locus-tag	class	description
BUW91_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BUW91_00010	COG0592	DNA-directed DNA polymerase activity
BUW91_00015	COG2501	S4 domain
BUW91_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BUW91_00025	COG0187	DNA topoisomerase II activity
BUW91_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BUW91_00065	COG0516	GMP reductase activity
BUW91_00065	COG0517	IMP dehydrogenase activity
BUW91_00080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BUW91_00095	COG1428	Deoxynucleoside kinase
BUW91_00100	COG1428	Deoxynucleoside kinase
BUW91_00105	COG3858	chitin binding
BUW91_00105	COG1388	LysM domain
BUW91_00110	COG1335	isochorismatase
BUW91_00115	COG0590	tRNA wobble adenosine to inosine editing
BUW91_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BUW91_00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BUW91_00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BUW91_00240	COG1982	Orn Lys Arg decarboxylase major
BUW91_00245	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BUW91_00250	COG3870	Protein conserved in bacteria
BUW91_00255	COG0470	DNA polymerase III
BUW91_00260	COG1774	PSP1 C-terminal conserved region
BUW91_00265	COG4467	Involved in initiation control of chromosome replication
BUW91_00270	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BUW91_00275	COG2827	Endonuclease containing a URI domain
BUW91_00280	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BUW91_00285	COG2002	toxin-antitoxin pair type II binding
BUW91_00295	COG0084	hydrolase, TatD family'
BUW91_00305	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BUW91_00315	COG4466	Protein conserved in bacteria
BUW91_00330	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BUW91_00335	COG0251	oxidation-reduction process
BUW91_00340	COG2088	sporulation resulting in formation of a cellular spore
BUW91_00345	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BUW91_00350	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BUW91_00355	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BUW91_00360	COG0193	aminoacyl-tRNA hydrolase activity
BUW91_00370	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BUW91_00380	COG2002	toxin-antitoxin pair type II binding
BUW91_00385	COG2244	polysaccharide biosynthetic process
BUW91_00390	COG3956	TIGRFAM MazG family protein
BUW91_00395	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BUW91_00410	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BUW91_00415	COG1098	S1 RNA binding domain
BUW91_00435	COG2304	oxidoreductase activity
BUW91_00440	COG0515	serine threonine protein kinase
BUW91_00445	COG0037	tRNA processing
BUW91_00455	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BUW91_00460	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BUW91_00465	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BUW91_00470	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BUW91_00475	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BUW91_00480	COG0512	Glutamine amidotransferase of anthranilate synthase
BUW91_00485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BUW91_00490	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BUW91_00495	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BUW91_00500	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BUW91_00525	COG3880	PFAM UvrB UvrC protein
BUW91_00530	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BUW91_00535	COG0542	response to heat
BUW91_00540	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BUW91_00545	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BUW91_00550	COG4956	integral membrane protein (PIN domain superfamily)
BUW91_00555	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BUW91_00570	COG1045	serine acetyltransferase
BUW91_00575	COG0215	cysteine-tRNA ligase activity
BUW91_00585	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BUW91_00590	COG3688	RNA-binding protein containing a PIN domain
BUW91_00600	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BUW91_00605	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BUW91_00610	COG0250	Participates in transcription elongation, termination and antitermination
BUW91_00620	COG0081	regulation of translation
BUW91_00625	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BUW91_00635	COG2813	Specifically methylates the guanine in position
BUW91_00640	COG0085	RNA polymerase activity
BUW91_00650	COG1358	cellular component organization or biogenesis
BUW91_00655	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BUW91_00660	COG0049	tRNA binding
BUW91_00670	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BUW91_00675	COG0051	transcription antitermination factor activity, RNA binding
BUW91_00680	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BUW91_00685	COG0088	Forms part of the polypeptide exit tunnel
BUW91_00690	COG0089	rRNA binding
BUW91_00695	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BUW91_00700	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BUW91_00705	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BUW91_00710	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BUW91_00715	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BUW91_00720	COG0255	Belongs to the universal ribosomal protein uL29 family
BUW91_00725	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BUW91_00730	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BUW91_00745	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BUW91_00765	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BUW91_00770	COG1841	ribosomal large subunit assembly
BUW91_00780	COG0201	protein transport
BUW91_00785	COG0563	adenylate kinase activity
BUW91_00790	COG0024	Methionine aminopeptidase
BUW91_00795	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BUW91_00800	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BUW91_00805	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BUW91_00815	COG0202	RNA polymerase activity
BUW91_00820	COG0203	ribosomal protein L17
BUW91_00825	COG1122	ATPase activity
BUW91_00830	COG1122	ATPase activity
BUW91_00835	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BUW91_00840	COG0101	tRNA pseudouridine synthase activity
BUW91_00845	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BUW91_00860	COG0860	N-Acetylmuramoyl-L-alanine amidase
BUW91_00865	COG0489	protein tyrosine kinase activity
BUW91_00870	COG0583	DNA-binding transcription factor activity
BUW91_00880	COG2194	sulfuric ester hydrolase activity
BUW91_00885	COG0726	polysaccharide deacetylase
BUW91_00970	COG1595	DNA-templated transcription, initiation
BUW91_00975	COG5662	AntiSigma factor
BUW91_00980	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BUW91_00990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BUW91_00995	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BUW91_01010	COG0791	NLP P60 protein
BUW91_01010	COG1388	LysM domain
BUW91_01010	COG3103	Sh3 type 3 domain protein
BUW91_01015	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BUW91_01015	COG2213	PTS system mannitol-specific
BUW91_01020	COG3711	transcriptional antiterminator
BUW91_01025	COG0246	Mannitol dehydrogenase
BUW91_01035	COG1376	ErfK ybiS ycfS ynhG family protein
BUW91_01040	COG1970	mechanosensitive ion channel activity
BUW91_01045	COG1368	sulfuric ester hydrolase activity
BUW91_01060	COG1176	ABC-type spermidine putrescine transport system, permease component I
BUW91_01065	COG1177	transmembrane transport
BUW91_01070	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BUW91_01080	COG0745	RESPONSE REGULATOR receiver
BUW91_01085	COG5002	protein histidine kinase activity
BUW91_01100	COG3976	FMN-binding domain protein
BUW91_01100	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BUW91_01105	COG1181	Belongs to the D-alanine--D-alanine ligase family
BUW91_01110	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BUW91_01115	COG0513	Belongs to the DEAD box helicase family
BUW91_01120	COG4294	response to UV
BUW91_01125	COG0705	Rhomboid family
BUW91_01130	COG0736	holo-[acyl-carrier-protein] synthase activity
BUW91_01135	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BUW91_01140	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BUW91_01145	COG0864	Transcriptional regulator
BUW91_01150	COG2337	Toxic component of a toxin-antitoxin (TA) module
BUW91_01155	COG1366	Belongs to the anti-sigma-factor antagonist family
BUW91_01160	COG1366	Belongs to the anti-sigma-factor antagonist family
BUW91_01165	COG2172	sigma factor antagonist activity
BUW91_01170	COG2208	phosphoserine phosphatase activity
BUW91_01175	COG1366	Belongs to the anti-sigma-factor antagonist family
BUW91_01185	COG1191	sigma factor activity
BUW91_01190	COG2208	phosphoserine phosphatase activity
BUW91_01195	COG2183	response to ionizing radiation
BUW91_01285	COG0802	atpase or kinase
BUW91_01290	COG1214	PFAM Peptidase M22, glycoprotease
BUW91_01295	COG0456	acetyltransferase
BUW91_01305	COG0488	(ABC) transporter
BUW91_01310	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BUW91_01315	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BUW91_01320	COG0805	protein transport
BUW91_01330	COG1266	CAAX protease self-immunity
BUW91_01335	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BUW91_01345	COG0714	Associated with various cellular activities
BUW91_01350	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BUW91_01355	COG1305	Transglutaminase-like
BUW91_01360	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BUW91_01360	COG0519	Catalyzes the synthesis of GMP from XMP
BUW91_01365	COG2252	PERMEase
BUW91_01420	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BUW91_01425	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BUW91_01430	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BUW91_01435	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BUW91_01440	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BUW91_01445	COG0047	phosphoribosylformylglycinamidine synthase activity
BUW91_01450	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BUW91_01455	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BUW91_01460	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BUW91_01465	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BUW91_01470	COG0138	bifunctional purine biosynthesis protein purh
BUW91_01475	COG0151	Belongs to the GarS family
BUW91_01485	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BUW91_01490	COG4496	protein, YerC YecD
BUW91_01495	COG0423	glycine-tRNA ligase activity
BUW91_01505	COG0210	DNA helicase
BUW91_01515	COG4851	CamS sex pheromone cAM373 precursor
BUW91_01525	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BUW91_01530	COG0154	amidase activity
BUW91_01540	COG1597	lipid kinase activity
BUW91_01550	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUW91_01560	COG0166	Belongs to the GPI family
BUW91_01565	COG1744	ABC transporter substrate-binding protein PnrA-like
BUW91_01570	COG3852	Histidine kinase
BUW91_01575	COG0024	Methionine aminopeptidase
BUW91_01590	COG4978	Transcriptional regulator
BUW91_01590	COG0789	Transcriptional regulator
BUW91_01595	COG2814	Major facilitator Superfamily
BUW91_01605	COG1876	peptidase activity
BUW91_01610	COG1126	abc transporter atp-binding protein
BUW91_01615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUW91_01620	COG0765	amino acid transport
BUW91_01625	COG0765	amino acid transport
BUW91_01635	COG2733	membrane
BUW91_01640	COG3212	peptidase
BUW91_01645	COG3212	peptidase
BUW91_01650	COG3850	Histidine kinase
BUW91_01650	COG5002	protein histidine kinase activity
BUW91_01655	COG0745	RESPONSE REGULATOR receiver
BUW91_01660	COG0671	phosphoesterase, PA-phosphatase related
BUW91_01665	COG1764	response to oxidative stress
BUW91_01670	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BUW91_01680	COG2259	Doxx family
BUW91_01685	COG0693	protein deglycase activity
BUW91_01695	COG2318	DinB family
BUW91_01705	COG1115	amino acid carrier protein
BUW91_01720	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BUW91_01725	COG0598	Magnesium transport protein CorA
BUW91_01730	COG3290	protein histidine kinase activity
BUW91_01735	COG4565	transcriptional regulatory protein
BUW91_01750	COG4191	Histidine kinase
BUW91_01755	COG0513	Belongs to the DEAD box helicase family
BUW91_01775	COG4842	Belongs to the WXG100 family
BUW91_01780	COG5417	Belongs to the EsaB family
BUW91_01785	COG4499	WXG100 protein secretion system (Wss), protein YukC
BUW91_01810	COG2356	endonuclease I
BUW91_01820	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BUW91_01835	COG0488	(ABC) transporter
BUW91_01840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BUW91_01845	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BUW91_01855	COG1959	2 iron, 2 sulfur cluster binding
BUW91_01860	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BUW91_01860	COG1017	nitric oxide dioxygenase activity
BUW91_01870	COG0693	protein deglycase activity
BUW91_01875	COG2340	Cysteine-rich secretory protein family
BUW91_01880	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BUW91_01885	COG4840	Belongs to the UPF0435 family
BUW91_01890	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BUW91_01895	COG4980	gas vesicle protein
BUW91_01900	COG1295	ribonuclease BN
BUW91_01905	COG2217	Heavy metal translocating P-type atpase
BUW91_01915	COG0640	Transcriptional regulator
BUW91_01940	COG3871	stress protein (general stress protein 26)
BUW91_01945	COG0387	Pfam Sodium calcium exchanger
BUW91_01955	COG0535	radical SAM domain protein
BUW91_01975	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BUW91_01985	COG1113	amino acid transport
BUW91_02010	COG1090	epimerase
BUW91_02020	COG4221	oxidoreductase activity
BUW91_02040	COG1988	membrane-bound metal-dependent
BUW91_02045	COG1194	a g-specific adenine glycosylase
BUW91_02055	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_02070	COG3557	Belongs to the UPF0374 family
BUW91_02075	COG1132	(ABC) transporter
BUW91_02080	COG4129	membrane
BUW91_02085	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BUW91_02090	COG4555	ABC transporter
BUW91_02110	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BUW91_02115	COG0735	belongs to the Fur family
BUW91_02215	COG3382	B3 4 domain protein
BUW91_02230	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BUW91_02235	COG2766	serine protein kinase
BUW91_02250	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BUW91_02265	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BUW91_02275	COG1968	undecaprenyl-diphosphatase activity
BUW91_02280	COG1301	dicarboxylic acid transport
BUW91_02290	COG0586	Pfam SNARE associated Golgi protein
BUW91_02295	COG2217	Heavy metal translocating P-type atpase
BUW91_02300	COG0531	amino acid
BUW91_02320	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BUW91_02330	COG1175	transmembrane transport
BUW91_02345	COG0584	glycerophosphoryl diester phosphodiesterase
BUW91_02365	COG4948	Mandelate Racemase Muconate Lactonizing
BUW91_02410	COG3583	domain protein
BUW91_02410	COG3584	3D domain protein
BUW91_02415	COG1876	peptidase activity
BUW91_02425	COG3103	Sh3 type 3 domain protein
BUW91_02430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUW91_02430	COG0456	acetyltransferase
BUW91_02440	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BUW91_02460	COG1609	Transcriptional regulator
BUW91_02465	COG2814	Major facilitator Superfamily
BUW91_02470	COG0673	inositol 2-dehydrogenase activity
BUW91_02495	COG1609	Transcriptional regulator
BUW91_02510	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUW91_02515	COG1522	sequence-specific DNA binding
BUW91_02535	COG2814	Major facilitator Superfamily
BUW91_02540	COG1309	transcriptional regulator
BUW91_02545	COG1187	pseudouridine synthase activity
BUW91_02555	COG1942	4-Oxalocrotonate Tautomerase
BUW91_02560	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BUW91_02565	COG0747	negative chemotaxis
BUW91_02580	COG0084	hydrolase, TatD family'
BUW91_02585	COG2962	Rard protein
BUW91_02595	COG0628	permease
BUW91_02610	COG0604	alcohol dehydrogenase
BUW91_02615	COG1620	l-lactate permease
BUW91_02625	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BUW91_02635	COG0564	pseudouridine synthase activity
BUW91_02645	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BUW91_02650	COG1376	ErfK ybiS ycfS ynhG family protein
BUW91_02655	COG3153	acetyltransferase
BUW91_02655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BUW91_02660	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BUW91_02665	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BUW91_02675	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BUW91_02680	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BUW91_02685	COG1268	BioY protein
BUW91_02705	COG1959	2 iron, 2 sulfur cluster binding
BUW91_02710	COG0604	alcohol dehydrogenase
BUW91_02720	COG1126	abc transporter atp-binding protein
BUW91_02725	COG0765	amino acid transport
BUW91_02730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUW91_02735	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BUW91_02740	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BUW91_02750	COG0352	thiamine-phosphate diphosphorylase activity
BUW91_02755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BUW91_02770	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BUW91_02775	COG0351	phosphomethylpyrimidine kinase
BUW91_02790	COG0702	epimerase
BUW91_02810	COG3842	ATPase activity
BUW91_02815	COG2508	Transcriptional regulator
BUW91_02830	COG0189	ligase activity
BUW91_02835	COG0189	ligase activity
BUW91_02845	COG3679	Belongs to the UPF0342 family
BUW91_02850	COG0561	phosphatase activity
BUW91_02855	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BUW91_02860	COG0318	PFAM AMP-dependent synthetase and ligase
BUW91_02865	COG1024	Enoyl-CoA hydratase
BUW91_02880	COG4152	abc transporter atp-binding protein
BUW91_02885	COG1668	transmembrane transport
BUW91_02895	COG3481	metal-dependent phosphohydrolase, HD sub domain
BUW91_02905	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BUW91_02930	COG1846	Transcriptional regulator
BUW91_02945	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BUW91_02950	COG1695	Transcriptional regulator
BUW91_02955	COG2153	protein acetylation
BUW91_02960	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BUW91_02960	COG2755	lipolytic protein G-D-S-L family
BUW91_02965	COG0537	adenosine 5'-monophosphoramidase activity
BUW91_02970	COG1131	(ABC) transporter
BUW91_02975	COG4473	ABC transporter
BUW91_02985	COG1473	amidohydrolase
BUW91_02990	COG0671	phosphoesterase, PA-phosphatase related
BUW91_02995	COG3069	C4-dicarboxylate transmembrane transporter activity
BUW91_03000	COG2329	Antibiotic biosynthesis monooxygenase
BUW91_03005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BUW91_03010	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BUW91_03025	COG1309	transcriptional regulator
BUW91_03040	COG2972	Histidine kinase
BUW91_03055	COG1234	tRNA 3'-trailer cleavage
BUW91_03060	COG0095	Lipoate-protein ligase
BUW91_03065	COG0318	PFAM AMP-dependent synthetase and ligase
BUW91_03070	COG1024	Enoyl-CoA hydratase
BUW91_03185	COG0501	Belongs to the peptidase M48B family
BUW91_03190	COG2224	Isocitrate lyase
BUW91_03200	COG4946	Tricorn protease homolog
BUW91_03200	COG0823	Involved in the tonB-independent uptake of proteins
BUW91_03200	COG1506	peptidase
BUW91_03205	COG0398	Pfam SNARE associated Golgi protein
BUW91_03210	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_03215	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BUW91_03220	COG1074	ATP-dependent DNA helicase activity
BUW91_03225	COG0420	3'-5' exonuclease activity
BUW91_03230	COG0419	ATPase involved in DNA repair
BUW91_03235	COG1403	HNH endonuclease
BUW91_03270	COG2311	Membrane
BUW91_03285	COG0367	asparagine synthase
BUW91_03300	COG1562	ergosterol biosynthetic process
BUW91_03310	COG0366	Alpha amylase catalytic
BUW91_03310	COG1874	Beta-galactosidase
BUW91_03315	COG1609	Transcriptional regulator
BUW91_03320	COG1012	belongs to the aldehyde dehydrogenase family
BUW91_03325	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BUW91_03330	COG4187	Peptidase family M20/M25/M40
BUW91_03335	COG0833	amino acid
BUW91_03345	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_03350	COG1666	GTP binding
BUW91_03355	COG2996	Protein conserved in bacteria
BUW91_03365	COG1307	EDD domain protein, DegV family
BUW91_03370	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUW91_03380	COG0561	phosphatase activity
BUW91_03385	COG2151	metal-sulfur cluster biosynthetic enzyme
BUW91_03390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BUW91_03395	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BUW91_03400	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BUW91_03405	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BUW91_03425	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BUW91_03440	COG0542	response to heat
BUW91_03455	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BUW91_03460	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BUW91_03465	COG2084	Dehydrogenase
BUW91_03475	COG2267	carboxylic ester hydrolase activity
BUW91_03495	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BUW91_03500	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BUW91_03505	COG5504	Zn-dependent protease
BUW91_03510	COG0444	Belongs to the ABC transporter superfamily
BUW91_03515	COG4608	Belongs to the ABC transporter superfamily
BUW91_03525	COG0601	transmembrane transport
BUW91_03540	COG0180	Tryptophanyl-tRNA synthetase
BUW91_03550	COG4166	transmembrane transport
BUW91_03555	COG0601	transmembrane transport
BUW91_03560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BUW91_03565	COG0444	Belongs to the ABC transporter superfamily
BUW91_03570	COG4608	Belongs to the ABC transporter superfamily
BUW91_03575	COG0456	acetyltransferase
BUW91_03580	COG1113	amino acid transport
BUW91_03585	COG0531	amino acid
BUW91_03590	COG1393	Belongs to the ArsC family
BUW91_03595	COG0583	DNA-binding transcription factor activity
BUW91_03610	COG0861	Integral membrane protein TerC family
BUW91_03620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BUW91_03630	COG1164	Oligoendopeptidase f
BUW91_03645	COG2346	COG2346, Truncated hemoglobins
BUW91_03650	COG0741	lytic transglycosylase activity
BUW91_03665	COG2357	RelA SpoT domain protein
BUW91_03670	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BUW91_03675	COG0564	pseudouridine synthase activity
BUW91_03685	COG2239	Acts as a magnesium transporter
BUW91_03690	COG0569	domain protein
BUW91_03690	COG0475	glutathione-regulated potassium exporter activity
BUW91_03740	COG0210	DNA helicase
BUW91_03750	COG2323	membrane
BUW91_03755	COG2153	protein acetylation
BUW91_03765	COG2382	esterase
BUW91_03775	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BUW91_03785	COG1737	Transcriptional regulator
BUW91_03790	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BUW91_03820	COG1522	sequence-specific DNA binding
BUW91_03830	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BUW91_03845	COG3142	Participates in the control of copper homeostasis
BUW91_03850	COG1113	amino acid transport
BUW91_03860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BUW91_03865	COG1309	transcriptional regulator
BUW91_03870	COG3711	transcriptional antiterminator
BUW91_03870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BUW91_03875	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BUW91_03880	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BUW91_03885	COG1447	Phosphotransferase system cellobiose-specific component IIA
BUW91_03890	COG1486	melibiose metabolic process
BUW91_03895	COG3275	phosphorelay sensor kinase activity
BUW91_03900	COG3279	Response regulator of the LytR AlgR family
BUW91_03910	COG1346	cytolysis
BUW91_03920	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BUW91_03925	COG0243	molybdopterin cofactor binding
BUW91_03930	COG2223	nitrite transmembrane transporter activity
BUW91_03950	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BUW91_03975	COG3527	Alpha-acetolactate decarboxylase
BUW91_03980	COG0028	Belongs to the TPP enzyme family
BUW91_03990	COG4895	conserved protein (DUF2196)
BUW91_04000	COG1733	regulation of RNA biosynthetic process
BUW91_04005	COG2814	Major facilitator Superfamily
BUW91_04030	COG3052	prosthetic group binding
BUW91_04045	COG0784	Response regulator, receiver
BUW91_04050	COG4191	Histidine kinase
BUW91_04055	COG2066	Belongs to the glutaminase family
BUW91_04060	COG1115	amino acid carrier protein
BUW91_04065	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BUW91_04075	COG4297	protein containing double-stranded beta helix domain
BUW91_04080	COG0531	amino acid
BUW91_04090	COG1607	acyl-coa hydrolase
BUW91_04095	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BUW91_04110	COG0390	transport system, permease component
BUW91_04115	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BUW91_04130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BUW91_04135	COG1136	(ABC) transporter
BUW91_04140	COG0577	efflux transmembrane transporter activity
BUW91_04150	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BUW91_04170	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BUW91_04175	COG0833	amino acid
BUW91_04185	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BUW91_04190	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BUW91_04200	COG0861	Integral membrane protein TerC family
BUW91_04205	COG1301	dicarboxylic acid transport
BUW91_04210	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BUW91_04215	COG3290	protein histidine kinase activity
BUW91_04255	COG1476	TRANSCRIPTIONal
BUW91_04265	COG1368	sulfuric ester hydrolase activity
BUW91_04280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BUW91_04285	COG2040	homocysteine
BUW91_04295	COG0179	Fumarylacetoacetate (FAA) hydrolase
BUW91_04315	COG2851	Citrate transporter
BUW91_04320	COG3290	protein histidine kinase activity
BUW91_04325	COG4565	transcriptional regulatory protein
BUW91_04330	COG3181	Tripartite tricarboxylate transporter family receptor
BUW91_04340	COG0583	DNA-binding transcription factor activity
BUW91_04345	COG3180	Ammonia monooxygenase
BUW91_04350	COG2226	methyltransferase
BUW91_04360	COG0517	IMP dehydrogenase activity
BUW91_04360	COG4175	Glycine betaine
BUW91_04365	COG2113	Glycine betaine
BUW91_04370	COG1309	transcriptional regulator
BUW91_04390	COG0531	amino acid
BUW91_04395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BUW91_04400	COG1464	Belongs to the NlpA lipoprotein family
BUW91_04405	COG2011	ABC-type metal ion transport system permease component
BUW91_04410	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BUW91_04425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BUW91_04435	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BUW91_04440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BUW91_04445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BUW91_04470	COG1737	Transcriptional regulator
BUW91_04475	COG1263	PTS System
BUW91_04475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUW91_04485	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BUW91_04490	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BUW91_04495	COG1116	anion transmembrane transporter activity
BUW91_04500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BUW91_04505	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BUW91_04520	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BUW91_04525	COG1733	regulation of RNA biosynthetic process
BUW91_04560	COG1511	domain protein
BUW91_04570	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BUW91_04575	COG1733	regulation of RNA biosynthetic process
BUW91_04590	COG1132	(ABC) transporter
BUW91_04595	COG1132	(ABC) transporter
BUW91_04605	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BUW91_04610	COG3162	membrane
BUW91_04620	COG1414	Transcriptional regulator
BUW91_04625	COG0656	L-ascorbic acid biosynthetic process
BUW91_04630	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BUW91_04635	COG1846	Transcriptional regulator
BUW91_04640	COG1566	PFAM secretion protein HlyD family protein
BUW91_04645	COG2814	Major facilitator Superfamily
BUW91_04650	COG0655	NAD(P)H dehydrogenase (quinone) activity
BUW91_04665	COG1609	Transcriptional regulator
BUW91_04670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BUW91_04680	COG1129	ABC transporter
BUW91_04685	COG1172	Belongs to the binding-protein-dependent transport system permease family
BUW91_04690	COG1879	ABC-type sugar transport system periplasmic component
BUW91_04695	COG3584	3D domain protein
BUW91_04695	COG3583	domain protein
BUW91_04705	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BUW91_04710	COG1653	transport
BUW91_04755	COG0745	RESPONSE REGULATOR receiver
BUW91_04760	COG5002	protein histidine kinase activity
BUW91_04795	COG0402	S-adenosylhomocysteine deaminase activity
BUW91_04800	COG2252	PERMEase
BUW91_04810	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BUW91_04815	COG1012	belongs to the aldehyde dehydrogenase family
BUW91_04825	COG0710	3-dehydroquinate dehydratase activity
BUW91_04835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUW91_04835	COG1263	PTS System
BUW91_04840	COG0366	Alpha amylase catalytic
BUW91_04845	COG2188	Transcriptional regulator
BUW91_04855	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BUW91_04860	COG1984	allophanate hydrolase subunit 2
BUW91_04865	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BUW91_04870	COG1914	H( )-stimulated, divalent metal cation uptake system
BUW91_04875	COG1272	protein, Hemolysin III
BUW91_04890	COG0778	Nitroreductase
BUW91_04895	COG0628	permease
BUW91_04920	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BUW91_04925	COG2271	Major facilitator Superfamily
BUW91_04930	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BUW91_04935	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BUW91_04950	COG0402	S-adenosylhomocysteine deaminase activity
BUW91_04955	COG1278	Cold shock
BUW91_04960	COG2910	NAD(P)H-binding
BUW91_04965	COG0673	inositol 2-dehydrogenase activity
BUW91_04970	COG0450	alkyl hydroperoxide reductase
BUW91_04975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUW91_05000	COG2203	Gaf domain
BUW91_05000	COG3706	GGDEF domain
BUW91_05000	COG4251	negative regulation of phosphorylation
BUW91_05000	COG5001	Diguanylate cyclase
BUW91_05005	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BUW91_05010	COG2076	Multidrug Resistance protein
BUW91_05015	COG2076	Multidrug Resistance protein
BUW91_05085	COG1649	PFAM Uncharacterised BCR, COG1649
BUW91_05090	COG1737	Transcriptional regulator
BUW91_05110	COG1486	melibiose metabolic process
BUW91_05120	COG1447	Phosphotransferase system cellobiose-specific component IIA
BUW91_05130	COG2971	BadF BadG BcrA BcrD
BUW91_05135	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BUW91_05140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BUW91_05150	COG3037	sugar-specific permease SgaT UlaA
BUW91_05155	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BUW91_05155	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BUW91_05165	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BUW91_05180	COG1376	ErfK ybiS ycfS ynhG family protein
BUW91_05185	COG4106	trans-aconitate 2-methyltransferase activity
BUW91_05190	COG0583	DNA-binding transcription factor activity
BUW91_05200	COG0667	Aldo Keto reductase
BUW91_05215	COG0154	amidase activity
BUW91_05225	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BUW91_05260	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BUW91_05270	COG1733	regulation of RNA biosynthetic process
BUW91_05285	COG0385	Bile acid
BUW91_05295	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BUW91_05300	COG4191	Histidine kinase
BUW91_05305	COG0784	Response regulator, receiver
BUW91_05320	COG1388	LysM domain
BUW91_05320	COG0791	NLP P60 protein
BUW91_05330	COG2385	sporulation resulting in formation of a cellular spore
BUW91_05335	COG0656	L-ascorbic acid biosynthetic process
BUW91_05350	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BUW91_05355	COG4948	Mandelate Racemase Muconate Lactonizing
BUW91_05390	COG0477	Major facilitator Superfamily
BUW91_05395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BUW91_05405	COG0640	Transcriptional regulator
BUW91_05410	COG5658	integral membrane protein
BUW91_05425	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BUW91_05445	COG1132	(ABC) transporter
BUW91_05455	COG3300	MHYT domain
BUW91_05455	COG5001	Diguanylate cyclase
BUW91_05485	COG2843	Capsule synthesis protein
BUW91_05505	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BUW91_05530	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BUW91_05555	COG1396	sequence-specific DNA binding
BUW91_05560	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BUW91_05570	COG0438	transferase activity, transferring glycosyl groups
BUW91_05570	COG0297	glycogen (starch) synthase activity
BUW91_05580	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BUW91_05585	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BUW91_05590	COG0438	transferase activity, transferring glycosyl groups
BUW91_05595	COG2244	polysaccharide biosynthetic process
BUW91_05605	COG1482	cell wall glycoprotein biosynthetic process
BUW91_05610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BUW91_05615	COG3944	biosynthesis protein
BUW91_05620	COG0489	protein tyrosine kinase activity
BUW91_05625	COG4464	protein tyrosine phosphatase activity
BUW91_05630	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BUW91_05635	COG1316	TRANSCRIPTIONal
BUW91_05645	COG4464	protein tyrosine phosphatase activity
BUW91_05655	COG0028	Belongs to the TPP enzyme family
BUW91_05660	COG0069	glutamate synthase activity
BUW91_05670	COG2084	Dehydrogenase
BUW91_05710	COG4124	Belongs to the glycosyl hydrolase 26 family
BUW91_05740	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BUW91_05745	COG2146	nitrite reductase [NAD(P)H] activity
BUW91_05755	COG2116	formate transmembrane transporter activity
BUW91_05765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BUW91_05770	COG4975	Glucose uptake
BUW91_05785	COG0534	Mate efflux family protein
BUW91_05795	COG1316	TRANSCRIPTIONal
BUW91_05805	COG0598	Magnesium transport protein CorA
BUW91_05840	COG0363	glucosamine-6-phosphate deaminase activity
BUW91_05845	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BUW91_05850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUW91_05850	COG1263	PTS System
BUW91_05850	COG2190	(PTS) system
BUW91_05855	COG1811	Na channel or pump
BUW91_05860	COG3961	Belongs to the TPP enzyme family
BUW91_05895	COG1131	(ABC) transporter
BUW91_05900	COG1253	flavin adenine dinucleotide binding
BUW91_05905	COG0789	Transcriptional regulator
BUW91_05915	COG0346	lactoylglutathione lyase activity
BUW91_05920	COG2105	PFAM AIG2 family protein
BUW91_05920	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BUW91_05980	COG4187	Peptidase family M20/M25/M40
BUW91_05995	COG0456	acetyltransferase
BUW91_05995	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BUW91_06010	COG2252	PERMEase
BUW91_06020	COG3279	Response regulator of the LytR AlgR family
BUW91_06025	COG4555	ABC transporter
BUW91_06030	COG1668	transmembrane transport
BUW91_06040	COG0789	Transcriptional regulator
BUW91_06045	COG1846	Transcriptional regulator
BUW91_06050	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BUW91_06050	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BUW91_06070	COG1785	Belongs to the alkaline phosphatase family
BUW91_06075	COG3279	Response regulator of the LytR AlgR family
BUW91_06080	COG2205	protein histidine kinase activity
BUW91_06080	COG0784	Response regulator, receiver
BUW91_06085	COG0861	Integral membrane protein TerC family
BUW91_06090	COG1191	sigma factor activity
BUW91_06120	COG3243	poly(R)-hydroxyalkanoic acid synthase
BUW91_06125	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BUW91_06135	COG2186	Transcriptional regulator
BUW91_06140	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BUW91_06150	COG0247	lactate metabolic process
BUW91_06155	COG1139	Iron-sulfur cluster binding protein
BUW91_06160	COG1556	Lactate utilization protein
BUW91_06165	COG5002	protein histidine kinase activity
BUW91_06170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BUW91_06175	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BUW91_06180	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BUW91_06185	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BUW91_06190	COG0436	Aminotransferase
BUW91_06195	COG1850	ribulose-bisphosphate carboxylase activity
BUW91_06200	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BUW91_06205	COG0235	Class ii aldolase
BUW91_06210	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BUW91_06220	COG1129	ABC transporter
BUW91_06225	COG1172	Belongs to the binding-protein-dependent transport system permease family
BUW91_06250	COG1846	Transcriptional regulator
BUW91_06260	COG4191	Histidine kinase
BUW91_06270	COG0542	response to heat
BUW91_06285	COG0300	oxidoreductase activity
BUW91_06290	COG0697	spore germination
BUW91_06310	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BUW91_06315	COG0720	synthase
BUW91_06325	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BUW91_06330	COG0702	epimerase
BUW91_06340	COG4873	Protein conserved in bacteria
BUW91_06360	COG3773	Cell wall hydrolase
BUW91_06405	COG0646	methionine synthase
BUW91_06405	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BUW91_06410	COG3949	Membrane
BUW91_06420	COG0307	riboflavin synthase, alpha
BUW91_06430	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BUW91_06440	COG3711	transcriptional antiterminator
BUW91_06445	COG2190	(PTS) system
BUW91_06445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUW91_06445	COG1263	PTS System
BUW91_06460	COG1346	cytolysis
BUW91_06470	COG0583	DNA-binding transcription factor activity
BUW91_06485	COG0456	acetyltransferase
BUW91_06490	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_06495	COG0778	Nitroreductase
BUW91_06500	COG0436	Aminotransferase
BUW91_06520	COG0784	Response regulator, receiver
BUW91_06520	COG0835	chemotaxis
BUW91_06530	COG1376	ErfK ybiS ycfS ynhG family protein
BUW91_06550	COG1408	metallophosphoesterase
BUW91_06555	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_06560	COG2200	EAL domain
BUW91_06575	COG4703	Protein of unknown function (DUF1797)
BUW91_06580	COG0517	IMP dehydrogenase activity
BUW91_06585	COG0583	DNA-binding transcription factor activity
BUW91_06590	COG2171	N-acyltransferase activity
BUW91_06595	COG1473	amidohydrolase
BUW91_06605	COG0668	transmembrane transport
BUW91_06610	COG0450	alkyl hydroperoxide reductase
BUW91_06615	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUW91_06620	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BUW91_06630	COG1132	(ABC) transporter
BUW91_06635	COG1132	(ABC) transporter
BUW91_06640	COG0569	domain protein
BUW91_06645	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BUW91_06655	COG0561	phosphatase activity
BUW91_06680	COG0022	dehydrogenase e1 component
BUW91_06685	COG0508	dehydrogenase complex catalyzes the overall conversion of
BUW91_06710	COG1982	Orn Lys Arg decarboxylase major
BUW91_06715	COG4476	Belongs to the UPF0223 family
BUW91_06720	COG4493	Belongs to the UPF0637 family
BUW91_06730	COG0483	inositol monophosphate 1-phosphatase activity
BUW91_06755	COG4896	Protein conserved in bacteria
BUW91_06770	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BUW91_06775	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BUW91_06780	COG4838	Belongs to the UPF0358 family
BUW91_06785	COG0772	Belongs to the SEDS family
BUW91_06790	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BUW91_06795	COG1612	heme a metabolic process
BUW91_06800	COG0109	protoheme IX farnesyltransferase activity
BUW91_06825	COG3336	cytochrome c oxidase
BUW91_06835	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BUW91_06840	COG2340	Cysteine-rich secretory protein family
BUW91_06850	COG2738	Putative neutral zinc metallopeptidase
BUW91_06855	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUW91_06860	COG1694	Mazg nucleotide pyrophosphohydrolase
BUW91_06865	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BUW91_06870	COG1803	Methylglyoxal synthase
BUW91_06875	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BUW91_06880	COG0438	transferase activity, transferring glycosyl groups
BUW91_06885	COG0617	tRNA 3'-terminal CCA addition
BUW91_06890	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BUW91_06890	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BUW91_06900	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BUW91_06905	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BUW91_06910	COG1199	ATP-dependent helicase activity
BUW91_06910	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BUW91_06930	COG0436	Aminotransferase
BUW91_06935	COG0017	Asparaginyl-tRNA synthetase
BUW91_06940	COG3935	DnaD domain protein
BUW91_06945	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BUW91_06955	COG4499	WXG100 protein secretion system (Wss), protein YukC
BUW91_06955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BUW91_06960	COG3331	DNA recombination
BUW91_07000	COG5337	Spore coat protein CotH
BUW91_07015	COG0626	cystathionine gamma-synthase activity
BUW91_07020	COG0626	cystathionine gamma-synthase activity
BUW91_07045	COG1278	Cold shock
BUW91_07055	COG3706	GGDEF domain
BUW91_07065	COG1205	dead DEAH box helicase
BUW91_07065	COG1111	helicase
BUW91_07070	COG3359	exonuclease
BUW91_07080	COG4474	Belongs to the UPF0398 family
BUW91_07085	COG3599	regulation of cell shape
BUW91_07115	COG2197	response regulator
BUW91_07120	COG0366	Alpha amylase catalytic
BUW91_07125	COG0116	Belongs to the methyltransferase superfamily
BUW91_07140	COG1175	transmembrane transport
BUW91_07150	COG3842	ATPase activity
BUW91_07160	COG1199	ATP-dependent helicase activity
BUW91_07165	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BUW91_07170	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BUW91_07175	COG2233	PERMEase
BUW91_07180	COG0583	DNA-binding transcription factor activity
BUW91_07185	COG1012	belongs to the aldehyde dehydrogenase family
BUW91_07195	COG3424	synthase
BUW91_07200	COG1755	Isoprenylcysteine carboxyl methyltransferase
BUW91_07205	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BUW91_07210	COG3541	Predicted nucleotidyltransferase
BUW91_07235	COG0328	RNA-DNA hybrid ribonuclease activity
BUW91_07240	COG0328	RNA-DNA hybrid ribonuclease activity
BUW91_07265	COG2814	Major facilitator Superfamily
BUW91_07275	COG2233	PERMEase
BUW91_07280	COG2362	D-Aminopeptidase
BUW91_07285	COG0601	transmembrane transport
BUW91_07290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BUW91_07295	COG0444	Belongs to the ABC transporter superfamily
BUW91_07300	COG4166	transmembrane transport
BUW91_07305	COG1619	proteins homologs of microcin C7 resistance protein MccF
BUW91_07310	COG0791	NLP P60 protein
BUW91_07315	COG4608	Belongs to the ABC transporter superfamily
BUW91_07335	COG3300	MHYT domain
BUW91_07335	COG5001	Diguanylate cyclase
BUW91_07365	COG2197	response regulator
BUW91_07370	COG4585	Histidine kinase
BUW91_07375	COG3239	Fatty acid desaturase
BUW91_07380	COG2205	protein histidine kinase activity
BUW91_07390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BUW91_07405	COG0791	NLP P60 protein
BUW91_07405	COG1388	LysM domain
BUW91_07410	COG1819	glycosyl
BUW91_07415	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BUW91_07430	COG2814	Major facilitator Superfamily
BUW91_07445	COG3964	amidohydrolase
BUW91_07465	COG2188	Transcriptional regulator
BUW91_07475	COG0434	BtpA family
BUW91_07480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BUW91_07490	COG1785	Belongs to the alkaline phosphatase family
BUW91_07495	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BUW91_07500	COG1404	Belongs to the peptidase S8 family
BUW91_07510	COG1846	Transcriptional regulator
BUW91_07515	COG1566	PFAM secretion protein HlyD family protein
BUW91_07520	COG2814	Major facilitator Superfamily
BUW91_07525	COG1846	Transcriptional regulator
BUW91_07550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BUW91_07555	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BUW91_07560	COG1120	ATPase activity
BUW91_07575	COG2814	Major facilitator Superfamily
BUW91_07595	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BUW91_07600	COG1733	regulation of RNA biosynthetic process
BUW91_07605	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BUW91_07615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BUW91_07625	COG3448	diguanylate cyclase activity
BUW91_07625	COG4175	Glycine betaine
BUW91_07630	COG4176	ABC-type proline glycine betaine transport system permease component
BUW91_07650	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BUW91_07655	COG2208	phosphoserine phosphatase activity
BUW91_07665	COG0531	amino acid
BUW91_07675	COG1011	Hydrolase
BUW91_07680	COG0405	Gamma-glutamyltransferase
BUW91_07685	COG1621	beta-fructofuranosidase activity
BUW91_07690	COG1621	beta-fructofuranosidase activity
BUW91_07695	COG2193	ferroxidase activity
BUW91_07700	COG0477	Major facilitator Superfamily
BUW91_07705	COG0156	8-amino-7-oxononanoate synthase activity
BUW91_07710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BUW91_07720	COG2814	Major facilitator Superfamily
BUW91_07735	COG1012	belongs to the aldehyde dehydrogenase family
BUW91_07740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BUW91_07750	COG1280	lysine exporter protein (LysE YggA)
BUW91_07755	COG1113	amino acid transport
BUW91_07765	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BUW91_07785	COG1113	amino acid transport
BUW91_07805	COG1609	Transcriptional regulator
BUW91_07810	COG2223	nitrite transmembrane transporter activity
BUW91_07820	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BUW91_07825	COG1621	beta-fructofuranosidase activity
BUW91_07830	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BUW91_07830	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BUW91_07835	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BUW91_07840	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUW91_07845	COG3715	PTS system
BUW91_07850	COG3716	PTS system mannose fructose sorbose family IID component
BUW91_07855	COG1621	beta-fructofuranosidase activity
BUW91_07860	COG0765	amino acid transport
BUW91_07865	COG0765	amino acid transport
BUW91_07870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUW91_07875	COG1464	Belongs to the NlpA lipoprotein family
BUW91_07880	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BUW91_07885	COG2011	ABC-type metal ion transport system permease component
BUW91_07905	COG1464	Belongs to the NlpA lipoprotein family
BUW91_07910	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BUW91_07915	COG2011	ABC-type metal ion transport system permease component
BUW91_07920	COG1464	Belongs to the NlpA lipoprotein family
BUW91_07930	COG0024	Methionine aminopeptidase
BUW91_07940	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BUW91_07950	COG0656	L-ascorbic acid biosynthetic process
BUW91_07955	COG2986	histidine ammonia-lyase
BUW91_07965	COG1228	amidohydrolase
BUW91_07970	COG0010	Belongs to the arginase family
BUW91_07975	COG1846	Transcriptional regulator
BUW91_07980	COG1957	nucleoside hydrolase
BUW91_07985	COG0473	3-isopropylmalate dehydrogenase activity
BUW91_07990	COG1288	antiporter activity
BUW91_07995	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BUW91_08025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUW91_08045	COG2364	Membrane
BUW91_08050	COG1846	Transcriptional regulator
BUW91_08055	COG0456	acetyltransferase
BUW91_08095	COG3848	Pyruvate phosphate dikinase
BUW91_08095	COG0574	Belongs to the PEP-utilizing enzyme family
BUW91_08100	COG1309	transcriptional regulator
BUW91_08105	COG2814	Major facilitator Superfamily
BUW91_08110	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BUW91_08115	COG3958	Transketolase
BUW91_08120	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_08125	COG2186	Transcriptional regulator
BUW91_08140	COG0698	ribose 5-phosphate isomerase
BUW91_08165	COG1388	LysM domain
BUW91_08165	COG0791	NLP P60 protein
BUW91_08170	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BUW91_08185	COG2318	DinB family
BUW91_08210	COG0583	DNA-binding transcription factor activity
BUW91_08215	COG0596	Alpha beta hydrolase
BUW91_08245	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_08260	COG3850	Histidine kinase
BUW91_08260	COG5002	protein histidine kinase activity
BUW91_08265	COG0745	RESPONSE REGULATOR receiver
BUW91_08270	COG0586	Pfam SNARE associated Golgi protein
BUW91_08280	COG0726	polysaccharide deacetylase
BUW91_08290	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BUW91_08300	COG0697	spore germination
BUW91_08305	COG4977	sequence-specific DNA binding
BUW91_08330	COG0387	Pfam Sodium calcium exchanger
BUW91_08335	COG0318	PFAM AMP-dependent synthetase and ligase
BUW91_08350	COG1309	transcriptional regulator
BUW91_08355	COG0861	Integral membrane protein TerC family
BUW91_08365	COG5577	PFAM Coat F domain
BUW91_08395	COG3813	Protein conserved in bacteria
BUW91_08420	COG2076	Multidrug Resistance protein
BUW91_08440	COG1278	Cold shock
BUW91_08455	COG1278	Cold shock
BUW91_08470	COG0028	Belongs to the TPP enzyme family
BUW91_08505	COG2172	sigma factor antagonist activity
BUW91_08510	COG1388	LysM domain
BUW91_08510	COG3858	chitin binding
BUW91_08515	COG1376	ErfK ybiS ycfS ynhG family protein
BUW91_08540	COG2226	methyltransferase
BUW91_08550	COG1733	regulation of RNA biosynthetic process
BUW91_08555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BUW91_08570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUW91_08575	COG3420	alginic acid biosynthetic process
BUW91_08590	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BUW91_08595	COG0640	Transcriptional regulator
BUW91_08600	COG0640	Transcriptional regulator
BUW91_08605	COG0346	lactoylglutathione lyase activity
BUW91_08610	COG0475	glutathione-regulated potassium exporter activity
BUW91_08610	COG0589	response to stress
BUW91_08620	COG2076	Multidrug Resistance protein
BUW91_08625	COG2076	Multidrug Resistance protein
BUW91_08670	COG3227	Zinc metalloprotease (Elastase)
BUW91_08685	COG0583	DNA-binding transcription factor activity
BUW91_08690	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BUW91_08700	COG0753	catalase activity
BUW91_08715	COG1366	Belongs to the anti-sigma-factor antagonist family
BUW91_08720	COG1366	Belongs to the anti-sigma-factor antagonist family
BUW91_08740	COG0384	phenazine biosynthesis protein PhzF
BUW91_08750	COG5577	PFAM Coat F domain
BUW91_08760	COG1063	alcohol dehydrogenase
BUW91_08765	COG5577	PFAM Coat F domain
BUW91_08780	COG2814	Major facilitator Superfamily
BUW91_08790	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_08805	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUW91_08820	COG0789	Transcriptional regulator
BUW91_08825	COG1278	Cold shock
BUW91_08875	COG1113	amino acid transport
BUW91_08885	COG2207	Transcriptional regulator
BUW91_08895	COG2376	Dihydroxyacetone kinase
BUW91_08915	COG0745	RESPONSE REGULATOR receiver
BUW91_08920	COG0745	RESPONSE REGULATOR receiver
BUW91_08925	COG5002	protein histidine kinase activity
BUW91_08930	COG0671	phosphoesterase, PA-phosphatase related
BUW91_08940	COG2851	Citrate transporter
BUW91_08990	COG2318	DinB family
BUW91_08995	COG2890	protein-(glutamine-N5) methyltransferase activity
BUW91_09030	COG2311	Membrane
BUW91_09065	COG1114	Component of the transport system for branched-chain amino acids
BUW91_09075	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BUW91_09085	COG4282	regulation of fungal-type cell wall biogenesis
BUW91_09115	COG0574	Belongs to the PEP-utilizing enzyme family
BUW91_09115	COG3848	Pyruvate phosphate dikinase
BUW91_09120	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BUW91_09130	COG0601	transmembrane transport
BUW91_09140	COG0444	Belongs to the ABC transporter superfamily
BUW91_09145	COG4608	Belongs to the ABC transporter superfamily
BUW91_09150	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BUW91_09155	COG0477	Major facilitator Superfamily
BUW91_09175	COG1012	belongs to the aldehyde dehydrogenase family
BUW91_09210	COG0517	IMP dehydrogenase activity
BUW91_09230	COG1309	transcriptional regulator
BUW91_09245	COG1070	Carbohydrate kinase
BUW91_09250	COG0477	Major facilitator Superfamily
BUW91_09250	COG2814	Major facilitator Superfamily
BUW91_09260	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BUW91_09265	COG1845	cytochrome c oxidase, subunit III
BUW91_09275	COG0589	response to stress
BUW91_09280	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_09285	COG1612	heme a metabolic process
BUW91_09290	COG2072	flavoprotein involved in K transport
BUW91_09300	COG2252	PERMEase
BUW91_09310	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BUW91_09315	COG0022	dehydrogenase e1 component
BUW91_09320	COG0508	dehydrogenase complex catalyzes the overall conversion of
BUW91_09325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BUW91_09330	COG3284	Transcriptional regulator
BUW91_09365	COG0628	permease
BUW91_09370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BUW91_09380	COG2211	Major facilitator Superfamily
BUW91_09405	COG0589	response to stress
BUW91_09410	COG5002	protein histidine kinase activity
BUW91_09420	COG1937	Protein conserved in bacteria
BUW91_09425	COG2608	mercury ion transmembrane transporter activity
BUW91_09430	COG2217	Heavy metal translocating P-type atpase
BUW91_09440	COG1388	LysM domain
BUW91_09445	COG2271	Major facilitator Superfamily
BUW91_09475	COG0640	Transcriptional regulator
BUW91_09480	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BUW91_09485	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BUW91_09485	COG0551	DNA topoisomerase type I activity
BUW91_09490	COG5444	nuclease activity
BUW91_09505	COG2050	protein possibly involved in aromatic compounds catabolism
BUW91_09510	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BUW91_09515	COG2323	membrane
BUW91_09530	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BUW91_09535	COG1802	Transcriptional regulator
BUW91_09540	COG0473	3-isopropylmalate dehydrogenase activity
BUW91_09545	COG2814	Major facilitator Superfamily
BUW91_09550	COG1733	regulation of RNA biosynthetic process
BUW91_09555	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BUW91_09555	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BUW91_09560	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BUW91_09560	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BUW91_09585	COG5566	PFAM Mor transcription activator
BUW91_09600	COG0561	phosphatase activity
BUW91_09605	COG1876	peptidase activity
BUW91_09610	COG0726	polysaccharide deacetylase
BUW91_09650	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BUW91_09665	COG0386	Belongs to the glutathione peroxidase family
BUW91_09670	COG1418	mRNA catabolic process
BUW91_09680	COG1413	lyase activity
BUW91_09685	COG0726	polysaccharide deacetylase
BUW91_09695	COG2521	methyltransferase
BUW91_09695	COG2136	Putative SAM-dependent methyltransferase
BUW91_09705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUW91_09710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BUW91_09720	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BUW91_09725	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BUW91_09735	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BUW91_09740	COG0406	alpha-ribazole phosphatase activity
BUW91_09750	COG2096	Adenosyltransferase
BUW91_09755	COG2962	Rard protein
BUW91_09765	COG0523	cobalamin synthesis protein
BUW91_09770	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BUW91_09775	COG0322	excinuclease ABC activity
BUW91_09785	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BUW91_09790	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BUW91_09795	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BUW91_09805	COG3011	Protein conserved in bacteria
BUW91_09810	COG1595	DNA-templated transcription, initiation
BUW91_09830	COG2002	toxin-antitoxin pair type II binding
BUW91_09835	COG0534	Mate efflux family protein
BUW91_09840	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_09865	COG1368	sulfuric ester hydrolase activity
BUW91_09875	COG3853	Toxic anion resistance protein (TelA)
BUW91_09890	COG0726	polysaccharide deacetylase
BUW91_09905	COG5002	protein histidine kinase activity
BUW91_09915	COG1823	symporter activity
BUW91_09920	COG1523	belongs to the glycosyl hydrolase 13 family
BUW91_09925	COG1012	belongs to the aldehyde dehydrogenase family
BUW91_09930	COG2124	cytochrome p450
BUW91_09935	COG2112	serine threonine protein kinase
BUW91_09945	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BUW91_09965	COG3361	conserved protein (COG2071)
BUW91_09970	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BUW91_09975	COG1757	Na H antiporter
BUW91_09985	COG0833	amino acid
BUW91_09990	COG3594	Acyltransferase
BUW91_09995	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BUW91_10000	COG0745	RESPONSE REGULATOR receiver
BUW91_10005	COG5002	protein histidine kinase activity
BUW91_10010	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BUW91_10015	COG3104	oligopeptide transport
BUW91_10025	COG0281	malic enzyme
BUW91_10030	COG3493	citrate carrier protein
BUW91_10035	COG0561	phosphatase activity
BUW91_10040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BUW91_10055	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BUW91_10060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUW91_10065	COG0765	amino acid transport
BUW91_10070	COG0765	amino acid transport
BUW91_10075	COG1126	abc transporter atp-binding protein
BUW91_10080	COG0196	riboflavin kinase activity
BUW91_10085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BUW91_10095	COG0860	N-Acetylmuramoyl-L-alanine amidase
BUW91_10120	COG1070	Carbohydrate kinase
BUW91_10125	COG2140	Oxalate decarboxylase
BUW91_10130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BUW91_10150	COG0363	glucosamine-6-phosphate deaminase activity
BUW91_10180	COG1611	Belongs to the LOG family
BUW91_10185	COG0281	malic enzyme
BUW91_10190	COG3402	PFAM membrane-flanked domain
BUW91_10195	COG3428	Bacterial PH domain
BUW91_10210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BUW91_10215	COG0109	protoheme IX farnesyltransferase activity
BUW91_10220	COG4195	phage-related replication protein
BUW91_10230	COG0789	Transcriptional regulator
BUW91_10265	COG0583	DNA-binding transcription factor activity
BUW91_10270	COG0069	glutamate synthase activity
BUW91_10270	COG0067	glutamate synthase
BUW91_10270	COG0070	glutamate synthase
BUW91_10275	COG0493	'glutamate synthase
BUW91_10295	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BUW91_10310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BUW91_10325	COG1846	Transcriptional regulator
BUW91_10330	COG1380	Effector of murein hydrolase LrgA
BUW91_10335	COG1346	cytolysis
BUW91_10340	COG1366	Belongs to the anti-sigma-factor antagonist family
BUW91_10360	COG0463	Glycosyl transferase, family 2
BUW91_10370	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BUW91_10375	COG0745	RESPONSE REGULATOR receiver
BUW91_10385	COG5583	Uncharacterized small protein (DUF2292)
BUW91_10395	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BUW91_10405	COG4208	sulfate ABC transporter
BUW91_10420	COG0745	RESPONSE REGULATOR receiver
BUW91_10445	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUW91_10455	COG1349	DNA-binding transcription factor activity
BUW91_10460	COG1105	Belongs to the carbohydrate kinase PfkB family
BUW91_10465	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BUW91_10465	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BUW91_10465	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BUW91_10470	COG0527	aspartate kinase activity
BUW91_10480	COG2032	superoxide dismutase activity
BUW91_10485	COG1233	COG1233 Phytoene dehydrogenase and related
BUW91_10495	COG0300	oxidoreductase activity
BUW91_10500	COG0640	Transcriptional regulator
BUW91_10505	COG1012	belongs to the aldehyde dehydrogenase family
BUW91_10510	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BUW91_10525	COG0733	neurotransmitter:sodium symporter activity
BUW91_10535	COG3773	Cell wall hydrolase
BUW91_10555	COG0673	inositol 2-dehydrogenase activity
BUW91_10560	COG1082	Xylose isomerase domain protein TIM barrel
BUW91_10565	COG2094	Belongs to the DNA glycosylase MPG family
BUW91_10575	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BUW91_10585	COG0454	-acetyltransferase
BUW91_10600	COG2814	Major facilitator Superfamily
BUW91_10615	COG3871	stress protein (general stress protein 26)
BUW91_10640	COG1595	DNA-templated transcription, initiation
BUW91_10645	COG4873	Protein conserved in bacteria
BUW91_10650	COG0714	Associated with various cellular activities
BUW91_10655	COG4548	von Willebrand factor, type A
BUW91_10660	COG0697	spore germination
BUW91_10670	COG2207	Transcriptional regulator
BUW91_10675	COG1994	Peptidase M50
BUW91_10680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUW91_10685	COG1119	ATPase activity
BUW91_10700	COG1657	PFAM Prenyltransferase squalene oxidase
BUW91_10710	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BUW91_10710	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BUW91_10720	COG0384	phenazine biosynthesis protein PhzF
BUW91_10735	COG1378	Sugar-specific transcriptional regulator TrmB
BUW91_10740	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BUW91_10745	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_10765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BUW91_10770	COG1279	arginine transmembrane transporter activity
BUW91_10800	COG1396	sequence-specific DNA binding
BUW91_10815	COG0494	nUDIX hydrolase
BUW91_10820	COG1335	isochorismatase
BUW91_10825	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BUW91_10830	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BUW91_10835	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BUW91_10840	COG1098	S1 RNA binding domain
BUW91_10845	COG1404	Belongs to the peptidase S8 family
BUW91_10850	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_10855	COG1254	Belongs to the acylphosphatase family
BUW91_10860	COG2223	nitrite transmembrane transporter activity
BUW91_10865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BUW91_10870	COG4974	Belongs to the 'phage' integrase family
BUW91_10885	COG1396	sequence-specific DNA binding
BUW91_11035	COG4824	toxin secretion phage lysis holin
BUW91_11090	COG2207	Transcriptional regulator
BUW91_11090	COG0662	Cupin 2, conserved barrel domain protein
BUW91_11095	COG0697	spore germination
BUW91_11100	COG0488	(ABC) transporter
BUW91_11105	COG0697	spore germination
BUW91_11130	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BUW91_11135	COG1757	Na H antiporter
BUW91_11140	COG1609	Transcriptional regulator
BUW91_11150	COG1533	DNA photolyase activity
BUW91_11170	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BUW91_11170	COG0551	DNA topoisomerase type I activity
BUW91_11180	COG0446	pyridine nucleotide-disulphide oxidoreductase
BUW91_11230	COG1757	Na H antiporter
BUW91_11255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUW91_11305	COG0514	ATP-dependent DNA helicase (RecQ)
BUW91_11340	COG1575	Belongs to the MenA family. Type 1 subfamily
BUW91_11345	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BUW91_11360	COG2814	Major facilitator Superfamily
BUW91_11365	COG0583	DNA-binding transcription factor activity
BUW91_11370	COG1725	Transcriptional regulator
BUW91_11375	COG1131	(ABC) transporter
BUW91_11385	COG1595	DNA-templated transcription, initiation
BUW91_11400	COG1764	response to oxidative stress
BUW91_11405	COG1846	Transcriptional regulator
BUW91_11420	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
BUW91_11430	COG1388	LysM domain
BUW91_11430	COG3584	3D domain protein
BUW91_11450	COG5002	protein histidine kinase activity
BUW91_11455	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BUW91_11460	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BUW91_11465	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BUW91_11480	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BUW91_11495	COG2409	Drug exporters of the RND superfamily
BUW91_11500	COG1834	amidinotransferase
BUW91_11595	COG0110	maltose O-acetyltransferase activity
BUW91_11600	COG0346	lactoylglutathione lyase activity
BUW91_11610	COG1366	Belongs to the anti-sigma-factor antagonist family
BUW91_11620	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BUW91_11630	COG2176	DNA-directed DNA polymerase activity
BUW91_11645	COG0114	fumarate hydratase activity
BUW91_11655	COG3409	Peptidoglycan-binding domain 1 protein
BUW91_11655	COG3757	hydrolase, family 25
BUW91_11665	COG5002	protein histidine kinase activity
BUW91_11705	COG0778	Nitroreductase
BUW91_11715	COG0300	oxidoreductase activity
BUW91_11720	COG3290	protein histidine kinase activity
BUW91_11725	COG4565	transcriptional regulatory protein
BUW91_11730	COG2851	Citrate transporter
BUW91_11740	COG2610	gluconate transmembrane transporter activity
BUW91_11745	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_11750	COG2195	Cleaves the N-terminal amino acid of tripeptides
BUW91_11780	COG0583	DNA-binding transcription factor activity
BUW91_11790	COG1301	dicarboxylic acid transport
BUW91_11795	COG0019	diaminopimelate decarboxylase activity
BUW91_11805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BUW91_11815	COG4191	Histidine kinase
BUW91_11825	COG1960	acyl-CoA dehydrogenase activity
BUW91_11830	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_11835	COG0318	PFAM AMP-dependent synthetase and ligase
BUW91_11845	COG1250	3-hydroxyacyl-CoA dehydrogenase
BUW91_11850	COG1024	Enoyl-CoA hydratase
BUW91_11865	COG2045	Belongs to the ComB family
BUW91_11870	COG1960	acyl-CoA dehydrogenase activity
BUW91_11875	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_11880	COG1024	Enoyl-CoA hydratase
BUW91_11895	COG1141	Ferredoxin
BUW91_11905	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BUW91_11915	COG0183	Belongs to the thiolase family
BUW91_11920	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BUW91_11945	COG1509	lysine 2,3-aminomutase activity
BUW91_11955	COG0833	amino acid
BUW91_11960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BUW91_11975	COG1979	alcohol dehydrogenase
BUW91_11980	COG0738	Major facilitator superfamily
BUW91_11985	COG1181	Belongs to the D-alanine--D-alanine ligase family
BUW91_12005	COG3977	Valine--pyruvate aminotransferase
BUW91_12010	COG3773	Cell wall hydrolase
BUW91_12035	COG0531	amino acid
BUW91_12040	COG2814	Major facilitator Superfamily
BUW91_12045	COG1846	Transcriptional regulator
BUW91_12050	COG1033	growth of symbiont in host cell
BUW91_12050	COG2409	Drug exporters of the RND superfamily
BUW91_12055	COG2202	Pas domain
BUW91_12055	COG1366	Belongs to the anti-sigma-factor antagonist family
BUW91_12060	COG3832	glyoxalase III activity
BUW91_12065	COG0640	Transcriptional regulator
BUW91_12075	COG2267	carboxylic ester hydrolase activity
BUW91_12085	COG3386	PFAM SMP-30 Gluconolaconase
BUW91_12095	COG2368	4-hydroxyphenylacetate
BUW91_12100	COG3739	integral membrane protein
BUW91_12110	COG0326	Molecular chaperone. Has ATPase activity
BUW91_12115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BUW91_12135	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BUW91_12140	COG3409	Peptidoglycan-binding domain 1 protein
BUW91_12140	COG3757	hydrolase, family 25
BUW91_12150	COG0697	spore germination
BUW91_12155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BUW91_12170	COG4572	Cation transport regulator
BUW91_12175	COG2015	COG2015, Alkyl sulfatase and related hydrolases
BUW91_12180	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BUW91_12195	COG3011	Protein conserved in bacteria
BUW91_12285	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BUW91_12300	COG0494	nUDIX hydrolase
BUW91_12305	COG0702	epimerase
BUW91_12315	COG1846	Transcriptional regulator
BUW91_12320	COG2720	vancomycin resistance protein
BUW91_12325	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BUW91_12350	COG0076	glutamate decarboxylase activity
BUW91_12380	COG2116	formate transmembrane transporter activity
BUW91_12385	COG5609	conserved protein (DUF2294)
BUW91_12400	COG2271	Major facilitator Superfamily
BUW91_12405	COG0277	FAD linked oxidase domain protein
BUW91_12410	COG0840	transmembrane signaling receptor activity
BUW91_12420	COG0622	Phosphoesterase
BUW91_12430	COG1408	metallophosphoesterase
BUW91_12435	COG3663	DNA glycosylase
BUW91_12440	COG3883	PFAM NLP P60 protein
BUW91_12440	COG0791	NLP P60 protein
BUW91_12445	COG1587	Uroporphyrinogen-III synthase
BUW91_12450	COG1414	Transcriptional regulator
BUW91_12455	COG0439	Biotin carboxylase
BUW91_12460	COG0511	ligase activity, forming carbon-carbon bonds
BUW91_12465	COG1984	allophanate hydrolase subunit 2
BUW91_12470	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BUW91_12475	COG4336	lyase activity
BUW91_12480	COG1914	H( )-stimulated, divalent metal cation uptake system
BUW91_12485	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BUW91_12500	COG0318	PFAM AMP-dependent synthetase and ligase
BUW91_12505	COG1268	BioY protein
BUW91_12510	COG0183	Belongs to the thiolase family
BUW91_12530	COG0431	NADPH-dependent FMN reductase
BUW91_12535	COG2197	response regulator
BUW91_12540	COG4585	Histidine kinase
BUW91_12540	COG2203	Gaf domain
BUW91_12560	COG0697	spore germination
BUW91_12570	COG2153	protein acetylation
BUW91_12575	COG0129	dihydroxy-acid dehydratase activity
BUW91_12580	COG2267	carboxylic ester hydrolase activity
BUW91_12585	COG1227	inorganic diphosphatase activity
BUW91_12605	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BUW91_12615	COG0204	Acyl-transferase
BUW91_12620	COG2233	PERMEase
BUW91_12625	COG3195	allantoin biosynthetic process
BUW91_12625	COG3648	Uricase
BUW91_12635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUW91_12650	COG1914	H( )-stimulated, divalent metal cation uptake system
BUW91_12670	COG1846	Transcriptional regulator
BUW91_12680	COG4974	Belongs to the 'phage' integrase family
BUW91_12700	COG4303	Ethanolamine ammonia lyase large subunit
BUW91_12705	COG4819	ethanolamine utilization protein
BUW91_12715	COG0833	amino acid
BUW91_12725	COG1247	-acetyltransferase
BUW91_12730	COG1335	isochorismatase
BUW91_12740	COG3403	YqcI/YcgG family
BUW91_12745	COG1280	lysine exporter protein (LysE YggA)
BUW91_12750	COG2267	carboxylic ester hydrolase activity
BUW91_12755	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BUW91_12760	COG0187	DNA topoisomerase II activity
BUW91_12765	COG1832	CoA-binding protein
BUW91_12770	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BUW91_12775	COG4841	protein insertion into membrane
BUW91_12780	COG0824	Thioesterase
BUW91_12810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUW91_12815	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BUW91_12835	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BUW91_12870	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BUW91_12875	COG2068	MobA-Related Protein
BUW91_12880	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BUW91_12935	COG1183	phosphatidylcholine synthase activity
BUW91_12950	COG2814	Major facilitator Superfamily
BUW91_12955	COG1683	Conserved Protein
BUW91_12960	COG1302	Protein conserved in bacteria
BUW91_12975	COG1295	ribonuclease BN
BUW91_12990	COG2814	Major facilitator Superfamily
BUW91_13000	COG2814	Major facilitator Superfamily
BUW91_13005	COG0789	Transcriptional regulator
BUW91_13015	COG0288	reversible hydration of carbon dioxide
BUW91_13020	COG0659	secondary active sulfate transmembrane transporter activity
BUW91_13025	COG0745	RESPONSE REGULATOR receiver
BUW91_13030	COG5002	protein histidine kinase activity
BUW91_13040	COG0477	Major facilitator Superfamily
BUW91_13045	COG4282	regulation of fungal-type cell wall biogenesis
BUW91_13050	COG0531	amino acid
BUW91_13060	COG0860	N-Acetylmuramoyl-L-alanine amidase
BUW91_13065	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BUW91_13135	COG1363	Peptidase, m42
BUW91_13145	COG1114	Component of the transport system for branched-chain amino acids
BUW91_13165	COG0004	ammonium transporteR
BUW91_13180	COG1252	NADH dehydrogenase
BUW91_13185	COG0679	Auxin Efflux Carrier
BUW91_13190	COG0281	malic enzyme
BUW91_13195	COG1473	amidohydrolase
BUW91_13200	COG2271	Major facilitator Superfamily
BUW91_13220	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BUW91_13225	COG0163	prenyltransferase activity
BUW91_13230	COG0583	DNA-binding transcription factor activity
BUW91_13235	COG0679	Auxin Efflux Carrier
BUW91_13255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BUW91_13260	COG0247	lactate metabolic process
BUW91_13265	COG0277	FAD linked oxidase domain protein
BUW91_13270	COG3835	regulator
BUW91_13275	COG0693	protein deglycase activity
BUW91_13285	COG2610	gluconate transmembrane transporter activity
BUW91_13305	COG1131	(ABC) transporter
BUW91_13315	COG2197	response regulator
BUW91_13350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BUW91_13360	COG0586	Pfam SNARE associated Golgi protein
BUW91_13365	COG1515	deoxyribonuclease V activity
BUW91_13370	COG0584	glycerophosphoryl diester phosphodiesterase
BUW91_13410	COG2849	repeat protein
BUW91_13415	COG5444	nuclease activity
BUW91_13430	COG0534	Mate efflux family protein
BUW91_13435	COG1566	PFAM secretion protein HlyD family protein
BUW91_13445	COG1846	Transcriptional regulator
BUW91_13450	COG0708	Exodeoxyribonuclease III
BUW91_13465	COG0673	inositol 2-dehydrogenase activity
BUW91_13470	COG1349	DNA-binding transcription factor activity
BUW91_13475	COG3853	Toxic anion resistance protein (TelA)
BUW91_13485	COG2310	stress, protein
BUW91_13490	COG2310	stress, protein
BUW91_13495	COG2310	stress, protein
BUW91_13500	COG0737	Belongs to the 5'-nucleotidase family
BUW91_13520	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BUW91_13525	COG1131	(ABC) transporter
BUW91_13535	COG2084	Dehydrogenase
BUW91_13540	COG1278	Cold shock
BUW91_13545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BUW91_13555	COG0028	Belongs to the TPP enzyme family
BUW91_13560	COG1278	Cold shock
BUW91_13590	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_13600	COG0427	acetyl-CoA hydrolase
BUW91_13605	COG3279	Response regulator of the LytR AlgR family
BUW91_13610	COG2323	membrane
BUW91_13615	COG2814	Major facilitator Superfamily
BUW91_13620	COG1388	LysM domain
BUW91_13620	COG3584	3D domain protein
BUW91_13625	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BUW91_13650	COG3340	Belongs to the peptidase S51 family
BUW91_13665	COG0277	FAD linked oxidase domain protein
BUW91_13695	COG2318	DinB family
BUW91_13705	COG0579	oxidoreductase
BUW91_13740	COG1486	melibiose metabolic process
BUW91_13780	COG1929	Belongs to the glycerate kinase type-1 family
BUW91_13785	COG2610	gluconate transmembrane transporter activity
BUW91_13790	COG3835	regulator
BUW91_13795	COG1454	alcohol dehydrogenase
BUW91_13800	COG3152	Membrane
BUW91_13825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUW91_13830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BUW91_13855	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BUW91_13865	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BUW91_13880	COG2390	Transcriptional regulator
BUW91_13910	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BUW91_13915	COG0501	Belongs to the peptidase M48B family
BUW91_13920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BUW91_13925	COG1742	UPF0060 membrane protein
BUW91_13980	COG2391	methyltransferase activity
BUW91_13995	COG1979	alcohol dehydrogenase
BUW91_14000	COG0583	DNA-binding transcription factor activity
BUW91_14010	COG0456	acetyltransferase
BUW91_14040	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_14045	COG1063	alcohol dehydrogenase
BUW91_14070	COG0025	NhaP-type Na H and K H
BUW91_14075	COG1253	flavin adenine dinucleotide binding
BUW91_14085	COG4325	translation initiation factor activity
BUW91_14100	COG4608	Belongs to the ABC transporter superfamily
BUW91_14110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BUW91_14120	COG0747	negative chemotaxis
BUW91_14130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUW91_14150	COG1525	nuclease
BUW91_14160	COG0579	oxidoreductase
BUW91_14165	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BUW91_14170	COG0561	phosphatase activity
BUW91_14185	COG0668	transmembrane transport
BUW91_14215	COG2309	aminopeptidase activity
BUW91_14220	COG1414	Transcriptional regulator
BUW91_14230	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BUW91_14235	COG0277	FAD linked oxidase domain protein
BUW91_14240	COG0247	lactate metabolic process
BUW91_14245	COG0277	FAD linked oxidase domain protein
BUW91_14250	COG1620	l-lactate permease
BUW91_14270	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BUW91_14275	COG1131	(ABC) transporter
BUW91_14295	COG1595	DNA-templated transcription, initiation
BUW91_14315	COG4682	membrane
BUW91_14330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BUW91_14335	COG1366	Belongs to the anti-sigma-factor antagonist family
BUW91_14340	COG0598	Magnesium transport protein CorA
BUW91_14345	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BUW91_14355	COG2323	membrane
BUW91_14360	COG1876	peptidase activity
BUW91_14375	COG5002	protein histidine kinase activity
BUW91_14380	COG0745	RESPONSE REGULATOR receiver
BUW91_14400	COG0508	dehydrogenase complex catalyzes the overall conversion of
BUW91_14405	COG0567	Dehydrogenase, E1 component
BUW91_14415	COG2814	Major facilitator Superfamily
BUW91_14420	COG1764	response to oxidative stress
BUW91_14430	COG2311	Membrane
BUW91_14480	COG0559	Belongs to the binding-protein-dependent transport system permease family
BUW91_14490	COG0347	Belongs to the P(II) protein family
BUW91_14495	COG0004	ammonium transporteR
BUW91_14500	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BUW91_14515	COG0596	Alpha beta hydrolase
BUW91_14535	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BUW91_14535	COG0456	acetyltransferase
BUW91_14540	COG1960	acyl-CoA dehydrogenase activity
BUW91_14580	COG4604	ABC transporter, ATP-binding protein
BUW91_14585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BUW91_14590	COG1492	cobalamin metabolic process
BUW91_14600	COG0531	amino acid
BUW91_14610	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_14615	COG2404	hydrolase activity, acting on ester bonds
BUW91_14630	COG1609	Transcriptional regulator
BUW91_14640	COG2271	Major facilitator Superfamily
BUW91_14645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BUW91_14660	COG1233	COG1233 Phytoene dehydrogenase and related
BUW91_14665	COG0463	Glycosyl transferase, family 2
BUW91_14710	COG0804	urea catabolic process
BUW91_14720	COG0831	urea catabolic process
BUW91_14725	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BUW91_14730	COG1388	LysM domain
BUW91_14730	COG0791	NLP P60 protein
BUW91_14735	COG3584	3D domain protein
BUW91_14735	COG1388	LysM domain
BUW91_14740	COG0778	Nitroreductase
BUW91_14745	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BUW91_14750	COG0586	Pfam SNARE associated Golgi protein
BUW91_14760	COG0400	carboxylic ester hydrolase activity
BUW91_14765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BUW91_14770	COG2244	polysaccharide biosynthetic process
BUW91_14775	COG0697	spore germination
BUW91_14780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BUW91_14800	COG1132	(ABC) transporter
BUW91_14825	COG4195	phage-related replication protein
BUW91_14835	COG0783	Belongs to the Dps family
BUW91_14845	COG5577	PFAM Coat F domain
BUW91_14850	COG1253	flavin adenine dinucleotide binding
BUW91_14865	COG0517	IMP dehydrogenase activity
BUW91_14865	COG0516	GMP reductase activity
BUW91_14875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BUW91_14875	COG0723	plastoquinol--plastocyanin reductase activity
BUW91_14890	COG0287	Prephenate dehydrogenase
BUW91_14900	COG1605	Chorismate mutase
BUW91_14900	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BUW91_14910	COG2059	Chromate
BUW91_14915	COG2059	Chromate
BUW91_14925	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BUW91_14930	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BUW91_14935	COG2508	Transcriptional regulator
BUW91_14940	COG0011	TIGRFAM Protein of
BUW91_14945	COG1388	LysM domain
BUW91_14945	COG0791	NLP P60 protein
BUW91_14950	COG0753	catalase activity
BUW91_14960	COG0733	neurotransmitter:sodium symporter activity
BUW91_15005	COG0730	response to heat
BUW91_15010	COG1902	pentaerythritol trinitrate reductase activity
BUW91_15025	COG2205	protein histidine kinase activity
BUW91_15065	COG0640	Transcriptional regulator
BUW91_15075	COG0778	Nitroreductase
BUW91_15090	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BUW91_15095	COG0860	N-Acetylmuramoyl-L-alanine amidase
BUW91_15095	COG3103	Sh3 type 3 domain protein
BUW91_15095	COG4991	sh3 domain protein
BUW91_15100	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BUW91_15105	COG2002	toxin-antitoxin pair type II binding
BUW91_15110	COG2318	DinB family
BUW91_15115	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BUW91_15125	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BUW91_15130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUW91_15150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUW91_15155	COG1597	lipid kinase activity
BUW91_15165	COG0372	Belongs to the citrate synthase family
BUW91_15170	COG0583	DNA-binding transcription factor activity
BUW91_15175	COG0697	spore germination
BUW91_15180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BUW91_15200	COG1366	Belongs to the anti-sigma-factor antagonist family
BUW91_15200	COG2202	Pas domain
BUW91_15205	COG1366	Belongs to the anti-sigma-factor antagonist family
BUW91_15240	COG2261	transglycosylase associated protein
BUW91_15250	COG0740	serine-type endopeptidase activity
BUW91_15265	COG1027	Aspartate ammonia-lyase
BUW91_15270	COG0252	asparaginase activity
BUW91_15275	COG1396	sequence-specific DNA binding
BUW91_15290	COG0640	Transcriptional regulator
BUW91_15310	COG0531	amino acid
BUW91_15315	COG1959	2 iron, 2 sulfur cluster binding
BUW91_15335	COG0281	malic enzyme
BUW91_15340	COG2746	aminoglycoside 3-N-acetyltransferase activity
BUW91_15350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUW91_15355	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_15370	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BUW91_15380	COG0477	Major facilitator Superfamily
BUW91_15385	COG1846	Transcriptional regulator
BUW91_15390	COG0789	Transcriptional regulator
BUW91_15395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUW91_15430	COG1819	glycosyl
BUW91_15450	COG1902	pentaerythritol trinitrate reductase activity
BUW91_15460	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BUW91_15475	COG2814	Major facilitator Superfamily
BUW91_15485	COG1228	amidohydrolase
BUW91_15495	COG1316	TRANSCRIPTIONal
BUW91_15500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUW91_15520	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BUW91_15535	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BUW91_15595	COG1280	lysine exporter protein (LysE YggA)
BUW91_15605	COG0531	amino acid
BUW91_15620	COG3764	Sortase (surface protein transpeptidase)
BUW91_15625	COG0730	response to heat
BUW91_15635	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BUW91_15645	COG2130	NADP-dependent
BUW91_15670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUW91_15685	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BUW91_15695	COG0501	Belongs to the peptidase M48B family
BUW91_15730	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BUW91_15730	COG0131	Imidazoleglycerol-phosphate dehydratase
BUW91_15745	COG2076	Multidrug Resistance protein
BUW91_15750	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BUW91_15755	COG1278	Cold shock
BUW91_15760	COG2323	membrane
BUW91_15770	COG2910	NAD(P)H-binding
BUW91_15800	COG4607	ABC-type enterochelin transport system periplasmic component
BUW91_15805	COG4604	ABC transporter, ATP-binding protein
BUW91_15810	COG4605	iron ion homeostasis
BUW91_15815	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BUW91_15820	COG3773	Cell wall hydrolase
BUW91_15840	COG1063	alcohol dehydrogenase
BUW91_15845	COG3775	system Galactitol-specific IIC component
BUW91_15850	COG3414	Phosphotransferase system galactitol-specific IIB component
BUW91_15855	COG3414	Phosphotransferase system galactitol-specific IIB component
BUW91_15870	COG2249	NAD(P)H dehydrogenase (quinone) activity
BUW91_15875	COG0681	Belongs to the peptidase S26 family
BUW91_15905	COG1349	DNA-binding transcription factor activity
BUW91_15920	COG1193	negative regulation of DNA recombination
BUW91_15930	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BUW91_15940	COG0861	Integral membrane protein TerC family
BUW91_15945	COG1609	Transcriptional regulator
BUW91_15950	COG1959	2 iron, 2 sulfur cluster binding
BUW91_16010	COG3773	Cell wall hydrolase
BUW91_16015	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BUW91_16045	COG3546	catalase activity
BUW91_16065	COG1280	lysine exporter protein (LysE YggA)
BUW91_16070	COG2207	Transcriptional regulator
BUW91_16070	COG1917	Cupin 2, conserved barrel domain protein
BUW91_16075	COG2203	Gaf domain
BUW91_16075	COG4585	Histidine kinase
BUW91_16095	COG3209	COG3209 Rhs family protein
BUW91_16115	COG1819	glycosyl
BUW91_16120	COG0456	acetyltransferase
BUW91_16135	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BUW91_16145	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BUW91_16165	COG0346	lactoylglutathione lyase activity
BUW91_16170	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BUW91_16185	COG1136	(ABC) transporter
BUW91_16190	COG0577	efflux transmembrane transporter activity
BUW91_16195	COG5002	protein histidine kinase activity
BUW91_16195	COG3850	Histidine kinase
BUW91_16220	COG5002	protein histidine kinase activity
BUW91_16225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUW91_16230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BUW91_16255	COG4989	oxidoreductase activity
BUW91_16265	COG0697	spore germination
BUW91_16270	COG1917	Cupin 2, conserved barrel domain protein
BUW91_16270	COG2207	Transcriptional regulator
BUW91_16345	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BUW91_16355	COG0583	DNA-binding transcription factor activity
BUW91_16365	COG1301	dicarboxylic acid transport
BUW91_16370	COG2824	Alkylphosphonate utilization operon protein PhnA
BUW91_16400	COG0405	Gamma-glutamyltransferase
BUW91_16420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BUW91_16425	COG4521	taurine ABC transporter
BUW91_16430	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BUW91_16435	COG2175	clavaminate synthase activity
BUW91_16440	COG0477	Major facilitator Superfamily
BUW91_16460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BUW91_16470	COG1960	acyl-CoA dehydrogenase activity
BUW91_16475	COG1063	alcohol dehydrogenase
BUW91_16480	COG0745	RESPONSE REGULATOR receiver
BUW91_16485	COG0642	Histidine kinase
BUW91_16490	COG1136	(ABC) transporter
BUW91_16495	COG0577	efflux transmembrane transporter activity
BUW91_16505	COG0412	Dienelactone hydrolase
BUW91_16510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BUW91_16525	COG0730	response to heat
BUW91_16530	COG0425	Belongs to the sulfur carrier protein TusA family
BUW91_16535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BUW91_16535	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BUW91_16540	COG0425	Belongs to the sulfur carrier protein TusA family
BUW91_16540	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BUW91_16555	COG2210	Belongs to the sulfur carrier protein TusA family
BUW91_16560	COG0425	Belongs to the sulfur carrier protein TusA family
BUW91_16565	COG1937	Protein conserved in bacteria
BUW91_16585	COG0583	DNA-binding transcription factor activity
BUW91_16600	COG2188	Transcriptional regulator
BUW91_16610	COG2723	6-phospho-beta-galactosidase activity
BUW91_16635	COG1280	lysine exporter protein (LysE YggA)
BUW91_16650	COG0583	DNA-binding transcription factor activity
BUW91_16655	COG2814	Major facilitator Superfamily
BUW91_16660	COG0346	lactoylglutathione lyase activity
BUW91_16675	COG2723	6-phospho-beta-galactosidase activity
BUW91_16685	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BUW91_16700	COG0778	Nitroreductase
BUW91_16705	COG1012	belongs to the aldehyde dehydrogenase family
BUW91_16725	COG1704	LemA family
BUW91_16745	COG1733	regulation of RNA biosynthetic process
BUW91_16750	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BUW91_16755	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BUW91_16760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUW91_16775	COG2304	oxidoreductase activity
BUW91_16785	COG0346	lactoylglutathione lyase activity
BUW91_16790	COG2808	Putative FMN-binding domain
BUW91_16825	COG4807	Protein conserved in bacteria
BUW91_16835	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BUW91_16845	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUW91_16850	COG1278	Cold shock
BUW91_16855	COG1278	Cold shock
BUW91_16870	COG0747	negative chemotaxis
BUW91_16875	COG0601	transmembrane transport
BUW91_16880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BUW91_16885	COG0444	Belongs to the ABC transporter superfamily
BUW91_16890	COG4608	Belongs to the ABC transporter superfamily
BUW91_16900	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BUW91_16905	COG1301	dicarboxylic acid transport
BUW91_16920	COG0477	Major facilitator Superfamily
BUW91_16965	COG0659	secondary active sulfate transmembrane transporter activity
BUW91_16975	COG2211	Major facilitator Superfamily
BUW91_16980	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
BUW91_16985	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
BUW91_16990	COG1691	(AIR) carboxylase
BUW91_16995	COG1606	tRNA processing
BUW91_17000	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_17010	COG1904	glucuronate isomerase
BUW91_17085	COG0561	phosphatase activity
BUW91_17095	COG2312	Erythromycin esterase
BUW91_17110	COG2329	Antibiotic biosynthesis monooxygenase
BUW91_17150	COG3655	Transcriptional regulator
BUW91_17160	COG0583	DNA-binding transcription factor activity
BUW91_17165	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_17180	COG1609	Transcriptional regulator
BUW91_17185	COG1082	Xylose isomerase domain protein TIM barrel
BUW91_17190	COG0673	inositol 2-dehydrogenase activity
BUW91_17210	COG3718	enzyme involved in inositol metabolism
BUW91_17215	COG3962	Belongs to the TPP enzyme family
BUW91_17220	COG1349	DNA-binding transcription factor activity
BUW91_17225	COG0191	fructose-bisphosphate aldolase activity
BUW91_17230	COG1082	Xylose isomerase domain protein TIM barrel
BUW91_17235	COG2814	Major facilitator Superfamily
BUW91_17255	COG0789	Transcriptional regulator
BUW91_17270	COG0662	Cupin 2, conserved barrel domain protein
BUW91_17290	COG1366	Belongs to the anti-sigma-factor antagonist family
BUW91_17295	COG1278	Cold shock
BUW91_17300	COG1876	peptidase activity
BUW91_17320	COG0598	Magnesium transport protein CorA
BUW91_17325	COG1366	Belongs to the anti-sigma-factor antagonist family
BUW91_17335	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_17345	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_17355	COG4335	DNA alkylation repair
BUW91_17360	COG0454	-acetyltransferase
BUW91_17380	COG2814	Major facilitator Superfamily
BUW91_17385	COG3848	Pyruvate phosphate dikinase
BUW91_17385	COG0574	Belongs to the PEP-utilizing enzyme family
BUW91_17390	COG3848	Pyruvate phosphate dikinase
BUW91_17390	COG0574	Belongs to the PEP-utilizing enzyme family
BUW91_17405	COG2186	Transcriptional regulator
BUW91_17425	COG3619	membrane
BUW91_17430	COG1349	DNA-binding transcription factor activity
BUW91_17435	COG0561	phosphatase activity
BUW91_17445	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BUW91_17460	COG1280	lysine exporter protein (LysE YggA)
BUW91_17475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BUW91_17475	COG3153	acetyltransferase
BUW91_17485	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BUW91_17500	COG2814	Major facilitator Superfamily
BUW91_17505	COG2160	L-arabinose isomerase activity
BUW91_17520	COG1609	Transcriptional regulator
BUW91_17525	COG1078	dGTPase activity
BUW91_17545	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BUW91_17550	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BUW91_17555	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BUW91_17555	COG1918	ferrous iron import across plasma membrane
BUW91_17580	COG1846	Transcriptional regulator
BUW91_17615	COG0697	spore germination
BUW91_17620	COG1388	LysM domain
BUW91_17620	COG0791	NLP P60 protein
BUW91_17625	COG2258	MOSC domain
BUW91_17630	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BUW91_17665	COG4974	Belongs to the 'phage' integrase family
BUW91_17705	COG1309	transcriptional regulator
BUW91_17710	COG3844	kynureninase activity
BUW91_17715	COG1113	amino acid transport
BUW91_17720	COG3483	tryptophan 2,3-dioxygenase activity
BUW91_17725	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BUW91_17730	COG1942	4-Oxalocrotonate Tautomerase
BUW91_17760	COG0251	oxidation-reduction process
BUW91_17775	COG0431	NADPH-dependent FMN reductase
BUW91_17780	COG0196	riboflavin kinase activity
BUW91_17785	COG2368	4-hydroxyphenylacetate
BUW91_17805	COG0789	Transcriptional regulator
BUW91_17840	COG5646	InterPro IPR014922
BUW91_17845	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BUW91_17880	COG2258	MOSC domain
BUW91_17900	COG0477	Major facilitator Superfamily
BUW91_17905	COG0583	DNA-binding transcription factor activity
BUW91_17910	COG2070	2-Nitropropane dioxygenase
BUW91_17915	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BUW91_17930	COG1376	ErfK ybiS ycfS ynhG family protein
BUW91_17960	COG1012	belongs to the aldehyde dehydrogenase family
BUW91_17975	COG1501	Belongs to the glycosyl hydrolase 31 family
BUW91_17985	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BUW91_17995	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BUW91_18005	COG0300	oxidoreductase activity
BUW91_18015	COG0508	dehydrogenase complex catalyzes the overall conversion of
BUW91_18015	COG0596	Alpha beta hydrolase
BUW91_18020	COG1309	transcriptional regulator
BUW91_18025	COG1733	regulation of RNA biosynthetic process
BUW91_18030	COG2249	NAD(P)H dehydrogenase (quinone) activity
BUW91_18035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BUW91_18040	COG2226	methyltransferase
BUW91_18055	COG1942	4-Oxalocrotonate Tautomerase
BUW91_18060	COG0583	DNA-binding transcription factor activity
BUW91_18070	COG1522	sequence-specific DNA binding
BUW91_18080	COG2267	carboxylic ester hydrolase activity
BUW91_18090	COG1335	isochorismatase
BUW91_18100	COG0346	lactoylglutathione lyase activity
BUW91_18105	COG2259	Doxx family
BUW91_18110	COG0039	L-malate dehydrogenase activity
BUW91_18120	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
BUW91_18135	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BUW91_18140	COG1454	alcohol dehydrogenase
BUW91_18140	COG1012	belongs to the aldehyde dehydrogenase family
BUW91_18145	COG4816	utilization protein
BUW91_18150	COG4302	ethanolamine ammonia-lyase activity
BUW91_18155	COG4303	Ethanolamine ammonia lyase large subunit
BUW91_18165	COG4917	ethanolamine utilization protein
BUW91_18170	COG4810	utilization protein
BUW91_18175	COG3192	ethanolamine utilization protein
BUW91_18205	COG1309	transcriptional regulator
BUW91_18210	COG2076	Multidrug Resistance protein
BUW91_18240	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BUW91_18250	COG2851	Citrate transporter
BUW91_18260	COG0477	Major facilitator Superfamily
BUW91_18270	COG0477	Major facilitator Superfamily
BUW91_18275	COG1309	transcriptional regulator
BUW91_18285	COG2318	DinB family
BUW91_18290	COG0156	8-amino-7-oxononanoate synthase activity
BUW91_18295	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BUW91_18310	COG1378	Sugar-specific transcriptional regulator TrmB
BUW91_18315	COG0697	spore germination
BUW91_18325	COG0583	DNA-binding transcription factor activity
BUW91_18365	COG1266	CAAX protease self-immunity
BUW91_18390	COG0252	asparaginase activity
BUW91_18410	COG1695	Transcriptional regulator
BUW91_18415	COG0656	L-ascorbic acid biosynthetic process
BUW91_18425	COG0583	DNA-binding transcription factor activity
BUW91_18435	COG2814	Major facilitator Superfamily
BUW91_18460	COG1309	transcriptional regulator
BUW91_18515	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BUW91_18585	COG3339	Conserved Protein
BUW91_18600	COG3708	Transcriptional regulator
BUW91_18600	COG2207	Transcriptional regulator
BUW91_18615	COG1357	PFAM Pentapeptide repeats (8 copies)
BUW91_18625	COG2249	NAD(P)H dehydrogenase (quinone) activity
BUW91_18630	COG1733	regulation of RNA biosynthetic process
BUW91_18675	COG0303	'Molybdopterin
BUW91_18685	COG0521	Mo-molybdopterin cofactor biosynthetic process
BUW91_18690	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BUW91_18730	COG2828	Protein conserved in bacteria
BUW91_18735	COG0583	DNA-binding transcription factor activity
BUW91_18740	COG2851	Citrate transporter
BUW91_18755	COG0670	Belongs to the BI1 family
BUW91_18775	COG0791	NLP P60 protein
BUW91_18780	COG2814	Major facilitator Superfamily
BUW91_18785	COG1846	Transcriptional regulator
BUW91_18805	COG1278	Cold shock
BUW91_18820	COG1113	amino acid transport
BUW91_18825	COG1113	amino acid transport
BUW91_18830	COG1012	belongs to the aldehyde dehydrogenase family
BUW91_18835	COG0506	proline dehydrogenase activity
BUW91_18840	COG3878	Protein conserved in bacteria
BUW91_18860	COG5001	Diguanylate cyclase
BUW91_18860	COG3300	MHYT domain
BUW91_18910	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BUW91_18915	COG5609	conserved protein (DUF2294)
BUW91_18920	COG3223	Belongs to the PsiE family
BUW91_18925	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BUW91_18950	COG0454	-acetyltransferase
BUW91_18965	COG0789	Transcriptional regulator
BUW91_18970	COG0667	Aldo Keto reductase
BUW91_18980	COG0789	Transcriptional regulator
BUW91_19005	COG1621	beta-fructofuranosidase activity
BUW91_19010	COG4980	gas vesicle protein
BUW91_19035	COG1752	Esterase of the alpha-beta hydrolase superfamily
BUW91_19040	COG0577	efflux transmembrane transporter activity
BUW91_19045	COG1136	(ABC) transporter
BUW91_19055	COG0642	Histidine kinase
BUW91_19060	COG0745	RESPONSE REGULATOR receiver
BUW91_19070	COG1289	transmembrane transporter activity
BUW91_19075	COG1937	Protein conserved in bacteria
BUW91_19080	COG3209	COG3209 Rhs family protein
BUW91_19090	COG3973	AAA domain
BUW91_19095	COG1024	Enoyl-CoA hydratase
BUW91_19100	COG1733	regulation of RNA biosynthetic process
BUW91_19115	COG2124	cytochrome p450
BUW91_19120	COG2259	Doxx family
BUW91_19125	COG0463	Glycosyl transferase, family 2
BUW91_19135	COG0463	Glycosyl transferase, family 2
BUW91_19150	COG1388	LysM domain
BUW91_19150	COG0791	NLP P60 protein
BUW91_19155	COG0840	transmembrane signaling receptor activity
BUW91_19160	COG1846	Transcriptional regulator
BUW91_19175	COG0726	polysaccharide deacetylase
BUW91_19180	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BUW91_19195	COG0833	amino acid
BUW91_19225	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BUW91_19230	COG0569	domain protein
BUW91_19240	COG1522	sequence-specific DNA binding
BUW91_19255	COG0745	RESPONSE REGULATOR receiver
BUW91_19260	COG2770	Histidine kinase
BUW91_19260	COG2205	protein histidine kinase activity
BUW91_19265	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BUW91_19270	COG1607	acyl-coa hydrolase
BUW91_19275	COG1802	Transcriptional regulator
BUW91_19280	COG0697	spore germination
BUW91_19290	COG0006	proline dipeptidase activity
BUW91_19300	COG1316	TRANSCRIPTIONal
BUW91_19310	COG2249	NAD(P)H dehydrogenase (quinone) activity
BUW91_19315	COG5522	Integral membrane protein (intg_mem_TP0381)
BUW91_19320	COG1174	glycine betaine transport
BUW91_19325	COG0517	IMP dehydrogenase activity
BUW91_19325	COG1125	glycine betaine transport
BUW91_19350	COG0395	ABC-type sugar transport system, permease component
BUW91_19375	COG2205	protein histidine kinase activity
BUW91_19380	COG0730	response to heat
BUW91_19385	COG1301	dicarboxylic acid transport
BUW91_19420	COG1316	TRANSCRIPTIONal
BUW91_19425	COG1368	sulfuric ester hydrolase activity
BUW91_19435	COG0697	spore germination
BUW91_19455	COG1113	amino acid transport
BUW91_19460	COG5505	Protein of unknown function (DUF819)
BUW91_19465	COG1309	transcriptional regulator
BUW91_19475	COG0583	DNA-binding transcription factor activity
BUW91_19480	COG0730	response to heat
BUW91_19485	COG1247	-acetyltransferase
BUW91_19490	COG2910	NAD(P)H-binding
BUW91_19495	COG1285	pathogenesis
BUW91_19500	COG2226	methyltransferase
BUW91_19505	COG4195	phage-related replication protein
BUW91_19510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BUW91_19525	COG1113	amino acid transport
BUW91_19555	COG0463	Glycosyl transferase, family 2
BUW91_19585	COG2514	catechol 2,3-dioxygenase activity
BUW91_19605	COG1280	lysine exporter protein (LysE YggA)
BUW91_19625	COG0668	transmembrane transport
BUW91_19630	COG2340	Cysteine-rich secretory protein family
BUW91_19635	COG1253	flavin adenine dinucleotide binding
BUW91_19645	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BUW91_19650	COG0589	response to stress
BUW91_19655	COG0205	6-phosphofructokinase activity
BUW91_19660	COG0791	NLP P60 protein
BUW91_19660	COG1388	LysM domain
BUW91_19670	COG0432	Pfam Uncharacterised protein family UPF0047
BUW91_19675	COG0697	spore germination
BUW91_19680	COG0814	amino acid
BUW91_19705	COG1131	(ABC) transporter
BUW91_19720	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUW91_19735	COG0584	glycerophosphoryl diester phosphodiesterase
BUW91_19745	COG1131	(ABC) transporter
BUW91_19770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUW91_19770	COG1263	PTS System
BUW91_19775	COG3711	transcriptional antiterminator
BUW91_19780	COG2190	(PTS) system
BUW91_19785	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BUW91_19800	COG0772	Belongs to the SEDS family
BUW91_19805	COG0659	secondary active sulfate transmembrane transporter activity
BUW91_19810	COG0813	purine-nucleoside phosphorylase activity
BUW91_19820	COG0671	phosphoesterase, PA-phosphatase related
BUW91_19825	COG4326	sporulation control protein
BUW91_19830	COG0515	serine threonine protein kinase
BUW91_19830	COG2815	serine threonine protein kinase
BUW91_19855	COG4479	Belongs to the UPF0346 family
BUW91_19860	COG3594	Acyltransferase
BUW91_19880	COG0456	acetyltransferase
BUW91_19885	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BUW91_19890	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BUW91_19895	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BUW91_19900	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BUW91_19905	COG1301	dicarboxylic acid transport
BUW91_19915	COG4191	Histidine kinase
BUW91_19940	COG2755	lipolytic protein G-D-S-L family
BUW91_19945	COG1999	signal sequence binding
BUW91_19955	COG1307	EDD domain protein, DegV family
BUW91_19965	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BUW91_19975	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BUW91_19980	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BUW91_19985	COG0788	formyltetrahydrofolate deformylase activity
BUW91_20015	COG0076	glutamate decarboxylase activity
BUW91_20035	COG0415	Belongs to the DNA photolyase family
BUW91_20040	COG3852	Histidine kinase
BUW91_20055	COG1012	belongs to the aldehyde dehydrogenase family
BUW91_20070	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BUW91_20080	COG4846	Membrane protein involved in cytochrome C biogenesis
BUW91_20085	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BUW91_20090	COG0785	Cytochrome C biogenesis protein
BUW91_20100	COG1132	(ABC) transporter
BUW91_20105	COG1132	(ABC) transporter
BUW91_20125	COG4224	UPF0291 protein
BUW91_20130	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BUW91_20155	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BUW91_20160	COG0531	amino acid
BUW91_20170	COG0174	glutamine synthetase
BUW91_20175	COG0789	Transcriptional regulator
BUW91_20180	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BUW91_20185	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BUW91_20190	COG2860	membrane
BUW91_20195	COG0464	growth
BUW91_20215	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BUW91_20220	COG0531	amino acid
BUW91_20230	COG4550	Control of competence regulator ComK, YlbF/YmcA
BUW91_20235	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BUW91_20240	COG1013	pyruvate-flavodoxin oxidoreductase activity
BUW91_20245	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BUW91_20245	COG0674	pyruvate-flavodoxin oxidoreductase activity
BUW91_20255	COG2359	stage V sporulation protein S
BUW91_20260	COG1692	metallophosphoesterase
BUW91_20270	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BUW91_20275	COG1058	Belongs to the CinA family
BUW91_20275	COG1546	Belongs to the CinA family
BUW91_20280	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BUW91_20285	COG1426	Protein conserved in bacteria
BUW91_20300	COG0300	oxidoreductase activity
BUW91_20305	COG0612	Peptidase, M16
BUW91_20310	COG0612	Peptidase, M16
BUW91_20335	COG2188	Transcriptional regulator
BUW91_20345	COG4980	gas vesicle protein
BUW91_20345	COG1674	ftsk spoiiie
BUW91_20355	COG0740	serine-type endopeptidase activity
BUW91_20370	COG0527	aspartate kinase activity
BUW91_20375	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BUW91_20380	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BUW91_20385	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BUW91_20390	COG1873	PFAM PRC-barrel domain
BUW91_20395	COG0612	Peptidase, M16
BUW91_20400	COG0726	polysaccharide deacetylase
BUW91_20405	COG1185	polyribonucleotide nucleotidyltransferase activity
BUW91_20410	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BUW91_20415	COG0196	riboflavin kinase activity
BUW91_20430	COG1550	Protein conserved in bacteria
BUW91_20440	COG1358	cellular component organization or biogenesis
BUW91_20445	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BUW91_20450	COG0195	Participates in both transcription termination and antitermination
BUW91_20455	COG0779	Required for maturation of 30S ribosomal subunits
BUW91_20460	COG2176	DNA-directed DNA polymerase activity
BUW91_20465	COG0442	prolyl-tRNA aminoacylation
BUW91_20470	COG0750	zinc metalloprotease
BUW91_20480	COG4589	Belongs to the CDS family
BUW91_20490	COG0233	cytoplasmic translational termination
BUW91_20495	COG0528	UMP kinase activity
BUW91_20500	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BUW91_20515	COG1191	sigma factor activity
BUW91_20520	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BUW91_20525	COG0835	chemotaxis
BUW91_20530	COG2198	Histidine kinase
BUW91_20530	COG0643	Histidine kinase
BUW91_20535	COG2201	protein-glutamate methylesterase activity
BUW91_20540	COG0455	bacterial-type flagellum organization
BUW91_20545	COG1419	protein localization to endoplasmic reticulum
BUW91_20550	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BUW91_20560	COG1684	flagellar biosynthetic protein fliR
BUW91_20565	COG1987	bacterial-type flagellum assembly
BUW91_20570	COG1338	Plays a role in the flagellum-specific transport system
BUW91_20575	COG3190	flagellar
BUW91_20580	COG2201	protein-glutamate methylesterase activity
BUW91_20585	COG1776	CheC inhibitor of MCP methylation
BUW91_20585	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BUW91_20590	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BUW91_20600	COG1582	Flagellar protein (FlbD)
BUW91_20605	COG4786	Flagellar basal body rod
BUW91_20610	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BUW91_20625	COG2882	bacterial-type flagellum organization
BUW91_20630	COG1157	protein secretion by the type III secretion system
BUW91_20635	COG1317	bacterial-type flagellum organization
BUW91_20640	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BUW91_20645	COG1766	The M ring may be actively involved in energy transduction
BUW91_20650	COG1677	Flagellar hook-basal body complex protein FliE
BUW91_20655	COG1558	bacterial-type flagellum-dependent cell motility
BUW91_20660	COG1815	bacterial-type flagellum-dependent cell motility
BUW91_20665	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BUW91_20670	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BUW91_20680	COG4974	Belongs to the 'phage' integrase family
BUW91_20690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BUW91_20695	COG0758	DNA mediated transformation
BUW91_20700	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BUW91_20705	COG0045	succinate-CoA ligase (ADP-forming) activity
BUW91_20725	COG0335	large ribosomal subunit rRNA binding
BUW91_20735	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BUW91_20745	COG1837	Belongs to the UPF0109 family
BUW91_20750	COG0228	four-way junction DNA binding
BUW91_20755	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BUW91_20765	COG0552	protein localization to endoplasmic reticulum
BUW91_20770	COG1196	nuclear chromosome segregation
BUW91_20780	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BUW91_20785	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_20790	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BUW91_20795	COG0416	fatty acid biosynthetic process
BUW91_20800	COG1349	DNA-binding transcription factor activity
BUW91_20805	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BUW91_20810	COG1760	l-serine dehydratase
BUW91_20815	COG1760	l-serine dehydratase
BUW91_20830	COG1302	Protein conserved in bacteria
BUW91_20835	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BUW91_20845	COG1564	THIamine pyrophosphokinase
BUW91_20850	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BUW91_20855	COG1162	GTPase activity
BUW91_20860	COG2815	serine threonine protein kinase
BUW91_20860	COG0515	serine threonine protein kinase
BUW91_20865	COG0631	protein serine/threonine phosphatase activity
BUW91_20875	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BUW91_20875	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BUW91_20880	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BUW91_20890	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BUW91_20895	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BUW91_20900	COG1758	RNA polymerase activity
BUW91_20905	COG0194	GDP metabolic process
BUW91_20910	COG2052	Domain of unknown function (DUF370)
BUW91_20915	COG1561	YicC-like family, N-terminal region
BUW91_20920	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BUW91_20930	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BUW91_20975	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BUW91_20980	COG0564	pseudouridine synthase activity
BUW91_20985	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BUW91_21000	COG3599	regulation of cell shape
BUW91_21005	COG2302	S4 RNA-binding domain
BUW91_21010	COG0762	integral membrane protein
BUW91_21015	COG1799	cell septum assembly
BUW91_21020	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BUW91_21030	COG1873	PFAM PRC-barrel domain
BUW91_21035	COG1191	sigma factor activity
BUW91_21040	COG1191	sigma factor activity
BUW91_21050	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BUW91_21055	COG0849	cell division
BUW91_21060	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BUW91_21065	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BUW91_21070	COG0772	Belongs to the SEDS family
BUW91_21075	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BUW91_21080	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BUW91_21085	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BUW91_21090	COG0768	penicillin binding
BUW91_21100	COG4839	cell division protein FtsL
BUW91_21110	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BUW91_21120	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BUW91_21125	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BUW91_21130	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BUW91_21135	COG0439	Biotin carboxylase
BUW91_21140	COG0454	-acetyltransferase
BUW91_21150	COG1024	Enoyl-CoA hydratase
BUW91_21155	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BUW91_21160	COG1399	metal-binding, possibly nucleic acid-binding protein
BUW91_21165	COG1323	Belongs to the UPF0348 family
BUW91_21170	COG3480	Lon protease (S16) C-terminal proteolytic domain
BUW91_21175	COG1752	Esterase of the alpha-beta hydrolase superfamily
BUW91_21180	COG3314	Sporulation integral membrane protein YlbJ
BUW91_21185	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BUW91_21190	COG0742	ribosomal rna small subunit methyltransferase
BUW91_21200	COG4471	UPF0298 protein
BUW91_21210	COG3679	Belongs to the UPF0342 family
BUW91_21230	COG4347	Protein of unknown function (DUF1405)
BUW91_21240	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BUW91_21255	COG5582	Belongs to the UPF0302 family
BUW91_21260	COG0457	Tetratricopeptide repeat
BUW91_21270	COG0287	Prephenate dehydrogenase
BUW91_21280	COG0159	tryptophan synthase activity
BUW91_21290	COG0135	phosphoribosylanthranilate isomerase activity
BUW91_21295	COG0134	indole-3-glycerol-phosphate synthase activity
BUW91_21300	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BUW91_21310	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BUW91_21315	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BUW91_21320	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BUW91_21325	COG0105	UTP biosynthetic process
BUW91_21330	COG0142	geranyltranstransferase activity
BUW91_21335	COG2226	methyltransferase
BUW91_21340	COG0142	geranyltranstransferase activity
BUW91_21350	COG0302	gtp cyclohydrolase
BUW91_21355	COG0776	regulation of translation
BUW91_21360	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BUW91_21395	COG2271	Major facilitator Superfamily
BUW91_21400	COG1304	FMN binding
BUW91_21405	COG0539	negative regulation of cytoplasmic translation
BUW91_21415	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BUW91_21425	COG2959	enzyme of heme biosynthesis
BUW91_21430	COG3409	Peptidoglycan-binding domain 1 protein
BUW91_21430	COG3773	Cell wall hydrolase
BUW91_21435	COG2339	peptidase activity
BUW91_21440	COG0252	asparaginase activity
BUW91_21445	COG0492	ferredoxin-NADP+ reductase activity
BUW91_21450	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BUW91_21455	COG4862	establishment of competence for transformation
BUW91_21460	COG0789	Transcriptional regulator
BUW91_21465	COG1408	metallophosphoesterase
BUW91_21480	COG1266	CAAX protease self-immunity
BUW91_21485	COG0514	ATP-dependent DNA helicase (RecQ)
BUW91_21495	COG1141	Ferredoxin
BUW91_21500	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BUW91_21505	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BUW91_21510	COG0739	heme binding
BUW91_21515	COG5002	protein histidine kinase activity
BUW91_21520	COG0745	RESPONSE REGULATOR receiver
BUW91_21525	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BUW91_21530	COG1333	cytochrome c biogenesis protein
BUW91_21535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUW91_21540	COG1187	pseudouridine synthase activity
BUW91_21545	COG0700	Nucleoside recognition
BUW91_21550	COG2715	membrane protein required for spore maturation
BUW91_21555	COG1686	Belongs to the peptidase S11 family
BUW91_21560	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BUW91_21565	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BUW91_21575	COG1547	Domain of unknown function (DUF309)
BUW91_21585	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BUW91_21590	COG4086	secreted protein
BUW91_21600	COG0697	spore germination
BUW91_21615	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BUW91_21650	COG1686	Belongs to the peptidase S11 family
BUW91_21665	COG4974	Belongs to the 'phage' integrase family
BUW91_21675	COG0735	belongs to the Fur family
BUW91_21680	COG1300	Membrane
BUW91_21685	COG0494	nUDIX hydrolase
BUW91_21695	COG0667	Aldo Keto reductase
BUW91_21705	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BUW91_21710	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BUW91_21720	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BUW91_21725	COG1073	alpha beta
BUW91_21740	COG0300	oxidoreductase activity
BUW91_21745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BUW91_21750	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BUW91_21755	COG1902	pentaerythritol trinitrate reductase activity
BUW91_21765	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BUW91_21770	COG1012	belongs to the aldehyde dehydrogenase family
BUW91_21775	COG2508	Transcriptional regulator
BUW91_21795	COG0167	dihydroorotate dehydrogenase activity
BUW91_21795	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BUW91_21800	COG0493	'glutamate synthase
BUW91_21805	COG2195	Cleaves the N-terminal amino acid of tripeptides
BUW91_21810	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BUW91_21815	COG0346	lactoylglutathione lyase activity
BUW91_21820	COG1376	ErfK ybiS ycfS ynhG family protein
BUW91_21825	COG4129	membrane
BUW91_21830	COG1126	abc transporter atp-binding protein
BUW91_21835	COG0765	amino acid transport
BUW91_21840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUW91_21850	COG1703	isobutyryl-CoA mutase activity
BUW91_21855	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BUW91_21855	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BUW91_21865	COG0508	dehydrogenase complex catalyzes the overall conversion of
BUW91_21870	COG0022	dehydrogenase e1 component
BUW91_21875	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BUW91_21895	COG0280	phosphate acetyltransferase
BUW91_21900	COG3829	transcription factor binding
BUW91_21900	COG3290	protein histidine kinase activity
BUW91_21910	COG0584	glycerophosphoryl diester phosphodiesterase
BUW91_21915	COG3093	addiction module antidote protein HigA
BUW91_21920	COG3104	oligopeptide transport
BUW91_21925	COG0745	RESPONSE REGULATOR receiver
BUW91_21930	COG0750	zinc metalloprotease
BUW91_21935	COG0497	DNA recombination
BUW91_21945	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BUW91_21960	COG1722	exodeoxyribonuclease VII activity
BUW91_21970	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BUW91_21975	COG1302	Protein conserved in bacteria
BUW91_21980	COG0439	Biotin carboxylase
BUW91_21985	COG0511	ligase activity, forming carbon-carbon bonds
BUW91_22025	COG3854	ATPases associated with a variety of cellular activities
BUW91_22035	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BUW91_22040	COG0006	proline dipeptidase activity
BUW91_22045	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BUW91_22055	COG3872	metal-dependent enzyme
BUW91_22065	COG1752	Esterase of the alpha-beta hydrolase superfamily
BUW91_22070	COG1321	iron dependent repressor
BUW91_22075	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BUW91_22080	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BUW91_22085	COG0095	Lipoate-protein ligase
BUW91_22090	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BUW91_22100	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BUW91_22105	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BUW91_22110	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BUW91_22140	COG4970	Tfp pilus assembly protein FimT
BUW91_22145	COG4537	Required for transformation and DNA binding
BUW91_22150	COG1459	type II secretion system
BUW91_22155	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BUW91_22160	COG1393	Belongs to the ArsC family
BUW91_22170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BUW91_22185	COG1940	carbohydrate kinase activity
BUW91_22190	COG4483	Protein conserved in bacteria
BUW91_22195	COG0457	Tetratricopeptide repeat
BUW91_22195	COG0705	Rhomboid family
BUW91_22205	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BUW91_22215	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BUW91_22230	COG0704	Plays a role in the regulation of phosphate uptake
BUW91_22245	COG0477	Major facilitator Superfamily
BUW91_22290	COG2814	Major facilitator Superfamily
BUW91_22295	COG1388	LysM domain
BUW91_22300	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BUW91_22305	COG4709	membrane
BUW91_22310	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BUW91_22315	COG0735	belongs to the Fur family
BUW91_22320	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BUW91_22325	COG1121	(ABC) transporter
BUW91_22335	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BUW91_22340	COG0513	Belongs to the DEAD box helicase family
BUW91_22350	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BUW91_22355	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BUW91_22360	COG2384	SAM-dependent methyltransferase
BUW91_22365	COG2010	Cytochrome c
BUW91_22370	COG1960	acyl-CoA dehydrogenase activity
BUW91_22375	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BUW91_22380	COG0358	DNA primase activity
BUW91_22385	COG1671	Belongs to the UPF0178 family
BUW91_22390	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BUW91_22410	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BUW91_22415	COG0295	cytidine deaminase activity
BUW91_22420	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BUW91_22430	COG1480	7TM receptor with intracellular HD hydrolase
BUW91_22435	COG1702	phosphate starvation-inducible protein PhoH
BUW91_22460	COG1030	water channel activity
BUW91_22465	COG1610	YqeY-like protein
BUW91_22470	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BUW91_22475	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BUW91_22480	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BUW91_22485	COG2264	protein methyltransferase activity
BUW91_22500	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BUW91_22505	COG1420	regulation of RNA biosynthetic process
BUW91_22515	COG0481	GTPase activity
BUW91_22525	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BUW91_22530	COG0268	Binds directly to 16S ribosomal RNA
BUW91_22535	COG1466	dna polymerase III delta subunit
BUW91_22545	COG2333	competence protein COMEC
BUW91_22545	COG0658	competence protein
BUW91_22550	COG2131	deaminase
BUW91_22555	COG1555	photosystem II stabilization
BUW91_22555	COG1596	polysaccharide export
BUW91_22560	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BUW91_22565	COG2226	methyltransferase
BUW91_22570	COG0799	negative regulation of ribosome biogenesis
BUW91_22575	COG1713	HD superfamily hydrolase involved in NAD metabolism
BUW91_22580	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BUW91_22585	COG1534	Rna-binding protein
BUW91_22590	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BUW91_22595	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BUW91_22600	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BUW91_22610	COG0688	phosphatidylethanolamine metabolic process
BUW91_22615	COG1183	phosphatidylcholine synthase activity
BUW91_22620	COG1191	sigma factor activity
BUW91_22635	COG0626	cystathionine gamma-synthase activity
BUW91_22640	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BUW91_22645	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BUW91_22650	COG2226	methyltransferase
BUW91_22665	COG0768	penicillin binding
BUW91_22670	COG1335	isochorismatase
BUW91_22675	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BUW91_22680	COG0572	uridine kinase
BUW91_22700	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BUW91_22705	COG3906	Belongs to the UPF0473 family
BUW91_22715	COG4472	Bacterial protein of unknown function (DUF965)
BUW91_22725	COG0628	permease
BUW91_22740	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BUW91_22750	COG0482	sulfurtransferase activity
BUW91_22755	COG1104	cysteine desulfurase activity
BUW91_22760	COG1959	2 iron, 2 sulfur cluster binding
BUW91_22765	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BUW91_22770	COG0581	inorganic phosphate transmembrane transporter activity
BUW91_22775	COG0573	inorganic phosphate transmembrane transporter activity
BUW91_22780	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BUW91_22785	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BUW91_22795	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BUW91_22800	COG0124	histidyl-tRNA synthetase
BUW91_22810	COG0860	N-Acetylmuramoyl-L-alanine amidase
BUW91_22815	COG1490	D-aminoacyl-tRNA deacylase activity
BUW91_22820	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BUW91_22825	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BUW91_22830	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BUW91_22830	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BUW91_22835	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BUW91_22835	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BUW91_22845	COG2244	polysaccharide biosynthetic process
BUW91_22850	COG2323	membrane
BUW91_22860	COG1862	Preprotein translocase
BUW91_22870	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BUW91_22880	COG2255	four-way junction helicase activity
BUW91_22910	COG1388	LysM domain
BUW91_22915	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BUW91_22920	COG0157	Belongs to the NadC ModD family
BUW91_22925	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BUW91_22935	COG1827	regulation of RNA biosynthetic process
BUW91_22940	COG0077	Prephenate dehydratase
BUW91_22945	COG4492	Belongs to the UPF0735 family
BUW91_22950	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BUW91_22970	COG2868	ribosomal protein
BUW91_22980	COG1530	ribonuclease E activity
BUW91_22985	COG1994	Peptidase M50
BUW91_22990	COG0739	heme binding
BUW91_22995	COG2894	cell division
BUW91_23000	COG0850	regulation of cytokinetic process
BUW91_23005	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BUW91_23010	COG1792	Involved in formation and maintenance of cell shape
BUW91_23015	COG1077	Cell shape determining protein MreB Mrl
BUW91_23020	COG2003	Belongs to the UPF0758 family
BUW91_23025	COG0424	maF-like protein
BUW91_23035	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BUW91_23045	COG2322	membrane
BUW91_23050	COG0285	dihydrofolate synthase activity
BUW91_23055	COG0525	valine-tRNA ligase activity
BUW91_23065	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BUW91_23070	COG1388	LysM domain
BUW91_23080	COG0113	porphobilinogen synthase activity
BUW91_23085	COG1587	Uroporphyrinogen-III synthase
BUW91_23090	COG0181	hydroxymethylbilane synthase activity
BUW91_23095	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BUW91_23110	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BUW91_23115	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BUW91_23120	COG1067	ATP-dependent peptidase activity
BUW91_23120	COG0470	DNA polymerase III
BUW91_23125	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BUW91_23130	COG0544	peptidyl-prolyl cis-trans isomerase activity
BUW91_23135	COG0457	Tetratricopeptide repeat
BUW91_23135	COG1477	protein flavinylation
BUW91_23140	COG0066	3-isopropylmalate dehydratase activity
BUW91_23145	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BUW91_23155	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BUW91_23160	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BUW91_23165	COG0440	acetolactate synthase activity
BUW91_23170	COG0028	Belongs to the TPP enzyme family
BUW91_23180	COG0622	Phosphoesterase
BUW91_23195	COG5401	PFAM Sporulation and spore germination
BUW91_23200	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BUW91_23205	COG1846	Transcriptional regulator
BUW91_23215	COG0306	phosphate transporter
BUW91_23220	COG1392	Phosphate transport regulator
BUW91_23225	COG0768	penicillin binding
BUW91_23235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BUW91_23240	COG0431	NADPH-dependent FMN reductase
BUW91_23245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BUW91_23250	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BUW91_23255	COG1116	anion transmembrane transporter activity
BUW91_23260	COG0475	glutathione-regulated potassium exporter activity
BUW91_23265	COG0490	domain, Protein
BUW91_23275	COG2197	response regulator
BUW91_23280	COG0824	Thioesterase
BUW91_23285	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BUW91_23290	COG1053	succinate dehydrogenase
BUW91_23295	COG2009	succinate dehydrogenase
BUW91_23300	COG1719	4-vinyl reductase, 4VR
BUW91_23305	COG0527	aspartate kinase activity
BUW91_23315	COG3118	belongs to the thioredoxin family
BUW91_23320	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BUW91_23325	COG2086	electron transfer activity
BUW91_23330	COG1024	Enoyl-CoA hydratase
BUW91_23335	COG1309	transcriptional regulator
BUW91_23340	COG0318	PFAM AMP-dependent synthetase and ligase
BUW91_23345	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BUW91_23350	COG3766	membrane
BUW91_23355	COG1193	negative regulation of DNA recombination
BUW91_23360	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BUW91_23360	COG1796	DNA polymerase
BUW91_23365	COG1286	toxin biosynthetic process
BUW91_23370	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BUW91_23375	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BUW91_23380	COG0072	phenylalanine-tRNA ligase activity
BUW91_23380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BUW91_23390	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BUW91_23420	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BUW91_23425	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BUW91_23430	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BUW91_23435	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BUW91_23445	COG1484	DNA-dependent DNA replication
BUW91_23450	COG3611	Membrane attachment protein
BUW91_23455	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BUW91_23465	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BUW91_23470	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BUW91_23475	COG0237	dephospho-CoA kinase activity
BUW91_23480	COG1971	Probably functions as a manganese efflux pump
BUW91_23485	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BUW91_23490	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BUW91_23490	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BUW91_23495	COG5002	protein histidine kinase activity
BUW91_23500	COG0745	RESPONSE REGULATOR receiver
BUW91_23510	COG0039	L-malate dehydrogenase activity
BUW91_23515	COG0538	isocitrate dehydrogenase activity
BUW91_23520	COG0372	Belongs to the citrate synthase family
BUW91_23525	COG2707	UPF0756 membrane protein
BUW91_23530	COG0628	permease
BUW91_23535	COG3030	protein affecting phage T7 exclusion by the F plasmid
BUW91_23545	COG0825	malonyl-CoA metabolic process
BUW91_23550	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BUW91_23555	COG2186	Transcriptional regulator
BUW91_23560	COG0281	malic enzyme
BUW91_23565	COG0587	DNA-directed DNA polymerase activity
BUW91_23580	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BUW91_23590	COG4109	DRTGG domain
BUW91_23610	COG0165	Argininosuccinate lyase
BUW91_23615	COG0137	argininosuccinate synthase activity
BUW91_23630	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BUW91_23635	COG0827	DNA restriction-modification system
BUW91_23640	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BUW91_23645	COG3874	Sporulation protein YtfJ
BUW91_23655	COG1714	RDD family
BUW91_23660	COG0616	signal peptide processing
BUW91_23665	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BUW91_23670	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BUW91_23680	COG0301	tRNA thio-modification
BUW91_23685	COG1104	cysteine desulfurase activity
BUW91_23690	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BUW91_23700	COG1309	transcriptional regulator
BUW91_23705	COG1956	GAF domain-containing protein
BUW91_23715	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BUW91_23720	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BUW91_23725	COG0454	-acetyltransferase
BUW91_23730	COG0517	IMP dehydrogenase activity
BUW91_23735	COG0123	including yeast histone deacetylase and acetoin utilization protein
BUW91_23755	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BUW91_23755	COG1605	Chorismate mutase
BUW91_23760	COG3118	belongs to the thioredoxin family
BUW91_23765	COG4980	gas vesicle protein
BUW91_23780	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BUW91_23790	COG1674	ftsk spoiiie
BUW91_23795	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BUW91_23800	COG4848	Belongs to the UPF0354 family
BUW91_23805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUW91_23810	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BUW91_23815	COG1363	Peptidase, m42
BUW91_23820	COG5584	Small secreted protein
BUW91_23825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BUW91_23830	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BUW91_23840	COG0510	thiamine kinase activity
BUW91_23855	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BUW91_23860	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BUW91_23865	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BUW91_23870	COG1349	DNA-binding transcription factor activity
BUW91_23875	COG1187	pseudouridine synthase activity
BUW91_23880	COG2244	polysaccharide biosynthetic process
BUW91_23885	COG2081	HI0933 family
BUW91_23895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BUW91_23900	COG0495	leucyl-tRNA aminoacylation
BUW91_23910	COG2610	gluconate transmembrane transporter activity
BUW91_23915	COG2814	Major facilitator Superfamily
BUW91_23930	COG1242	4 iron, 4 sulfur cluster binding
BUW91_23935	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BUW91_23945	COG2267	carboxylic ester hydrolase activity
BUW91_23950	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BUW91_23955	COG0671	phosphoesterase, PA-phosphatase related
BUW91_23960	COG0438	transferase activity, transferring glycosyl groups
BUW91_23965	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BUW91_23970	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BUW91_23980	COG1506	peptidase
BUW91_23985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BUW91_23995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BUW91_24000	COG0494	nUDIX hydrolase
BUW91_24010	COG4824	toxin secretion phage lysis holin
BUW91_24015	COG0783	Belongs to the Dps family
BUW91_24025	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BUW91_24030	COG0288	reversible hydration of carbon dioxide
BUW91_24035	COG0523	cobalamin synthesis protein
BUW91_24045	COG0254	rRNA binding
BUW91_24050	COG1271	oxidase subunit
BUW91_24055	COG1294	oxidase, subunit
BUW91_24060	COG0716	FMN binding
BUW91_24085	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BUW91_24090	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BUW91_24095	COG4948	Mandelate Racemase Muconate Lactonizing
BUW91_24100	COG0318	PFAM AMP-dependent synthetase and ligase
BUW91_24105	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BUW91_24110	COG0596	Alpha beta hydrolase
BUW91_24115	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BUW91_24120	COG1169	isochorismate synthase
BUW91_24125	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BUW91_24135	COG0058	SHG alpha-glucan phosphorylase activity
BUW91_24140	COG0297	glycogen (starch) synthase activity
BUW91_24145	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BUW91_24280	COG0318	PFAM AMP-dependent synthetase and ligase
BUW91_24285	COG1285	pathogenesis
BUW91_24305	COG0529	Catalyzes the synthesis of activated sulfate
BUW91_24315	COG0306	phosphate transporter
BUW91_24325	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BUW91_24330	COG0346	lactoylglutathione lyase activity
BUW91_24335	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BUW91_24345	COG0166	Belongs to the GPI family
BUW91_24355	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BUW91_24355	COG2111	Na H antiporter
BUW91_24360	COG2111	Na H antiporter
BUW91_24365	COG1006	Multisubunit Na H antiporter MnhC subunit
BUW91_24370	COG0651	ATP synthesis coupled electron transport
BUW91_24375	COG1863	multisubunit Na H antiporter MnhE subunit
BUW91_24380	COG2212	antiporter activity
BUW91_24385	COG1320	monovalent cation:proton antiporter activity
BUW91_24390	COG1979	alcohol dehydrogenase
BUW91_24395	COG2155	Conserved Protein
BUW91_24400	COG1098	S1 RNA binding domain
BUW91_24405	COG0436	Aminotransferase
BUW91_24410	COG1522	sequence-specific DNA binding
BUW91_24415	COG2267	carboxylic ester hydrolase activity
BUW91_24420	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BUW91_24425	COG2032	superoxide dismutase activity
BUW91_24440	COG5018	Exonuclease
BUW91_24445	COG2050	protein possibly involved in aromatic compounds catabolism
BUW91_24455	COG1418	mRNA catabolic process
BUW91_24465	COG2056	Na+-H+ antiporter family
BUW91_24470	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BUW91_24475	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BUW91_24480	COG3584	3D domain protein
BUW91_24490	COG1252	NADH dehydrogenase
BUW91_24495	COG0492	ferredoxin-NADP+ reductase activity
BUW91_24505	COG0316	Belongs to the HesB IscA family
BUW91_24510	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BUW91_24520	COG4844	belongs to the
BUW91_24525	COG1252	NADH dehydrogenase
BUW91_24530	COG4837	Protein of unknown function (DUF1462)
BUW91_24535	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BUW91_24540	COG0083	homoserine kinase activity
BUW91_24545	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BUW91_24550	COG0460	homoserine dehydrogenase
BUW91_24555	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BUW91_24560	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BUW91_24565	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BUW91_24570	COG0647	UMP catabolic process
BUW91_24575	COG2445	Protein of unknown function DUF86
BUW91_24585	COG4470	Protein conserved in bacteria
BUW91_24595	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BUW91_24600	COG0739	heme binding
BUW91_24610	COG0733	neurotransmitter:sodium symporter activity
BUW91_24620	COG3377	Domain of unknown function (DUF1805)
BUW91_24625	COG1801	Protein of unknown function DUF72
BUW91_24630	COG0719	Fe-S assembly protein
BUW91_24635	COG0822	iron-sulfur transferase activity
BUW91_24640	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BUW91_24645	COG0719	Fe-S assembly protein
BUW91_24650	COG0396	ATPase activity
BUW91_24655	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BUW91_24660	COG1464	Belongs to the NlpA lipoprotein family
BUW91_24665	COG2011	ABC-type metal ion transport system permease component
BUW91_24670	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BUW91_24675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUW91_24680	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BUW91_24690	COG0509	glycine decarboxylation via glycine cleavage system
BUW91_24695	COG1393	Belongs to the ArsC family
BUW91_24700	COG1960	acyl-CoA dehydrogenase activity
BUW91_24705	COG0183	Belongs to the thiolase family
BUW91_24710	COG1250	3-hydroxyacyl-CoA dehydrogenase
BUW91_24710	COG1024	Enoyl-CoA hydratase
BUW91_24735	COG1120	ATPase activity
BUW91_24740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BUW91_24745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BUW91_24750	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BUW91_24760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BUW91_24765	COG1309	transcriptional regulator
BUW91_24775	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_24780	COG0477	Major facilitator Superfamily
BUW91_24785	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BUW91_24790	COG0583	DNA-binding transcription factor activity
BUW91_24800	COG0672	)-iron permease
BUW91_24805	COG3850	Histidine kinase
BUW91_24805	COG5002	protein histidine kinase activity
BUW91_24810	COG0745	RESPONSE REGULATOR receiver
BUW91_24815	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BUW91_24820	COG0671	phosphoesterase, PA-phosphatase related
BUW91_24830	COG1846	Transcriptional regulator
BUW91_24835	COG0778	Nitroreductase
BUW91_24840	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BUW91_24845	COG0314	molybdopterin synthase activity
BUW91_24850	COG1763	Mo-molybdopterin cofactor biosynthetic process
BUW91_24855	COG0303	'Molybdopterin
BUW91_24865	COG0746	molybdenum cofactor guanylyltransferase activity
BUW91_24875	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BUW91_24880	COG5609	conserved protein (DUF2294)
BUW91_24885	COG3383	formate dehydrogenase (NAD+) activity
BUW91_24890	COG2427	Protein of unknown function (DUF1641)
BUW91_24895	COG0725	ABC transporter, periplasmic molybdate-binding protein
BUW91_24900	COG4149	molybdate abc transporter
BUW91_24910	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BUW91_24915	COG0557	exoribonuclease II activity
BUW91_24920	COG1647	Serine aminopeptidase, S33
BUW91_24925	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BUW91_24935	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BUW91_24965	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BUW91_24985	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BUW91_24995	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BUW91_25000	COG1660	Displays ATPase and GTPase activities
BUW91_25005	COG1051	belongs to the nudix hydrolase family
BUW91_25010	COG0492	ferredoxin-NADP+ reductase activity
BUW91_25015	COG0457	Tetratricopeptide repeat
BUW91_25020	COG0140	phosphoribosyl-ATP diphosphatase activity
BUW91_25020	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BUW91_25025	COG0107	imidazoleglycerol-phosphate synthase activity
BUW91_25030	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BUW91_25035	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BUW91_25040	COG0131	Imidazoleglycerol-phosphate dehydratase
BUW91_25045	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BUW91_25050	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BUW91_25060	COG0110	maltose O-acetyltransferase activity
BUW91_25065	COG0546	phosphoglycolate phosphatase activity
BUW91_25070	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BUW91_25075	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BUW91_25080	COG1950	PFAM Membrane protein of
BUW91_25085	COG1983	PspC domain protein
BUW91_25090	COG3595	metallopeptidase activity
BUW91_25100	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BUW91_25105	COG0556	nucleotide-excision repair
BUW91_25110	COG2204	response regulator
BUW91_25115	COG1012	belongs to the aldehyde dehydrogenase family
BUW91_25120	COG0506	proline dehydrogenase activity
BUW91_25125	COG4897	Protein conserved in bacteria
BUW91_25130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BUW91_25135	COG0793	Belongs to the peptidase S41A family
BUW91_25135	COG3409	Peptidoglycan-binding domain 1 protein
BUW91_25140	COG0739	heme binding
BUW91_25145	COG2177	Part of the ABC transporter FtsEX involved in
BUW91_25150	COG2884	Cell division ATP-binding protein ftsE
BUW91_25155	COG0655	NAD(P)H dehydrogenase (quinone) activity
BUW91_25165	COG0805	protein transport
BUW91_25170	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BUW91_25185	COG0653	protein targeting
BUW91_25195	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BUW91_25205	COG1516	flagellar protein fliS
BUW91_25210	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BUW91_25220	COG1113	amino acid transport
BUW91_25235	COG1454	alcohol dehydrogenase
BUW91_25240	COG1510	regulation of RNA biosynthetic process
BUW91_25245	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BUW91_25250	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BUW91_25255	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BUW91_25260	COG4786	Flagellar basal body rod
BUW91_25260	COG1256	bacterial-type flagellum assembly
BUW91_25280	COG1040	competence protein
BUW91_25285	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BUW91_25290	COG1307	EDD domain protein, DegV family
BUW91_25295	COG1728	Protein conserved in bacteria
BUW91_25305	COG2197	response regulator
BUW91_25310	COG4585	Histidine kinase
BUW91_25315	COG1739	Uncharacterized protein family UPF0029
BUW91_25320	COG1316	TRANSCRIPTIONal
BUW91_25325	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BUW91_25330	COG1585	Membrane protein implicated in regulation of membrane protease activity
BUW91_25335	COG2268	Band 7 protein
BUW91_25340	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BUW91_25350	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BUW91_25360	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BUW91_25365	COG0791	NLP P60 protein
BUW91_25365	COG1388	LysM domain
BUW91_25370	COG0629	single-stranded DNA binding
BUW91_25395	COG4786	Flagellar basal body rod
BUW91_25400	COG4786	Flagellar basal body rod
BUW91_25405	COG1077	Cell shape determining protein MreB Mrl
BUW91_25410	COG1609	Transcriptional regulator
BUW91_25415	COG0739	heme binding
BUW91_25420	COG2385	sporulation resulting in formation of a cellular spore
BUW91_25435	COG4836	Membrane
BUW91_25440	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BUW91_25445	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BUW91_25450	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BUW91_25455	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BUW91_25460	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BUW91_25465	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BUW91_25470	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BUW91_25475	COG0356	it plays a direct role in the translocation of protons across the membrane
BUW91_25490	COG1404	Belongs to the peptidase S8 family
BUW91_25495	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BUW91_25500	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BUW91_25515	COG0698	ribose 5-phosphate isomerase
BUW91_25525	COG1971	Probably functions as a manganese efflux pump
BUW91_25530	COG0009	L-threonylcarbamoyladenylate synthase
BUW91_25550	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BUW91_25565	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BUW91_25575	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BUW91_25580	COG0191	fructose-bisphosphate aldolase activity
BUW91_25585	COG2204	response regulator
BUW91_25590	COG4821	SIS domain
BUW91_25595	COG0504	CTP synthase activity
BUW91_25605	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BUW91_25605	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BUW91_25605	COG1703	isobutyryl-CoA mutase activity
BUW91_25615	COG1960	acyl-CoA dehydrogenase activity
BUW91_25620	COG1960	acyl-CoA dehydrogenase activity
BUW91_25625	COG1250	3-hydroxyacyl-CoA dehydrogenase
BUW91_25630	COG0183	Belongs to the thiolase family
BUW91_25635	COG2181	nitrate reductase activity
BUW91_25635	COG0247	lactate metabolic process
BUW91_25640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BUW91_25655	COG4506	Protein conserved in bacteria
BUW91_25660	COG0010	Belongs to the arginase family
BUW91_25665	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BUW91_25670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BUW91_25680	COG1994	Peptidase M50
BUW91_25685	COG1942	4-Oxalocrotonate Tautomerase
BUW91_25690	COG3465	dGTPase activity
BUW91_25700	COG4844	belongs to the
BUW91_25710	COG0095	Lipoate-protein ligase
BUW91_25715	COG0280	phosphate acetyltransferase
BUW91_25725	COG3773	Cell wall hydrolase
BUW91_25735	COG2363	Small membrane protein
BUW91_25745	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BUW91_25760	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BUW91_25765	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BUW91_25765	COG2508	Transcriptional regulator
BUW91_25770	COG0686	Belongs to the AlaDH PNT family
BUW91_25780	COG0351	phosphomethylpyrimidine kinase
BUW91_25785	COG0561	phosphatase activity
BUW91_25790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BUW91_25795	COG2190	(PTS) system
BUW91_25795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUW91_25795	COG1263	PTS System
BUW91_25805	COG0438	transferase activity, transferring glycosyl groups
BUW91_25820	COG2076	Multidrug Resistance protein
BUW91_25830	COG0728	peptidoglycan biosynthetic process
BUW91_25845	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BUW91_25850	COG4988	ABC transporter
BUW91_25855	COG1294	oxidase, subunit
BUW91_25860	COG1271	oxidase subunit
BUW91_25865	COG3610	response to peptide
BUW91_25870	COG2966	Psort location CytoplasmicMembrane, score
BUW91_25875	COG1609	Transcriptional regulator
BUW91_25885	COG2814	Major facilitator Superfamily
BUW91_25900	COG1966	Carbon starvation protein
BUW91_25905	COG0753	catalase activity
BUW91_25920	COG0471	metal ion transport
BUW91_25925	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BUW91_25935	COG0745	RESPONSE REGULATOR receiver
BUW91_25955	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BUW91_25960	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BUW91_25975	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BUW91_25980	COG4853	Protein conserved in bacteria
BUW91_25990	COG5002	protein histidine kinase activity
BUW91_25995	COG0745	RESPONSE REGULATOR receiver
BUW91_26020	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BUW91_26025	COG0305	Participates in initiation and elongation during chromosome replication
BUW91_26035	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BUW91_26045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BUW91_26060	COG0012	GTP binding
BUW91_26065	COG4481	Protein conserved in bacteria
BUW91_26070	COG0668	transmembrane transport
BUW91_26085	COG1475	DNA binding
BUW91_26090	COG1192	Involved in chromosome partitioning
BUW91_26095	COG1475	DNA binding
BUW91_26105	COG0445	tRNA wobble uridine modification
BUW91_26110	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BUW91_26115	COG1847	R3H domain protein
BUW91_26120	COG0706	membrane insertase activity
BUW91_26125	COG0594	ribonuclease P activity
BUW91_26130	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BUW91_26135	COG0697	spore germination
BUW91_26145	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BUW91_26150	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BUW91_26155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BUW91_26160	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BUW91_26165	COG1366	Belongs to the anti-sigma-factor antagonist family
BUW91_26180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BUW91_26205	COG1051	belongs to the nudix hydrolase family
BUW91_26210	COG1846	Transcriptional regulator
BUW91_26220	COG1027	Aspartate ammonia-lyase
BUW91_26230	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BUW91_26235	COG5002	protein histidine kinase activity
BUW91_26240	COG0745	RESPONSE REGULATOR receiver
BUW91_26245	COG2351	hydroxyisourate hydrolase activity
BUW91_26375	COG1714	RDD family
BUW91_26410	COG0693	protein deglycase activity
BUW91_26470	COG1131	(ABC) transporter
BUW91_26485	COG1136	(ABC) transporter
BUW91_26490	COG0577	efflux transmembrane transporter activity
BUW91_26500	COG5002	protein histidine kinase activity
BUW91_26520	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BUW91_26530	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BUW91_26535	COG0667	Aldo Keto reductase
BUW91_26545	COG2207	Transcriptional regulator
BUW91_26550	COG1278	Cold shock
BUW91_26565	COG2002	toxin-antitoxin pair type II binding
BUW91_26610	COG0395	ABC-type sugar transport system, permease component
BUW91_26615	COG3250	beta-galactosidase activity
BUW91_26625	COG1609	Transcriptional regulator
BUW91_26630	COG2211	Major facilitator Superfamily
BUW91_26635	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BUW91_26640	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BUW91_26665	COG2814	Major facilitator Superfamily
BUW91_26685	COG1175	transmembrane transport
BUW91_26690	COG0395	ABC-type sugar transport system, permease component
BUW91_26695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BUW91_26700	COG0383	alpha-mannosidase activity
BUW91_26720	COG1940	carbohydrate kinase activity
BUW91_26725	COG1482	cell wall glycoprotein biosynthetic process
BUW91_26730	COG1263	PTS System
BUW91_26730	COG2190	(PTS) system
BUW91_26730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUW91_26735	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BUW91_26740	COG1737	Transcriptional regulator
BUW91_26745	COG0673	inositol 2-dehydrogenase activity
BUW91_26755	COG1649	PFAM Uncharacterised BCR, COG1649
BUW91_26765	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BUW91_26775	COG1486	melibiose metabolic process
BUW91_26790	COG2971	BadF BadG BcrA BcrD
BUW91_26795	COG1737	Transcriptional regulator
BUW91_26805	COG1263	PTS System
BUW91_26805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUW91_26820	COG1349	DNA-binding transcription factor activity
BUW91_26825	COG0805	protein transport
BUW91_26830	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BUW91_26835	COG0402	S-adenosylhomocysteine deaminase activity
BUW91_26840	COG2233	PERMEase
BUW91_26875	COG1309	transcriptional regulator
BUW91_26880	COG2814	Major facilitator Superfamily
BUW91_26935	COG2801	Transposase and inactivated derivatives
BUW91_26945	COG2801	Transposase and inactivated derivatives
BUW91_26955	COG2095	MarC family integral membrane protein
BUW91_26975	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BUW91_27000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BUW91_27010	COG1027	Aspartate ammonia-lyase
BUW91_27020	COG0252	asparaginase activity
BUW91_27040	COG1994	Peptidase M50
BUW91_27045	COG2261	transglycosylase associated protein
BUW91_27050	COG3773	Cell wall hydrolase
BUW91_27060	COG1674	ftsk spoiiie
BUW91_27070	COG2986	histidine ammonia-lyase
BUW91_27075	COG0477	Major facilitator Superfamily
BUW91_27085	COG2271	Major facilitator Superfamily
BUW91_27090	COG0010	Belongs to the arginase family
BUW91_27095	COG1228	amidohydrolase
BUW91_27105	COG2207	Transcriptional regulator
BUW91_27175	COG2318	DinB family
BUW91_27180	COG0697	spore germination
BUW91_27185	COG5553	Cysteine dioxygenase type I
BUW91_27190	COG3344	reverse transcriptase
BUW91_27195	COG1733	regulation of RNA biosynthetic process
BUW91_27200	COG2249	NAD(P)H dehydrogenase (quinone) activity
BUW91_27215	COG0726	polysaccharide deacetylase
BUW91_27245	COG5583	Uncharacterized small protein (DUF2292)
BUW91_27260	COG1376	ErfK ybiS ycfS ynhG family protein
BUW91_27275	COG2814	Major facilitator Superfamily
BUW91_27300	COG0583	DNA-binding transcription factor activity
BUW91_27310	COG1464	Belongs to the NlpA lipoprotein family
BUW91_27315	COG1393	Belongs to the ArsC family
BUW91_27330	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BUW91_27370	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BUW91_27375	COG4191	Histidine kinase
BUW91_27405	COG0604	alcohol dehydrogenase
BUW91_27410	COG1278	Cold shock
BUW91_27435	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BUW91_27480	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BUW91_27495	COG0531	amino acid
BUW91_27510	COG1114	Component of the transport system for branched-chain amino acids
BUW91_27520	COG0531	amino acid
BUW91_27555	COG0318	PFAM AMP-dependent synthetase and ligase
BUW91_27560	COG2072	flavoprotein involved in K transport
BUW91_27575	COG0822	iron-sulfur transferase activity
BUW91_27600	COG1414	Transcriptional regulator
BUW91_27605	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BUW91_27625	COG1473	amidohydrolase
BUW91_27640	COG4948	Mandelate Racemase Muconate Lactonizing
BUW91_27645	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BUW91_27650	COG1554	hydrolase, family 65, central catalytic
BUW91_27655	COG0673	inositol 2-dehydrogenase activity
BUW91_27660	COG1082	Xylose isomerase domain protein TIM barrel
BUW91_27665	COG1063	alcohol dehydrogenase
BUW91_27670	COG0395	ABC-type sugar transport system, permease component
BUW91_27675	COG1175	transmembrane transport
BUW91_27680	COG1653	transport
BUW91_27685	COG0366	Alpha amylase catalytic
BUW91_27690	COG1609	Transcriptional regulator
BUW91_27695	COG1090	epimerase
BUW91_27705	COG1959	2 iron, 2 sulfur cluster binding
BUW91_27715	COG1252	NADH dehydrogenase
BUW91_27780	COG5002	protein histidine kinase activity
BUW91_27785	COG2201	protein-glutamate methylesterase activity
BUW91_27830	COG3505	Type IV secretory pathway VirD4
BUW91_27850	COG0572	uridine kinase
BUW91_27865	COG0741	lytic transglycosylase activity
BUW91_27865	COG0791	NLP P60 protein
BUW91_27985	COG0210	DNA helicase
BUW91_28010	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BUW91_28025	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BUW91_28040	COG0402	S-adenosylhomocysteine deaminase activity
BUW91_28055	COG2188	Transcriptional regulator
BUW91_28065	COG0346	lactoylglutathione lyase activity
BUW91_28070	COG0738	Major facilitator superfamily
BUW91_28075	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BUW91_28105	COG0768	penicillin binding
BUW91_28130	COG0457	Tetratricopeptide repeat
BUW91_28135	COG1063	alcohol dehydrogenase
BUW91_28140	COG2211	Major facilitator Superfamily
BUW91_28145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BUW91_28150	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BUW91_28155	COG1063	alcohol dehydrogenase
BUW91_28170	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_28175	COG4948	Mandelate Racemase Muconate Lactonizing
BUW91_28350	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BUW91_28355	COG2837	iron assimilation
BUW91_28360	COG2822	iron ion transport
BUW91_28365	COG0672	)-iron permease
BUW91_28490	COG1396	sequence-specific DNA binding
BUW91_28610	COG2801	Transposase and inactivated derivatives
BUW91_28635	COG0745	RESPONSE REGULATOR receiver
BUW91_28640	COG2205	protein histidine kinase activity
BUW91_28645	COG1136	(ABC) transporter
BUW91_28650	COG0577	efflux transmembrane transporter activity