locus-tag	class	description
BG04_10	COG0252	asparaginase activity
BG04_1000	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BG04_1001	COG0785	Cytochrome C biogenesis protein
BG04_1003	COG1132	(ABC) transporter
BG04_1004	COG1132	(ABC) transporter
BG04_1008	COG4224	UPF0291 protein
BG04_1009	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BG04_1013	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BG04_1014	COG0531	amino acid
BG04_1016	COG0174	glutamine synthetase
BG04_1017	COG0789	Transcriptional regulator
BG04_1018	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BG04_1019	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BG04_1020	COG2860	membrane
BG04_1021	COG0464	growth
BG04_1023	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BG04_1025	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BG04_1026	COG0531	amino acid
BG04_1028	COG4550	Control of competence regulator ComK, YlbF/YmcA
BG04_1029	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BG04_1030	COG1013	pyruvate-flavodoxin oxidoreductase activity
BG04_1031	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BG04_1031	COG0674	pyruvate-flavodoxin oxidoreductase activity
BG04_1033	COG2359	stage V sporulation protein S
BG04_1034	COG1692	metallophosphoesterase
BG04_1036	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BG04_1037	COG1546	Belongs to the CinA family
BG04_1037	COG1058	Belongs to the CinA family
BG04_1038	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BG04_1039	COG1426	Protein conserved in bacteria
BG04_1042	COG0300	oxidoreductase activity
BG04_1043	COG0612	Peptidase, M16
BG04_1044	COG0612	Peptidase, M16
BG04_1049	COG2188	Transcriptional regulator
BG04_105	COG0131	Imidazoleglycerol-phosphate dehydratase
BG04_105	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BG04_1050	COG4980	gas vesicle protein
BG04_1050	COG1674	ftsk spoiiie
BG04_1052	COG0740	serine-type endopeptidase activity
BG04_1053	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BG04_1055	COG0527	aspartate kinase activity
BG04_1056	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BG04_1057	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BG04_1058	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BG04_1059	COG1873	PFAM PRC-barrel domain
BG04_106	COG1309	transcriptional regulator
BG04_1060	COG0612	Peptidase, M16
BG04_1061	COG0726	polysaccharide deacetylase
BG04_1062	COG1185	polyribonucleotide nucleotidyltransferase activity
BG04_1063	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BG04_1064	COG0196	riboflavin kinase activity
BG04_1067	COG1550	Protein conserved in bacteria
BG04_1069	COG1358	cellular component organization or biogenesis
BG04_107	COG2076	Multidrug Resistance protein
BG04_1070	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BG04_1071	COG0195	Participates in both transcription termination and antitermination
BG04_1072	COG0779	Required for maturation of 30S ribosomal subunits
BG04_1073	COG2176	DNA-directed DNA polymerase activity
BG04_1074	COG0442	prolyl-tRNA aminoacylation
BG04_1075	COG0750	zinc metalloprotease
BG04_1077	COG4589	Belongs to the CDS family
BG04_1079	COG0233	cytoplasmic translational termination
BG04_108	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BG04_1080	COG0528	UMP kinase activity
BG04_1081	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BG04_1084	COG1191	sigma factor activity
BG04_1085	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BG04_1086	COG0835	chemotaxis
BG04_1087	COG0643	Histidine kinase
BG04_1087	COG2198	Histidine kinase
BG04_1088	COG2201	protein-glutamate methylesterase activity
BG04_1089	COG0455	bacterial-type flagellum organization
BG04_109	COG1278	Cold shock
BG04_1090	COG1419	protein localization to endoplasmic reticulum
BG04_1091	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BG04_1092	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BG04_1093	COG1684	flagellar biosynthetic protein fliR
BG04_1094	COG1987	bacterial-type flagellum assembly
BG04_1095	COG1338	Plays a role in the flagellum-specific transport system
BG04_1096	COG3190	flagellar
BG04_1097	COG2201	protein-glutamate methylesterase activity
BG04_1098	COG1776	CheC inhibitor of MCP methylation
BG04_1098	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BG04_1099	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BG04_11	COG1396	sequence-specific DNA binding
BG04_110	COG2323	membrane
BG04_1101	COG1582	Flagellar protein (FlbD)
BG04_1102	COG4786	Flagellar basal body rod
BG04_1103	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BG04_1106	COG2882	bacterial-type flagellum organization
BG04_1107	COG1157	protein secretion by the type III secretion system
BG04_1108	COG1317	bacterial-type flagellum organization
BG04_1109	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BG04_1110	COG1766	The M ring may be actively involved in energy transduction
BG04_1111	COG1677	Flagellar hook-basal body complex protein FliE
BG04_1112	COG1558	bacterial-type flagellum-dependent cell motility
BG04_1113	COG1815	bacterial-type flagellum-dependent cell motility
BG04_1114	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BG04_1115	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BG04_1117	COG4974	Belongs to the 'phage' integrase family
BG04_1118	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BG04_1119	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BG04_1120	COG0758	DNA mediated transformation
BG04_1121	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BG04_1122	COG0045	succinate-CoA ligase (ADP-forming) activity
BG04_1126	COG0335	large ribosomal subunit rRNA binding
BG04_1128	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BG04_113	COG2910	NAD(P)H-binding
BG04_1130	COG1837	Belongs to the UPF0109 family
BG04_1131	COG0228	four-way junction DNA binding
BG04_1132	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BG04_1134	COG0552	protein localization to endoplasmic reticulum
BG04_1135	COG1196	nuclear chromosome segregation
BG04_1137	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BG04_1138	COG1028	Short-chain dehydrogenase reductase Sdr
BG04_1139	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BG04_1140	COG0416	fatty acid biosynthetic process
BG04_1141	COG1349	DNA-binding transcription factor activity
BG04_1142	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BG04_1143	COG1760	l-serine dehydratase
BG04_1144	COG1760	l-serine dehydratase
BG04_1146	COG1461	Dihydroxyacetone kinase
BG04_1147	COG1302	Protein conserved in bacteria
BG04_1148	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BG04_1149	COG1564	THIamine pyrophosphokinase
BG04_1150	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BG04_1151	COG1162	GTPase activity
BG04_1152	COG2815	serine threonine protein kinase
BG04_1152	COG0515	serine threonine protein kinase
BG04_1153	COG0631	protein serine/threonine phosphatase activity
BG04_1155	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BG04_1155	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BG04_1156	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BG04_1158	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BG04_1159	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BG04_1160	COG1758	RNA polymerase activity
BG04_1161	COG0194	GDP metabolic process
BG04_1162	COG2052	Domain of unknown function (DUF370)
BG04_1165	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BG04_1167	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BG04_1170	COG0543	2 iron, 2 sulfur cluster binding
BG04_1173	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BG04_1176	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BG04_1177	COG0564	pseudouridine synthase activity
BG04_1178	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BG04_118	COG3546	catalase activity
BG04_1181	COG3599	regulation of cell shape
BG04_1182	COG2302	S4 RNA-binding domain
BG04_1183	COG0762	integral membrane protein
BG04_1184	COG1799	cell septum assembly
BG04_1185	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BG04_1187	COG1873	PFAM PRC-barrel domain
BG04_1188	COG1191	sigma factor activity
BG04_1189	COG1191	sigma factor activity
BG04_119	COG4607	ABC-type enterochelin transport system periplasmic component
BG04_1191	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BG04_1192	COG0849	cell division
BG04_1193	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BG04_1194	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BG04_1195	COG0772	Belongs to the SEDS family
BG04_1196	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BG04_1197	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BG04_1198	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BG04_1199	COG0768	penicillin binding
BG04_120	COG4604	ABC transporter, ATP-binding protein
BG04_1201	COG4839	cell division protein FtsL
BG04_1203	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BG04_1205	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BG04_1206	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BG04_1207	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BG04_1208	COG0439	Biotin carboxylase
BG04_1209	COG0454	-acetyltransferase
BG04_121	COG4605	iron ion homeostasis
BG04_1211	COG1024	Enoyl-CoA hydratase
BG04_1212	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BG04_1213	COG1399	metal-binding, possibly nucleic acid-binding protein
BG04_1214	COG1323	Belongs to the UPF0348 family
BG04_1215	COG3480	Lon protease (S16) C-terminal proteolytic domain
BG04_1216	COG1752	Esterase of the alpha-beta hydrolase superfamily
BG04_1217	COG3314	Sporulation integral membrane protein YlbJ
BG04_1218	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BG04_1219	COG0742	ribosomal rna small subunit methyltransferase
BG04_122	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BG04_1221	COG4471	UPF0298 protein
BG04_1223	COG3679	Belongs to the UPF0342 family
BG04_1227	COG4347	Protein of unknown function (DUF1405)
BG04_1229	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BG04_123	COG3773	Cell wall hydrolase
BG04_1232	COG5582	Belongs to the UPF0302 family
BG04_1233	COG0457	Tetratricopeptide repeat
BG04_1234	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BG04_1235	COG0287	Prephenate dehydrogenase
BG04_1236	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BG04_1237	COG0159	tryptophan synthase activity
BG04_1239	COG0135	phosphoribosylanthranilate isomerase activity
BG04_1240	COG0134	indole-3-glycerol-phosphate synthase activity
BG04_1241	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BG04_1243	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BG04_1244	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BG04_1245	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BG04_1246	COG0105	UTP biosynthetic process
BG04_1247	COG0142	geranyltranstransferase activity
BG04_1248	COG2226	methyltransferase
BG04_1249	COG0142	geranyltranstransferase activity
BG04_1251	COG0302	gtp cyclohydrolase
BG04_1252	COG0776	regulation of translation
BG04_1253	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BG04_1261	COG1304	FMN binding
BG04_1262	COG0539	negative regulation of cytoplasmic translation
BG04_1264	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BG04_1267	COG2959	enzyme of heme biosynthesis
BG04_1268	COG3773	Cell wall hydrolase
BG04_1268	COG3409	Peptidoglycan-binding domain 1 protein
BG04_1269	COG2339	peptidase activity
BG04_1270	COG0252	asparaginase activity
BG04_1271	COG0492	ferredoxin-NADP+ reductase activity
BG04_1272	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BG04_1273	COG4862	establishment of competence for transformation
BG04_1274	COG0789	Transcriptional regulator
BG04_1275	COG1408	metallophosphoesterase
BG04_1278	COG1266	CAAX protease self-immunity
BG04_1279	COG0514	ATP-dependent DNA helicase (RecQ)
BG04_128	COG1063	alcohol dehydrogenase
BG04_1281	COG1141	Ferredoxin
BG04_1282	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BG04_1283	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BG04_1284	COG0739	heme binding
BG04_1285	COG5002	protein histidine kinase activity
BG04_1286	COG0745	RESPONSE REGULATOR receiver
BG04_1287	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BG04_1288	COG1333	cytochrome c biogenesis protein
BG04_1289	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BG04_129	COG3775	system Galactitol-specific IIC component
BG04_1290	COG1187	pseudouridine synthase activity
BG04_1291	COG0700	Nucleoside recognition
BG04_1292	COG2715	membrane protein required for spore maturation
BG04_1293	COG1686	Belongs to the peptidase S11 family
BG04_1294	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BG04_1295	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BG04_1296	COG1547	Domain of unknown function (DUF309)
BG04_1298	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BG04_1299	COG4086	secreted protein
BG04_130	COG3414	Phosphotransferase system galactitol-specific IIB component
BG04_1301	COG0697	spore germination
BG04_1304	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BG04_131	COG3414	Phosphotransferase system galactitol-specific IIB component
BG04_1311	COG1686	Belongs to the peptidase S11 family
BG04_1314	COG4974	Belongs to the 'phage' integrase family
BG04_1316	COG0735	belongs to the Fur family
BG04_1317	COG1300	Membrane
BG04_1318	COG0494	nUDIX hydrolase
BG04_1320	COG0667	Aldo Keto reductase
BG04_1322	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BG04_1323	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BG04_1325	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BG04_1327	COG1073	alpha beta
BG04_1329	COG0300	oxidoreductase activity
BG04_1330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BG04_1331	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BG04_1332	COG1902	pentaerythritol trinitrate reductase activity
BG04_1334	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BG04_1335	COG1012	belongs to the aldehyde dehydrogenase family
BG04_1336	COG2508	Transcriptional regulator
BG04_134	COG2249	NAD(P)H dehydrogenase (quinone) activity
BG04_1340	COG0167	dihydroorotate dehydrogenase activity
BG04_1340	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BG04_1341	COG0493	'glutamate synthase
BG04_1342	COG2195	Cleaves the N-terminal amino acid of tripeptides
BG04_1343	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BG04_1346	COG1376	ErfK ybiS ycfS ynhG family protein
BG04_1347	COG4129	membrane
BG04_1348	COG1126	abc transporter atp-binding protein
BG04_1349	COG0765	amino acid transport
BG04_135	COG0681	Belongs to the peptidase S26 family
BG04_1350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BG04_1352	COG1703	isobutyryl-CoA mutase activity
BG04_1353	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BG04_1353	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BG04_1355	COG0508	dehydrogenase complex catalyzes the overall conversion of
BG04_1356	COG0022	dehydrogenase e1 component
BG04_1357	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BG04_1358	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BG04_1361	COG0280	phosphate acetyltransferase
BG04_1362	COG3829	transcription factor binding
BG04_1362	COG3290	protein histidine kinase activity
BG04_1364	COG0584	glycerophosphoryl diester phosphodiesterase
BG04_1365	COG3093	addiction module antidote protein HigA
BG04_1366	COG3104	oligopeptide transport
BG04_1367	COG0745	RESPONSE REGULATOR receiver
BG04_1368	COG0750	zinc metalloprotease
BG04_1369	COG0497	DNA recombination
BG04_1371	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BG04_1374	COG1722	exodeoxyribonuclease VII activity
BG04_1376	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BG04_1377	COG1302	Protein conserved in bacteria
BG04_1378	COG0439	Biotin carboxylase
BG04_1379	COG0511	ligase activity, forming carbon-carbon bonds
BG04_1387	COG3854	ATPases associated with a variety of cellular activities
BG04_1389	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BG04_139	COG1193	negative regulation of DNA recombination
BG04_1390	COG0006	proline dipeptidase activity
BG04_1391	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BG04_1393	COG3872	metal-dependent enzyme
BG04_1395	COG1752	Esterase of the alpha-beta hydrolase superfamily
BG04_1396	COG1321	iron dependent repressor
BG04_1397	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BG04_1399	COG0095	Lipoate-protein ligase
BG04_1400	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BG04_1402	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BG04_1403	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BG04_1404	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BG04_141	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BG04_1410	COG4970	Tfp pilus assembly protein FimT
BG04_1411	COG4537	Required for transformation and DNA binding
BG04_1412	COG1459	type II secretion system
BG04_1413	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BG04_142	COG1396	sequence-specific DNA binding
BG04_143	COG0861	Integral membrane protein TerC family
BG04_1435	COG1196	nuclear chromosome segregation
BG04_1435	COG0741	lytic transglycosylase activity
BG04_1435	COG0739	heme binding
BG04_1449	COG2369	cell adhesion
BG04_145	COG1609	Transcriptional regulator
BG04_1452	COG5484	DNA packaging
BG04_1452	COG3728	DNA packaging
BG04_146	COG1959	2 iron, 2 sulfur cluster binding
BG04_1463	COG3645	SOS response
BG04_1463	COG3646	Phage regulatory protein
BG04_1468	COG1484	DNA-dependent DNA replication
BG04_1469	COG3935	DnaD domain protein
BG04_1482	COG1396	sequence-specific DNA binding
BG04_1483	COG2856	Zn peptidase
BG04_1486	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BG04_1487	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BG04_1488	COG1393	Belongs to the ArsC family
BG04_1490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BG04_1493	COG1940	carbohydrate kinase activity
BG04_1494	COG4483	Protein conserved in bacteria
BG04_1495	COG0457	Tetratricopeptide repeat
BG04_1495	COG0705	Rhomboid family
BG04_1498	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BG04_15	COG0640	Transcriptional regulator
BG04_1500	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BG04_1503	COG0704	Plays a role in the regulation of phosphate uptake
BG04_1506	COG0477	Major facilitator Superfamily
BG04_1513	COG2839	Protein conserved in bacteria
BG04_1516	COG2814	Major facilitator Superfamily
BG04_1517	COG1388	LysM domain
BG04_1518	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BG04_1519	COG4709	membrane
BG04_1520	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BG04_1521	COG0735	belongs to the Fur family
BG04_1522	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BG04_1523	COG1121	(ABC) transporter
BG04_1525	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BG04_1526	COG0513	Belongs to the DEAD box helicase family
BG04_1528	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BG04_1529	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BG04_1530	COG2384	SAM-dependent methyltransferase
BG04_1531	COG2010	Cytochrome c
BG04_1532	COG1960	acyl-CoA dehydrogenase activity
BG04_1533	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BG04_1534	COG0358	DNA primase activity
BG04_1535	COG1671	Belongs to the UPF0178 family
BG04_1536	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BG04_1537	COG0517	IMP dehydrogenase activity
BG04_1540	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BG04_1541	COG0295	cytidine deaminase activity
BG04_1542	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BG04_1544	COG1480	7TM receptor with intracellular HD hydrolase
BG04_1545	COG1702	phosphate starvation-inducible protein PhoH
BG04_1550	COG1030	water channel activity
BG04_1551	COG1610	YqeY-like protein
BG04_1552	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BG04_1553	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BG04_1554	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BG04_1555	COG2264	protein methyltransferase activity
BG04_1558	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BG04_1559	COG1420	regulation of RNA biosynthetic process
BG04_1560	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BG04_1561	COG0481	GTPase activity
BG04_1563	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BG04_1564	COG0268	Binds directly to 16S ribosomal RNA
BG04_1565	COG1466	dna polymerase III delta subunit
BG04_1567	COG0658	competence protein
BG04_1567	COG2333	competence protein COMEC
BG04_1568	COG2131	deaminase
BG04_1569	COG1555	photosystem II stabilization
BG04_1569	COG1596	polysaccharide export
BG04_1570	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BG04_1571	COG2226	methyltransferase
BG04_1572	COG0799	negative regulation of ribosome biogenesis
BG04_1573	COG1713	HD superfamily hydrolase involved in NAD metabolism
BG04_1574	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BG04_1575	COG1534	Rna-binding protein
BG04_1576	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BG04_1577	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BG04_1578	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BG04_1580	COG0688	phosphatidylethanolamine metabolic process
BG04_1581	COG1183	phosphatidylcholine synthase activity
BG04_1583	COG1191	sigma factor activity
BG04_1586	COG0626	cystathionine gamma-synthase activity
BG04_1587	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BG04_1588	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BG04_1589	COG2226	methyltransferase
BG04_1592	COG0768	penicillin binding
BG04_1593	COG1335	isochorismatase
BG04_1594	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BG04_1595	COG0572	uridine kinase
BG04_1599	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BG04_160	COG3773	Cell wall hydrolase
BG04_1600	COG3906	Belongs to the UPF0473 family
BG04_1602	COG4472	Bacterial protein of unknown function (DUF965)
BG04_1604	COG0628	permease
BG04_1607	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BG04_1609	COG0482	sulfurtransferase activity
BG04_161	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BG04_1610	COG1104	cysteine desulfurase activity
BG04_1611	COG1959	2 iron, 2 sulfur cluster binding
BG04_1612	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BG04_1613	COG0581	inorganic phosphate transmembrane transporter activity
BG04_1614	COG0573	inorganic phosphate transmembrane transporter activity
BG04_1615	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BG04_1616	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BG04_1618	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BG04_1619	COG0124	histidyl-tRNA synthetase
BG04_1621	COG1490	D-aminoacyl-tRNA deacylase activity
BG04_1622	COG0860	N-Acetylmuramoyl-L-alanine amidase
BG04_1623	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BG04_1624	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BG04_1625	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BG04_1625	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BG04_1626	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BG04_1626	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BG04_1628	COG2244	polysaccharide biosynthetic process
BG04_1629	COG2323	membrane
BG04_1631	COG1862	Preprotein translocase
BG04_1633	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BG04_1635	COG2255	four-way junction helicase activity
BG04_1641	COG1388	LysM domain
BG04_1642	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BG04_1643	COG0157	Belongs to the NadC ModD family
BG04_1644	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BG04_1645	COG1104	cysteine desulfurase activity
BG04_1646	COG1827	regulation of RNA biosynthetic process
BG04_1647	COG0077	Prephenate dehydratase
BG04_1648	COG4492	Belongs to the UPF0735 family
BG04_1649	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BG04_1650	COG3290	protein histidine kinase activity
BG04_1652	COG2868	ribosomal protein
BG04_1654	COG1530	ribonuclease E activity
BG04_1655	COG1994	Peptidase M50
BG04_1656	COG0739	heme binding
BG04_1657	COG2894	cell division
BG04_1658	COG0850	regulation of cytokinetic process
BG04_1659	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BG04_166	COG3546	catalase activity
BG04_1660	COG1792	Involved in formation and maintenance of cell shape
BG04_1661	COG1077	Cell shape determining protein MreB Mrl
BG04_1662	COG2003	Belongs to the UPF0758 family
BG04_1663	COG0424	maF-like protein
BG04_1665	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BG04_1667	COG2322	membrane
BG04_1668	COG0285	dihydrofolate synthase activity
BG04_1669	COG0525	valine-tRNA ligase activity
BG04_1670	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BG04_1671	COG1388	LysM domain
BG04_1672	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BG04_1673	COG0113	porphobilinogen synthase activity
BG04_1674	COG1587	Uroporphyrinogen-III synthase
BG04_1675	COG0181	hydroxymethylbilane synthase activity
BG04_1676	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BG04_1679	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BG04_1680	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BG04_1681	COG1067	ATP-dependent peptidase activity
BG04_1681	COG0470	DNA polymerase III
BG04_1682	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BG04_1683	COG0544	peptidyl-prolyl cis-trans isomerase activity
BG04_1684	COG1477	protein flavinylation
BG04_1684	COG0457	Tetratricopeptide repeat
BG04_1685	COG0066	3-isopropylmalate dehydratase activity
BG04_1686	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BG04_1688	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BG04_1689	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BG04_1690	COG0440	acetolactate synthase activity
BG04_1691	COG0028	Belongs to the TPP enzyme family
BG04_1693	COG0622	Phosphoesterase
BG04_1696	COG5401	PFAM Sporulation and spore germination
BG04_1697	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BG04_1698	COG1846	Transcriptional regulator
BG04_170	COG1280	lysine exporter protein (LysE YggA)
BG04_1700	COG0306	phosphate transporter
BG04_1701	COG1392	Phosphate transport regulator
BG04_1702	COG0768	penicillin binding
BG04_1704	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BG04_1705	COG0431	NADPH-dependent FMN reductase
BG04_1706	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BG04_1707	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BG04_1708	COG1116	anion transmembrane transporter activity
BG04_1709	COG0475	glutathione-regulated potassium exporter activity
BG04_171	COG1917	Cupin 2, conserved barrel domain protein
BG04_171	COG2207	Transcriptional regulator
BG04_1710	COG0490	domain, Protein
BG04_1712	COG2197	response regulator
BG04_1713	COG0824	Thioesterase
BG04_1714	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BG04_1715	COG1053	succinate dehydrogenase
BG04_1716	COG2009	succinate dehydrogenase
BG04_1717	COG1719	4-vinyl reductase, 4VR
BG04_1718	COG0527	aspartate kinase activity
BG04_172	COG4585	Histidine kinase
BG04_172	COG2203	Gaf domain
BG04_1720	COG3118	belongs to the thioredoxin family
BG04_1721	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BG04_1722	COG2086	electron transfer activity
BG04_1723	COG1024	Enoyl-CoA hydratase
BG04_1724	COG1309	transcriptional regulator
BG04_1725	COG0318	PFAM AMP-dependent synthetase and ligase
BG04_1726	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BG04_1727	COG3766	membrane
BG04_1728	COG1193	negative regulation of DNA recombination
BG04_1729	COG1796	DNA polymerase
BG04_1729	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BG04_1730	COG1286	toxin biosynthetic process
BG04_1731	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BG04_1732	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BG04_1733	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BG04_1733	COG0072	phenylalanine-tRNA ligase activity
BG04_1734	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BG04_1735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BG04_1737	COG1363	Peptidase, m42
BG04_174	COG0584	glycerophosphoryl diester phosphodiesterase
BG04_1741	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BG04_1742	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BG04_1743	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BG04_1744	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BG04_1746	COG1484	DNA-dependent DNA replication
BG04_1747	COG3611	Membrane attachment protein
BG04_1748	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BG04_1750	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BG04_1751	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BG04_1753	COG1971	Probably functions as a manganese efflux pump
BG04_1754	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BG04_1755	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BG04_1755	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BG04_1756	COG5002	protein histidine kinase activity
BG04_1757	COG0745	RESPONSE REGULATOR receiver
BG04_1759	COG0039	L-malate dehydrogenase activity
BG04_1760	COG0538	isocitrate dehydrogenase activity
BG04_1761	COG0372	Belongs to the citrate synthase family
BG04_1762	COG2707	UPF0756 membrane protein
BG04_1763	COG0628	permease
BG04_1764	COG3030	protein affecting phage T7 exclusion by the F plasmid
BG04_1766	COG0825	malonyl-CoA metabolic process
BG04_1767	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BG04_1768	COG2186	Transcriptional regulator
BG04_1769	COG0281	malic enzyme
BG04_1770	COG0587	DNA-directed DNA polymerase activity
BG04_1773	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BG04_1775	COG4109	DRTGG domain
BG04_1777	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BG04_1780	COG0165	Argininosuccinate lyase
BG04_1781	COG0137	argininosuccinate synthase activity
BG04_1784	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BG04_1785	COG0827	DNA restriction-modification system
BG04_1786	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BG04_1787	COG3874	Sporulation protein YtfJ
BG04_1789	COG1714	RDD family
BG04_179	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BG04_1790	COG0616	signal peptide processing
BG04_1791	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BG04_1792	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BG04_1794	COG0301	tRNA thio-modification
BG04_1795	COG1104	cysteine desulfurase activity
BG04_1796	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BG04_1797	COG1309	transcriptional regulator
BG04_1798	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BG04_1799	COG1956	GAF domain-containing protein
BG04_1801	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BG04_1802	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BG04_1803	COG0454	-acetyltransferase
BG04_1804	COG0517	IMP dehydrogenase activity
BG04_1805	COG0123	including yeast histone deacetylase and acetoin utilization protein
BG04_1809	COG1605	Chorismate mutase
BG04_1809	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BG04_181	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BG04_1810	COG3118	belongs to the thioredoxin family
BG04_1811	COG4980	gas vesicle protein
BG04_1814	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BG04_1816	COG1674	ftsk spoiiie
BG04_1817	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BG04_1818	COG4848	Belongs to the UPF0354 family
BG04_1819	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BG04_1820	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BG04_1821	COG1363	Peptidase, m42
BG04_1822	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BG04_1823	COG5584	Small secreted protein
BG04_1824	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BG04_1826	COG0510	thiamine kinase activity
BG04_1827	COG1523	belongs to the glycosyl hydrolase 13 family
BG04_1829	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BG04_1830	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BG04_1831	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BG04_1832	COG1349	DNA-binding transcription factor activity
BG04_1833	COG1187	pseudouridine synthase activity
BG04_1834	COG2244	polysaccharide biosynthetic process
BG04_1835	COG2081	HI0933 family
BG04_1837	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BG04_1838	COG0495	leucyl-tRNA aminoacylation
BG04_184	COG0346	lactoylglutathione lyase activity
BG04_1840	COG2610	gluconate transmembrane transporter activity
BG04_1841	COG2814	Major facilitator Superfamily
BG04_1844	COG1242	4 iron, 4 sulfur cluster binding
BG04_1845	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BG04_1847	COG2267	carboxylic ester hydrolase activity
BG04_1849	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BG04_1850	COG0671	phosphoesterase, PA-phosphatase related
BG04_1851	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BG04_1851	COG0438	transferase activity, transferring glycosyl groups
BG04_1852	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BG04_1853	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BG04_1855	COG1506	peptidase
BG04_1856	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BG04_1857	COG1116	anion transmembrane transporter activity
BG04_1858	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BG04_1859	COG0494	nUDIX hydrolase
BG04_1861	COG4824	toxin secretion phage lysis holin
BG04_1862	COG0783	Belongs to the Dps family
BG04_1864	COG0288	reversible hydration of carbon dioxide
BG04_1865	COG0523	cobalamin synthesis protein
BG04_1867	COG0254	rRNA binding
BG04_1868	COG1271	oxidase subunit
BG04_1869	COG1294	oxidase, subunit
BG04_187	COG1136	(ABC) transporter
BG04_1870	COG0716	FMN binding
BG04_1874	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BG04_1875	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BG04_1876	COG4948	Mandelate Racemase Muconate Lactonizing
BG04_1877	COG0318	PFAM AMP-dependent synthetase and ligase
BG04_1878	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BG04_1879	COG0596	Alpha beta hydrolase
BG04_188	COG0577	efflux transmembrane transporter activity
BG04_1880	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BG04_1881	COG1169	isochorismate synthase
BG04_1882	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BG04_1884	COG0058	SHG alpha-glucan phosphorylase activity
BG04_1885	COG0297	glycogen (starch) synthase activity
BG04_1886	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BG04_189	COG5002	protein histidine kinase activity
BG04_189	COG3850	Histidine kinase
BG04_19	COG0531	amino acid
BG04_1912	COG0318	PFAM AMP-dependent synthetase and ligase
BG04_1913	COG1285	pathogenesis
BG04_1917	COG0529	Catalyzes the synthesis of activated sulfate
BG04_1919	COG0306	phosphate transporter
BG04_1921	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BG04_1922	COG0346	lactoylglutathione lyase activity
BG04_1923	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BG04_1925	COG0166	Belongs to the GPI family
BG04_1927	COG2111	Na H antiporter
BG04_1927	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BG04_1928	COG2111	Na H antiporter
BG04_1929	COG1006	Multisubunit Na H antiporter MnhC subunit
BG04_1930	COG0651	ATP synthesis coupled electron transport
BG04_1931	COG1863	multisubunit Na H antiporter MnhE subunit
BG04_1932	COG2212	antiporter activity
BG04_1933	COG1320	monovalent cation:proton antiporter activity
BG04_1934	COG1979	alcohol dehydrogenase
BG04_1935	COG2155	Conserved Protein
BG04_1936	COG1098	S1 RNA binding domain
BG04_1937	COG0436	Aminotransferase
BG04_1938	COG1522	sequence-specific DNA binding
BG04_1939	COG2267	carboxylic ester hydrolase activity
BG04_194	COG5002	protein histidine kinase activity
BG04_1940	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BG04_1941	COG2032	superoxide dismutase activity
BG04_1944	COG5018	Exonuclease
BG04_1945	COG2050	protein possibly involved in aromatic compounds catabolism
BG04_1947	COG1418	mRNA catabolic process
BG04_1949	COG2056	Na+-H+ antiporter family
BG04_195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BG04_1950	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BG04_1951	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BG04_1952	COG3584	3D domain protein
BG04_1954	COG1252	NADH dehydrogenase
BG04_1955	COG0492	ferredoxin-NADP+ reductase activity
BG04_1957	COG0316	Belongs to the HesB IscA family
BG04_1958	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BG04_1959	COG4844	belongs to the
BG04_196	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BG04_1960	COG1252	NADH dehydrogenase
BG04_1961	COG4837	Protein of unknown function (DUF1462)
BG04_1962	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BG04_1963	COG0083	homoserine kinase activity
BG04_1964	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BG04_1965	COG0460	homoserine dehydrogenase
BG04_1966	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BG04_1967	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BG04_1968	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BG04_1969	COG0647	UMP catabolic process
BG04_1970	COG2445	Protein of unknown function DUF86
BG04_1972	COG4470	Protein conserved in bacteria
BG04_1974	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BG04_1975	COG0739	heme binding
BG04_1977	COG0733	neurotransmitter:sodium symporter activity
BG04_1979	COG3377	Domain of unknown function (DUF1805)
BG04_1980	COG1801	Protein of unknown function DUF72
BG04_1981	COG0719	Fe-S assembly protein
BG04_1982	COG0822	iron-sulfur transferase activity
BG04_1983	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BG04_1984	COG0719	Fe-S assembly protein
BG04_1985	COG0396	ATPase activity
BG04_1986	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BG04_1987	COG1464	Belongs to the NlpA lipoprotein family
BG04_1988	COG2011	ABC-type metal ion transport system permease component
BG04_1989	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BG04_1990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BG04_1991	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BG04_1993	COG0509	glycine decarboxylation via glycine cleavage system
BG04_1994	COG1393	Belongs to the ArsC family
BG04_1995	COG1960	acyl-CoA dehydrogenase activity
BG04_1996	COG0183	Belongs to the thiolase family
BG04_1997	COG1024	Enoyl-CoA hydratase
BG04_1997	COG1250	3-hydroxyacyl-CoA dehydrogenase
BG04_20	COG1959	2 iron, 2 sulfur cluster binding
BG04_2002	COG1120	ATPase activity
BG04_2003	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BG04_2004	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BG04_2005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BG04_2008	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BG04_2009	COG1309	transcriptional regulator
BG04_2011	COG1028	Short-chain dehydrogenase reductase Sdr
BG04_2012	COG0477	Major facilitator Superfamily
BG04_2013	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BG04_2014	COG0583	DNA-binding transcription factor activity
BG04_2016	COG3850	Histidine kinase
BG04_2016	COG5002	protein histidine kinase activity
BG04_2017	COG0745	RESPONSE REGULATOR receiver
BG04_2018	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BG04_2019	COG0671	phosphoesterase, PA-phosphatase related
BG04_202	COG4989	oxidoreductase activity
BG04_2020	COG1846	Transcriptional regulator
BG04_2021	COG0778	Nitroreductase
BG04_2022	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BG04_2023	COG0314	molybdopterin synthase activity
BG04_2024	COG1763	Mo-molybdopterin cofactor biosynthetic process
BG04_2025	COG0303	'Molybdopterin
BG04_2026	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BG04_2027	COG0746	molybdenum cofactor guanylyltransferase activity
BG04_2029	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BG04_2030	COG5609	conserved protein (DUF2294)
BG04_2031	COG3383	formate dehydrogenase (NAD+) activity
BG04_2032	COG2427	Protein of unknown function (DUF1641)
BG04_2033	COG0725	ABC transporter, periplasmic molybdate-binding protein
BG04_2034	COG4149	molybdate abc transporter
BG04_2035	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BG04_2036	COG0557	exoribonuclease II activity
BG04_2037	COG1647	Serine aminopeptidase, S33
BG04_2038	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BG04_204	COG0697	spore germination
BG04_2046	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BG04_205	COG1917	Cupin 2, conserved barrel domain protein
BG04_205	COG2207	Transcriptional regulator
BG04_2050	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BG04_2052	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BG04_2053	COG1660	Displays ATPase and GTPase activities
BG04_2054	COG1051	belongs to the nudix hydrolase family
BG04_2055	COG0492	ferredoxin-NADP+ reductase activity
BG04_2056	COG0457	Tetratricopeptide repeat
BG04_2057	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BG04_2057	COG0140	phosphoribosyl-ATP diphosphatase activity
BG04_2058	COG0107	imidazoleglycerol-phosphate synthase activity
BG04_2059	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BG04_2060	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BG04_2061	COG0131	Imidazoleglycerol-phosphate dehydratase
BG04_2062	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BG04_2063	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BG04_2064	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BG04_2065	COG0110	maltose O-acetyltransferase activity
BG04_2066	COG0546	phosphoglycolate phosphatase activity
BG04_2067	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BG04_2068	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BG04_2069	COG1950	PFAM Membrane protein of
BG04_2070	COG1983	PspC domain protein
BG04_2071	COG3595	metallopeptidase activity
BG04_2073	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BG04_2074	COG0556	nucleotide-excision repair
BG04_2075	COG2204	response regulator
BG04_2076	COG1012	belongs to the aldehyde dehydrogenase family
BG04_2077	COG0506	proline dehydrogenase activity
BG04_2079	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BG04_2080	COG3409	Peptidoglycan-binding domain 1 protein
BG04_2080	COG0793	Belongs to the peptidase S41A family
BG04_2081	COG0739	heme binding
BG04_2082	COG2177	Part of the ABC transporter FtsEX involved in
BG04_2083	COG2884	Cell division ATP-binding protein ftsE
BG04_2084	COG0655	NAD(P)H dehydrogenase (quinone) activity
BG04_2086	COG0805	protein transport
BG04_2087	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BG04_2088	COG3540	Alkaline phosphatase
BG04_2089	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BG04_2090	COG0653	protein targeting
BG04_2091	COG0456	acetyltransferase
BG04_2092	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BG04_2094	COG1516	flagellar protein fliS
BG04_2095	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BG04_2097	COG1113	amino acid transport
BG04_2100	COG1454	alcohol dehydrogenase
BG04_2101	COG1510	regulation of RNA biosynthetic process
BG04_2102	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BG04_2103	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BG04_2104	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BG04_2105	COG1256	bacterial-type flagellum assembly
BG04_2105	COG4786	Flagellar basal body rod
BG04_2109	COG1040	competence protein
BG04_2110	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BG04_2111	COG1307	EDD domain protein, DegV family
BG04_2112	COG1728	Protein conserved in bacteria
BG04_2114	COG2197	response regulator
BG04_2115	COG4585	Histidine kinase
BG04_2116	COG1739	Uncharacterized protein family UPF0029
BG04_2117	COG1316	TRANSCRIPTIONal
BG04_2118	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BG04_2119	COG1585	Membrane protein implicated in regulation of membrane protease activity
BG04_2120	COG2268	Band 7 protein
BG04_2121	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BG04_2123	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BG04_2125	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BG04_2126	COG0791	NLP P60 protein
BG04_2126	COG1388	LysM domain
BG04_2127	COG0629	single-stranded DNA binding
BG04_2132	COG4786	Flagellar basal body rod
BG04_2133	COG4786	Flagellar basal body rod
BG04_2134	COG1077	Cell shape determining protein MreB Mrl
BG04_2135	COG1609	Transcriptional regulator
BG04_2136	COG0739	heme binding
BG04_2137	COG2385	sporulation resulting in formation of a cellular spore
BG04_2140	COG4836	Membrane
BG04_2141	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BG04_2142	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BG04_2143	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BG04_2144	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BG04_2145	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BG04_2146	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BG04_2147	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BG04_2148	COG0356	it plays a direct role in the translocation of protons across the membrane
BG04_2151	COG1404	Belongs to the peptidase S8 family
BG04_2152	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BG04_2153	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BG04_2156	COG0698	ribose 5-phosphate isomerase
BG04_2158	COG1971	Probably functions as a manganese efflux pump
BG04_2159	COG0009	L-threonylcarbamoyladenylate synthase
BG04_2163	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BG04_2166	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BG04_2168	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BG04_2169	COG0191	fructose-bisphosphate aldolase activity
BG04_2170	COG2204	response regulator
BG04_2171	COG4821	SIS domain
BG04_2172	COG0504	CTP synthase activity
BG04_2174	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BG04_2174	COG1703	isobutyryl-CoA mutase activity
BG04_2174	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BG04_2176	COG1960	acyl-CoA dehydrogenase activity
BG04_2177	COG1960	acyl-CoA dehydrogenase activity
BG04_2178	COG1250	3-hydroxyacyl-CoA dehydrogenase
BG04_2179	COG0183	Belongs to the thiolase family
BG04_2180	COG0247	lactate metabolic process
BG04_2180	COG2181	nitrate reductase activity
BG04_2181	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BG04_2183	COG0018	arginyl-trna synthetase
BG04_2184	COG4506	Protein conserved in bacteria
BG04_2185	COG0010	Belongs to the arginase family
BG04_2186	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BG04_2187	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BG04_2189	COG1994	Peptidase M50
BG04_2190	COG1942	4-Oxalocrotonate Tautomerase
BG04_2191	COG3465	dGTPase activity
BG04_2192	COG1078	dGTPase activity
BG04_2193	COG4844	belongs to the
BG04_2195	COG0095	Lipoate-protein ligase
BG04_2196	COG0280	phosphate acetyltransferase
BG04_2198	COG3773	Cell wall hydrolase
BG04_220	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BG04_2200	COG2363	Small membrane protein
BG04_2202	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BG04_2204	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BG04_2205	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BG04_2206	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BG04_2206	COG2508	Transcriptional regulator
BG04_2207	COG0686	Belongs to the AlaDH PNT family
BG04_2209	COG0351	phosphomethylpyrimidine kinase
BG04_2210	COG0561	phosphatase activity
BG04_2211	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BG04_2212	COG2190	(PTS) system
BG04_2212	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BG04_2212	COG1263	PTS System
BG04_2214	COG0463	Glycosyl transferase, family 2
BG04_2216	COG2076	Multidrug Resistance protein
BG04_2217	COG0438	transferase activity, transferring glycosyl groups
BG04_2219	COG0728	peptidoglycan biosynthetic process
BG04_222	COG0583	DNA-binding transcription factor activity
BG04_2222	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BG04_2223	COG4988	ABC transporter
BG04_2224	COG1294	oxidase, subunit
BG04_2225	COG1271	oxidase subunit
BG04_2226	COG3610	response to peptide
BG04_2227	COG2966	Psort location CytoplasmicMembrane, score
BG04_2228	COG1609	Transcriptional regulator
BG04_2230	COG2814	Major facilitator Superfamily
BG04_2233	COG1966	Carbon starvation protein
BG04_2234	COG0753	catalase activity
BG04_2235	COG5002	protein histidine kinase activity
BG04_2238	COG0471	metal ion transport
BG04_2239	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BG04_224	COG1301	dicarboxylic acid transport
BG04_2241	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BG04_2242	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BG04_2244	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BG04_2245	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BG04_2246	COG4853	Protein conserved in bacteria
BG04_2248	COG5002	protein histidine kinase activity
BG04_2249	COG0745	RESPONSE REGULATOR receiver
BG04_225	COG2824	Alkylphosphonate utilization operon protein PhnA
BG04_2254	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BG04_2255	COG0305	Participates in initiation and elongation during chromosome replication
BG04_2257	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BG04_2259	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BG04_2262	COG0012	GTP binding
BG04_2263	COG4481	Protein conserved in bacteria
BG04_2264	COG0668	transmembrane transport
BG04_2265	COG3949	Membrane
BG04_2267	COG1475	DNA binding
BG04_2268	COG1192	Involved in chromosome partitioning
BG04_2269	COG1475	DNA binding
BG04_2271	COG0445	tRNA wobble uridine modification
BG04_2272	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BG04_2273	COG1847	R3H domain protein
BG04_2274	COG0706	membrane insertase activity
BG04_2275	COG0594	ribonuclease P activity
BG04_2276	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BG04_2277	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BG04_2278	COG0592	DNA-directed DNA polymerase activity
BG04_2279	COG2501	S4 domain
BG04_2280	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BG04_2281	COG0187	DNA topoisomerase II activity
BG04_2282	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BG04_2289	COG0516	GMP reductase activity
BG04_2289	COG0517	IMP dehydrogenase activity
BG04_2292	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BG04_2295	COG1428	Deoxynucleoside kinase
BG04_2296	COG1428	Deoxynucleoside kinase
BG04_2297	COG1388	LysM domain
BG04_2297	COG3858	chitin binding
BG04_2298	COG1335	isochorismatase
BG04_2299	COG0590	tRNA wobble adenosine to inosine editing
BG04_230	COG0405	Gamma-glutamyltransferase
BG04_2300	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BG04_2301	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BG04_2302	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BG04_231	COG1073	alpha beta
BG04_2323	COG1982	Orn Lys Arg decarboxylase major
BG04_2324	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BG04_2325	COG3870	Protein conserved in bacteria
BG04_2326	COG0470	DNA polymerase III
BG04_2327	COG1774	PSP1 C-terminal conserved region
BG04_2328	COG4467	Involved in initiation control of chromosome replication
BG04_2329	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BG04_2330	COG2827	Endonuclease containing a URI domain
BG04_2331	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BG04_2332	COG2002	toxin-antitoxin pair type II binding
BG04_2334	COG0084	hydrolase, TatD family'
BG04_2336	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BG04_2338	COG4466	Protein conserved in bacteria
BG04_234	COG0477	Major facilitator Superfamily
BG04_2341	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BG04_2342	COG0251	oxidation-reduction process
BG04_2343	COG2088	sporulation resulting in formation of a cellular spore
BG04_2344	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BG04_2345	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BG04_2346	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BG04_2347	COG0193	aminoacyl-tRNA hydrolase activity
BG04_2349	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BG04_235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BG04_2350	COG2002	toxin-antitoxin pair type II binding
BG04_2351	COG2244	polysaccharide biosynthetic process
BG04_2352	COG3956	TIGRFAM MazG family protein
BG04_2353	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BG04_2356	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BG04_2357	COG1098	S1 RNA binding domain
BG04_2361	COG2304	oxidoreductase activity
BG04_2362	COG0515	serine threonine protein kinase
BG04_2363	COG0037	tRNA processing
BG04_2365	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BG04_2366	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BG04_2367	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BG04_2368	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BG04_2369	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BG04_2370	COG0512	Glutamine amidotransferase of anthranilate synthase
BG04_2371	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BG04_2372	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BG04_2373	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BG04_2374	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BG04_2379	COG3880	PFAM UvrB UvrC protein
BG04_238	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BG04_2380	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BG04_2381	COG0542	response to heat
BG04_2382	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BG04_2383	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BG04_2384	COG4956	integral membrane protein (PIN domain superfamily)
BG04_2385	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BG04_2387	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BG04_2388	COG1045	serine acetyltransferase
BG04_2389	COG0215	cysteine-tRNA ligase activity
BG04_2391	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BG04_2392	COG3688	RNA-binding protein containing a PIN domain
BG04_2394	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BG04_2395	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BG04_2396	COG0250	Participates in transcription elongation, termination and antitermination
BG04_2398	COG0081	regulation of translation
BG04_2399	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BG04_24	COG0281	malic enzyme
BG04_240	COG1960	acyl-CoA dehydrogenase activity
BG04_2401	COG2813	Specifically methylates the guanine in position
BG04_2402	COG0085	RNA polymerase activity
BG04_2403	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BG04_2404	COG1358	cellular component organization or biogenesis
BG04_2405	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BG04_2406	COG0049	tRNA binding
BG04_2408	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BG04_2409	COG0051	transcription antitermination factor activity, RNA binding
BG04_241	COG1063	alcohol dehydrogenase
BG04_2410	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BG04_2411	COG0088	Forms part of the polypeptide exit tunnel
BG04_2412	COG0089	rRNA binding
BG04_2413	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BG04_2414	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BG04_2415	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BG04_2416	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BG04_2417	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BG04_2418	COG0255	Belongs to the universal ribosomal protein uL29 family
BG04_2419	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BG04_242	COG0745	RESPONSE REGULATOR receiver
BG04_2420	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BG04_2423	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BG04_2424	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BG04_2427	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BG04_2428	COG1841	ribosomal large subunit assembly
BG04_243	COG2205	protein histidine kinase activity
BG04_2430	COG0201	protein transport
BG04_2431	COG0563	adenylate kinase activity
BG04_2432	COG0024	Methionine aminopeptidase
BG04_2433	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BG04_2434	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BG04_2436	COG0202	RNA polymerase activity
BG04_2437	COG0203	ribosomal protein L17
BG04_2438	COG1122	ATPase activity
BG04_2439	COG1122	ATPase activity
BG04_244	COG1136	(ABC) transporter
BG04_2440	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BG04_2441	COG0101	tRNA pseudouridine synthase activity
BG04_2442	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BG04_2445	COG0860	N-Acetylmuramoyl-L-alanine amidase
BG04_2446	COG0489	protein tyrosine kinase activity
BG04_2447	COG0583	DNA-binding transcription factor activity
BG04_2449	COG2194	sulfuric ester hydrolase activity
BG04_245	COG0577	efflux transmembrane transporter activity
BG04_2450	COG0726	polysaccharide deacetylase
BG04_2466	COG1595	DNA-templated transcription, initiation
BG04_2467	COG5662	AntiSigma factor
BG04_2468	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BG04_2470	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BG04_2471	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BG04_2474	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BG04_2474	COG2213	PTS system mannitol-specific
BG04_2475	COG3711	transcriptional antiterminator
BG04_2476	COG0246	Mannitol dehydrogenase
BG04_2478	COG1376	ErfK ybiS ycfS ynhG family protein
BG04_2479	COG1970	mechanosensitive ion channel activity
BG04_248	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BG04_2480	COG1368	sulfuric ester hydrolase activity
BG04_2483	COG1176	ABC-type spermidine putrescine transport system, permease component I
BG04_2484	COG1177	transmembrane transport
BG04_2485	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BG04_2487	COG0745	RESPONSE REGULATOR receiver
BG04_2488	COG5002	protein histidine kinase activity
BG04_2491	COG3976	FMN-binding domain protein
BG04_2491	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BG04_2492	COG1181	Belongs to the D-alanine--D-alanine ligase family
BG04_2493	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BG04_2494	COG0513	Belongs to the DEAD box helicase family
BG04_2495	COG4294	response to UV
BG04_2496	COG0705	Rhomboid family
BG04_2497	COG0736	holo-[acyl-carrier-protein] synthase activity
BG04_2498	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BG04_2499	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BG04_25	COG2746	aminoglycoside 3-N-acetyltransferase activity
BG04_250	COG0730	response to heat
BG04_2500	COG0864	Transcriptional regulator
BG04_2501	COG2337	Toxic component of a toxin-antitoxin (TA) module
BG04_2502	COG1366	Belongs to the anti-sigma-factor antagonist family
BG04_2503	COG1366	Belongs to the anti-sigma-factor antagonist family
BG04_2504	COG2172	sigma factor antagonist activity
BG04_2505	COG2208	phosphoserine phosphatase activity
BG04_2506	COG1366	Belongs to the anti-sigma-factor antagonist family
BG04_2508	COG1191	sigma factor activity
BG04_2509	COG2208	phosphoserine phosphatase activity
BG04_251	COG0425	Belongs to the sulfur carrier protein TusA family
BG04_2510	COG2183	response to ionizing radiation
BG04_252	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BG04_252	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BG04_2528	COG0802	atpase or kinase
BG04_2529	COG1214	PFAM Peptidase M22, glycoprotease
BG04_253	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BG04_253	COG0425	Belongs to the sulfur carrier protein TusA family
BG04_2530	COG0456	acetyltransferase
BG04_2532	COG0488	(ABC) transporter
BG04_2533	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BG04_2534	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BG04_2535	COG0805	protein transport
BG04_2537	COG1266	CAAX protease self-immunity
BG04_2538	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BG04_2539	COG0459	protein refolding
BG04_2540	COG2204	response regulator
BG04_2542	COG1454	alcohol dehydrogenase
BG04_2543	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BG04_2544	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BG04_2547	COG0657	acetylesterase activity
BG04_2547	COG2755	lipolytic protein G-D-S-L family
BG04_2548	COG1028	Short-chain dehydrogenase reductase Sdr
BG04_2549	COG0714	Associated with various cellular activities
BG04_2550	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BG04_2551	COG1305	Transglutaminase-like
BG04_2552	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BG04_2552	COG0519	Catalyzes the synthesis of GMP from XMP
BG04_2553	COG2252	PERMEase
BG04_256	COG2210	Belongs to the sulfur carrier protein TusA family
BG04_2561	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BG04_2562	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BG04_2563	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BG04_2564	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BG04_2565	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BG04_2566	COG0047	phosphoribosylformylglycinamidine synthase activity
BG04_2567	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BG04_2568	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BG04_2569	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BG04_257	COG0425	Belongs to the sulfur carrier protein TusA family
BG04_2570	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BG04_2571	COG0138	bifunctional purine biosynthesis protein purh
BG04_2572	COG0151	Belongs to the GarS family
BG04_2574	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BG04_2575	COG4496	protein, YerC YecD
BG04_2576	COG0423	glycine-tRNA ligase activity
BG04_2578	COG0210	DNA helicase
BG04_258	COG1937	Protein conserved in bacteria
BG04_2580	COG4851	CamS sex pheromone cAM373 precursor
BG04_2582	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BG04_2583	COG0154	amidase activity
BG04_2585	COG1597	lipid kinase activity
BG04_2589	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BG04_2591	COG0166	Belongs to the GPI family
BG04_2592	COG1744	ABC transporter substrate-binding protein PnrA-like
BG04_2593	COG3852	Histidine kinase
BG04_2594	COG0024	Methionine aminopeptidase
BG04_2595	COG2706	6-phosphogluconolactonase activity
BG04_2597	COG4978	Transcriptional regulator
BG04_2597	COG0789	Transcriptional regulator
BG04_2598	COG2814	Major facilitator Superfamily
BG04_2600	COG1876	peptidase activity
BG04_2601	COG1126	abc transporter atp-binding protein
BG04_2602	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BG04_2603	COG0765	amino acid transport
BG04_2604	COG0765	amino acid transport
BG04_2605	COG1113	amino acid transport
BG04_2606	COG2733	membrane
BG04_2607	COG3212	peptidase
BG04_2608	COG3212	peptidase
BG04_2609	COG3850	Histidine kinase
BG04_2609	COG5002	protein histidine kinase activity
BG04_2610	COG0745	RESPONSE REGULATOR receiver
BG04_2611	COG2205	protein histidine kinase activity
BG04_2612	COG0745	RESPONSE REGULATOR receiver
BG04_2613	COG2311	Membrane
BG04_2616	COG0671	phosphoesterase, PA-phosphatase related
BG04_2617	COG1764	response to oxidative stress
BG04_2618	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BG04_2620	COG2259	Doxx family
BG04_2621	COG0693	protein deglycase activity
BG04_2622	COG2318	DinB family
BG04_2624	COG1115	amino acid carrier protein
BG04_2627	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BG04_2628	COG0598	Magnesium transport protein CorA
BG04_2629	COG3290	protein histidine kinase activity
BG04_263	COG0583	DNA-binding transcription factor activity
BG04_2630	COG4565	transcriptional regulatory protein
BG04_2633	COG4191	Histidine kinase
BG04_2634	COG0513	Belongs to the DEAD box helicase family
BG04_2638	COG4842	Belongs to the WXG100 family
BG04_2639	COG5417	Belongs to the EsaB family
BG04_2640	COG4499	WXG100 protein secretion system (Wss), protein YukC
BG04_2641	COG0433	COG0433 Predicted ATPase
BG04_2641	COG1674	ftsk spoiiie
BG04_2642	COG1511	domain protein
BG04_2645	COG2356	endonuclease I
BG04_2647	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BG04_2650	COG0488	(ABC) transporter
BG04_2652	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BG04_2654	COG1959	2 iron, 2 sulfur cluster binding
BG04_2655	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BG04_2655	COG1017	nitric oxide dioxygenase activity
BG04_2656	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BG04_2657	COG0693	protein deglycase activity
BG04_2658	COG2340	Cysteine-rich secretory protein family
BG04_2659	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BG04_2660	COG4840	Belongs to the UPF0435 family
BG04_2661	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BG04_2662	COG4980	gas vesicle protein
BG04_2663	COG1295	ribonuclease BN
BG04_2665	COG2217	Heavy metal translocating P-type atpase
BG04_2667	COG0640	Transcriptional regulator
BG04_2669	COG0477	Major facilitator Superfamily
BG04_2670	COG3479	Phenolic acid decarboxylase
BG04_2674	COG0387	Pfam Sodium calcium exchanger
BG04_2676	COG0535	radical SAM domain protein
BG04_268	COG2188	Transcriptional regulator
BG04_2680	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BG04_2681	COG1113	amino acid transport
BG04_2682	COG5002	protein histidine kinase activity
BG04_2686	COG1090	epimerase
BG04_2688	COG4221	oxidoreductase activity
BG04_2692	COG1988	membrane-bound metal-dependent
BG04_2693	COG1194	a g-specific adenine glycosylase
BG04_2695	COG1028	Short-chain dehydrogenase reductase Sdr
BG04_2698	COG3557	Belongs to the UPF0374 family
BG04_2699	COG1132	(ABC) transporter
BG04_27	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BG04_270	COG2723	6-phospho-beta-galactosidase activity
BG04_2700	COG4129	membrane
BG04_2701	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BG04_2702	COG4555	ABC transporter
BG04_2706	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BG04_2707	COG0735	belongs to the Fur family
BG04_2730	COG3382	B3 4 domain protein
BG04_2733	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BG04_2735	COG2766	serine protein kinase
BG04_2738	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BG04_2741	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BG04_2743	COG1968	undecaprenyl-diphosphatase activity
BG04_2744	COG1301	dicarboxylic acid transport
BG04_2746	COG0586	Pfam SNARE associated Golgi protein
BG04_2747	COG2217	Heavy metal translocating P-type atpase
BG04_2748	COG0531	amino acid
BG04_2752	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BG04_2754	COG1175	transmembrane transport
BG04_2755	COG0395	ABC-type sugar transport system, permease component
BG04_2757	COG0584	glycerophosphoryl diester phosphodiesterase
BG04_276	COG1280	lysine exporter protein (LysE YggA)
BG04_2760	COG4948	Mandelate Racemase Muconate Lactonizing
BG04_2769	COG3583	domain protein
BG04_2769	COG3584	3D domain protein
BG04_277	COG3695	enzyme binding
BG04_2770	COG1876	peptidase activity
BG04_2772	COG3103	Sh3 type 3 domain protein
BG04_2774	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BG04_2774	COG0456	acetyltransferase
BG04_2775	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BG04_2780	COG1609	Transcriptional regulator
BG04_2781	COG2814	Major facilitator Superfamily
BG04_2782	COG0673	inositol 2-dehydrogenase activity
BG04_2787	COG1609	Transcriptional regulator
BG04_279	COG0583	DNA-binding transcription factor activity
BG04_2791	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BG04_2792	COG1522	sequence-specific DNA binding
BG04_2796	COG0477	Major facilitator Superfamily
BG04_2797	COG1187	pseudouridine synthase activity
BG04_28	COG1028	Short-chain dehydrogenase reductase Sdr
BG04_280	COG0346	lactoylglutathione lyase activity
BG04_2800	COG1942	4-Oxalocrotonate Tautomerase
BG04_2801	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BG04_2804	COG2851	Citrate transporter
BG04_2807	COG0084	hydrolase, TatD family'
BG04_2809	COG0628	permease
BG04_2812	COG0604	alcohol dehydrogenase
BG04_2813	COG1620	l-lactate permease
BG04_2815	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BG04_2816	COG0840	transmembrane signaling receptor activity
BG04_2817	COG0564	pseudouridine synthase activity
BG04_2819	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BG04_282	COG3706	GGDEF domain
BG04_2820	COG1376	ErfK ybiS ycfS ynhG family protein
BG04_2821	COG3153	acetyltransferase
BG04_2821	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BG04_2822	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BG04_2823	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BG04_2825	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BG04_2826	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BG04_2827	COG1268	BioY protein
BG04_2829	COG2719	SpoVR family
BG04_283	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BG04_2831	COG1959	2 iron, 2 sulfur cluster binding
BG04_2832	COG0604	alcohol dehydrogenase
BG04_2834	COG1126	abc transporter atp-binding protein
BG04_2835	COG0765	amino acid transport
BG04_2836	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BG04_2837	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BG04_2838	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BG04_2840	COG0352	thiamine-phosphate diphosphorylase activity
BG04_2841	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BG04_2844	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BG04_2845	COG0351	phosphomethylpyrimidine kinase
BG04_2848	COG0702	epimerase
BG04_2849	COG1253	flavin adenine dinucleotide binding
BG04_2852	COG3842	ATPase activity
BG04_2853	COG2508	Transcriptional regulator
BG04_2856	COG0189	ligase activity
BG04_2857	COG0189	ligase activity
BG04_2859	COG3679	Belongs to the UPF0342 family
BG04_286	COG0778	Nitroreductase
BG04_2860	COG0561	phosphatase activity
BG04_2861	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BG04_2862	COG0318	PFAM AMP-dependent synthetase and ligase
BG04_2863	COG1024	Enoyl-CoA hydratase
BG04_2866	COG4152	abc transporter atp-binding protein
BG04_2867	COG1668	transmembrane transport
BG04_2868	COG3481	metal-dependent phosphohydrolase, HD sub domain
BG04_287	COG1012	belongs to the aldehyde dehydrogenase family
BG04_2870	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BG04_2874	COG1846	Transcriptional regulator
BG04_2877	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BG04_2878	COG1695	Transcriptional regulator
BG04_2879	COG2153	protein acetylation
BG04_2880	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BG04_2880	COG2755	lipolytic protein G-D-S-L family
BG04_2881	COG0537	adenosine 5'-monophosphoramidase activity
BG04_2882	COG1131	(ABC) transporter
BG04_2883	COG4473	ABC transporter
BG04_2885	COG1473	amidohydrolase
BG04_2886	COG0671	phosphoesterase, PA-phosphatase related
BG04_2887	COG3069	C4-dicarboxylate transmembrane transporter activity
BG04_2888	COG2329	Antibiotic biosynthesis monooxygenase
BG04_2889	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BG04_2890	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BG04_2893	COG1309	transcriptional regulator
BG04_2896	COG2972	Histidine kinase
BG04_2899	COG1234	tRNA 3'-trailer cleavage
BG04_290	COG1704	LemA family
BG04_2900	COG0095	Lipoate-protein ligase
BG04_2901	COG0318	PFAM AMP-dependent synthetase and ligase
BG04_2902	COG1024	Enoyl-CoA hydratase
BG04_291	COG0726	polysaccharide deacetylase
BG04_2925	COG0501	Belongs to the peptidase M48B family
BG04_2926	COG2224	Isocitrate lyase
BG04_2928	COG4946	Tricorn protease homolog
BG04_2928	COG0823	Involved in the tonB-independent uptake of proteins
BG04_2928	COG1506	peptidase
BG04_2929	COG0398	Pfam SNARE associated Golgi protein
BG04_2930	COG1028	Short-chain dehydrogenase reductase Sdr
BG04_2931	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BG04_2932	COG1074	ATP-dependent DNA helicase activity
BG04_2933	COG0420	3'-5' exonuclease activity
BG04_2934	COG0419	ATPase involved in DNA repair
BG04_2935	COG1403	HNH endonuclease
BG04_294	COG1733	regulation of RNA biosynthetic process
BG04_2942	COG2311	Membrane
BG04_2945	COG0367	asparagine synthase
BG04_2948	COG1562	ergosterol biosynthetic process
BG04_2949	COG0366	Alpha amylase catalytic
BG04_2949	COG1874	Beta-galactosidase
BG04_295	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BG04_2950	COG1609	Transcriptional regulator
BG04_2951	COG1012	belongs to the aldehyde dehydrogenase family
BG04_2952	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BG04_2953	COG4187	Peptidase family M20/M25/M40
BG04_2954	COG0833	amino acid
BG04_2955	COG3829	transcription factor binding
BG04_2956	COG1028	Short-chain dehydrogenase reductase Sdr
BG04_2957	COG1666	GTP binding
BG04_2958	COG2996	Protein conserved in bacteria
BG04_2959	COG1307	EDD domain protein, DegV family
BG04_296	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BG04_2960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BG04_2963	COG0561	phosphatase activity
BG04_2964	COG2151	metal-sulfur cluster biosynthetic enzyme
BG04_2965	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BG04_2966	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BG04_2967	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BG04_2968	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BG04_297	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BG04_2972	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BG04_2975	COG0542	response to heat
BG04_2978	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BG04_2979	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BG04_2980	COG2084	Dehydrogenase
BG04_2982	COG2267	carboxylic ester hydrolase activity
BG04_2986	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BG04_2987	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BG04_2988	COG5504	Zn-dependent protease
BG04_2989	COG0444	Belongs to the ABC transporter superfamily
BG04_2990	COG4608	Belongs to the ABC transporter superfamily
BG04_2992	COG0601	transmembrane transport
BG04_2995	COG0180	Tryptophanyl-tRNA synthetase
BG04_2996	COG4166	transmembrane transport
BG04_2997	COG0601	transmembrane transport
BG04_2998	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BG04_2999	COG0444	Belongs to the ABC transporter superfamily
BG04_30	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BG04_300	COG2304	oxidoreductase activity
BG04_3000	COG4608	Belongs to the ABC transporter superfamily
BG04_3001	COG0456	acetyltransferase
BG04_3002	COG1113	amino acid transport
BG04_3003	COG0531	amino acid
BG04_3004	COG1393	Belongs to the ArsC family
BG04_3005	COG0583	DNA-binding transcription factor activity
BG04_3008	COG0861	Integral membrane protein TerC family
BG04_3010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BG04_3012	COG1164	Oligoendopeptidase f
BG04_3015	COG2346	COG2346, Truncated hemoglobins
BG04_3016	COG0741	lytic transglycosylase activity
BG04_3017	COG4116	CYTH
BG04_3019	COG2357	RelA SpoT domain protein
BG04_302	COG0346	lactoylglutathione lyase activity
BG04_3020	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BG04_3021	COG0564	pseudouridine synthase activity
BG04_3022	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BG04_3023	COG2239	Acts as a magnesium transporter
BG04_3024	COG0569	domain protein
BG04_3024	COG0475	glutathione-regulated potassium exporter activity
BG04_303	COG2808	Putative FMN-binding domain
BG04_3035	COG0210	DNA helicase
BG04_3037	COG2323	membrane
BG04_3038	COG2153	protein acetylation
BG04_3040	COG2382	esterase
BG04_3042	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BG04_3044	COG1737	Transcriptional regulator
BG04_3045	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BG04_3046	COG1070	Carbohydrate kinase
BG04_3047	COG1953	Uracil, thiamine, allantoin
BG04_3051	COG1522	sequence-specific DNA binding
BG04_3053	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BG04_3056	COG3142	Participates in the control of copper homeostasis
BG04_3057	COG1113	amino acid transport
BG04_3059	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BG04_3060	COG1309	transcriptional regulator
BG04_3061	COG3711	transcriptional antiterminator
BG04_3061	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BG04_3062	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BG04_3063	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BG04_3064	COG1447	Phosphotransferase system cellobiose-specific component IIA
BG04_3065	COG1486	melibiose metabolic process
BG04_3066	COG3275	phosphorelay sensor kinase activity
BG04_3067	COG3279	Response regulator of the LytR AlgR family
BG04_3069	COG1346	cytolysis
BG04_3071	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BG04_3072	COG0243	molybdopterin cofactor binding
BG04_3073	COG2223	nitrite transmembrane transporter activity
BG04_3074	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BG04_3077	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BG04_3079	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
BG04_3079	COG0028	Belongs to the TPP enzyme family
BG04_3082	COG3527	Alpha-acetolactate decarboxylase
BG04_3083	COG0028	Belongs to the TPP enzyme family
BG04_3085	COG4895	conserved protein (DUF2196)
BG04_3087	COG1733	regulation of RNA biosynthetic process
BG04_3088	COG2814	Major facilitator Superfamily
BG04_3089	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BG04_3090	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BG04_3093	COG3052	prosthetic group binding
BG04_3096	COG0784	Response regulator, receiver
BG04_3097	COG4191	Histidine kinase
BG04_3098	COG2066	Belongs to the glutaminase family
BG04_3099	COG1115	amino acid carrier protein
BG04_31	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BG04_310	COG4807	Protein conserved in bacteria
BG04_3100	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BG04_3102	COG4297	protein containing double-stranded beta helix domain
BG04_3103	COG0531	amino acid
BG04_3105	COG1607	acyl-coa hydrolase
BG04_3106	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BG04_3109	COG0390	transport system, permease component
BG04_3110	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BG04_3113	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BG04_3114	COG1136	(ABC) transporter
BG04_3115	COG0577	efflux transmembrane transporter activity
BG04_3117	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BG04_312	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BG04_3120	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BG04_3121	COG0833	amino acid
BG04_3123	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BG04_3124	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BG04_3126	COG0861	Integral membrane protein TerC family
BG04_3127	COG1301	dicarboxylic acid transport
BG04_3128	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BG04_3129	COG3290	protein histidine kinase activity
BG04_313	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BG04_3137	COG1476	TRANSCRIPTIONal
BG04_3139	COG1368	sulfuric ester hydrolase activity
BG04_314	COG1278	Cold shock
BG04_3142	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BG04_3143	COG2040	homocysteine
BG04_3144	COG0179	Fumarylacetoacetate (FAA) hydrolase
BG04_3147	COG2851	Citrate transporter
BG04_3148	COG3290	protein histidine kinase activity
BG04_3149	COG4565	transcriptional regulatory protein
BG04_3150	COG3181	Tripartite tricarboxylate transporter family receptor
BG04_3151	COG0583	DNA-binding transcription factor activity
BG04_3152	COG3180	Ammonia monooxygenase
BG04_3153	COG2226	methyltransferase
BG04_3154	COG4176	ABC-type proline glycine betaine transport system permease component
BG04_3155	COG0517	IMP dehydrogenase activity
BG04_3155	COG4175	Glycine betaine
BG04_3156	COG2113	Glycine betaine
BG04_3157	COG1309	transcriptional regulator
BG04_316	COG1278	Cold shock
BG04_3161	COG0531	amino acid
BG04_3162	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BG04_3165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BG04_3167	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BG04_3168	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BG04_3170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BG04_3176	COG1737	Transcriptional regulator
BG04_3177	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BG04_3177	COG1263	PTS System
BG04_3179	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BG04_318	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BG04_3180	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BG04_3181	COG1116	anion transmembrane transporter activity
BG04_3182	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BG04_3183	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BG04_3185	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BG04_3186	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BG04_3187	COG1733	regulation of RNA biosynthetic process
BG04_3194	COG1511	domain protein
BG04_3196	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BG04_3197	COG1733	regulation of RNA biosynthetic process
BG04_3198	COG0604	alcohol dehydrogenase
BG04_3198	COG3321	synthase
BG04_3199	COG1132	(ABC) transporter
BG04_320	COG0477	Major facilitator Superfamily
BG04_3200	COG1132	(ABC) transporter
BG04_3202	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BG04_3203	COG3162	membrane
BG04_3205	COG1414	Transcriptional regulator
BG04_3206	COG0656	L-ascorbic acid biosynthetic process
BG04_3207	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BG04_3208	COG1846	Transcriptional regulator
BG04_3209	COG1566	PFAM secretion protein HlyD family protein
BG04_3210	COG2814	Major facilitator Superfamily
BG04_3211	COG0655	NAD(P)H dehydrogenase (quinone) activity
BG04_3214	COG1609	Transcriptional regulator
BG04_3215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BG04_3217	COG1129	ABC transporter
BG04_3218	COG1172	Belongs to the binding-protein-dependent transport system permease family
BG04_3219	COG1879	ABC-type sugar transport system periplasmic component
BG04_3220	COG3583	domain protein
BG04_3220	COG3584	3D domain protein
BG04_3221	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BG04_3222	COG1653	transport
BG04_3227	COG0745	RESPONSE REGULATOR receiver
BG04_3227	COG3706	GGDEF domain
BG04_3231	COG0745	RESPONSE REGULATOR receiver
BG04_3232	COG5002	protein histidine kinase activity
BG04_3240	COG0402	S-adenosylhomocysteine deaminase activity
BG04_3241	COG2252	PERMEase
BG04_3243	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BG04_3244	COG1012	belongs to the aldehyde dehydrogenase family
BG04_3246	COG0710	3-dehydroquinate dehydratase activity
BG04_3248	COG1263	PTS System
BG04_3248	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BG04_3249	COG0366	Alpha amylase catalytic
BG04_3250	COG2188	Transcriptional regulator
BG04_3251	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BG04_3252	COG1984	allophanate hydrolase subunit 2
BG04_3253	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BG04_3254	COG1914	H( )-stimulated, divalent metal cation uptake system
BG04_3255	COG1272	protein, Hemolysin III
BG04_3258	COG0778	Nitroreductase
BG04_3259	COG0628	permease
BG04_326	COG0659	secondary active sulfate transmembrane transporter activity
BG04_3263	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BG04_3264	COG2271	Major facilitator Superfamily
BG04_3265	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BG04_3266	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BG04_3267	COG1012	belongs to the aldehyde dehydrogenase family
BG04_3270	COG0439	Biotin carboxylase
BG04_3273	COG0531	amino acid
BG04_3274	COG0402	S-adenosylhomocysteine deaminase activity
BG04_3275	COG1278	Cold shock
BG04_3276	COG2910	NAD(P)H-binding
BG04_3277	COG0673	inositol 2-dehydrogenase activity
BG04_3278	COG0450	alkyl hydroperoxide reductase
BG04_3279	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BG04_3283	COG3706	GGDEF domain
BG04_3283	COG5001	Diguanylate cyclase
BG04_3283	COG2203	Gaf domain
BG04_3283	COG4251	negative regulation of phosphorylation
BG04_3284	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BG04_3285	COG2076	Multidrug Resistance protein
BG04_3286	COG2076	Multidrug Resistance protein
BG04_3300	COG1649	PFAM Uncharacterised BCR, COG1649
BG04_3301	COG1737	Transcriptional regulator
BG04_3305	COG1486	melibiose metabolic process
BG04_3307	COG1447	Phosphotransferase system cellobiose-specific component IIA
BG04_3309	COG2971	BadF BadG BcrA BcrD
BG04_3310	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BG04_3311	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BG04_3313	COG3037	sugar-specific permease SgaT UlaA
BG04_3316	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BG04_3319	COG1376	ErfK ybiS ycfS ynhG family protein
BG04_3320	COG2226	methyltransferase
BG04_3321	COG0583	DNA-binding transcription factor activity
BG04_3323	COG0667	Aldo Keto reductase
BG04_3326	COG0154	amidase activity
BG04_3328	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BG04_333	COG4451	ribulose bisphosphate carboxylase, small
BG04_333	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BG04_3334	COG2199	diguanylate cyclase activity
BG04_3334	COG2200	EAL domain
BG04_3336	COG1733	regulation of RNA biosynthetic process
BG04_3339	COG0385	Bile acid
BG04_3341	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BG04_3343	COG4191	Histidine kinase
BG04_3344	COG0784	Response regulator, receiver
BG04_3347	COG0791	NLP P60 protein
BG04_3347	COG1388	LysM domain
BG04_3349	COG2385	sporulation resulting in formation of a cellular spore
BG04_3350	COG0656	L-ascorbic acid biosynthetic process
BG04_3353	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BG04_3354	COG4948	Mandelate Racemase Muconate Lactonizing
BG04_3361	COG0477	Major facilitator Superfamily
BG04_3362	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BG04_3364	COG0640	Transcriptional regulator
BG04_3365	COG5658	integral membrane protein
BG04_3369	COG3300	MHYT domain
BG04_3369	COG5001	Diguanylate cyclase
BG04_3370	COG0302	gtp cyclohydrolase
BG04_3373	COG5001	Diguanylate cyclase
BG04_3373	COG3300	MHYT domain
BG04_338	COG2312	Erythromycin esterase
BG04_3392	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BG04_3393	COG1396	sequence-specific DNA binding
BG04_3397	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BG04_34	COG0477	Major facilitator Superfamily
BG04_3401	COG1215	transferase activity, transferring glycosyl groups
BG04_341	COG2329	Antibiotic biosynthesis monooxygenase
BG04_3410	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BG04_3411	COG1682	transport, permease protein
BG04_3412	COG1134	teichoic acid transport
BG04_3416	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BG04_3417	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BG04_3418	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BG04_3419	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BG04_342	COG5002	protein histidine kinase activity
BG04_3421	COG0110	maltose O-acetyltransferase activity
BG04_3425	COG1215	transferase activity, transferring glycosyl groups
BG04_343	COG0745	RESPONSE REGULATOR receiver
BG04_3430	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BG04_3433	COG1482	cell wall glycoprotein biosynthetic process
BG04_3434	COG3944	biosynthesis protein
BG04_3435	COG0489	protein tyrosine kinase activity
BG04_3436	COG4464	protein tyrosine phosphatase activity
BG04_3438	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BG04_3439	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BG04_3442	COG1316	TRANSCRIPTIONal
BG04_3444	COG4464	protein tyrosine phosphatase activity
BG04_3446	COG0028	Belongs to the TPP enzyme family
BG04_3447	COG0069	glutamate synthase activity
BG04_3449	COG2084	Dehydrogenase
BG04_3455	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BG04_3456	COG2146	nitrite reductase [NAD(P)H] activity
BG04_3458	COG2116	formate transmembrane transporter activity
BG04_346	COG1131	(ABC) transporter
BG04_3460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BG04_3461	COG4975	Glucose uptake
BG04_3464	COG0534	Mate efflux family protein
BG04_3466	COG0277	FAD linked oxidase domain protein
BG04_3467	COG1316	TRANSCRIPTIONal
BG04_3469	COG0598	Magnesium transport protein CorA
BG04_3470	COG1404	Belongs to the peptidase S8 family
BG04_3474	COG4821	SIS domain
BG04_3476	COG0363	glucosamine-6-phosphate deaminase activity
BG04_3477	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BG04_3478	COG2190	(PTS) system
BG04_3478	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BG04_3478	COG1263	PTS System
BG04_3479	COG1811	Na channel or pump
BG04_3486	COG1131	(ABC) transporter
BG04_3487	COG1253	flavin adenine dinucleotide binding
BG04_3488	COG0789	Transcriptional regulator
BG04_3490	COG0346	lactoylglutathione lyase activity
BG04_3491	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BG04_3491	COG2105	PFAM AIG2 family protein
BG04_35	COG1846	Transcriptional regulator
BG04_3503	COG4187	Peptidase family M20/M25/M40
BG04_3506	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BG04_3506	COG0456	acetyltransferase
BG04_3509	COG2252	PERMEase
BG04_3511	COG3279	Response regulator of the LytR AlgR family
BG04_3512	COG4555	ABC transporter
BG04_3513	COG1668	transmembrane transport
BG04_3515	COG0789	Transcriptional regulator
BG04_3516	COG1846	Transcriptional regulator
BG04_3517	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BG04_3517	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BG04_3521	COG1785	Belongs to the alkaline phosphatase family
BG04_3522	COG3279	Response regulator of the LytR AlgR family
BG04_3523	COG2205	protein histidine kinase activity
BG04_3523	COG0784	Response regulator, receiver
BG04_3524	COG0861	Integral membrane protein TerC family
BG04_3525	COG1191	sigma factor activity
BG04_353	COG3655	Transcriptional regulator
BG04_3531	COG3243	poly(R)-hydroxyalkanoic acid synthase
BG04_3532	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BG04_3536	COG2186	Transcriptional regulator
BG04_3537	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BG04_3539	COG0247	lactate metabolic process
BG04_3540	COG1139	Iron-sulfur cluster binding protein
BG04_3541	COG1556	Lactate utilization protein
BG04_3542	COG5002	protein histidine kinase activity
BG04_3543	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BG04_3545	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BG04_3546	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BG04_3547	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BG04_3548	COG0436	Aminotransferase
BG04_3549	COG1850	ribulose-bisphosphate carboxylase activity
BG04_355	COG0583	DNA-binding transcription factor activity
BG04_3550	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BG04_3551	COG0235	Class ii aldolase
BG04_3552	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BG04_3554	COG1129	ABC transporter
BG04_3555	COG1172	Belongs to the binding-protein-dependent transport system permease family
BG04_356	COG1028	Short-chain dehydrogenase reductase Sdr
BG04_3560	COG1846	Transcriptional regulator
BG04_3562	COG4191	Histidine kinase
BG04_3564	COG0542	response to heat
BG04_3568	COG0300	oxidoreductase activity
BG04_3570	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BG04_3571	COG0720	synthase
BG04_3573	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BG04_3574	COG0702	epimerase
BG04_3576	COG4873	Protein conserved in bacteria
BG04_3580	COG3773	Cell wall hydrolase
BG04_3588	COG0646	methionine synthase
BG04_3588	COG1410	methionine synthase
BG04_3589	COG0646	methionine synthase
BG04_3589	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BG04_359	COG1064	alcohol dehydrogenase
BG04_3590	COG3949	Membrane
BG04_3591	COG0307	riboflavin synthase, alpha
BG04_3593	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BG04_3595	COG3711	transcriptional antiterminator
BG04_3596	COG1263	PTS System
BG04_3596	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BG04_3596	COG2190	(PTS) system
BG04_3599	COG1346	cytolysis
BG04_36	COG0789	Transcriptional regulator
BG04_360	COG0789	Transcriptional regulator
BG04_3601	COG0583	DNA-binding transcription factor activity
BG04_3603	COG0456	acetyltransferase
BG04_3605	COG0778	Nitroreductase
BG04_3606	COG0436	Aminotransferase
BG04_3610	COG0784	Response regulator, receiver
BG04_3610	COG0835	chemotaxis
BG04_3612	COG1376	ErfK ybiS ycfS ynhG family protein
BG04_3613	COG0248	Ppx GppA phosphatase
BG04_3616	COG1408	metallophosphoesterase
BG04_3617	COG1028	Short-chain dehydrogenase reductase Sdr
BG04_3618	COG2200	EAL domain
BG04_3621	COG4703	Protein of unknown function (DUF1797)
BG04_3622	COG0517	IMP dehydrogenase activity
BG04_3623	COG0583	DNA-binding transcription factor activity
BG04_3624	COG2171	N-acyltransferase activity
BG04_3625	COG1473	amidohydrolase
BG04_3627	COG0668	transmembrane transport
BG04_3628	COG0450	alkyl hydroperoxide reductase
BG04_3629	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BG04_363	COG0662	Cupin 2, conserved barrel domain protein
BG04_3630	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BG04_3631	COG1132	(ABC) transporter
BG04_3632	COG1132	(ABC) transporter
BG04_3633	COG0569	domain protein
BG04_3634	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BG04_3636	COG0561	phosphatase activity
BG04_3641	COG0022	dehydrogenase e1 component
BG04_3642	COG0508	dehydrogenase complex catalyzes the overall conversion of
BG04_3645	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BG04_3647	COG1982	Orn Lys Arg decarboxylase major
BG04_3648	COG4476	Belongs to the UPF0223 family
BG04_3649	COG4493	Belongs to the UPF0637 family
BG04_3651	COG0483	inositol monophosphate 1-phosphatase activity
BG04_3656	COG4896	Protein conserved in bacteria
BG04_3659	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BG04_3660	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BG04_3661	COG4838	Belongs to the UPF0358 family
BG04_3662	COG0772	Belongs to the SEDS family
BG04_3663	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BG04_3664	COG1612	heme a metabolic process
BG04_3665	COG0109	protoheme IX farnesyltransferase activity
BG04_367	COG1366	Belongs to the anti-sigma-factor antagonist family
BG04_3670	COG3336	cytochrome c oxidase
BG04_3672	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BG04_3673	COG2340	Cysteine-rich secretory protein family
BG04_3675	COG2738	Putative neutral zinc metallopeptidase
BG04_3676	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BG04_3677	COG1694	Mazg nucleotide pyrophosphohydrolase
BG04_3678	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BG04_3679	COG1803	Methylglyoxal synthase
BG04_368	COG1278	Cold shock
BG04_3680	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BG04_3681	COG0438	transferase activity, transferring glycosyl groups
BG04_3682	COG0617	tRNA 3'-terminal CCA addition
BG04_3683	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BG04_3683	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BG04_3685	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BG04_3686	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BG04_3687	COG1199	ATP-dependent helicase activity
BG04_3687	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BG04_3691	COG0436	Aminotransferase
BG04_3692	COG0017	Asparaginyl-tRNA synthetase
BG04_3693	COG3935	DnaD domain protein
BG04_3694	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BG04_3696	COG4499	WXG100 protein secretion system (Wss), protein YukC
BG04_3696	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BG04_3697	COG3331	DNA recombination
BG04_37	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BG04_370	COG3290	protein histidine kinase activity
BG04_370	COG0840	transmembrane signaling receptor activity
BG04_3707	COG5337	Spore coat protein CotH
BG04_371	COG1876	peptidase activity
BG04_3710	COG0626	cystathionine gamma-synthase activity
BG04_3711	COG0626	cystathionine gamma-synthase activity
BG04_3714	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BG04_3717	COG1278	Cold shock
BG04_3720	COG3706	GGDEF domain
BG04_3722	COG1111	helicase
BG04_3722	COG1205	dead DEAH box helicase
BG04_3723	COG3359	exonuclease
BG04_3725	COG4474	Belongs to the UPF0398 family
BG04_3726	COG3599	regulation of cell shape
BG04_3730	COG4585	Histidine kinase
BG04_3731	COG2197	response regulator
BG04_3732	COG0366	Alpha amylase catalytic
BG04_3733	COG0116	Belongs to the methyltransferase superfamily
BG04_3736	COG1175	transmembrane transport
BG04_3738	COG3842	ATPase activity
BG04_3740	COG1199	ATP-dependent helicase activity
BG04_3741	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BG04_3742	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BG04_3743	COG2233	PERMEase
BG04_3744	COG0583	DNA-binding transcription factor activity
BG04_3745	COG1012	belongs to the aldehyde dehydrogenase family
BG04_3747	COG3424	synthase
BG04_3748	COG1755	Isoprenylcysteine carboxyl methyltransferase
BG04_375	COG0598	Magnesium transport protein CorA
BG04_3750	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BG04_3751	COG3541	Predicted nucleotidyltransferase
BG04_3756	COG0328	RNA-DNA hybrid ribonuclease activity
BG04_3757	COG0328	RNA-DNA hybrid ribonuclease activity
BG04_376	COG1366	Belongs to the anti-sigma-factor antagonist family
BG04_3762	COG2814	Major facilitator Superfamily
BG04_3764	COG2233	PERMEase
BG04_3765	COG2362	D-Aminopeptidase
BG04_3766	COG0601	transmembrane transport
BG04_3767	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BG04_3768	COG0444	Belongs to the ABC transporter superfamily
BG04_3769	COG4166	transmembrane transport
BG04_3770	COG1619	proteins homologs of microcin C7 resistance protein MccF
BG04_3771	COG0791	NLP P60 protein
BG04_3772	COG4608	Belongs to the ABC transporter superfamily
BG04_3776	COG3300	MHYT domain
BG04_3776	COG5001	Diguanylate cyclase
BG04_378	COG1028	Short-chain dehydrogenase reductase Sdr
BG04_3782	COG2197	response regulator
BG04_3783	COG4585	Histidine kinase
BG04_3784	COG3239	Fatty acid desaturase
BG04_3785	COG2205	protein histidine kinase activity
BG04_3787	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BG04_3790	COG0791	NLP P60 protein
BG04_3790	COG1388	LysM domain
BG04_3791	COG1819	glycosyl
BG04_3794	COG2814	Major facilitator Superfamily
BG04_3796	COG1028	Short-chain dehydrogenase reductase Sdr
BG04_3797	COG3964	amidohydrolase
BG04_3801	COG2188	Transcriptional regulator
BG04_3803	COG0434	BtpA family
BG04_3804	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BG04_3806	COG1785	Belongs to the alkaline phosphatase family
BG04_3807	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BG04_3808	COG1404	Belongs to the peptidase S8 family
BG04_381	COG1028	Short-chain dehydrogenase reductase Sdr
BG04_3810	COG1846	Transcriptional regulator
BG04_3811	COG1566	PFAM secretion protein HlyD family protein
BG04_3812	COG2814	Major facilitator Superfamily
BG04_3817	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BG04_3818	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BG04_3819	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BG04_3820	COG1120	ATPase activity
BG04_3824	COG2814	Major facilitator Superfamily
BG04_3828	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BG04_3829	COG1733	regulation of RNA biosynthetic process
BG04_3830	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BG04_3832	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BG04_3834	COG3448	diguanylate cyclase activity
BG04_3834	COG4175	Glycine betaine
BG04_3838	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BG04_3839	COG2208	phosphoserine phosphatase activity
BG04_384	COG4335	DNA alkylation repair
BG04_3841	COG0531	amino acid
BG04_3843	COG1011	Hydrolase
BG04_3844	COG0405	Gamma-glutamyltransferase
BG04_3845	COG1621	beta-fructofuranosidase activity
BG04_3846	COG1621	beta-fructofuranosidase activity
BG04_3847	COG2193	ferroxidase activity
BG04_3848	COG0477	Major facilitator Superfamily
BG04_3849	COG0156	8-amino-7-oxononanoate synthase activity
BG04_385	COG0454	-acetyltransferase
BG04_3850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BG04_3852	COG2814	Major facilitator Superfamily
BG04_3855	COG1012	belongs to the aldehyde dehydrogenase family
BG04_3856	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BG04_3858	COG1280	lysine exporter protein (LysE YggA)
BG04_3859	COG1113	amino acid transport
BG04_3862	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BG04_3868	COG1113	amino acid transport
BG04_3872	COG1609	Transcriptional regulator
BG04_3873	COG2223	nitrite transmembrane transporter activity
BG04_3875	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BG04_3876	COG1621	beta-fructofuranosidase activity
BG04_3877	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BG04_3877	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BG04_3878	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BG04_3879	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BG04_3880	COG3715	PTS system
BG04_3881	COG3716	PTS system mannose fructose sorbose family IID component
BG04_3882	COG1621	beta-fructofuranosidase activity
BG04_3883	COG0024	Methionine aminopeptidase
BG04_3886	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BG04_3888	COG0656	L-ascorbic acid biosynthetic process
BG04_3889	COG2986	histidine ammonia-lyase
BG04_3891	COG1228	amidohydrolase
BG04_3892	COG0010	Belongs to the arginase family
BG04_3893	COG1846	Transcriptional regulator
BG04_3896	COG0473	3-isopropylmalate dehydrogenase activity
BG04_3897	COG1288	antiporter activity
BG04_3898	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BG04_390	COG2186	Transcriptional regulator
BG04_3902	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BG04_3911	COG2364	Membrane
BG04_3912	COG1846	Transcriptional regulator
BG04_3913	COG0456	acetyltransferase
BG04_3914	COG0640	Transcriptional regulator
BG04_3933	COG1388	LysM domain
BG04_3933	COG0791	NLP P60 protein
BG04_3937	COG2318	DinB family
BG04_394	COG3619	membrane
BG04_3946	COG0583	DNA-binding transcription factor activity
BG04_3947	COG2945	thiolester hydrolase activity
BG04_3947	COG0596	Alpha beta hydrolase
BG04_3950	COG1028	Short-chain dehydrogenase reductase Sdr
BG04_3954	COG0586	Pfam SNARE associated Golgi protein
BG04_396	COG1349	DNA-binding transcription factor activity
BG04_3960	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BG04_3962	COG0697	spore germination
BG04_3963	COG4977	sequence-specific DNA binding
BG04_397	COG0561	phosphatase activity
BG04_3974	COG2610	gluconate transmembrane transporter activity
BG04_3976	COG1250	3-hydroxyacyl-CoA dehydrogenase
BG04_3977	COG0697	spore germination
BG04_3978	COG0583	DNA-binding transcription factor activity
BG04_3981	COG1309	transcriptional regulator
BG04_3982	COG0861	Integral membrane protein TerC family
BG04_3984	COG5577	PFAM Coat F domain
BG04_3987	COG1366	Belongs to the anti-sigma-factor antagonist family
BG04_3989	COG1522	sequence-specific DNA binding
BG04_399	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BG04_3990	COG3813	Protein conserved in bacteria
BG04_3995	COG2076	Multidrug Resistance protein
BG04_4003	COG1278	Cold shock
BG04_4005	COG0028	Belongs to the TPP enzyme family
BG04_4014	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BG04_4015	COG2076	Multidrug Resistance protein
BG04_4016	COG0517	IMP dehydrogenase activity
BG04_4018	COG3246	L-lysine catabolic process to acetate
BG04_4019	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BG04_4020	COG2610	gluconate transmembrane transporter activity
BG04_4022	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BG04_4023	COG0583	DNA-binding transcription factor activity
BG04_4024	COG0747	negative chemotaxis
BG04_4025	COG0601	transmembrane transport
BG04_4026	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BG04_4027	COG0444	Belongs to the ABC transporter superfamily
BG04_4028	COG4608	Belongs to the ABC transporter superfamily
BG04_4029	COG0534	Mate efflux family protein
BG04_4033	COG2172	sigma factor antagonist activity
BG04_4035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BG04_4036	COG0477	Major facilitator Superfamily
BG04_4037	COG1414	Transcriptional regulator
BG04_404	COG1280	lysine exporter protein (LysE YggA)
BG04_4040	COG2271	Major facilitator Superfamily
BG04_4041	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BG04_4042	COG0129	dihydroxy-acid dehydratase activity
BG04_4043	COG2610	gluconate transmembrane transporter activity
BG04_4044	COG1388	LysM domain
BG04_4044	COG3858	chitin binding
BG04_4045	COG1376	ErfK ybiS ycfS ynhG family protein
BG04_4052	COG2226	methyltransferase
BG04_4054	COG1733	regulation of RNA biosynthetic process
BG04_4055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BG04_4059	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BG04_4060	COG3420	alginic acid biosynthetic process
BG04_4063	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BG04_4064	COG0640	Transcriptional regulator
BG04_4066	COG0640	Transcriptional regulator
BG04_4069	COG2329	Antibiotic biosynthesis monooxygenase
BG04_4070	COG3545	Serine hydrolase
BG04_4075	COG1695	Transcriptional regulator
BG04_4083	COG1366	Belongs to the anti-sigma-factor antagonist family
BG04_4086	COG1366	Belongs to the anti-sigma-factor antagonist family
BG04_4087	COG3239	Fatty acid desaturase
BG04_4088	COG1278	Cold shock
BG04_4090	COG0513	Belongs to the DEAD box helicase family
BG04_4092	COG1278	Cold shock
BG04_4099	COG1366	Belongs to the anti-sigma-factor antagonist family
BG04_4105	COG1278	Cold shock
BG04_411	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BG04_4115	COG1113	amino acid transport
BG04_4116	COG2318	DinB family
BG04_4118	COG2801	Transposase and inactivated derivatives
BG04_4119	COG2359	stage V sporulation protein S
BG04_4123	COG4974	Belongs to the 'phage' integrase family
BG04_4125	COG1376	ErfK ybiS ycfS ynhG family protein
BG04_4128	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BG04_4129	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BG04_4131	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BG04_4132	COG1587	Uroporphyrinogen-III synthase
BG04_4133	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BG04_4134	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BG04_4137	COG1982	Orn Lys Arg decarboxylase major
BG04_4143	COG0583	DNA-binding transcription factor activity
BG04_4146	COG1994	Peptidase M50
BG04_4148	COG2261	transglycosylase associated protein
BG04_4149	COG3773	Cell wall hydrolase
BG04_415	COG2160	L-arabinose isomerase activity
BG04_4151	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BG04_4158	COG2814	Major facilitator Superfamily
BG04_4161	COG3238	Protein conserved in bacteria
BG04_4165	COG1114	Component of the transport system for branched-chain amino acids
BG04_4167	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BG04_4169	COG0667	Aldo Keto reductase
BG04_4171	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BG04_4171	COG1017	nitric oxide dioxygenase activity
BG04_4173	COG0574	Belongs to the PEP-utilizing enzyme family
BG04_4173	COG3848	Pyruvate phosphate dikinase
BG04_4174	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BG04_4176	COG0477	Major facilitator Superfamily
BG04_418	COG1609	Transcriptional regulator
BG04_4180	COG1012	belongs to the aldehyde dehydrogenase family
BG04_4188	COG0517	IMP dehydrogenase activity
BG04_419	COG1078	dGTPase activity
BG04_4191	COG1309	transcriptional regulator
BG04_4194	COG1070	Carbohydrate kinase
BG04_4195	COG2814	Major facilitator Superfamily
BG04_4195	COG0477	Major facilitator Superfamily
BG04_4196	COG3290	protein histidine kinase activity
BG04_4196	COG3829	transcription factor binding
BG04_4197	COG2851	Citrate transporter
BG04_4202	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BG04_4203	COG1845	cytochrome c oxidase, subunit III
BG04_4205	COG0589	response to stress
BG04_4206	COG1028	Short-chain dehydrogenase reductase Sdr
BG04_4207	COG1612	heme a metabolic process
BG04_4208	COG2072	flavoprotein involved in K transport
BG04_421	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BG04_4210	COG2252	PERMEase
BG04_4211	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BG04_4212	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BG04_4213	COG0022	dehydrogenase e1 component
BG04_4214	COG0508	dehydrogenase complex catalyzes the overall conversion of
BG04_4215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BG04_4216	COG3284	Transcriptional regulator
BG04_4217	COG1063	alcohol dehydrogenase
BG04_4219	COG1846	Transcriptional regulator
BG04_422	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BG04_4223	COG0628	permease
BG04_4224	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BG04_4227	COG2211	Major facilitator Superfamily
BG04_423	COG1918	ferrous iron import across plasma membrane
BG04_423	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BG04_4231	COG0589	response to stress
BG04_4233	COG5002	protein histidine kinase activity
BG04_4235	COG1937	Protein conserved in bacteria
BG04_4236	COG2608	mercury ion transmembrane transporter activity
BG04_4237	COG2217	Heavy metal translocating P-type atpase
BG04_4239	COG1388	LysM domain
BG04_4240	COG2271	Major facilitator Superfamily
BG04_4248	COG0640	Transcriptional regulator
BG04_4249	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BG04_4251	COG2050	protein possibly involved in aromatic compounds catabolism
BG04_4252	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BG04_4253	COG2323	membrane
BG04_4256	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BG04_4257	COG1802	Transcriptional regulator
BG04_4258	COG0473	3-isopropylmalate dehydrogenase activity
BG04_4259	COG2814	Major facilitator Superfamily
BG04_4260	COG1733	regulation of RNA biosynthetic process
BG04_4261	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BG04_4261	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BG04_4262	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BG04_4262	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BG04_4267	COG2264	protein methyltransferase activity
BG04_4269	COG5566	PFAM Mor transcription activator
BG04_4272	COG0561	phosphatase activity
BG04_4273	COG1876	peptidase activity
BG04_4275	COG0726	polysaccharide deacetylase
BG04_4282	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BG04_4285	COG0386	Belongs to the glutathione peroxidase family
BG04_4286	COG1418	mRNA catabolic process
BG04_4287	COG0488	(ABC) transporter
BG04_4288	COG1413	lyase activity
BG04_4289	COG0726	polysaccharide deacetylase
BG04_429	COG1846	Transcriptional regulator
BG04_4291	COG2521	methyltransferase
BG04_4291	COG2136	Putative SAM-dependent methyltransferase
BG04_4293	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BG04_4294	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BG04_4296	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BG04_4299	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BG04_4300	COG0406	alpha-ribazole phosphatase activity
BG04_4302	COG2096	Adenosyltransferase
BG04_4303	COG2962	Rard protein
BG04_4306	COG0523	cobalamin synthesis protein
BG04_4307	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BG04_4308	COG0322	excinuclease ABC activity
BG04_4310	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BG04_4311	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BG04_4312	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BG04_4314	COG3011	Protein conserved in bacteria
BG04_4315	COG1595	DNA-templated transcription, initiation
BG04_4319	COG2002	toxin-antitoxin pair type II binding
BG04_4320	COG0534	Mate efflux family protein
BG04_4321	COG1028	Short-chain dehydrogenase reductase Sdr
BG04_4326	COG1368	sulfuric ester hydrolase activity
BG04_4328	COG3853	Toxic anion resistance protein (TelA)
BG04_4332	COG0726	polysaccharide deacetylase
BG04_4334	COG2234	aminopeptidase activity
BG04_4335	COG5002	protein histidine kinase activity
BG04_4337	COG1823	symporter activity
BG04_4338	COG1523	belongs to the glycosyl hydrolase 13 family
BG04_4339	COG1012	belongs to the aldehyde dehydrogenase family
BG04_4340	COG2124	cytochrome p450
BG04_4340	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BG04_4341	COG2112	serine threonine protein kinase
BG04_4344	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BG04_4345	COG1360	Flagellar Motor Protein
BG04_4348	COG3361	conserved protein (COG2071)
BG04_4349	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BG04_4350	COG1757	Na H antiporter
BG04_4352	COG0833	amino acid
BG04_4353	COG3594	Acyltransferase
BG04_4354	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BG04_4356	COG0745	RESPONSE REGULATOR receiver
BG04_4357	COG5002	protein histidine kinase activity
BG04_4358	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BG04_4359	COG3104	oligopeptide transport
BG04_4361	COG0281	malic enzyme
BG04_4362	COG3493	citrate carrier protein
BG04_4363	COG0561	phosphatase activity
BG04_4364	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BG04_4367	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BG04_4368	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BG04_4369	COG0765	amino acid transport
BG04_437	COG1388	LysM domain
BG04_437	COG0791	NLP P60 protein
BG04_4370	COG0765	amino acid transport
BG04_4371	COG1126	abc transporter atp-binding protein
BG04_4372	COG0196	riboflavin kinase activity
BG04_4373	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BG04_4375	COG0860	N-Acetylmuramoyl-L-alanine amidase
BG04_438	COG2258	MOSC domain
BG04_4383	COG1611	Belongs to the LOG family
BG04_4384	COG0281	malic enzyme
BG04_4385	COG3402	PFAM membrane-flanked domain
BG04_4386	COG3428	Bacterial PH domain
BG04_4389	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BG04_439	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BG04_4390	COG0109	protoheme IX farnesyltransferase activity
BG04_4391	COG4195	phage-related replication protein
BG04_4394	COG0789	Transcriptional regulator
BG04_44	COG1819	glycosyl
BG04_4401	COG0583	DNA-binding transcription factor activity
BG04_4402	COG0070	glutamate synthase
BG04_4402	COG0067	glutamate synthase
BG04_4402	COG0069	glutamate synthase activity
BG04_4403	COG0493	'glutamate synthase
BG04_4407	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BG04_4410	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BG04_4412	COG1846	Transcriptional regulator
BG04_4413	COG1380	Effector of murein hydrolase LrgA
BG04_4414	COG1346	cytolysis
BG04_4415	COG1366	Belongs to the anti-sigma-factor antagonist family
BG04_4418	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BG04_4419	COG0463	Glycosyl transferase, family 2
BG04_4420	COG2246	polysaccharide biosynthetic process
BG04_4421	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BG04_4422	COG0745	RESPONSE REGULATOR receiver
BG04_4424	COG5583	Uncharacterized small protein (DUF2292)
BG04_4426	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BG04_4428	COG4208	sulfate ABC transporter
BG04_4431	COG0745	RESPONSE REGULATOR receiver
BG04_4436	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BG04_4439	COG1349	DNA-binding transcription factor activity
BG04_4440	COG1105	Belongs to the carbohydrate kinase PfkB family
BG04_4441	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BG04_4441	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BG04_4441	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BG04_4442	COG0527	aspartate kinase activity
BG04_4444	COG2032	superoxide dismutase activity
BG04_4447	COG0300	oxidoreductase activity
BG04_4448	COG0640	Transcriptional regulator
BG04_4449	COG1012	belongs to the aldehyde dehydrogenase family
BG04_4450	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BG04_4454	COG0733	neurotransmitter:sodium symporter activity
BG04_4455	COG3773	Cell wall hydrolase
BG04_4459	COG0673	inositol 2-dehydrogenase activity
BG04_4460	COG1082	Xylose isomerase domain protein TIM barrel
BG04_4461	COG2094	Belongs to the DNA glycosylase MPG family
BG04_4462	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BG04_4464	COG0454	-acetyltransferase
BG04_4466	COG2814	Major facilitator Superfamily
BG04_4469	COG3871	stress protein (general stress protein 26)
BG04_447	COG4974	Belongs to the 'phage' integrase family
BG04_4474	COG1595	DNA-templated transcription, initiation
BG04_4475	COG4873	Protein conserved in bacteria
BG04_4476	COG0714	Associated with various cellular activities
BG04_4477	COG4548	von Willebrand factor, type A
BG04_4478	COG0697	spore germination
BG04_4480	COG2207	Transcriptional regulator
BG04_4481	COG1994	Peptidase M50
BG04_4482	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BG04_4483	COG1119	ATPase activity
BG04_4486	COG1657	PFAM Prenyltransferase squalene oxidase
BG04_4488	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BG04_4488	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BG04_4490	COG0384	phenazine biosynthesis protein PhzF
BG04_4493	COG1378	Sugar-specific transcriptional regulator TrmB
BG04_4494	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BG04_4495	COG1028	Short-chain dehydrogenase reductase Sdr
BG04_4498	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BG04_4500	COG1279	arginine transmembrane transporter activity
BG04_4504	COG2814	Major facilitator Superfamily
BG04_4505	COG2814	Major facilitator Superfamily
BG04_4507	COG3541	Predicted nucleotidyltransferase
BG04_4510	COG1396	sequence-specific DNA binding
BG04_4513	COG0494	nUDIX hydrolase
BG04_4514	COG1335	isochorismatase
BG04_4515	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BG04_4516	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BG04_4517	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BG04_4518	COG1098	S1 RNA binding domain
BG04_4520	COG1404	Belongs to the peptidase S8 family
BG04_4521	COG1028	Short-chain dehydrogenase reductase Sdr
BG04_4522	COG1254	Belongs to the acylphosphatase family
BG04_4523	COG2223	nitrite transmembrane transporter activity
BG04_4524	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BG04_4525	COG4974	Belongs to the 'phage' integrase family
BG04_4528	COG1396	sequence-specific DNA binding
BG04_454	COG1309	transcriptional regulator
BG04_455	COG3844	kynureninase activity
BG04_456	COG1113	amino acid transport
BG04_457	COG3483	tryptophan 2,3-dioxygenase activity
BG04_4570	COG4824	toxin secretion phage lysis holin
BG04_458	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BG04_4582	COG0662	Cupin 2, conserved barrel domain protein
BG04_4582	COG2207	Transcriptional regulator
BG04_4583	COG0697	spore germination
BG04_4584	COG0488	(ABC) transporter
BG04_4585	COG0697	spore germination
BG04_4586	COG0531	amino acid
BG04_4589	COG1131	(ABC) transporter
BG04_459	COG1942	4-Oxalocrotonate Tautomerase
BG04_4590	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BG04_4591	COG1757	Na H antiporter
BG04_4593	COG1609	Transcriptional regulator
BG04_4595	COG1533	DNA photolyase activity
BG04_4599	COG0551	DNA topoisomerase type I activity
BG04_4599	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BG04_4601	COG0446	pyridine nucleotide-disulphide oxidoreductase
BG04_4604	COG1063	alcohol dehydrogenase
BG04_4605	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BG04_4609	COG1757	Na H antiporter
BG04_4610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BG04_4612	COG2720	vancomycin resistance protein
BG04_4625	COG1215	transferase activity, transferring glycosyl groups
BG04_4628	COG0514	ATP-dependent DNA helicase (RecQ)
BG04_4634	COG1575	Belongs to the MenA family. Type 1 subfamily
BG04_4638	COG2814	Major facilitator Superfamily
BG04_4639	COG0583	DNA-binding transcription factor activity
BG04_4640	COG1725	Transcriptional regulator
BG04_4641	COG1131	(ABC) transporter
BG04_4643	COG1595	DNA-templated transcription, initiation
BG04_4646	COG1764	response to oxidative stress
BG04_4647	COG1846	Transcriptional regulator
BG04_465	COG0251	oxidation-reduction process
BG04_4653	COG1388	LysM domain
BG04_4653	COG3584	3D domain protein
BG04_4656	COG5002	protein histidine kinase activity
BG04_4658	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BG04_4659	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BG04_4660	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BG04_4663	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BG04_4666	COG2409	Drug exporters of the RND superfamily
BG04_4667	COG1834	amidinotransferase
BG04_4669	COG1295	ribonuclease BN
BG04_468	COG0431	NADPH-dependent FMN reductase
BG04_4680	COG0110	maltose O-acetyltransferase activity
BG04_4681	COG0346	lactoylglutathione lyase activity
BG04_4683	COG1366	Belongs to the anti-sigma-factor antagonist family
BG04_4685	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BG04_4687	COG2176	DNA-directed DNA polymerase activity
BG04_469	COG0196	riboflavin kinase activity
BG04_4690	COG0114	fumarate hydratase activity
BG04_4692	COG3757	hydrolase, family 25
BG04_4692	COG3409	Peptidoglycan-binding domain 1 protein
BG04_4694	COG5002	protein histidine kinase activity
BG04_47	COG1902	pentaerythritol trinitrate reductase activity
BG04_470	COG2368	4-hydroxyphenylacetate
BG04_4701	COG0778	Nitroreductase
BG04_4703	COG0300	oxidoreductase activity
BG04_4704	COG3290	protein histidine kinase activity
BG04_4705	COG4565	transcriptional regulatory protein
BG04_4706	COG2851	Citrate transporter
BG04_4708	COG2610	gluconate transmembrane transporter activity
BG04_4709	COG1028	Short-chain dehydrogenase reductase Sdr
BG04_4710	COG2195	Cleaves the N-terminal amino acid of tripeptides
BG04_4716	COG0583	DNA-binding transcription factor activity
BG04_4719	COG1301	dicarboxylic acid transport
BG04_4720	COG0019	diaminopimelate decarboxylase activity
BG04_4722	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BG04_4724	COG4191	Histidine kinase
BG04_4727	COG1028	Short-chain dehydrogenase reductase Sdr
BG04_4728	COG0318	PFAM AMP-dependent synthetase and ligase
BG04_4730	COG1250	3-hydroxyacyl-CoA dehydrogenase
BG04_4731	COG1024	Enoyl-CoA hydratase
BG04_4734	COG2045	Belongs to the ComB family
BG04_4735	COG1960	acyl-CoA dehydrogenase activity
BG04_4736	COG1028	Short-chain dehydrogenase reductase Sdr
BG04_4737	COG1024	Enoyl-CoA hydratase
BG04_474	COG0789	Transcriptional regulator
BG04_4740	COG1141	Ferredoxin
BG04_4742	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BG04_4743	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BG04_4744	COG0183	Belongs to the thiolase family
BG04_4745	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BG04_475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BG04_4750	COG1509	lysine 2,3-aminomutase activity
BG04_4752	COG0833	amino acid
BG04_4753	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BG04_4756	COG1979	alcohol dehydrogenase
BG04_4757	COG0738	Major facilitator superfamily
BG04_4759	COG2249	NAD(P)H dehydrogenase (quinone) activity
BG04_476	COG2211	Major facilitator Superfamily
BG04_4760	COG1181	Belongs to the D-alanine--D-alanine ligase family
BG04_4764	COG3977	Valine--pyruvate aminotransferase
BG04_4766	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BG04_4767	COG3773	Cell wall hydrolase
BG04_4768	COG3119	arylsulfatase activity
BG04_4769	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BG04_477	COG1063	alcohol dehydrogenase
BG04_4771	COG0531	amino acid
BG04_4772	COG2814	Major facilitator Superfamily
BG04_4773	COG1846	Transcriptional regulator
BG04_4774	COG2409	Drug exporters of the RND superfamily
BG04_4774	COG1033	growth of symbiont in host cell
BG04_4776	COG3842	ATPase activity
BG04_4777	COG2222	sugar isomerase
BG04_4778	COG1653	transport
BG04_4779	COG1175	transmembrane transport
BG04_478	COG0457	Tetratricopeptide repeat
BG04_4780	COG0395	ABC-type sugar transport system, permease component
BG04_4781	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BG04_4782	COG2188	Transcriptional regulator
BG04_4783	COG1366	Belongs to the anti-sigma-factor antagonist family
BG04_4783	COG2202	Pas domain
BG04_4784	COG3832	glyoxalase III activity
BG04_4785	COG0640	Transcriptional regulator
BG04_4787	COG2267	carboxylic ester hydrolase activity
BG04_4789	COG3386	PFAM SMP-30 Gluconolaconase
BG04_4791	COG2368	4-hydroxyphenylacetate
BG04_4792	COG3739	integral membrane protein
BG04_4794	COG0326	Molecular chaperone. Has ATPase activity
BG04_4795	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BG04_4799	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BG04_4800	COG3757	hydrolase, family 25
BG04_4800	COG3409	Peptidoglycan-binding domain 1 protein
BG04_4802	COG0697	spore germination
BG04_4803	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BG04_4807	COG4572	Cation transport regulator
BG04_4808	COG2015	COG2015, Alkyl sulfatase and related hydrolases
BG04_4810	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BG04_4813	COG3011	Protein conserved in bacteria
BG04_4814	COG1136	(ABC) transporter
BG04_4828	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BG04_4831	COG0494	nUDIX hydrolase
BG04_4832	COG0702	epimerase
BG04_4833	COG0318	PFAM AMP-dependent synthetase and ligase
BG04_4834	COG1846	Transcriptional regulator
BG04_4836	COG2720	vancomycin resistance protein
BG04_4837	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BG04_484	COG5646	InterPro IPR014922
BG04_4844	COG0076	glutamate decarboxylase activity
BG04_4850	COG2116	formate transmembrane transporter activity
BG04_4851	COG5609	conserved protein (DUF2294)
BG04_4854	COG2271	Major facilitator Superfamily
BG04_4855	COG0277	FAD linked oxidase domain protein
BG04_4857	COG0840	transmembrane signaling receptor activity
BG04_4859	COG0622	Phosphoesterase
BG04_4861	COG1408	metallophosphoesterase
BG04_4862	COG3663	DNA glycosylase
BG04_4863	COG3883	PFAM NLP P60 protein
BG04_4863	COG0791	NLP P60 protein
BG04_4864	COG1587	Uroporphyrinogen-III synthase
BG04_4865	COG1414	Transcriptional regulator
BG04_4866	COG0439	Biotin carboxylase
BG04_4867	COG0511	ligase activity, forming carbon-carbon bonds
BG04_4868	COG1984	allophanate hydrolase subunit 2
BG04_4869	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BG04_4870	COG4336	lyase activity
BG04_4871	COG1914	H( )-stimulated, divalent metal cation uptake system
BG04_4872	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BG04_4874	COG3223	Belongs to the PsiE family
BG04_4878	COG2814	Major facilitator Superfamily
BG04_4880	COG0656	L-ascorbic acid biosynthetic process
BG04_4881	COG1028	Short-chain dehydrogenase reductase Sdr
BG04_4882	COG0693	protein deglycase activity
BG04_4883	COG0626	cystathionine gamma-synthase activity
BG04_4884	COG0702	epimerase
BG04_4885	COG1733	regulation of RNA biosynthetic process
BG04_4886	COG2801	Transposase and inactivated derivatives
BG04_4888	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BG04_4891	COG0640	Transcriptional regulator
BG04_4892	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BG04_4893	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BG04_4894	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BG04_4896	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BG04_49	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BG04_4901	COG0572	uridine kinase
BG04_4905	COG2814	Major facilitator Superfamily
BG04_4907	COG1376	ErfK ybiS ycfS ynhG family protein
BG04_4911	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BG04_4912	COG2271	Major facilitator Superfamily
BG04_4913	COG1846	Transcriptional regulator
BG04_4913	COG0456	acetyltransferase
BG04_4916	COG0697	spore germination
BG04_4917	COG0789	Transcriptional regulator
BG04_4918	COG1278	Cold shock
BG04_492	COG2814	Major facilitator Superfamily
BG04_4920	COG0513	Belongs to the DEAD box helicase family
BG04_4923	COG1366	Belongs to the anti-sigma-factor antagonist family
BG04_4928	COG0346	lactoylglutathione lyase activity
BG04_4930	COG4257	antibiotic catabolic process
BG04_494	COG1794	racemase activity, acting on amino acids and derivatives
BG04_4942	COG0318	PFAM AMP-dependent synthetase and ligase
BG04_4943	COG1268	BioY protein
BG04_4944	COG0183	Belongs to the thiolase family
BG04_4946	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BG04_4948	COG0431	NADPH-dependent FMN reductase
BG04_4949	COG2197	response regulator
BG04_495	COG4191	Histidine kinase
BG04_4950	COG2203	Gaf domain
BG04_4950	COG4585	Histidine kinase
BG04_4954	COG0697	spore germination
BG04_4956	COG2153	protein acetylation
BG04_4957	COG0129	dihydroxy-acid dehydratase activity
BG04_4958	COG2267	carboxylic ester hydrolase activity
BG04_4959	COG1227	inorganic diphosphatase activity
BG04_4964	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BG04_4966	COG0204	Acyl-transferase
BG04_4967	COG2233	PERMEase
BG04_4970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BG04_4973	COG1914	H( )-stimulated, divalent metal cation uptake system
BG04_4976	COG1846	Transcriptional regulator
BG04_4978	COG4974	Belongs to the 'phage' integrase family
BG04_4983	COG0531	amino acid
BG04_4984	COG4302	ethanolamine ammonia-lyase activity
BG04_4985	COG4303	Ethanolamine ammonia lyase large subunit
BG04_4986	COG4819	ethanolamine utilization protein
BG04_4988	COG0833	amino acid
BG04_4990	COG1247	-acetyltransferase
BG04_4991	COG1335	isochorismatase
BG04_4993	COG3403	YqcI/YcgG family
BG04_4994	COG2267	carboxylic ester hydrolase activity
BG04_4995	COG1280	lysine exporter protein (LysE YggA)
BG04_4996	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BG04_4997	COG0187	DNA topoisomerase II activity
BG04_4998	COG1832	CoA-binding protein
BG04_4999	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BG04_5000	COG4841	protein insertion into membrane
BG04_5001	COG0824	Thioesterase
BG04_5007	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BG04_5008	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BG04_5012	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BG04_5013	COG2801	Transposase and inactivated derivatives
BG04_5022	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BG04_5023	COG2068	MobA-Related Protein
BG04_5024	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BG04_503	COG1366	Belongs to the anti-sigma-factor antagonist family
BG04_5036	COG1183	phosphatidylcholine synthase activity
BG04_5039	COG2814	Major facilitator Superfamily
BG04_5040	COG1683	Conserved Protein
BG04_5041	COG1302	Protein conserved in bacteria
BG04_5044	COG1295	ribonuclease BN
BG04_5046	COG1115	amino acid carrier protein
BG04_5047	COG1115	amino acid carrier protein
BG04_5048	COG2814	Major facilitator Superfamily
BG04_5050	COG2814	Major facilitator Superfamily
BG04_5051	COG0789	Transcriptional regulator
BG04_5053	COG0288	reversible hydration of carbon dioxide
BG04_5054	COG0659	secondary active sulfate transmembrane transporter activity
BG04_5055	COG0745	RESPONSE REGULATOR receiver
BG04_5056	COG5002	protein histidine kinase activity
BG04_5058	COG4282	regulation of fungal-type cell wall biogenesis
BG04_5059	COG0531	amino acid
BG04_5061	COG0860	N-Acetylmuramoyl-L-alanine amidase
BG04_5062	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BG04_5078	COG1363	Peptidase, m42
BG04_5080	COG1114	Component of the transport system for branched-chain amino acids
BG04_5084	COG0004	ammonium transporteR
BG04_5087	COG1252	NADH dehydrogenase
BG04_5088	COG0679	Auxin Efflux Carrier
BG04_5089	COG0281	malic enzyme
BG04_5090	COG1473	amidohydrolase
BG04_5094	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BG04_5095	COG0163	prenyltransferase activity
BG04_5096	COG0583	DNA-binding transcription factor activity
BG04_5097	COG0679	Auxin Efflux Carrier
BG04_5101	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BG04_5102	COG0247	lactate metabolic process
BG04_5103	COG0277	FAD linked oxidase domain protein
BG04_5104	COG3835	regulator
BG04_5105	COG0693	protein deglycase activity
BG04_5107	COG2610	gluconate transmembrane transporter activity
BG04_5111	COG1131	(ABC) transporter
BG04_5113	COG2197	response regulator
BG04_5121	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BG04_5123	COG0586	Pfam SNARE associated Golgi protein
BG04_5124	COG1515	deoxyribonuclease V activity
BG04_5125	COG0584	glycerophosphoryl diester phosphodiesterase
BG04_5126	COG3153	acetyltransferase
BG04_5126	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BG04_5128	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BG04_5129	COG0531	amino acid
BG04_513	COG0772	Belongs to the SEDS family
BG04_5149	COG5444	nuclease activity
BG04_5152	COG0534	Mate efflux family protein
BG04_5153	COG1566	PFAM secretion protein HlyD family protein
BG04_5155	COG1846	Transcriptional regulator
BG04_5156	COG0708	Exodeoxyribonuclease III
BG04_516	COG0598	Magnesium transport protein CorA
BG04_5160	COG0673	inositol 2-dehydrogenase activity
BG04_5161	COG1349	DNA-binding transcription factor activity
BG04_5162	COG3853	Toxic anion resistance protein (TelA)
BG04_5164	COG2310	stress, protein
BG04_5165	COG2310	stress, protein
BG04_5166	COG2310	stress, protein
BG04_5167	COG0737	Belongs to the 5'-nucleotidase family
BG04_517	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BG04_5170	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BG04_5171	COG1131	(ABC) transporter
BG04_5173	COG2084	Dehydrogenase
BG04_5174	COG1278	Cold shock
BG04_5175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BG04_5176	COG0028	Belongs to the TPP enzyme family
BG04_5177	COG1278	Cold shock
BG04_518	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BG04_5184	COG1028	Short-chain dehydrogenase reductase Sdr
BG04_5186	COG0427	acetyl-CoA hydrolase
BG04_5187	COG3279	Response regulator of the LytR AlgR family
BG04_5188	COG2323	membrane
BG04_5189	COG2814	Major facilitator Superfamily
BG04_5190	COG3584	3D domain protein
BG04_5190	COG1388	LysM domain
BG04_5191	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BG04_5196	COG3340	Belongs to the peptidase S51 family
BG04_5199	COG0277	FAD linked oxidase domain protein
BG04_52	COG2814	Major facilitator Superfamily
BG04_521	COG2030	dehydratase
BG04_5212	COG5444	nuclease activity
BG04_5216	COG1486	melibiose metabolic process
BG04_5217	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BG04_5218	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BG04_522	COG4670	ketone body catabolic process
BG04_5221	COG2318	DinB family
BG04_5223	COG0579	oxidoreductase
BG04_524	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BG04_5240	COG1486	melibiose metabolic process
BG04_5248	COG0596	Alpha beta hydrolase
BG04_5249	COG1929	Belongs to the glycerate kinase type-1 family
BG04_525	COG0583	DNA-binding transcription factor activity
BG04_5250	COG2610	gluconate transmembrane transporter activity
BG04_5251	COG3835	regulator
BG04_5255	COG1454	alcohol dehydrogenase
BG04_5256	COG3152	Membrane
BG04_5272	COG1278	Cold shock
BG04_5273	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BG04_5276	COG2095	MarC family integral membrane protein
BG04_5282	COG0822	iron-sulfur transferase activity
BG04_5285	COG2072	flavoprotein involved in K transport
BG04_5286	COG0318	PFAM AMP-dependent synthetase and ligase
BG04_529	COG2814	Major facilitator Superfamily
BG04_5293	COG0531	amino acid
BG04_5295	COG1114	Component of the transport system for branched-chain amino acids
BG04_5296	COG0776	regulation of translation
BG04_5299	COG0531	amino acid
BG04_5301	COG5002	protein histidine kinase activity
BG04_5301	COG3850	Histidine kinase
BG04_5302	COG0745	RESPONSE REGULATOR receiver
BG04_5304	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BG04_531	COG0583	DNA-binding transcription factor activity
BG04_5310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BG04_5311	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BG04_5312	COG3152	Membrane
BG04_5313	COG3152	Membrane
BG04_5317	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BG04_5319	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BG04_5322	COG2390	Transcriptional regulator
BG04_5328	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BG04_533	COG2807	transmembrane transport
BG04_5330	COG1695	Transcriptional regulator
BG04_5331	COG0501	Belongs to the peptidase M48B family
BG04_5332	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BG04_5333	COG1742	UPF0060 membrane protein
BG04_5334	COG2182	Extracellular solute-binding protein
BG04_5338	COG2031	fatty acid transporter
BG04_534	COG0583	DNA-binding transcription factor activity
BG04_5343	COG2391	methyltransferase activity
BG04_5346	COG1979	alcohol dehydrogenase
BG04_5347	COG0583	DNA-binding transcription factor activity
BG04_5351	COG2211	Major facilitator Superfamily
BG04_5357	COG1028	Short-chain dehydrogenase reductase Sdr
BG04_5358	COG1063	alcohol dehydrogenase
BG04_5365	COG0025	NhaP-type Na H and K H
BG04_5367	COG1253	flavin adenine dinucleotide binding
BG04_5370	COG4608	Belongs to the ABC transporter superfamily
BG04_5371	COG0444	Belongs to the ABC transporter superfamily
BG04_5372	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BG04_5373	COG0601	transmembrane transport
BG04_5374	COG0747	negative chemotaxis
BG04_5376	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BG04_5380	COG1525	nuclease
BG04_5382	COG0579	oxidoreductase
BG04_5383	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BG04_5384	COG0561	phosphatase activity
BG04_5387	COG0668	transmembrane transport
BG04_5395	COG2309	aminopeptidase activity
BG04_5396	COG1414	Transcriptional regulator
BG04_5397	COG0179	Fumarylacetoacetate (FAA) hydrolase
BG04_5398	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BG04_5399	COG0277	FAD linked oxidase domain protein
BG04_54	COG1228	amidohydrolase
BG04_540	COG1028	Short-chain dehydrogenase reductase Sdr
BG04_5400	COG0247	lactate metabolic process
BG04_5401	COG0277	FAD linked oxidase domain protein
BG04_5402	COG1620	l-lactate permease
BG04_5407	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BG04_5408	COG1131	(ABC) transporter
BG04_5412	COG1595	DNA-templated transcription, initiation
BG04_5416	COG4682	membrane
BG04_5419	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BG04_542	COG2814	Major facilitator Superfamily
BG04_5420	COG1366	Belongs to the anti-sigma-factor antagonist family
BG04_5421	COG0598	Magnesium transport protein CorA
BG04_5422	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BG04_5424	COG2323	membrane
BG04_5425	COG1876	peptidase activity
BG04_5427	COG5002	protein histidine kinase activity
BG04_5428	COG0745	RESPONSE REGULATOR receiver
BG04_543	COG1082	Xylose isomerase domain protein TIM barrel
BG04_5432	COG0508	dehydrogenase complex catalyzes the overall conversion of
BG04_5433	COG0567	Dehydrogenase, E1 component
BG04_5435	COG2814	Major facilitator Superfamily
BG04_5436	COG1764	response to oxidative stress
BG04_5438	COG2311	Membrane
BG04_544	COG0673	inositol 2-dehydrogenase activity
BG04_5445	COG0410	ABC transporter
BG04_5446	COG0347	Belongs to the P(II) protein family
BG04_5447	COG0004	ammonium transporteR
BG04_5448	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BG04_545	COG0673	inositol 2-dehydrogenase activity
BG04_5451	COG0596	Alpha beta hydrolase
BG04_5454	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BG04_5454	COG0456	acetyltransferase
BG04_5455	COG1960	acyl-CoA dehydrogenase activity
BG04_5463	COG4604	ABC transporter, ATP-binding protein
BG04_5464	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BG04_5465	COG1492	cobalamin metabolic process
BG04_5467	COG0531	amino acid
BG04_5469	COG1028	Short-chain dehydrogenase reductase Sdr
BG04_547	COG1609	Transcriptional regulator
BG04_5470	COG2404	hydrolase activity, acting on ester bonds
BG04_5471	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BG04_5473	COG1609	Transcriptional regulator
BG04_5475	COG2271	Major facilitator Superfamily
BG04_5476	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BG04_5481	COG1233	COG1233 Phytoene dehydrogenase and related
BG04_5482	COG0463	Glycosyl transferase, family 2
BG04_549	COG2205	protein histidine kinase activity
BG04_549	COG0784	Response regulator, receiver
BG04_5492	COG0804	urea catabolic process
BG04_5494	COG0831	urea catabolic process
BG04_5495	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BG04_5496	COG0791	NLP P60 protein
BG04_5496	COG1388	LysM domain
BG04_5497	COG1388	LysM domain
BG04_5497	COG3584	3D domain protein
BG04_5498	COG0778	Nitroreductase
BG04_5499	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BG04_5500	COG0586	Pfam SNARE associated Golgi protein
BG04_5502	COG0400	carboxylic ester hydrolase activity
BG04_5503	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BG04_5504	COG2244	polysaccharide biosynthetic process
BG04_5505	COG0697	spore germination
BG04_5506	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BG04_551	COG5577	PFAM Coat F domain
BG04_5510	COG1132	(ABC) transporter
BG04_5515	COG4195	phage-related replication protein
BG04_5518	COG0783	Belongs to the Dps family
BG04_552	COG1063	alcohol dehydrogenase
BG04_5520	COG5577	PFAM Coat F domain
BG04_5521	COG1253	flavin adenine dinucleotide binding
BG04_5524	COG0516	GMP reductase activity
BG04_5524	COG0517	IMP dehydrogenase activity
BG04_5526	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BG04_5526	COG0723	plastoquinol--plastocyanin reductase activity
BG04_5529	COG0287	Prephenate dehydrogenase
BG04_5531	COG1605	Chorismate mutase
BG04_5531	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BG04_5533	COG2059	Chromate
BG04_5534	COG2059	Chromate
BG04_5536	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BG04_5537	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BG04_5538	COG2508	Transcriptional regulator
BG04_5539	COG0011	TIGRFAM Protein of
BG04_554	COG5577	PFAM Coat F domain
BG04_5540	COG1388	LysM domain
BG04_5540	COG0791	NLP P60 protein
BG04_5541	COG0753	catalase activity
BG04_5544	COG0733	neurotransmitter:sodium symporter activity
BG04_555	COG1366	Belongs to the anti-sigma-factor antagonist family
BG04_5553	COG0730	response to heat
BG04_5554	COG1902	pentaerythritol trinitrate reductase activity
BG04_5558	COG0640	Transcriptional regulator
BG04_5560	COG0778	Nitroreductase
BG04_5563	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BG04_5564	COG4991	sh3 domain protein
BG04_5564	COG3103	Sh3 type 3 domain protein
BG04_5564	COG0860	N-Acetylmuramoyl-L-alanine amidase
BG04_5565	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BG04_5566	COG2002	toxin-antitoxin pair type II binding
BG04_5567	COG2318	DinB family
BG04_5568	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BG04_5571	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BG04_5572	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BG04_5575	COG2211	Major facilitator Superfamily
BG04_5576	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BG04_5577	COG1597	lipid kinase activity
BG04_5579	COG0372	Belongs to the citrate synthase family
BG04_5580	COG0583	DNA-binding transcription factor activity
BG04_5581	COG0697	spore germination
BG04_5582	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BG04_5585	COG1366	Belongs to the anti-sigma-factor antagonist family
BG04_5585	COG2202	Pas domain
BG04_5588	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BG04_5589	COG1733	regulation of RNA biosynthetic process
BG04_5590	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BG04_5591	COG3316	Transposase and inactivated derivatives
BG04_5592	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BG04_5597	COG2323	membrane
BG04_56	COG1316	TRANSCRIPTIONal
BG04_560	COG0517	IMP dehydrogenase activity
BG04_5600	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BG04_5609	COG2801	Transposase and inactivated derivatives
BG04_561	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BG04_5610	COG2124	cytochrome p450
BG04_5615	COG1846	Transcriptional regulator
BG04_5616	COG1741	Belongs to the pirin family
BG04_5617	COG1396	sequence-specific DNA binding
BG04_5619	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BG04_5628	COG2359	stage V sporulation protein S
BG04_5636	COG2801	Transposase and inactivated derivatives
BG04_5646	COG1819	glycosyl
BG04_5649	COG0596	Alpha beta hydrolase
BG04_5653	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BG04_5654	COG0456	acetyltransferase
BG04_5655	COG2801	Transposase and inactivated derivatives
BG04_5670	COG3344	reverse transcriptase
BG04_5677	COG1280	lysine exporter protein (LysE YggA)
BG04_5686	COG1476	TRANSCRIPTIONal
BG04_5689	COG4555	ABC transporter
BG04_569	COG1295	ribonuclease BN
BG04_5692	COG2207	Transcriptional regulator
BG04_5694	COG2226	methyltransferase
BG04_5697	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BG04_5698	COG0204	Acyl-transferase
BG04_57	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BG04_570	COG3264	Mechanosensitive ion channel
BG04_570	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BG04_5702	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BG04_5703	COG0210	DNA helicase
BG04_5707	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BG04_5722	COG1073	alpha beta
BG04_5723	COG4191	Histidine kinase
BG04_5724	COG2197	response regulator
BG04_5743	COG0791	NLP P60 protein
BG04_5743	COG0741	lytic transglycosylase activity
BG04_5759	COG4974	Belongs to the 'phage' integrase family
BG04_5761	COG1376	ErfK ybiS ycfS ynhG family protein
BG04_5769	COG1366	Belongs to the anti-sigma-factor antagonist family
BG04_5780	COG1846	Transcriptional regulator
BG04_5781	COG1741	Belongs to the pirin family
BG04_5782	COG1396	sequence-specific DNA binding
BG04_5784	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BG04_5792	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BG04_5793	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BG04_5795	COG0697	spore germination
BG04_5798	COG3361	conserved protein (COG2071)
BG04_5799	COG0069	glutamate synthase activity
BG04_5801	COG1012	belongs to the aldehyde dehydrogenase family
BG04_5802	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BG04_5807	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BG04_5808	COG3938	Belongs to the proline racemase family
BG04_5809	COG3938	Belongs to the proline racemase family
BG04_581	COG2271	Major facilitator Superfamily
BG04_5810	COG0531	amino acid
BG04_5817	COG0697	spore germination
BG04_5818	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BG04_582	COG4948	Mandelate Racemase Muconate Lactonizing
BG04_5821	COG2002	toxin-antitoxin pair type II binding
BG04_5824	COG1376	ErfK ybiS ycfS ynhG family protein
BG04_584	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BG04_5846	COG1714	RDD family
BG04_585	COG1414	Transcriptional regulator
BG04_5852	COG1819	glycosyl
BG04_5857	COG0658	competence protein
BG04_5857	COG2333	competence protein COMEC
BG04_5860	COG2002	toxin-antitoxin pair type II binding
BG04_5866	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BG04_5873	COG1388	LysM domain
BG04_5882	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BG04_5884	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BG04_5886	COG1396	sequence-specific DNA binding
BG04_5893	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BG04_5901	COG1846	Transcriptional regulator
BG04_5903	COG1902	pentaerythritol trinitrate reductase activity
BG04_5905	COG0840	transmembrane signaling receptor activity
BG04_5906	COG0753	catalase activity
BG04_5907	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BG04_5915	COG0477	Major facilitator Superfamily
BG04_5916	COG1609	Transcriptional regulator
BG04_5917	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BG04_5919	COG2860	membrane
BG04_5920	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BG04_5921	COG2207	Transcriptional regulator
BG04_5922	COG0667	Aldo Keto reductase
BG04_5925	COG2801	Transposase and inactivated derivatives
BG04_5926	COG1733	regulation of RNA biosynthetic process
BG04_5928	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BG04_5929	COG1733	regulation of RNA biosynthetic process
BG04_5930	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BG04_5931	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BG04_5932	COG0300	oxidoreductase activity
BG04_5934	COG1012	belongs to the aldehyde dehydrogenase family
BG04_5938	COG2423	ornithine cyclodeaminase activity
BG04_5939	COG0006	proline dipeptidase activity
BG04_5941	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BG04_5942	COG2508	Transcriptional regulator
BG04_5944	COG1132	(ABC) transporter
BG04_5946	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BG04_5947	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BG04_5948	COG1120	ATPase activity
BG04_5952	COG1131	(ABC) transporter
BG04_5953	COG1309	transcriptional regulator
BG04_5965	COG2801	Transposase and inactivated derivatives
BG04_5969	COG3739	integral membrane protein
BG04_597	COG1396	sequence-specific DNA binding
BG04_5970	COG3655	Transcriptional regulator
BG04_5980	COG5002	protein histidine kinase activity
BG04_5987	COG1393	Belongs to the ArsC family
BG04_5989	COG1404	Belongs to the peptidase S8 family
BG04_599	COG0456	acetyltransferase
BG04_599	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BG04_5993	COG2801	Transposase and inactivated derivatives
BG04_5994	COG3773	Cell wall hydrolase
BG04_5996	COG0477	Major facilitator Superfamily
BG04_5998	COG0500	methyltransferase
BG04_6	COG1366	Belongs to the anti-sigma-factor antagonist family
BG04_6002	COG0477	Major facilitator Superfamily
BG04_6010	COG3773	Cell wall hydrolase
BG04_604	COG2267	carboxylic ester hydrolase activity
BG04_606	COG1335	isochorismatase
BG04_608	COG0346	lactoylglutathione lyase activity
BG04_609	COG2259	Doxx family
BG04_61	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BG04_614	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BG04_615	COG1126	abc transporter atp-binding protein
BG04_616	COG0765	amino acid transport
BG04_618	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BG04_619	COG2222	sugar isomerase
BG04_620	COG2851	Citrate transporter
BG04_622	COG0477	Major facilitator Superfamily
BG04_624	COG0477	Major facilitator Superfamily
BG04_625	COG1309	transcriptional regulator
BG04_63	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BG04_630	COG0156	8-amino-7-oxononanoate synthase activity
BG04_631	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BG04_633	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BG04_633	COG1263	PTS System
BG04_635	COG1378	Sugar-specific transcriptional regulator TrmB
BG04_636	COG0697	spore germination
BG04_637	COG0596	Alpha beta hydrolase
BG04_64	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BG04_640	COG0456	acetyltransferase
BG04_649	COG1266	CAAX protease self-immunity
BG04_652	COG0252	asparaginase activity
BG04_656	COG1695	Transcriptional regulator
BG04_658	COG0583	DNA-binding transcription factor activity
BG04_659	COG2814	Major facilitator Superfamily
BG04_661	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BG04_663	COG0281	malic enzyme
BG04_664	COG2404	hydrolase activity, acting on ester bonds
BG04_678	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BG04_679	COG2076	Multidrug Resistance protein
BG04_683	COG1609	Transcriptional regulator
BG04_685	COG0697	spore germination
BG04_687	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BG04_689	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BG04_7	COG2261	transglycosylase associated protein
BG04_701	COG2207	Transcriptional regulator
BG04_701	COG3708	Transcriptional regulator
BG04_703	COG1971	Probably functions as a manganese efflux pump
BG04_704	COG3339	Conserved Protein
BG04_709	COG2801	Transposase and inactivated derivatives
BG04_710	COG0303	'Molybdopterin
BG04_712	COG0521	Mo-molybdopterin cofactor biosynthetic process
BG04_713	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BG04_718	COG2828	Protein conserved in bacteria
BG04_719	COG0583	DNA-binding transcription factor activity
BG04_720	COG2851	Citrate transporter
BG04_724	COG0670	Belongs to the BI1 family
BG04_728	COG0791	NLP P60 protein
BG04_729	COG2814	Major facilitator Superfamily
BG04_730	COG1846	Transcriptional regulator
BG04_734	COG1278	Cold shock
BG04_738	COG1113	amino acid transport
BG04_739	COG1113	amino acid transport
BG04_740	COG1012	belongs to the aldehyde dehydrogenase family
BG04_741	COG0506	proline dehydrogenase activity
BG04_742	COG3878	Protein conserved in bacteria
BG04_746	COG0860	N-Acetylmuramoyl-L-alanine amidase
BG04_748	COG5001	Diguanylate cyclase
BG04_748	COG3300	MHYT domain
BG04_756	COG5609	conserved protein (DUF2294)
BG04_757	COG3223	Belongs to the PsiE family
BG04_767	COG0789	Transcriptional regulator
BG04_768	COG0667	Aldo Keto reductase
BG04_77	COG1280	lysine exporter protein (LysE YggA)
BG04_770	COG0789	Transcriptional regulator
BG04_775	COG1621	beta-fructofuranosidase activity
BG04_776	COG4980	gas vesicle protein
BG04_78	COG0531	amino acid
BG04_781	COG1752	Esterase of the alpha-beta hydrolase superfamily
BG04_782	COG0577	efflux transmembrane transporter activity
BG04_783	COG1136	(ABC) transporter
BG04_785	COG0642	Histidine kinase
BG04_786	COG0745	RESPONSE REGULATOR receiver
BG04_788	COG1289	transmembrane transporter activity
BG04_789	COG1937	Protein conserved in bacteria
BG04_790	COG3209	COG3209 Rhs family protein
BG04_792	COG3973	AAA domain
BG04_794	COG1024	Enoyl-CoA hydratase
BG04_795	COG1733	regulation of RNA biosynthetic process
BG04_798	COG2124	cytochrome p450
BG04_799	COG2259	Doxx family
BG04_800	COG0463	Glycosyl transferase, family 2
BG04_802	COG0463	Glycosyl transferase, family 2
BG04_806	COG1388	LysM domain
BG04_806	COG0791	NLP P60 protein
BG04_807	COG0840	transmembrane signaling receptor activity
BG04_808	COG1846	Transcriptional regulator
BG04_81	COG3764	Sortase (surface protein transpeptidase)
BG04_810	COG1595	DNA-templated transcription, initiation
BG04_811	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BG04_812	COG0726	polysaccharide deacetylase
BG04_815	COG0833	amino acid
BG04_817	COG0405	Gamma-glutamyltransferase
BG04_819	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BG04_82	COG0730	response to heat
BG04_820	COG0569	domain protein
BG04_822	COG1522	sequence-specific DNA binding
BG04_824	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BG04_825	COG0745	RESPONSE REGULATOR receiver
BG04_826	COG2770	Histidine kinase
BG04_826	COG2205	protein histidine kinase activity
BG04_827	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BG04_828	COG1607	acyl-coa hydrolase
BG04_829	COG1802	Transcriptional regulator
BG04_83	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BG04_830	COG0697	spore germination
BG04_832	COG0006	proline dipeptidase activity
BG04_834	COG1316	TRANSCRIPTIONal
BG04_836	COG2249	NAD(P)H dehydrogenase (quinone) activity
BG04_837	COG5522	Integral membrane protein (intg_mem_TP0381)
BG04_838	COG1174	glycine betaine transport
BG04_839	COG1125	glycine betaine transport
BG04_839	COG0517	IMP dehydrogenase activity
BG04_84	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BG04_843	COG2814	Major facilitator Superfamily
BG04_845	COG0395	ABC-type sugar transport system, permease component
BG04_847	COG1653	transport
BG04_850	COG2205	protein histidine kinase activity
BG04_851	COG0730	response to heat
BG04_852	COG1301	dicarboxylic acid transport
BG04_859	COG1316	TRANSCRIPTIONal
BG04_86	COG2130	NADP-dependent
BG04_860	COG1368	sulfuric ester hydrolase activity
BG04_862	COG0697	spore germination
BG04_863	COG1902	pentaerythritol trinitrate reductase activity
BG04_867	COG1113	amino acid transport
BG04_868	COG5505	Protein of unknown function (DUF819)
BG04_869	COG1309	transcriptional regulator
BG04_871	COG0583	DNA-binding transcription factor activity
BG04_872	COG0730	response to heat
BG04_873	COG1247	-acetyltransferase
BG04_874	COG2910	NAD(P)H-binding
BG04_875	COG1285	pathogenesis
BG04_876	COG2226	methyltransferase
BG04_877	COG4195	phage-related replication protein
BG04_879	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BG04_882	COG1113	amino acid transport
BG04_888	COG0463	Glycosyl transferase, family 2
BG04_893	COG2514	catechol 2,3-dioxygenase activity
BG04_897	COG1280	lysine exporter protein (LysE YggA)
BG04_898	COG1115	amino acid carrier protein
BG04_9	COG1027	Aspartate ammonia-lyase
BG04_900	COG0385	Bile acid
BG04_901	COG0668	transmembrane transport
BG04_902	COG2340	Cysteine-rich secretory protein family
BG04_903	COG1253	flavin adenine dinucleotide binding
BG04_904	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BG04_905	COG0589	response to stress
BG04_907	COG0205	6-phosphofructokinase activity
BG04_908	COG0791	NLP P60 protein
BG04_908	COG1388	LysM domain
BG04_91	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BG04_912	COG0432	Pfam Uncharacterised protein family UPF0047
BG04_913	COG0697	spore germination
BG04_914	COG0814	amino acid
BG04_919	COG1131	(ABC) transporter
BG04_922	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BG04_925	COG0584	glycerophosphoryl diester phosphodiesterase
BG04_927	COG1131	(ABC) transporter
BG04_932	COG1263	PTS System
BG04_932	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BG04_933	COG3711	transcriptional antiterminator
BG04_934	COG2190	(PTS) system
BG04_935	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BG04_938	COG0772	Belongs to the SEDS family
BG04_939	COG0659	secondary active sulfate transmembrane transporter activity
BG04_94	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BG04_940	COG0813	purine-nucleoside phosphorylase activity
BG04_943	COG0671	phosphoesterase, PA-phosphatase related
BG04_945	COG4326	sporulation control protein
BG04_946	COG2815	serine threonine protein kinase
BG04_946	COG0515	serine threonine protein kinase
BG04_950	COG4479	Belongs to the UPF0346 family
BG04_951	COG3594	Acyltransferase
BG04_954	COG1509	lysine 2,3-aminomutase activity
BG04_955	COG0456	acetyltransferase
BG04_956	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BG04_957	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BG04_958	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BG04_959	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BG04_96	COG0501	Belongs to the peptidase M48B family
BG04_960	COG1301	dicarboxylic acid transport
BG04_962	COG4191	Histidine kinase
BG04_968	COG2755	lipolytic protein G-D-S-L family
BG04_969	COG1999	signal sequence binding
BG04_972	COG1307	EDD domain protein, DegV family
BG04_974	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BG04_976	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BG04_977	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BG04_978	COG0788	formyltetrahydrofolate deformylase activity
BG04_986	COG0076	glutamate decarboxylase activity
BG04_990	COG0415	Belongs to the DNA photolyase family
BG04_991	COG3852	Histidine kinase
BG04_995	COG1012	belongs to the aldehyde dehydrogenase family
BG04_997	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BG04_999	COG4846	Membrane protein involved in cytochrome C biogenesis