locus-tag	class	description
C2I28_00055	ENOG41067QW	Transcriptional regulator
C2I28_00060	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
C2I28_00085	ENOG4108XBJ	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity)
C2I28_00100	ENOG4105CHJ	isochorismatase hydrolase
C2I28_00110	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
C2I28_00115	ENOG4108VGI	doxx family
C2I28_00130	ENOG4105C94	Transporter
C2I28_00165	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C2I28_00185	ENOG4105ST3	Transcriptional regulator
C2I28_00195	ENOG4105WS7	Cation transport regulator
C2I28_00200	ENOG4107R3K	hydrolase
C2I28_00205	ENOG4105CG3	alpha amylase, catalytic region
C2I28_00215	ENOG4105U0F	oligosaccharide H symporter, major facilitator superfamily (MFS)
C2I28_00265	ENOG4107FCW	Abortive infection protein
C2I28_00270	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
C2I28_00275	ENOG4105DWV	Homoserine O-trans-acetylase
C2I28_00285	ENOG4105C5Y	PTS System
C2I28_00290	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C2I28_00295	ENOG4107RB3	L-asparaginase
C2I28_00310	ENOG4105DCF	alanine dehydrogenase
C2I28_00325	ENOG4105K7K	Transcriptional regulator
C2I28_00330	ENOG410841Q	phosphoesterase PA-phosphatase related protein
C2I28_00335	ENOG4105GR3	Histidine kinase
C2I28_00340	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C2I28_00345	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C2I28_00360	ENOG4108W5M	transcriptional regulator
C2I28_00370	ENOG4105F27	Major Facilitator
C2I28_00375	ENOG4105DTD	Dehydrogenase
C2I28_00390	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
C2I28_00395	ENOG4105ST3	Transcriptional regulator
C2I28_00400	ENOG4108UW5	maltose o-acetyltransferase
C2I28_00410	ENOG41067QW	Transcriptional regulator
C2I28_00450	ENOG4105YWU	small acid-soluble spore protein
C2I28_00520	ENOG41086D8	Transcriptional regulator
C2I28_00555	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
C2I28_00565	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
C2I28_00580	ENOG4105UIB	(ABC) transporter
C2I28_00585	ENOG4108JQ9	ABC transporter
C2I28_00620	ENOG4105C7F	AcnD-accessory protein PrpF
C2I28_00625	ENOG4108KAM	Transcriptional regulator
C2I28_00650	ENOG4106I4J	membrane
C2I28_00670	ENOG4105K4H	Nlp p60 protein
C2I28_00675	ENOG4105CZM	Major Facilitator
C2I28_00680	ENOG4107MII	Sugar-specific transcriptional regulator TrmB
C2I28_00695	ENOG4105QIV	RNA polymerase
C2I28_00725	ENOG4105C85	amino acid
C2I28_00730	ENOG4105C26	Dehydrogenase
C2I28_00740	ENOG4108XI2	Domain of unknown function (DUF1963)
C2I28_00755	ENOG4108ZRV	stage ii sporulation protein p
C2I28_00760	ENOG4105BZU	Histidine kinase
C2I28_00775	ENOG4107QJZ	Glycosyl transferase, family 2
C2I28_00795	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
C2I28_00805	ENOG4105CTD	carboxy-peptidase
C2I28_00810	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
C2I28_00835	ENOG4105WCN	acetyltransferase
C2I28_00845	ENOG4105VUF	Transcriptional regulator
C2I28_00850	ENOG4105CPC	Aldo Keto reductase
C2I28_00860	ENOG4107SWG	transcriptional regulator MERR family
C2I28_00875	ENOG4108HKT	sucrose-6-phosphate hydrolase
C2I28_00915	ENOG4105C19	ABC transporter
C2I28_00925	ENOG4105EWM	Histidine kinase
C2I28_00930	ENOG4105CJZ	response regulator
C2I28_00940	ENOG4105ME7	Membrane
C2I28_00945	ENOG4105XTG	Pfam:DUF156
C2I28_00950	ENOG4105WFK	nuclease
C2I28_00965	ENOG4105EEM	helicase
C2I28_00970	ENOG4105E39	Enoyl-CoA hydratase
C2I28_00975	ENOG4105KVH	Transcriptional regulator
C2I28_00980	ENOG4106A3M	Cytochrome p-450
C2I28_00990	ENOG4105CKK	Glycosyl transferase, family 2
C2I28_00995	ENOG4107QQG	Dehydrogenase
C2I28_01000	ENOG4105CKK	Glycosyl transferase, family 2
C2I28_01020	ENOG4106YBV	Methyl-accepting chemotaxis
C2I28_01030	ENOG4108P49	AntiSigma factor
C2I28_01035	ENOG4105JVQ	RNA Polymerase
C2I28_01040	ENOG4108ZJ4	polysaccharide deacetylase
C2I28_01055	ENOG4105E1K	spore germination protein
C2I28_01070	ENOG4108IQI	permease
C2I28_01080	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
C2I28_01100	ENOG4105CZN	Potassium uptake protein
C2I28_01105	ENOG4107ZYR	domain protein
C2I28_01125	ENOG4105C0H	protease
C2I28_01135	ENOG4105F3H	Histidine kinase
C2I28_01145	ENOG4108S4H	thioesterase Superfamily protein
C2I28_01150	ENOG4105DRR	Transcriptional regulator, GntR family
C2I28_01160	ENOG41064HX	Suppressor of fused protein (SUFU)
C2I28_01165	ENOG4105DC7	peptidase M24
C2I28_01175	ENOG4108RCF	TRANSCRIPTIONal
C2I28_01185	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
C2I28_01195	ENOG4105E90	ABC transporter
C2I28_01200	ENOG4108IJ8	ABC transporter
C2I28_01215	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C2I28_01225	ENOG4105DRS	transport system, permease
C2I28_01235	ENOG4107YY3	extracellular solute-binding protein family 1
C2I28_01245	ENOG4105ETE	Transcriptional regulator (LacI family
C2I28_01250	ENOG4108HGU	Histidine kinase
C2I28_01255	ENOG4107TSN	permease
C2I28_01260	ENOG4105CK2	sodium dicarboxylate symporter
C2I28_01270	ENOG4105EA8	2-Nitropropane dioxygenase
C2I28_01275	ENOG4105CH6	catalase
C2I28_01295	ENOG4108RCF	TRANSCRIPTIONal
C2I28_01300	ENOG4105E0M	Sulfatase
C2I28_01315	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C2I28_01335	ENOG4105JHY	Membrane
C2I28_01340	ENOG4105J7D	transcriptional regulator
C2I28_01350	ENOG4107RSM	transcriptional regulator
C2I28_01360	ENOG4108Z7F	N-acetyltransferase
C2I28_01365	ENOG4108RYK	Nad-dependent epimerase dehydratase
C2I28_01375	ENOG4105KT7	mgtC SapB transporter
C2I28_01380	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
C2I28_01385	ENOG4105K7W	phage-related replication protein
C2I28_01395	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
C2I28_01410	ENOG4105C85	amino acid
C2I28_01460	ENOG4105C1Q	protoporphyrinogen oxidase
C2I28_01465	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
C2I28_01470	ENOG4107YH7	Beta-lactamase (EC 3.5.2.6)
C2I28_01485	ENOG4108NIW	Leucine export protein LeuE
C2I28_01505	ENOG4105D64	Mechanosensitive ion channel
C2I28_01510	ENOG4105K4I	Scp-like extracellular
C2I28_01515	ENOG4105C37	(CBS) domain
C2I28_01525	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
C2I28_01530	ENOG4107YZX	Universal stress protein
C2I28_01535	ENOG4105CTQ	phosphohexokinase
C2I28_01550	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
C2I28_01565	ENOG4108NHD	germination protein
C2I28_01585	ENOG4105CZV	ABC transporter
C2I28_01600	ENOG4108JYZ	YitT family
C2I28_01615	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
C2I28_01625	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C2I28_01640	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
C2I28_01650	ENOG4105C5Y	PTS System
C2I28_01670	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
C2I28_01690	ENOG4105CHH	sulfate transporter
C2I28_01695	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
C2I28_01700	ENOG4106Z5R	
C2I28_01705	ENOG410841Q	phosphoesterase PA-phosphatase related protein
C2I28_01710	ENOG4108N23	SpoOM-related protein
C2I28_01735	ENOG4105VSD	UPF0346 protein
C2I28_01740	ENOG4108TGC	Acyltransferase
C2I28_01745	ENOG4105F0I	Aminotransferase
C2I28_01755	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
C2I28_01760	ENOG4108TSC	N-acetyltransferase
C2I28_01765	ENOG4107S4Y	M20 DapE family protein YgeY
C2I28_01780	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
C2I28_01795	ENOG4105BZU	Histidine kinase
C2I28_01820	ENOG41090WU	lipolytic protein G-D-S-L family
C2I28_01825	ENOG4108KF3	Electron transport protein SCO1 SenC
C2I28_01835	ENOG4108RCR	degv family
C2I28_01845	ENOG4105C7B	Threonine dehydratase
C2I28_01855	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
C2I28_01860	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
C2I28_01865	ENOG4105CIY	formyltetrahydrofolate deformylase
C2I28_01895	ENOG4105DY8	decarboxylase
C2I28_01915	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
C2I28_01920	ENOG4105BZU	Histidine kinase
C2I28_01935	ENOG4105C26	Dehydrogenase
C2I28_01945	ENOG4108JPW	Aminotransferase
C2I28_01960	ENOG4108U5N	UPF0316 protein
C2I28_01965	ENOG4107QIV	Cytochrome c biogenesis protein
C2I28_01975	ENOG4105BZ1	(ABC) transporter
C2I28_01980	ENOG4105BZ1	(ABC) transporter
C2I28_01985	ENOG4105VXM	UPF0154 protein
C2I28_02000	ENOG4105VPS	UPF0291 protein
C2I28_02005	ENOG4108SVB	resolvase
C2I28_02015	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
C2I28_02040	ENOG4105CKK	Glycosyl transferase, family 2
C2I28_02045	ENOG41076HS	cation diffusion facilitator family transporter
C2I28_02050	ENOG4105C0X	amino acid
C2I28_02060	ENOG4105C5F	glutamine synthetase
C2I28_02065	ENOG4105KV4	Transcriptional regulator
C2I28_02070	ENOG4105CXI	aluminum resistance protein
C2I28_02075	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
C2I28_02080	ENOG4105EN6	Membrane
C2I28_02085	ENOG4106F1P	AAA ATPase, central domain protein
C2I28_02095	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
C2I28_02100	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
C2I28_02105	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
C2I28_02110	ENOG4105CUB	amino acid
C2I28_02125	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
C2I28_02130	ENOG4105DQU	oxidoreductase, subunit beta
C2I28_02135	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
C2I28_02145	ENOG4105MCT	stage V sporulation protein S
C2I28_02150	ENOG4105D48	metallophosphoesterase
C2I28_02160	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
C2I28_02165	ENOG4105CEV	competence damage-inducible protein
C2I28_02170	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
C2I28_02185	ENOG4105XZV	Protein of unknown function (DUF3243)
C2I28_02190	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
C2I28_02210	ENOG4105UIB	(ABC) transporter
C2I28_02215	ENOG4108JQ9	ABC transporter
C2I28_02220	ENOG4105DIH	basic membrane
C2I28_02225	ENOG4105FDP	GntR family transcriptional regulator
C2I28_02230	ENOG4105CNU	cell division protein FtsK
C2I28_02240	ENOG4105CVQ	ATP-dependent Clp protease, proteolytic subunit
C2I28_02250	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
C2I28_02260	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
C2I28_02265	ENOG4108S0H	Dipicolinic acid synthetase, b subunit
C2I28_02270	ENOG4105E35	Dipicolinate synthase subunit A
C2I28_02280	ENOG4105C1V	Peptidase, M16
C2I28_02290	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
C2I28_02295	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
C2I28_02300	ENOG4105DTN	riboflavin biosynthesis protein ribF
C2I28_02315	ENOG4105W7A	Protein of unknown function (DUF503)
C2I28_02320	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
C2I28_02325	ENOG4105VHM	ribosomal protein
C2I28_02330	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
C2I28_02335	ENOG4105CHV	Transcription elongation factor NusA
C2I28_02340	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
C2I28_02345	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
C2I28_02350	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
C2I28_02355	ENOG4105DZP	Membrane-associated zinc metalloprotease
C2I28_02360	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
C2I28_02365	ENOG4105KNE	Phosphatidate cytidylyltransferase
C2I28_02370	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
C2I28_02375	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
C2I28_02385	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
C2I28_02390	ENOG4105CE9	30S ribosomal protein S2
C2I28_02400	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C2I28_02405	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
C2I28_02410	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
C2I28_02415	ENOG4105CBS	Chea signal transduction histidine kinase
C2I28_02420	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
C2I28_02430	ENOG4105FZW	flagellar biosynthesis regulator FlhF
C2I28_02435	ENOG4105D7B	Flagellar biosynthesis protein flha
C2I28_02440	ENOG4105D00	flagellar biosynthetic protein flhB
C2I28_02445	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
C2I28_02450	ENOG4105VS8	Flagellar biosynthetic protein fliq
C2I28_02455	ENOG4105CN7	Flagellar biosynthetic protein FliP
C2I28_02465	ENOG4107YTP	response regulator receiver protein
C2I28_02470	ENOG4105DD5	Flagellar motor switch protein
C2I28_02475	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
C2I28_02485	ENOG41068WV	flagellar FlbD family protein
C2I28_02490	ENOG4108JQA	flagellar
C2I28_02495	ENOG410822I	Flagellar hook capping protein
C2I28_02510	ENOG4106YF4	Flagellar biosynthesis chaperone
C2I28_02525	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
C2I28_02530	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
C2I28_02535	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
C2I28_02540	ENOG4108ZC9	flagellar basal-body rod protein flgc
C2I28_02545	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
C2I28_02550	ENOG4105EUM	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (By similarity)
C2I28_02555	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
C2I28_02560	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
C2I28_02565	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C2I28_02570	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
C2I28_02575	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
C2I28_02580	ENOG4105C79	DNA protecting protein DprA
C2I28_02585	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
C2I28_02590	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
C2I28_02610	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
C2I28_02620	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
C2I28_02630	ENOG4105VB6	UPF0109 protein
C2I28_02635	ENOG4105K5M	30s ribosomal protein S16
C2I28_02645	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
C2I28_02650	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
C2I28_02655	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
C2I28_02660	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
C2I28_02665	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
C2I28_02670	ENOG4105CHR	reductase
C2I28_02675	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
C2I28_02680	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
C2I28_02685	ENOG4108VVV	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity)
C2I28_02690	ENOG4105CB5	ATP-dependent DNA helicase recG
C2I28_02695	ENOG4105EJQ	L-serine dehydratase
C2I28_02710	ENOG4105DP4	dak2 domain fusion protein ylov
C2I28_02715	ENOG4108ZAA	Alkaline-shock protein
C2I28_02720	ENOG4105VB9	50S ribosomal protein l28
C2I28_02730	ENOG4105FJ0	thiamine
C2I28_02735	ENOG4105DJV	ribulose-phosphate 3-epimerase
C2I28_02740	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
C2I28_02745	ENOG4105D9P	serine threonine protein kinase
C2I28_02750	ENOG4108ZF3	Phosphatase
C2I28_02755	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
C2I28_02760	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
C2I28_02765	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
C2I28_02775	ENOG4105C25	Primosomal protein n'
C2I28_02780	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
C2I28_02790	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
C2I28_02795	ENOG4105KC4	UPF0296 protein
C2I28_02800	ENOG4105DSJ	YicC domain protein
C2I28_02810	ENOG4105F23	Fibronectin-binding protein
C2I28_02815	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
C2I28_02830	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
C2I28_02845	ENOG4105CD3	dihydroorotase
C2I28_02850	ENOG4105CXT	aspartate transcarbamylase
C2I28_02860	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
C2I28_02865	ENOG4105C34	Pseudouridine synthase
C2I28_02870	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
C2I28_02890	ENOG4105DBK	s4 domain protein
C2I28_02895	ENOG41067XK	integral membrane protein
C2I28_02900	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
C2I28_02905	ENOG4105DFA	alanine racemase domain protein
C2I28_02910	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
C2I28_02915	ENOG4105WR5	sporulation protein, YlmC YmxH family
C2I28_02925	ENOG4105DAV	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C2I28_02930	ENOG4108AWX	Sporulation factor SpoIIGA 
C2I28_02935	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
C2I28_02940	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
C2I28_02945	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
C2I28_02950	ENOG4105D4A	Cell wall formation (By similarity)
C2I28_02955	ENOG4105CNI	cell division protein FtsW
C2I28_02960	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
C2I28_02965	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
C2I28_02970	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
C2I28_02975	ENOG4105CJN	penicillin-binding protein
C2I28_02980	ENOG4105CJN	penicillin-binding protein
C2I28_02985	ENOG41068DC	Essential cell division protein (By similarity)
C2I28_02995	ENOG41074B2	UPF0747 protein
C2I28_03010	ENOG4107QX3	carboxylase
C2I28_03015	ENOG4106063	Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit
C2I28_03020	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
C2I28_03025	ENOG4108YG3	N-acetyltransferase
C2I28_03035	ENOG4105E39	Enoyl-CoA hydratase
C2I28_03040	ENOG41067VY	50S ribosomal protein L32
C2I28_03045	ENOG4105KNH	Nucleic acid-binding protein
C2I28_03050	ENOG4105CDE	UPF0348 protein
C2I28_03055	ENOG41063PX	domain protein
C2I28_03060	ENOG4105D78	K07001 NTE family protein
C2I28_03065	ENOG4105H20	Sporulation integral membrane protein YlbJ
C2I28_03070	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
C2I28_03075	ENOG4106H78	methyltransferase
C2I28_03085	ENOG4105WUC	UPF0298 protein
C2I28_03120	ENOG4105PE6	Menaquinol-cytochrome c reductase, cytochrome b c subunit
C2I28_03125	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
C2I28_03130	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
C2I28_03140	ENOG4108SXZ	UPF0302 protein
C2I28_03145	ENOG41068YB	TPR repeat-containing protein
C2I28_03155	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
C2I28_03165	ENOG4105CIH	Imidazole acetol-phosphate transaminase
C2I28_03170	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
C2I28_03180	ENOG4105DK0	Indole-3-glycerol phosphate synthase
C2I28_03185	ENOG4108I0Q	anthranilate phosphoribosyltransferase
C2I28_03195	ENOG4105D49	3-dehydroquinate synthase
C2I28_03200	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
C2I28_03205	ENOG4105BZU	Histidine kinase
C2I28_03210	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
C2I28_03215	ENOG4105EAH	synthase
C2I28_03220	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
C2I28_03225	ENOG4105XXQ	heptaprenyl diphosphate synthase component I
C2I28_03230	ENOG4105WP2	Tryptophan RNA-binding attenuator protein
C2I28_03235	ENOG4105EUJ	GTP cyclohydrolase i
C2I28_03240	ENOG4105K70	DNA-binding protein
C2I28_03245	ENOG4105DXU	ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity)
C2I28_03260	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
C2I28_03280	ENOG4105DJB	Major Facilitator Superfamily
C2I28_03285	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
C2I28_03290	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
C2I28_03295	ENOG4105E9Q	Acyl-transferase
C2I28_03300	ENOG4105CAT	Cytidine monophosphate kinase
C2I28_03310	ENOG4105MSI	germination protein ypeb
C2I28_03315	ENOG4105F0V	Cell wall hydrolase
C2I28_03325	ENOG4107RB3	L-asparaginase
C2I28_03330	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
C2I28_03340	ENOG4108S6Z	Negative regulator of genetic competence
C2I28_03345	ENOG4108XDN	Transcriptional regulator
C2I28_03350	ENOG4107RGJ	metallophosphoesterase
C2I28_03365	ENOG4105I7S	Abortive infection protein
C2I28_03370	ENOG4105C9U	ATP-dependent DNA helicase RecQ
C2I28_03385	ENOG4108SAX	Membrane
C2I28_03390	ENOG4108JQ1	Dehydrogenase
C2I28_03395	ENOG4105DR5	peptidase
C2I28_03400	ENOG4105BZU	Histidine kinase
C2I28_03405	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C2I28_03410	ENOG4105CRE	cytochrome C
C2I28_03415	ENOG4107TWT	Cytochrome c biogenesis protein
C2I28_03420	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C2I28_03425	ENOG4105FE9	pseudouridine synthase
C2I28_03435	ENOG4108JIC	nucleoside recognition domain protein
C2I28_03440	ENOG4105DZ1	carboxypeptidase
C2I28_03445	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
C2I28_03450	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
C2I28_03470	ENOG4107ZE5	PPIases accelerate the folding of proteins
C2I28_03475	ENOG4105PTM	secreted protein
C2I28_03490	ENOG4105G6R	Stage v sporulation protein ae
C2I28_03500	ENOG4105CZ3	stage V sporulation protein ad
C2I28_03505	ENOG41090VF	Stage v sporulation protein ac
C2I28_03520	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C2I28_03525	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
C2I28_03530	ENOG41082AN	stage II sporulation protein
C2I28_03535	ENOG4105DZ1	carboxypeptidase
C2I28_03550	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C2I28_03560	ENOG4105I3K	Ferric uptake regulator, Fur family
C2I28_03565	ENOG4105MZ9	stage II sporulation protein m
C2I28_03570	ENOG4108YZ4	nudix hydrolase
C2I28_03580	ENOG4105CPC	Aldo Keto reductase
C2I28_03595	ENOG4105D6N	CoA-transferase, subunit a
C2I28_03600	ENOG4105CHU	acetyl-coa acetyltransferase
C2I28_03605	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
C2I28_03625	ENOG4108IXY	short-chain dehydrogenase reductase
C2I28_03630	ENOG41069FQ	Metallo-beta-lactamase superfamily
C2I28_03635	ENOG4105II7	pyrroline-5-carboxylate reductase
C2I28_03640	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C2I28_03645	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
C2I28_03650	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
C2I28_03655	ENOG4105C26	Dehydrogenase
C2I28_03660	ENOG4105G9B	Transcriptional regulator
C2I28_03680	ENOG4107SJI	Dehydrogenase
C2I28_03685	ENOG4105BZ8	glutamate synthase
C2I28_03690	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
C2I28_03695	ENOG4108HNZ	carboxyl transferase
C2I28_03705	ENOG4108VZI	ErfK ybiS ycfS ynhG family protein
C2I28_03710	ENOG4108QEG	Membrane
C2I28_03715	ENOG4105CDA	abc transporter atp-binding protein
C2I28_03720	ENOG4105E5Q	amino acid AbC transporter
C2I28_03725	ENOG4108HW3	(ABC) transporter
C2I28_03735	ENOG4105DJT	lAO AO transport system ATPase
C2I28_03740	ENOG4105D5P	Methylmalonyl-coA mutase
C2I28_03750	ENOG4105C7S	Dehydrogenase
C2I28_03755	ENOG4105CPP	Dehydrogenase, E1 component
C2I28_03775	ENOG4107RDP	Dehydrogenase
C2I28_03785	ENOG4108JUB	Transcriptional regulator
C2I28_03790	ENOG4106CCJ	Protein of unknown function (DUF2627)
C2I28_03795	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
C2I28_03805	ENOG4105DUX	Transporter
C2I28_03810	ENOG4107QQR	Sporulation
C2I28_03815	ENOG4105S1Z	Stage IV sporulation protein B
C2I28_03820	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
C2I28_03830	ENOG4105DX0	Hemolysin A
C2I28_03845	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
C2I28_03855	ENOG4105M7K	Involved in the transcription termination process (By similarity)
C2I28_03860	ENOG4108ZSR	alkaline shock protein
C2I28_03865	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
C2I28_03885	ENOG410644B	Stage III sporulation protein af
C2I28_03895	ENOG4105KQ4	Stage iii sporulation protein ad
C2I28_03900	ENOG4108CQH	stage III sporulation protein AC
C2I28_03905	ENOG4105KR5	Stage iii sporulation protein
C2I28_03910	ENOG4105CD2	stage iii sporulation protein aa
C2I28_03920	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
C2I28_03925	ENOG4105DC7	peptidase M24
C2I28_03930	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
C2I28_03940	ENOG4105CBJ	Metal-dependent enzyme
C2I28_03955	ENOG4105KST	dependent repressor
C2I28_03960	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C2I28_03965	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
C2I28_03970	ENOG4105WZW	rhodanese family
C2I28_03980	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C2I28_03985	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
C2I28_03990	ENOG4105C0D	helicase
C2I28_04050	ENOG4105C5X	domain protein
C2I28_04065	ENOG4105DKQ	ROK family
C2I28_04075	ENOG4107ZXI	Rhomboid family
C2I28_04085	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
C2I28_04090	ENOG410861F	50S ribosomal protein L33
C2I28_04110	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
C2I28_04115	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
C2I28_04120	ENOG4107RF6	penicillin-binding protein
C2I28_04160	ENOG4105SXS	Protein of unknown function (DUF456)
C2I28_04175	ENOG4107RCC	Major Facilitator Superfamily
C2I28_04185	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
C2I28_04190	ENOG41063Y9	
C2I28_04195	ENOG4108U5J	'-nucleotidase
C2I28_04200	ENOG4105N80	Ferric uptake regulator, Fur family
C2I28_04205	ENOG4105FAV	ABC, transporter
C2I28_04210	ENOG4105FDK	ABC transporter
C2I28_04220	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
C2I28_04235	ENOG4108IUH	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
C2I28_04240	ENOG4105EGD	dinuclear metal center protein, YbgI family
C2I28_04255	ENOG4105C1G	acyl-Coa dehydrogenase
C2I28_04260	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C2I28_04265	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
C2I28_04270	ENOG4107XJU	UPF0178 protein
C2I28_04275	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
C2I28_04285	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
C2I28_04295	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
C2I28_04300	ENOG4105KG3	cytidine deaminase
C2I28_04305	ENOG4107YR5	Diacylglycerol kinase
C2I28_04310	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
C2I28_04315	ENOG4105CTJ	Metal Dependent Phosphohydrolase
C2I28_04320	ENOG4105C9A	Phoh family
C2I28_04330	ENOG41068P3	sporulation protein YqfC
C2I28_04345	ENOG4105F7J	membrane-bound serine protease
C2I28_04350	ENOG4105KTH	gatB Yqey
C2I28_04360	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
C2I28_04365	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
C2I28_04370	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
C2I28_04375	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
C2I28_04385	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C2I28_04390	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
C2I28_04395	ENOG4105CSA	Coproporphyrinogen iii oxidase
C2I28_04400	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
C2I28_04415	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
C2I28_04420	ENOG4105TQK	DNA polymerase iii, delta' subunit
C2I28_04430	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
C2I28_04435	ENOG4108UK2	deaminase
C2I28_04440	ENOG4105KQC	Competence protein
C2I28_04450	ENOG4105DXX	methyltransferase
C2I28_04455	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
C2I28_04460	ENOG4108WF2	Metal Dependent Phosphohydrolase
C2I28_04465	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
C2I28_04470	ENOG410812S	Rna-binding protein
C2I28_04475	ENOG4105E2X	shikimate dehydrogenase
C2I28_04480	ENOG4105CQW	ribosome biogenesis GTPase YqeH
C2I28_04485	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
C2I28_04495	ENOG4105DJ4	phosphatidylserine decarboxylase
C2I28_04500	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
C2I28_04505	ENOG4105DMD	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C2I28_04520	ENOG4105C28	cystathionine
C2I28_04530	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
C2I28_04535	ENOG4108WVK	Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity)
C2I28_04550	ENOG4107XRG	penicillin-binding protein
C2I28_04555	ENOG4105D3W	isochorismatase
C2I28_04560	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
C2I28_04565	ENOG4105DBI	uridine monophosphokinase
C2I28_04570	ENOG4105CFP	Peptidase U32
C2I28_04575	ENOG4105XYU	peptidase (U32 family)
C2I28_04580	ENOG4108VQJ	O-methyltransferase
C2I28_04585	ENOG4105HHA	aminodeoxychorismate lyase
C2I28_04590	ENOG4105VPH	UPF0473 protein
C2I28_04600	ENOG4105VBH	UPF0297 protein
C2I28_04605	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
C2I28_04610	ENOG4105C02	permease
C2I28_04620	ENOG41060CR	
C2I28_04625	ENOG4105C7H	Helicase, RecD TraA family
C2I28_04635	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
C2I28_04640	ENOG4105C3J	Cysteine desulfurase
C2I28_04650	ENOG4105D1H	recombination factor protein RarA
C2I28_04655	ENOG4105E2Z	phosphate ABC transporter (Permease
C2I28_04660	ENOG4105C8U	phosphate abc transporter
C2I28_04665	ENOG4105CVA	phosphate
C2I28_04670	ENOG4105CUZ	uba thif-type nad fad binding protein
C2I28_04680	ENOG4105C9M	aspartyl-trna synthetase
C2I28_04685	ENOG4105CUT	histidyl-tRNA synthetase
C2I28_04695	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
C2I28_04700	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
C2I28_04705	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
C2I28_04710	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
C2I28_04715	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
C2I28_04720	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C2I28_04730	ENOG4105CKP	Polysaccharide Biosynthesis Protein
C2I28_04735	ENOG4108QG2	Membrane
C2I28_04740	ENOG4105NAP	
C2I28_04745	ENOG4105VIE	preprotein translocase, subunit YajC
C2I28_04750	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
C2I28_04755	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
C2I28_04760	ENOG41061AI	Protein of unknown function (DUF2905)
C2I28_04765	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
C2I28_04770	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
C2I28_04795	ENOG4106678	morphogenetic protein associated with SpoVID
C2I28_04800	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
C2I28_04805	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
C2I28_04810	ENOG4108IYU	L-aspartate oxidase
C2I28_04825	ENOG4105CQC	Prephenate dehydratase
C2I28_04830	ENOG41090I5	UPF0735 ACT domain-containing protein
C2I28_04835	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C2I28_04845	ENOG4105K46	50S ribosomal protein l27
C2I28_04850	ENOG4105X36	(ribosomal) protein
C2I28_04860	ENOG4105C03	ribonuclease
C2I28_04875	ENOG4107QMS	site-determining protein
C2I28_04880	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
C2I28_04885	ENOG4105YHC	Rod shape-determining protein MreD
C2I28_04890	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
C2I28_04895	ENOG4105DFF	Rod shape-determining protein mreb
C2I28_04900	ENOG4105W5Q	DNA repair protein (RadC
C2I28_04915	ENOG4106A3R	peptidase
C2I28_04925	ENOG4108SJC	Membrane
C2I28_04930	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
C2I28_04935	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
C2I28_04945	ENOG4106AR7	Spore coat protein
C2I28_04950	ENOG41068KH	stage VI sporulation protein D
C2I28_04955	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
C2I28_04960	ENOG4105D52	delta-aminolevulinic acid dehydratase
C2I28_04970	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
C2I28_04980	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
C2I28_04990	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
C2I28_04995	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
C2I28_05000	ENOG4108IUQ	atp-dependent protease
C2I28_05005	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
C2I28_05010	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
C2I28_05020	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C2I28_05025	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C2I28_05035	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
C2I28_05040	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
C2I28_05045	ENOG4108ZP8	Acetolactate synthase small subunit
C2I28_05050	ENOG4105C7K	acetolactate synthase
C2I28_05060	ENOG4105M59	Phosphodiesterase, mj0936 family
C2I28_05075	ENOG4108XJQ	germination protein
C2I28_05080	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
C2I28_05085	ENOG41067TZ	transcriptional regulator, MarR family
C2I28_05090	ENOG4108QCI	YvbH-like oligomerisation region
C2I28_05095	ENOG4105CJ3	phosphate transporter
C2I28_05100	ENOG4107GRR	phosphate transport regulator
C2I28_05105	ENOG4107RVG	penicillin-binding protein
C2I28_05115	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
C2I28_05120	ENOG4108UZX	fmn reductase
C2I28_05125	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
C2I28_05130	ENOG4108J8Z	aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein
C2I28_05135	ENOG4105D7T	ABC transporter
C2I28_05140	ENOG4107S91	Sodium hydrogen exchanger
C2I28_05145	ENOG4105NCW	Trka-c domain protein
C2I28_05155	ENOG4105PFC	Transcriptional regulator
C2I28_05165	ENOG4105E33	succinate dehydrogenase
C2I28_05175	ENOG4108NU2	Succinate dehydrogenase cytochrome b558 subunit
C2I28_05185	ENOG4105CFH	Aspartokinase
C2I28_05195	ENOG4105K63	Thioredoxin
C2I28_05205	ENOG4105C10	Electron transfer flavoprotein
C2I28_05210	ENOG4105BZJ	Electron transfer flavoprotein
C2I28_05215	ENOG41060WC	Enoyl-CoA hydratase
C2I28_05220	ENOG4107Z3H	Transcriptional regulator, TetR family
C2I28_05225	ENOG4105CEY	Amp-dependent synthetase and ligase
C2I28_05240	ENOG4105C98	muts2 protein
C2I28_05245	ENOG4105DCG	PHP domain protein
C2I28_05255	ENOG410687F	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
C2I28_05260	ENOG4107FSS	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
C2I28_05265	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
C2I28_05270	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
C2I28_05275	ENOG4108RWN	rrna methyltransferase
C2I28_05280	ENOG41067MF	small acid-soluble spore protein
C2I28_05285	ENOG4105CN9	Peptidase m42 family protein
C2I28_05305	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
C2I28_05310	ENOG4105VJV	50s ribosomal protein L35
C2I28_05315	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
C2I28_05320	ENOG4105C22	threonyL-tRNA synthetase
C2I28_05325	ENOG4108TDW	sporulation protein YtxC
C2I28_05340	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
C2I28_05350	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
C2I28_05355	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
C2I28_05370	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
C2I28_05375	ENOG4105C2M	dna polymerase I
C2I28_05380	ENOG4105BZU	Histidine kinase
C2I28_05385	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
C2I28_05395	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
C2I28_05400	ENOG4108HMX	isocitrate dehydrogenase (NADP)
C2I28_05405	ENOG4105BZN	citrate synthase
C2I28_05410	ENOG4107CWS	Protein of unknown function (DUF441)
C2I28_05415	ENOG4108REF	Sporulation integral membrane protein ytvi
C2I28_05420	ENOG4105FS0	cytoplasmic membrane protein
C2I28_05425	ENOG4105CA9	Pyruvate kinase
C2I28_05430	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
C2I28_05435	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
C2I28_05440	ENOG4107YCY	Transcriptional regulator
C2I28_05445	ENOG4105C6K	Malic enzyme
C2I28_05450	ENOG4105C0B	DNA polymerase III (alpha subunit)
C2I28_05455	ENOG4105VV2	
C2I28_05465	ENOG4105SFS	phosphoesterase RecJ domain protein
C2I28_05485	ENOG4105E8R	UPF0173 metal-dependent hydrolase
C2I28_05495	ENOG4105CH7	arginosuccinase
C2I28_05500	ENOG4105CDH	Citrulline--aspartate ligase
C2I28_05515	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
C2I28_05525	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
C2I28_05530	ENOG4105KBJ	sporulation protein ytfj
C2I28_05540	ENOG4105VK3	rdd domain containing protein
C2I28_05545	ENOG4105D07	Signal peptide peptidase, SppA
C2I28_05550	ENOG4108KKH	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
C2I28_05555	ENOG4105EFZ	amidohydrolase
C2I28_05565	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
C2I28_05580	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
C2I28_05585	ENOG4108W76	histidinol phosphate phosphatase hisj family
C2I28_05590	ENOG4105U5Y	Transcriptional regulator
C2I28_05600	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
C2I28_05605	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
C2I28_05615	ENOG4105F1V	Acetoin utilization protein
C2I28_05620	ENOG4105W87	Cbs domain
C2I28_05625	ENOG4105DGU	Histone deacetylase
C2I28_05630	ENOG4106VK6	Flagellar motor protein
C2I28_05635	ENOG4105E14	MotA TolQ exbB proton channel
C2I28_05640	ENOG4105ETE	Transcriptional regulator (LacI family
C2I28_05645	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
C2I28_05670	ENOG4105DFU	Cell wall formation (By similarity)
C2I28_05685	ENOG4108VDD	TRNA binding domain protein
C2I28_05690	ENOG4108NKM	UPF0354 protein
C2I28_05700	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
C2I28_05715	ENOG4105C8F	Beta-lactamase domain protein
C2I28_05720	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
C2I28_05730	ENOG4108V15	phosphotransferase enzyme family
C2I28_05735	ENOG4108IUM	Glycogen debranching enzyme
C2I28_05745	ENOG4107F58	2'-5' rna ligase
C2I28_05750	ENOG4105C6T	cysteine synthase
C2I28_05760	ENOG4107QSE	Dipeptidase
C2I28_05765	ENOG4105YW5	deoR family transcriptional regulator
C2I28_05780	ENOG4105CBX	hi0933 family
C2I28_05790	ENOG41085GJ	domain protein
C2I28_05795	ENOG4105C8T	Leucyl-tRNA synthetase
C2I28_05800	ENOG4105CY2	Citrate transporter
C2I28_05805	ENOG410605W	Major Facilitator
C2I28_05820	ENOG4105N5T	Radical SAM Protein
C2I28_05835	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
C2I28_05840	ENOG4108Z0R	Transferase
C2I28_05845	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
C2I28_05850	ENOG4105BZF	Glycosyl transferase (Group 1
C2I28_05855	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
C2I28_05860	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
C2I28_05875	ENOG4105D2X	ABC transporter substrate-binding protein
C2I28_05885	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
C2I28_05905	ENOG4108RMU	ferritin dps family protein
C2I28_05910	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
C2I28_05915	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
C2I28_05920	ENOG4108V2W	Carbonate dehydratase
C2I28_05925	ENOG4105CKI	cobalamin synthesis protein
C2I28_05935	ENOG4105NRA	50s ribosomal protein l31 type b
C2I28_05950	ENOG4105NQC	Flavodoxin
C2I28_05975	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C2I28_05980	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C2I28_05985	ENOG4105DTQ	mandelate racemase muconate lactonizing
C2I28_05990	ENOG4105CEY	Amp-dependent synthetase and ligase
C2I28_05995	ENOG4108IPT	Naphthoate synthase
C2I28_06000	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
C2I28_06005	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
C2I28_06010	ENOG4105E4F	Isochorismate synthase
C2I28_06030	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
C2I28_06040	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
C2I28_06170	ENOG4105CEY	Amp-dependent synthetase and ligase
C2I28_06175	ENOG4105KT7	mgtC SapB transporter
C2I28_06180	ENOG4108Z73	Siroheme synthase
C2I28_06185	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
C2I28_06190	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
C2I28_06195	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
C2I28_06225	ENOG4107PBV	potassium channel
C2I28_06235	ENOG4107QYV	phosphohexose isomerase
C2I28_06245	ENOG4105D65	subunit l
C2I28_06250	ENOG4105HC0	Na H antiporter
C2I28_06255	ENOG4108ZE9	Monovalent cation H antiporter subunit C
C2I28_06260	ENOG4108JPZ	Monovalent cation H antiporter subunit D
C2I28_06265	ENOG4105SC1	monovalent cation H antiporter subunit E
C2I28_06275	ENOG4105KJM	monovalent cation h antiporter subunit g
C2I28_06280	ENOG4107QW4	alcohol dehydrogenase
C2I28_06285	ENOG4105WG9	Conserved Protein
C2I28_06295	ENOG4105CHM	Aminotransferase
C2I28_06300	ENOG4108ZB6	transcriptional regulator AsnC family
C2I28_06305	ENOG4108MUZ	hydrolase
C2I28_06310	ENOG4105C87	Aminotransferase class I and II
C2I28_06315	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
C2I28_06325	ENOG4105Y38	Kinase-associated protein B
C2I28_06335	ENOG4105KA0	thioesterase Superfamily protein
C2I28_06360	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
C2I28_06370	ENOG41069ER	domain protein
C2I28_06380	ENOG4105CEP	NADH dehydrogenase
C2I28_06395	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
C2I28_06405	ENOG4105ZKE	UPF0349 protein
C2I28_06420	ENOG41083MR	nifu domain-containing protein
C2I28_06425	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
C2I28_06430	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
C2I28_06435	ENOG4105D6E	homoserine dehydrogenase
C2I28_06440	ENOG4105C5I	Dehydrogenase
C2I28_06450	ENOG4108W5N	phosphatidylglycerophosphatase a
C2I28_06455	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
C2I28_06470	ENOG4105MMD	transcriptional regulator
C2I28_06475	ENOG4106EGE	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
C2I28_06480	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
C2I28_06485	ENOG4105FAA	peptidase M23
C2I28_06495	ENOG4105C8J	)-transporter
C2I28_06500	ENOG4108YTE	sporulation protein YunB
C2I28_06505	ENOG4105KZD	Domain of unknown function (DUF1805)
C2I28_06510	ENOG4105I3N	Conserved Protein
C2I28_06515	ENOG4105DIW	FeS assembly protein SUFB
C2I28_06520	ENOG4108UNV	SUF system FeS assembly protein, NifU family
C2I28_06525	ENOG4105C9B	Cysteine desulfurase
C2I28_06530	ENOG4105JRK	feS assembly protein SufD
C2I28_06535	ENOG4105C3K	feS assembly ATPase SufC
C2I28_06545	ENOG4105D01	(LipO)protein
C2I28_06550	ENOG4108UMI	ABC transporter, permease
C2I28_06555	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
C2I28_06575	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
C2I28_06580	ENOG41080E8	Transcriptional regulator, Spx MgsR family
C2I28_06585	ENOG4105C1G	acyl-Coa dehydrogenase
C2I28_06590	ENOG4105CHU	acetyl-coa acetyltransferase
C2I28_06620	ENOG4105E0A	ABC, transporter
C2I28_06625	ENOG4108IHU	transport system permease protein
C2I28_06630	ENOG4105DQ5	transport system permease protein
C2I28_06635	ENOG4108MES	Periplasmic binding protein
C2I28_06650	ENOG41067SE	Tetr family transcriptional regulator
C2I28_06660	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
C2I28_06665	ENOG41079KZ	Major Facilitator Superfamily
C2I28_06670	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
C2I28_06675	ENOG4105CMU	LysR family (Transcriptional regulator
C2I28_06690	ENOG41062D9	Histidine kinase
C2I28_06695	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C2I28_06705	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
C2I28_06710	ENOG4105FS7	Transcriptional regulator
C2I28_06715	ENOG4108TVJ	Nitroreductase
C2I28_06720	ENOG41067WU	Molybdopterin converting factor (Subunit 1)
C2I28_06725	ENOG4108ZAF	Molybdopterin
C2I28_06730	ENOG4108129	molybdopterin-guanine dinucleotide biosynthesis protein
C2I28_06735	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
C2I28_06740	ENOG4105D06	uba thif-type nad fad binding protein
C2I28_06745	ENOG41082CS	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
C2I28_06755	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
C2I28_06760	ENOG4108ZSU	Uncharacterized conserved protein (DUF2294)
C2I28_06765	ENOG4108JB9	formate dehydrogenase
C2I28_06775	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
C2I28_06780	ENOG4105E0C	molybdate abc transporter
C2I28_06790	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
C2I28_06795	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
C2I28_06805	ENOG4105XZU	Preprotein translocase, subunit SecG
C2I28_06845	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C2I28_06860	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
C2I28_06865	ENOG4105KRI	phosphocarrier protein (HPr
C2I28_06875	ENOG4105CHW	UPF0052 protein
C2I28_06880	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
C2I28_06885	ENOG4108Z4K	mutator MutT protein
C2I28_06890	ENOG4105C3M	thioredoxin reductase
C2I28_06900	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
C2I28_06905	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
C2I28_06910	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
C2I28_06915	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
C2I28_06920	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
C2I28_06925	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
C2I28_06930	ENOG4107RN8	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
C2I28_06935	ENOG4108IQ6	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
C2I28_06940	ENOG4108S4C	acetyltransferase
C2I28_06945	ENOG4107XGZ	Hydrolase
C2I28_06950	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
C2I28_06955	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
C2I28_06960	ENOG41086DT	Membrane protein of unknown function
C2I28_06965	ENOG41067S9	phage shock protein C, PspC
C2I28_06970	ENOG4108PY7	
C2I28_06980	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
C2I28_06985	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
C2I28_06990	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C2I28_07010	ENOG4105CN1	protease
C2I28_07015	ENOG4105DR5	peptidase
C2I28_07020	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
C2I28_07025	ENOG4105CAK	Cell division ATP-binding protein ftsE
C2I28_07030	ENOG4108WS4	fmn reductase
C2I28_07040	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
C2I28_07045	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
C2I28_07050	ENOG4105DGI	Alkaline phosphatase
C2I28_07060	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
C2I28_07070	ENOG4105MS2	ribosomal subunit Interface protein
C2I28_07080	ENOG4105MQ3	flagellar protein FliS
C2I28_07085	ENOG4107RT6	flagellar hook-associated
C2I28_07095	ENOG4105C85	amino acid
C2I28_07105	ENOG4105C26	Dehydrogenase
C2I28_07110	ENOG4108JB8	alcohol dehydrogenase
C2I28_07115	ENOG4105TRT	Transcriptional regulator
C2I28_07120	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
C2I28_07125	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
C2I28_07130	ENOG4105DTJ	flagellar hook-associated protein
C2I28_07135	ENOG4105E1Q	flagellar hook-associated protein
C2I28_07155	ENOG41081UC	Inherit from COG: Competence protein
C2I28_07170	ENOG4105XVJ	Protein of unknown function (DUF327)
C2I28_07180	ENOG4105WH1	Two component transcriptional regulator luxr family
C2I28_07185	ENOG4105BZU	Histidine kinase
C2I28_07190	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
C2I28_07195	ENOG4108KGH	TRANSCRIPTIONal
C2I28_07200	ENOG4105ESV	Glycosyl transferase, family 4
C2I28_07210	ENOG4105DZ6	Band 7 protein
C2I28_07225	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
C2I28_07235	ENOG4105C0D	helicase
C2I28_07245	ENOG4105Z8H	single-stranded DNA-binding protein
C2I28_07265	ENOG4105CGA	flagellar basal-body rod protein FlgG
C2I28_07275	ENOG4105DFF	Rod shape-determining protein mreb
C2I28_07280	ENOG4105MT0	Sporulation transcriptional regulator spoiiid
C2I28_07285	ENOG4105FRN	stage II sporulation protein
C2I28_07305	ENOG4106778	Protein of unknown function (DUF1146)
C2I28_07310	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
C2I28_07315	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
C2I28_07320	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
C2I28_07325	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
C2I28_07330	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C2I28_07335	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
C2I28_07340	ENOG4105WS6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C2I28_07345	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
C2I28_07350	ENOG41062M3	atp synthase
C2I28_07360	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
C2I28_07365	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
C2I28_07370	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
C2I28_07385	ENOG4108YZG	isomerase
C2I28_07400	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
C2I28_07410	ENOG4108ZXQ	stage ii sporulation protein r
C2I28_07415	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
C2I28_07420	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
C2I28_07430	ENOG4105VFB	Binds the 23S rRNA (By similarity)
C2I28_07435	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
C2I28_07440	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
C2I28_07445	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
C2I28_07450	ENOG4105D2N	Aldolase
C2I28_07455	ENOG410812K	response regulator receiver protein
C2I28_07465	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
C2I28_07475	ENOG4105D5P	Methylmalonyl-coA mutase
C2I28_07485	ENOG4105C1G	acyl-Coa dehydrogenase
C2I28_07490	ENOG4105C1G	acyl-Coa dehydrogenase
C2I28_07495	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C2I28_07505	ENOG4105DF6	Fe-S oxidoreductase
C2I28_07520	ENOG4105C75	arginyL-tRNA synthetase
C2I28_07525	ENOG410684U	Domain of unknown function (DUF1934)
C2I28_07530	ENOG4105CYW	agmatinase
C2I28_07535	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
C2I28_07540	ENOG4105BZ4	penicillin-binding protein
C2I28_07545	ENOG4108XFG	YwhD family
C2I28_07550	ENOG4108Z4T	Peptidase M50
C2I28_07555	ENOG41069HH	4-oxalocrotonate tautomerase
C2I28_07565	ENOG4105DCI	Phosphohydrolase
C2I28_07575	ENOG4108VCI	transcription factor, rsfa family
C2I28_07585	ENOG4108IJ2	phosphate acetyltransferase
C2I28_07590	ENOG4107JTW	chlorite dismutase
C2I28_07595	ENOG4108VKI	Cell wall hydrolase
C2I28_07615	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
C2I28_07625	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
C2I28_07630	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
C2I28_07635	ENOG4108K8K	Transcriptional regulator
C2I28_07640	ENOG4105DCF	alanine dehydrogenase
C2I28_07650	ENOG4105DWF	phosphomethylpyrimidine kinase
C2I28_07655	ENOG410667J	hydrolase
C2I28_07660	ENOG4107URF	beta-phospho-glucomutase
C2I28_07665	ENOG4105CI1	PTS System
C2I28_07675	ENOG4105CPK	Glycosyl transferase (Group 1
C2I28_07680	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
C2I28_07690	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
C2I28_07700	ENOG4105CJR	Integral membrane protein (MviN
C2I28_07715	ENOG4108JJ8	(ABC) transporter
C2I28_07720	ENOG4108JJ9	ABC, transporter
C2I28_07725	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
C2I28_07730	ENOG4105C4M	(Ubiquinol oxidase) subunit I
C2I28_07735	ENOG4107XM3	UPF0442 protein
C2I28_07740	ENOG4105DWK	Membrane
C2I28_07745	ENOG4105ETE	Transcriptional regulator (LacI family
C2I28_07790	ENOG4107QPK	)-transporter
C2I28_07795	ENOG4105DR4	Methyltransferase
C2I28_07805	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C2I28_07810	ENOG4105BZU	Histidine kinase
C2I28_07825	ENOG4105M6F	mutator MutT protein
C2I28_07840	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
C2I28_07850	ENOG4105C0H	protease
C2I28_07855	ENOG4105Q2H	domain protein
C2I28_07870	ENOG4105BZU	Histidine kinase
C2I28_07875	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C2I28_07900	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
C2I28_07905	ENOG4105CDU	Replicative dna helicase
C2I28_07915	ENOG4105BZR	domain protein
C2I28_07925	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
C2I28_07930	ENOG4108UUM	single-stranded DNA-binding protein
C2I28_07940	ENOG4105C3G	gtp-binding protein
C2I28_07945	ENOG4105VDK	protein, conserved in bacteria
C2I28_07950	ENOG4105D8X	mechanosensitive ion channel
C2I28_07960	ENOG4108ZDA	Sporulation protein YyaC
C2I28_07965	ENOG4105FA0	parb-like partition protein
C2I28_07970	ENOG4107QJE	Chromosome Partitioning Protein
C2I28_07975	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
C2I28_07985	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
C2I28_07990	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
C2I28_08000	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
C2I28_08005	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
C2I28_08010	ENOG4105VG0	50S ribosomal protein l34
C2I28_08015	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
C2I28_08020	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
C2I28_08025	ENOG410848D	S4 domain protein YaaA
C2I28_08035	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C2I28_08040	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C2I28_08075	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
C2I28_08085	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
C2I28_08090	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
C2I28_08105	ENOG4105ZMH	deoxynucleoside kinase
C2I28_08115	ENOG4105VRS	hydrolase family 18
C2I28_08120	ENOG4105GTG	Isochorismatase
C2I28_08125	ENOG4108Z6B	deaminase
C2I28_08135	ENOG4105C6E	dna polymerase iii
C2I28_08140	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
C2I28_08145	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
C2I28_08155	ENOG41067KS	pro-sigma K processing
C2I28_08250	ENOG4105CXN	decarboxylase
C2I28_08255	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
C2I28_08260	ENOG4105X0R	protein from nitrogen regulatory protein P-II
C2I28_08265	ENOG4105FA2	dna polymerase iii
C2I28_08270	ENOG4105MA4	psp1 domain protein
C2I28_08275	ENOG4105QD5	Involved in initiation control of chromosome replication (By similarity)
C2I28_08280	ENOG41060K3	Methyltransferase
C2I28_08285	ENOG4105VC4	domain protein
C2I28_08290	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
C2I28_08295	ENOG4105KRN	Transcriptional regulator, abrb family
C2I28_08300	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
C2I28_08305	ENOG4105F8V	Hydrolase, tatD family
C2I28_08310	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
C2I28_08315	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
C2I28_08320	ENOG4105XFA	sporulation peptidase YabG
C2I28_08325	ENOG4105W42	Veg protein
C2I28_08340	ENOG4105DFT	pur operon repressor
C2I28_08345	ENOG4105KME	endoribonuclease L-psp
C2I28_08350	ENOG4105K4W	Could be involved in septation (By similarity)
C2I28_08355	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
C2I28_08360	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
C2I28_08365	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
C2I28_08370	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
C2I28_08380	ENOG4108JA2	transcriptioN-repair coupling factor
C2I28_08385	ENOG4108M14	stage v sporulation protein t
C2I28_08395	ENOG4108IY2	MazG family
C2I28_08400	ENOG41082I2	s4 domain protein
C2I28_08405	ENOG4105VYY	sporulation protein yabp
C2I28_08420	ENOG41060GV	RNA binding s1 domain protein
C2I28_08435	ENOG4105G3A	stage ii sporulation protein e
C2I28_08450	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
C2I28_08455	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
C2I28_08460	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
C2I28_08465	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
C2I28_08470	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
C2I28_08475	ENOG4105C6T	cysteine synthase
C2I28_08480	ENOG4105CRQ	synthase (Component I)
C2I28_08485	ENOG4105DDQ	anthranilate synthase
C2I28_08490	ENOG41082R7	4-amino-4-deoxychorismate lyase EC 4.1.3.38
C2I28_08495	ENOG4105KRF	dihydroneopterin aldolase
C2I28_08500	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C2I28_08505	ENOG4105CRK	lysyL-tRNA synthetase
C2I28_08530	ENOG4108Z0C	Uvrb UvrC protein
C2I28_08535	ENOG41066A3	ATP guanido phosphotransferase
C2I28_08545	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
C2I28_08550	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
C2I28_08555	ENOG4105CTP	PilT protein domain protein
C2I28_08560	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
C2I28_08565	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
C2I28_08570	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
C2I28_08575	ENOG4105D7W	serine acetyltransferase
C2I28_08580	ENOG4105C8N	cysteinyl-tRNA synthetase
C2I28_08590	ENOG4105C2N	RNA methyltransferase TrmH family group 3
C2I28_08595	ENOG4105M0M	Tetracycline resistance protein
C2I28_08600	ENOG4105QIV	RNA polymerase
C2I28_08605	ENOG41087NY	50S ribosomal protein L33
C2I28_08615	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
C2I28_08625	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
C2I28_08630	ENOG4108VZM	50s ribosomal protein L10
C2I28_08635	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
C2I28_08640	ENOG4107Y49	methyltransferase
C2I28_08645	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C2I28_08650	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C2I28_08655	ENOG4105XPM	ribosomal protein
C2I28_08660	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
C2I28_08665	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
C2I28_08675	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
C2I28_08685	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
C2I28_08690	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
C2I28_08695	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
C2I28_08700	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C2I28_08705	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
C2I28_08710	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
C2I28_08715	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
C2I28_08720	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
C2I28_08725	ENOG41082SA	50s ribosomal protein l29
C2I28_08730	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
C2I28_08735	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
C2I28_08750	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
C2I28_08755	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
C2I28_08760	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
C2I28_08770	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
C2I28_08775	ENOG4105VPB	50S ribosomal protein L30
C2I28_08780	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
C2I28_08785	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
C2I28_08790	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
C2I28_08795	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
C2I28_08800	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
C2I28_08810	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C2I28_08820	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C2I28_08825	ENOG4108ZT0	50S ribosomal protein l17
C2I28_08830	ENOG4108JJB	ABC transporter
C2I28_08835	ENOG4108JJB	ABC transporter
C2I28_08840	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
C2I28_08845	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
C2I28_08850	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
C2I28_08870	ENOG4105D1F	ATP-binding protein
C2I28_08875	ENOG4108KSA	LysR family transcriptional regulator
C2I28_08890	ENOG4108NMV	polysaccharide deacetylase
C2I28_08970	ENOG4105EMN	RNA polymerase sigma factor
C2I28_08980	ENOG4105C8B	TIGR00159 family
C2I28_08990	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
C2I28_08995	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
C2I28_09010	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
C2I28_09015	ENOG4105CTS	PTS system mannitol-specific
C2I28_09020	ENOG4105ETD	TRANSCRIPTIONal
C2I28_09025	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
C2I28_09035	ENOG4108VZI	ErfK ybiS ycfS ynhG family protein
C2I28_09040	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
C2I28_09045	ENOG4107T7U	Sulfatase
C2I28_09060	ENOG4105F38	ABC transporter, permease
C2I28_09065	ENOG4105D38	putrescine abc transporter
C2I28_09070	ENOG4107RUE	extracellular solute-binding protein family 1
C2I28_09085	ENOG4105US7	Histidine kinase
C2I28_09095	ENOG41081YB	ApbE family
C2I28_09100	ENOG4105I7V	membrAne
C2I28_09105	ENOG4105CPF	Cell wall formation (By similarity)
C2I28_09110	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
C2I28_09115	ENOG4105C1J	atp-dependent rna helicase
C2I28_09130	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
C2I28_09135	ENOG4108SGW	outer membrane lipoprotein-sorting protein-like protein
C2I28_09140	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
C2I28_09150	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
C2I28_09155	ENOG4107MMM	Anti-sigma-factor antagonist
C2I28_09160	ENOG4105FUA	antagonist
C2I28_09165	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
C2I28_09170	ENOG4107SGM	protein serine threonine phosphatase
C2I28_09175	ENOG4105WN5	stage II sporulation protein
C2I28_09190	ENOG41064BQ	Phosphatase
C2I28_09290	ENOG4105K8N	protein family UPF0079, ATPase
C2I28_09295	ENOG41072GX	Peptidase M22 Glycoprotease
C2I28_09300	ENOG410801F	ribosomal-protein-alanine acetyltransferase
C2I28_09305	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
C2I28_09310	ENOG4105C5H	ABC transporter
C2I28_09315	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
C2I28_09320	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
C2I28_09325	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
C2I28_09335	ENOG4108TYN	CAAX amino terminal protease family protein
C2I28_09340	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
C2I28_09345	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
C2I28_09350	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C2I28_09365	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C2I28_09370	ENOG4105C7N	Xanthine uracil vitamin C permease
C2I28_09425	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
C2I28_09430	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
C2I28_09435	ENOG4105C83	adenylosuccinate lyase
C2I28_09440	ENOG4105C8V	SAICAR synthetase
C2I28_09445	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
C2I28_09450	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
C2I28_09455	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
C2I28_09465	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
C2I28_09470	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
C2I28_09475	ENOG4105DC1	bifunctional purine biosynthesis protein purh
C2I28_09480	ENOG4105C12	Phosphoribosylglycinamide synthetase
C2I28_09495	ENOG4105KGF	protein, YerC YecD
C2I28_09500	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
C2I28_09510	ENOG4105C4R	Atp-dependent dna helicase
C2I28_09515	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
C2I28_09530	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
C2I28_09535	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
C2I28_09540	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
C2I28_09545	ENOG4105CBD	Diacylglycerol kinase
C2I28_09565	ENOG4107AYK	membrAne
C2I28_09580	ENOG4105DIH	basic membrane
C2I28_09585	ENOG4105BZU	Histidine kinase
C2I28_09590	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
C2I28_09595	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
C2I28_09600	ENOG4107QWG	2-Nitropropane dioxygenase
C2I28_09605	ENOG4108Z5V	transcriptional regulator, merr family
C2I28_09610	ENOG4105C2C	drug resistance transporter, Bcr CflA
C2I28_09625	ENOG4105CDA	abc transporter atp-binding protein
C2I28_09630	ENOG4105CT1	(ABC) transporter
C2I28_09635	ENOG4105EAD	ABC transporter
C2I28_09640	ENOG4105DRP	amino acid AbC transporter
C2I28_09650	ENOG4106BRA	Membrane
C2I28_09665	ENOG41062D9	Histidine kinase
C2I28_09670	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C2I28_09680	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
C2I28_09700	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
C2I28_09705	ENOG4108ZHJ	Organic hydroperoxide resistance protein
C2I28_09725	ENOG4107R7Y	intracellular protease Pfpi family
C2I28_09735	ENOG4106DF1	
C2I28_09745	ENOG4105BZG	amino acid carrier protein
C2I28_09765	ENOG4105D7N	magnesium and cobalt transport protein CorA
C2I28_09775	ENOG4108MRH	transcriptional regulatory protein
C2I28_09790	ENOG4105BZU	Histidine kinase
C2I28_09795	ENOG4105FDU	atp-dependent rna helicase
C2I28_09805	ENOG4108IBT	Inherit from COG: transposase
C2I28_09850	ENOG4108K8S	endonuclease I
C2I28_09860	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
C2I28_09875	ENOG4105C5H	ABC transporter
C2I28_09880	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
C2I28_09900	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
C2I28_09910	ENOG4108Z0Z	intracellular protease Pfpi family
C2I28_09915	ENOG4105K4I	Scp-like extracellular
C2I28_09920	ENOG4105CPN	adenine deaminase
C2I28_09930	ENOG4105KJF	protein tyrosine phosphatase
C2I28_09940	ENOG4107U9T	Pfam:Ribonuclease_BN
C2I28_09945	ENOG4105C59	p-type ATPase
C2I28_09955	ENOG4105KTU	Transcriptional regulator, arsr family
C2I28_09960	ENOG4105PGM	cation diffusion facilitator family transporter
C2I28_09965	ENOG4108ISG	Major Facilitator
C2I28_09970	ENOG4105NI3	Protein of unknown function (DUF3237)
C2I28_09975	ENOG4105PY6	Phenolic acid decarboxylase
C2I28_09985	ENOG410606W	general stress protein
C2I28_09990	ENOG4105UPD	Calcium Proton
C2I28_10020	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
C2I28_10030	ENOG4105C85	amino acid
C2I28_10035	ENOG4105BZU	Histidine kinase
C2I28_10055	ENOG4105ECP	epimerase
C2I28_10065	ENOG4108RZ4	Short-chain dehydrogenase reductase Sdr
C2I28_10075	ENOG4105XHU	Acid-soluble spore protein K
C2I28_10085	ENOG41067AE	Membrane-bound metal-dependent hydrolase
C2I28_10090	ENOG4105CEN	a g-specific adenine glycosylase
C2I28_10095	ENOG4106BXE	
C2I28_10100	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
C2I28_10115	ENOG4105EVI	UPF0374 protein
C2I28_10120	ENOG4105BZ1	(ABC) transporter
C2I28_10125	ENOG4107NBY	Membrane
C2I28_10130	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
C2I28_10135	ENOG4108IUW	ABC transporter
C2I28_10155	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C2I28_10160	ENOG4105G5W	regulator Fur family
C2I28_10165	ENOG4105TUA	UPF0295 protein
C2I28_10270	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C2I28_10315	ENOG41078D9	
C2I28_10335	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
C2I28_10345	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
C2I28_10350	ENOG4105CYN	Serine protein kinase
C2I28_10355	ENOG4106AKX	UPF0229 protein
C2I28_10365	ENOG41076HS	cation diffusion facilitator family transporter
C2I28_10380	ENOG4108Q5U	germination protein, ger(x)c family
C2I28_10395	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
C2I28_10405	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
C2I28_10415	ENOG4108REF	Sporulation integral membrane protein ytvi
C2I28_10420	ENOG4107T5V	SNARE associated Golgi
C2I28_10425	ENOG4105EU9	
C2I28_10430	ENOG4105CUB	amino acid
C2I28_10450	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
C2I28_10455	ENOG4108IJ9	(ABC) transporter
C2I28_10460	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
C2I28_10470	ENOG4105BZ7	extracellular solute-binding protein family 1
C2I28_10475	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
C2I28_10490	ENOG4105DTQ	mandelate racemase muconate lactonizing
C2I28_10535	ENOG41069ER	domain protein
C2I28_10540	ENOG4108VXD	carboxy-peptidase
C2I28_10555	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
C2I28_10560	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
C2I28_10575	ENOG4105YWU	small acid-soluble spore protein
C2I28_10585	ENOG4105ETE	Transcriptional regulator (LacI family
C2I28_10590	ENOG4105IE8	Alpha-ketoglutarate permease
C2I28_10595	ENOG4105CK5	oxidoreductase
C2I28_10620	ENOG4105ETE	Transcriptional regulator (LacI family
C2I28_10625	ENOG4105DH8	myo-inositol catabolism
C2I28_10635	ENOG4108JYZ	YitT family
C2I28_10670	ENOG4105FE9	pseudouridine synthase
C2I28_10680	ENOG41090U3	tautomerase
C2I28_10690	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
C2I28_10695	ENOG4105DEF	Extracellular solute-binding protein, family 5
C2I28_10715	ENOG4108RE7	deoxyribonuclease
C2I28_10720	ENOG4105FR1	rard protein
C2I28_10745	ENOG4105CB2	alcohol dehydrogenase
C2I28_10750	ENOG4105DAA	L-lactate
C2I28_10755	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
C2I28_10765	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
C2I28_10770	ENOG4108YBP	pseudouridine synthase
C2I28_10785	ENOG4105CK5	oxidoreductase
C2I28_10790	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
C2I28_10795	ENOG4108PXI	ErfK YbiS YcfS YnhG
C2I28_10800	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
C2I28_10805	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
C2I28_10815	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
C2I28_10820	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
C2I28_10840	ENOG4105ED1	spovr family
C2I28_10850	ENOG4108Z40	Transcriptional regulator
C2I28_10865	ENOG4105CDA	abc transporter atp-binding protein
C2I28_10870	ENOG4105DRP	amino acid AbC transporter
C2I28_10895	ENOG4108VEU	Thiamine monophosphate synthase
C2I28_10900	ENOG41080HI	glycine oxidase
C2I28_10915	ENOG4105D06	uba thif-type nad fad binding protein
C2I28_10920	ENOG4105DWF	phosphomethylpyrimidine kinase
C2I28_10945	ENOG4105YWU	small acid-soluble spore protein
C2I28_10975	ENOG410839P	
C2I28_10990	ENOG4105WZB	UPF0342 protein
C2I28_11000	ENOG4105D4P	Coproporphyrinogen iii oxidase
C2I28_11005	ENOG4105CEY	Amp-dependent synthetase and ligase
C2I28_11010	ENOG4105CGU	Enoyl-CoA hydratase
C2I28_11015	ENOG4105K70	DNA-binding protein
C2I28_11025	ENOG4108IUX	(ABC) transporter
C2I28_11030	ENOG4105RHA	ABC transporter, permease
C2I28_11040	ENOG4105EQI	Metal Dependent Phosphohydrolase
C2I28_11050	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
C2I28_11075	ENOG41088ZC	Negative regulator of protease production and sporulation (By similarity)
C2I28_11085	ENOG4105NBU	tryptophan transport protein
C2I28_11090	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
C2I28_11095	ENOG4105U3E	Transcriptional regulator
C2I28_11100	ENOG4107YB6	acetyltransferase, (GNAT) family
C2I28_11105	ENOG4105EXC	Acyl-transferase
C2I28_11110	ENOG4105K59	histidine triad (HIT) protein
C2I28_11135	ENOG410841Q	phosphoesterase PA-phosphatase related protein
C2I28_11145	ENOG4105Q24	Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation
C2I28_11150	ENOG4105BZ4	penicillin-binding protein
C2I28_11155	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
C2I28_11160	ENOG4107TTW	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
C2I28_11165	ENOG4105C1Q	protoporphyrinogen oxidase
C2I28_11175	ENOG4107RF6	penicillin-binding protein
C2I28_11185	ENOG4105C2F	Histidine kinase
C2I28_11200	ENOG4108RQ5	Beta-lactamase domain-containing protein
C2I28_11205	ENOG4105DF9	Lipoate-protein, ligase
C2I28_11210	ENOG4105CEY	Amp-dependent synthetase and ligase
C2I28_11215	ENOG4105E39	Enoyl-CoA hydratase
C2I28_11330	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
C2I28_11345	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
C2I28_11355	ENOG4105CHR	reductase
C2I28_11365	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
C2I28_11375	ENOG4105EYH	Exonuclease
C2I28_11420	ENOG4105YHS	UPF0344 protein
C2I28_11430	ENOG4105CAQ	asparagine synthetase
C2I28_11445	ENOG4105FE1	phytoene synthase
C2I28_11450	ENOG4108YZA	Nitrogen regulatory protein pii
C2I28_11460	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
C2I28_11465	ENOG4105FKQ	transcriptional regulator
C2I28_11470	ENOG4105C26	Dehydrogenase
C2I28_11475	ENOG4105C8Y	Acetylornithine aminotransferase
C2I28_11490	ENOG4108JUB	Transcriptional regulator
C2I28_11495	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
C2I28_11500	ENOG4108VPT	UPF0234 protein
C2I28_11505	ENOG4105QNR	S1 RNA binding domain protein
C2I28_11515	ENOG4105EPR	degv family
C2I28_11520	ENOG4107AYK	membrAne
C2I28_11530	ENOG4108KP7	hydrolase
C2I28_11535	ENOG4105VG1	fes assembly suf system protein
C2I28_11540	ENOG4107V6Q	Cyclic nucleotide-binding domain
C2I28_11545	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
C2I28_11550	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
C2I28_11555	ENOG4105CAS	nag kinase
C2I28_11575	ENOG4105DBV	ornithine carbamoyltransferase
C2I28_11590	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C2I28_11605	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
C2I28_11610	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
C2I28_11615	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
C2I28_11645	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
C2I28_11650	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
C2I28_11660	ENOG4105C3U	ABC transporter
C2I28_11665	ENOG4108JQ7	(ABC) transporter
C2I28_11685	ENOG4108KU1	UPF0736 protein
C2I28_11690	ENOG4105C31	Tryptophanyl-tRNA synthetase
C2I28_11700	ENOG4108J59	Extracellular solute-binding protein, family 5
C2I28_11705	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C2I28_11710	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C2I28_11720	ENOG4108JQ7	(ABC) transporter
C2I28_11730	ENOG4105C85	amino acid
C2I28_11735	ENOG4105D5Q	Arginine ornithine antiporter
C2I28_11740	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
C2I28_11745	ENOG4107RSM	transcriptional regulator
C2I28_11760	ENOG4108ZCF	integral membrane protein
C2I28_11770	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
C2I28_11780	ENOG4105DPN	Oligoendopeptidase f
C2I28_11790	ENOG4105T58	Dithiol-disulfide isomerase
C2I28_11795	ENOG4108Z18	K06886 hemoglobin
C2I28_11800	ENOG4105E4C	Lytic transglycosylase catalytic
C2I28_11805	ENOG4105MIX	Adenylate cyclase
C2I28_11820	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
C2I28_11825	ENOG4105EMS	pseudouridine synthase
C2I28_11835	ENOG4105CJW	magnesium transporter
C2I28_11890	ENOG4105ENA	helicase
C2I28_11900	ENOG4105H67	Protein of unknown function (DUF421)
C2I28_11910	ENOG4108ZMI	UPF0477 protein
C2I28_11930	ENOG4108W5N	phosphatidylglycerophosphatase a
C2I28_11940	ENOG4106KNT	transcriptional regulator
C2I28_11950	ENOG4105CMG	Carbohydrate kinase
C2I28_11955	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
C2I28_11960	ENOG4105C6Z	Gluconate
C2I28_11980	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
C2I28_12000	ENOG4105C1J	atp-dependent rna helicase
C2I28_12005	ENOG4106N3A	copper homeostasis protein cutc
C2I28_12010	ENOG4105C85	amino acid
C2I28_12020	ENOG4108W8B	Beta-lactamase domain protein
C2I28_12030	ENOG4105EMD	TRANSCRIPTIONal
C2I28_12035	ENOG4105VZJ	PTS System
C2I28_12040	ENOG4105CK1	PTS System
C2I28_12045	ENOG4105VCP	PTS System
C2I28_12050	ENOG4105F8D	glycoside hydrolase family 4
C2I28_12055	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C2I28_12070	ENOG4108HRK	Histidine kinase
C2I28_12075	ENOG4105DY9	regulatoR
C2I28_12080	ENOG41083D3	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses (By similarity)
C2I28_12085	ENOG41067MG	lrgb family
C2I28_12100	ENOG4108IFG	nitrite reductase, (NAD(P)H)
C2I28_12105	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
C2I28_12115	ENOG4107FQX	Alpha-acetolactate decarboxylase
C2I28_12140	ENOG4105KVH	Transcriptional regulator
C2I28_12145	ENOG4105F27	Major Facilitator
C2I28_12150	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
C2I28_12155	ENOG4107EEY	synthase
C2I28_12170	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
C2I28_12195	ENOG4105CSV	Glutaminase
C2I28_12205	ENOG4105E1V	na solute symporter
C2I28_12215	ENOG4105Q95	Cupin 2, conserved barrel domain protein
C2I28_12220	ENOG4107QTZ	amino acid
C2I28_12230	ENOG4108S4H	thioesterase Superfamily protein
C2I28_12240	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
C2I28_12255	ENOG4105C4B	ABC transporter, permease
C2I28_12260	ENOG4108IXI	(ABC) transporter
C2I28_12275	ENOG4107X8C	Efflux transporter RND family MFP subunit
C2I28_12280	ENOG4105C19	ABC transporter
C2I28_12285	ENOG4107RBB	ABC transporter, permease
C2I28_12295	ENOG4105EEI	dihydropteroate synthase
C2I28_12315	ENOG4108IQI	permease
C2I28_12325	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
C2I28_12330	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
C2I28_12340	ENOG4108ZCF	integral membrane protein
C2I28_12345	ENOG4105CK2	sodium dicarboxylate symporter
C2I28_12350	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
C2I28_12355	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
C2I28_12360	ENOG4108MRH	transcriptional regulatory protein
C2I28_12365	ENOG4105CSC	Glucose uptake protein
C2I28_12370	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
C2I28_12390	ENOG4107D63	
C2I28_12395	ENOG4105VZ8	Transcriptional regulator
C2I28_12405	ENOG4105E0M	Sulfatase
C2I28_12420	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
C2I28_12425	ENOG4108J5H	Homocysteine s-methyltransferase
C2I28_12430	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
C2I28_12445	ENOG4105D4T	Citrate transporter
C2I28_12455	ENOG4108MRH	transcriptional regulatory protein
C2I28_12465	ENOG4108KAM	Transcriptional regulator
C2I28_12470	ENOG4108KK1	membrane protein AbrB duplication
C2I28_12475	ENOG41089UC	methyltransferase, type 11
C2I28_12480	ENOG4107SQ8	Glycine betaine
C2I28_12485	ENOG4108IJ7	Glycine betaine
C2I28_12500	ENOG4105C26	Dehydrogenase
C2I28_12505	ENOG4105C8Y	Acetylornithine aminotransferase
C2I28_12515	ENOG4105CUB	amino acid
C2I28_12520	ENOG4107YBY	Hydrolase
C2I28_12530	ENOG4107T8P	acyl-Coa dehydrogenase
C2I28_12535	ENOG4105FBW	Monooxygenase
C2I28_12540	ENOG4107T8P	acyl-Coa dehydrogenase
C2I28_12545	ENOG4108HUF	Transporter
C2I28_12550	ENOG4105DQ5	transport system permease protein
C2I28_12555	ENOG4108U1V	ABC transporter, permease
C2I28_12565	ENOG4108S0J	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity)
C2I28_12580	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C2I28_12605	ENOG4105ETU	transcriptional activator (TenA
C2I28_12615	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
C2I28_12630	ENOG41080HJ	6-phospho 3-hexuloisomerase
C2I28_12635	ENOG4108VA3	3-hexulose-6-phosphate synthase
C2I28_12640	ENOG4105KVH	Transcriptional regulator
C2I28_12675	ENOG4105ECB	domain protein
C2I28_12685	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C2I28_12690	ENOG4105KVH	Transcriptional regulator
C2I28_12700	ENOG4105BZ1	(ABC) transporter
C2I28_12705	ENOG4105BZ1	(ABC) transporter
C2I28_12725	ENOG4105MI2	
C2I28_12730	ENOG4107HP6	Transcriptional regulator
C2I28_12740	ENOG4108VHC	Short-chain dehydrogenase reductase Sdr
C2I28_12745	ENOG4105DG6	mannose-6-phosphate isomerase
C2I28_12750	ENOG4105C8I	hydrolase, family 38
C2I28_12755	ENOG4105DM4	PTS System
C2I28_12760	ENOG4108Q3X	Transcriptional regulator
C2I28_12765	ENOG41067TZ	transcriptional regulator, MarR family
C2I28_12770	ENOG4105CW7	secretion protein, HlyD family
C2I28_12775	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C2I28_12780	ENOG4105CS1	NAD(P)H quinone oxidoreductase
C2I28_12795	ENOG4105ETE	Transcriptional regulator (LacI family
C2I28_12800	ENOG4108RVA	ribokinase
C2I28_12805	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
C2I28_12810	ENOG4105C2J	ABC transporter
C2I28_12815	ENOG4105CNN	ABC, transporter
C2I28_12820	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
C2I28_12825	ENOG41069ER	domain protein
C2I28_12830	ENOG4107XC4	flavin reductase domain protein, FMN-binding
C2I28_12860	ENOG4105BZU	Histidine kinase
C2I28_12870	ENOG4107QJZ	Glycosyl transferase, family 2
C2I28_12880	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C2I28_12885	ENOG4105BZU	Histidine kinase
C2I28_12895	ENOG4106HB6	Alpha beta hydrolase
C2I28_12910	ENOG4108JPW	Aminotransferase
C2I28_12925	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
C2I28_12930	ENOG4105C7N	Xanthine uracil vitamin C permease
C2I28_12935	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
C2I28_12945	ENOG4105C5Y	PTS System
C2I28_12950	ENOG4105CG3	alpha amylase, catalytic region
C2I28_12955	ENOG4107414	GntR family transcriptional regulator
C2I28_12960	ENOG4105P4J	Allophanate hydrolase, subunit 1
C2I28_12970	ENOG4105E7W	lamb ycsf family protein
C2I28_12975	ENOG4105C5A	transporter
C2I28_12980	ENOG4108UT2	hemolysin iii
C2I28_12995	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
C2I28_13000	ENOG4106F5Q	Membrane
C2I28_13010	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
C2I28_13025	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
C2I28_13040	ENOG4105CUB	amino acid
C2I28_13045	ENOG4105DZC	cytosine deaminase
C2I28_13055	ENOG4105CJ1	ABC, transporter
C2I28_13060	ENOG4105VEQ	Cold shock protein
C2I28_13065	ENOG4108RYK	Nad-dependent epimerase dehydratase
C2I28_13070	ENOG4105EE0	oxidoreductase
C2I28_13075	ENOG4105D3R	alkyl hydroperoxide reductase
C2I28_13080	ENOG4107R19	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C2I28_13105	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
C2I28_13110	ENOG4105KPY	Small multidrug resistance protein
C2I28_13115	ENOG4105KPY	Small multidrug resistance protein
C2I28_13185	ENOG4105F32	YngK protein
C2I28_13190	ENOG4106KNT	transcriptional regulator
C2I28_13210	ENOG4105F8D	glycoside hydrolase family 4
C2I28_13220	ENOG4105VCP	PTS System
C2I28_13230	ENOG4105RD7	BadF BadG BcrA BcrD
C2I28_13235	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C2I28_13250	ENOG4105E66	phosphoriboisomerase A
C2I28_13265	ENOG4108VZI	ErfK ybiS ycfS ynhG family protein
C2I28_13275	ENOG4108WAV	Transcriptional regulator
C2I28_13285	ENOG4105CPC	Aldo Keto reductase
C2I28_13295	ENOG4108QG2	Membrane
C2I28_13305	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
C2I28_13315	ENOG4105CMR	udp-glucose 4-epimerase
C2I28_13365	ENOG4105BZU	Histidine kinase
C2I28_13370	ENOG4105BZU	Histidine kinase
C2I28_13375	ENOG4105KVH	Transcriptional regulator
C2I28_13380	ENOG4105CSC	Glucose uptake protein
C2I28_13385	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
C2I28_13390	ENOG4105C09	Bile acid
C2I28_13395	ENOG4106CAD	Protein of unknown function (DUF3311)
C2I28_13400	ENOG4105E1V	na solute symporter
C2I28_13450	ENOG4105CV8	reductase
C2I28_13470	ENOG4105DTQ	mandelate racemase muconate lactonizing
C2I28_13490	ENOG4108JPW	Aminotransferase
C2I28_13500	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C2I28_13515	ENOG41082BM	Transcriptional regulator, arsr family
C2I28_13550	ENOG4105BZU	Histidine kinase
C2I28_13555	ENOG4105EUJ	GTP cyclohydrolase i
C2I28_13560	ENOG4108JU3	Alkyl hydroperoxide reductase
C2I28_13570	ENOG4105BZU	Histidine kinase
C2I28_13580	ENOG4105I03	Flagellin
C2I28_13615	ENOG4107RVV	histidinol phosphate phosphatase, hisj family
C2I28_13625	ENOG4108IMY	Transcriptional regulator
C2I28_13645	ENOG4105JFG	SpoIID LytB domain protein
C2I28_13655	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
C2I28_13660	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
C2I28_13665	ENOG4105D3Q	Sugar transferase
C2I28_13690	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
C2I28_13695	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
C2I28_13700	ENOG4105C2X	Arabinose 5-phosphate isomerase
C2I28_13705	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
C2I28_13715	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
C2I28_13720	ENOG4105DG6	mannose-6-phosphate isomerase
C2I28_13730	ENOG4105HTX	biosynthesis protein
C2I28_13735	ENOG4107YJ4	chain length determinant protein
C2I28_13740	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
C2I28_13765	ENOG4107VDP	teichoic acid biosynthesis
C2I28_13775	ENOG4105EY8	ABC transporter
C2I28_13785	ENOG4108KGH	TRANSCRIPTIONal
C2I28_13795	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
C2I28_13810	ENOG4105CBC	glutamate synthase
C2I28_13820	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
C2I28_13830	ENOG4105C6Z	Gluconate
C2I28_13850	ENOG4108IFG	nitrite reductase, (NAD(P)H)
C2I28_13855	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
C2I28_13860	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
C2I28_13865	ENOG4108QTI	)-transporter
C2I28_13875	ENOG4105D7K	pfkb domain protein
C2I28_13895	ENOG4107QJQ	Mate efflux family protein
C2I28_13910	ENOG4108KGH	TRANSCRIPTIONal
C2I28_13920	ENOG4105D7N	magnesium and cobalt transport protein CorA
C2I28_13925	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
C2I28_13945	ENOG4108SU4	UPF0309 protein
C2I28_13950	ENOG4105FDP	GntR family transcriptional regulator
C2I28_13955	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
C2I28_13960	ENOG4105CE4	GlcNAc 6-P deacetylase
C2I28_13965	ENOG4105CI1	PTS System
C2I28_13970	ENOG4108UQV	Membrane
C2I28_14005	ENOG4105CJ1	ABC, transporter
C2I28_14010	ENOG4105C37	(CBS) domain
C2I28_14025	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
C2I28_14060	ENOG4105C8Q	Methyl-accepting chemotaxis
C2I28_14065	ENOG4108XSB	acetyltransferase, (GNAT) family
C2I28_14070	ENOG4105CH2	amidohydrolase
C2I28_14095	ENOG4105RHY	Pfam:UPF0157
C2I28_14100	ENOG4105DP8	Major facilitator superfamily MFS_1
C2I28_14110	ENOG4105C7N	Xanthine uracil vitamin C permease
C2I28_14120	ENOG4107Y7X	LytTR
C2I28_14125	ENOG4108IUW	ABC transporter
C2I28_14130	ENOG4108SDH	ABC, transporter
C2I28_14150	ENOG4105E0X	reductase
C2I28_14155	ENOG4108B31	Spore germination protein
C2I28_14170	ENOG4105G6Z	alkaline phosphatase
C2I28_14175	ENOG4105DY9	regulatoR
C2I28_14180	ENOG4105BZU	Histidine kinase
C2I28_14185	ENOG4107TS3	membrane protein, TerC
C2I28_14190	ENOG4108WZW	RNA polymerase sigma
C2I28_14195	ENOG410681C	small acid-soluble spore protein
C2I28_14215	ENOG4105CHR	reductase
C2I28_14235	ENOG4105JXH	GntR family transcriptional regulator
C2I28_14240	ENOG4105DAP	Nicotinate phosphoribosyltransferase
C2I28_14245	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
C2I28_14250	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
C2I28_14255	ENOG4107QR9	Iron-sulfur cluster binding protein
C2I28_14260	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
C2I28_14265	ENOG4105BZU	Histidine kinase
C2I28_14270	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
C2I28_14280	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
C2I28_14285	ENOG4105CT5	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity)
C2I28_14290	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
C2I28_14300	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
C2I28_14305	ENOG4105JAS	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity)
C2I28_14310	ENOG4107V49	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
C2I28_14315	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
C2I28_14325	ENOG4105C2J	ABC transporter
C2I28_14330	ENOG4105CNN	ABC, transporter
C2I28_14355	ENOG41090MY	MarR family Transcriptional regulator
C2I28_14365	ENOG4105BZU	Histidine kinase
C2I28_14380	ENOG4105DFD	Na H antiporter
C2I28_14395	ENOG4105E1K	spore germination protein
C2I28_14415	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
C2I28_14420	ENOG4107ZAE	6-carboxy-5,6,7,8-tetrahydropterin synthase
C2I28_14425	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
C2I28_14430	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
C2I28_14435	ENOG4105K4T	epimerase
C2I28_14465	ENOG4105F0V	Cell wall hydrolase
C2I28_14515	ENOG4108K88	Membrane
C2I28_14525	ENOG4108R6K	riboflavin synthase, subunit alpha
C2I28_14535	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
C2I28_14545	ENOG4105CID	antiterminator
C2I28_14555	ENOG4105KRI	phosphocarrier protein (HPr
C2I28_14560	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
C2I28_14565	ENOG41067MG	lrgb family
C2I28_14570	ENOG4105VAW	lrga family
C2I28_14575	ENOG4105CMU	LysR family (Transcriptional regulator
C2I28_14590	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
C2I28_14600	ENOG4105CHM	Aminotransferase
C2I28_14620	ENOG4107R88	Chemotaxis protein (CheV)
C2I28_14625	ENOG4105UIN	
C2I28_14630	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
C2I28_14635	ENOG4107R33	ppx gppa phosphatase
C2I28_14640	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
C2I28_14655	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
C2I28_14660	ENOG4105EPM	Diguanylate phosphodiesterase
C2I28_14675	ENOG4107IN1	Protein of unknown function (DUF1797)
C2I28_14690	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
C2I28_14695	ENOG4105CH2	amidohydrolase
C2I28_14705	ENOG4105D8X	mechanosensitive ion channel
C2I28_14710	ENOG4105D3R	alkyl hydroperoxide reductase
C2I28_14715	ENOG4107R19	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C2I28_14725	ENOG4105BZ1	(ABC) transporter
C2I28_14730	ENOG4105BZ1	(ABC) transporter
C2I28_14735	ENOG4107ZYR	domain protein
C2I28_14740	ENOG4105CN5	Metallo-Beta-Lactamase
C2I28_14745	ENOG4106EHS	UPF0356 protein
C2I28_14750	ENOG4108X4Q	Hydrolase
C2I28_14775	ENOG4105CPP	Dehydrogenase, E1 component
C2I28_14780	ENOG4105C7S	Dehydrogenase
C2I28_14795	ENOG4105C94	Transporter
C2I28_14805	ENOG4105CXN	decarboxylase
C2I28_14810	ENOG4105WBI	UPF0223 protein
C2I28_14830	ENOG4105ECY	inositol monophosphatase
C2I28_14840	ENOG4105CI3	gtp-binding protein typa
C2I28_14845	ENOG4105QA2	
C2I28_14870	ENOG4108IAB	Phoh family
C2I28_14885	ENOG4105CNI	cell division protein FtsW
C2I28_14890	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
C2I28_14895	ENOG4107SGF	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
C2I28_14900	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
C2I28_14935	ENOG41080XQ	Signal transduction protein with cbs domains
C2I28_14940	ENOG4106UY4	Inherit from COG: Scp-like extracellular
C2I28_14955	ENOG4108JYZ	YitT family
C2I28_14960	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
C2I28_14965	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
C2I28_14970	ENOG4108Z5K	methylglyoxal synthase
C2I28_14975	ENOG4105FJR	Lmbe family
C2I28_14980	ENOG4105CPK	Glycosyl transferase (Group 1
C2I28_14985	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
C2I28_14990	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
C2I28_15000	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
C2I28_15005	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
C2I28_15010	ENOG4105DVT	helicase
C2I28_15020	ENOG4105YAC	
C2I28_15030	ENOG4105CHM	Aminotransferase
C2I28_15045	ENOG4105CSM	endonuclease III
C2I28_15055	ENOG4105BZ4	penicillin-binding protein
C2I28_15100	ENOG4106UIA	
C2I28_15110	ENOG4105C28	cystathionine
C2I28_15115	ENOG4105C28	cystathionine
C2I28_15130	ENOG4105CK7	Sodium proline symporter
C2I28_15140	ENOG4105VEQ	Cold shock protein
C2I28_15155	ENOG4105BZU	Histidine kinase
C2I28_15165	ENOG4108I5C	dEAD DEAH box helicase
C2I28_15170	ENOG4107X2U	Inherit from COG: Exonuclease-like protein
C2I28_15180	ENOG4106F55	Protein of unknown function (DUF1273)
C2I28_15185	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
C2I28_15215	ENOG4105WH1	Two component transcriptional regulator luxr family
C2I28_15225	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
C2I28_15240	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
C2I28_15260	ENOG4105DVT	helicase
C2I28_15265	ENOG4105CTD	carboxy-peptidase
C2I28_15270	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
C2I28_15275	ENOG4105C2W	permease
C2I28_15280	ENOG4105F04	LysR family Transcriptional regulator
C2I28_15285	ENOG4105C26	Dehydrogenase
C2I28_15300	ENOG41065KQ	synthase
C2I28_15310	ENOG410890F	Dynamin family
C2I28_15315	ENOG410756H	nucleotidyltransferase
C2I28_15340	ENOG41081VK	Ribonuclease
C2I28_15385	ENOG4108ME1	Peptidase M55 D-aminopeptidase
C2I28_15390	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C2I28_15395	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C2I28_15400	ENOG4105C3U	ABC transporter
C2I28_15410	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
C2I28_15415	ENOG4107SN7	NLP P60 protein
C2I28_15420	ENOG4108JQ7	(ABC) transporter
C2I28_15435	ENOG4105KNA	-acetyltransferase
C2I28_15440	ENOG4105BZU	Histidine kinase
C2I28_15450	ENOG4108PJD	permease
C2I28_15455	ENOG4108HUF	Transporter
C2I28_15460	ENOG4105DQ5	transport system permease protein
C2I28_15465	ENOG4108U1V	ABC transporter, permease
C2I28_15470	ENOG4105E0A	ABC, transporter
C2I28_15500	ENOG4108S01	response regulator
C2I28_15505	ENOG4108ZGX	Histidine kinase
C2I28_15510	ENOG4105ECK	Fatty Acid Desaturase
C2I28_15520	ENOG4105IIP	Membrane
C2I28_15525	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
C2I28_15530	ENOG4108TM9	integral membrane protein
C2I28_15540	ENOG4105K4H	Nlp p60 protein
C2I28_15545	ENOG41087PP	glycosyltransferase MGT family
C2I28_15550	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
C2I28_15580	ENOG4107ZXU	DSBA oxidoreductase
C2I28_15595	ENOG41067TZ	transcriptional regulator, MarR family
C2I28_15600	ENOG4105CW7	secretion protein, HlyD family
C2I28_15605	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C2I28_15610	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
C2I28_15630	ENOG4105EHG	Permease protein
C2I28_15635	ENOG4105DQ5	transport system permease protein
C2I28_15645	ENOG4105E0A	ABC, transporter
C2I28_15650	ENOG4105CAY	ferredoxin--nadp reductase
C2I28_15655	ENOG4105C28	cystathionine
C2I28_15660	ENOG4105C2C	drug resistance transporter, Bcr CflA
C2I28_15680	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
C2I28_15685	ENOG4105KVH	Transcriptional regulator
C2I28_15690	ENOG4108VA3	3-hexulose-6-phosphate synthase
C2I28_15700	ENOG4105F76	Sarcosine oxidase
C2I28_15705	ENOG4105DVW	rieske (2Fe-2S)
C2I28_15710	ENOG4108IJ7	Glycine betaine
C2I28_15725	ENOG4105CA9	Pyruvate kinase
C2I28_15730	ENOG4105BZU	Histidine kinase
C2I28_15735	ENOG4105BZU	Histidine kinase
C2I28_15740	ENOG4108MJI	response regulator
C2I28_15750	ENOG4105CUB	amino acid
C2I28_15765	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
C2I28_15770	ENOG4105EDQ	levansucrase EC 2.4.1.10
C2I28_15775	ENOG4108HKT	sucrose-6-phosphate hydrolase
C2I28_15780	ENOG4108UQY	Iron-storage protein
C2I28_15785	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C2I28_15795	ENOG4105EXW	epimerase dehydratase
C2I28_15800	ENOG4105U7G	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization (By similarity)
C2I28_15805	ENOG4107RGD	Major Facilitator superfamily
C2I28_15820	ENOG4105C26	Dehydrogenase
C2I28_15845	ENOG4105CN5	Metallo-Beta-Lactamase
C2I28_15875	ENOG4105YWU	small acid-soluble spore protein
C2I28_15880	ENOG4105ETE	Transcriptional regulator (LacI family
C2I28_15885	ENOG4105U0F	oligosaccharide H symporter, major facilitator superfamily (MFS)
C2I28_15890	ENOG4108HKT	sucrose-6-phosphate hydrolase
C2I28_15895	ENOG4105CNG	UPF0061 protein
C2I28_15900	ENOG4105EDQ	levansucrase EC 2.4.1.10
C2I28_15905	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C2I28_15910	ENOG4105YHU	PTS system
C2I28_15915	ENOG4108IQ3	PTS system
C2I28_15920	ENOG4105ETZ	PTS System
C2I28_15925	ENOG4105F3R	pts system mannose fructose sorbose family iid
C2I28_15930	ENOG4108HKT	sucrose-6-phosphate hydrolase
C2I28_15935	ENOG4105E5Q	amino acid AbC transporter
C2I28_15950	ENOG4105D01	(LipO)protein
C2I28_15955	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
C2I28_15960	ENOG4108UMI	ABC transporter, permease
C2I28_15965	ENOG4105D01	(LipO)protein
C2I28_15970	ENOG4105CPU	Monooxygenase
C2I28_15975	ENOG4106A4F	Removes the N-terminal methionine from nascent proteins (By similarity)
C2I28_15985	ENOG4108UIN	ybak prolyl-trna synthetase associated region
C2I28_16000	ENOG4105C84	Histidine ammonia-lyase
C2I28_16010	ENOG4105CI2	imidazolone-5-propionate hydrolase
C2I28_16015	ENOG4108903	Formimidoylglutamase
C2I28_16020	ENOG4105DU0	nucleoside hydrolase
C2I28_16035	ENOG4105DYB	Isoaspartyl dipeptidase
C2I28_16065	ENOG41068WN	
C2I28_16085	ENOG4108U05	Transcriptional regulator
C2I28_16090	ENOG41090PH	Protease synthase and sporulation negative regulatory protein pai 1
C2I28_16095	ENOG41082BM	Transcriptional regulator, arsr family
C2I28_16155	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
C2I28_16165	ENOG4105MKU	Transcriptional regulator
C2I28_16175	ENOG4105CV1	Transketolase (EC 2.2.1.1)
C2I28_16180	ENOG4108IUS	Transketolase
C2I28_16190	ENOG41073TP	transcriptional regulator
C2I28_16205	ENOG4108YZG	isomerase
C2I28_16210	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
C2I28_16225	ENOG4105K4H	Nlp p60 protein
C2I28_16230	ENOG4105CNI	cell division protein FtsW
C2I28_16285	ENOG4107V2S	Transcriptional regulator
C2I28_16290	ENOG4108XEP	Alpha Beta Hydrolase Fold protein
C2I28_16320	ENOG4108PSK	reductase
C2I28_16340	ENOG4107ZTW	SNARE associated Golgi
C2I28_16350	ENOG4108ZJ4	polysaccharide deacetylase
C2I28_16375	ENOG4105E1K	spore germination protein
C2I28_16380	ENOG4108XW0	May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF
C2I28_16435	ENOG4105EYF	MMPL domain protein
C2I28_16440	ENOG4108XG4	DNA-binding transcriptional regulator
C2I28_16445	ENOG4107TS3	membrane protein, TerC
C2I28_16460	ENOG4108S3Y	transcriptional regulator
C2I28_16465	ENOG4105VCP	PTS System
C2I28_16475	ENOG4105CS2	ec 3.2.1.21
C2I28_16485	ENOG41066F8	ROK family
C2I28_16505	ENOG4105XDF	Protein of unknown function (DUF1272)
C2I28_16535	ENOG4105KPY	Small multidrug resistance protein
C2I28_16610	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
C2I28_16615	ENOG4105VRS	hydrolase family 18
C2I28_16620	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
C2I28_16660	ENOG4108I0C	methyltransferase
C2I28_16675	ENOG4108MK9	spermidine N(1)-acetyltransferase
C2I28_16690	ENOG4107R5R	arsenical pump membrane protein
C2I28_16695	ENOG41082YX	Transcriptional regulator, arsr family
C2I28_16705	ENOG41085FC	arsR family transcriptional regulator
C2I28_16710	ENOG4108YZ3	Glyoxalase Bleomycin resistance protein (Dioxygenase
C2I28_16720	ENOG4108UZ3	Transporter
C2I28_16725	ENOG4105KVH	Transcriptional regulator
C2I28_16740	ENOG4108R6W	Transcriptional regulator, ARAC family
C2I28_16750	ENOG4105CMT	Dihydroxyacetone kinase
C2I28_16780	ENOG4105D06	uba thif-type nad fad binding protein
C2I28_16825	ENOG4105PGM	cation diffusion facilitator family transporter
C2I28_16845	ENOG4107DUR	UPF0457 protein
C2I28_16855	ENOG4108TYN	CAAX amino terminal protease family protein
C2I28_16900	ENOG4108IJ0	Aspartate ammonia-lyase
C2I28_16905	ENOG4108IND	Tetr family transcriptional regulator
C2I28_16910	ENOG4105E1F	short-chain dehydrogenase reductase
C2I28_16915	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
C2I28_16965	ENOG4108PJD	permease
C2I28_16980	ENOG4105C59	p-type ATPase
C2I28_17015	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
C2I28_17035	ENOG4108JUB	Transcriptional regulator
C2I28_17055	ENOG4107R95	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
C2I28_17075	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C2I28_17085	ENOG4108JQ7	(ABC) transporter
C2I28_17090	ENOG4108Z66	YbaK ebsC protein
C2I28_17105	ENOG4105CSH	Transporter
C2I28_17120	ENOG4105C26	Dehydrogenase
C2I28_17135	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
C2I28_17140	ENOG4108JB8	alcohol dehydrogenase
C2I28_17145	ENOG4107S2N	Type III effector Hrp-dependent
C2I28_17150	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
C2I28_17165	ENOG4105CHR	reductase
C2I28_17195	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
C2I28_17205	ENOG4105EK3	May be involved in the control of utilization of gamma- aminobutyric acid (By similarity)
C2I28_17210	ENOG4105D5U	fad dependent oxidoreductase
C2I28_17220	ENOG4105C1G	acyl-Coa dehydrogenase
C2I28_17225	ENOG4105CEY	Amp-dependent synthetase and ligase
C2I28_17230	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C2I28_17235	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C2I28_17240	ENOG4105C1G	acyl-Coa dehydrogenase
C2I28_17245	ENOG4105CHU	acetyl-coa acetyltransferase
C2I28_17250	ENOG4105CHU	acetyl-coa acetyltransferase
C2I28_17255	ENOG4105E39	Enoyl-CoA hydratase
C2I28_17270	ENOG4105DJB	Major Facilitator Superfamily
C2I28_17275	ENOG4105EA8	2-Nitropropane dioxygenase
C2I28_17280	ENOG4105CEY	Amp-dependent synthetase and ligase
C2I28_17285	ENOG41080XP	Cbs domain
C2I28_17300	ENOG4105E2S	oxidase) subunit II
C2I28_17305	ENOG4105BZ9	Cytochrome C oxidase, subunit I
C2I28_17310	ENOG4105CCU	oxidase (Subunit III)
C2I28_17315	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
C2I28_17320	ENOG4107YZX	Universal stress protein
C2I28_17325	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
C2I28_17330	ENOG4107SGF	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
C2I28_17335	ENOG4105E1J	oxidoreductase
C2I28_17345	ENOG4105C7N	Xanthine uracil vitamin C permease
C2I28_17350	ENOG4108J9M	Transporter
C2I28_17355	ENOG4107RUY	(E1 component), alpha subunit
C2I28_17365	ENOG4107QKR	Dehydrogenase
C2I28_17375	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
C2I28_17380	ENOG4105C28	cystathionine
C2I28_17420	ENOG4105C02	permease
C2I28_17425	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
C2I28_17430	ENOG4105D2H	Uronic isomerase
C2I28_17435	ENOG4105CT4	transporter
C2I28_17440	ENOG4107KJX	Transcriptional regulator
C2I28_17445	ENOG4107QZW	Altronate oxidoreductase
C2I28_17450	ENOG4105CTX	dehydratase
C2I28_17455	ENOG4105DDI	hemolysin-type calcium-binding region
C2I28_17465	ENOG4105CT4	transporter
C2I28_17485	ENOG4107YZX	Universal stress protein
C2I28_17490	ENOG4105BZU	Histidine kinase
C2I28_17495	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C2I28_17500	ENOG4105VPX	protein, conserved in bacteria
C2I28_17505	ENOG410681U	heavy metal transport detoxification protein
C2I28_17510	ENOG4105C59	p-type ATPase
C2I28_17520	ENOG41090UD	(LipO)protein
C2I28_17565	ENOG41082YX	Transcriptional regulator, arsr family
C2I28_17570	ENOG4107R5R	arsenical pump membrane protein
C2I28_17580	ENOG4108VUY	thioesterase Superfamily protein
C2I28_17585	ENOG41081VB	Hydrolase
C2I28_17590	ENOG4108QY0	Membrane
C2I28_17610	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
C2I28_17615	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
C2I28_17620	ENOG4105CZM	Major Facilitator
C2I28_17625	ENOG4105KVH	Transcriptional regulator
C2I28_17630	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
C2I28_17635	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
C2I28_17650	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
C2I28_17660	ENOG4105X5K	response regulator receiver protein
C2I28_17670	ENOG4105KHC	sulfurtransferase
C2I28_17685	ENOG4108ZJ4	polysaccharide deacetylase
C2I28_17725	ENOG4105CVG	Homoserine O-transsuccinylase
C2I28_17740	ENOG4108V06	Glutathione peroxidase
C2I28_17750	ENOG4105C5H	ABC transporter
C2I28_17760	ENOG4108ZJ4	polysaccharide deacetylase
C2I28_17765	ENOG4108Y6J	UPF0403 protein
C2I28_17770	ENOG4107YX5	Pfam:DUF548
C2I28_17780	ENOG4105SZ6	Thioredoxin
C2I28_17785	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
C2I28_17795	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
C2I28_17805	ENOG4108YZT	Adenosylcobinamide kinase
C2I28_17810	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
C2I28_17815	ENOG4105CVJ	phosphoglycerate mutase
C2I28_17825	ENOG4108WBT	adenosyltransferase
C2I28_17830	ENOG4105FR1	rard protein
C2I28_17845	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
C2I28_17850	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
C2I28_17875	ENOG4105II7	pyrroline-5-carboxylate reductase
C2I28_17880	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
C2I28_17885	ENOG4108AEY	RNA polymerase sigma factor
C2I28_17910	ENOG4107QMU	Mate efflux family protein
C2I28_17915	ENOG4105CHR	reductase
C2I28_17950	ENOG4105CDW	Resistance protein
C2I28_17965	ENOG4108ZJ4	polysaccharide deacetylase
C2I28_17975	ENOG4105IIU	Aminopeptidase
C2I28_17980	ENOG4105BZU	Histidine kinase
C2I28_17990	ENOG4107R6U	sodium dicarboxylate symporter
C2I28_17995	ENOG4108IUM	Glycogen debranching enzyme
C2I28_18000	ENOG4105C26	Dehydrogenase
C2I28_18005	ENOG41068W2	Cytochrome p-450
C2I28_18020	ENOG4105E14	MotA TolQ exbB proton channel
C2I28_18025	ENOG4105ER2	Ompa motb domain protein
C2I28_18040	ENOG4108NA0	Uncharacterized conserved protein (COG2071)
C2I28_18045	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
C2I28_18050	ENOG4105DFD	Na H antiporter
C2I28_18065	ENOG4108TGC	Acyltransferase
C2I28_18070	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
C2I28_18075	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C2I28_18080	ENOG4105US7	Histidine kinase
C2I28_18085	ENOG4107RNN	dihydropyrimidinase (EC 3.5.2.2)
C2I28_18090	ENOG4105DUX	Transporter
C2I28_18100	ENOG4105C6K	Malic enzyme
C2I28_18110	ENOG410667J	hydrolase
C2I28_18115	ENOG4105DEN	Luciferase family
C2I28_18125	ENOG4108XSB	acetyltransferase, (GNAT) family
C2I28_18150	ENOG4105CDA	abc transporter atp-binding protein
C2I28_18170	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
C2I28_18210	ENOG4108URH	decarboxylase
C2I28_18220	ENOG410905X	membrane-flanked domain protein
C2I28_18225	ENOG4105CKV	Membrane
C2I28_18240	ENOG4105D7K	pfkb domain protein
C2I28_18245	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
C2I28_18250	ENOG4105K7W	phage-related replication protein
C2I28_18260	ENOG4107SWG	transcriptional regulator MERR family
C2I28_18280	ENOG41069DP	small acid-soluble spore protein
C2I28_18285	ENOG4108R1P	
C2I28_18290	ENOG4105C5Q	Transcriptional regulator
C2I28_18295	ENOG4105CBC	glutamate synthase
C2I28_18300	ENOG4105BZ8	glutamate synthase
C2I28_18320	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
C2I28_18335	ENOG4107RZC	phospholipase d
C2I28_18350	ENOG41061AU	MarR family Transcriptional regulator
C2I28_18360	ENOG41067MG	lrgb family
C2I28_18380	ENOG4105EDW	glycosyl transferase, family 39
C2I28_18385	ENOG4105CKK	Glycosyl transferase, family 2
C2I28_18395	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
C2I28_18400	ENOG4105EFI	regulatoR
C2I28_18420	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
C2I28_18425	ENOG4108I5D	sulfate abc transporter
C2I28_18430	ENOG4105ECW	sulfate abc transporter
C2I28_18445	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C2I28_18470	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
C2I28_18480	ENOG4105E98	transcriptional regulator DeoR family
C2I28_18485	ENOG4105DE4	1-phosphofructokinase
C2I28_18490	ENOG4105DM4	PTS System
C2I28_18495	ENOG4105CFH	Aspartokinase
C2I28_18505	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
C2I28_18510	ENOG4105EWK	phytoene
C2I28_18520	ENOG4108W6C	Dehydrogenase
C2I28_18525	ENOG41082YX	Transcriptional regulator, arsr family
C2I28_18530	ENOG4105C26	Dehydrogenase
C2I28_18535	ENOG4105ETU	transcriptional activator (TenA
C2I28_18550	ENOG4105C8J	)-transporter
C2I28_18555	ENOG4105F0V	Cell wall hydrolase
C2I28_18575	ENOG4105CK5	oxidoreductase
C2I28_18580	ENOG4107QP6	Xylose isomerase domain protein TIM barrel
C2I28_18585	ENOG4108VX5	3-methyladenine DNA glycosylase
C2I28_18595	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
C2I28_18605	ENOG4105I4A	GCN5-related N-acetyltransferase
C2I28_18610	ENOG41062JF	Transcriptional regulator
C2I28_18630	ENOG410606W	general stress protein
C2I28_18665	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
C2I28_18670	ENOG4107T89	von Willebrand factor, type A
C2I28_18675	ENOG4108UZ3	Transporter
C2I28_18695	ENOG4108428	Inherit from COG: -acetyltransferase
C2I28_18700	ENOG4105DKW	ABC transporter
C2I28_18715	ENOG4105EWU	Squalene--hopene cyclase
C2I28_18725	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
C2I28_18735	ENOG4105JAB	phenazine biosynthesis protein, phzf family
C2I28_18750	ENOG4108NGU	Transcriptional regulator
C2I28_18755	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
C2I28_18760	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
C2I28_18780	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
C2I28_18785	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
C2I28_18805	ENOG410756H	nucleotidyltransferase
C2I28_18835	ENOG4105HTX	biosynthesis protein
C2I28_18840	ENOG4107YJ4	chain length determinant protein
C2I28_18850	ENOG4108PQP	glycosyl transferase group 1
C2I28_18855	ENOG4107QRS	glycosyltransferase group 2 family protein
C2I28_18860	ENOG4108KMV	Glycosyl transferase (Group 1
C2I28_18870	ENOG41068W6	Capsular polysaccharide biosynthesis protein
C2I28_18875	ENOG4105CMR	udp-glucose 4-epimerase
C2I28_18880	ENOG4105D3Q	Sugar transferase
C2I28_18885	ENOG4105MME	Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family
C2I28_18890	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
C2I28_18895	ENOG4108IMY	Transcriptional regulator
C2I28_18950	ENOG4105CAQ	asparagine synthetase
C2I28_18955	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
C2I28_18975	ENOG4105BZ1	(ABC) transporter
C2I28_19010	ENOG4105DIN	metallophosphoesterase
C2I28_19025	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
C2I28_19035	ENOG4105DAP	Nicotinate phosphoribosyltransferase
C2I28_19040	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
C2I28_19045	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
C2I28_19050	ENOG41060GV	RNA binding s1 domain protein
C2I28_19055	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
C2I28_19060	ENOG4105DTD	Dehydrogenase
C2I28_19065	ENOG410855V	Acylphosphatase
C2I28_19070	ENOG4105EU0	Major facilitator Superfamily
C2I28_19075	ENOG4105DEN	Luciferase family
C2I28_19085	ENOG4105FTV	AraC Family Transcriptional Regulator
C2I28_19090	ENOG4108RNG	Permease of the drug metabolite transporter
C2I28_19095	ENOG4105C5H	ABC transporter
C2I28_19105	ENOG4108Q8B	Spore germination protein
C2I28_19110	ENOG4108NHD	germination protein
C2I28_19115	ENOG4108V0E	nucleoside 2-deoxyribosyltransferase YtoQ
C2I28_19120	ENOG4105CJ1	ABC, transporter
C2I28_19130	ENOG4107S6Z	Na H antiporter
C2I28_19145	ENOG4105F6S	Spore photoproduct lyase
C2I28_19165	ENOG4105C9U	ATP-dependent DNA helicase RecQ
C2I28_19175	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
C2I28_19205	ENOG4107RZC	phospholipase d
C2I28_19225	ENOG4107S6Z	Na H antiporter
C2I28_19240	ENOG4105E1K	spore germination protein
C2I28_19260	ENOG4105BZU	Histidine kinase
C2I28_19265	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C2I28_19280	ENOG4105DTQ	mandelate racemase muconate lactonizing
C2I28_19285	ENOG4105C26	Dehydrogenase
C2I28_19290	ENOG4108IJ0	Aspartate ammonia-lyase
C2I28_19295	ENOG4105C26	Dehydrogenase
C2I28_19305	ENOG4108JB8	alcohol dehydrogenase
C2I28_19310	ENOG4105C94	Transporter
C2I28_19315	ENOG41073R8	VanW family
C2I28_19355	ENOG4105C9U	ATP-dependent DNA helicase RecQ
C2I28_19370	ENOG4105C26	Dehydrogenase
C2I28_19390	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
C2I28_19395	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
C2I28_19405	ENOG4105KWG	Pfam:DUF1696
C2I28_19410	ENOG4105D94	Major Facilitator Superfamily
C2I28_19415	ENOG4105DUM	transcriptional regulator, lysR family
C2I28_19420	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
C2I28_19425	ENOG4105DVE	abc transporter atp-binding protein
C2I28_19435	ENOG4105EMN	RNA polymerase sigma factor
C2I28_19450	ENOG4108ZHJ	Organic hydroperoxide resistance protein
C2I28_19455	ENOG4105K56	Transcriptional regulator
C2I28_19470	ENOG4105VES	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
C2I28_19480	ENOG41069ER	domain protein
C2I28_19500	ENOG4105BZU	Histidine kinase
C2I28_19505	ENOG4105II7	pyrroline-5-carboxylate reductase
C2I28_19510	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
C2I28_19515	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
C2I28_19530	ENOG4105JSC	dimethylmenaquinone methyltransferase
C2I28_19545	ENOG4107R13	MMPL domain protein
C2I28_19550	ENOG4107TUM	Amidinotransferase
C2I28_19560	ENOG4107U9T	Pfam:Ribonuclease_BN
C2I28_19620	ENOG4106SCS	STAS domain
C2I28_19625	ENOG4106CAD	Protein of unknown function (DUF3311)
C2I28_19630	ENOG4105E1V	na solute symporter
C2I28_19640	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
C2I28_19655	ENOG4105C9Q	fumarate hydratase class II
C2I28_19665	ENOG4107YXZ	hydrolase, family 25
C2I28_19675	ENOG4105BZU	Histidine kinase
C2I28_19715	ENOG4108RCM	Nitroreductase
C2I28_19725	ENOG4108IXY	short-chain dehydrogenase reductase
C2I28_19730	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
C2I28_19735	ENOG4108V9W	transcriptional regulatory protein
C2I28_19740	ENOG4105D4T	Citrate transporter
C2I28_19750	ENOG4105CY2	Citrate transporter
C2I28_19755	ENOG4105DTD	Dehydrogenase
C2I28_19760	ENOG4105CIN	aminoacyl-histidine dipeptidase
C2I28_19780	ENOG4105CMU	LysR family (Transcriptional regulator
C2I28_19790	ENOG4105CK2	sodium dicarboxylate symporter
C2I28_19795	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
C2I28_19805	ENOG4107VFR	oxidoreductase
C2I28_19815	ENOG4105BZU	Histidine kinase
C2I28_19830	ENOG4105CHR	reductase
C2I28_19835	ENOG4105CEY	Amp-dependent synthetase and ligase
C2I28_19845	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C2I28_19850	ENOG4105E39	Enoyl-CoA hydratase
C2I28_19865	ENOG4108N5B	2-phosphosulfolactate phosphatase
C2I28_19870	ENOG4105C1G	acyl-Coa dehydrogenase
C2I28_19875	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
C2I28_19880	ENOG4105CGU	Enoyl-CoA hydratase
C2I28_19890	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
C2I28_19905	ENOG4107QP7	CoA-transferase subunit A
C2I28_19910	ENOG4108IIH	CoA-transferase subunit B
C2I28_19915	ENOG4105CHU	acetyl-coa acetyltransferase
C2I28_19920	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
C2I28_19925	ENOG4108JPW	Aminotransferase
C2I28_19945	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
C2I28_19955	ENOG4108IQI	permease
C2I28_19960	ENOG4105C5X	domain protein
C2I28_19965	ENOG4106XGU	
C2I28_19985	ENOG4105CPF	Cell wall formation (By similarity)
C2I28_19995	ENOG4108594	Permease of the drug metabolite transporter
C2I28_20005	ENOG4105JKW	Valine--pyruvate aminotransferase
C2I28_20015	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
C2I28_20020	ENOG4105F0V	Cell wall hydrolase
C2I28_20030	ENOG4105CBG	Sulfatase
C2I28_20035	ENOG4105C22	threonyL-tRNA synthetase
C2I28_20045	ENOG4105CUB	amino acid
C2I28_20050	ENOG4105F27	Major Facilitator
C2I28_20055	ENOG41062A4	Transcriptional regulator
C2I28_20060	ENOG4105EYF	MMPL domain protein
C2I28_20065	ENOG4105BZU	Histidine kinase
C2I28_20075	ENOG41082BM	Transcriptional regulator, arsr family
C2I28_20090	ENOG4107YUH	hydrolase
C2I28_20100	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
C2I28_20115	ENOG4105NX3	Membrane
C2I28_20125	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
C2I28_20130	ENOG4108JQ1	Dehydrogenase
C2I28_20150	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
C2I28_20165	ENOG4107Y9U	Membrane
C2I28_20190	ENOG4105EUZ	Beta-lactamase domain protein
C2I28_20195	ENOG4105D82	Glutamate dehydrogenase
C2I28_20245	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
C2I28_20260	ENOG4105P8F	nudix hydrolase
C2I28_20275	ENOG41067TZ	transcriptional regulator, MarR family
C2I28_20280	ENOG41073R8	VanW family
C2I28_20285	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
C2I28_20325	ENOG4105CVK	Glutamate decarboxylase
C2I28_20350	ENOG4105TMB	Formate nitrite transporter
C2I28_20355	ENOG4108ZSU	Uncharacterized conserved protein (DUF2294)
C2I28_20375	ENOG4105IQ5	FAD linked oxidase domain protein
C2I28_20380	ENOG4105C8Q	Methyl-accepting chemotaxis
C2I28_20390	ENOG4108RE9	Phosphodiesterase
C2I28_20400	ENOG4105DIN	metallophosphoesterase
C2I28_20405	ENOG4108VCA	G U mismatch-specific DNA glycosylase
C2I28_20415	ENOG4105EXQ	uroporphyrinogen iii synthase hem4
C2I28_20420	ENOG4107258	Transcriptional regulator
C2I28_20425	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
C2I28_20440	ENOG4105P4J	Allophanate hydrolase, subunit 1
C2I28_20445	ENOG4105CFM	UPF0317 protein
C2I28_20450	ENOG4105C5A	transporter
C2I28_20455	ENOG4105E7W	lamb ycsf family protein
C2I28_20460	ENOG4105CG3	alpha amylase, catalytic region
C2I28_20470	ENOG4108V4B	ThiJ pfpI
C2I28_20480	ENOG4107T5V	SNARE associated Golgi
C2I28_20510	ENOG4105JQZ	Methyltransferase
C2I28_20540	ENOG4105RHY	Pfam:UPF0157
C2I28_20580	ENOG4107F3J	Amp-dependent synthetase and ligase
C2I28_20585	ENOG4107ZYJ	bioY protein
C2I28_20595	ENOG4105JAS	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity)
C2I28_20615	ENOG4105WH1	Two component transcriptional regulator luxr family
C2I28_20620	ENOG4105BZU	Histidine kinase
C2I28_20650	ENOG41082BV	acetyltransferase
C2I28_20655	ENOG4105C01	Dihydroxy-acid dehydratase
C2I28_20660	ENOG4105E5G	Alpha beta hydrolase fold
C2I28_20665	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
C2I28_20685	ENOG4105CM2	brancheD-chain amino acid aminotransferase
C2I28_20695	ENOG4105F6E	Acyl-transferase
C2I28_20705	ENOG4105FFA	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin (By similarity)
C2I28_20710	ENOG4105VT2	5-hydroxyisourate hydrolase
C2I28_20715	ENOG4108MK9	spermidine N(1)-acetyltransferase
C2I28_20730	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
C2I28_20745	ENOG4105U0R	haloacid dehalogenase-like hydrolase
C2I28_20750	ENOG4105RV9	Transcriptional regulator
C2I28_20760	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C2I28_20775	ENOG4107R55	ethanolamine transporter
C2I28_20780	ENOG4107FQ9	ethanolamine ammonia-lyase
C2I28_20785	ENOG4105CPD	ethanolamine ammonia-lyase
C2I28_20790	ENOG4105DYY	Reactivating factor for ethanolamine ammonia lyase
C2I28_20800	ENOG4108IQI	permease
C2I28_20810	ENOG4108Z7F	N-acetyltransferase
C2I28_20835	ENOG4107S9D	Alpha beta hydrolase
C2I28_20845	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C2I28_20850	ENOG4105K4P	CoA-binding domain protein
C2I28_20855	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
C2I28_20860	ENOG4105W8X	HesB YadR YfhF-family protein
C2I28_20875	ENOG41067CD	Small, acid-soluble spore protein Tlp
C2I28_20885	ENOG41075ZD	Small, acid-soluble spore protein N
C2I28_20895	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C2I28_20900	ENOG4108I0Z	Aconitate hydratase
C2I28_20905	ENOG410746C	Acid-soluble spore protein O
C2I28_20910	ENOG4107DZX	Small, acid-soluble spore protein P
C2I28_20920	ENOG4105FDF	Could be involved in DNA repair (By similarity)
C2I28_20955	ENOG4105C7W	Xanthine dehydrogenase
C2I28_20965	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
C2I28_21025	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
C2I28_21040	ENOG4105F27	Major Facilitator
C2I28_21055	ENOG4105VBF	alkaline shock protein
C2I28_21070	ENOG4107U9T	Pfam:Ribonuclease_BN
C2I28_21080	ENOG4105BZG	amino acid carrier protein
C2I28_21085	ENOG4105C6X	Major Facilitator
C2I28_21095	ENOG4105DXB	Major Facilitator superfamily
C2I28_21100	ENOG4107SWG	transcriptional regulator MERR family
C2I28_21110	ENOG4108V2W	Carbonate dehydratase
C2I28_21115	ENOG4105CHH	sulfate transporter
C2I28_21120	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C2I28_21140	ENOG4107QTZ	amino acid
C2I28_21150	ENOG4108ZRV	stage ii sporulation protein p
C2I28_21155	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
C2I28_21165	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
C2I28_21170	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
C2I28_21175	ENOG4108P62	biosynthesis protein (CbiG)
C2I28_21180	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
C2I28_21190	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
C2I28_21195	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
C2I28_21200	ENOG41081F0	Precorrin-8x methylmutase
C2I28_21205	ENOG4108JTQ	reductase
C2I28_21210	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
C2I28_21215	ENOG4105E4R	Precorrin-3B C17-methyltransferase
C2I28_21225	ENOG4105DER	m42 family
C2I28_21275	ENOG4107TT2	Auxin Efflux Carrier
C2I28_21280	ENOG4105C6K	Malic enzyme
C2I28_21285	ENOG4107RT5	aminobenzoyl-glutamate utilization protein B
C2I28_21290	ENOG4105DJB	Major Facilitator Superfamily
C2I28_21300	ENOG41069ZX	
C2I28_21305	ENOG41069ZX	
C2I28_21310	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
C2I28_21315	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
C2I28_21320	ENOG4106P55	Transcriptional regulator
C2I28_21325	ENOG4107TT2	Auxin Efflux Carrier
C2I28_21345	ENOG4105DEN	Luciferase family
C2I28_21350	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
C2I28_21355	ENOG4105CQB	FAD linked oxidase domain protein
C2I28_21365	ENOG4107R7Y	intracellular protease Pfpi family
C2I28_21375	ENOG4105CY2	Citrate transporter
C2I28_21380	ENOG4105C0A	alcohol dehydrogenase
C2I28_21395	ENOG4105CJ1	ABC, transporter
C2I28_21405	ENOG4105WH1	Two component transcriptional regulator luxr family
C2I28_21410	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
C2I28_21440	ENOG4105DEN	Luciferase family
C2I28_21450	ENOG4107T5V	SNARE associated Golgi
C2I28_21455	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
C2I28_21460	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
C2I28_21530	ENOG4105UQX	Mate efflux family protein
C2I28_21535	ENOG4105CW7	secretion protein, HlyD family
C2I28_21545	ENOG4105FS7	Transcriptional regulator
C2I28_21550	ENOG4105CGK	Exodeoxyribonuclease III
C2I28_21555	ENOG41090KN	UPF0303 protein
C2I28_21560	ENOG4105D9R	oxidoreductase
C2I28_21565	ENOG4105E98	transcriptional regulator DeoR family
C2I28_21575	ENOG4108TTB	tellurium resistance protein
C2I28_21580	ENOG4106FN3	tellurium resistance protein
C2I28_21585	ENOG4106FN3	tellurium resistance protein
C2I28_21590	ENOG4108N0M	stress protein
C2I28_21595	ENOG4105CGH	5'-nucleotidase
C2I28_21615	ENOG4108TU7	Inherit from COG: (ABC) transporter
C2I28_21620	ENOG4105CJ1	ABC, transporter
C2I28_21630	ENOG4106KE4	Dehydrogenase
C2I28_21640	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
C2I28_21690	ENOG4105CYC	Transferase
C2I28_21695	ENOG4105DY9	regulatoR
C2I28_21700	ENOG4105H67	Protein of unknown function (DUF421)
C2I28_21705	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C2I28_21710	ENOG41069ER	domain protein
C2I28_21715	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
C2I28_21740	ENOG4105EC3	peptidase S51, dipeptidase E
C2I28_21765	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
C2I28_21805	ENOG4105DWT	malate dehydrogenase (quinone)
C2I28_21910	ENOG4107EV6	Inherit from COG: YD repeat protein
C2I28_21940	ENOG4105I1K	ABC transporter
C2I28_21945	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
C2I28_21960	ENOG4108UB7	
C2I28_21970	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
C2I28_21995	ENOG4105BZW	Glycerate kinase
C2I28_22000	ENOG4107QQ0	gntp family
C2I28_22005	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
C2I28_22010	ENOG4108JUB	Transcriptional regulator
C2I28_22020	ENOG4105C0A	alcohol dehydrogenase
C2I28_22025	ENOG4105KAF	membrAne
C2I28_22040	ENOG4105C3M	thioredoxin reductase
C2I28_22060	ENOG4105KAF	membrAne
C2I28_22065	ENOG4105KAF	membrAne
C2I28_22080	ENOG4105IW1	AmiS UreI transporter
C2I28_22085	ENOG4105D9N	nucleoside
C2I28_22095	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
C2I28_22110	ENOG4107RHR	regulatoR
C2I28_22140	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
C2I28_22145	ENOG4105D0M	Protease HtpX homolog
C2I28_22150	ENOG41069FQ	Metallo-beta-lactamase superfamily
C2I28_22155	ENOG4105KK4	UPF0060 membrane protein
C2I28_22165	ENOG4107FKK	extracellular solute-binding protein family 1
C2I28_22185	ENOG4105CRW	Short chain fatty acid transporter
C2I28_22215	ENOG4105CUC	YeeE YedE family protein
C2I28_22230	ENOG4107QW4	alcohol dehydrogenase
C2I28_22235	ENOG4107V2S	Transcriptional regulator
C2I28_22245	ENOG4105GIG	
C2I28_22285	ENOG4105CHR	reductase
C2I28_22290	ENOG4105CPQ	Dehydrogenase
C2I28_22315	ENOG4107SUZ	Sodium/hydrogen exchanger family
C2I28_22320	ENOG4105C37	(CBS) domain
C2I28_22330	ENOG4105EXU	Membrane
C2I28_22345	ENOG4108JQ7	(ABC) transporter
C2I28_22355	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C2I28_22360	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C2I28_22365	ENOG4107RRN	ABC transporter substrate-binding protein
C2I28_22375	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
C2I28_22405	ENOG4105DWT	malate dehydrogenase (quinone)
C2I28_22410	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
C2I28_22415	ENOG4105J7I	hydrolase
C2I28_22430	ENOG4105D8X	mechanosensitive ion channel
C2I28_22465	ENOG4107HP6	Transcriptional regulator
C2I28_22475	ENOG4105C82	Malate synthase
C2I28_22480	ENOG4105CQB	FAD linked oxidase domain protein
C2I28_22485	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
C2I28_22490	ENOG4105CQB	FAD linked oxidase domain protein
C2I28_22495	ENOG4105DAA	L-lactate
C2I28_22520	ENOG4105DA5	(ABC) transporter
C2I28_22525	ENOG41069JR	
C2I28_22565	ENOG4107I77	yiaA/B two helix domain
C2I28_22580	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
C2I28_22585	ENOG4106SCS	STAS domain
C2I28_22590	ENOG4105D7N	magnesium and cobalt transport protein CorA
C2I28_22595	ENOG4108JPV	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
C2I28_22605	ENOG4105H67	Protein of unknown function (DUF421)
C2I28_22610	ENOG4108VXD	carboxy-peptidase
C2I28_22620	ENOG4105BZU	Histidine kinase
C2I28_22625	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
C2I28_22650	ENOG4105C7S	Dehydrogenase
C2I28_22655	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
C2I28_22670	ENOG4108X3M	OsmC Ohr family protein
C2I28_22680	ENOG4105DHF	Membrane
C2I28_22740	ENOG4105BZU	Histidine kinase
C2I28_22745	ENOG4105CFC	Transporter
C2I28_22760	ENOG4105D74	hydrolase
C2I28_22775	ENOG4105RHY	Pfam:UPF0157
C2I28_22780	ENOG4105FDT	acyl-CoA dehydrogenase
C2I28_22820	ENOG4108IPW	abc transporter atp-binding protein
C2I28_22825	ENOG4105EHG	Permease protein
C2I28_22830	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
C2I28_22840	ENOG4107QTZ	amino acid
C2I28_22850	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
C2I28_22860	ENOG41080HJ	6-phospho 3-hexuloisomerase
C2I28_22880	ENOG4105DJB	Major Facilitator Superfamily
C2I28_22885	ENOG4105D7K	pfkb domain protein
C2I28_22900	ENOG4105EWK	phytoene
C2I28_22905	ENOG4105K64	Glycosyl transferase, family 2
C2I28_22960	ENOG4108YZ9	Urea amidohydrolase subunit gamma
C2I28_22965	ENOG4108I0Q	anthranilate phosphoribosyltransferase
C2I28_22975	ENOG41069ER	domain protein
C2I28_22980	ENOG4108DBC	nitroreductase
C2I28_22990	ENOG4107ZTW	SNARE associated Golgi
C2I28_23000	ENOG4105FBA	Phospholipase Carboxylesterase
C2I28_23005	ENOG4105BZ4	penicillin-binding protein
C2I28_23015	ENOG4105T38	integral membrane protein
C2I28_23040	ENOG4105BZ1	(ABC) transporter
C2I28_23065	ENOG4105K7W	phage-related replication protein
C2I28_23075	ENOG4108RMU	ferritin dps family protein
C2I28_23090	ENOG4105C37	(CBS) domain
C2I28_23105	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
C2I28_23130	ENOG4105EVN	Prephenate dehydrogenase
C2I28_23140	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
C2I28_23150	ENOG4105FGV	Chromate
C2I28_23155	ENOG4105CAH	Chromate
C2I28_23160	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
C2I28_23165	ENOG4105C5R	Aminotransferase
C2I28_23175	ENOG4105G9B	Transcriptional regulator
C2I28_23190	ENOG4105CH6	catalase
C2I28_23200	ENOG4105C8J	)-transporter
C2I28_23240	ENOG410635A	Membrane
C2I28_23245	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C2I28_23250	ENOG4105C3F	Signal peptidase i
C2I28_23270	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
C2I28_23295	ENOG4105YVS	arsR family transcriptional regulator
C2I28_23305	ENOG4108DBC	nitroreductase
C2I28_23320	ENOG4105RHY	Pfam:UPF0157
C2I28_23325	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
C2I28_23330	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
C2I28_23345	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
C2I28_23355	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
C2I28_23360	ENOG4108JYZ	YitT family
C2I28_23380	ENOG4107AYK	membrAne
C2I28_23385	ENOG4109050	May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG)
C2I28_23395	ENOG4105BZN	citrate synthase
C2I28_23400	ENOG4105CMU	LysR family (Transcriptional regulator
C2I28_23420	ENOG4105BZU	Histidine kinase
C2I28_23460	ENOG4107BMA	Transglycosylase associated protein
C2I28_23470	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
C2I28_23485	ENOG4108IJ0	Aspartate ammonia-lyase
C2I28_23490	ENOG4105HDK	L-asparaginase
C2I28_23495	ENOG4108IMY	Transcriptional regulator
C2I28_23505	ENOG4105CT4	transporter
C2I28_23510	ENOG4105WAB	arsR family transcriptional regulator
C2I28_23530	ENOG4107QTZ	amino acid
C2I28_23535	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
C2I28_23560	ENOG4105C6K	Malic enzyme
C2I28_23565	ENOG4108AQF	aminoglycoside N(3)-acetyltransferase
C2I28_23575	ENOG41068WN	
C2I28_23580	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
C2I28_23590	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
C2I28_23595	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
C2I28_23605	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C2I28_23610	ENOG41067TZ	transcriptional regulator, MarR family
C2I28_23615	ENOG4107TXC	Transcriptional regulator
C2I28_23620	ENOG4108MK9	spermidine N(1)-acetyltransferase
C2I28_23675	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C2I28_23700	ENOG4105VCH	membrane
C2I28_23710	ENOG4105CI2	imidazolone-5-propionate hydrolase
C2I28_23720	ENOG4108KGH	TRANSCRIPTIONal
C2I28_23725	ENOG41068WN	
C2I28_23745	ENOG41060D1	Quinol oxidase
C2I28_23755	ENOG4105BZ9	Cytochrome C oxidase, subunit I
C2I28_23760	ENOG4105E2S	oxidase) subunit II
C2I28_23795	ENOG4107UX3	phosphatidylethanolamine N-methyltransferase
C2I28_23810	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
C2I28_23815	ENOG410829K	Lysine exporter protein (Lyse ygga)
C2I28_23820	ENOG4107QTZ	amino acid
C2I28_23840	ENOG41087NI	Sulfite exporter TauE/SafE
C2I28_23850	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
C2I28_23860	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
C2I28_23885	ENOG4108JYZ	YitT family
C2I28_23905	ENOG4108R9S	DSBA oxidoreductase
C2I28_23910	ENOG4105D0M	Protease HtpX homolog
C2I28_23945	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
C2I28_23955	ENOG4105Y7M	Transcriptional regulator, TetR family
C2I28_23960	ENOG410814C	multidrug resistance protein
C2I28_23965	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
C2I28_23970	ENOG4105VEQ	Cold shock protein
C2I28_23975	ENOG4108QY0	Membrane
C2I28_23990	ENOG4108RYK	Nad-dependent epimerase dehydratase
C2I28_24020	ENOG4108IPW	abc transporter atp-binding protein
C2I28_24025	ENOG4105CM4	permease protein
C2I28_24030	ENOG4105DHS	permease protein
C2I28_24035	ENOG4105F0V	Cell wall hydrolase
C2I28_24055	ENOG4105NF4	modulator of drug activity
C2I28_24060	ENOG4105C3F	Signal peptidase i
C2I28_24090	ENOG4108UMN	azlc family
C2I28_24095	ENOG4108JCI	Transcriptional regulator
C2I28_24100	ENOG4108ZCF	integral membrane protein
C2I28_24110	ENOG41062ES	Transcriptional regulator
C2I28_24135	ENOG4105NAE	bifunctional deaminase-reductase domain protein
C2I28_24145	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
C2I28_24150	ENOG41067SE	Tetr family transcriptional regulator
C2I28_24160	ENOG4105WEF	catalase
C2I28_24180	ENOG4105N14	lysine exporter protein LysE YggA
C2I28_24185	ENOG4106AXJ	AraC family transcriptional regulator
C2I28_24190	ENOG4108XG2	Histidine kinase
C2I28_24255	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
C2I28_24275	ENOG41083WA	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
C2I28_24290	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
C2I28_24295	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
C2I28_24300	ENOG4105BZU	Histidine kinase
C2I28_24305	ENOG4105EFI	regulatoR
C2I28_24310	ENOG4105JAB	phenazine biosynthesis protein, phzf family
C2I28_24325	ENOG4105BZU	Histidine kinase
C2I28_24330	ENOG4105D9U	N-acetyltransferase
C2I28_24355	ENOG4107QM2	Aldo Keto reductase
C2I28_24365	ENOG4108UZ3	Transporter
C2I28_24370	ENOG4108MCI	Transcriptional regulator, ARAC family
C2I28_24385	ENOG4105W2E	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth (By similarity)
C2I28_24395	ENOG4107ETC	gas vesicle protein
C2I28_24425	ENOG4105MRC	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth
C2I28_24440	ENOG4105MRC	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth
C2I28_24445	ENOG4107KM7	Heat induced stress protein YflT
C2I28_24455	ENOG4105EGI	Transcriptional regulator
C2I28_24460	ENOG41081I9	integral membrane protein
C2I28_24470	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
C2I28_24500	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
C2I28_24505	ENOG4105F6J	Alpha beta hydrolase fold
C2I28_24515	ENOG4108IYU	L-aspartate oxidase
C2I28_24520	ENOG41079KZ	Major Facilitator Superfamily
C2I28_24525	ENOG4108MK9	spermidine N(1)-acetyltransferase
C2I28_24545	ENOG4105CJZ	response regulator
C2I28_24550	ENOG4105EWM	Histidine kinase
C2I28_24555	ENOG4105C19	ABC transporter
C2I28_24560	ENOG4108HVR	ABC transporter, permease
C2I28_24575	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
C2I28_24590	ENOG41087NI	Sulfite exporter TauE/SafE
C2I28_24595	ENOG4105VFE	sira family
C2I28_24600	ENOG4107TPS	domain protein
C2I28_24605	ENOG4105VFE	sira family
C2I28_24615	ENOG4105C72	UPF0176 protein
C2I28_24620	ENOG4105HF9	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
C2I28_24625	ENOG4105VFE	sira family
C2I28_24630	ENOG4105XTG	Pfam:DUF156
C2I28_24660	ENOG4105GZI	Transcriptional regulator
C2I28_24685	ENOG4108S3Y	transcriptional regulator
C2I28_24695	ENOG4105CS2	ec 3.2.1.21
C2I28_24705	ENOG4105X3H	Excalibur domain protein
C2I28_24720	ENOG4105N14	lysine exporter protein LysE YggA
C2I28_24725	ENOG41080UX	Methyltransferase
C2I28_24735	ENOG4107RSM	transcriptional regulator
C2I28_24740	ENOG4105D94	Major Facilitator Superfamily
C2I28_24775	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
C2I28_24785	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
C2I28_24790	ENOG4108TVJ	Nitroreductase
C2I28_24795	ENOG4105C26	Dehydrogenase
C2I28_24810	ENOG4108V0P	LemA family
C2I28_24830	ENOG4105KVH	Transcriptional regulator
C2I28_24835	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
C2I28_24840	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
C2I28_24845	ENOG41068WN	
C2I28_24905	ENOG4108W15	Protein of unknown function (DUF1456)
C2I28_24915	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
C2I28_24945	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
C2I28_24955	ENOG4105DJ2	Major Facilitator Superfamily
C2I28_24960	ENOG4105C6F	GntR Family Transcriptional Regulator
C2I28_25010	ENOG4105CHH	sulfate transporter
C2I28_25020	ENOG4105CT4	transporter
C2I28_25025	ENOG4105C8M	UPF0272 protein
C2I28_25030	ENOG4105C8M	UPF0272 protein
C2I28_25035	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
C2I28_25040	ENOG4105DVM	PP-loop domain protein
C2I28_25045	ENOG4105DMW	Dehydrogenase reductase
C2I28_25055	ENOG4105D2H	Uronic isomerase
C2I28_25095	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
C2I28_25115	ENOG4105CNI	cell division protein FtsW
C2I28_25150	ENOG4108X4Q	Hydrolase
C2I28_25175	ENOG4105KAC	Antibiotic biosynthesis monooxygenase
C2I28_25185	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
C2I28_25200	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C2I28_25215	ENOG4105CJ1	ABC, transporter
C2I28_25230	ENOG4105CHH	sulfate transporter
C2I28_25245	ENOG410900G	Protein of unknown function (DUF421)
C2I28_25265	ENOG4105EGI	Transcriptional regulator
C2I28_25285	ENOG4105DQ4	alcohol dehydrogenase
C2I28_25290	ENOG4105VUF	Transcriptional regulator
C2I28_25305	ENOG4108VK3	Cupin 2 Conserved Barrel Domain Protein
C2I28_25330	ENOG4105VEQ	Cold shock protein
C2I28_25345	ENOG4105C8Q	Methyl-accepting chemotaxis
C2I28_25350	ENOG4105BZU	Histidine kinase
C2I28_25355	ENOG4108VXD	carboxy-peptidase
C2I28_25360	ENOG4107QKS	N-acylglucosamine 2-epimerase
C2I28_25380	ENOG4106SCS	STAS domain
C2I28_25390	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
C2I28_25415	ENOG4105F1N	DNA alkylation repair
C2I28_25445	ENOG4105JXH	GntR family transcriptional regulator
C2I28_25465	ENOG4105XPP	Protein of unknown function (DUF1275)
C2I28_25475	ENOG4105E98	transcriptional regulator DeoR family
C2I28_25480	ENOG410667J	hydrolase
C2I28_25490	ENOG4105C5I	Dehydrogenase
C2I28_25535	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
C2I28_25545	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
C2I28_25565	ENOG4107QNK	)-transporter
C2I28_25570	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
C2I28_25580	ENOG4105CMG	Carbohydrate kinase
C2I28_25585	ENOG4105CMD	Transcriptional regulator, GntR family
C2I28_25610	ENOG4105CE1	Ferrous iron transport protein b
C2I28_25615	ENOG4105CE1	Ferrous iron transport protein b
C2I28_25620	ENOG4105CE1	Ferrous iron transport protein b
C2I28_25635	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
C2I28_25700	ENOG4108RPX	mosc domain containing protein
C2I28_25710	ENOG4105D9N	nucleoside
C2I28_25720	ENOG4105C6Z	Gluconate
C2I28_25725	ENOG4105C01	Dihydroxy-acid dehydratase
C2I28_25730	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
C2I28_25735	ENOG4105DJB	Major Facilitator Superfamily
C2I28_25750	ENOG4107HP6	Transcriptional regulator
C2I28_25800	ENOG4108ZMX	Domain of unknown function (DU1801)
C2I28_25805	ENOG4105CZ9	Domain of unknown function (DU1801)
C2I28_25815	ENOG4106ANW	SMI1_KNR4
C2I28_25935	ENOG4105CB2	alcohol dehydrogenase
C2I28_25945	ENOG4105KVH	Transcriptional regulator
C2I28_25970	ENOG41090E6	transcriptional regulator MERR family
C2I28_25980	ENOG4105DJB	Major Facilitator Superfamily
C2I28_25985	ENOG4105CXK	mandelate racemase muconate lactonizing
C2I28_25995	ENOG4105D7K	pfkb domain protein
C2I28_26000	ENOG4105J4Q	Transcriptional regulator
C2I28_26035	ENOG4105FDP	GntR family transcriptional regulator
C2I28_26045	ENOG4105CJQ	hydrolase, family 31
C2I28_26055	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
C2I28_26060	ENOG4105CT4	transporter
C2I28_26085	ENOG4105JVQ	RNA Polymerase
C2I28_26090	ENOG4105BZU	Histidine kinase
C2I28_26100	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C2I28_26105	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C2I28_26115	ENOG4105DHF	Membrane
C2I28_26165	ENOG41067QW	Transcriptional regulator
C2I28_26170	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
C2I28_26220	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
C2I28_26225	ENOG4105BZU	Histidine kinase
C2I28_26230	ENOG4107QQR	Sporulation
C2I28_26275	ENOG4105E80	TraG TraD family protein
C2I28_26305	ENOG4105K4H	Nlp p60 protein
C2I28_26320	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
C2I28_26325	ENOG4105BZU	Histidine kinase
C2I28_26330	ENOG4107QQR	Sporulation
C2I28_26375	ENOG4105E80	TraG TraD family protein
C2I28_26405	ENOG4105K4H	Nlp p60 protein
C2I28_26455	ENOG4105G7B	Protein of unknown function (DUF2992)
C2I28_26460	ENOG4108RWN	rrna methyltransferase
C2I28_26465	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
C2I28_26480	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
C2I28_26485	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
C2I28_26490	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
C2I28_26500	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
C2I28_26505	ENOG4108ES0	acetoacetyl-CoA synthetase
C2I28_26530	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
C2I28_26580	ENOG4105CNI	cell division protein FtsW
C2I28_26700	ENOG4108RDQ	ABC transporter
C2I28_26715	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
C2I28_26740	ENOG4105C6Z	Gluconate
C2I28_26745	ENOG4105FDP	GntR family transcriptional regulator
C2I28_26765	ENOG41069H0	dihydroorotase EC 3.5.2.3
C2I28_26785	ENOG4107R8N	Glycosyl transferase, family 2
C2I28_26810	ENOG4105K70	DNA-binding protein
C2I28_26815	ENOG4105YWU	small acid-soluble spore protein
C2I28_26840	ENOG4105N14	lysine exporter protein LysE YggA
C2I28_26850	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
C2I28_26925	ENOG4106H3A	restriction
C2I28_26955	ENOG4105C37	(CBS) domain
C2I28_26975	ENOG41082BM	Transcriptional regulator, arsr family
C2I28_27015	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
C2I28_27070	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
C2I28_27075	ENOG4105BZU	Histidine kinase
C2I28_27125	ENOG4105E80	TraG TraD family protein
C2I28_27170	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
C2I28_27175	ENOG4105BZU	Histidine kinase
C2I28_27180	ENOG4107QQR	Sporulation
C2I28_27225	ENOG4105E80	TraG TraD family protein
C2I28_27375	ENOG4105CPK	Glycosyl transferase (Group 1
C2I28_27415	ENOG4105K64	Glycosyl transferase, family 2
C2I28_27430	ENOG4105K64	Glycosyl transferase, family 2
C2I28_27445	ENOG4105K64	Glycosyl transferase, family 2
C2I28_27480	ENOG4105C5E	polysaccharide biosynthesis protein
C2I28_27485	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
C2I28_27525	ENOG4105DNP	FAD linked oxidase domain protein