M53_15375	COG1309	transcriptional regulator
C7M53_15380	COG1404	Belongs to the peptidase S8 family
C7M53_15385	COG2226	methyltransferase
C7M53_15410	COG0626	cystathionine gamma-synthase activity
C7M53_15415	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7M53_15420	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C7M53_15425	COG2226	methyltransferase
C7M53_15440	COG0768	penicillin binding
C7M53_15445	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C7M53_15450	COG0572	uridine kinase
C7M53_15470	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C7M53_15475	COG3906	Belongs to the UPF0473 family
C7M53_15480	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C7M53_15485	COG4472	Bacterial protein of unknown function (DUF965)
C7M53_15490	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C7M53_15495	COG0628	permease
C7M53_15510	COG3881	PFAM PRC-barrel domain
C7M53_15515	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7M53_15520	COG0457	Tetratricopeptide repeat
C7M53_15525	COG0482	sulfurtransferase activity
C7M53_15530	COG1104	cysteine desulfurase activity
C7M53_15535	COG1959	2 iron, 2 sulfur cluster binding
C7M53_15540	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C7M53_15545	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C7M53_15555	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C7M53_15560	COG0124	histidyl-tRNA synthetase
C7M53_15565	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M53_15565	COG3103	Sh3 type 3 domain protein
C7M53_15565	COG4991	sh3 domain protein
C7M53_15570	COG1490	D-aminoacyl-tRNA deacylase activity
C7M53_15575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C7M53_15580	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7M53_15585	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C7M53_15585	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C7M53_15590	COG5416	Lipopolysaccharide assembly protein A domain
C7M53_15595	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7M53_15595	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7M53_15605	COG2244	polysaccharide biosynthetic process
C7M53_15610	COG2323	membrane
C7M53_15620	COG1862	Preprotein translocase
C7M53_15625	COG0343	queuine tRNA-ribosyltransferase activity
C7M53_15630	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C7M53_15640	COG2255	four-way junction helicase activity
C7M53_15645	COG0632	four-way junction helicase activity
C7M53_15655	COG2112	serine threonine protein kinase
C7M53_15670	COG2318	DinB family
C7M53_15675	COG4195	phage-related replication protein
C7M53_15690	COG0217	transcriptional regulatory protein
C7M53_15700	COG1388	LysM domain
C7M53_15705	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C7M53_15710	COG0157	Belongs to the NadC ModD family
C7M53_15715	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C7M53_15720	COG1104	cysteine desulfurase activity
C7M53_15725	COG1827	regulation of RNA biosynthetic process
C7M53_15730	COG0077	Prephenate dehydratase
C7M53_15735	COG4492	Belongs to the UPF0735 family
C7M53_15740	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C7M53_15745	COG3290	protein histidine kinase activity
C7M53_15750	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C7M53_15755	COG2868	ribosomal protein
C7M53_15760	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C7M53_15765	COG1994	Peptidase M50
C7M53_15770	COG0739	heme binding
C7M53_15775	COG3832	glyoxalase III activity
C7M53_15780	COG0640	Transcriptional regulator
C7M53_15785	COG2894	cell division
C7M53_15790	COG0850	regulation of cytokinetic process
C7M53_15795	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C7M53_15800	COG1792	Involved in formation and maintenance of cell shape
C7M53_15805	COG1077	Cell shape determining protein MreB Mrl
C7M53_15810	COG2003	Belongs to the UPF0758 family
C7M53_15815	COG0424	maF-like protein
C7M53_15825	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C7M53_15830	COG0285	dihydrofolate synthase activity
C7M53_15835	COG0525	valine-tRNA ligase activity
C7M53_15845	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M53_15850	COG1388	LysM domain
C7M53_15855	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C7M53_15860	COG0113	porphobilinogen synthase activity
C7M53_15865	COG1587	Uroporphyrinogen-III synthase
C7M53_15870	COG0181	hydroxymethylbilane synthase activity
C7M53_15875	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7M53_15880	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C7M53_15890	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C7M53_15895	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C7M53_15900	COG0470	DNA polymerase III
C7M53_15900	COG1067	ATP-dependent peptidase activity
C7M53_15905	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C7M53_15910	COG0544	peptidyl-prolyl cis-trans isomerase activity
C7M53_15915	COG1477	protein flavinylation
C7M53_15915	COG0457	Tetratricopeptide repeat
C7M53_15920	COG0066	3-isopropylmalate dehydratase activity
C7M53_15925	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C7M53_15930	COG0473	3-isopropylmalate dehydrogenase activity
C7M53_15935	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C7M53_15940	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C7M53_15945	COG0440	acetolactate synthase activity
C7M53_15950	COG0028	Belongs to the TPP enzyme family
C7M53_15955	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M53_15985	COG5518	Phage portal protein
C7M53_16040	COG5444	nuclease activity
C7M53_16045	COG0457	Tetratricopeptide repeat
C7M53_16065	COG0622	Phosphoesterase
C7M53_16070	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C7M53_16075	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
C7M53_16080	COG5401	PFAM Sporulation and spore germination
C7M53_16085	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C7M53_16090	COG1846	Transcriptional regulator
C7M53_16095	COG2197	response regulator
C7M53_16100	COG4221	oxidoreductase activity
C7M53_16105	COG0824	Thioesterase
C7M53_16110	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C7M53_16115	COG1053	succinate dehydrogenase
C7M53_16120	COG2009	succinate dehydrogenase
C7M53_16125	COG1719	4-vinyl reductase, 4VR
C7M53_16130	COG0527	aspartate kinase activity
C7M53_16140	COG0322	excinuclease ABC activity
C7M53_16145	COG3118	belongs to the thioredoxin family
C7M53_16150	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C7M53_16155	COG2086	electron transfer activity
C7M53_16160	COG1024	Enoyl-CoA hydratase
C7M53_16165	COG1309	transcriptional regulator
C7M53_16170	COG0318	PFAM AMP-dependent synthetase and ligase
C7M53_16175	COG3766	membrane
C7M53_16180	COG1193	negative regulation of DNA recombination
C7M53_16185	COG1796	DNA polymerase
C7M53_16185	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C7M53_16190	COG1286	toxin biosynthetic process
C7M53_16195	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
C7M53_16200	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7M53_16225	COG1137	ATPase activity
C7M53_16240	COG0072	phenylalanine-tRNA ligase activity
C7M53_16240	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M53_16245	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C7M53_16250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7M53_16260	COG1966	Carbon starvation protein
C7M53_16275	COG0395	ABC-type sugar transport system, permease component
C7M53_16280	COG1175	transmembrane transport
C7M53_16285	COG1653	transport
C7M53_16290	COG0371	Dehydrogenase
C7M53_16295	COG0235	Class ii aldolase
C7M53_16300	COG1069	ribulokinase activity
C7M53_16305	COG2160	L-arabinose isomerase activity
C7M53_16310	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M53_16315	COG1363	Peptidase, m42
C7M53_16325	COG3326	Membrane
C7M53_16330	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C7M53_16335	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C7M53_16340	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C7M53_16345	COG1346	cytolysis
C7M53_16355	COG3540	Alkaline phosphatase
C7M53_16360	COG3279	Response regulator of the LytR AlgR family
C7M53_16365	COG3275	phosphorelay sensor kinase activity
C7M53_16380	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C7M53_16390	COG0398	Pfam SNARE associated Golgi protein
C7M53_16395	COG1484	DNA-dependent DNA replication
C7M53_16400	COG3611	Membrane attachment protein
C7M53_16405	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C7M53_16420	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
C7M53_16425	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7M53_16430	COG3866	Pectate lyase
C7M53_16435	COG0237	dephospho-CoA kinase activity
C7M53_16440	COG1971	Probably functions as a manganese efflux pump
C7M53_16445	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C7M53_16450	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M53_16450	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M53_16455	COG5002	protein histidine kinase activity
C7M53_16460	COG0745	RESPONSE REGULATOR receiver
C7M53_16465	COG0039	L-malate dehydrogenase activity
C7M53_16470	COG0538	isocitrate dehydrogenase activity
C7M53_16475	COG0372	Belongs to the citrate synthase family
C7M53_16480	COG2707	UPF0756 membrane protein
C7M53_16485	COG0628	permease
C7M53_16490	COG3030	protein affecting phage T7 exclusion by the F plasmid
C7M53_16500	COG0205	6-phosphofructokinase activity
C7M53_16505	COG0825	malonyl-CoA metabolic process
C7M53_16510	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C7M53_16515	COG0281	malic enzyme
C7M53_16520	COG0587	DNA-directed DNA polymerase activity
C7M53_16540	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C7M53_16550	COG4109	DRTGG domain
C7M53_16555	COG1695	Transcriptional regulator
C7M53_16560	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C7M53_16565	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_16570	COG0165	Argininosuccinate lyase
C7M53_16575	COG0137	argininosuccinate synthase activity
C7M53_16580	COG0521	Mo-molybdopterin cofactor biosynthetic process
C7M53_16585	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C7M53_16590	COG0827	DNA restriction-modification system
C7M53_16595	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C7M53_16600	COG3874	Sporulation protein YtfJ
C7M53_16610	COG1714	RDD family
C7M53_16615	COG0616	signal peptide processing
C7M53_16620	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7M53_16625	COG1566	PFAM secretion protein HlyD family protein
C7M53_16640	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7M53_16650	COG0301	tRNA thio-modification
C7M53_16655	COG1104	cysteine desulfurase activity
C7M53_16660	COG1114	Component of the transport system for branched-chain amino acids
C7M53_16670	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
C7M53_16675	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C7M53_16680	COG1309	transcriptional regulator
C7M53_16685	COG1956	GAF domain-containing protein
C7M53_16690	COG2199	diguanylate cyclase activity
C7M53_16690	COG2203	Gaf domain
C7M53_16695	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C7M53_16710	COG3152	Membrane
C7M53_16715	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C7M53_16720	COG1522	sequence-specific DNA binding
C7M53_16725	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C7M53_16730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7M53_16735	COG0454	-acetyltransferase
C7M53_16740	COG0517	IMP dehydrogenase activity
C7M53_16745	COG0123	including yeast histone deacetylase and acetoin utilization protein
C7M53_16750	COG1360	Flagellar Motor Protein
C7M53_16755	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C7M53_16760	COG1609	Transcriptional regulator
C7M53_16765	COG1605	Chorismate mutase
C7M53_16765	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C7M53_16775	COG3118	belongs to the thioredoxin family
C7M53_16780	COG4980	gas vesicle protein
C7M53_16785	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C7M53_16790	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C7M53_16795	COG1674	ftsk spoiiie
C7M53_16800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M53_16805	COG4848	Belongs to the UPF0354 family
C7M53_16810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M53_16820	COG1363	Peptidase, m42
C7M53_16825	COG5584	Small secreted protein
C7M53_16830	COG0281	malic enzyme
C7M53_16835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M53_16840	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C7M53_16850	COG0510	thiamine kinase activity
C7M53_16855	COG1523	belongs to the glycosyl hydrolase 13 family
C7M53_16860	COG1597	lipid kinase activity
C7M53_16870	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C7M53_16875	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7M53_16890	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M53_16895	COG2252	PERMEase
C7M53_16900	COG1349	DNA-binding transcription factor activity
C7M53_16905	COG1187	pseudouridine synthase activity
C7M53_16910	COG2244	polysaccharide biosynthetic process
C7M53_16915	COG2081	HI0933 family
C7M53_16920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C7M53_16935	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M53_16940	COG0457	Tetratricopeptide repeat
C7M53_16950	COG5578	integral membrane protein
C7M53_16955	COG0673	inositol 2-dehydrogenase activity
C7M53_16960	COG1653	transport
C7M53_16965	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
C7M53_16970	COG4209	transmembrane transport
C7M53_16975	COG2207	Transcriptional regulator
C7M53_16980	COG1653	transport
C7M53_16985	COG0395	ABC-type sugar transport system, permease component
C7M53_16990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M53_16995	COG1073	alpha beta
C7M53_17005	COG0583	DNA-binding transcription factor activity
C7M53_17010	COG0346	lactoylglutathione lyase activity
C7M53_17015	COG0495	leucyl-tRNA aminoacylation
C7M53_17025	COG2814	Major facilitator Superfamily
C7M53_17035	COG2433	Pfam Transposase IS66
C7M53_17040	COG0577	efflux transmembrane transporter activity
C7M53_17045	COG1136	(ABC) transporter
C7M53_17055	COG1131	(ABC) transporter
C7M53_17060	COG1725	Transcriptional regulator
C7M53_17070	COG1242	4 iron, 4 sulfur cluster binding
C7M53_17075	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C7M53_17080	COG1301	dicarboxylic acid transport
C7M53_17090	COG2267	carboxylic ester hydrolase activity
C7M53_17095	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C7M53_17100	COG0671	phosphoesterase, PA-phosphatase related
C7M53_17105	COG0438	transferase activity, transferring glycosyl groups
C7M53_17105	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7M53_17110	COG0367	asparagine synthase
C7M53_17115	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C7M53_17120	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
C7M53_17125	COG1301	dicarboxylic acid transport
C7M53_17135	COG1506	peptidase
C7M53_17140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7M53_17145	COG1116	anion transmembrane transporter activity
C7M53_17150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7M53_17155	COG0494	nUDIX hydrolase
C7M53_17165	COG4824	toxin secretion phage lysis holin
C7M53_17170	COG0783	Belongs to the Dps family
C7M53_17185	COG1854	S-ribosylhomocysteine lyase activity
C7M53_17190	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C7M53_17195	COG0288	reversible hydration of carbon dioxide
C7M53_17200	COG0523	cobalamin synthesis protein
C7M53_17205	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7M53_17210	COG0254	rRNA binding
C7M53_17215	COG1271	oxidase subunit
C7M53_17220	COG1294	oxidase, subunit
C7M53_17235	COG4948	Mandelate Racemase Muconate Lactonizing
C7M53_17240	COG0318	PFAM AMP-dependent synthetase and ligase
C7M53_17245	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C7M53_17250	COG0596	Alpha beta hydrolase
C7M53_17255	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
C7M53_17260	COG1169	isochorismate synthase
C7M53_17265	COG1575	Belongs to the MenA family. Type 1 subfamily
C7M53_17270	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7M53_17275	COG0058	SHG alpha-glucan phosphorylase activity
C7M53_17280	COG0297	glycogen (starch) synthase activity
C7M53_17285	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C7M53_17290	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C7M53_17295	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C7M53_17420	COG1609	Transcriptional regulator
C7M53_17425	COG3859	Proton-coupled thiamine transporter YuaJ
C7M53_17430	COG3764	Sortase (surface protein transpeptidase)
C7M53_17445	COG0457	Tetratricopeptide repeat
C7M53_17450	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
C7M53_17455	COG0569	domain protein
C7M53_17460	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7M53_17470	COG2318	DinB family
C7M53_17480	COG1454	alcohol dehydrogenase
C7M53_17490	COG1510	regulation of RNA biosynthetic process
C7M53_17500	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C7M53_17505	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7M53_17510	COG2140	Oxalate decarboxylase
C7M53_17545	COG1397	ADP-ribosylglycohydrolase
C7M53_17580	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
C7M53_17590	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7M53_17595	COG0726	polysaccharide deacetylase
C7M53_17600	COG1408	metallophosphoesterase
C7M53_17605	COG1968	undecaprenyl-diphosphatase activity
C7M53_17610	COG0628	permease
C7M53_17615	COG0673	inositol 2-dehydrogenase activity
C7M53_17620	COG0693	protein deglycase activity
C7M53_17625	COG0840	transmembrane signaling receptor activity
C7M53_17630	COG0840	transmembrane signaling receptor activity
C7M53_17635	COG0840	transmembrane signaling receptor activity
C7M53_17645	COG2070	2-Nitropropane dioxygenase
C7M53_17650	COG0432	Pfam Uncharacterised protein family UPF0047
C7M53_17655	COG0366	Alpha amylase catalytic
C7M53_17670	COG5297	Belongs to the glycosyl hydrolase family 6
C7M53_17675	COG1253	flavin adenine dinucleotide binding
C7M53_17680	COG2738	Putative neutral zinc metallopeptidase
C7M53_17690	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C7M53_17700	COG2323	membrane
C7M53_17705	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
C7M53_17715	COG0166	Belongs to the GPI family
C7M53_17720	COG1979	alcohol dehydrogenase
C7M53_17725	COG2155	Conserved Protein
C7M53_17730	COG1098	S1 RNA binding domain
C7M53_17735	COG0436	Aminotransferase
C7M53_17740	COG1522	sequence-specific DNA binding
C7M53_17745	COG2267	carboxylic ester hydrolase activity
C7M53_17760	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C7M53_17775	COG5018	Exonuclease
C7M53_17785	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M53_17790	COG3011	Protein conserved in bacteria
C7M53_17800	COG3290	protein histidine kinase activity
C7M53_17805	COG4565	transcriptional regulatory protein
C7M53_17815	COG1183	phosphatidylcholine synthase activity
C7M53_17820	COG0586	Pfam SNARE associated Golgi protein
C7M53_17825	COG0688	phosphatidylethanolamine metabolic process
C7M53_17830	COG3493	citrate carrier protein
C7M53_17840	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7M53_17840	COG2111	Na H antiporter
C7M53_17845	COG2111	Na H antiporter
C7M53_17850	COG1006	Multisubunit Na H antiporter MnhC subunit
C7M53_17855	COG0651	ATP synthesis coupled electron transport
C7M53_17860	COG1863	multisubunit Na H antiporter MnhE subunit
C7M53_17865	COG2212	antiporter activity
C7M53_17870	COG1320	monovalent cation:proton antiporter activity
C7M53_17875	COG2050	protein possibly involved in aromatic compounds catabolism
C7M53_17880	COG2197	response regulator
C7M53_17885	COG4585	Histidine kinase
C7M53_17915	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C7M53_17920	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C7M53_17925	COG1335	isochorismatase
C7M53_17930	COG5506	Protein of unknown function (DUF1694)
C7M53_17945	COG0628	permease
C7M53_17950	COG1959	2 iron, 2 sulfur cluster binding
C7M53_17965	COG1418	mRNA catabolic process
C7M53_17970	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_17980	COG1511	domain protein
C7M53_17985	COG0433	COG0433 Predicted ATPase
C7M53_17985	COG1674	ftsk spoiiie
C7M53_17990	COG4499	WXG100 protein secretion system (Wss), protein YukC
C7M53_17995	COG5417	Belongs to the EsaB family
C7M53_18000	COG4842	Belongs to the WXG100 family
C7M53_18005	COG1115	amino acid carrier protein
C7M53_18010	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C7M53_18010	COG2508	Transcriptional regulator
C7M53_18015	COG0686	Belongs to the AlaDH PNT family
C7M53_18025	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C7M53_18030	COG1268	BioY protein
C7M53_18035	COG2056	Na+-H+ antiporter family
C7M53_18040	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C7M53_18045	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
C7M53_18050	COG3584	3D domain protein
C7M53_18060	COG1252	NADH dehydrogenase
C7M53_18065	COG0492	ferredoxin-NADP+ reductase activity
C7M53_18080	COG0456	acetyltransferase
C7M53_18085	COG0316	Belongs to the HesB IscA family
C7M53_18090	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C7M53_18095	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7M53_18100	COG4844	belongs to the
C7M53_18105	COG1252	NADH dehydrogenase
C7M53_18110	COG5646	InterPro IPR014922
C7M53_18120	COG0457	Tetratricopeptide repeat
C7M53_18125	COG3479	Phenolic acid decarboxylase
C7M53_18135	COG4837	Protein of unknown function (DUF1462)
C7M53_18140	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C7M53_18145	COG4946	Tricorn protease homolog
C7M53_18145	COG0823	Involved in the tonB-independent uptake of proteins
C7M53_18145	COG1506	peptidase
C7M53_18150	COG0083	homoserine kinase activity
C7M53_18155	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C7M53_18160	COG0460	homoserine dehydrogenase
C7M53_18170	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M53_18175	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C7M53_18180	COG0647	UMP catabolic process
C7M53_18185	COG2445	Protein of unknown function DUF86
C7M53_18190	COG4470	Protein conserved in bacteria
C7M53_18205	COG0739	heme binding
C7M53_18215	COG0733	neurotransmitter:sodium symporter activity
C7M53_18225	COG3377	Domain of unknown function (DUF1805)
C7M53_18230	COG0737	Belongs to the 5'-nucleotidase family
C7M53_18235	COG0730	response to heat
C7M53_18240	COG1801	Protein of unknown function DUF72
C7M53_18250	COG3226	Transcriptional regulator
C7M53_18260	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C7M53_18265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M53_18270	COG2508	Transcriptional regulator
C7M53_18275	COG2814	Major facilitator Superfamily
C7M53_18295	COG2356	endonuclease I
C7M53_18305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7M53_18320	COG0457	Tetratricopeptide repeat
C7M53_18325	COG0719	Fe-S assembly protein
C7M53_18330	COG0822	iron-sulfur transferase activity
C7M53_18335	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7M53_18340	COG0719	Fe-S assembly protein
C7M53_18345	COG0396	ATPase activity
C7M53_18355	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C7M53_18365	COG1464	Belongs to the NlpA lipoprotein family
C7M53_18370	COG2011	ABC-type metal ion transport system permease component
C7M53_18375	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7M53_18385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M53_18390	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C7M53_18400	COG0509	glycine decarboxylation via glycine cleavage system
C7M53_18405	COG1393	Belongs to the ArsC family
C7M53_18410	COG1960	acyl-CoA dehydrogenase activity
C7M53_18415	COG0183	Belongs to the thiolase family
C7M53_18420	COG1250	3-hydroxyacyl-CoA dehydrogenase
C7M53_18420	COG1024	Enoyl-CoA hydratase
C7M53_18435	COG5577	PFAM Coat F domain
C7M53_18450	COG1120	ATPase activity
C7M53_18455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M53_18460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M53_18465	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M53_18480	COG1686	Belongs to the peptidase S11 family
C7M53_18485	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_18490	COG0783	Belongs to the Dps family
C7M53_18495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M53_18500	COG0745	RESPONSE REGULATOR receiver
C7M53_18505	COG2770	Histidine kinase
C7M53_18505	COG2205	protein histidine kinase activity
C7M53_18510	COG1309	transcriptional regulator
C7M53_18515	COG0114	fumarate hydratase activity
C7M53_18525	COG0697	spore germination
C7M53_18530	COG0814	amino acid
C7M53_18545	COG2197	response regulator
C7M53_18550	COG4585	Histidine kinase
C7M53_18555	COG4758	membrane
C7M53_18565	COG1842	Phage shock protein A
C7M53_18570	COG4758	membrane
C7M53_18575	COG4677	pectinesterase activity
C7M53_18580	COG2096	Adenosyltransferase
C7M53_18585	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_18595	COG1454	alcohol dehydrogenase
C7M53_18600	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7M53_18605	COG1120	ATPase activity
C7M53_18610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M53_18615	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M53_18620	COG1802	Transcriptional regulator
C7M53_18625	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_18630	COG2258	MOSC domain
C7M53_18635	COG0583	DNA-binding transcription factor activity
C7M53_18645	COG2721	sulfolactate sulfo-lyase activity
C7M53_18650	COG0246	Mannitol dehydrogenase
C7M53_18655	COG1609	Transcriptional regulator
C7M53_18660	COG2211	Major facilitator Superfamily
C7M53_18665	COG1904	glucuronate isomerase
C7M53_18670	COG2205	protein histidine kinase activity
C7M53_18675	COG0745	RESPONSE REGULATOR receiver
C7M53_18680	COG1120	ATPase activity
C7M53_18685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M53_18690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M53_18695	COG0531	amino acid
C7M53_18705	COG1988	membrane-bound metal-dependent
C7M53_18710	COG1368	sulfuric ester hydrolase activity
C7M53_18715	COG2814	Major facilitator Superfamily
C7M53_18720	COG0656	L-ascorbic acid biosynthetic process
C7M53_18725	COG1940	carbohydrate kinase activity
C7M53_18740	COG3973	AAA domain
C7M53_18745	COG2860	membrane
C7M53_18750	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C7M53_18750	COG0456	acetyltransferase
C7M53_18755	COG0456	acetyltransferase
C7M53_18760	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C7M53_18765	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C7M53_18770	COG2217	Heavy metal translocating P-type atpase
C7M53_18775	COG1653	transport
C7M53_18780	COG1175	transmembrane transport
C7M53_18785	COG0395	ABC-type sugar transport system, permease component
C7M53_18790	COG1501	Belongs to the glycosyl hydrolase 31 family
C7M53_18795	COG1472	Belongs to the glycosyl hydrolase 3 family
C7M53_18800	COG1121	(ABC) transporter
C7M53_18805	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7M53_18810	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7M53_18830	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M53_18830	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M53_18830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M53_18845	COG2217	Heavy metal translocating P-type atpase
C7M53_18850	COG2608	mercury ion transmembrane transporter activity
C7M53_18855	COG1937	Protein conserved in bacteria
C7M53_18860	COG0693	protein deglycase activity
C7M53_18865	COG1349	DNA-binding transcription factor activity
C7M53_18870	COG1070	Carbohydrate kinase
C7M53_18875	COG4952	isomerase
C7M53_18885	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_18885	COG3347	Dehydrogenase
C7M53_18890	COG2814	Major facilitator Superfamily
C7M53_18895	COG2814	Major facilitator Superfamily
C7M53_18905	COG2124	cytochrome p450
C7M53_18915	COG1846	Transcriptional regulator
C7M53_18925	COG0673	inositol 2-dehydrogenase activity
C7M53_18930	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C7M53_18945	COG1191	sigma factor activity
C7M53_18955	COG2140	Oxalate decarboxylase
C7M53_19000	COG2323	membrane
C7M53_19005	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
C7M53_19010	COG0662	Cupin 2, conserved barrel domain protein
C7M53_19050	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7M53_19060	COG5280	Phage tail tape measure protein TP901
C7M53_19060	COG3953	SLT domain
C7M53_19120	COG4626	Terminase
C7M53_19120	COG1802	Transcriptional regulator
C7M53_19260	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C7M53_19265	COG0557	exoribonuclease II activity
C7M53_19270	COG1647	Serine aminopeptidase, S33
C7M53_19275	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7M53_19280	COG2002	toxin-antitoxin pair type II binding
C7M53_19285	COG1476	TRANSCRIPTIONal
C7M53_19290	COG1396	sequence-specific DNA binding
C7M53_19295	COG1396	sequence-specific DNA binding
C7M53_19300	COG1174	glycine betaine transport
C7M53_19305	COG1732	Glycine betaine
C7M53_19310	COG1174	glycine betaine transport
C7M53_19320	COG1510	regulation of RNA biosynthetic process
C7M53_19325	COG2095	MarC family integral membrane protein
C7M53_19330	COG3064	Membrane
C7M53_19340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M53_19360	COG0148	phosphopyruvate hydratase activity
C7M53_19365	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C7M53_19370	COG0149	triose-phosphate isomerase activity
C7M53_19375	COG0126	phosphoglycerate kinase activity
C7M53_19385	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7M53_19390	COG2390	Transcriptional regulator
C7M53_19395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M53_19400	COG1113	amino acid transport
C7M53_19420	COG1556	Lactate utilization protein
C7M53_19425	COG1139	Iron-sulfur cluster binding protein
C7M53_19430	COG0247	lactate metabolic process
C7M53_19435	COG2186	Transcriptional regulator
C7M53_19440	COG1620	l-lactate permease
C7M53_19445	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C7M53_19455	COG5039	Polysaccharide pyruvyl transferase
C7M53_19460	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7M53_19465	COG0110	maltose O-acetyltransferase activity
C7M53_19470	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C7M53_19475	COG2244	polysaccharide biosynthetic process
C7M53_19480	COG1216	Glycosyl transferase, family 2
C7M53_19485	COG5039	Polysaccharide pyruvyl transferase
C7M53_19490	COG1216	Glycosyl transferase, family 2
C7M53_19500	COG0438	transferase activity, transferring glycosyl groups
C7M53_19505	COG1215	transferase activity, transferring glycosyl groups
C7M53_19510	COG0438	transferase activity, transferring glycosyl groups
C7M53_19515	COG1086	Polysaccharide biosynthesis protein
C7M53_19520	COG0489	protein tyrosine kinase activity
C7M53_19525	COG3944	biosynthesis protein
C7M53_19530	COG1396	sequence-specific DNA binding
C7M53_19535	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7M53_19540	COG2271	Major facilitator Superfamily
C7M53_19550	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C7M53_19565	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7M53_19575	COG1733	regulation of RNA biosynthetic process
C7M53_19580	COG1902	pentaerythritol trinitrate reductase activity
C7M53_19585	COG1621	beta-fructofuranosidase activity
C7M53_19590	COG1621	beta-fructofuranosidase activity
C7M53_19605	COG0740	serine-type endopeptidase activity
C7M53_19610	COG1611	Belongs to the LOG family
C7M53_19615	COG1694	Mazg nucleotide pyrophosphohydrolase
C7M53_19620	COG1078	dGTPase activity
C7M53_19625	COG0659	secondary active sulfate transmembrane transporter activity
C7M53_19630	COG0288	reversible hydration of carbon dioxide
C7M53_19635	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7M53_19640	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7M53_19645	COG0640	Transcriptional regulator
C7M53_19655	COG2732	(Barnase) inhibitor
C7M53_19660	COG2162	N-hydroxyarylamine O-acetyltransferase activity
C7M53_19665	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M53_19670	COG1481	regulation of sporulation
C7M53_19675	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C7M53_19680	COG1660	Displays ATPase and GTPase activities
C7M53_19685	COG1051	belongs to the nudix hydrolase family
C7M53_19695	COG0492	ferredoxin-NADP+ reductase activity
C7M53_19700	COG0457	Tetratricopeptide repeat
C7M53_19705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M53_19710	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C7M53_19710	COG0140	phosphoribosyl-ATP diphosphatase activity
C7M53_19715	COG0107	imidazoleglycerol-phosphate synthase activity
C7M53_19720	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C7M53_19725	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C7M53_19730	COG0131	Imidazoleglycerol-phosphate dehydratase
C7M53_19735	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C7M53_19740	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C7M53_19745	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
C7M53_19750	COG4990	cell redox homeostasis
C7M53_19755	COG5297	Belongs to the glycosyl hydrolase family 6
C7M53_19760	COG0110	maltose O-acetyltransferase activity
C7M53_19765	COG0546	phosphoglycolate phosphatase activity
C7M53_19770	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
C7M53_19775	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C7M53_19780	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
C7M53_19785	COG1846	Transcriptional regulator
C7M53_19790	COG2814	Major facilitator Superfamily
C7M53_19795	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C7M53_19800	COG1950	PFAM Membrane protein of
C7M53_19805	COG1983	PspC domain protein
C7M53_19810	COG3595	metallopeptidase activity
C7M53_19835	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C7M53_19840	COG0556	nucleotide-excision repair
C7M53_19845	COG4897	Protein conserved in bacteria
C7M53_19855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M53_19865	COG0793	Belongs to the peptidase S41A family
C7M53_19865	COG3409	Peptidoglycan-binding domain 1 protein
C7M53_19870	COG0473	3-isopropylmalate dehydrogenase activity
C7M53_19875	COG3883	PFAM NLP P60 protein
C7M53_19875	COG0791	NLP P60 protein
C7M53_19880	COG2177	Part of the ABC transporter FtsEX involved in
C7M53_19885	COG2884	Cell division ATP-binding protein ftsE
C7M53_19895	COG2010	Cytochrome c
C7M53_19900	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M53_19910	COG0653	protein targeting
C7M53_19915	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C7M53_19930	COG1516	flagellar protein fliS
C7M53_19935	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C7M53_19940	COG1334	flagellar protein FlaG
C7M53_19950	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7M53_19955	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C7M53_19960	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
C7M53_19970	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7M53_19975	COG1256	bacterial-type flagellum assembly
C7M53_19975	COG4786	Flagellar basal body rod
C7M53_19980	COG3418	PFAM FlgN family protein
C7M53_19985	COG2747	anti-sigma28 factor FlgM
C7M53_19995	COG1040	competence protein
C7M53_20005	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C7M53_20010	COG1307	EDD domain protein, DegV family
C7M53_20015	COG2197	response regulator
C7M53_20020	COG4585	Histidine kinase
C7M53_20025	COG1739	Uncharacterized protein family UPF0029
C7M53_20030	COG1316	TRANSCRIPTIONal
C7M53_20040	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7M53_20045	COG0438	transferase activity, transferring glycosyl groups
C7M53_20050	COG1215	transferase activity, transferring glycosyl groups
C7M53_20055	COG3206	protein involved in exopolysaccharide biosynthesis
C7M53_20060	COG3307	-O-antigen
C7M53_20065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M53_20070	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C7M53_20075	COG0438	transferase activity, transferring glycosyl groups
C7M53_20075	COG0297	glycogen (starch) synthase activity
C7M53_20080	COG2244	polysaccharide biosynthetic process
C7M53_20090	COG2247	cell wall binding repeat
C7M53_20090	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M53_20095	COG2385	sporulation resulting in formation of a cellular spore
C7M53_20095	COG2247	cell wall binding repeat
C7M53_20105	COG1316	TRANSCRIPTIONal
C7M53_20110	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C7M53_20115	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7M53_20120	COG1134	teichoic acid transport
C7M53_20125	COG1682	transport, permease protein
C7M53_20140	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M53_20165	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M53_20165	COG0463	Glycosyl transferase, family 2
C7M53_20170	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M53_20175	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C7M53_20180	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
C7M53_20185	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M53_20190	COG4193	domain, Protein
C7M53_20195	COG1482	cell wall glycoprotein biosynthetic process
C7M53_20215	COG0800	Aldolase
C7M53_20220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M53_20225	COG1609	Transcriptional regulator
C7M53_20230	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
C7M53_20235	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_20240	COG1063	alcohol dehydrogenase
C7M53_20245	COG2814	Major facilitator Superfamily
C7M53_20250	COG1316	TRANSCRIPTIONal
C7M53_20255	COG0561	phosphatase activity
C7M53_20260	COG0791	NLP P60 protein
C7M53_20265	COG2843	Capsule synthesis protein
C7M53_20275	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C7M53_20280	COG1609	Transcriptional regulator
C7M53_20285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M53_20290	COG1869	D-ribose catabolic process
C7M53_20295	COG1129	ABC transporter
C7M53_20300	COG1172	Belongs to the binding-protein-dependent transport system permease family
C7M53_20305	COG1879	ABC-type sugar transport system periplasmic component
C7M53_20315	COG3527	Alpha-acetolactate decarboxylase
C7M53_20320	COG0028	Belongs to the TPP enzyme family
C7M53_20325	COG0583	DNA-binding transcription factor activity
C7M53_20330	COG0405	Gamma-glutamyltransferase
C7M53_20335	COG1522	sequence-specific DNA binding
C7M53_20340	COG2059	Chromate
C7M53_20345	COG2059	Chromate
C7M53_20350	COG4464	protein tyrosine phosphatase activity
C7M53_20355	COG3944	biosynthesis protein
C7M53_20365	COG4715	Zinc finger, swim domain protein
C7M53_20370	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C7M53_20375	COG0561	phosphatase activity
C7M53_20380	COG1349	DNA-binding transcription factor activity
C7M53_20390	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_20400	COG3732	PTS system glucitol sorbitol-specific
C7M53_20420	COG0629	single-stranded DNA binding
C7M53_20435	COG1970	mechanosensitive ion channel activity
C7M53_20440	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7M53_20445	COG4786	Flagellar basal body rod
C7M53_20450	COG4786	Flagellar basal body rod
C7M53_20455	COG1077	Cell shape determining protein MreB Mrl
C7M53_20460	COG1609	Transcriptional regulator
C7M53_20470	COG1846	Transcriptional regulator
C7M53_20475	COG2814	Major facilitator Superfamily
C7M53_20480	COG0671	phosphoesterase, PA-phosphatase related
C7M53_20485	COG1227	inorganic diphosphatase activity
C7M53_20490	COG3546	catalase activity
C7M53_20495	COG3361	conserved protein (COG2071)
C7M53_20500	COG0517	IMP dehydrogenase activity
C7M53_20505	COG0598	Magnesium transport protein CorA
C7M53_20510	COG1253	flavin adenine dinucleotide binding
C7M53_20515	COG0004	ammonium transporteR
C7M53_20520	COG0347	Belongs to the P(II) protein family
C7M53_20525	COG0740	serine-type endopeptidase activity
C7M53_20535	COG0739	heme binding
C7M53_20540	COG1247	-acetyltransferase
C7M53_20550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7M53_20555	COG0477	Major facilitator Superfamily
C7M53_20560	COG3251	PFAM MbtH domain protein
C7M53_20565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M53_20570	COG3433	isochorismatase activity
C7M53_20570	COG1535	isochorismatase
C7M53_20575	COG1021	2,3-dihydroxybenzoate-AMP ligase
C7M53_20580	COG1169	isochorismate synthase
C7M53_20585	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_20590	COG2819	hydrolase of the alpha beta superfamily
C7M53_20595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M53_20600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M53_20605	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M53_20610	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M53_20610	COG2207	Transcriptional regulator
C7M53_20620	COG2910	NAD(P)H-binding
C7M53_20625	COG1959	2 iron, 2 sulfur cluster binding
C7M53_20630	COG1994	Peptidase M50
C7M53_20635	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C7M53_20640	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C7M53_20650	COG3383	formate dehydrogenase (NAD+) activity
C7M53_20655	COG2304	oxidoreductase activity
C7M53_20660	COG2304	oxidoreductase activity
C7M53_20665	COG2385	sporulation resulting in formation of a cellular spore
C7M53_20670	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7M53_20680	COG4836	Membrane
C7M53_20685	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C7M53_20690	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C7M53_20695	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C7M53_20700	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C7M53_20705	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7M53_20710	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C7M53_20715	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7M53_20735	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C7M53_20740	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C7M53_20745	COG4475	Protein of unknown function (DUF436)
C7M53_20750	COG0698	ribose 5-phosphate isomerase
C7M53_20755	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7M53_20760	COG1971	Probably functions as a manganese efflux pump
C7M53_20765	COG0009	L-threonylcarbamoyladenylate synthase
C7M53_20770	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C7M53_20780	COG0738	Major facilitator superfamily
C7M53_20790	COG0561	phosphatase activity
C7M53_20795	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7M53_20800	COG1609	Transcriptional regulator
C7M53_20805	COG2890	protein-(glutamine-N5) methyltransferase activity
C7M53_20810	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C7M53_20815	COG0346	lactoylglutathione lyase activity
C7M53_20820	COG0789	Transcriptional regulator
C7M53_20825	COG0679	Auxin Efflux Carrier
C7M53_20830	COG0281	malic enzyme
C7M53_20835	COG1435	thymidine kinase activity
C7M53_20840	COG0254	rRNA binding
C7M53_20845	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C7M53_20850	COG1494	fructose-1,6-bisphosphatase
C7M53_20855	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7M53_20860	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C7M53_20865	COG0191	fructose-bisphosphate aldolase activity
C7M53_20870	COG2204	response regulator
C7M53_20875	COG4821	SIS domain
C7M53_20880	COG0504	CTP synthase activity
C7M53_20885	COG3343	RNA polymerase activity
C7M53_20890	COG1960	acyl-CoA dehydrogenase activity
C7M53_20895	COG1960	acyl-CoA dehydrogenase activity
C7M53_20900	COG1250	3-hydroxyacyl-CoA dehydrogenase
C7M53_20905	COG0183	Belongs to the thiolase family
C7M53_20910	COG0247	lactate metabolic process
C7M53_20910	COG2181	nitrate reductase activity
C7M53_20915	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7M53_20925	COG0018	arginyl-trna synthetase
C7M53_20930	COG4506	Protein conserved in bacteria
C7M53_20935	COG0010	Belongs to the arginase family
C7M53_20940	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
C7M53_20955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M53_20965	COG1994	Peptidase M50
C7M53_20970	COG1942	4-Oxalocrotonate Tautomerase
C7M53_20980	COG3465	dGTPase activity
C7M53_20985	COG1078	dGTPase activity
C7M53_20990	COG4844	belongs to the
C7M53_21015	COG2814	Major facilitator Superfamily
C7M53_21040	COG1414	Transcriptional regulator
C7M53_21050	COG0280	phosphate acetyltransferase
C7M53_21070	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7M53_21090	COG1131	(ABC) transporter
C7M53_21105	COG2363	Small membrane protein
C7M53_21110	COG2233	PERMEase
C7M53_21120	COG1012	belongs to the aldehyde dehydrogenase family
C7M53_21125	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C7M53_21130	COG1216	Glycosyl transferase, family 2
C7M53_21135	COG0351	phosphomethylpyrimidine kinase
C7M53_21145	COG1621	beta-fructofuranosidase activity
C7M53_21150	COG1263	PTS System
C7M53_21150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M53_21155	COG3711	transcriptional antiterminator
C7M53_21165	COG1404	Belongs to the peptidase S8 family
C7M53_21175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M53_21180	COG0778	Nitroreductase
C7M53_21185	COG1473	amidohydrolase
C7M53_21190	COG0772	Belongs to the SEDS family
C7M53_21195	COG0772	Belongs to the SEDS family
C7M53_21220	COG0456	acetyltransferase
C7M53_21255	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C7M53_21265	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C7M53_21270	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7M53_21275	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7M53_21295	COG3162	membrane
C7M53_21300	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M53_21305	COG1070	Carbohydrate kinase
C7M53_21310	COG2115	Belongs to the xylose isomerase family
C7M53_21320	COG0352	thiamine-phosphate diphosphorylase activity
C7M53_21325	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
C7M53_21330	COG0583	DNA-binding transcription factor activity
C7M53_21345	COG1380	Effector of murein hydrolase LrgA
C7M53_21350	COG1346	cytolysis
C7M53_21360	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M53_21365	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C7M53_21370	COG0346	lactoylglutathione lyase activity
C7M53_21375	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7M53_21380	COG1442	glycosyl transferase family 8
C7M53_21390	COG4585	Histidine kinase
C7M53_21395	COG2197	response regulator
C7M53_21405	COG5522	Integral membrane protein (intg_mem_TP0381)
C7M53_21410	COG2271	Major facilitator Superfamily
C7M53_21415	COG4948	Mandelate Racemase Muconate Lactonizing
C7M53_21420	COG0800	Aldolase
C7M53_21425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M53_21435	COG2234	aminopeptidase activity
C7M53_21440	COG0477	Major facilitator Superfamily
C7M53_21450	COG2357	RelA SpoT domain protein
C7M53_21465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M53_21470	COG1696	Membrane protein involved in D-alanine export
C7M53_21475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M53_21480	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
C7M53_21485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M53_21490	COG2814	Major facilitator Superfamily
C7M53_21495	COG1486	melibiose metabolic process
C7M53_21500	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7M53_21505	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M53_21510	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M53_21515	COG3711	transcriptional antiterminator
C7M53_21515	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M53_21520	COG2094	Belongs to the DNA glycosylase MPG family
C7M53_21530	COG0372	Belongs to the citrate synthase family
C7M53_21535	COG2079	MmgE PrpD family protein
C7M53_21540	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C7M53_21555	COG1132	(ABC) transporter
C7M53_21560	COG2755	lipolytic protein G-D-S-L family
C7M53_21575	COG2814	Major facilitator Superfamily
C7M53_21580	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M53_21585	COG1131	(ABC) transporter
C7M53_21605	COG1595	DNA-templated transcription, initiation
C7M53_21610	COG2814	Major facilitator Superfamily
C7M53_21615	COG0753	catalase activity
C7M53_21620	COG0753	catalase activity
C7M53_21625	COG0735	belongs to the Fur family
C7M53_21635	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M53_21640	COG1131	(ABC) transporter
C7M53_21655	COG1131	(ABC) transporter
C7M53_21705	COG3866	Pectate lyase
C7M53_21710	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C7M53_21715	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C7M53_21720	COG4988	ABC transporter
C7M53_21725	COG1294	oxidase, subunit
C7M53_21730	COG1271	oxidase subunit
C7M53_21740	COG2116	formate transmembrane transporter activity
C7M53_21750	COG0281	malic enzyme
C7M53_21755	COG1757	Na H antiporter
C7M53_21760	COG1027	Aspartate ammonia-lyase
C7M53_21765	COG0252	asparaginase activity
C7M53_21770	COG1396	sequence-specific DNA binding
C7M53_21775	COG2706	6-phosphogluconolactonase activity
C7M53_21780	COG0745	RESPONSE REGULATOR receiver
C7M53_21785	COG2205	protein histidine kinase activity
C7M53_21795	COG1136	(ABC) transporter
C7M53_21800	COG0577	efflux transmembrane transporter activity
C7M53_21805	COG5294	Protein conserved in bacteria
C7M53_21815	COG0726	polysaccharide deacetylase
C7M53_21820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M53_21830	COG3493	citrate carrier protein
C7M53_21835	COG0584	glycerophosphoryl diester phosphodiesterase
C7M53_21850	COG1368	sulfuric ester hydrolase activity
C7M53_21860	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M53_21880	COG2235	arginine
C7M53_21885	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C7M53_21895	COG0549	Belongs to the carbamate kinase family
C7M53_21905	COG2723	6-phospho-beta-galactosidase activity
C7M53_21910	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M53_21920	COG1595	DNA-templated transcription, initiation
C7M53_21930	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7M53_21940	COG1621	beta-fructofuranosidase activity
C7M53_21945	COG2223	nitrite transmembrane transporter activity
C7M53_21955	COG1609	Transcriptional regulator
C7M53_21970	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7M53_21975	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C7M53_21980	COG0463	Glycosyl transferase, family 2
C7M53_21985	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7M53_22015	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7M53_22020	COG0753	catalase activity
C7M53_22020	COG0693	protein deglycase activity
C7M53_22030	COG2723	6-phospho-beta-galactosidase activity
C7M53_22035	COG1263	PTS System
C7M53_22035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M53_22035	COG2190	(PTS) system
C7M53_22040	COG3711	transcriptional antiterminator
C7M53_22045	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C7M53_22050	COG1122	ATPase activity
C7M53_22055	COG4721	ABC-type cobalt transport system, permease component
C7M53_22065	COG2224	Isocitrate lyase
C7M53_22070	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C7M53_22080	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C7M53_22085	COG0577	efflux transmembrane transporter activity
C7M53_22090	COG1136	(ABC) transporter
C7M53_22095	COG2205	protein histidine kinase activity
C7M53_22100	COG0745	RESPONSE REGULATOR receiver
C7M53_22105	COG2723	6-phospho-beta-galactosidase activity
C7M53_22110	COG2190	(PTS) system
C7M53_22110	COG1263	PTS System
C7M53_22110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M53_22120	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
C7M53_22140	COG0513	Belongs to the DEAD box helicase family
C7M53_22170	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C7M53_22175	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7M53_22180	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C7M53_22185	COG2390	Transcriptional regulator
C7M53_22195	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C7M53_22200	COG3706	GGDEF domain
C7M53_22205	COG5298	Protein conserved in bacteria
C7M53_22220	COG3977	Valine--pyruvate aminotransferase
C7M53_22235	COG1181	Belongs to the D-alanine--D-alanine ligase family
C7M53_22245	COG0191	fructose-bisphosphate aldolase activity
C7M53_22250	COG1082	Xylose isomerase domain protein TIM barrel
C7M53_22255	COG1082	Xylose isomerase domain protein TIM barrel
C7M53_22260	COG0673	inositol 2-dehydrogenase activity
C7M53_22265	COG2814	Major facilitator Superfamily
C7M53_22270	COG1082	Xylose isomerase domain protein TIM barrel
C7M53_22275	COG3962	Belongs to the TPP enzyme family
C7M53_22280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M53_22285	COG3718	enzyme involved in inositol metabolism
C7M53_22290	COG1012	belongs to the aldehyde dehydrogenase family
C7M53_22295	COG1349	DNA-binding transcription factor activity
C7M53_22300	COG0667	Aldo Keto reductase
C7M53_22305	COG0584	glycerophosphoryl diester phosphodiesterase
C7M53_22310	COG2271	Major facilitator Superfamily
C7M53_22315	COG0326	Molecular chaperone. Has ATPase activity
C7M53_22320	COG0488	(ABC) transporter
C7M53_22325	COG0561	phosphatase activity
C7M53_22345	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M53_22375	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
C7M53_22380	COG0577	efflux transmembrane transporter activity
C7M53_22385	COG1136	(ABC) transporter
C7M53_22390	COG2205	protein histidine kinase activity
C7M53_22395	COG0745	RESPONSE REGULATOR receiver
C7M53_22405	COG0840	transmembrane signaling receptor activity
C7M53_22405	COG5278	phosphoserine phosphatase activity
C7M53_22410	COG1115	amino acid carrier protein
C7M53_22415	COG0686	Belongs to the AlaDH PNT family
C7M53_22420	COG3867	Arabinogalactan endo-beta-1,4-galactanase
C7M53_22425	COG1874	Beta-galactosidase
C7M53_22430	COG3833	ABC-type maltose transport systems, permease component
C7M53_22435	COG1175	transmembrane transport
C7M53_22440	COG2182	Extracellular solute-binding protein
C7M53_22445	COG1609	Transcriptional regulator
C7M53_22455	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7M53_22460	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C7M53_22465	COG1940	carbohydrate kinase activity
C7M53_22490	COG1454	alcohol dehydrogenase
C7M53_22490	COG1012	belongs to the aldehyde dehydrogenase family
C7M53_22495	COG0450	alkyl hydroperoxide reductase
C7M53_22500	COG3634	alkyl hydroperoxide reductase activity
C7M53_22525	COG1131	(ABC) transporter
C7M53_22530	COG0842	Transport permease protein
C7M53_22540	COG2197	response regulator
C7M53_22565	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C7M53_22580	COG0456	acetyltransferase
C7M53_22595	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M53_22600	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C7M53_22605	COG4853	Protein conserved in bacteria
C7M53_22610	COG4863	YycH protein
C7M53_22615	COG5002	protein histidine kinase activity
C7M53_22620	COG0745	RESPONSE REGULATOR receiver
C7M53_22645	COG1051	belongs to the nudix hydrolase family
C7M53_22650	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C7M53_22660	COG0305	Participates in initiation and elongation during chromosome replication
C7M53_22675	COG3093	addiction module antidote protein HigA
C7M53_22680	COG2807	transmembrane transport
C7M53_22685	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C7M53_22690	COG0363	glucosamine-6-phosphate deaminase activity
C7M53_22700	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C7M53_22705	COG1263	PTS System
C7M53_22705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M53_22710	COG0359	binds to the 23S rRNA
C7M53_22715	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
C7M53_22720	COG4241	membrane
C7M53_22725	COG5577	PFAM Coat F domain
C7M53_22735	COG0659	secondary active sulfate transmembrane transporter activity
C7M53_22740	COG2271	Major facilitator Superfamily
C7M53_22745	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C7M53_22750	COG0629	single-stranded DNA binding
C7M53_22755	COG0360	Binds together with S18 to 16S ribosomal RNA
C7M53_22760	COG0012	GTP binding
C7M53_22770	COG4481	Protein conserved in bacteria
C7M53_22775	COG3949	Membrane
C7M53_22785	COG1475	DNA binding
C7M53_22790	COG1192	Involved in chromosome partitioning
C7M53_22795	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C7M53_22805	COG1475	DNA binding
C7M53_22810	COG0357	Ribosomal RNA small subunit methyltransferase G
C7M53_22815	COG0445	tRNA wobble uridine modification
C7M53_22820	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C7M53_22825	COG1847	R3H domain protein
C7M53_22830	COG0706	membrane insertase activity
C7M53_22835	COG0594	ribonuclease P activity
C7M53_22840	COG0230	Belongs to the bacterial ribosomal protein bL34 family
C7M53_22885	COG5644	endopeptidase inhibitor activity
C7M53_22895	COG1196	nuclear chromosome segregation
C7M53_22895	COG0741	lytic transglycosylase activity
C7M53_22895	COG0739	heme binding
C7M53_22910	COG1988	membrane-bound metal-dependent
C7M53_22955	COG2336	PFAM SpoVT AbrB
C7M53_22960	COG2337	Toxic component of a toxin-antitoxin (TA) module
C7M53_22965	COG0457	Tetratricopeptide repeat
C7M53_23020	COG2003	Belongs to the UPF0758 family
C7M53_23040	COG3209	COG3209 Rhs family protein
C7M53_23060	COG0328	RNA-DNA hybrid ribonuclease activity
C7M53_23190	COG5280	Phage tail tape measure protein TP901
C7M53_23190	COG3953	SLT domain
C7M53_23225	COG4824	toxin secretion phage lysis holin
C7M53_23230	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7M53_23235	COG1192	Involved in chromosome partitioning