locus-tag	class	description
BMD_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BMD_0002	COG0592	DNA-directed DNA polymerase activity
BMD_0003	COG2501	S4 domain
BMD_0004	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BMD_0005	COG0187	DNA topoisomerase II activity
BMD_0006	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BMD_0013	COG0517	IMP dehydrogenase activity
BMD_0013	COG0516	GMP reductase activity
BMD_0016	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BMD_0019	COG1428	Deoxynucleoside kinase
BMD_0020	COG1428	Deoxynucleoside kinase
BMD_0021	COG3858	chitin binding
BMD_0021	COG1388	LysM domain
BMD_0022	COG1335	isochorismatase
BMD_0023	COG0590	tRNA wobble adenosine to inosine editing
BMD_0024	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BMD_0025	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BMD_0026	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BMD_0045	COG1982	Orn Lys Arg decarboxylase major
BMD_0046	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BMD_0047	COG3870	Protein conserved in bacteria
BMD_0048	COG0470	DNA polymerase III
BMD_0049	COG1774	PSP1 C-terminal conserved region
BMD_0050	COG4467	Involved in initiation control of chromosome replication
BMD_0051	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BMD_0052	COG2827	Endonuclease containing a URI domain
BMD_0053	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BMD_0054	COG2002	toxin-antitoxin pair type II binding
BMD_0056	COG0084	hydrolase, TatD family'
BMD_0058	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BMD_0061	COG4466	Protein conserved in bacteria
BMD_0064	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BMD_0065	COG0251	oxidation-reduction process
BMD_0066	COG2088	sporulation resulting in formation of a cellular spore
BMD_0067	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BMD_0068	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BMD_0069	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BMD_0070	COG0193	aminoacyl-tRNA hydrolase activity
BMD_0072	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BMD_0074	COG2002	toxin-antitoxin pair type II binding
BMD_0075	COG2244	polysaccharide biosynthetic process
BMD_0076	COG3956	TIGRFAM MazG family protein
BMD_0077	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BMD_0080	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BMD_0081	COG1098	S1 RNA binding domain
BMD_0085	COG2304	oxidoreductase activity
BMD_0086	COG0515	serine threonine protein kinase
BMD_0087	COG0037	tRNA processing
BMD_0089	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BMD_0090	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BMD_0091	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BMD_0092	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BMD_0093	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BMD_0094	COG0512	Glutamine amidotransferase of anthranilate synthase
BMD_0095	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BMD_0096	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BMD_0097	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BMD_0098	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BMD_0103	COG3880	PFAM UvrB UvrC protein
BMD_0104	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BMD_0105	COG0542	response to heat
BMD_0106	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BMD_0107	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BMD_0108	COG4956	integral membrane protein (PIN domain superfamily)
BMD_0109	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BMD_0111	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BMD_0112	COG1045	serine acetyltransferase
BMD_0113	COG0215	cysteine-tRNA ligase activity
BMD_0115	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BMD_0116	COG3688	RNA-binding protein containing a PIN domain
BMD_0118	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BMD_0119	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BMD_0120	COG0250	Participates in transcription elongation, termination and antitermination
BMD_0122	COG0081	regulation of translation
BMD_0123	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BMD_0125	COG2813	Specifically methylates the guanine in position
BMD_0126	COG0085	RNA polymerase activity
BMD_0127	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BMD_0128	COG1358	cellular component organization or biogenesis
BMD_0129	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BMD_0130	COG0049	tRNA binding
BMD_0132	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BMD_0133	COG0051	transcription antitermination factor activity, RNA binding
BMD_0134	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BMD_0135	COG0088	Forms part of the polypeptide exit tunnel
BMD_0136	COG0089	rRNA binding
BMD_0137	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BMD_0138	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BMD_0139	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BMD_0140	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BMD_0141	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BMD_0142	COG0255	Belongs to the universal ribosomal protein uL29 family
BMD_0143	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BMD_0144	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BMD_0147	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BMD_0148	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BMD_0151	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BMD_0152	COG1841	ribosomal large subunit assembly
BMD_0154	COG0201	protein transport
BMD_0155	COG0563	adenylate kinase activity
BMD_0156	COG0024	Methionine aminopeptidase
BMD_0157	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BMD_0158	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BMD_0160	COG0202	RNA polymerase activity
BMD_0161	COG0203	ribosomal protein L17
BMD_0162	COG1122	ATPase activity
BMD_0163	COG1122	ATPase activity
BMD_0164	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BMD_0165	COG0101	tRNA pseudouridine synthase activity
BMD_0166	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BMD_0169	COG0860	N-Acetylmuramoyl-L-alanine amidase
BMD_0170	COG0489	protein tyrosine kinase activity
BMD_0171	COG0583	DNA-binding transcription factor activity
BMD_0173	COG2194	sulfuric ester hydrolase activity
BMD_0174	COG0726	polysaccharide deacetylase
BMD_0187	COG1595	DNA-templated transcription, initiation
BMD_0188	COG5662	AntiSigma factor
BMD_0189	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BMD_0191	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BMD_0192	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BMD_0195	COG1388	LysM domain
BMD_0195	COG3103	Sh3 type 3 domain protein
BMD_0195	COG0791	NLP P60 protein
BMD_0196	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BMD_0196	COG2213	PTS system mannitol-specific
BMD_0197	COG3711	transcriptional antiterminator
BMD_0198	COG0246	Mannitol dehydrogenase
BMD_0200	COG1376	ErfK ybiS ycfS ynhG family protein
BMD_0201	COG1970	mechanosensitive ion channel activity
BMD_0202	COG1368	sulfuric ester hydrolase activity
BMD_0205	COG1176	ABC-type spermidine putrescine transport system, permease component I
BMD_0206	COG1177	transmembrane transport
BMD_0207	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BMD_0209	COG0745	RESPONSE REGULATOR receiver
BMD_0210	COG5002	protein histidine kinase activity
BMD_0213	COG1181	Belongs to the D-alanine--D-alanine ligase family
BMD_0214	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BMD_0215	COG0513	Belongs to the DEAD box helicase family
BMD_0216	COG4294	response to UV
BMD_0217	COG0705	Rhomboid family
BMD_0218	COG0736	holo-[acyl-carrier-protein] synthase activity
BMD_0219	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BMD_0220	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BMD_0221	COG0864	Transcriptional regulator
BMD_0222	COG2337	Toxic component of a toxin-antitoxin (TA) module
BMD_0223	COG1366	Belongs to the anti-sigma-factor antagonist family
BMD_0224	COG1366	Belongs to the anti-sigma-factor antagonist family
BMD_0225	COG2172	sigma factor antagonist activity
BMD_0226	COG2208	phosphoserine phosphatase activity
BMD_0227	COG1366	Belongs to the anti-sigma-factor antagonist family
BMD_0229	COG1191	sigma factor activity
BMD_0230	COG2208	phosphoserine phosphatase activity
BMD_0231	COG2183	response to ionizing radiation
BMD_0250	COG0802	atpase or kinase
BMD_0251	COG1214	PFAM Peptidase M22, glycoprotease
BMD_0252	COG0456	acetyltransferase
BMD_0254	COG0488	(ABC) transporter
BMD_0255	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BMD_0256	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BMD_0257	COG0805	protein transport
BMD_0259	COG1266	CAAX protease self-immunity
BMD_0260	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BMD_0261	COG0459	protein refolding
BMD_0262	COG0714	Associated with various cellular activities
BMD_0263	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BMD_0264	COG1305	Transglutaminase-like
BMD_0265	COG0519	Catalyzes the synthesis of GMP from XMP
BMD_0265	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BMD_0266	COG2252	PERMEase
BMD_0271	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BMD_0272	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BMD_0273	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BMD_0274	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BMD_0275	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BMD_0276	COG0047	phosphoribosylformylglycinamidine synthase activity
BMD_0277	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BMD_0278	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BMD_0279	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BMD_0280	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BMD_0281	COG0138	bifunctional purine biosynthesis protein purh
BMD_0282	COG0151	Belongs to the GarS family
BMD_0284	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BMD_0285	COG4496	protein, YerC YecD
BMD_0286	COG0423	glycine-tRNA ligase activity
BMD_0288	COG0210	DNA helicase
BMD_0290	COG4851	CamS sex pheromone cAM373 precursor
BMD_0292	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BMD_0293	COG0154	amidase activity
BMD_0295	COG1597	lipid kinase activity
BMD_0299	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BMD_0301	COG0166	Belongs to the GPI family
BMD_0302	COG1744	ABC transporter substrate-binding protein PnrA-like
BMD_0303	COG3852	Histidine kinase
BMD_0304	COG0024	Methionine aminopeptidase
BMD_0305	COG2706	6-phosphogluconolactonase activity
BMD_0307	COG4978	Transcriptional regulator
BMD_0307	COG0789	Transcriptional regulator
BMD_0308	COG2814	Major facilitator Superfamily
BMD_0310	COG1876	peptidase activity
BMD_0311	COG1126	abc transporter atp-binding protein
BMD_0312	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BMD_0313	COG0765	amino acid transport
BMD_0314	COG0765	amino acid transport
BMD_0315	COG1113	amino acid transport
BMD_0316	COG2733	membrane
BMD_0317	COG3212	peptidase
BMD_0319	COG3850	Histidine kinase
BMD_0319	COG5002	protein histidine kinase activity
BMD_0320	COG0745	RESPONSE REGULATOR receiver
BMD_0321	COG2205	protein histidine kinase activity
BMD_0322	COG0745	RESPONSE REGULATOR receiver
BMD_0323	COG2311	Membrane
BMD_0326	COG0671	phosphoesterase, PA-phosphatase related
BMD_0327	COG1764	response to oxidative stress
BMD_0328	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BMD_0330	COG2259	Doxx family
BMD_0331	COG0693	protein deglycase activity
BMD_0333	COG2318	DinB family
BMD_0335	COG1115	amino acid carrier protein
BMD_0338	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BMD_0339	COG0598	Magnesium transport protein CorA
BMD_0340	COG3290	protein histidine kinase activity
BMD_0341	COG4565	transcriptional regulatory protein
BMD_0344	COG4191	Histidine kinase
BMD_0345	COG0513	Belongs to the DEAD box helicase family
BMD_0349	COG4842	Belongs to the WXG100 family
BMD_0350	COG5417	Belongs to the EsaB family
BMD_0351	COG4499	WXG100 protein secretion system (Wss), protein YukC
BMD_0352	COG0433	COG0433 Predicted ATPase
BMD_0352	COG1674	ftsk spoiiie
BMD_0353	COG1511	domain protein
BMD_0356	COG2356	endonuclease I
BMD_0358	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BMD_0361	COG0488	(ABC) transporter
BMD_0363	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BMD_0365	COG1959	2 iron, 2 sulfur cluster binding
BMD_0366	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BMD_0366	COG1017	nitric oxide dioxygenase activity
BMD_0367	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BMD_0368	COG0693	protein deglycase activity
BMD_0369	COG2340	Cysteine-rich secretory protein family
BMD_0370	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BMD_0371	COG4840	Belongs to the UPF0435 family
BMD_0372	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BMD_0373	COG4980	gas vesicle protein
BMD_0374	COG1295	ribonuclease BN
BMD_0375	COG2217	Heavy metal translocating P-type atpase
BMD_0377	COG0640	Transcriptional regulator
BMD_0379	COG0477	Major facilitator Superfamily
BMD_0380	COG3479	Phenolic acid decarboxylase
BMD_0382	COG3871	stress protein (general stress protein 26)
BMD_0383	COG0387	Pfam Sodium calcium exchanger
BMD_0385	COG0535	radical SAM domain protein
BMD_0389	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BMD_0391	COG1113	amino acid transport
BMD_0392	COG5002	protein histidine kinase activity
BMD_0396	COG1090	epimerase
BMD_0398	COG4221	oxidoreductase activity
BMD_0402	COG1988	membrane-bound metal-dependent
BMD_0403	COG1194	a g-specific adenine glycosylase
BMD_0405	COG1028	Short-chain dehydrogenase reductase Sdr
BMD_0408	COG3557	Belongs to the UPF0374 family
BMD_0409	COG1132	(ABC) transporter
BMD_0410	COG4129	membrane
BMD_0411	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BMD_0412	COG4555	ABC transporter
BMD_0416	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BMD_0417	COG0735	belongs to the Fur family
BMD_0440	COG3382	B3 4 domain protein
BMD_0443	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BMD_0444	COG2766	serine protein kinase
BMD_0448	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BMD_0450	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BMD_0452	COG1968	undecaprenyl-diphosphatase activity
BMD_0453	COG1301	dicarboxylic acid transport
BMD_0455	COG0586	Pfam SNARE associated Golgi protein
BMD_0456	COG2217	Heavy metal translocating P-type atpase
BMD_0457	COG0531	amino acid
BMD_0461	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BMD_0463	COG1175	transmembrane transport
BMD_0466	COG0584	glycerophosphoryl diester phosphodiesterase
BMD_0469	COG4948	Mandelate Racemase Muconate Lactonizing
BMD_0478	COG3584	3D domain protein
BMD_0478	COG3583	domain protein
BMD_0479	COG1876	peptidase activity
BMD_0481	COG3103	Sh3 type 3 domain protein
BMD_0483	COG0456	acetyltransferase
BMD_0483	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BMD_0484	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BMD_0489	COG1609	Transcriptional regulator
BMD_0490	COG2814	Major facilitator Superfamily
BMD_0491	COG0673	inositol 2-dehydrogenase activity
BMD_0496	COG1609	Transcriptional regulator
BMD_0500	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BMD_0501	COG1522	sequence-specific DNA binding
BMD_0505	COG2814	Major facilitator Superfamily
BMD_0506	COG1309	transcriptional regulator
BMD_0507	COG1187	pseudouridine synthase activity
BMD_0510	COG1942	4-Oxalocrotonate Tautomerase
BMD_0511	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BMD_0514	COG2851	Citrate transporter
BMD_0517	COG0084	hydrolase, TatD family'
BMD_0519	COG0628	permease
BMD_0522	COG0604	alcohol dehydrogenase
BMD_0523	COG1620	l-lactate permease
BMD_0525	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BMD_0526	COG0840	transmembrane signaling receptor activity
BMD_0527	COG0564	pseudouridine synthase activity
BMD_0529	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BMD_0531	COG3153	acetyltransferase
BMD_0531	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BMD_0532	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BMD_0533	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BMD_0535	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BMD_0536	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BMD_0537	COG1268	BioY protein
BMD_0540	COG2719	SpoVR family
BMD_0542	COG1959	2 iron, 2 sulfur cluster binding
BMD_0543	COG0604	alcohol dehydrogenase
BMD_0545	COG1126	abc transporter atp-binding protein
BMD_0546	COG0765	amino acid transport
BMD_0547	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BMD_0548	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BMD_0549	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BMD_0551	COG0352	thiamine-phosphate diphosphorylase activity
BMD_0552	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BMD_0555	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BMD_0556	COG0351	phosphomethylpyrimidine kinase
BMD_0559	COG0702	epimerase
BMD_0560	COG1253	flavin adenine dinucleotide binding
BMD_0563	COG3842	ATPase activity
BMD_0564	COG2508	Transcriptional regulator
BMD_0567	COG0189	ligase activity
BMD_0568	COG0189	ligase activity
BMD_0570	COG3679	Belongs to the UPF0342 family
BMD_0571	COG0561	phosphatase activity
BMD_0573	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BMD_0574	COG0318	PFAM AMP-dependent synthetase and ligase
BMD_0575	COG1024	Enoyl-CoA hydratase
BMD_0578	COG4152	abc transporter atp-binding protein
BMD_0579	COG1668	transmembrane transport
BMD_0580	COG3481	metal-dependent phosphohydrolase, HD sub domain
BMD_0582	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BMD_0585	COG1846	Transcriptional regulator
BMD_0588	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BMD_0589	COG1695	Transcriptional regulator
BMD_0590	COG2153	protein acetylation
BMD_0591	COG2755	lipolytic protein G-D-S-L family
BMD_0591	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BMD_0592	COG0537	adenosine 5'-monophosphoramidase activity
BMD_0593	COG1131	(ABC) transporter
BMD_0594	COG4473	ABC transporter
BMD_0596	COG1473	amidohydrolase
BMD_0597	COG0671	phosphoesterase, PA-phosphatase related
BMD_0598	COG3069	C4-dicarboxylate transmembrane transporter activity
BMD_0599	COG2329	Antibiotic biosynthesis monooxygenase
BMD_0600	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BMD_0601	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BMD_0604	COG1309	transcriptional regulator
BMD_0607	COG2972	Histidine kinase
BMD_0610	COG1234	tRNA 3'-trailer cleavage
BMD_0611	COG0095	Lipoate-protein ligase
BMD_0612	COG0318	PFAM AMP-dependent synthetase and ligase
BMD_0613	COG1024	Enoyl-CoA hydratase
BMD_0636	COG0501	Belongs to the peptidase M48B family
BMD_0637	COG2224	Isocitrate lyase
BMD_0639	COG1506	peptidase
BMD_0639	COG4946	Tricorn protease homolog
BMD_0639	COG0823	Involved in the tonB-independent uptake of proteins
BMD_0640	COG0398	Pfam SNARE associated Golgi protein
BMD_0641	COG1028	Short-chain dehydrogenase reductase Sdr
BMD_0642	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BMD_0643	COG1074	ATP-dependent DNA helicase activity
BMD_0644	COG0420	3'-5' exonuclease activity
BMD_0645	COG0419	ATPase involved in DNA repair
BMD_0646	COG1403	HNH endonuclease
BMD_0653	COG2311	Membrane
BMD_0656	COG0367	asparagine synthase
BMD_0659	COG1562	ergosterol biosynthetic process
BMD_0660	COG1874	Beta-galactosidase
BMD_0660	COG0366	Alpha amylase catalytic
BMD_0661	COG1609	Transcriptional regulator
BMD_0662	COG1012	belongs to the aldehyde dehydrogenase family
BMD_0663	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BMD_0664	COG4187	Peptidase family M20/M25/M40
BMD_0665	COG0833	amino acid
BMD_0666	COG3829	transcription factor binding
BMD_0667	COG1028	Short-chain dehydrogenase reductase Sdr
BMD_0668	COG1666	GTP binding
BMD_0669	COG2996	Protein conserved in bacteria
BMD_0671	COG1307	EDD domain protein, DegV family
BMD_0672	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BMD_0675	COG0561	phosphatase activity
BMD_0676	COG2151	metal-sulfur cluster biosynthetic enzyme
BMD_0677	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BMD_0678	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BMD_0679	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BMD_0680	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BMD_0684	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BMD_0687	COG0542	response to heat
BMD_0689	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BMD_0690	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BMD_0691	COG2084	Dehydrogenase
BMD_0693	COG2267	carboxylic ester hydrolase activity
BMD_0696	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BMD_0697	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BMD_0698	COG5504	Zn-dependent protease
BMD_0699	COG0444	Belongs to the ABC transporter superfamily
BMD_0700	COG4608	Belongs to the ABC transporter superfamily
BMD_0702	COG0601	transmembrane transport
BMD_0705	COG0180	Tryptophanyl-tRNA synthetase
BMD_0706	COG4166	transmembrane transport
BMD_0707	COG0601	transmembrane transport
BMD_0708	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BMD_0710	COG4608	Belongs to the ABC transporter superfamily
BMD_0711	COG0456	acetyltransferase
BMD_0712	COG1113	amino acid transport
BMD_0713	COG0531	amino acid
BMD_0714	COG1393	Belongs to the ArsC family
BMD_0715	COG0583	DNA-binding transcription factor activity
BMD_0718	COG0861	Integral membrane protein TerC family
BMD_0720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BMD_0722	COG1164	Oligoendopeptidase f
BMD_0725	COG2346	COG2346, Truncated hemoglobins
BMD_0726	COG0741	lytic transglycosylase activity
BMD_0727	COG4116	CYTH
BMD_0729	COG2357	RelA SpoT domain protein
BMD_0730	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BMD_0731	COG0564	pseudouridine synthase activity
BMD_0732	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BMD_0733	COG2239	Acts as a magnesium transporter
BMD_0734	COG0475	glutathione-regulated potassium exporter activity
BMD_0734	COG0569	domain protein
BMD_0743	COG0210	DNA helicase
BMD_0745	COG2323	membrane
BMD_0746	COG2153	protein acetylation
BMD_0748	COG2382	esterase
BMD_0750	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BMD_0752	COG1737	Transcriptional regulator
BMD_0753	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BMD_0754	COG1070	Carbohydrate kinase
BMD_0755	COG1953	Uracil, thiamine, allantoin
BMD_0759	COG1522	sequence-specific DNA binding
BMD_0761	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BMD_0764	COG3142	Participates in the control of copper homeostasis
BMD_0765	COG1113	amino acid transport
BMD_0767	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BMD_0768	COG1309	transcriptional regulator
BMD_0769	COG3711	transcriptional antiterminator
BMD_0769	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BMD_0770	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BMD_0771	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BMD_0772	COG1447	Phosphotransferase system cellobiose-specific component IIA
BMD_0773	COG1486	melibiose metabolic process
BMD_0774	COG3275	phosphorelay sensor kinase activity
BMD_0775	COG3279	Response regulator of the LytR AlgR family
BMD_0777	COG1346	cytolysis
BMD_0778	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BMD_0779	COG0243	molybdopterin cofactor binding
BMD_0780	COG2223	nitrite transmembrane transporter activity
BMD_0781	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BMD_0784	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BMD_0789	COG3527	Alpha-acetolactate decarboxylase
BMD_0790	COG0028	Belongs to the TPP enzyme family
BMD_0791	COG4895	conserved protein (DUF2196)
BMD_0793	COG1733	regulation of RNA biosynthetic process
BMD_0794	COG2814	Major facilitator Superfamily
BMD_0795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BMD_0799	COG3052	prosthetic group binding
BMD_0802	COG0784	Response regulator, receiver
BMD_0803	COG4191	Histidine kinase
BMD_0804	COG2066	Belongs to the glutaminase family
BMD_0805	COG1115	amino acid carrier protein
BMD_0806	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BMD_0808	COG4297	protein containing double-stranded beta helix domain
BMD_0809	COG0531	amino acid
BMD_0811	COG1607	acyl-coa hydrolase
BMD_0812	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BMD_0815	COG0390	transport system, permease component
BMD_0816	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BMD_0819	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BMD_0820	COG1136	(ABC) transporter
BMD_0821	COG0577	efflux transmembrane transporter activity
BMD_0823	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BMD_0826	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BMD_0827	COG0833	amino acid
BMD_0829	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BMD_0830	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BMD_0832	COG0861	Integral membrane protein TerC family
BMD_0833	COG1301	dicarboxylic acid transport
BMD_0834	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BMD_0835	COG3290	protein histidine kinase activity
BMD_0843	COG1476	TRANSCRIPTIONal
BMD_0845	COG1368	sulfuric ester hydrolase activity
BMD_0848	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BMD_0849	COG2040	homocysteine
BMD_0850	COG0179	Fumarylacetoacetate (FAA) hydrolase
BMD_0852	COG2851	Citrate transporter
BMD_0853	COG3290	protein histidine kinase activity
BMD_0854	COG4565	transcriptional regulatory protein
BMD_0855	COG3181	Tripartite tricarboxylate transporter family receptor
BMD_0856	COG0583	DNA-binding transcription factor activity
BMD_0857	COG3180	Ammonia monooxygenase
BMD_0858	COG2226	methyltransferase
BMD_0859	COG4176	ABC-type proline glycine betaine transport system permease component
BMD_0860	COG0517	IMP dehydrogenase activity
BMD_0860	COG4175	Glycine betaine
BMD_0861	COG2113	Glycine betaine
BMD_0862	COG1309	transcriptional regulator
BMD_0866	COG0531	amino acid
BMD_0867	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BMD_0870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BMD_0872	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BMD_0873	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BMD_0874	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BMD_0881	COG1737	Transcriptional regulator
BMD_0882	COG1263	PTS System
BMD_0882	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BMD_0884	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BMD_0885	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BMD_0886	COG1116	anion transmembrane transporter activity
BMD_0887	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BMD_0888	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BMD_0890	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BMD_0891	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BMD_0892	COG1733	regulation of RNA biosynthetic process
BMD_0899	COG1511	domain protein
BMD_0900	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BMD_0901	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BMD_0902	COG1733	regulation of RNA biosynthetic process
BMD_0905	COG1132	(ABC) transporter
BMD_0906	COG1132	(ABC) transporter
BMD_0908	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BMD_0909	COG3162	membrane
BMD_0911	COG1414	Transcriptional regulator
BMD_0912	COG0656	L-ascorbic acid biosynthetic process
BMD_0913	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BMD_0915	COG1846	Transcriptional regulator
BMD_0916	COG1566	PFAM secretion protein HlyD family protein
BMD_0917	COG2814	Major facilitator Superfamily
BMD_0918	COG0655	NAD(P)H dehydrogenase (quinone) activity
BMD_0921	COG1609	Transcriptional regulator
BMD_0922	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BMD_0924	COG1129	ABC transporter
BMD_0925	COG1172	Belongs to the binding-protein-dependent transport system permease family
BMD_0926	COG1879	ABC-type sugar transport system periplasmic component
BMD_0927	COG3583	domain protein
BMD_0927	COG3584	3D domain protein
BMD_0928	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BMD_0930	COG1653	transport
BMD_0935	COG3706	GGDEF domain
BMD_0935	COG0745	RESPONSE REGULATOR receiver
BMD_0940	COG0745	RESPONSE REGULATOR receiver
BMD_0941	COG5002	protein histidine kinase activity
BMD_0948	COG0402	S-adenosylhomocysteine deaminase activity
BMD_0949	COG2252	PERMEase
BMD_0952	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BMD_0953	COG1012	belongs to the aldehyde dehydrogenase family
BMD_0955	COG0710	3-dehydroquinate dehydratase activity
BMD_0957	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BMD_0957	COG1263	PTS System
BMD_0958	COG0366	Alpha amylase catalytic
BMD_0959	COG2188	Transcriptional regulator
BMD_0960	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BMD_0961	COG1984	allophanate hydrolase subunit 2
BMD_0962	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BMD_0963	COG1914	H( )-stimulated, divalent metal cation uptake system
BMD_0964	COG1272	protein, Hemolysin III
BMD_0969	COG0778	Nitroreductase
BMD_0970	COG0628	permease
BMD_0975	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BMD_0976	COG2271	Major facilitator Superfamily
BMD_0977	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BMD_0978	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BMD_0979	COG1012	belongs to the aldehyde dehydrogenase family
BMD_0982	COG0439	Biotin carboxylase
BMD_0985	COG0531	amino acid
BMD_0986	COG0402	S-adenosylhomocysteine deaminase activity
BMD_0987	COG1278	Cold shock
BMD_0988	COG2910	NAD(P)H-binding
BMD_0989	COG0673	inositol 2-dehydrogenase activity
BMD_0990	COG0450	alkyl hydroperoxide reductase
BMD_0991	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BMD_0996	COG5001	Diguanylate cyclase
BMD_0996	COG4251	negative regulation of phosphorylation
BMD_0996	COG3706	GGDEF domain
BMD_0996	COG2203	Gaf domain
BMD_0997	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BMD_0998	COG2076	Multidrug Resistance protein
BMD_0999	COG2076	Multidrug Resistance protein
BMD_1015	COG1649	PFAM Uncharacterised BCR, COG1649
BMD_1016	COG1737	Transcriptional regulator
BMD_1020	COG1486	melibiose metabolic process
BMD_1022	COG1447	Phosphotransferase system cellobiose-specific component IIA
BMD_1024	COG2971	BadF BadG BcrA BcrD
BMD_1025	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BMD_1026	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BMD_1027	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BMD_1029	COG3037	sugar-specific permease SgaT UlaA
BMD_1030	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BMD_1030	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BMD_1032	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BMD_1035	COG1376	ErfK ybiS ycfS ynhG family protein
BMD_1037	COG2226	methyltransferase
BMD_1038	COG0583	DNA-binding transcription factor activity
BMD_1041	COG0667	Aldo Keto reductase
BMD_1044	COG0154	amidase activity
BMD_1046	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BMD_1050	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BMD_1052	COG1733	regulation of RNA biosynthetic process
BMD_1055	COG0385	Bile acid
BMD_1057	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BMD_1060	COG4191	Histidine kinase
BMD_1061	COG0784	Response regulator, receiver
BMD_1065	COG0791	NLP P60 protein
BMD_1065	COG1388	LysM domain
BMD_1067	COG2385	sporulation resulting in formation of a cellular spore
BMD_1068	COG0656	L-ascorbic acid biosynthetic process
BMD_1071	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BMD_1072	COG4948	Mandelate Racemase Muconate Lactonizing
BMD_1078	COG0477	Major facilitator Superfamily
BMD_1080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BMD_1082	COG0640	Transcriptional regulator
BMD_1083	COG5658	integral membrane protein
BMD_1088	COG3300	MHYT domain
BMD_1088	COG5001	Diguanylate cyclase
BMD_1089	COG0302	gtp cyclohydrolase
BMD_1094	COG2843	Capsule synthesis protein
BMD_1105	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BMD_1106	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BMD_1110	COG1132	(ABC) transporter
BMD_1114	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BMD_1115	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BMD_1117	COG1216	Glycosyl transferase, family 2
BMD_1117	COG1442	glycosyl transferase family 8
BMD_1120	COG0438	transferase activity, transferring glycosyl groups
BMD_1122	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BMD_1123	COG3944	biosynthesis protein
BMD_1124	COG0489	protein tyrosine kinase activity
BMD_1125	COG4464	protein tyrosine phosphatase activity
BMD_1126	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BMD_1129	COG4464	protein tyrosine phosphatase activity
BMD_1131	COG0028	Belongs to the TPP enzyme family
BMD_1132	COG0069	glutamate synthase activity
BMD_1134	COG2084	Dehydrogenase
BMD_1140	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BMD_1141	COG2146	nitrite reductase [NAD(P)H] activity
BMD_1143	COG2116	formate transmembrane transporter activity
BMD_1144	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BMD_1145	COG4975	Glucose uptake
BMD_1148	COG0534	Mate efflux family protein
BMD_1150	COG1316	TRANSCRIPTIONal
BMD_1152	COG0598	Magnesium transport protein CorA
BMD_1153	COG1404	Belongs to the peptidase S8 family
BMD_1157	COG4821	SIS domain
BMD_1159	COG0363	glucosamine-6-phosphate deaminase activity
BMD_1160	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BMD_1161	COG2190	(PTS) system
BMD_1161	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BMD_1161	COG1263	PTS System
BMD_1162	COG1811	Na channel or pump
BMD_1169	COG1131	(ABC) transporter
BMD_1170	COG1253	flavin adenine dinucleotide binding
BMD_1171	COG0789	Transcriptional regulator
BMD_1173	COG0346	lactoylglutathione lyase activity
BMD_1174	COG2105	PFAM AIG2 family protein
BMD_1174	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BMD_1187	COG4187	Peptidase family M20/M25/M40
BMD_1190	COG0456	acetyltransferase
BMD_1190	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BMD_1193	COG2252	PERMEase
BMD_1195	COG3279	Response regulator of the LytR AlgR family
BMD_1196	COG4555	ABC transporter
BMD_1197	COG1668	transmembrane transport
BMD_1199	COG0789	Transcriptional regulator
BMD_1200	COG1846	Transcriptional regulator
BMD_1201	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BMD_1201	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BMD_1205	COG1785	Belongs to the alkaline phosphatase family
BMD_1206	COG3279	Response regulator of the LytR AlgR family
BMD_1207	COG2205	protein histidine kinase activity
BMD_1207	COG0784	Response regulator, receiver
BMD_1208	COG0861	Integral membrane protein TerC family
BMD_1209	COG1191	sigma factor activity
BMD_1216	COG3243	poly(R)-hydroxyalkanoic acid synthase
BMD_1217	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BMD_1221	COG2186	Transcriptional regulator
BMD_1222	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BMD_1224	COG0247	lactate metabolic process
BMD_1225	COG1139	Iron-sulfur cluster binding protein
BMD_1226	COG1556	Lactate utilization protein
BMD_1227	COG5002	protein histidine kinase activity
BMD_1228	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BMD_1230	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BMD_1231	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BMD_1232	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BMD_1233	COG0436	Aminotransferase
BMD_1234	COG1850	ribulose-bisphosphate carboxylase activity
BMD_1235	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BMD_1236	COG0235	Class ii aldolase
BMD_1237	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BMD_1239	COG1129	ABC transporter
BMD_1240	COG1172	Belongs to the binding-protein-dependent transport system permease family
BMD_1245	COG1846	Transcriptional regulator
BMD_1247	COG4191	Histidine kinase
BMD_1249	COG0542	response to heat
BMD_1253	COG0300	oxidoreductase activity
BMD_1255	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BMD_1256	COG0720	synthase
BMD_1258	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BMD_1259	COG0702	epimerase
BMD_1261	COG4873	Protein conserved in bacteria
BMD_1265	COG3773	Cell wall hydrolase
BMD_1273	COG1410	methionine synthase
BMD_1273	COG0646	methionine synthase
BMD_1274	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BMD_1274	COG0646	methionine synthase
BMD_1275	COG3949	Membrane
BMD_1277	COG0307	riboflavin synthase, alpha
BMD_1279	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BMD_1281	COG3711	transcriptional antiterminator
BMD_1282	COG2190	(PTS) system
BMD_1282	COG1263	PTS System
BMD_1282	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BMD_1285	COG1346	cytolysis
BMD_1287	COG0583	DNA-binding transcription factor activity
BMD_1289	COG0456	acetyltransferase
BMD_1290	COG1028	Short-chain dehydrogenase reductase Sdr
BMD_1291	COG0778	Nitroreductase
BMD_1292	COG0436	Aminotransferase
BMD_1296	COG0784	Response regulator, receiver
BMD_1296	COG0835	chemotaxis
BMD_1298	COG1376	ErfK ybiS ycfS ynhG family protein
BMD_1302	COG1408	metallophosphoesterase
BMD_1303	COG1028	Short-chain dehydrogenase reductase Sdr
BMD_1304	COG2200	EAL domain
BMD_1307	COG4703	Protein of unknown function (DUF1797)
BMD_1308	COG0517	IMP dehydrogenase activity
BMD_1309	COG0583	DNA-binding transcription factor activity
BMD_1310	COG2171	N-acyltransferase activity
BMD_1311	COG1473	amidohydrolase
BMD_1313	COG0668	transmembrane transport
BMD_1314	COG0450	alkyl hydroperoxide reductase
BMD_1315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BMD_1316	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BMD_1317	COG1132	(ABC) transporter
BMD_1318	COG1132	(ABC) transporter
BMD_1319	COG0569	domain protein
BMD_1320	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BMD_1322	COG0561	phosphatase activity
BMD_1327	COG0022	dehydrogenase e1 component
BMD_1328	COG0508	dehydrogenase complex catalyzes the overall conversion of
BMD_1331	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BMD_1333	COG1982	Orn Lys Arg decarboxylase major
BMD_1334	COG4476	Belongs to the UPF0223 family
BMD_1336	COG4493	Belongs to the UPF0637 family
BMD_1338	COG0483	inositol monophosphate 1-phosphatase activity
BMD_1343	COG4896	Protein conserved in bacteria
BMD_1346	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BMD_1347	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BMD_1348	COG4838	Belongs to the UPF0358 family
BMD_1349	COG0772	Belongs to the SEDS family
BMD_1350	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BMD_1351	COG1612	heme a metabolic process
BMD_1352	COG0109	protoheme IX farnesyltransferase activity
BMD_1357	COG3336	cytochrome c oxidase
BMD_1359	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BMD_1360	COG2340	Cysteine-rich secretory protein family
BMD_1362	COG2738	Putative neutral zinc metallopeptidase
BMD_1363	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BMD_1364	COG1694	Mazg nucleotide pyrophosphohydrolase
BMD_1365	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BMD_1366	COG1803	Methylglyoxal synthase
BMD_1367	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BMD_1368	COG0438	transferase activity, transferring glycosyl groups
BMD_1369	COG0617	tRNA 3'-terminal CCA addition
BMD_1370	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BMD_1370	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BMD_1372	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BMD_1373	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BMD_1374	COG1199	ATP-dependent helicase activity
BMD_1374	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BMD_1378	COG0436	Aminotransferase
BMD_1379	COG0017	Asparaginyl-tRNA synthetase
BMD_1380	COG3935	DnaD domain protein
BMD_1381	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BMD_1383	COG4499	WXG100 protein secretion system (Wss), protein YukC
BMD_1383	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BMD_1384	COG3331	DNA recombination
BMD_1393	COG5337	Spore coat protein CotH
BMD_1396	COG0626	cystathionine gamma-synthase activity
BMD_1397	COG0626	cystathionine gamma-synthase activity
BMD_1404	COG1278	Cold shock
BMD_1407	COG3706	GGDEF domain
BMD_1409	COG1111	helicase
BMD_1409	COG1205	dead DEAH box helicase
BMD_1410	COG3359	exonuclease
BMD_1412	COG4474	Belongs to the UPF0398 family
BMD_1414	COG3599	regulation of cell shape
BMD_1419	COG2197	response regulator
BMD_1420	COG0366	Alpha amylase catalytic
BMD_1421	COG0116	Belongs to the methyltransferase superfamily
BMD_1426	COG1175	transmembrane transport
BMD_1428	COG3842	ATPase activity
BMD_1430	COG1199	ATP-dependent helicase activity
BMD_1431	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BMD_1432	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BMD_1433	COG2233	PERMEase
BMD_1434	COG0583	DNA-binding transcription factor activity
BMD_1435	COG1012	belongs to the aldehyde dehydrogenase family
BMD_1438	COG3424	synthase
BMD_1439	COG1755	Isoprenylcysteine carboxyl methyltransferase
BMD_1440	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BMD_1441	COG3541	Predicted nucleotidyltransferase
BMD_1446	COG0328	RNA-DNA hybrid ribonuclease activity
BMD_1447	COG0328	RNA-DNA hybrid ribonuclease activity
BMD_1452	COG2814	Major facilitator Superfamily
BMD_1454	COG2233	PERMEase
BMD_1456	COG2362	D-Aminopeptidase
BMD_1457	COG0601	transmembrane transport
BMD_1458	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BMD_1460	COG4166	transmembrane transport
BMD_1461	COG1619	proteins homologs of microcin C7 resistance protein MccF
BMD_1462	COG0791	NLP P60 protein
BMD_1463	COG4608	Belongs to the ABC transporter superfamily
BMD_1467	COG5001	Diguanylate cyclase
BMD_1467	COG3300	MHYT domain
BMD_1472	COG2197	response regulator
BMD_1473	COG4585	Histidine kinase
BMD_1474	COG3239	Fatty acid desaturase
BMD_1475	COG2205	protein histidine kinase activity
BMD_1477	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BMD_1480	COG1388	LysM domain
BMD_1480	COG0791	NLP P60 protein
BMD_1481	COG1819	glycosyl
BMD_1482	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BMD_1484	COG2814	Major facilitator Superfamily
BMD_1486	COG1028	Short-chain dehydrogenase reductase Sdr
BMD_1487	COG3964	amidohydrolase
BMD_1491	COG2188	Transcriptional regulator
BMD_1493	COG0434	BtpA family
BMD_1494	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BMD_1496	COG1785	Belongs to the alkaline phosphatase family
BMD_1497	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BMD_1498	COG1404	Belongs to the peptidase S8 family
BMD_1500	COG1846	Transcriptional regulator
BMD_1501	COG1566	PFAM secretion protein HlyD family protein
BMD_1502	COG2814	Major facilitator Superfamily
BMD_1507	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BMD_1508	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BMD_1509	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BMD_1510	COG1120	ATPase activity
BMD_1513	COG2814	Major facilitator Superfamily
BMD_1517	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BMD_1518	COG1733	regulation of RNA biosynthetic process
BMD_1519	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BMD_1521	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BMD_1523	COG4175	Glycine betaine
BMD_1523	COG3448	diguanylate cyclase activity
BMD_1526	COG0469	pyruvate kinase activity
BMD_1528	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BMD_1529	COG2208	phosphoserine phosphatase activity
BMD_1531	COG0531	amino acid
BMD_1533	COG1011	Hydrolase
BMD_1534	COG0405	Gamma-glutamyltransferase
BMD_1536	COG1621	beta-fructofuranosidase activity
BMD_1537	COG1621	beta-fructofuranosidase activity
BMD_1538	COG2193	ferroxidase activity
BMD_1539	COG0477	Major facilitator Superfamily
BMD_1540	COG0156	8-amino-7-oxononanoate synthase activity
BMD_1541	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BMD_1543	COG2814	Major facilitator Superfamily
BMD_1546	COG1012	belongs to the aldehyde dehydrogenase family
BMD_1547	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BMD_1550	COG1280	lysine exporter protein (LysE YggA)
BMD_1551	COG1113	amino acid transport
BMD_1554	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BMD_1560	COG1113	amino acid transport
BMD_1564	COG1609	Transcriptional regulator
BMD_1567	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BMD_1568	COG1621	beta-fructofuranosidase activity
BMD_1569	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BMD_1569	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BMD_1570	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BMD_1571	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BMD_1572	COG3715	PTS system
BMD_1573	COG3716	PTS system mannose fructose sorbose family IID component
BMD_1574	COG1621	beta-fructofuranosidase activity
BMD_1575	COG0765	amino acid transport
BMD_1576	COG0765	amino acid transport
BMD_1577	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BMD_1578	COG1464	Belongs to the NlpA lipoprotein family
BMD_1579	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BMD_1580	COG2011	ABC-type metal ion transport system permease component
BMD_1584	COG1464	Belongs to the NlpA lipoprotein family
BMD_1585	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BMD_1586	COG2011	ABC-type metal ion transport system permease component
BMD_1588	COG1464	Belongs to the NlpA lipoprotein family
BMD_1590	COG0024	Methionine aminopeptidase
BMD_1593	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BMD_1595	COG0656	L-ascorbic acid biosynthetic process
BMD_1596	COG2986	histidine ammonia-lyase
BMD_1598	COG1228	amidohydrolase
BMD_1599	COG0010	Belongs to the arginase family
BMD_1600	COG1957	nucleoside hydrolase
BMD_1601	COG0473	3-isopropylmalate dehydrogenase activity
BMD_1602	COG1288	antiporter activity
BMD_1603	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BMD_1612	COG2364	Membrane
BMD_1613	COG1846	Transcriptional regulator
BMD_1614	COG0456	acetyltransferase
BMD_1615	COG0640	Transcriptional regulator
BMD_1625	COG0791	NLP P60 protein
BMD_1625	COG1388	LysM domain
BMD_1629	COG2318	DinB family
BMD_1634	COG0583	DNA-binding transcription factor activity
BMD_1639	COG1028	Short-chain dehydrogenase reductase Sdr
BMD_1641	COG3850	Histidine kinase
BMD_1641	COG5002	protein histidine kinase activity
BMD_1642	COG0745	RESPONSE REGULATOR receiver
BMD_1643	COG0586	Pfam SNARE associated Golgi protein
BMD_1645	COG0726	polysaccharide deacetylase
BMD_1649	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BMD_1651	COG0697	spore germination
BMD_1652	COG0387	Pfam Sodium calcium exchanger
BMD_1658	COG2610	gluconate transmembrane transporter activity
BMD_1660	COG1250	3-hydroxyacyl-CoA dehydrogenase
BMD_1661	COG0697	spore germination
BMD_1662	COG0583	DNA-binding transcription factor activity
BMD_1665	COG1309	transcriptional regulator
BMD_1666	COG0861	Integral membrane protein TerC family
BMD_1668	COG5577	PFAM Coat F domain
BMD_1670	COG1366	Belongs to the anti-sigma-factor antagonist family
BMD_1671	COG1522	sequence-specific DNA binding
BMD_1672	COG3813	Protein conserved in bacteria
BMD_1679	COG2076	Multidrug Resistance protein
BMD_1682	COG1278	Cold shock
BMD_1683	COG0028	Belongs to the TPP enzyme family
BMD_1694	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BMD_1695	COG2076	Multidrug Resistance protein
BMD_1697	COG0517	IMP dehydrogenase activity
BMD_1698	COG2323	membrane
BMD_1699	COG2807	transmembrane transport
BMD_1700	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BMD_1701	COG0583	DNA-binding transcription factor activity
BMD_1702	COG0747	negative chemotaxis
BMD_1703	COG0601	transmembrane transport
BMD_1704	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BMD_1705	COG0444	Belongs to the ABC transporter superfamily
BMD_1706	COG4608	Belongs to the ABC transporter superfamily
BMD_1707	COG0534	Mate efflux family protein
BMD_1710	COG2172	sigma factor antagonist activity
BMD_1712	COG0477	Major facilitator Superfamily
BMD_1713	COG3858	chitin binding
BMD_1713	COG1388	LysM domain
BMD_1714	COG1376	ErfK ybiS ycfS ynhG family protein
BMD_1719	COG2226	methyltransferase
BMD_1720	COG1733	regulation of RNA biosynthetic process
BMD_1721	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BMD_1724	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BMD_1725	COG3420	alginic acid biosynthetic process
BMD_1730	COG1278	Cold shock
BMD_1741	COG1113	amino acid transport
BMD_1742	COG2318	DinB family
BMD_1747	COG0697	spore germination
BMD_1749	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BMD_1750	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BMD_1751	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BMD_1754	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BMD_1755	COG0789	Transcriptional regulator
BMD_1757	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BMD_1758	COG0531	amino acid
BMD_1759	COG3223	Belongs to the PsiE family
BMD_1761	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BMD_1762	COG1366	Belongs to the anti-sigma-factor antagonist family
BMD_1763	COG3850	Histidine kinase
BMD_1763	COG5002	protein histidine kinase activity
BMD_1764	COG0745	RESPONSE REGULATOR receiver
BMD_1766	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BMD_1768	COG0833	amino acid
BMD_1770	COG2986	histidine ammonia-lyase
BMD_1772	COG1228	amidohydrolase
BMD_1773	COG0010	Belongs to the arginase family
BMD_1774	COG2271	Major facilitator Superfamily
BMD_1775	COG1994	Peptidase M50
BMD_1776	COG2261	transglycosylase associated protein
BMD_1778	COG1027	Aspartate ammonia-lyase
BMD_1779	COG5577	PFAM Coat F domain
BMD_1782	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BMD_1783	COG1366	Belongs to the anti-sigma-factor antagonist family
BMD_1784	COG2135	peptidase activity
BMD_1785	COG2135	peptidase activity
BMD_1788	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BMD_1800	COG0517	IMP dehydrogenase activity
BMD_1801	COG0011	TIGRFAM Protein of
BMD_1802	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BMD_1805	COG1366	Belongs to the anti-sigma-factor antagonist family
BMD_1806	COG1366	Belongs to the anti-sigma-factor antagonist family
BMD_1808	COG4549	nuclear export factor GLE1
BMD_1809	COG3689	TIGRFAM TIGR03943 family protein
BMD_1810	COG0701	Predicted permease
BMD_1813	COG0701	Predicted permease
BMD_1817	COG2217	Heavy metal translocating P-type atpase
BMD_1820	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BMD_1825	COG1114	Component of the transport system for branched-chain amino acids
BMD_1826	COG0667	Aldo Keto reductase
BMD_1827	COG4282	regulation of fungal-type cell wall biogenesis
BMD_1830	COG3848	Pyruvate phosphate dikinase
BMD_1830	COG0574	Belongs to the PEP-utilizing enzyme family
BMD_1831	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BMD_1833	COG0601	transmembrane transport
BMD_1835	COG0444	Belongs to the ABC transporter superfamily
BMD_1836	COG4608	Belongs to the ABC transporter superfamily
BMD_1838	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BMD_1840	COG0477	Major facilitator Superfamily
BMD_1844	COG1012	belongs to the aldehyde dehydrogenase family
BMD_1852	COG0517	IMP dehydrogenase activity
BMD_1856	COG1309	transcriptional regulator
BMD_1859	COG1070	Carbohydrate kinase
BMD_1860	COG0477	Major facilitator Superfamily
BMD_1860	COG2814	Major facilitator Superfamily
BMD_1862	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BMD_1863	COG1845	cytochrome c oxidase, subunit III
BMD_1865	COG0589	response to stress
BMD_1866	COG1028	Short-chain dehydrogenase reductase Sdr
BMD_1867	COG1612	heme a metabolic process
BMD_1868	COG2072	flavoprotein involved in K transport
BMD_1870	COG2252	PERMEase
BMD_1871	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BMD_1872	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BMD_1873	COG0022	dehydrogenase e1 component
BMD_1874	COG0508	dehydrogenase complex catalyzes the overall conversion of
BMD_1875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BMD_1876	COG3284	Transcriptional regulator
BMD_1877	COG1063	alcohol dehydrogenase
BMD_1878	COG0626	cystathionine gamma-synthase activity
BMD_1879	COG1846	Transcriptional regulator
BMD_1884	COG0628	permease
BMD_1885	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BMD_1887	COG2211	Major facilitator Superfamily
BMD_1891	COG0589	response to stress
BMD_1892	COG5002	protein histidine kinase activity
BMD_1894	COG1937	Protein conserved in bacteria
BMD_1895	COG2608	mercury ion transmembrane transporter activity
BMD_1896	COG2217	Heavy metal translocating P-type atpase
BMD_1898	COG1388	LysM domain
BMD_1899	COG2271	Major facilitator Superfamily
BMD_1905	COG0640	Transcriptional regulator
BMD_1906	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BMD_1908	COG2050	protein possibly involved in aromatic compounds catabolism
BMD_1909	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BMD_1910	COG2323	membrane
BMD_1913	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BMD_1914	COG1802	Transcriptional regulator
BMD_1915	COG0473	3-isopropylmalate dehydrogenase activity
BMD_1916	COG2814	Major facilitator Superfamily
BMD_1917	COG1733	regulation of RNA biosynthetic process
BMD_1918	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BMD_1918	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BMD_1919	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BMD_1919	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BMD_1924	COG2264	protein methyltransferase activity
BMD_1926	COG5566	PFAM Mor transcription activator
BMD_1929	COG0561	phosphatase activity
BMD_1930	COG1876	peptidase activity
BMD_1932	COG0726	polysaccharide deacetylase
BMD_1937	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BMD_1940	COG0386	Belongs to the glutathione peroxidase family
BMD_1941	COG1418	mRNA catabolic process
BMD_1942	COG0488	(ABC) transporter
BMD_1943	COG1413	lyase activity
BMD_1944	COG0726	polysaccharide deacetylase
BMD_1946	COG2521	methyltransferase
BMD_1946	COG2136	Putative SAM-dependent methyltransferase
BMD_1948	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BMD_1949	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BMD_1951	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BMD_1954	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BMD_1955	COG0406	alpha-ribazole phosphatase activity
BMD_1957	COG2096	Adenosyltransferase
BMD_1958	COG2962	Rard protein
BMD_1962	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BMD_1963	COG0322	excinuclease ABC activity
BMD_1965	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BMD_1966	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BMD_1967	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BMD_1969	COG3011	Protein conserved in bacteria
BMD_1970	COG1595	DNA-templated transcription, initiation
BMD_1974	COG2002	toxin-antitoxin pair type II binding
BMD_1975	COG0534	Mate efflux family protein
BMD_1976	COG1028	Short-chain dehydrogenase reductase Sdr
BMD_1981	COG1368	sulfuric ester hydrolase activity
BMD_1983	COG3853	Toxic anion resistance protein (TelA)
BMD_1987	COG0726	polysaccharide deacetylase
BMD_1989	COG2234	aminopeptidase activity
BMD_1990	COG5002	protein histidine kinase activity
BMD_1992	COG1823	symporter activity
BMD_1993	COG1523	belongs to the glycosyl hydrolase 13 family
BMD_1994	COG1012	belongs to the aldehyde dehydrogenase family
BMD_1995	COG2124	cytochrome p450
BMD_1995	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BMD_1996	COG2112	serine threonine protein kinase
BMD_1998	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BMD_1999	COG1360	Flagellar Motor Protein
BMD_2002	COG3361	conserved protein (COG2071)
BMD_2003	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BMD_2004	COG1757	Na H antiporter
BMD_2006	COG0833	amino acid
BMD_2007	COG3594	Acyltransferase
BMD_2008	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BMD_2009	COG0745	RESPONSE REGULATOR receiver
BMD_2010	COG5002	protein histidine kinase activity
BMD_2011	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BMD_2012	COG3104	oligopeptide transport
BMD_2014	COG0281	malic enzyme
BMD_2015	COG3493	citrate carrier protein
BMD_2016	COG0561	phosphatase activity
BMD_2017	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BMD_2020	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BMD_2021	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BMD_2022	COG0765	amino acid transport
BMD_2023	COG0765	amino acid transport
BMD_2024	COG1126	abc transporter atp-binding protein
BMD_2025	COG0196	riboflavin kinase activity
BMD_2026	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BMD_2028	COG0860	N-Acetylmuramoyl-L-alanine amidase
BMD_2036	COG1611	Belongs to the LOG family
BMD_2037	COG0281	malic enzyme
BMD_2038	COG3402	PFAM membrane-flanked domain
BMD_2039	COG3428	Bacterial PH domain
BMD_2041	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BMD_2042	COG0109	protoheme IX farnesyltransferase activity
BMD_2043	COG4195	phage-related replication protein
BMD_2047	COG0789	Transcriptional regulator
BMD_2054	COG0583	DNA-binding transcription factor activity
BMD_2055	COG0070	glutamate synthase
BMD_2055	COG0069	glutamate synthase activity
BMD_2055	COG0067	glutamate synthase
BMD_2056	COG0493	'glutamate synthase
BMD_2060	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BMD_2062	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BMD_2064	COG1846	Transcriptional regulator
BMD_2065	COG1380	Effector of murein hydrolase LrgA
BMD_2066	COG1346	cytolysis
BMD_2067	COG1366	Belongs to the anti-sigma-factor antagonist family
BMD_2070	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BMD_2071	COG0463	Glycosyl transferase, family 2
BMD_2072	COG2246	polysaccharide biosynthetic process
BMD_2073	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BMD_2074	COG0745	RESPONSE REGULATOR receiver
BMD_2076	COG5583	Uncharacterized small protein (DUF2292)
BMD_2078	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BMD_2080	COG4208	sulfate ABC transporter
BMD_2083	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BMD_2086	COG1349	DNA-binding transcription factor activity
BMD_2087	COG1105	Belongs to the carbohydrate kinase PfkB family
BMD_2088	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BMD_2088	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BMD_2088	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BMD_2089	COG0527	aspartate kinase activity
BMD_2091	COG2032	superoxide dismutase activity
BMD_2092	COG1233	COG1233 Phytoene dehydrogenase and related
BMD_2094	COG0300	oxidoreductase activity
BMD_2095	COG0640	Transcriptional regulator
BMD_2096	COG1012	belongs to the aldehyde dehydrogenase family
BMD_2097	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BMD_2100	COG0733	neurotransmitter:sodium symporter activity
BMD_2101	COG3773	Cell wall hydrolase
BMD_2105	COG0673	inositol 2-dehydrogenase activity
BMD_2106	COG1082	Xylose isomerase domain protein TIM barrel
BMD_2107	COG2094	Belongs to the DNA glycosylase MPG family
BMD_2109	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BMD_2110	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BMD_2112	COG0454	-acetyltransferase
BMD_2114	COG2814	Major facilitator Superfamily
BMD_2117	COG3871	stress protein (general stress protein 26)
BMD_2121	COG1595	DNA-templated transcription, initiation
BMD_2123	COG0714	Associated with various cellular activities
BMD_2124	COG4548	von Willebrand factor, type A
BMD_2125	COG0697	spore germination
BMD_2127	COG2207	Transcriptional regulator
BMD_2128	COG1994	Peptidase M50
BMD_2130	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BMD_2131	COG1119	ATPase activity
BMD_2134	COG1657	PFAM Prenyltransferase squalene oxidase
BMD_2136	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BMD_2136	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BMD_2138	COG0384	phenazine biosynthesis protein PhzF
BMD_2141	COG1378	Sugar-specific transcriptional regulator TrmB
BMD_2142	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BMD_2143	COG1028	Short-chain dehydrogenase reductase Sdr
BMD_2147	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BMD_2148	COG1279	arginine transmembrane transporter activity
BMD_2152	COG2814	Major facilitator Superfamily
BMD_2154	COG3541	Predicted nucleotidyltransferase
BMD_2156	COG1396	sequence-specific DNA binding
BMD_2159	COG0494	nUDIX hydrolase
BMD_2160	COG1335	isochorismatase
BMD_2161	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BMD_2162	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BMD_2163	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BMD_2164	COG1098	S1 RNA binding domain
BMD_2165	COG1404	Belongs to the peptidase S8 family
BMD_2166	COG1028	Short-chain dehydrogenase reductase Sdr
BMD_2167	COG1254	Belongs to the acylphosphatase family
BMD_2168	COG2223	nitrite transmembrane transporter activity
BMD_2169	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BMD_2171	COG0662	Cupin 2, conserved barrel domain protein
BMD_2171	COG2207	Transcriptional regulator
BMD_2172	COG0697	spore germination
BMD_2173	COG0488	(ABC) transporter
BMD_2174	COG0697	spore germination
BMD_2175	COG0531	amino acid
BMD_2178	COG1131	(ABC) transporter
BMD_2179	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BMD_2180	COG1757	Na H antiporter
BMD_2182	COG1609	Transcriptional regulator
BMD_2184	COG1533	DNA photolyase activity
BMD_2189	COG0551	DNA topoisomerase type I activity
BMD_2189	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BMD_2191	COG0446	pyridine nucleotide-disulphide oxidoreductase
BMD_2194	COG1063	alcohol dehydrogenase
BMD_2195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BMD_2199	COG1757	Na H antiporter
BMD_2201	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BMD_2203	COG2720	vancomycin resistance protein
BMD_2212	COG0514	ATP-dependent DNA helicase (RecQ)
BMD_2219	COG1575	Belongs to the MenA family. Type 1 subfamily
BMD_2223	COG2814	Major facilitator Superfamily
BMD_2224	COG0583	DNA-binding transcription factor activity
BMD_2225	COG1725	Transcriptional regulator
BMD_2226	COG1131	(ABC) transporter
BMD_2228	COG1595	DNA-templated transcription, initiation
BMD_2231	COG1764	response to oxidative stress
BMD_2232	COG1846	Transcriptional regulator
BMD_2236	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
BMD_2238	COG3584	3D domain protein
BMD_2238	COG1388	LysM domain
BMD_2242	COG5002	protein histidine kinase activity
BMD_2243	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BMD_2244	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BMD_2245	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BMD_2248	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BMD_2251	COG2409	Drug exporters of the RND superfamily
BMD_2252	COG1834	amidinotransferase
BMD_2254	COG1295	ribonuclease BN
BMD_2267	COG0110	maltose O-acetyltransferase activity
BMD_2268	COG0346	lactoylglutathione lyase activity
BMD_2270	COG1366	Belongs to the anti-sigma-factor antagonist family
BMD_2272	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BMD_2275	COG2176	DNA-directed DNA polymerase activity
BMD_2279	COG0114	fumarate hydratase activity
BMD_2281	COG3757	hydrolase, family 25
BMD_2281	COG3409	Peptidoglycan-binding domain 1 protein
BMD_2283	COG5002	protein histidine kinase activity
BMD_2289	COG0778	Nitroreductase
BMD_2291	COG0300	oxidoreductase activity
BMD_2292	COG3290	protein histidine kinase activity
BMD_2293	COG4565	transcriptional regulatory protein
BMD_2294	COG2851	Citrate transporter
BMD_2296	COG2610	gluconate transmembrane transporter activity
BMD_2297	COG1028	Short-chain dehydrogenase reductase Sdr
BMD_2298	COG2195	Cleaves the N-terminal amino acid of tripeptides
BMD_2304	COG0583	DNA-binding transcription factor activity
BMD_2307	COG1301	dicarboxylic acid transport
BMD_2308	COG0019	diaminopimelate decarboxylase activity
BMD_2311	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BMD_2313	COG4191	Histidine kinase
BMD_2316	COG1028	Short-chain dehydrogenase reductase Sdr
BMD_2317	COG0318	PFAM AMP-dependent synthetase and ligase
BMD_2319	COG1250	3-hydroxyacyl-CoA dehydrogenase
BMD_2320	COG1024	Enoyl-CoA hydratase
BMD_2323	COG2045	Belongs to the ComB family
BMD_2324	COG1960	acyl-CoA dehydrogenase activity
BMD_2325	COG1028	Short-chain dehydrogenase reductase Sdr
BMD_2326	COG1024	Enoyl-CoA hydratase
BMD_2329	COG1141	Ferredoxin
BMD_2331	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BMD_2332	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BMD_2333	COG0183	Belongs to the thiolase family
BMD_2334	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BMD_2339	COG1509	lysine 2,3-aminomutase activity
BMD_2341	COG0833	amino acid
BMD_2342	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BMD_2345	COG1979	alcohol dehydrogenase
BMD_2346	COG0738	Major facilitator superfamily
BMD_2347	COG2207	Transcriptional regulator
BMD_2347	COG1917	Cupin 2, conserved barrel domain protein
BMD_2348	COG2249	NAD(P)H dehydrogenase (quinone) activity
BMD_2349	COG1181	Belongs to the D-alanine--D-alanine ligase family
BMD_2353	COG3977	Valine--pyruvate aminotransferase
BMD_2355	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BMD_2356	COG3773	Cell wall hydrolase
BMD_2358	COG3119	arylsulfatase activity
BMD_2359	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BMD_2360	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BMD_2362	COG0531	amino acid
BMD_2363	COG2814	Major facilitator Superfamily
BMD_2364	COG1846	Transcriptional regulator
BMD_2365	COG1033	growth of symbiont in host cell
BMD_2365	COG2409	Drug exporters of the RND superfamily
BMD_2367	COG3842	ATPase activity
BMD_2368	COG2222	sugar isomerase
BMD_2369	COG1653	transport
BMD_2370	COG1175	transmembrane transport
BMD_2371	COG0395	ABC-type sugar transport system, permease component
BMD_2372	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BMD_2373	COG2188	Transcriptional regulator
BMD_2374	COG2202	Pas domain
BMD_2374	COG1366	Belongs to the anti-sigma-factor antagonist family
BMD_2375	COG3832	glyoxalase III activity
BMD_2376	COG0640	Transcriptional regulator
BMD_2378	COG2267	carboxylic ester hydrolase activity
BMD_2380	COG3386	PFAM SMP-30 Gluconolaconase
BMD_2382	COG2368	4-hydroxyphenylacetate
BMD_2383	COG3739	integral membrane protein
BMD_2385	COG0326	Molecular chaperone. Has ATPase activity
BMD_2386	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BMD_2398	COG3223	Belongs to the PsiE family
BMD_2402	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BMD_2403	COG3409	Peptidoglycan-binding domain 1 protein
BMD_2403	COG3757	hydrolase, family 25
BMD_2405	COG0697	spore germination
BMD_2406	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BMD_2410	COG4572	Cation transport regulator
BMD_2411	COG2015	COG2015, Alkyl sulfatase and related hydrolases
BMD_2413	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BMD_2429	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BMD_2432	COG0494	nUDIX hydrolase
BMD_2433	COG0702	epimerase
BMD_2434	COG0318	PFAM AMP-dependent synthetase and ligase
BMD_2435	COG1846	Transcriptional regulator
BMD_2436	COG2720	vancomycin resistance protein
BMD_2437	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BMD_2444	COG0076	glutamate decarboxylase activity
BMD_2450	COG2116	formate transmembrane transporter activity
BMD_2451	COG5609	conserved protein (DUF2294)
BMD_2453	COG2271	Major facilitator Superfamily
BMD_2454	COG0277	FAD linked oxidase domain protein
BMD_2455	COG0840	transmembrane signaling receptor activity
BMD_2458	COG1408	metallophosphoesterase
BMD_2459	COG3663	DNA glycosylase
BMD_2460	COG3883	PFAM NLP P60 protein
BMD_2460	COG0791	NLP P60 protein
BMD_2461	COG1587	Uroporphyrinogen-III synthase
BMD_2462	COG1414	Transcriptional regulator
BMD_2463	COG0439	Biotin carboxylase
BMD_2464	COG0511	ligase activity, forming carbon-carbon bonds
BMD_2465	COG1984	allophanate hydrolase subunit 2
BMD_2466	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BMD_2467	COG4336	lyase activity
BMD_2468	COG1914	H( )-stimulated, divalent metal cation uptake system
BMD_2469	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BMD_2472	COG2814	Major facilitator Superfamily
BMD_2476	COG1366	Belongs to the anti-sigma-factor antagonist family
BMD_2478	COG2249	NAD(P)H dehydrogenase (quinone) activity
BMD_2482	COG0318	PFAM AMP-dependent synthetase and ligase
BMD_2483	COG1268	BioY protein
BMD_2484	COG0183	Belongs to the thiolase family
BMD_2488	COG0431	NADPH-dependent FMN reductase
BMD_2489	COG2197	response regulator
BMD_2490	COG4585	Histidine kinase
BMD_2490	COG2203	Gaf domain
BMD_2494	COG0697	spore germination
BMD_2496	COG2153	protein acetylation
BMD_2497	COG0129	dihydroxy-acid dehydratase activity
BMD_2498	COG2267	carboxylic ester hydrolase activity
BMD_2499	COG1227	inorganic diphosphatase activity
BMD_2502	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BMD_2504	COG0204	Acyl-transferase
BMD_2505	COG2233	PERMEase
BMD_2508	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BMD_2511	COG1914	H( )-stimulated, divalent metal cation uptake system
BMD_2514	COG1846	Transcriptional regulator
BMD_2516	COG4974	Belongs to the 'phage' integrase family
BMD_2520	COG4302	ethanolamine ammonia-lyase activity
BMD_2521	COG4303	Ethanolamine ammonia lyase large subunit
BMD_2525	COG0833	amino acid
BMD_2527	COG1247	-acetyltransferase
BMD_2528	COG1335	isochorismatase
BMD_2530	COG3403	YqcI/YcgG family
BMD_2531	COG1280	lysine exporter protein (LysE YggA)
BMD_2532	COG2267	carboxylic ester hydrolase activity
BMD_2533	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BMD_2534	COG0187	DNA topoisomerase II activity
BMD_2535	COG1832	CoA-binding protein
BMD_2536	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BMD_2538	COG4841	protein insertion into membrane
BMD_2539	COG0824	Thioesterase
BMD_2545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BMD_2546	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BMD_2550	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BMD_2558	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BMD_2559	COG2068	MobA-Related Protein
BMD_2560	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BMD_2572	COG1183	phosphatidylcholine synthase activity
BMD_2574	COG2814	Major facilitator Superfamily
BMD_2575	COG1683	Conserved Protein
BMD_2576	COG1302	Protein conserved in bacteria
BMD_2579	COG1295	ribonuclease BN
BMD_2581	COG2814	Major facilitator Superfamily
BMD_2582	COG2814	Major facilitator Superfamily
BMD_2583	COG0789	Transcriptional regulator
BMD_2585	COG0288	reversible hydration of carbon dioxide
BMD_2586	COG0659	secondary active sulfate transmembrane transporter activity
BMD_2587	COG0745	RESPONSE REGULATOR receiver
BMD_2588	COG5002	protein histidine kinase activity
BMD_2590	COG4282	regulation of fungal-type cell wall biogenesis
BMD_2591	COG0531	amino acid
BMD_2593	COG0860	N-Acetylmuramoyl-L-alanine amidase
BMD_2594	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BMD_2609	COG1363	Peptidase, m42
BMD_2611	COG1114	Component of the transport system for branched-chain amino acids
BMD_2615	COG0004	ammonium transporteR
BMD_2618	COG1252	NADH dehydrogenase
BMD_2619	COG0679	Auxin Efflux Carrier
BMD_2620	COG0281	malic enzyme
BMD_2621	COG1473	amidohydrolase
BMD_2622	COG2271	Major facilitator Superfamily
BMD_2626	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BMD_2627	COG0163	prenyltransferase activity
BMD_2628	COG0583	DNA-binding transcription factor activity
BMD_2629	COG0679	Auxin Efflux Carrier
BMD_2633	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BMD_2634	COG0247	lactate metabolic process
BMD_2635	COG0277	FAD linked oxidase domain protein
BMD_2636	COG3835	regulator
BMD_2637	COG0693	protein deglycase activity
BMD_2639	COG2610	gluconate transmembrane transporter activity
BMD_2643	COG1131	(ABC) transporter
BMD_2645	COG2197	response regulator
BMD_2653	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BMD_2655	COG0586	Pfam SNARE associated Golgi protein
BMD_2656	COG1515	deoxyribonuclease V activity
BMD_2657	COG0584	glycerophosphoryl diester phosphodiesterase
BMD_2658	COG3153	acetyltransferase
BMD_2658	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BMD_2660	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BMD_2661	COG0531	amino acid
BMD_2670	COG5444	nuclease activity
BMD_2674	COG0534	Mate efflux family protein
BMD_2675	COG1566	PFAM secretion protein HlyD family protein
BMD_2677	COG1846	Transcriptional regulator
BMD_2678	COG0708	Exodeoxyribonuclease III
BMD_2681	COG0673	inositol 2-dehydrogenase activity
BMD_2682	COG1349	DNA-binding transcription factor activity
BMD_2683	COG3853	Toxic anion resistance protein (TelA)
BMD_2685	COG2310	stress, protein
BMD_2686	COG2310	stress, protein
BMD_2687	COG2310	stress, protein
BMD_2688	COG0737	Belongs to the 5'-nucleotidase family
BMD_2691	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BMD_2692	COG1131	(ABC) transporter
BMD_2694	COG2084	Dehydrogenase
BMD_2695	COG1278	Cold shock
BMD_2696	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BMD_2697	COG0028	Belongs to the TPP enzyme family
BMD_2698	COG1278	Cold shock
BMD_2704	COG1028	Short-chain dehydrogenase reductase Sdr
BMD_2706	COG0427	acetyl-CoA hydrolase
BMD_2707	COG3279	Response regulator of the LytR AlgR family
BMD_2708	COG2323	membrane
BMD_2709	COG2814	Major facilitator Superfamily
BMD_2710	COG1388	LysM domain
BMD_2710	COG3584	3D domain protein
BMD_2711	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BMD_2719	COG0277	FAD linked oxidase domain protein
BMD_2721	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BMD_2731	COG0579	oxidoreductase
BMD_2737	COG1486	melibiose metabolic process
BMD_2746	COG0596	Alpha beta hydrolase
BMD_2747	COG1929	Belongs to the glycerate kinase type-1 family
BMD_2748	COG2610	gluconate transmembrane transporter activity
BMD_2749	COG3835	regulator
BMD_2750	COG1454	alcohol dehydrogenase
BMD_2751	COG3152	Membrane
BMD_2755	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BMD_2759	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BMD_2760	COG2323	membrane
BMD_2762	COG0672	)-iron permease
BMD_2766	COG2249	NAD(P)H dehydrogenase (quinone) activity
BMD_2771	COG0822	iron-sulfur transferase activity
BMD_2774	COG2072	flavoprotein involved in K transport
BMD_2775	COG0318	PFAM AMP-dependent synthetase and ligase
BMD_2782	COG0531	amino acid
BMD_2783	COG1114	Component of the transport system for branched-chain amino acids
BMD_2784	COG0776	regulation of translation
BMD_2786	COG0531	amino acid
BMD_2791	COG1278	Cold shock
BMD_2792	COG0513	Belongs to the DEAD box helicase family
BMD_2794	COG1278	Cold shock
BMD_2796	COG0346	lactoylglutathione lyase activity
BMD_2800	COG2271	Major facilitator Superfamily
BMD_2801	COG1846	Transcriptional regulator
BMD_2801	COG0456	acetyltransferase
BMD_2803	COG0697	spore germination
BMD_2806	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BMD_2807	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BMD_2812	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BMD_2813	COG0295	cytidine deaminase activity
BMD_2814	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BMD_2817	COG2390	Transcriptional regulator
BMD_2823	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BMD_2825	COG1695	Transcriptional regulator
BMD_2826	COG0501	Belongs to the peptidase M48B family
BMD_2827	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BMD_2828	COG1742	UPF0060 membrane protein
BMD_2833	COG2031	fatty acid transporter
BMD_2838	COG2391	methyltransferase activity
BMD_2839	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BMD_2841	COG1979	alcohol dehydrogenase
BMD_2842	COG0583	DNA-binding transcription factor activity
BMD_2845	COG0456	acetyltransferase
BMD_2845	COG1214	PFAM Peptidase M22, glycoprotease
BMD_2846	COG2211	Major facilitator Superfamily
BMD_2852	COG1028	Short-chain dehydrogenase reductase Sdr
BMD_2853	COG1063	alcohol dehydrogenase
BMD_2858	COG0025	NhaP-type Na H and K H
BMD_2859	COG1253	flavin adenine dinucleotide binding
BMD_2864	COG4608	Belongs to the ABC transporter superfamily
BMD_2866	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BMD_2867	COG0601	transmembrane transport
BMD_2868	COG0747	negative chemotaxis
BMD_2870	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BMD_2874	COG1525	nuclease
BMD_2876	COG0579	oxidoreductase
BMD_2877	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BMD_2878	COG0561	phosphatase activity
BMD_2887	COG2309	aminopeptidase activity
BMD_2888	COG1414	Transcriptional regulator
BMD_2889	COG0179	Fumarylacetoacetate (FAA) hydrolase
BMD_2890	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BMD_2891	COG0277	FAD linked oxidase domain protein
BMD_2892	COG0247	lactate metabolic process
BMD_2893	COG0277	FAD linked oxidase domain protein
BMD_2894	COG1620	l-lactate permease
BMD_2899	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BMD_2900	COG1131	(ABC) transporter
BMD_2904	COG1595	DNA-templated transcription, initiation
BMD_2909	COG4682	membrane
BMD_2912	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BMD_2913	COG1366	Belongs to the anti-sigma-factor antagonist family
BMD_2916	COG2323	membrane
BMD_2917	COG1876	peptidase activity
BMD_2920	COG5002	protein histidine kinase activity
BMD_2921	COG0745	RESPONSE REGULATOR receiver
BMD_2925	COG0508	dehydrogenase complex catalyzes the overall conversion of
BMD_2926	COG0567	Dehydrogenase, E1 component
BMD_2928	COG2814	Major facilitator Superfamily
BMD_2929	COG1764	response to oxidative stress
BMD_2931	COG2311	Membrane
BMD_2941	COG0559	Belongs to the binding-protein-dependent transport system permease family
BMD_2943	COG0347	Belongs to the P(II) protein family
BMD_2944	COG0004	ammonium transporteR
BMD_2949	COG0596	Alpha beta hydrolase
BMD_2952	COG0456	acetyltransferase
BMD_2952	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BMD_2954	COG1960	acyl-CoA dehydrogenase activity
BMD_2962	COG4604	ABC transporter, ATP-binding protein
BMD_2963	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BMD_2964	COG1492	cobalamin metabolic process
BMD_2966	COG0531	amino acid
BMD_2968	COG1028	Short-chain dehydrogenase reductase Sdr
BMD_2969	COG2404	hydrolase activity, acting on ester bonds
BMD_2970	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BMD_2972	COG1609	Transcriptional regulator
BMD_2974	COG2271	Major facilitator Superfamily
BMD_2975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BMD_2978	COG1233	COG1233 Phytoene dehydrogenase and related
BMD_2979	COG0463	Glycosyl transferase, family 2
BMD_2989	COG0804	urea catabolic process
BMD_2991	COG0831	urea catabolic process
BMD_2992	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BMD_2993	COG1388	LysM domain
BMD_2993	COG0791	NLP P60 protein
BMD_2994	COG3583	domain protein
BMD_2994	COG3584	3D domain protein
BMD_2995	COG0778	Nitroreductase
BMD_2996	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BMD_2997	COG0586	Pfam SNARE associated Golgi protein
BMD_2999	COG0400	carboxylic ester hydrolase activity
BMD_3000	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BMD_3001	COG2244	polysaccharide biosynthetic process
BMD_3002	COG0697	spore germination
BMD_3003	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BMD_3007	COG1132	(ABC) transporter
BMD_3012	COG4195	phage-related replication protein
BMD_3016	COG0783	Belongs to the Dps family
BMD_3017	COG0783	Belongs to the Dps family
BMD_3019	COG5577	PFAM Coat F domain
BMD_3020	COG1253	flavin adenine dinucleotide binding
BMD_3022	COG0516	GMP reductase activity
BMD_3022	COG0517	IMP dehydrogenase activity
BMD_3025	COG0723	plastoquinol--plastocyanin reductase activity
BMD_3025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BMD_3028	COG0287	Prephenate dehydrogenase
BMD_3030	COG1605	Chorismate mutase
BMD_3030	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BMD_3032	COG2059	Chromate
BMD_3033	COG2059	Chromate
BMD_3035	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BMD_3036	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BMD_3037	COG2508	Transcriptional regulator
BMD_3038	COG0011	TIGRFAM Protein of
BMD_3039	COG0791	NLP P60 protein
BMD_3039	COG1388	LysM domain
BMD_3040	COG0753	catalase activity
BMD_3042	COG0733	neurotransmitter:sodium symporter activity
BMD_3050	COG0730	response to heat
BMD_3051	COG1902	pentaerythritol trinitrate reductase activity
BMD_3056	COG0640	Transcriptional regulator
BMD_3058	COG0778	Nitroreductase
BMD_3061	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BMD_3062	COG3103	Sh3 type 3 domain protein
BMD_3062	COG0860	N-Acetylmuramoyl-L-alanine amidase
BMD_3062	COG4991	sh3 domain protein
BMD_3063	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BMD_3064	COG2002	toxin-antitoxin pair type II binding
BMD_3065	COG2318	DinB family
BMD_3066	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BMD_3069	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BMD_3070	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BMD_3073	COG2211	Major facilitator Superfamily
BMD_3074	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BMD_3075	COG1597	lipid kinase activity
BMD_3077	COG0372	Belongs to the citrate synthase family
BMD_3079	COG0583	DNA-binding transcription factor activity
BMD_3080	COG0697	spore germination
BMD_3081	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BMD_3085	COG1366	Belongs to the anti-sigma-factor antagonist family
BMD_3085	COG2202	Pas domain
BMD_3086	COG1366	Belongs to the anti-sigma-factor antagonist family
BMD_3092	COG1366	Belongs to the anti-sigma-factor antagonist family
BMD_3093	COG2261	transglycosylase associated protein
BMD_3096	COG0740	serine-type endopeptidase activity
BMD_3099	COG1027	Aspartate ammonia-lyase
BMD_3100	COG0252	asparaginase activity
BMD_3101	COG1396	sequence-specific DNA binding
BMD_3105	COG0640	Transcriptional regulator
BMD_3109	COG0531	amino acid
BMD_3110	COG1959	2 iron, 2 sulfur cluster binding
BMD_3115	COG0281	malic enzyme
BMD_3116	COG2746	aminoglycoside 3-N-acetyltransferase activity
BMD_3118	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BMD_3119	COG1028	Short-chain dehydrogenase reductase Sdr
BMD_3121	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BMD_3122	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BMD_3125	COG0477	Major facilitator Superfamily
BMD_3126	COG1846	Transcriptional regulator
BMD_3127	COG0789	Transcriptional regulator
BMD_3128	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BMD_3136	COG1819	glycosyl
BMD_3139	COG1902	pentaerythritol trinitrate reductase activity
BMD_3141	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BMD_3144	COG2814	Major facilitator Superfamily
BMD_3146	COG1228	amidohydrolase
BMD_3148	COG1316	TRANSCRIPTIONal
BMD_3149	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BMD_3153	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BMD_3155	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BMD_3156	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BMD_3168	COG0860	N-Acetylmuramoyl-L-alanine amidase
BMD_3169	COG1280	lysine exporter protein (LysE YggA)
BMD_3170	COG0531	amino acid
BMD_3175	COG3764	Sortase (surface protein transpeptidase)
BMD_3176	COG0730	response to heat
BMD_3177	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BMD_3178	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BMD_3180	COG2130	NADP-dependent
BMD_3185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BMD_3189	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BMD_3191	COG0501	Belongs to the peptidase M48B family
BMD_3199	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BMD_3199	COG0131	Imidazoleglycerol-phosphate dehydratase
BMD_3201	COG1309	transcriptional regulator
BMD_3202	COG2076	Multidrug Resistance protein
BMD_3203	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BMD_3204	COG1278	Cold shock
BMD_3205	COG2323	membrane
BMD_3208	COG2910	NAD(P)H-binding
BMD_3215	COG3546	catalase activity
BMD_3216	COG4607	ABC-type enterochelin transport system periplasmic component
BMD_3217	COG4604	ABC transporter, ATP-binding protein
BMD_3218	COG4605	iron ion homeostasis
BMD_3219	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BMD_3220	COG3773	Cell wall hydrolase
BMD_3223	COG2249	NAD(P)H dehydrogenase (quinone) activity
BMD_3224	COG0681	Belongs to the peptidase S26 family
BMD_3229	COG1349	DNA-binding transcription factor activity
BMD_3230	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BMD_3232	COG1193	negative regulation of DNA recombination
BMD_3234	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BMD_3235	COG1396	sequence-specific DNA binding
BMD_3236	COG0861	Integral membrane protein TerC family
BMD_3238	COG1609	Transcriptional regulator
BMD_3239	COG1959	2 iron, 2 sulfur cluster binding
BMD_3245	COG3773	Cell wall hydrolase
BMD_3246	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BMD_3251	COG3546	catalase activity
BMD_3255	COG1280	lysine exporter protein (LysE YggA)
BMD_3256	COG2207	Transcriptional regulator
BMD_3256	COG1917	Cupin 2, conserved barrel domain protein
BMD_3257	COG2203	Gaf domain
BMD_3257	COG4585	Histidine kinase
BMD_3261	COG3209	COG3209 Rhs family protein
BMD_3266	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BMD_3268	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BMD_3272	COG0346	lactoylglutathione lyase activity
BMD_3273	COG1136	(ABC) transporter
BMD_3274	COG0577	efflux transmembrane transporter activity
BMD_3275	COG3850	Histidine kinase
BMD_3275	COG5002	protein histidine kinase activity
BMD_3280	COG5002	protein histidine kinase activity
BMD_3281	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BMD_3282	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BMD_3288	COG4989	oxidoreductase activity
BMD_3291	COG0697	spore germination
BMD_3292	COG2207	Transcriptional regulator
BMD_3292	COG1917	Cupin 2, conserved barrel domain protein
BMD_3307	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BMD_3309	COG0583	DNA-binding transcription factor activity
BMD_3311	COG1301	dicarboxylic acid transport
BMD_3312	COG2824	Alkylphosphonate utilization operon protein PhnA
BMD_3318	COG0405	Gamma-glutamyltransferase
BMD_3319	COG1073	alpha beta
BMD_3322	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BMD_3323	COG4521	taurine ABC transporter
BMD_3325	COG2175	clavaminate synthase activity
BMD_3326	COG2814	Major facilitator Superfamily
BMD_3330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BMD_3332	COG1960	acyl-CoA dehydrogenase activity
BMD_3333	COG1063	alcohol dehydrogenase
BMD_3334	COG0745	RESPONSE REGULATOR receiver
BMD_3335	COG0642	Histidine kinase
BMD_3336	COG1136	(ABC) transporter
BMD_3337	COG0577	efflux transmembrane transporter activity
BMD_3339	COG0412	Dienelactone hydrolase
BMD_3340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BMD_3342	COG0730	response to heat
BMD_3343	COG0425	Belongs to the sulfur carrier protein TusA family
BMD_3344	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BMD_3344	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BMD_3345	COG0425	Belongs to the sulfur carrier protein TusA family
BMD_3345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BMD_3348	COG2210	Belongs to the sulfur carrier protein TusA family
BMD_3349	COG0425	Belongs to the sulfur carrier protein TusA family
BMD_3350	COG1937	Protein conserved in bacteria
BMD_3354	COG0583	DNA-binding transcription factor activity
BMD_3358	COG2188	Transcriptional regulator
BMD_3359	COG2723	6-phospho-beta-galactosidase activity
BMD_3365	COG1280	lysine exporter protein (LysE YggA)
BMD_3366	COG3695	enzyme binding
BMD_3368	COG0583	DNA-binding transcription factor activity
BMD_3369	COG0346	lactoylglutathione lyase activity
BMD_3371	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BMD_3375	COG0778	Nitroreductase
BMD_3376	COG1012	belongs to the aldehyde dehydrogenase family
BMD_3379	COG1704	LemA family
BMD_3380	COG0726	polysaccharide deacetylase
BMD_3383	COG1733	regulation of RNA biosynthetic process
BMD_3384	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BMD_3385	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BMD_3386	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BMD_3389	COG2304	oxidoreductase activity
BMD_3391	COG0346	lactoylglutathione lyase activity
BMD_3392	COG2808	Putative FMN-binding domain
BMD_3398	COG4807	Protein conserved in bacteria
BMD_3400	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BMD_3401	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BMD_3402	COG1278	Cold shock
BMD_3404	COG1278	Cold shock
BMD_3406	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BMD_3407	COG1301	dicarboxylic acid transport
BMD_3410	COG0477	Major facilitator Superfamily
BMD_3416	COG0659	secondary active sulfate transmembrane transporter activity
BMD_3418	COG2211	Major facilitator Superfamily
BMD_3420	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
BMD_3421	COG1691	(AIR) carboxylase
BMD_3422	COG1606	tRNA processing
BMD_3423	COG1028	Short-chain dehydrogenase reductase Sdr
BMD_3425	COG1904	glucuronate isomerase
BMD_3430	COG1131	(ABC) transporter
BMD_3436	COG0561	phosphatase activity
BMD_3438	COG2312	Erythromycin esterase
BMD_3441	COG2329	Antibiotic biosynthesis monooxygenase
BMD_3443	COG0745	RESPONSE REGULATOR receiver
BMD_3446	COG1131	(ABC) transporter
BMD_3451	COG3655	Transcriptional regulator
BMD_3453	COG0583	DNA-binding transcription factor activity
BMD_3454	COG1028	Short-chain dehydrogenase reductase Sdr
BMD_3456	COG1082	Xylose isomerase domain protein TIM barrel
BMD_3457	COG4977	sequence-specific DNA binding
BMD_3457	COG1917	Cupin 2, conserved barrel domain protein
BMD_3459	COG1609	Transcriptional regulator
BMD_3460	COG1082	Xylose isomerase domain protein TIM barrel
BMD_3461	COG0673	inositol 2-dehydrogenase activity
BMD_3465	COG3718	enzyme involved in inositol metabolism
BMD_3466	COG3962	Belongs to the TPP enzyme family
BMD_3467	COG1349	DNA-binding transcription factor activity
BMD_3468	COG0191	fructose-bisphosphate aldolase activity
BMD_3469	COG1082	Xylose isomerase domain protein TIM barrel
BMD_3470	COG2814	Major facilitator Superfamily
BMD_3472	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BMD_3473	COG1064	alcohol dehydrogenase
BMD_3474	COG0789	Transcriptional regulator
BMD_3477	COG0662	Cupin 2, conserved barrel domain protein
BMD_3481	COG1366	Belongs to the anti-sigma-factor antagonist family
BMD_3482	COG1278	Cold shock
BMD_3485	COG1876	peptidase activity
BMD_3490	COG0598	Magnesium transport protein CorA
BMD_3491	COG1366	Belongs to the anti-sigma-factor antagonist family
BMD_3493	COG1028	Short-chain dehydrogenase reductase Sdr
BMD_3497	COG1028	Short-chain dehydrogenase reductase Sdr
BMD_3500	COG4335	DNA alkylation repair
BMD_3501	COG0454	-acetyltransferase
BMD_3503	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BMD_3505	COG2814	Major facilitator Superfamily
BMD_3506	COG3848	Pyruvate phosphate dikinase
BMD_3506	COG0574	Belongs to the PEP-utilizing enzyme family
BMD_3507	COG0574	Belongs to the PEP-utilizing enzyme family
BMD_3507	COG3848	Pyruvate phosphate dikinase
BMD_3508	COG2186	Transcriptional regulator
BMD_3513	COG3619	membrane
BMD_3515	COG1349	DNA-binding transcription factor activity
BMD_3516	COG0561	phosphatase activity
BMD_3518	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BMD_3520	COG1280	lysine exporter protein (LysE YggA)
BMD_3527	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BMD_3530	COG2160	L-arabinose isomerase activity
BMD_3533	COG1609	Transcriptional regulator
BMD_3534	COG1078	dGTPase activity
BMD_3536	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BMD_3537	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BMD_3538	COG1918	ferrous iron import across plasma membrane
BMD_3538	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BMD_3544	COG1846	Transcriptional regulator
BMD_3550	COG1388	LysM domain
BMD_3550	COG0791	NLP P60 protein
BMD_3551	COG2258	MOSC domain
BMD_3552	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BMD_3566	COG3844	kynureninase activity
BMD_3567	COG1113	amino acid transport
BMD_3568	COG3483	tryptophan 2,3-dioxygenase activity
BMD_3569	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BMD_3570	COG1942	4-Oxalocrotonate Tautomerase
BMD_3576	COG0251	oxidation-reduction process
BMD_3579	COG0431	NADPH-dependent FMN reductase
BMD_3580	COG0196	riboflavin kinase activity
BMD_3581	COG2368	4-hydroxyphenylacetate
BMD_3585	COG0789	Transcriptional regulator
BMD_3586	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BMD_3587	COG2211	Major facilitator Superfamily
BMD_3588	COG1063	alcohol dehydrogenase
BMD_3589	COG0457	Tetratricopeptide repeat
BMD_3595	COG5646	InterPro IPR014922
BMD_3596	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BMD_3601	COG0598	Magnesium transport protein CorA
BMD_3602	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BMD_3604	COG3227	Zinc metalloprotease (Elastase)
BMD_3605	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BMD_3608	COG2030	dehydratase
BMD_3609	COG4670	ketone body catabolic process
BMD_3611	COG0583	DNA-binding transcription factor activity
BMD_3612	COG0604	alcohol dehydrogenase
BMD_3613	COG0640	Transcriptional regulator
BMD_3617	COG1028	Short-chain dehydrogenase reductase Sdr
BMD_3619	COG2814	Major facilitator Superfamily
BMD_3620	COG1082	Xylose isomerase domain protein TIM barrel
BMD_3621	COG0673	inositol 2-dehydrogenase activity
BMD_3622	COG0673	inositol 2-dehydrogenase activity
BMD_3626	COG0784	Response regulator, receiver
BMD_3626	COG2205	protein histidine kinase activity
BMD_3629	COG5577	PFAM Coat F domain
BMD_3630	COG1063	alcohol dehydrogenase
BMD_3632	COG5577	PFAM Coat F domain
BMD_3633	COG1366	Belongs to the anti-sigma-factor antagonist family
BMD_3634	COG1366	Belongs to the anti-sigma-factor antagonist family
BMD_3635	COG1366	Belongs to the anti-sigma-factor antagonist family
BMD_3640	COG1942	4-Oxalocrotonate Tautomerase
BMD_3641	COG0583	DNA-binding transcription factor activity
BMD_3649	COG2267	carboxylic ester hydrolase activity
BMD_3651	COG1335	isochorismatase
BMD_3653	COG0346	lactoylglutathione lyase activity
BMD_3654	COG2259	Doxx family
BMD_3656	COG0039	L-malate dehydrogenase activity
BMD_3658	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
BMD_3661	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BMD_3662	COG1454	alcohol dehydrogenase
BMD_3662	COG1012	belongs to the aldehyde dehydrogenase family
BMD_3663	COG4816	utilization protein
BMD_3664	COG4302	ethanolamine ammonia-lyase activity
BMD_3665	COG4303	Ethanolamine ammonia lyase large subunit
BMD_3667	COG4917	ethanolamine utilization protein
BMD_3668	COG4810	utilization protein
BMD_3669	COG3192	ethanolamine utilization protein
BMD_3676	COG1309	transcriptional regulator
BMD_3677	COG2076	Multidrug Resistance protein
BMD_3681	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BMD_3683	COG2851	Citrate transporter
BMD_3685	COG0477	Major facilitator Superfamily
BMD_3687	COG0477	Major facilitator Superfamily
BMD_3688	COG1309	transcriptional regulator
BMD_3693	COG0156	8-amino-7-oxononanoate synthase activity
BMD_3694	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BMD_3696	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BMD_3696	COG1263	PTS System
BMD_3698	COG1378	Sugar-specific transcriptional regulator TrmB
BMD_3699	COG0697	spore germination
BMD_3703	COG3238	Protein conserved in bacteria
BMD_3704	COG0583	DNA-binding transcription factor activity
BMD_3706	COG0697	spore germination
BMD_3707	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BMD_3708	COG1027	Aspartate ammonia-lyase
BMD_3709	COG3773	Cell wall hydrolase
BMD_3710	COG1994	Peptidase M50
BMD_3711	COG2261	transglycosylase associated protein
BMD_3714	COG1028	Short-chain dehydrogenase reductase Sdr
BMD_3715	COG0656	L-ascorbic acid biosynthetic process
BMD_3718	COG2814	Major facilitator Superfamily
BMD_3723	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BMD_3728	COG1266	CAAX protease self-immunity
BMD_3733	COG0252	asparaginase activity
BMD_3737	COG1695	Transcriptional regulator
BMD_3739	COG0583	DNA-binding transcription factor activity
BMD_3741	COG2814	Major facilitator Superfamily
BMD_3743	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BMD_3745	COG0281	malic enzyme
BMD_3746	COG2404	hydrolase activity, acting on ester bonds
BMD_3757	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BMD_3760	COG1609	Transcriptional regulator
BMD_3775	COG3708	Transcriptional regulator
BMD_3775	COG2207	Transcriptional regulator
BMD_3778	COG3339	Conserved Protein
BMD_3781	COG0303	'Molybdopterin
BMD_3783	COG0521	Mo-molybdopterin cofactor biosynthetic process
BMD_3784	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BMD_3786	COG2244	polysaccharide biosynthetic process
BMD_3790	COG2828	Protein conserved in bacteria
BMD_3791	COG0583	DNA-binding transcription factor activity
BMD_3792	COG2851	Citrate transporter
BMD_3797	COG0670	Belongs to the BI1 family
BMD_3801	COG0791	NLP P60 protein
BMD_3802	COG2814	Major facilitator Superfamily
BMD_3803	COG1846	Transcriptional regulator
BMD_3807	COG1278	Cold shock
BMD_3811	COG1113	amino acid transport
BMD_3812	COG1113	amino acid transport
BMD_3813	COG1012	belongs to the aldehyde dehydrogenase family
BMD_3814	COG0506	proline dehydrogenase activity
BMD_3815	COG3878	Protein conserved in bacteria
BMD_3819	COG0860	N-Acetylmuramoyl-L-alanine amidase
BMD_3821	COG3300	MHYT domain
BMD_3821	COG5001	Diguanylate cyclase
BMD_3831	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BMD_3832	COG5609	conserved protein (DUF2294)
BMD_3833	COG3223	Belongs to the PsiE family
BMD_3843	COG0789	Transcriptional regulator
BMD_3844	COG0667	Aldo Keto reductase
BMD_3846	COG0789	Transcriptional regulator
BMD_3852	COG1621	beta-fructofuranosidase activity
BMD_3853	COG4980	gas vesicle protein
BMD_3858	COG1752	Esterase of the alpha-beta hydrolase superfamily
BMD_3859	COG0577	efflux transmembrane transporter activity
BMD_3860	COG1136	(ABC) transporter
BMD_3862	COG0642	Histidine kinase
BMD_3863	COG0745	RESPONSE REGULATOR receiver
BMD_3865	COG1289	transmembrane transporter activity
BMD_3866	COG1937	Protein conserved in bacteria
BMD_3867	COG3209	COG3209 Rhs family protein
BMD_3869	COG3973	AAA domain
BMD_3870	COG1024	Enoyl-CoA hydratase
BMD_3871	COG1733	regulation of RNA biosynthetic process
BMD_3874	COG2124	cytochrome p450
BMD_3875	COG2259	Doxx family
BMD_3876	COG0463	Glycosyl transferase, family 2
BMD_3878	COG1216	Glycosyl transferase, family 2
BMD_3878	COG1442	glycosyl transferase family 8
BMD_3881	COG0791	NLP P60 protein
BMD_3881	COG1388	LysM domain
BMD_3882	COG0840	transmembrane signaling receptor activity
BMD_3883	COG1846	Transcriptional regulator
BMD_3885	COG1595	DNA-templated transcription, initiation
BMD_3886	COG0726	polysaccharide deacetylase
BMD_3887	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BMD_3890	COG0833	amino acid
BMD_3892	COG0405	Gamma-glutamyltransferase
BMD_3894	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BMD_3895	COG0569	domain protein
BMD_3897	COG1522	sequence-specific DNA binding
BMD_3899	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BMD_3900	COG0745	RESPONSE REGULATOR receiver
BMD_3901	COG2770	Histidine kinase
BMD_3901	COG2205	protein histidine kinase activity
BMD_3902	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BMD_3903	COG1607	acyl-coa hydrolase
BMD_3904	COG1802	Transcriptional regulator
BMD_3905	COG0697	spore germination
BMD_3907	COG0006	proline dipeptidase activity
BMD_3909	COG1316	TRANSCRIPTIONal
BMD_3911	COG2249	NAD(P)H dehydrogenase (quinone) activity
BMD_3912	COG5522	Integral membrane protein (intg_mem_TP0381)
BMD_3914	COG1174	glycine betaine transport
BMD_3915	COG0517	IMP dehydrogenase activity
BMD_3915	COG1125	glycine betaine transport
BMD_3918	COG2814	Major facilitator Superfamily
BMD_3920	COG2205	protein histidine kinase activity
BMD_3921	COG0730	response to heat
BMD_3922	COG1301	dicarboxylic acid transport
BMD_3929	COG1316	TRANSCRIPTIONal
BMD_3930	COG1368	sulfuric ester hydrolase activity
BMD_3932	COG0697	spore germination
BMD_3933	COG1902	pentaerythritol trinitrate reductase activity
BMD_3936	COG1113	amino acid transport
BMD_3937	COG5505	Protein of unknown function (DUF819)
BMD_3938	COG1309	transcriptional regulator
BMD_3940	COG0583	DNA-binding transcription factor activity
BMD_3941	COG0730	response to heat
BMD_3942	COG1247	-acetyltransferase
BMD_3943	COG2910	NAD(P)H-binding
BMD_3944	COG1285	pathogenesis
BMD_3945	COG2226	methyltransferase
BMD_3946	COG4195	phage-related replication protein
BMD_3948	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BMD_3951	COG1113	amino acid transport
BMD_3956	COG0463	Glycosyl transferase, family 2
BMD_3962	COG2514	catechol 2,3-dioxygenase activity
BMD_3966	COG1280	lysine exporter protein (LysE YggA)
BMD_3967	COG1115	amino acid carrier protein
BMD_3969	COG0385	Bile acid
BMD_3970	COG0668	transmembrane transport
BMD_3971	COG2340	Cysteine-rich secretory protein family
BMD_3972	COG1253	flavin adenine dinucleotide binding
BMD_3974	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BMD_3975	COG0589	response to stress
BMD_3977	COG0205	6-phosphofructokinase activity
BMD_3978	COG1388	LysM domain
BMD_3978	COG0791	NLP P60 protein
BMD_3982	COG0432	Pfam Uncharacterised protein family UPF0047
BMD_3983	COG0697	spore germination
BMD_3984	COG0814	amino acid
BMD_3989	COG1131	(ABC) transporter
BMD_3992	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BMD_3995	COG0584	glycerophosphoryl diester phosphodiesterase
BMD_4002	COG1263	PTS System
BMD_4002	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BMD_4003	COG3711	transcriptional antiterminator
BMD_4004	COG2190	(PTS) system
BMD_4005	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BMD_4008	COG0772	Belongs to the SEDS family
BMD_4009	COG0659	secondary active sulfate transmembrane transporter activity
BMD_4010	COG0813	purine-nucleoside phosphorylase activity
BMD_4013	COG0671	phosphoesterase, PA-phosphatase related
BMD_4015	COG4326	sporulation control protein
BMD_4016	COG2815	serine threonine protein kinase
BMD_4016	COG0515	serine threonine protein kinase
BMD_4021	COG4479	Belongs to the UPF0346 family
BMD_4022	COG3594	Acyltransferase
BMD_4025	COG1509	lysine 2,3-aminomutase activity
BMD_4026	COG0456	acetyltransferase
BMD_4027	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BMD_4028	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BMD_4029	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BMD_4030	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BMD_4031	COG1301	dicarboxylic acid transport
BMD_4033	COG4191	Histidine kinase
BMD_4038	COG2755	lipolytic protein G-D-S-L family
BMD_4039	COG1999	signal sequence binding
BMD_4041	COG1307	EDD domain protein, DegV family
BMD_4043	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BMD_4044	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BMD_4045	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BMD_4046	COG0788	formyltetrahydrofolate deformylase activity
BMD_4053	COG0076	glutamate decarboxylase activity
BMD_4057	COG0415	Belongs to the DNA photolyase family
BMD_4058	COG3852	Histidine kinase
BMD_4061	COG1012	belongs to the aldehyde dehydrogenase family
BMD_4063	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BMD_4065	COG4846	Membrane protein involved in cytochrome C biogenesis
BMD_4067	COG0785	Cytochrome C biogenesis protein
BMD_4069	COG1132	(ABC) transporter
BMD_4070	COG1132	(ABC) transporter
BMD_4074	COG4224	UPF0291 protein
BMD_4075	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BMD_4081	COG0463	Glycosyl transferase, family 2
BMD_4082	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BMD_4083	COG0531	amino acid
BMD_4086	COG0174	glutamine synthetase
BMD_4087	COG0789	Transcriptional regulator
BMD_4088	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BMD_4089	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BMD_4090	COG2860	membrane
BMD_4091	COG0464	growth
BMD_4093	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BMD_4095	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BMD_4096	COG0531	amino acid
BMD_4098	COG4550	Control of competence regulator ComK, YlbF/YmcA
BMD_4099	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BMD_4100	COG1013	pyruvate-flavodoxin oxidoreductase activity
BMD_4101	COG0674	pyruvate-flavodoxin oxidoreductase activity
BMD_4101	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BMD_4103	COG2359	stage V sporulation protein S
BMD_4104	COG1692	metallophosphoesterase
BMD_4106	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BMD_4107	COG1546	Belongs to the CinA family
BMD_4107	COG1058	Belongs to the CinA family
BMD_4108	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BMD_4109	COG1426	Protein conserved in bacteria
BMD_4112	COG0300	oxidoreductase activity
BMD_4113	COG0612	Peptidase, M16
BMD_4114	COG0612	Peptidase, M16
BMD_4119	COG2188	Transcriptional regulator
BMD_4120	COG1674	ftsk spoiiie
BMD_4120	COG4980	gas vesicle protein
BMD_4122	COG0740	serine-type endopeptidase activity
BMD_4123	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BMD_4125	COG0527	aspartate kinase activity
BMD_4126	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BMD_4127	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BMD_4128	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BMD_4129	COG1873	PFAM PRC-barrel domain
BMD_4130	COG0612	Peptidase, M16
BMD_4131	COG0726	polysaccharide deacetylase
BMD_4132	COG1185	polyribonucleotide nucleotidyltransferase activity
BMD_4133	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BMD_4134	COG0196	riboflavin kinase activity
BMD_4137	COG1550	Protein conserved in bacteria
BMD_4139	COG1358	cellular component organization or biogenesis
BMD_4140	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BMD_4141	COG0195	Participates in both transcription termination and antitermination
BMD_4142	COG0779	Required for maturation of 30S ribosomal subunits
BMD_4143	COG2176	DNA-directed DNA polymerase activity
BMD_4144	COG0442	prolyl-tRNA aminoacylation
BMD_4145	COG0750	zinc metalloprotease
BMD_4147	COG4589	Belongs to the CDS family
BMD_4149	COG0233	cytoplasmic translational termination
BMD_4150	COG0528	UMP kinase activity
BMD_4151	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BMD_4154	COG1191	sigma factor activity
BMD_4155	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BMD_4156	COG0835	chemotaxis
BMD_4157	COG0643	Histidine kinase
BMD_4157	COG2198	Histidine kinase
BMD_4158	COG2201	protein-glutamate methylesterase activity
BMD_4159	COG0455	bacterial-type flagellum organization
BMD_4160	COG1419	protein localization to endoplasmic reticulum
BMD_4161	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BMD_4162	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BMD_4163	COG1684	flagellar biosynthetic protein fliR
BMD_4164	COG1987	bacterial-type flagellum assembly
BMD_4165	COG1338	Plays a role in the flagellum-specific transport system
BMD_4166	COG3190	flagellar
BMD_4167	COG2201	protein-glutamate methylesterase activity
BMD_4168	COG1776	CheC inhibitor of MCP methylation
BMD_4168	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BMD_4169	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BMD_4171	COG1582	Flagellar protein (FlbD)
BMD_4172	COG4786	Flagellar basal body rod
BMD_4173	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BMD_4176	COG2882	bacterial-type flagellum organization
BMD_4177	COG1157	protein secretion by the type III secretion system
BMD_4178	COG1317	bacterial-type flagellum organization
BMD_4179	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BMD_4180	COG1766	The M ring may be actively involved in energy transduction
BMD_4181	COG1677	Flagellar hook-basal body complex protein FliE
BMD_4182	COG1558	bacterial-type flagellum-dependent cell motility
BMD_4183	COG1815	bacterial-type flagellum-dependent cell motility
BMD_4184	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BMD_4185	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BMD_4187	COG4974	Belongs to the 'phage' integrase family
BMD_4189	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BMD_4190	COG0758	DNA mediated transformation
BMD_4191	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BMD_4192	COG0045	succinate-CoA ligase (ADP-forming) activity
BMD_4196	COG0335	large ribosomal subunit rRNA binding
BMD_4198	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BMD_4200	COG1837	Belongs to the UPF0109 family
BMD_4201	COG0228	four-way junction DNA binding
BMD_4202	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BMD_4204	COG0552	protein localization to endoplasmic reticulum
BMD_4205	COG1196	nuclear chromosome segregation
BMD_4207	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BMD_4208	COG1028	Short-chain dehydrogenase reductase Sdr
BMD_4209	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BMD_4210	COG0416	fatty acid biosynthetic process
BMD_4211	COG1349	DNA-binding transcription factor activity
BMD_4212	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BMD_4213	COG1760	l-serine dehydratase
BMD_4214	COG1760	l-serine dehydratase
BMD_4216	COG1461	Dihydroxyacetone kinase
BMD_4217	COG1302	Protein conserved in bacteria
BMD_4218	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BMD_4219	COG1564	THIamine pyrophosphokinase
BMD_4220	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BMD_4221	COG1162	GTPase activity
BMD_4222	COG2815	serine threonine protein kinase
BMD_4222	COG0515	serine threonine protein kinase
BMD_4223	COG0631	protein serine/threonine phosphatase activity
BMD_4225	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BMD_4225	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BMD_4226	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BMD_4228	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BMD_4229	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BMD_4230	COG1758	RNA polymerase activity
BMD_4231	COG0194	GDP metabolic process
BMD_4232	COG2052	Domain of unknown function (DUF370)
BMD_4233	COG1561	YicC-like family, N-terminal region
BMD_4234	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BMD_4236	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BMD_4239	COG0543	2 iron, 2 sulfur cluster binding
BMD_4242	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BMD_4245	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BMD_4246	COG0564	pseudouridine synthase activity
BMD_4247	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BMD_4250	COG3599	regulation of cell shape
BMD_4251	COG2302	S4 RNA-binding domain
BMD_4252	COG0762	integral membrane protein
BMD_4253	COG1799	cell septum assembly
BMD_4254	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BMD_4256	COG1873	PFAM PRC-barrel domain
BMD_4257	COG1191	sigma factor activity
BMD_4258	COG1191	sigma factor activity
BMD_4260	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BMD_4261	COG0849	cell division
BMD_4262	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BMD_4263	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BMD_4264	COG0772	Belongs to the SEDS family
BMD_4266	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BMD_4267	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BMD_4268	COG0768	penicillin binding
BMD_4270	COG4839	cell division protein FtsL
BMD_4272	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BMD_4274	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BMD_4275	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BMD_4276	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BMD_4277	COG0439	Biotin carboxylase
BMD_4278	COG0454	-acetyltransferase
BMD_4280	COG1024	Enoyl-CoA hydratase
BMD_4281	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BMD_4282	COG1399	metal-binding, possibly nucleic acid-binding protein
BMD_4283	COG1323	Belongs to the UPF0348 family
BMD_4284	COG3480	Lon protease (S16) C-terminal proteolytic domain
BMD_4285	COG1752	Esterase of the alpha-beta hydrolase superfamily
BMD_4286	COG3314	Sporulation integral membrane protein YlbJ
BMD_4287	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BMD_4288	COG0742	ribosomal rna small subunit methyltransferase
BMD_4290	COG4471	UPF0298 protein
BMD_4291	COG3679	Belongs to the UPF0342 family
BMD_4295	COG4347	Protein of unknown function (DUF1405)
BMD_4297	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BMD_4300	COG5582	Belongs to the UPF0302 family
BMD_4301	COG0457	Tetratricopeptide repeat
BMD_4302	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BMD_4303	COG0287	Prephenate dehydrogenase
BMD_4304	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BMD_4305	COG0159	tryptophan synthase activity
BMD_4307	COG0135	phosphoribosylanthranilate isomerase activity
BMD_4308	COG0134	indole-3-glycerol-phosphate synthase activity
BMD_4309	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BMD_4311	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BMD_4312	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BMD_4313	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BMD_4314	COG0105	UTP biosynthetic process
BMD_4315	COG0142	geranyltranstransferase activity
BMD_4316	COG2226	methyltransferase
BMD_4317	COG0142	geranyltranstransferase activity
BMD_4319	COG0302	gtp cyclohydrolase
BMD_4320	COG0776	regulation of translation
BMD_4321	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BMD_4329	COG1304	FMN binding
BMD_4330	COG0539	negative regulation of cytoplasmic translation
BMD_4332	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BMD_4335	COG2959	enzyme of heme biosynthesis
BMD_4336	COG3409	Peptidoglycan-binding domain 1 protein
BMD_4336	COG3773	Cell wall hydrolase
BMD_4337	COG2339	peptidase activity
BMD_4338	COG0252	asparaginase activity
BMD_4339	COG0492	ferredoxin-NADP+ reductase activity
BMD_4340	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BMD_4341	COG4862	establishment of competence for transformation
BMD_4342	COG0789	Transcriptional regulator
BMD_4343	COG1408	metallophosphoesterase
BMD_4346	COG1266	CAAX protease self-immunity
BMD_4347	COG0514	ATP-dependent DNA helicase (RecQ)
BMD_4350	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BMD_4351	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BMD_4352	COG0739	heme binding
BMD_4353	COG5002	protein histidine kinase activity
BMD_4354	COG0745	RESPONSE REGULATOR receiver
BMD_4355	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BMD_4356	COG1333	cytochrome c biogenesis protein
BMD_4357	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BMD_4358	COG1187	pseudouridine synthase activity
BMD_4359	COG0700	Nucleoside recognition
BMD_4360	COG2715	membrane protein required for spore maturation
BMD_4361	COG1686	Belongs to the peptidase S11 family
BMD_4362	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BMD_4363	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BMD_4365	COG1547	Domain of unknown function (DUF309)
BMD_4367	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BMD_4368	COG4086	secreted protein
BMD_4370	COG0697	spore germination
BMD_4373	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BMD_4380	COG1686	Belongs to the peptidase S11 family
BMD_4383	COG4974	Belongs to the 'phage' integrase family
BMD_4385	COG0735	belongs to the Fur family
BMD_4386	COG1300	Membrane
BMD_4387	COG0494	nUDIX hydrolase
BMD_4389	COG0667	Aldo Keto reductase
BMD_4391	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BMD_4392	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BMD_4394	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BMD_4395	COG1073	alpha beta
BMD_4398	COG0300	oxidoreductase activity
BMD_4399	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BMD_4400	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BMD_4401	COG1902	pentaerythritol trinitrate reductase activity
BMD_4403	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BMD_4404	COG1012	belongs to the aldehyde dehydrogenase family
BMD_4405	COG2508	Transcriptional regulator
BMD_4409	COG0167	dihydroorotate dehydrogenase activity
BMD_4409	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BMD_4410	COG0493	'glutamate synthase
BMD_4411	COG2195	Cleaves the N-terminal amino acid of tripeptides
BMD_4412	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BMD_4414	COG1376	ErfK ybiS ycfS ynhG family protein
BMD_4415	COG4129	membrane
BMD_4416	COG1126	abc transporter atp-binding protein
BMD_4417	COG0765	amino acid transport
BMD_4418	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BMD_4420	COG1703	isobutyryl-CoA mutase activity
BMD_4421	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BMD_4421	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BMD_4423	COG0508	dehydrogenase complex catalyzes the overall conversion of
BMD_4424	COG0022	dehydrogenase e1 component
BMD_4425	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BMD_4426	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BMD_4429	COG0280	phosphate acetyltransferase
BMD_4430	COG3290	protein histidine kinase activity
BMD_4430	COG3829	transcription factor binding
BMD_4432	COG0584	glycerophosphoryl diester phosphodiesterase
BMD_4433	COG3093	addiction module antidote protein HigA
BMD_4434	COG3104	oligopeptide transport
BMD_4436	COG0745	RESPONSE REGULATOR receiver
BMD_4437	COG0750	zinc metalloprotease
BMD_4438	COG0497	DNA recombination
BMD_4440	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BMD_4443	COG1722	exodeoxyribonuclease VII activity
BMD_4445	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BMD_4446	COG1302	Protein conserved in bacteria
BMD_4447	COG0439	Biotin carboxylase
BMD_4448	COG0511	ligase activity, forming carbon-carbon bonds
BMD_4456	COG3854	ATPases associated with a variety of cellular activities
BMD_4458	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BMD_4459	COG0006	proline dipeptidase activity
BMD_4460	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BMD_4462	COG3872	metal-dependent enzyme
BMD_4464	COG1752	Esterase of the alpha-beta hydrolase superfamily
BMD_4465	COG1321	iron dependent repressor
BMD_4467	COG0095	Lipoate-protein ligase
BMD_4468	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BMD_4470	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BMD_4471	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BMD_4472	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BMD_4478	COG4970	Tfp pilus assembly protein FimT
BMD_4479	COG4537	Required for transformation and DNA binding
BMD_4480	COG1459	type II secretion system
BMD_4481	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BMD_4482	COG1393	Belongs to the ArsC family
BMD_4484	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BMD_4486	COG2866	Carboxypeptidase
BMD_4487	COG1940	carbohydrate kinase activity
BMD_4488	COG4483	Protein conserved in bacteria
BMD_4489	COG0457	Tetratricopeptide repeat
BMD_4489	COG0705	Rhomboid family
BMD_4492	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BMD_4494	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BMD_4497	COG0704	Plays a role in the regulation of phosphate uptake
BMD_4501	COG0477	Major facilitator Superfamily
BMD_4508	COG2839	Protein conserved in bacteria
BMD_4511	COG2814	Major facilitator Superfamily
BMD_4512	COG1388	LysM domain
BMD_4513	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BMD_4514	COG4709	membrane
BMD_4515	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BMD_4516	COG0735	belongs to the Fur family
BMD_4517	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BMD_4518	COG1121	(ABC) transporter
BMD_4520	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BMD_4521	COG0513	Belongs to the DEAD box helicase family
BMD_4523	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BMD_4524	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BMD_4525	COG2384	SAM-dependent methyltransferase
BMD_4526	COG2010	Cytochrome c
BMD_4527	COG1960	acyl-CoA dehydrogenase activity
BMD_4528	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BMD_4529	COG0358	DNA primase activity
BMD_4530	COG1671	Belongs to the UPF0178 family
BMD_4531	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BMD_4532	COG0517	IMP dehydrogenase activity
BMD_4534	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BMD_4535	COG0295	cytidine deaminase activity
BMD_4536	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BMD_4538	COG1480	7TM receptor with intracellular HD hydrolase
BMD_4539	COG1702	phosphate starvation-inducible protein PhoH
BMD_4544	COG1030	water channel activity
BMD_4545	COG1610	YqeY-like protein
BMD_4546	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BMD_4547	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BMD_4548	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BMD_4549	COG2264	protein methyltransferase activity
BMD_4552	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BMD_4553	COG1420	regulation of RNA biosynthetic process
BMD_4554	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BMD_4555	COG0481	GTPase activity
BMD_4557	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BMD_4558	COG0268	Binds directly to 16S ribosomal RNA
BMD_4559	COG1466	dna polymerase III delta subunit
BMD_4561	COG0658	competence protein
BMD_4561	COG2333	competence protein COMEC
BMD_4562	COG2131	deaminase
BMD_4563	COG1596	polysaccharide export
BMD_4563	COG1555	photosystem II stabilization
BMD_4564	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BMD_4565	COG2226	methyltransferase
BMD_4566	COG0799	negative regulation of ribosome biogenesis
BMD_4567	COG1713	HD superfamily hydrolase involved in NAD metabolism
BMD_4568	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BMD_4569	COG1534	Rna-binding protein
BMD_4570	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BMD_4571	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BMD_4572	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BMD_4574	COG0688	phosphatidylethanolamine metabolic process
BMD_4575	COG1183	phosphatidylcholine synthase activity
BMD_4577	COG1191	sigma factor activity
BMD_4580	COG0626	cystathionine gamma-synthase activity
BMD_4581	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BMD_4582	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BMD_4583	COG2226	methyltransferase
BMD_4586	COG0768	penicillin binding
BMD_4587	COG1335	isochorismatase
BMD_4588	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BMD_4589	COG0572	uridine kinase
BMD_4593	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BMD_4594	COG3906	Belongs to the UPF0473 family
BMD_4596	COG4472	Bacterial protein of unknown function (DUF965)
BMD_4599	COG0628	permease
BMD_4602	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BMD_4604	COG0482	sulfurtransferase activity
BMD_4605	COG1104	cysteine desulfurase activity
BMD_4606	COG1959	2 iron, 2 sulfur cluster binding
BMD_4607	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BMD_4608	COG0581	inorganic phosphate transmembrane transporter activity
BMD_4609	COG0573	inorganic phosphate transmembrane transporter activity
BMD_4610	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BMD_4611	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BMD_4612	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BMD_4613	COG0124	histidyl-tRNA synthetase
BMD_4615	COG0860	N-Acetylmuramoyl-L-alanine amidase
BMD_4616	COG1490	D-aminoacyl-tRNA deacylase activity
BMD_4617	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BMD_4618	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BMD_4619	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BMD_4619	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BMD_4620	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BMD_4620	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BMD_4622	COG2244	polysaccharide biosynthetic process
BMD_4623	COG2323	membrane
BMD_4625	COG1862	Preprotein translocase
BMD_4627	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BMD_4629	COG2255	four-way junction helicase activity
BMD_4635	COG1388	LysM domain
BMD_4636	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BMD_4637	COG0157	Belongs to the NadC ModD family
BMD_4638	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BMD_4639	COG1104	cysteine desulfurase activity
BMD_4640	COG1827	regulation of RNA biosynthetic process
BMD_4641	COG0077	Prephenate dehydratase
BMD_4642	COG4492	Belongs to the UPF0735 family
BMD_4643	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BMD_4644	COG3290	protein histidine kinase activity
BMD_4646	COG2868	ribosomal protein
BMD_4648	COG1530	ribonuclease E activity
BMD_4649	COG1994	Peptidase M50
BMD_4650	COG0739	heme binding
BMD_4651	COG2894	cell division
BMD_4652	COG0850	regulation of cytokinetic process
BMD_4653	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BMD_4654	COG1792	Involved in formation and maintenance of cell shape
BMD_4655	COG1077	Cell shape determining protein MreB Mrl
BMD_4656	COG2003	Belongs to the UPF0758 family
BMD_4659	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BMD_4661	COG2322	membrane
BMD_4662	COG0285	dihydrofolate synthase activity
BMD_4663	COG0525	valine-tRNA ligase activity
BMD_4665	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BMD_4666	COG1388	LysM domain
BMD_4667	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BMD_4668	COG0113	porphobilinogen synthase activity
BMD_4669	COG1587	Uroporphyrinogen-III synthase
BMD_4670	COG0181	hydroxymethylbilane synthase activity
BMD_4671	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BMD_4674	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BMD_4675	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BMD_4676	COG0470	DNA polymerase III
BMD_4676	COG1067	ATP-dependent peptidase activity
BMD_4677	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BMD_4678	COG0544	peptidyl-prolyl cis-trans isomerase activity
BMD_4679	COG1477	protein flavinylation
BMD_4679	COG0457	Tetratricopeptide repeat
BMD_4680	COG0066	3-isopropylmalate dehydratase activity
BMD_4681	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BMD_4683	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BMD_4684	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BMD_4685	COG0440	acetolactate synthase activity
BMD_4686	COG0028	Belongs to the TPP enzyme family
BMD_4688	COG0622	Phosphoesterase
BMD_4691	COG5401	PFAM Sporulation and spore germination
BMD_4692	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BMD_4693	COG1846	Transcriptional regulator
BMD_4695	COG0306	phosphate transporter
BMD_4696	COG1392	Phosphate transport regulator
BMD_4697	COG0768	penicillin binding
BMD_4699	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BMD_4700	COG0431	NADPH-dependent FMN reductase
BMD_4701	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BMD_4702	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BMD_4703	COG1116	anion transmembrane transporter activity
BMD_4704	COG0475	glutathione-regulated potassium exporter activity
BMD_4705	COG0490	domain, Protein
BMD_4707	COG2197	response regulator
BMD_4708	COG0824	Thioesterase
BMD_4709	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BMD_4710	COG1053	succinate dehydrogenase
BMD_4711	COG2009	succinate dehydrogenase
BMD_4712	COG1719	4-vinyl reductase, 4VR
BMD_4713	COG0527	aspartate kinase activity
BMD_4715	COG3118	belongs to the thioredoxin family
BMD_4716	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BMD_4717	COG2086	electron transfer activity
BMD_4718	COG1024	Enoyl-CoA hydratase
BMD_4719	COG1309	transcriptional regulator
BMD_4720	COG0318	PFAM AMP-dependent synthetase and ligase
BMD_4721	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BMD_4722	COG3766	membrane
BMD_4723	COG1193	negative regulation of DNA recombination
BMD_4724	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BMD_4724	COG1796	DNA polymerase
BMD_4725	COG1286	toxin biosynthetic process
BMD_4726	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BMD_4727	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BMD_4728	COG0072	phenylalanine-tRNA ligase activity
BMD_4728	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BMD_4730	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BMD_4732	COG1363	Peptidase, m42
BMD_4736	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BMD_4737	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BMD_4738	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BMD_4739	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BMD_4741	COG1484	DNA-dependent DNA replication
BMD_4742	COG3611	Membrane attachment protein
BMD_4743	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BMD_4745	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BMD_4746	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BMD_4747	COG0237	dephospho-CoA kinase activity
BMD_4748	COG1971	Probably functions as a manganese efflux pump
BMD_4749	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BMD_4750	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BMD_4750	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BMD_4751	COG5002	protein histidine kinase activity
BMD_4752	COG0745	RESPONSE REGULATOR receiver
BMD_4754	COG0039	L-malate dehydrogenase activity
BMD_4755	COG0538	isocitrate dehydrogenase activity
BMD_4756	COG0372	Belongs to the citrate synthase family
BMD_4757	COG2707	UPF0756 membrane protein
BMD_4758	COG0628	permease
BMD_4759	COG3030	protein affecting phage T7 exclusion by the F plasmid
BMD_4761	COG0825	malonyl-CoA metabolic process
BMD_4762	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BMD_4763	COG2186	Transcriptional regulator
BMD_4764	COG0281	malic enzyme
BMD_4765	COG0587	DNA-directed DNA polymerase activity
BMD_4768	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BMD_4770	COG4109	DRTGG domain
BMD_4772	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BMD_4775	COG0165	Argininosuccinate lyase
BMD_4776	COG0137	argininosuccinate synthase activity
BMD_4779	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BMD_4780	COG0827	DNA restriction-modification system
BMD_4781	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BMD_4782	COG3874	Sporulation protein YtfJ
BMD_4784	COG1714	RDD family
BMD_4785	COG0616	signal peptide processing
BMD_4786	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BMD_4787	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BMD_4789	COG0301	tRNA thio-modification
BMD_4790	COG1104	cysteine desulfurase activity
BMD_4791	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BMD_4792	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BMD_4793	COG1309	transcriptional regulator
BMD_4794	COG1956	GAF domain-containing protein
BMD_4797	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BMD_4798	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BMD_4799	COG0454	-acetyltransferase
BMD_4800	COG0517	IMP dehydrogenase activity
BMD_4801	COG0123	including yeast histone deacetylase and acetoin utilization protein
BMD_4805	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BMD_4805	COG1605	Chorismate mutase
BMD_4806	COG3118	belongs to the thioredoxin family
BMD_4807	COG4980	gas vesicle protein
BMD_4810	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BMD_4812	COG1674	ftsk spoiiie
BMD_4813	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BMD_4814	COG4848	Belongs to the UPF0354 family
BMD_4815	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BMD_4816	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BMD_4817	COG1363	Peptidase, m42
BMD_4818	COG5584	Small secreted protein
BMD_4819	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BMD_4820	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BMD_4822	COG0510	thiamine kinase activity
BMD_4823	COG1523	belongs to the glycosyl hydrolase 13 family
BMD_4825	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BMD_4826	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BMD_4827	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BMD_4828	COG1349	DNA-binding transcription factor activity
BMD_4829	COG1187	pseudouridine synthase activity
BMD_4830	COG2244	polysaccharide biosynthetic process
BMD_4831	COG2081	HI0933 family
BMD_4833	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BMD_4834	COG0495	leucyl-tRNA aminoacylation
BMD_4836	COG2610	gluconate transmembrane transporter activity
BMD_4837	COG2814	Major facilitator Superfamily
BMD_4840	COG1242	4 iron, 4 sulfur cluster binding
BMD_4841	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BMD_4843	COG2267	carboxylic ester hydrolase activity
BMD_4844	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BMD_4845	COG0671	phosphoesterase, PA-phosphatase related
BMD_4846	COG0438	transferase activity, transferring glycosyl groups
BMD_4847	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BMD_4848	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BMD_4850	COG1506	peptidase
BMD_4851	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BMD_4852	COG1116	anion transmembrane transporter activity
BMD_4853	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BMD_4854	COG0494	nUDIX hydrolase
BMD_4856	COG4824	toxin secretion phage lysis holin
BMD_4857	COG0783	Belongs to the Dps family
BMD_4859	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BMD_4860	COG0288	reversible hydration of carbon dioxide
BMD_4861	COG0523	cobalamin synthesis protein
BMD_4863	COG0254	rRNA binding
BMD_4864	COG1271	oxidase subunit
BMD_4865	COG1294	oxidase, subunit
BMD_4866	COG0716	FMN binding
BMD_4871	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BMD_4872	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BMD_4873	COG4948	Mandelate Racemase Muconate Lactonizing
BMD_4874	COG0318	PFAM AMP-dependent synthetase and ligase
BMD_4875	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BMD_4876	COG0596	Alpha beta hydrolase
BMD_4877	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BMD_4878	COG1169	isochorismate synthase
BMD_4879	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BMD_4881	COG0058	SHG alpha-glucan phosphorylase activity
BMD_4882	COG0297	glycogen (starch) synthase activity
BMD_4883	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BMD_4910	COG0318	PFAM AMP-dependent synthetase and ligase
BMD_4911	COG1285	pathogenesis
BMD_4915	COG0529	Catalyzes the synthesis of activated sulfate
BMD_4917	COG0306	phosphate transporter
BMD_4919	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BMD_4920	COG0346	lactoylglutathione lyase activity
BMD_4921	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BMD_4923	COG0166	Belongs to the GPI family
BMD_4924	COG2111	Na H antiporter
BMD_4924	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BMD_4925	COG2111	Na H antiporter
BMD_4926	COG1006	Multisubunit Na H antiporter MnhC subunit
BMD_4927	COG0651	ATP synthesis coupled electron transport
BMD_4928	COG1863	multisubunit Na H antiporter MnhE subunit
BMD_4929	COG2212	antiporter activity
BMD_4930	COG1320	monovalent cation:proton antiporter activity
BMD_4931	COG1979	alcohol dehydrogenase
BMD_4932	COG2155	Conserved Protein
BMD_4933	COG1098	S1 RNA binding domain
BMD_4934	COG0436	Aminotransferase
BMD_4935	COG1522	sequence-specific DNA binding
BMD_4936	COG2267	carboxylic ester hydrolase activity
BMD_4937	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BMD_4938	COG2032	superoxide dismutase activity
BMD_4941	COG5018	Exonuclease
BMD_4942	COG2050	protein possibly involved in aromatic compounds catabolism
BMD_4944	COG1418	mRNA catabolic process
BMD_4946	COG2056	Na+-H+ antiporter family
BMD_4947	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BMD_4948	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BMD_4949	COG3584	3D domain protein
BMD_4951	COG1252	NADH dehydrogenase
BMD_4952	COG0492	ferredoxin-NADP+ reductase activity
BMD_4954	COG0316	Belongs to the HesB IscA family
BMD_4955	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BMD_4956	COG4844	belongs to the
BMD_4957	COG1252	NADH dehydrogenase
BMD_4958	COG4837	Protein of unknown function (DUF1462)
BMD_4959	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BMD_4960	COG0083	homoserine kinase activity
BMD_4961	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BMD_4962	COG0460	homoserine dehydrogenase
BMD_4963	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BMD_4964	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BMD_4965	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BMD_4966	COG0647	UMP catabolic process
BMD_4967	COG2445	Protein of unknown function DUF86
BMD_4969	COG4470	Protein conserved in bacteria
BMD_4971	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BMD_4972	COG0739	heme binding
BMD_4974	COG3377	Domain of unknown function (DUF1805)
BMD_4975	COG1801	Protein of unknown function DUF72
BMD_4976	COG0719	Fe-S assembly protein
BMD_4977	COG0822	iron-sulfur transferase activity
BMD_4978	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BMD_4979	COG0719	Fe-S assembly protein
BMD_4980	COG0396	ATPase activity
BMD_4981	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BMD_4982	COG1464	Belongs to the NlpA lipoprotein family
BMD_4983	COG2011	ABC-type metal ion transport system permease component
BMD_4984	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BMD_4985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BMD_4986	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BMD_4988	COG0509	glycine decarboxylation via glycine cleavage system
BMD_4989	COG1393	Belongs to the ArsC family
BMD_4990	COG1960	acyl-CoA dehydrogenase activity
BMD_4991	COG0183	Belongs to the thiolase family
BMD_4992	COG1024	Enoyl-CoA hydratase
BMD_4992	COG1250	3-hydroxyacyl-CoA dehydrogenase
BMD_4997	COG1120	ATPase activity
BMD_4998	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BMD_4999	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BMD_5000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BMD_5002	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BMD_5003	COG1309	transcriptional regulator
BMD_5005	COG1028	Short-chain dehydrogenase reductase Sdr
BMD_5006	COG0477	Major facilitator Superfamily
BMD_5007	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BMD_5008	COG0583	DNA-binding transcription factor activity
BMD_5011	COG3850	Histidine kinase
BMD_5011	COG5002	protein histidine kinase activity
BMD_5012	COG0745	RESPONSE REGULATOR receiver
BMD_5013	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BMD_5014	COG0671	phosphoesterase, PA-phosphatase related
BMD_5015	COG1846	Transcriptional regulator
BMD_5016	COG0778	Nitroreductase
BMD_5017	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BMD_5018	COG0314	molybdopterin synthase activity
BMD_5019	COG1763	Mo-molybdopterin cofactor biosynthetic process
BMD_5020	COG0303	'Molybdopterin
BMD_5021	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BMD_5022	COG0746	molybdenum cofactor guanylyltransferase activity
BMD_5024	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BMD_5025	COG5609	conserved protein (DUF2294)
BMD_5026	COG3383	formate dehydrogenase (NAD+) activity
BMD_5027	COG2427	Protein of unknown function (DUF1641)
BMD_5028	COG0725	ABC transporter, periplasmic molybdate-binding protein
BMD_5029	COG4149	molybdate abc transporter
BMD_5030	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BMD_5031	COG0557	exoribonuclease II activity
BMD_5032	COG1647	Serine aminopeptidase, S33
BMD_5033	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BMD_5041	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BMD_5045	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BMD_5047	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BMD_5048	COG1660	Displays ATPase and GTPase activities
BMD_5049	COG1051	belongs to the nudix hydrolase family
BMD_5050	COG0492	ferredoxin-NADP+ reductase activity
BMD_5051	COG0457	Tetratricopeptide repeat
BMD_5052	COG0140	phosphoribosyl-ATP diphosphatase activity
BMD_5052	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BMD_5053	COG0107	imidazoleglycerol-phosphate synthase activity
BMD_5054	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BMD_5055	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BMD_5056	COG0131	Imidazoleglycerol-phosphate dehydratase
BMD_5057	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BMD_5058	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BMD_5059	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BMD_5060	COG0110	maltose O-acetyltransferase activity
BMD_5061	COG0546	phosphoglycolate phosphatase activity
BMD_5062	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BMD_5063	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BMD_5064	COG1950	PFAM Membrane protein of
BMD_5065	COG1983	PspC domain protein
BMD_5066	COG3595	metallopeptidase activity
BMD_5068	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BMD_5069	COG0556	nucleotide-excision repair
BMD_5070	COG2204	response regulator
BMD_5071	COG0506	proline dehydrogenase activity
BMD_5072	COG4897	Protein conserved in bacteria
BMD_5073	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BMD_5074	COG3409	Peptidoglycan-binding domain 1 protein
BMD_5074	COG0793	Belongs to the peptidase S41A family
BMD_5075	COG3883	PFAM NLP P60 protein
BMD_5075	COG0791	NLP P60 protein
BMD_5076	COG2177	Part of the ABC transporter FtsEX involved in
BMD_5077	COG2884	Cell division ATP-binding protein ftsE
BMD_5078	COG0655	NAD(P)H dehydrogenase (quinone) activity
BMD_5080	COG0805	protein transport
BMD_5081	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BMD_5082	COG3540	Alkaline phosphatase
BMD_5083	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BMD_5084	COG0653	protein targeting
BMD_5085	COG0456	acetyltransferase
BMD_5086	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BMD_5088	COG1516	flagellar protein fliS
BMD_5089	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BMD_5091	COG1113	amino acid transport
BMD_5094	COG1454	alcohol dehydrogenase
BMD_5095	COG1510	regulation of RNA biosynthetic process
BMD_5096	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BMD_5097	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BMD_5098	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BMD_5099	COG4786	Flagellar basal body rod
BMD_5099	COG1256	bacterial-type flagellum assembly
BMD_5103	COG1040	competence protein
BMD_5104	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BMD_5105	COG1307	EDD domain protein, DegV family
BMD_5106	COG1728	Protein conserved in bacteria
BMD_5108	COG2197	response regulator
BMD_5109	COG4585	Histidine kinase
BMD_5110	COG1739	Uncharacterized protein family UPF0029
BMD_5111	COG1316	TRANSCRIPTIONal
BMD_5112	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BMD_5113	COG1585	Membrane protein implicated in regulation of membrane protease activity
BMD_5114	COG2268	Band 7 protein
BMD_5115	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BMD_5117	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BMD_5119	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BMD_5120	COG1388	LysM domain
BMD_5120	COG0791	NLP P60 protein
BMD_5121	COG0629	single-stranded DNA binding
BMD_5124	COG4786	Flagellar basal body rod
BMD_5125	COG4786	Flagellar basal body rod
BMD_5126	COG1077	Cell shape determining protein MreB Mrl
BMD_5127	COG1609	Transcriptional regulator
BMD_5128	COG0739	heme binding
BMD_5129	COG2385	sporulation resulting in formation of a cellular spore
BMD_5132	COG4836	Membrane
BMD_5133	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BMD_5134	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BMD_5135	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BMD_5136	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BMD_5137	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BMD_5138	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BMD_5139	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BMD_5140	COG0356	it plays a direct role in the translocation of protons across the membrane
BMD_5143	COG1404	Belongs to the peptidase S8 family
BMD_5144	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BMD_5145	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BMD_5148	COG0698	ribose 5-phosphate isomerase
BMD_5150	COG1971	Probably functions as a manganese efflux pump
BMD_5151	COG0009	L-threonylcarbamoyladenylate synthase
BMD_5155	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BMD_5158	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BMD_5160	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BMD_5161	COG0191	fructose-bisphosphate aldolase activity
BMD_5162	COG2204	response regulator
BMD_5163	COG4821	SIS domain
BMD_5164	COG0504	CTP synthase activity
BMD_5166	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BMD_5166	COG1703	isobutyryl-CoA mutase activity
BMD_5166	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BMD_5168	COG1960	acyl-CoA dehydrogenase activity
BMD_5169	COG1960	acyl-CoA dehydrogenase activity
BMD_5170	COG1250	3-hydroxyacyl-CoA dehydrogenase
BMD_5171	COG0183	Belongs to the thiolase family
BMD_5172	COG2181	nitrate reductase activity
BMD_5172	COG0247	lactate metabolic process
BMD_5173	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BMD_5175	COG0018	arginyl-trna synthetase
BMD_5176	COG4506	Protein conserved in bacteria
BMD_5177	COG0010	Belongs to the arginase family
BMD_5178	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BMD_5179	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BMD_5181	COG1994	Peptidase M50
BMD_5182	COG1942	4-Oxalocrotonate Tautomerase
BMD_5183	COG3465	dGTPase activity
BMD_5184	COG1078	dGTPase activity
BMD_5185	COG4844	belongs to the
BMD_5187	COG0095	Lipoate-protein ligase
BMD_5188	COG0280	phosphate acetyltransferase
BMD_5190	COG3773	Cell wall hydrolase
BMD_5192	COG2363	Small membrane protein
BMD_5194	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BMD_5196	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BMD_5197	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BMD_5198	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BMD_5198	COG2508	Transcriptional regulator
BMD_5199	COG0686	Belongs to the AlaDH PNT family
BMD_5201	COG0351	phosphomethylpyrimidine kinase
BMD_5202	COG0561	phosphatase activity
BMD_5203	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BMD_5204	COG2190	(PTS) system
BMD_5204	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BMD_5204	COG1263	PTS System
BMD_5206	COG0438	transferase activity, transferring glycosyl groups
BMD_5209	COG2076	Multidrug Resistance protein
BMD_5211	COG0728	peptidoglycan biosynthetic process
BMD_5214	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BMD_5215	COG4988	ABC transporter
BMD_5216	COG1294	oxidase, subunit
BMD_5217	COG1271	oxidase subunit
BMD_5218	COG3610	response to peptide
BMD_5219	COG2966	Psort location CytoplasmicMembrane, score
BMD_5220	COG1609	Transcriptional regulator
BMD_5222	COG2814	Major facilitator Superfamily
BMD_5225	COG1966	Carbon starvation protein
BMD_5226	COG0753	catalase activity
BMD_5227	COG5002	protein histidine kinase activity
BMD_5230	COG0471	metal ion transport
BMD_5231	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BMD_5234	COG5002	protein histidine kinase activity
BMD_5234	COG3850	Histidine kinase
BMD_5237	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BMD_5238	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BMD_5240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BMD_5241	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BMD_5242	COG4853	Protein conserved in bacteria
BMD_5244	COG5002	protein histidine kinase activity
BMD_5245	COG0745	RESPONSE REGULATOR receiver
BMD_5250	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BMD_5251	COG0305	Participates in initiation and elongation during chromosome replication
BMD_5253	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BMD_5255	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BMD_5258	COG0012	GTP binding
BMD_5259	COG4481	Protein conserved in bacteria
BMD_5260	COG0668	transmembrane transport
BMD_5261	COG3949	Membrane
BMD_5263	COG1475	DNA binding
BMD_5264	COG1192	Involved in chromosome partitioning
BMD_5265	COG1475	DNA binding
BMD_5267	COG0445	tRNA wobble uridine modification
BMD_5268	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BMD_5269	COG1847	R3H domain protein
BMD_5270	COG0706	membrane insertase activity
BMD_5271	COG0594	ribonuclease P activity
BMD_5272	COG0230	Belongs to the bacterial ribosomal protein bL34 family